Cited by 5,784Cardiovascular Health and Risk FactorsHealthcare Systems and Public HealthHealth Promotion and Cardiovascular Prevention

The DOI matches its Crossref record; 255 of the 255 references it cites were found in a registry or an index.

Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association

Open access

Virani, Salim S., Alonso, Alvaro, Aparicio, Hugo J., Benjamin, Emelia J., Bittencourt, Marcio S., Callaway, Clifton W., Carson, April P., Chamberlain, Alanna M., Cheng, Susan, Delling, Francesca N., Elkind, Mitchell S.V., Evenson, Kelly R., Ferguson, Jane F., Gupta, Deepak K., Khan, Sadiya S., Kissela, Brett M., Knutson, Kristen L., Lee, Chong D., Lewis, Tené T., Liu, Junxiu, Loop, Matthew Shane, Lutsey, Pamela L., Ma, Jun, Mackey, Jason, Martin, Seth S., Matchar, David B., Mussolino, Michael E., Navaneethan, Sankar D., Perak, Amanda Marma, Roth, Gregory A., Samad, Zainab, Satou, Gary M., Schroeder, Emily B., Shah, Svati H., Shay, Christina M., Stokes, Andrew, VanWagner, Lisa B., Wang, Nae-Yuh, Tsao, Connie W., On behalf of the American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee·2021·Circulation

DOI 10.1161/cir.0000000000000950PMC PMC13036842

Open this paper in CoChat — free account Open PDF

Abstract

Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). Methods: The American Heart Association, through its Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update. The 2021 Statistical Update is the product of a full year’s worth of effort by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. This year’s edition includes data on the monitoring and benefits of cardiovascular health in the population, an enhanced focus on social determinants of health, adverse pregnancy outcomes, vascular contributions to brain health, the global burden of cardiovascular disease, and further evidence-based approaches to changing behaviors related to cardiovascular disease. Results: Each of the 27 chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. Conclusions: The Statistical Update represents a critical resource for the lay public, policy makers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1161/cir.0000000000000950

Cites

0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

2 retracted

Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N Engl J Med 2013;368:1279-90.
Estruch, R., Ros, E., Salas-Salvadó, J., Covas, M.-I., Corella, D., Arós, F., Gómez-Gracia, E., Ruiz-Gutiérrez, V., Fiol, M., Lapetra, J., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmc1806491 · Cited by 1,008
Retracted
RETRACTED: Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality
Banegas, J. R., Ruilope, L. M., de la Sierra, A., Vinyoles, E., Gorostidi, M., de la Cruz, J. J., Ruiz-Hurtado, G., Segura, J., Rodríguez-Artalejo, F., & Williams, B. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1712231 · Cited by 490
Retracted
Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
Vos, T., Lim, S. S., Abbafati, C., Abbas, K. M., Abbasi, M., Abbasifard, M., Abbasi-Kangevari, M., Abbastabar, H., Abd-Allah, F., Abdelalim, A., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30925-9 · Cited by 19,358
Self-citation
Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial
Writing Group for the Women's Health Initiative Investigators (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.3.321 · Cited by 15,889
Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L., Jones, D. W., Materson, B. J., Oparil, S., Wright, J. T., et al. (2003) · Hypertension · doi:10.1161/01.hyp.0000107251.49515.c2 · Cited by 13,271
Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies
(2004) · The Lancet · doi:10.1016/s0140-6736(03)15268-3 · Cited by 12,717
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Yusuf, S., Hawken, S., Ôunpuu, S., Dans, T., Avezum, A., Lanas, F., McQueen, M., Budaj, A., Pais, P., Varigos, J., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17018-9 · Cited by 12,026
The Physical Activity Guidelines for Americans
Piercy, K. L., Troiano, R. P., Ballard, R. M., Carlson, S. A., Fulton, J. E., Galuska, D. A., George, S. M., & Olson, R. D. (2018) · JAMA · doi:10.1001/jama.2018.14854 · Cited by 9,755
Prevalence of Childhood and Adult Obesity in the United States, 2011-2012
Ogden, C. L., Carroll, M. D., Kit, B. K., & Flegal, K. M. (2014) · JAMA · doi:10.1001/jama.2014.732 · Cited by 8,072
IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045
Cho, N. H., Shaw, J. E., Karuranga, S., Huang, Y., da Rocha Fernandes, J. D., Ohlrogge, A. W., & Malanda, B. (2018) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2018.02.023 · Cited by 7,283

Show all 0 references

Research works printed but not linked: 2713

World Health Organization. International Statistical Classification of Diseases and Related Health Problems, 10th Revision. 2008 ed. Geneva, Switzerland: World Health Organization; 2009.
Anderson, RN, Rosenberg, HM. Age standardization of death rates: implementation of the year 2000 standard. Natl Vital Stat Rep. 1998;47:1–16, 20.
10.1016/S0140-6736(20)30752-2 · DOI · Paper page
10.1016/j.pcad.2015.05.003 · DOI
10.1016/j.ahj.2016.02.008 · DOI
10.1161/CIRCHEARTFAILURE.116.003682 · DOI
10.1016/j.amjmed.2015.03.027 · DOI
10.1371/journal.pone.0052771 · DOI
10.1161/JAHA.116.005180 · DOI
10.1093/ajh/hpz057 · DOI
10.1016/j.hlc.2016.02.007 · DOI
10.1016/j.ijcard.2015.03.051 · DOI
10.1016/j.mayocp.2016.01.019 · DOI · Paper page
10.1136/jech-2017-210396 · DOI
10.1016/j.ypmed.2016.12.017 · DOI
10.1111/ene.13056 · DOI
10.1111/1744-7917.12513 · DOI
10.1161/ATVBAHA.118.311821 · DOI
10.3390/ijerph16112028 · DOI
10.1016/j.ijcard.2018.06.037 · DOI
10.1177/0003319718813448 · DOI
10.1016/j.jacc.2010.11.041 · DOI · Paper page
10.1016/j.ijcard.2016.03.210 · DOI
10.1001/jama.2012.339 · DOI · Paper page
10.1161/STROKEAHA.111.000352 · DOI
10.1001/jama.2012.14312 · DOI
10.1016/j.ahj.2014.12.017 · DOI
10.1161/CIRCIMAGING.114.001851 · DOI
10.1371/journal.pone.0089317 · DOI
10.1016/j.psym.2013.06.016 · DOI
10.1161/JAHA.114.001322 · DOI
10.1161/JAHA.116.004105 · DOI
10.1136/bmjopen-2016-012486 · DOI
10.1016/j.rmed.2017.08.001 · DOI
10.1161/JAHA.114.001494 · DOI
10.1161/JAHA.117.007234 · DOI
10.1016/j.ijcard.2018.07.107 · DOI
10.1161/JAHA.117.007658 · DOI
10.1161/JAHA.117.008424 · DOI
10.1016/j.ypmed.2019.105890 · DOI
10.1136/bmjopen-2017-019434 · DOI · Paper page
10.1519/JSC.0000000000003052 · DOI
10.1016/j.maturitas.2018.11.015 · DOI
10.1016/j.pmedr.2019.100922 · DOI
10.1016/j.ijcard.2015.05.007 · DOI
10.1016/j.healthplace.2017.01.005 · DOI
10.1016/j.amepre.2015.03.034 · DOI
10.1016/j.mayocp.2016.12.026 · DOI · Paper page
10.1001/jamanetworkopen.2019.4758 · DOI
10.1161/CIRCULATIONAHA.111.081083 · DOI · Paper page
10.1161/JAHA.116.003192 · DOI
10.1007/s00125-018-4792-y · DOI
10.1161/JAHA.116.005008 · DOI
10.1016/j.amepre.2015.07.039 · DOI
10.1161/CIRCULATIONAHA.112.001183 · DOI
10.1016/S0140-6736(20)30752-2 · DOI · Paper page
10.1016/S0140-6736(20)30925-9 · DOI · Paper page
10.1056/NEJMsa1211127 · DOI · Paper page
10.15585/mmwr.mm6806e1 · DOI
10.15585/mmwr.mm6845a2 · DOI
10.1056/NEJMp1805758 · DOI
10.15585/mmwr.ss6812a1 · DOI · Paper page
Drake, P, Driscoll, AK, Mathews, TJ. Cigarette smoking during pregnancy: United States, 2016. NCHS Data Brief. 20181–8.
10.1001/jamanetworkopen.2018.7794 · DOI
10.15585/mmwr.mm6744a2 · DOI
US Department of Health and Human Services. The Health Consequences of Smoking-50 Years of Progress: A Report of the Surgeon GeneralUS Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2014.
10.15585/mmwr.mm6544a2 · DOI
10.1016/j.amjmed.2019.12.020 · DOI
US Department of Health and Human Services. How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Surgeon GeneralUS Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2010.
10.1186/s12889-015-1617-5 · DOI
10.1093/cid/civ013 · DOI
10.1161/STR.0000000000000046 · DOI · Paper page
10.1161/STROKEAHA.113.002342 · DOI
10.1177/2047487318806658 · DOI
10.1016/j.amjcard.2019.03.015 · DOI
10.3109/08958378.2016.1171934 · DOI
10.1093/aje/kwq191 · DOI
10.1161/CIR.0000000000000107 · DOI
10.1007/s12170-016-0505-6 · DOI
10.1016/j.tcm.2019.04.006 · DOI
10.1016/j.amepre.2018.05.004 · DOI
10.1016/j.amjmed.2019.02.016 · DOI
10.1016/j.biopsych.2018.11.024 · DOI
10.1038/s41380-018-0313-0 · DOI
10.1161/CIRCULATIONAHA.116.022069 · DOI
10.1136/tobaccocontrol-2014-052207 · DOI · Paper page
10.1093/ntr/ntz123 · DOI
10.1056/NEJMp1603294 · DOI
10.15585/mmwr.mm6828a1 · DOI
10.1161/JAHA.118.011307 · DOI
10.1001/jamanetworkopen.2019.4585 · DOI
10.1016/j.ahj.2019.03.019 · DOI
10.1001/jama.2019.10298 · DOI
10.1016/j.amepre.2008.04.009 · DOI · Paper page
10.1161/CIR.0000000000000678 · DOI · Paper page
10.1161/CIRCULATIONAHA.115.019634 · DOI
10.1016/S0140-6736(16)30272-0 · DOI · Paper page
10.1001/jamainternmed.2014.8313 · DOI
Centers for Disease Control and Prevention. Quitting smoking among adults–United States, 2001-2010. MMWR Morb Mortal Wkly Rep. 2011;60:1513–1519.
10.1016/j.amepre.2014.10.011 · DOI
10.1161/JAHA.113.000740 · DOI
10.1056/NEJMoa1808779 · DOI
10.1136/tobaccocontrol-2017-054108 · DOI
10.1001/jama.2018.0158 · DOI
10.1136/bmj.h1551 · DOI
10.1007/s10654-015-0031-8 · DOI
10.1161/CIR.0000000000000669 · DOI
10.7326/M18-1826 · DOI
Arrazola, RA, Singh, T, Corey, CG, Husten, CG, Neff, LJ, Apelberg, BJ, Bunnell, RE, Choiniere, CJ, King, BA, Cox, S, et al; Centers for Disease Control and Prevention (CDC). Tobacco use among middle and high school students–United States, 2011-2014. MMWR Morb Mortal Wkly Rep. 2015;64:381–385.
10.15585/mmwr.mm6710a3 · DOI · Paper page
10.1136/tobaccocontrol-2014-051670 · DOI
10.7326/M17-3440 · DOI
10.1093/ntr/ntz021 · DOI
Eaton, DL, Kwan, LY, Stratton, K, eds. Public Health Consequences of E-CigarettesWashington, DC: National Academies Press; 2018.
10.1093/ntr/nty089 · DOI
10.7326/M16-1107 · DOI · Paper page
10.7759/cureus.7088 · DOI
10.1001/jamanetworkopen.2019.16800 · DOI
10.1186/s12890-019-0950-3 · DOI
10.1016/j.amepre.2019.10.014 · DOI
10.1161/STROKEAHA.116.014099 · DOI
10.1016/j.ijcard.2015.07.011 · DOI
10.1371/journal.pone.0147848 · DOI
10.1016/j.jacc.2019.07.060 · DOI
10.1136/hrt.2010.199026 · DOI
Centers for Disease Control and Prevention. Vital signs: disparities in nonsmokers’ exposure to secondhand smoke–United States, 1999-2012. MMWR Morb Mortal Wkly Rep. 2015;64:103–108.
10.1016/j.amepre.2014.10.012 · DOI
10.1016/S0140-6736(18)32225-6 · DOI · Paper page
10.1016/S0140-6736(20)30752-2 · DOI · Paper page
10.15585/mmwr.mm6738a7 · DOI
10.1161/CIRCULATIONAHA.109.192703 · DOI · Paper page
US Department of Health and Human Services. Physical Activity Guidelines for Americans. 2nd ed. Department of Health and Human Services; 2018.
10.15585/mmwr.ss6708a1 · DOI · Paper page
10.1161/01.cir.0000435708.67487.da · DOI · Paper page
10.1161/CIR.0000000000000678 · DOI · Paper page
2018 Physical Activity Guidelines Advisory Committee. 2018 Physical Activity Guidelines Advisory Committee Scientific ReportUS Department of Health and Human Services; 2018.
10.1161/STR.0000000000000148 · DOI · Paper page
10.1001/jamaneurol.2017.1658 · DOI · Paper page
10.1016/j.amepre.2018.07.036 · DOI
10.1161/CIR.0b013e31827ee100 · DOI
10.1161/CIR.0000000000000461 · DOI · Paper page
10.1016/j.pcad.2014.09.008 · DOI
10.2471/BLT.18.213728 · DOI
10.1371/journal.pone.0115915 · DOI
Gahche, J, Fakhouri, T, Carroll, DD, Burt, VL, Wang, CY, Fulton, JE. Cardiorespiratory fitness levels among U.S. youth aged 12-15 years: United States, 1999-2004 and 2012. NCHS Data Brief. 20141–8.
10.1016/j.ypmed.2018.10.016 · DOI
Rideout, V. The Common Sense Census: Media Use by Kids Age Zero to EightCommon Sense Media; 2017. Accessed March 9, 2020. https://www.vjrconsulting.com/featured/2018/9/16/the-common-sense-census-media-use-by-kids-age-zero-to-eight-2017.
10.1542/peds.2016-2592 · DOI · Paper page
10.1016/j.amepre.2010.12.016 · DOI · Paper page
10.5888/pcd11.140189 · DOI
10.1186/s12966-017-0642-4 · DOI
The Nielsen Total Audience Report. 2019. Accessed October 20, 2020. https://www.nielsen.com/us/en/insights/article/2020/the-nielsen-total-audience-report-hub/.
10.1136/bjsports-2018-100056 · DOI · Paper page
10.1097/AOG.0000000000001214 · DOI
10.1249/MSS.0000000000001941 · DOI
10.1136/bjsports-2018-099399 · DOI
10.1016/j.amepre.2016.05.023 · DOI
10.1016/j.amepre.2018.07.008 · DOI
10.15585/mmwr.ss6407a1 · DOI
10.1001/jama.2018.17797 · DOI
10.1001/jama.2019.3636 · DOI
10.1016/j.amepre.2018.05.027 · DOI
Shifts in Viewing: The Cross-Platform Report: September 2014Nielsen Company; 2014.
10.1016/j.ypmed.2018.02.011 · DOI
10.1038/s41366-018-0120-3 · DOI · Paper page
10.1161/CIR.0000000000000440 · DOI · Paper page
10.1249/MSS.0000000000001607 · DOI
US Department of Health and Human Services. Step It Up! The Surgeon General’s Call to Action to Promote Walking and Walkable CommunitiesUS Dept of Health and Human Services, Office of the Surgeon General; 2015.
10.1001/jama.2016.5898 · DOI
10.1289/ehp.1510425 · DOI
Centers for Disease Control and Prevention and SHAPE America–Society of Health and Physical Educators. . Strategies for Recess in SchoolsCenters for Disease Control and Prevention, US Department of Health and Human Services; 2017.
10.1016/j.amepre.2015.06.022 · DOI
10.1249/MSS.0000000000001328 · DOI
10.5888/pcd18.170354 · DOI · Paper page
10.1136/bjsports-2014-094306 · DOI · Paper page
10.1001/jamainternmed.2015.0533 · DOI · Paper page
10.1161/JAHA.117.007677 · DOI
10.1007/s40279-018-1023-0 · DOI
10.1136/bmj.j1456 · DOI
10.1136/bjsports-2017-098540 · DOI · Paper page
10.1016/S0140-6736(16)30370-1 · DOI · Paper page
10.1093/aje/kwy125 · DOI
10.1016/j.amepre.2018.12.006 · DOI
10.1249/MSS.0000000000000885 · DOI
10.1249/MSS.0000000000001932 · DOI
10.1161/CIRCOUTCOMES.113.000531 · DOI
10.1016/j.ypmed.2019.105799 · DOI
10.1093/eurheartj/ehw249 · DOI
10.1038/ijo.2016.210 · DOI
10.3945/ajcn.116.150540 · DOI
10.1249/MSS.0000000000001310 · DOI
10.1080/02640414.2016.1260150 · DOI
10.1161/JAHA.116.004413 · DOI
10.1177/2047487314562741 · DOI
10.1161/HYPERTENSIONAHA.116.08994 · DOI
10.1249/MSS.0000000000001484 · DOI
Zwald, ML, Akinbami, LJ, Fakhouri, TH, Fryar, CD. Prevalence of low high-density lipoprotein cholesterol among adults, by physical activity: United States, 2011-2014. NCHS Data Brief. 20171–8.
10.1161/CIRCULATIONAHA.115.016938 · DOI
10.1161/CIRCULATIONAHA.116.026858 · DOI
10.1111/aogs.13151 · DOI

200 of 2713 shown

Sorted by citations

Items 201–300 of 1,044

Mitochondria transplantation alleviates cardiomyocytes apoptosis through inhibiting AMPKα‐mTOR mediated excessive autophagy
Jin, N., Zhang, M., Zhou, L., Jin, S., Cheng, H., Li, X., Shi, Y., Xiang, T., Zhang, Z., Liu, Z., et al. (2024) · The FASEB Journal · doi:10.1096/fj.202400375r · Cited by 29
Sex Differences in Receipt of Bystander Cardiopulmonary Resuscitation Considering Neighborhood Racial and Ethnic Composition
Blewer, A., Starks, M., Malta-Hansen, C., Sasson, C., Ong, M., Al-Araji, R., McNally, B. F., & Viera, A. J. (2024) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.123.031113 · Cited by 24
Fall Risk Assessment in Stroke Survivors: A Machine Learning Model Using Detailed Motion Data from Common Clinical Tests and Motor-Cognitive Dual-Tasking
Abdollahi, M., Rashedi, E., Jahangiri, S., Kuber, P. M., Azadeh-Fard, N., & Dombovy, M. (2024) · Italian National Conference on Sensors · doi:10.3390/s24030812 · Cited by 24
“The US alone sees 800,000 stroke cases (~75% experiencing first time) every year [1].”
Background
SMYD1a protects the heart from ischemic injury by regulating OPA1-mediated cristae remodeling and supercomplex formation
Szulik, M. W., Valdez, S., Walsh, M., Davis, K., Bia, R. D., Horiuchi, E., O’Very, S., Laxman, A. K., Nicolova, L., Eberhardt, D., et al. (2023) · Basic Research in Cardiology · doi:10.1007/s00395-023-00991-6 · Cited by 26
BRG1 alleviates microglial activation by promoting the KEAP1-NRF2/HO-1 signaling pathway and minimizing oxidative damage in cerebral ischemia-reperfusion.
Guo, K., Shang, Y.-X., Wang, Z., Li, Y., Chen, J.-L., Zhu, B.-F., Zhang, D., & Chen, J.-R. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110201 · Cited by 24
Cardiac cells and mesenchymal stem cells derived extracellular vesicles: a potential therapeutic strategy for myocardial infarction
Qin, D., Wang, X., Pu, J., & Hu, H. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1493290 · Cited by 26
Advancements in Cardiovascular Disease Research Affected by Smoking
Fu, M., Mei, A., Min, X., Yang, H., Wu, W., Zhong, J., Li, C., & Chen, J. (2024) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2508298 · Cited by 26
“Female smokers have a 25% higher risk of ischemic heart disease than male smokers, possibly due to the influence of smoking on menopause and its anti-estrogenic effects, with long-term smoking having a greater impact on atherosclerosis in women than in men [77].”
Background
Chapter 3: Clinical Trials of Sodium-Glucose Co-Transporter-2 Inhibitors for Treatment of Heart Failure
Greene, S. J., Butler, J., & Kosiborod, M. (2024) · The American Journal of Medicine · doi:10.1016/j.amjmed.2023.04.019 · Cited by 28
Challenges & barriers for real-time integration of drones in emergency cardiac care: Lessons from the United States, Sweden, & Canada
Zègre-Hemsey, J., Cheskes, S., Johnson, A., Rosamond, W., Cunningham, C. J., Arnold, E., Schierbeck, S., & Claesson, A. (2024) · Resuscitation Plus · doi:10.1016/j.resplu.2024.100554 · Cited by 23
Economic Evaluations of Digital Health Interventions for Patients With Heart Failure: Systematic Review
Zakiyah, N., Marulin, D., Alfaqeeh, M., Puspitasari, I. M., Lestari, K., Lim, K. K., & Fox-Rushby, J. A. (2024) · Journal of Medical Internet Research · doi:10.2196/53500 · Cited by 37
“This is attributed to the improved survival rates after an HF diagnosis and the aging population [1,6,7].”
From diabetic hyperglycemia to cerebrovascular Damage: A narrative review
Machado, R. S., Mathias, K., Joaquim, L. D. S., de Quadros, R. W., Petronilho, F. C., & Rezin, G. T. (2023) · Brain Research · doi:10.1016/j.brainres.2023.148611 · Cited by 25
Predictive metabolites for incident myocardial infarction: a two-step meta-analysis of individual patient data from six cohorts comprising 7897 individuals from the COnsortium of METabolomics Studies
Nogal, A., Alkis, T., Lee, Y., Kifer, D., Hu, J., Murphy, R. A., Huang, Z., Wang-Sattler, R., Kastenmüler, G., Linkohr, B., et al. (2023) · Cardiovascular Research · doi:10.1093/cvr/cvad147 · Cited by 23
Association of Cardiovascular Risks in Rheumatoid Arthritis Patients: Management, Treatment and Future Perspectives
Johri, N., Varshney, S., Gandha, S., Maurya, A., Mittal, P., Jangra, S., & Saraf, A. (2023) · Health Sciences Review · doi:10.1016/j.hsr.2023.100108 · Cited by 23
Cutting-edge advances in modeling the blood–brain barrier and tools for its reversible permeabilization for enhanced drug delivery into the brain
Sharma, A., Fernandes, D. C., Reis, R. L., Gołubczyk, D., Neumann, S., Łukomska, B., Janowski, M., Kortylewski, M., Walczak, P., Oliveira, J. M., et al. (2023) · Cell & Bioscience · doi:10.1186/s13578-023-01079-3 · Cited by 26
“Brain ischemia is one of the two main concerns regarding BBB disruptions, particularly considering brain-related vascular problems are a main health concern worldwide [43].”
Background
Motor Learning Following Stroke
Winterbottom, L., & Nilsen, D. M. (2023) · Physical Medicine and Rehabilitation Clinics of North America · doi:10.1016/j.pmr.2023.06.004 · Cited by 32
Design, Modeling and Experiments of a Variable Stiffness Soft Robotic Glove for Stroke Patients With Clenched Fist Deformity
Li, X., Hao, Y., Zhang, J., Wang, C., Dai, L., & Zhang, J. (2023) · IEEE Robotics and Automation Letters · doi:10.1109/lra.2023.3279613 · Cited by 34
“In the United States, approximately 795000 people suffer a stroke yearly [1].”
Background
Diagnostic Strategies for the Assessment of Suspected Stable Coronary Artery Disease
Zito, A., Galli, M., Biondi‐Zoccai, G., Abbate, A., Douglas, P. S., Princi, G., D’Amario, D., Aurigemma, C., Romagnoli, E., Trani, C., et al. (2023) · Annals of Internal Medicine · doi:10.7326/m23-0231 · Cited by 26
Etiologies and Predictors of 30-Day Readmission in Heart Failure: An Updated Analysis
Jain, A., Arora, S., Patel, V., Raval, M., Modi, K., Arora, N., Desai, R., Bozorgnia, B., & Bonita, R. (2023) · International Journal of Heart Failure · doi:10.36628/ijhf.2023.0015 · Cited by 23
Bushen Huoxue Yiqi formula alleviates cardiac fibrosis in ischemic heart failure through SIRT1/Notch1 pathway-mediated EndMT.
Chen, C., Wang, J., Hou, C.-Z., Lian, W.-J., Zhu, X., Hu, J.-Y., & Liu, C. (2024) · Phytomedicine · doi:10.1016/j.phymed.2024.156252 · Cited by 22
Lessons on Health Literacy and Communication in Post-Stroke Rehabilitation:
Cook, C. V., & Pompon, R. H. (2023) · Delaware journal of public health · doi:10.32481/djph.2023.08.010 · Cited by 22
A Narrative Review of Non-Pharmacological Strategies for Managing Sarcopenia in Older Adults with Cardiovascular and Metabolic Diseases
Ispoglou, T., Wilson, O. J., McCullough, D., Aldrich, L., Ferentinos, P. P., Lyall, G. K., Stavropoulos‐Kalinoglou, A., Duckworth, L. C., Brown, M. A., Sutton, L., et al. (2023) · Biology · doi:10.3390/biology12070892 · Cited by 24
“CVD and MDs are often caused by a combination of genetic, lifestyle and environmental factors [6,7] with older adults being more susceptible to CVD and death [8].”
Epidemiologic trends and risk factors associated with the decline in mortality from coronary heart disease in the United States, 1990-2019
Ananth, C. V., Rutherford, C. G., Rosenfeld, E. B., Brandt, J. S., Graham, H. L., Kostis, W. J., & Keyes, K. M. (2023) · American Heart Journal · doi:10.1016/j.ahj.2023.05.006 · Cited by 23
4D Thermo-Responsive Smart hiPSC-CM Cardiac Construct for Myocardial Cell Therapy
Hann, S.-Y., Cui, H., Esworthy, T. J., & Zhang, L. G. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s402855 · Cited by 30
Integrative microbiomics, proteomics and lipidomics studies unraveled the preventive mechanism of Shouhui Tongbian Capsules on cerebral ischemic stroke injury
Wei, F., Zhou, J., Pan, L., Shen, M., Niu, D., Zeng, Z., Cheng, G., Yao, J., Zhang, G., & Sun, C. (2024) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2024.118874 · Cited by 23
Tackling exosome and nuclear receptor interaction: an emerging paradigm in the treatment of chronic diseases
Aswani, B. S., Hegde, M., Vishwa, R., Alqahtani, M. S., Abbas, M., Almubarak, H. A., Sethi, G., & Kunnumakkara, A. B. (2024) · Military Medical Research · doi:10.1186/s40779-024-00564-1 · Cited by 17
“CVDs, particularly coronary artery disease (CAD), continue to be the leading global cause of mortality [183– 185].”
Background
Dyslipidemia in American Indian Adolescents and Young Adults: Strong Heart Family Study
Reese, J. A., Roman, M. J., Deen, J. F., Ali, T., Cole, S. A., Devereux, R. B., Fretts, A. M., Howard, W. J., Lee, E. T., Malloy, K., et al. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.031741 · Cited by 24
Prediction of outcomes after cardiac arrest by a generative artificial intelligence model
Amacher, S. A., Arpagaus, A., Sahmer, C., Becker, C., Groß, S., Urben, T., Tisljar, K., Sutter, R., Marsch, S. C. U., & Hunziker, S. (2024) · Resuscitation Plus · doi:10.1016/j.resplu.2024.100587 · Cited by 26
Implications of Bias in Artificial Intelligence: Considerations for Cardiovascular Imaging
van Assen, M., Beecy, A., Gershon, G., Newsome, J. M., Trivedi, H., & Gichoya, J. W. (2024) · Current Atherosclerosis Reports · doi:10.1007/s11883-024-01190-x · Cited by 25
“The prevalence and outcomes of CVD demonstrate significant disparities across gender and race [1, 16, 17].”
Chapter 1: The Burden of Heart Failure
Pratley, R. E., Guan, X., Moro, R. J., & do Lago, R. (2024) · The American Journal of Medicine · doi:10.1016/j.amjmed.2023.04.018 · Cited by 26
β-Hydroxybutyrate Administered at Reperfusion Reduces Infarct Size and Preserves Cardiac Function by Improving Mitochondrial Function Through Autophagy
Chu, Y., Hua, Y., He, L., He, J. H., Chen, Y., Yang, J., Mahmoud, I., Zeng, F., Zeng, X., Benavides, G. A., et al. (2023) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2023.11.001 · Cited by 23
Evaluation of cholesterol transformation abilities and probiotic properties of Bacteroides dorei YGMCC0564
He, Z., Wang, T., Zhang, S., Shi, K., Wang, F., Li, Y., Lin, C., & Chen, J. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1279996 · Cited by 22
“CVD is a major global health issue and one of the leading causes of death worldwide (Virani et al., 2021).”
Background
Recent advances in soluble decellularized extracellular matrix for heart tissue engineering and organ modeling
Kafili, G., Kabir, H., Kandeloos, A. J., Golafshan, E., Ghasemi, S., Mashayekhan, S., & Taebnia, N. (2023) · Journal of Biomaterials Applications · doi:10.1177/08853282231207216 · Cited by 20
Role of microRNA-34a in blood–brain barrier permeability and mitochondrial function in ischemic stroke
Payne, C. T., Tabassum, S., Wu, S., Hu, H., Gusdon, A. M., Choi, H. A., & Ren, X. S. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1278334 · Cited by 23
Vascular smooth muscle cells enhance immune/vascular interplay in a 3-cell model of vascular inflammation
Wiejak, J., Murphy, F. A., Maffia, P., & Yarwood, S. J. (2023) · Scientific Reports · doi:10.1038/s41598-023-43221-8 · Cited by 24
Bellidifolin ameliorates isoprenaline-induced cardiac hypertrophy by the Nox4/ROS signalling pathway through inhibiting BRD4
Zhou, D., Liu, W., Zhang, J., Dong, Y., Wu, J., Zhang, Y., Dai, C., Zhang, T., Yang, G.-S., Zhang, Y., et al. (2023) · Cell Death Discovery · doi:10.1038/s41420-023-01563-2 · Cited by 21
“INTRODUCTION Pathological cardiac hypertrophy is usually induced by pressure overload and leads to heart failure, which is a prevalent cause of morbidity and mortality worldwide [1, 2].”
Background
J-shaped association between LDL cholesterol and cardiovascular events: A longitudinal primary prevention cohort of over 2.4 million people nationwide
Park, C. S., Yang, H., Han, K., Lee, H., Kang, J., Han, J., Park, K. W., Kang, H., Koo, B., & Kim, H.-S. (2023) · Journal of Advanced Research · doi:10.1016/j.jare.2023.05.003 · Cited by 23
“However, it remains largely responsible for morbidity and mortality [1], suggesting the need for better risk stratiﬁcation and tailored management.”
Background
Gene therapy in cardiac and vascular diseases: a review of approaches to treat genetic and common cardiovascular diseases with novel gene-based therapeutics
Musolino, P. L., Rosser, S. J., Brittan, M., Newby, D. E., Berry, C., Riley, P. R., Giacca, M., Hajjar, R. J., & Baker, A. H. (2025) · Cardiovascular Research · doi:10.1093/cvr/cvaf109 · Cited by 23
Kinesiophobia in patients with coronary heart disease: a Rodgers’ evolutionary concept analysis
Zhang, M.-J., Liu, S., Xiong, X.-Y., Liu, M.-D., & Xiang, Q. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1499962 · Cited by 20
“The World Heart Association projects global cardiovascular costs to rise from $863 billion in 2010 to $1,044 billion by 2030 (Virani et al., 2021).”
Combination of an LDH-based platform with microRNA for the treatment of myocardial Ischemia-Reperfusion injury by pyroptosis inhibition via the CaSR/PLCγ1/IP3R pathway
Wu, C., Wang, H., Niu, J., Wei, B., Gao, Y., Li, Y., Wang, H., Lyu, Q., Jing, G., Wang, H., et al. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.160833 · Cited by 18
Biomimetic nanoplatform treats myocardial ischemia/reperfusion injury by synergistically promoting angiogenesis and inhibiting inflammation.
Lei, F., Zhang, J., Deng, Y., Wang, X., Tang, J., Tian, J., Wan, Y., Wang, L., Zhou, X., Zhang, Y., et al. (2024) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/j.colsurfb.2024.114159 · Cited by 20
A machine learning model to predict heart failure readmission: toward optimal feature set
Jahangiri, S., Abdollahi, M., Rashedi, E., & Azadeh-Fard, N. (2024) · Frontiers Artif. Intell. · doi:10.3389/frai.2024.1363226 · Cited by 20
Acupuncture for ischemic stroke: where are we now?
Zhu, W., Jia, Q., Ferreira, A., Jiang, H.-L., Zhang, J.-Y., Li, B.-X., Zhang, M.-L., Zhuo, B., Lyu, Y., Chen, J.-J., et al. (2024) · Acupuncture & Herbal Medicine · doi:10.1097/hm9.0000000000000094 · Cited by 20
“It ranks fifth among the causes of death after heart disease, cancer, chronic lower respiratory disease, and accidental injury [3] .”
Background
Effect of skipping breakfast on cardiovascular risk factors: a grade-assessed systematic review and meta-analysis of randomized controlled trials and prospective cohort studies
Yu, J., Xia, J., Xu, D., Wang, Y., Yin, S., Lü, Y., Xia, H., Wang, S., & Sun, G. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1256899 · Cited by 21
Local decorin delivery via hyaluronic acid microrods improves cardiac performance, ventricular remodeling after myocardial infarction
Mohindra, P., Zhong, J. X., Fang, Q.-Z., Cuylear, D., Huynh, C., Qiu, H., Gao, D., Kharbikar, B. N., Huang, X., Springer, M., et al. (2023) · npj Regenerative Medicine · doi:10.1038/s41536-023-00336-w · Cited by 20
“The prognosis for HF is poor, with an estimated mortality rate of ~50% within 5 years of the diagnosis 1 .”
Influential
Effects of Metformin on Ischemia/Reperfusion Injury: New Evidence and Mechanisms
Osorio-Llanes, E., Villamizar-Villamizar, W., Ospino-Guerra, M. C., Díaz-Ariza, L. A., Castiblanco-Arroyave, S. C., Medrano, L., Mengual, D., Belón, R., Castellar-López, J., Sepulveda, Y., et al. (2023) · Pharmaceuticals · doi:10.3390/ph16081121 · Cited by 20
“and it is predicted that it will increase to more than USD 177 billion by the year 2040 [47].”
Background
Three-Dimensional Bioprinting in Cardiovascular Disease: Current Status and Future Directions
Sun, Z.-H., Zhao, J., Leung, E., Flandes-Iparraguirre, M., Vernon, M. J., Silberstein, J., De-Juan-Pardo, E., & Jansen, S. (2023) · Biomolecules · doi:10.3390/biom13081180 · Cited by 20
Study on the mechanism of action of colchicine in the treatment of coronary artery disease based on network pharmacology and molecular docking technology
Yu, Y., Zhou, M., Long, X., Yin, S., Hu, G., Yang, X., Jian, W., & Yu, R. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1147360 · Cited by 24
“, 2022) and is a major source of global cardiovascular disease morbidity, mortality, and economic burden on health (Virani et al., 2021).”
Background
"Do-not-resuscitate" preferences of the general Swiss population: Results from a national survey.
Gross, S., Amacher, S., Rochowski, A., Reiser, S., Becker, C., Beck, K., Blatter, R., Emsden, C., Nkoulou, C., Sutter, R., et al. (2023) · Resuscitation Plus · doi:10.1016/j.resplu.2023.100383 · Cited by 20
Plasma-derived exosomal let-7c-5p, miR-335–3p, and miR-652–3p as potential diagnostic biomarkers for stable coronary artery disease
Han, J., Cui, X.-G., Yuan, T., Yang, Z., Liu, Y., Ren, Y., Wu, C.-X., & Bian, Y. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1161612 · Cited by 20
“More importantly, if SCAD cannot be timely and effectively controlled, it will develop to ACS, leading to the increased risk of more severe clinical syndrome and death of patients (Virani et al., 2021).”
Background
Cardiac Rehabilitation in the Modern Era: Evidence, Equity, and Evolving Delivery Models Across the Cardiovascular Spectrum
Mueller, A. S., & Kim, S. M. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14155573 · Cited by 28
“Cardiovascular disease remains the leading cause of death in the United States, with over 18 million adults currently living with some form of heart disease [1].”
Myocardial infarction, stroke and arterial stenosis: time to reassess a major misunderstanding
Saba, L., & Libby, P. (2025) · Nature Reviews Cardiology · doi:10.1038/s41569-025-01186-3 · Cited by 19
“This complexity rationalizes the categorization of many strokes as ‘embolic strokes of undetermined source’ 30,31 .”
Association of cardiometabolic index with all-cause and cardiovascular mortality among middle-aged and elderly populations
Zhu, M.-Y., Jin, H., Yin, Y.-J., Xu, Y., & Zhu, Y.-G. (2025) · Scientific Reports · doi:10.1038/s41598-024-83914-2 · Cited by 19
In vitro vascularization improves in vivo functionality of human engineered cardiac tissues
Li, H., Shadrin, I. Y., Helfer, A., Heman, K. L., Rao, L., Curtis, C., Palmer, G. M., & Bursac, N. (2024) · Acta Biomaterialia · doi:10.1016/j.actbio.2024.11.014 · Cited by 18
Clinical and subclinical acute brain injury caused by invasive cardiovascular procedures
Lenarczyk, R., Proietti, M., Scheitz, J. F., Shah, D., Siebert, E., Gorog, D. A., Kowalczyk, J. P., Bonaros, N. E., Ntaios, G., Doehner, W., et al. (2024) · Nature Reviews Cardiology · doi:10.1038/s41569-024-01076-0 · Cited by 23
“An estimated 1.5 million patients undergo PCI and coronary angiography procedures annually in the USA 22,41,42 .”
Influential
Triglyceride–glucose index and prognosis in individuals afflicted with heart failure and chronic kidney disease
Chen, Y., Li, S.-M., Yang, K., Wu, B.-Y., Xie, D., Peng, C.-Q., & Lai, W. (2024) · ESC Heart Failure · doi:10.1002/ehf2.14898 · Cited by 19
“15 Notably, CKD often coexists with HF, with reported prevalences reaching 53% in those experiencing acute HF and 42% in chronic cases.”
Background
Association of Lipoprotein (a) and Standard Modifiable Cardiovascular Risk Factors With Incident Myocardial Infarction: The Mass General Brigham Lp(a) Registry
Shiyovich, A., Berman, A. N., Besser, S. A., Biery, D. W., Kaur, G., Divakaran, S., Singh, A., Huck, D. M., Weber, B., Plutzky, J., et al. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.034493 · Cited by 30
Ubiquitous regulation of cerebrovascular diseases by ubiquitin‐modifying enzymes
Huang, J., Zhu, Z., Schlüter, D., Lambertsen, K. L., Song, W., & Wang, X. (2024) · Clinical and Translational Medicine · doi:10.1002/ctm2.1719 · Cited by 18
“116,163 Recent studies have elucidated the pivotal roles of UMEs in CVDs, shedding light on the mechanism and therapy of these medical emergencies.”
Background
Atherectomy - The Options, the Evidence, and When Should it be Used.
Pinto, P., & Chaar, C. O. (2024) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2023.12.104 · Cited by 19
The relationship between caregiver contribution to self-care and patient quality of life in heart failure: A longitudinal mediation analysis
Caggianelli, G., Alivernini, F., Chirico, A., Iovino, P., Lucidi, F., Uchmanowicz, I., Rasero, L., Alvaro, R., & Vellone, E. (2024) · PLoS ONE · doi:10.1371/journal.pone.0300101 · Cited by 19
“Notwithstanding, the prevalence of HF is projected to rise as a result of an ageing population, improved risk factors management and rising survival rates [4, 5].”
Background
Threats of per- and poly-fluoroalkyl pollutants to susceptible populations
Mao, X., Liu, Y., Wei, Y., Li, X., Liu, Y., Su, G., Wang, X., Jia, J., & Yan, B. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.171188 · Cited by 21
Res-BiANet: A Hybrid Deep Learning Model for Arrhythmia Detection Based on PPG Signal
Wu, Y., Tang, Q., Zhan, W., Li, S., & Chen, Z. (2024) · Electronics · doi:10.3390/electronics13030665 · Cited by 25
Mesenchymal stem cells as future treatment for cardiovascular regeneration and its challenges
Seow, K. S., & Ling, A. P. K. (2024) · Annals of Translational Medicine · doi:10.21037/atm-23-1936 · Cited by 21
“It is an ever-growing healthcare problem accounting for a total of 32% of global deaths and taking approximately 17.9 million of lives annually (3).”
BackgroundInfluential
Vagus nerve stimulation as immunomodulatory therapy for stroke: A comprehensive review
Jelinek, M., Lipková, J., & Ďuriš, K. (2023) · Experimental Neurology · doi:10.1016/j.expneurol.2023.114628 · Cited by 23
“It is also a major cause of premature death as it represents the second highest cause of death worldwide with 6.6 million deaths every year (Virani et al., 2021; Kim et al., 2020).”
Influential
Association Between Hypertension and Diabetes Control and COVID‐19 Severity: National Patient‐Centered Clinical Research Network, United States, March 2020 to February 2022
Jackson, S. L., Woodruff, R., Nagavedu, K., Fearrington, J. A., Rolka, D. B., Twentyman, E., Carton, T. W., Puro, J., Denson, J., Kappelman, M., et al. (2023) · Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease · doi:10.1161/jaha.122.030240 · Cited by 19
Frailty Status Modifies the Efficacy of ICD Therapy for Primary Prevention Among Patients With HF.
Segar, M. W., Keshvani, N., Singh, S., Patel, L., Parsa, S., Betts, T., Reeves, G. R., Mentz, R., Forman, D., Razavi, M., et al. (2023) · JACC. Heart failure · doi:10.1016/j.jchf.2023.06.009 · Cited by 19
Anti-Inflammatory, Antioxidant, Metabolic and Gut Microbiota Modulation Activities of Probiotic in Cardiac Remodeling Condition: Evidence from Systematic Study and Meta-Analysis of Randomized Controlled Trials
Taslim, N. A., Yusuf, M. F. R. H., Ambari, A. M., Puling, I. M. D. R., Ibrahim, F. Z., Hardinsyah, H., Kurniawan, R., Gunawan, W. B., Mayulu, N., Joseph, V. F. F., et al. (2023) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-023-10105-2 · Cited by 25
Health Professional- and Volunteer-partnered Self-management Support (COMBO-KEY) to Promote Self-efficacy and Self-management Behaviors in People with Stroke: A Randomized Controlled Trial
Lo, S., Chau, J., Choi, K.-C., Wong, R., Kwan, J., & Iu, I. H. L. (2023) · Annals of Behavioral Medicine · doi:10.1093/abm/kaad028 · Cited by 19
Trends in unhealthy lifestyle factors in US NHANES respondents with cardiovascular disease for the period between 1999 and 2018
Liang, Y., Liu, F.-Y., Yin, H., Shi, X., Chen, Y., Wang, H., Wang, Y., Bai, B.-Q., Liu, Y.-T., Liu, Q., et al. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1169036 · Cited by 19
Mitral Regurgitation in Female Patients: Sex Differences and Disparities
Ocher, R. A., May, M., Labin, J. E., Shah, J., Horwich, T. B., Watson, K. E., Yang, E., & Calfon-Press, M. (2023) · Journal of the Society for Cardiovascular Angiography & Interventions · doi:10.1016/j.jscai.2023.101032 · Cited by 19
“3,5 This Swedish analysis revealed that MR made up 24.2% of valvular disease diagnoses, 3,5 but, world-wide, MR represents the most common valvular disease.”
BackgroundInfluential
Malnutrition and poststroke depression in patients with ischemic stroke.
Gu, M.-M., Wang, J.-J., Xiao, L.-L., Chen, X.-L., Wang, M., Huang, Q., Zhou, J.-S., & Sun, W. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.04.104 · Cited by 19
Correlation Between Coronary and Retinal Microangiopathy in Patients With STEMI
Sideri, A., Kanakis, M., Katsimpris, A., Karamaounas, A., Brouzas, D., Petrou, P., Papakonstaninou, E., Droutsas, K., Kandarakis, S., Giannopoulos, G., et al. (2023) · Translational Vision Science & Technology · doi:10.1167/tvst.12.5.8 · Cited by 19
Cardiovascular Risk Factor Disparities in Adult Survivors of Childhood Cancer Compared With the General Population
Noyd, D., Liu, Q., Yasui, Y., Chow, E. J., Bhatia, S., Nathan, P., Landstrom, A., Tonorezos, E., Casillas, J., Berkman, A., et al. (2023) · JACC CardioOncology · doi:10.1016/j.jaccao.2023.01.011 · Cited by 19
Sodium glucose co-transporter inhibitors and heart failure outcomes across different patient populations
Butler, J., Anker, S. D., Filippatos, G., Usman, M. S., Ferreira, J. P., Zannad, F., & Packer, M. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab704 · Cited by 18
Hypoxia and Tissue Regeneration: Adaptive Mechanisms and Therapeutic Opportunities
Vélez, I. C. V., Domínguez, C. M. C., Sánchez, M. J. F., & Garavito-Aguilar, Z. V. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26199272 · Cited by 18
“This problem is reflected in 18 million deaths annually and approximately 64 million people living with Heart failure and functional limitations [77].”
Self-adaptive covalent coating for vascular stents: Coordinated coagulation-inflammation regulation to support re-endothelialization for atherosclerosis control.
Wang, Y., Zhu, Q.-J., Chen, Z., Wang, X.-Y., Ma, B.-X., Wang, Y., Xiao, Y., Luo, R., Zhang, W.-B., Wang, Y.-B., et al. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123600 · Cited by 18
AI-enhanced reconstruction of the 12-lead electrocardiogram via 3-leads with accurate clinical assessment
Mason, F., Pandey, A. C., Gadaleta, M., Topol, E. J., Muse, E. D., & Quer, G. (2024) · npj Digital Medicine · doi:10.1038/s41746-024-01193-7 · Cited by 30
“With over 300 million being performed worldwide on an annual basis 1 , the 12-lead electrocardiogram (ECG) has established itself as a bedrock diagnostic in the assessment of cardiovascular disease 2 – 5 .”
Canadian Cardiovascular Society/Canadian Cardiovascular Critical Care Society/Canadian Association of Interventional Cardiology Clinical Practice Update on Optimal Post Cardiac Arrest and Refractory Cardiac Arrest Patient Care.
van Diepen, S., May, M. L. L., Alfaro, P., Goldfarb, M. J., Luk, A., Mathew, R., Peretz-Larochelle, M., Rayner‐Hartley, E., Russo, J. J., Senaratne, J., et al. (2024) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2024.01.012 · Cited by 18
The Obesity Mortality Paradox in Patients with Pulmonary Embolism: Insights from a Tertiary Care Center
Alkhalfan, F., Bukhari, S., Rosenzveig, A., Moudgal, R., Khan, S., Ghoweba, M., Chaudhury, P., Cameron, S., & Tefera, L. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13082375 · Cited by 18
“Pulmonary embolism (PE) is the third most common cause of cardiovascular death in the United States [1] with an estimated mortality approaching 300,000 annually [2].”
BackgroundSelf-citation
Association between fasting stress hyperglycemia ratio and contrast-induced acute kidney injury in coronary angiography patients: a cross-sectional study
Shan, Y., Lin, M., Gu, F., Ying, S., Bao, X., Zhu, Q., Tao, Y., Chen, Z., Li, D., Zhang, W., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1300373 · Cited by 20
“Coronary artery disease (CAD) imposes a signi ﬁ cant global disease burden and stands as a prominent contributor to human mortality on a global scale (1, 2).”
Background
Interplay between microglia and environmental risk factors in Alzheimer's disease
Zhang, M., Liang, C., Chen, X., Cai, Y., & Cui, L. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.389745 · Cited by 30
Emery–Dreifuss muscular dystrophy Type 1 is associated with a high risk of malignant ventricular arrhythmias and end-stage heart failure
Cannie, D., Syrris, P., Protonotarios, A., Bakalakos, A., Pruny, J., Ditaranto, R., Martínez-Veira, C., Larrañaga-Moreira, J., Medo, K., Bermúdez-Jiménez, F., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad561 · Cited by 18
“32,33”
CaMKK2 alleviates myocardial ischemia/reperfusion injury by inhibiting oxidative stress and inflammation via the action on the AMPK-AKT-GSK-3β/Nrf2 signaling cascade
Li, C.-L., Hao, J., Qiu, H., & Xin, H. (2023) · Inflammation Research · doi:10.1007/s00011-023-01756-6 · Cited by 18
“Acute myocardial infarction is a fatal disease with a high death rate worldwide [1].”
Background
Prehospital transport and termination of resuscitation of cardiac arrest patients: A review of prehospital care protocols in the United States
Li, T., Koloden, D., Berkowitz, J., Luo, D., Luan, H., Gilley, C., Kurgansky, G., & Barbara, P. (2023) · Resuscitation Plus · doi:10.1016/j.resplu.2023.100397 · Cited by 18
Event-Triggered Adaptive Hybrid Torque-Position Control (ET-AHTPC) for Robot-Assisted Ankle Rehabilitation
Zuo, J., Liu, Q., Meng, W., Ai, Q., & Xie, S.-N. (2023) · IEEE transactions on industrial electronics (1982. Print) · doi:10.1109/tie.2022.3183358 · Cited by 18
The Role of Social Support in Cardiovascular Clinical Trial Participation among Black Men: Black Impact
Addison, S., Yang, Y., Metlock, F., King, M., McKoy, A., Williams, A., Gregory, J., Gray, D. M., Joseph, J. J., & Nolan, T. S. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191912041 · Cited by 17
Precision Medicine
Parker, A. M., Lees, J. G., Murray, A. J., Velagic, A., Lim, S. Y., Blasio, M. J. D., & Ritchie, R. H. (2025) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2025.101345 · Cited by 17
In vivo assessment of iPSC-cardiomyocyte loaded auxetic cardiac patches following chronic myocardial infarction.
Brazhkina, O., Park, J. H., Brown, M. E., Walcott, J. C., Han, J., Turchetti, A., Roychowdhury, S., Prasad, R. S., Kim, M. J., Itzhaki, I., et al. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123418 · Cited by 17
Effects of virtual reality with different modalities on upper limb recovery: a systematic review and network meta-analysis on optimizing stroke rehabilitation
Zhang, J., Liu, M.-X., Yue, J., Yang, J.-M., Xiao, Y., Yang, J., & Cai, E. (2025) · Frontiers in Neurology · doi:10.3389/fneur.2025.1544135 · Cited by 17
Predictors of gait speed post-stroke: A systematic review and meta-analysis.
Jasper, A., Lazaro, R. T., Mehta, S. P., Perry, L., Swanson, K., Reedy, K. R., & Schmidt, J. T. (2025) · Gait & Posture · doi:10.1016/j.gaitpost.2025.04.029 · Cited by 17
Huang-Lian-Jie-Du decoction inhibits CD4+ T cell infiltration into CNS in MCAO rats by regulating BBB
Chen, C., Li, C., Lan, X., Ren, Z., Zheng, Y., Chen, D., Xu, W., Cui, Y., Wang, X., Cheng, F., et al. (2025) · Phytomedicine · doi:10.1016/j.phymed.2025.156607 · Cited by 16
Trends and disparities in diabetes and atrial fibrillation related mortality in the United States: 1999-2020.
Sohail, M. U., Khan, T., Sajid, M., Imran, Z., Salim, H., Waqas, S. A., Mactaggart, S., & Ahmed, R. (2025) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2025.112112 · Cited by 17
Cardiorenal Syndrome in Heart Failure with Preserved Ejection Fraction: Insights into Pathophysiology and Recent Advances
Khandait, H. V., Sodhi, S. S., Khandekar, N., & Bhattad, V. B. (2025) · Cardiorenal Medicine · doi:10.1159/000542633 · Cited by 17
Application of Chalcone in the Structural Modification of Natural Products: An Overview
Quan, Y.-S., Liu, J.-Y., Wang, Y.-L., Liu, Z., Quan, Z.-S., Wang, S., & Yin, X.-M. (2024) · Chemistry and Biodiversity · doi:10.1002/cbdv.202401953 · Cited by 17
“Approximately 690 million cases of diabetes are expected by 2045 [106].”
Self-citation
Extracorporeal cardiopulmonary resuscitation for pediatric out-of-hospital cardiac arrest: A review of the Extracorporeal Life Support Organization Registry.
Olson, T. L., Kilcoyne, H., Morales-Demori, R., Rycus, P., Barbaro, R. P., Alexander, P. M. A., & Anders, M. M. (2024) · Resuscitation · doi:10.1016/j.resuscitation.2024.110380 · Cited by 17
Engineered nanovesicles mediated cardiomyocyte survival and neovascularization for the therapy of myocardial infarction.
Zhang, J., Zhang, B.-B., Zhang, L.-L., Xu, X., Cheng, Q.-W., Wang, Y.-Z., Li, Y.-Q., Jiang, R., Duan, S., & Zhang, L.-Z. (2024) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/j.colsurfb.2024.114135 · Cited by 17
A novel deep network with triangular-star spatial-spectral fusion encoding and entropy-aware double decoding for coronary artery segmentation
Dong, C., Dai, D.-W., Li, Z., & Xu, S.-Y. (2024) · Information Fusion · doi:10.1016/j.inffus.2024.102561 · Cited by 17
Evaluating the prognostic value of systemic immune‐inflammatory index in patients with acute decompensated heart failure
Qiu, J., Huang, X., Kuang, M.-B., Wang, C., Yu, C., He, S.-M., Xie, G., Wu, Z.-Y., Sheng, G.-T., & Zou, Y. (2024) · ESC Heart Failure · doi:10.1002/ehf2.14904 · Cited by 17
Development of composite functional tissue sheets using hiPSC-CMs and hADSCs to improve the cardiac function after myocardial infarction
Zhang, J., Li, J., Qu, X., Liu, Y., Sun, L., Harada, A., Hua, Y., Sougawa, N., Tabata, A., Liu, L., et al. (2024) · Bioactive Materials · doi:10.1016/j.bioactmat.2024.03.028 · Cited by 11
The Role of Spirituality in Stroke Survivors and Their Caregivers: A Systematic Review
Ambrosca, R., Bolgeo, T., Zeffiro, V., Alvaro, R., Vellone, E., & Pucciarelli, G. (2024) · Journal of religion and health · doi:10.1007/s10943-024-02029-0 · Cited by 17
“In the USA, approximately 3% of males and 2% of females were disabled because of stroke (Virani et al., 2021).”
Background
Machine Learning Identifies Higher Survival Profile In Extracorporeal Cardiopulmonary Resuscitation*
Crespo-Diaz, R., Wolfson, J., Yannopoulos, D., & Bartos, J. (2024) · Critical Care Medicine · doi:10.1097/ccm.0000000000006261 · Cited by 17

Authors: Virani, S. S., Alonso, A., Aparicio, H. J., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Cheng, S., Delling, F. N., Elkind, M. S. V., Evenson, K. R., Ferguson, J. F., Gupta, D. K., Khan, S. S., Kissela, B. M., Knutson, K. L., Lee, C. D., Lewis, T. T., Liu, J., Loop, M. S., Lutsey, P. L., Ma, J., Mackey, J., Martin, S. S., Matchar, D. B., Mussolino, M. E., Navaneethan, S. D., Perak, A. M., Roth, G. A., Samad, Z., Satou, G. M., Schroeder, E. B., Shah, S. H., Shay, C. M., Stokes, A., VanWagner, L. B., Wang, N.-Y., Tsao, C. W., & On behalf of the American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee
ORCID: Virani, Salim S.
Aparicio, Hugo J.
Benjamin, Emelia J.
Callaway, Clifton W.
Carson, April P.
Chamberlain, Alanna M.
Cheng, Susan
Delling, Francesca N.
Elkind, Mitchell S.V.
Evenson, Kelly R.
Ferguson, Jane F.
Gupta, Deepak K.
Khan, Sadiya S.
Knutson, Kristen L.
Lee, Chong D.
Lewis, Tené T.
Liu, Junxiu
Loop, Matthew Shane
Lutsey, Pamela L.
Ma, Jun
Mackey, Jason
Martin, Seth S.
Matchar, David B.
Navaneethan, Sankar D.
Perak, Amanda Marma
Roth, Gregory A.
Samad, Zainab
Satou, Gary M.
Schroeder, Emily B.
Shah, Svati H.
Shay, Christina M.
Stokes, Andrew
VanWagner, Lisa B.
Wang, Nae-Yuh
Tsao, Connie W.
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2021-02-23
Volume: 143
Issue: 8
Pages: e254-e743
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/cir.0000000000000950
PMC: PMC13036842
OpenAlex: W3122226502
Cited by: 5,784
References: 0
Citations by year: 2026: 503 · 2025: 658 · 2024: 915 · 2023: 1282 · 2022: 1694 · 2021: 646
FWCI: 764.95
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
PubMed Central (publishedVersion, cc-by-nc-nd)
eCommons - AKU (Aga Khan University) (submittedVersion)
Funders: National Heart, Lung, and Blood Institute (R03HL145195, R01HL155717)
National Institute of Neurological Disorders and Stroke (L30 NS093634, R01NS017950)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
Keywords: heart disease, stroke, cardiovascular disease statistics, cardiovascular risk factors, cardiovascular health behaviors, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary artery disease, heart failure, valvular heart disease, venous disease, peripheral arterial disease, quality of care, health care costs, social determinants of health, adverse pregnancy outcomes, cardiovascular disease prevention
MeSH terms: Global Burden of Disease, Diet, Healthy, American Heart Association, Blood Pressure, Cholesterol, Diabetes Mellitus, Heart Diseases, Hospitalization, Humans, Obesity, Risk Factors, Smoking, United States, Health Behavior, Exercise, Prevalence, Stroke

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Metadata

Record

About these checks