Cited by 791Physical Activity and HealthCardiovascular Health and Risk FactorsCardiovascular and exercise physiology

Sedentary Behavior and Cardiovascular Morbidity and Mortality: A Science Advisory From the American Heart Association

Young, Deborah Rohm, Hivert, Marie-France, Alhassan, Sofiya, Camhi, Sarah M., Ferguson, Jane F., Katzmarzyk, Peter T., Lewis, Cora E., Owen, Neville +3 more·2016·Circulation

Abstract

Epidemiological evidence is accumulating that indicates greater time spent in sedentary behavior is associated with all-cause and cardiovascular morbidity and mortality in adults such that some countries have disseminated broad guidelines that recommend minimizing sedentary behaviors. Research examining the possible deleterious consequences of excess sedentary behavior is rapidly evolving, with the epidemiology-based literature ahead of potential biological mechanisms that might explain the observed associations. This American Heart Association science advisory reviews the current evidence on sedentary behavior in terms of assessment methods, population prevalence, determinants, associations with cardiovascular disease incidence and mortality, potential underlying mechanisms, and interventions. Recommendations for future research on this emerging cardiovascular health topic are included. Further evidence is required to better inform public health interventions and future quantitative guidelines on sedentary behavior and cardiovascular health outcomes.

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Registry

Crossref · 10.1161/cir.0000000000000440

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152 of 152 references verified0 citation errors · 0 not checkable

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Authors
Young, D. R., Hivert, M.-F., Alhassan, S., Camhi, S. M., Ferguson, J. F., Katzmarzyk, P. T., Lewis, C. E., Owen, N., Perry, C. K., Siddique, J., & Yong, C. M.
Venue
Circulation
Published
2016-09-27
Volume
134
Issue
13
Pages
e262-79
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
OpenAlex
W2511876639
Cited by
791
References
152
Citations by year
2026: 44 · 2025: 69 · 2024: 75 · 2023: 109 · 2022: 72 · 2021: 115 · 2020: 112 · 2019: 70 · 2018: 65 · 2017: 52 · 2016: 6 · 2012: 1
FWCI
51.38
Type
journal article
Language
en
Open access
closed
Locations
  • Circulation (publishedVersion)
  • PubMed (publishedVersion)
  • Swinburne figshare (Swinburne University of Technology) (submittedVersion)
Topics
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords
sedentary behavior, cardiovascular disease, cardiovascular mortality, cardiovascular morbidity, all-cause mortality, prevalence, biological mechanisms, public health interventions
MeSH terms
American Heart Association, Cardiovascular Diseases, Humans, Morbidity, Motor Activity, Risk Factors, United States, Prevalence, Sedentary Behavior

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