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Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association
Open accessAbstract
Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). Methods: The American Heart Association, through its Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update. The 2021 Statistical Update is the product of a full year’s worth of effort by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. This year’s edition includes data on the monitoring and benefits of cardiovascular health in the population, an enhanced focus on social determinants of health, adverse pregnancy outcomes, vascular contributions to brain health, the global burden of cardiovascular disease, and further evidence-based approaches to changing behaviors related to cardiovascular disease. Results: Each of the 27 chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. Conclusions: The Statistical Update represents a critical resource for the lay public, policy makers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.
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“In North America, women bear a greater burden of disease due to a higher lifetime risk of stroke,1 a higher lifetime risk of death from stroke, and a higher risk of poor outcomes following stroke compared with men.2–4”
From Sex Differences in Physical Activity and Incident Stroke: A Systematic Review (2022) · cites this paper as [4]
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Schlapbach, L. J., GIBBONS, K. S., Butt, W. W., Kannankeril, P. J., Li, J. S., Hill, K. D., & for the Nitric Oxide During Cardiopulmonary Bypass to Improve Recovery in Infants With Congenital Heart Defects Follow-Up (NITRIC) Study Group and the Steroids to Reduce Systemic Inflammation after Infant Heart Surgery (STRESS) Network Investigators (2023) · Pediatric Critical Care Medicine · doi:10.1097/pcc.0000000000003344 · Cited by 5
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Natural Language Processing tool accurately identifies acute venous thromboembolism.
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Wang, W., Xu, D., Ding, J., Zhang, W., Fan, J., & Wang, D. (2023) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2023.3597 · Cited by 4
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Self-citationIn Vitro Anticoagulant Activity of Crude Protease of Bacillus tequilensis HSFI-5
Ethica, S., Raharjo, T. J., Zilda, D., & Hidayati, N. (2023) · INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY · doi:10.33086/ijmlst.v5i2.3791 · Cited by 4
“The risk of venous thromboembolism (VTE) increases in the first 3 months after the occurrence of an ischemic stroke (3,4).”
BackgroundMethodLee, H., Kang, B. G., Jo, J., Park, H., Yoon, S., Choi, S.-Y., & Kim, M. J. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1167468 · Cited by 4
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“Due to its rapid onset, limited treatment window, poor prognosis, and low survival rate, cardiac arrest continues to be a common occurrence throughout the world and has raised public health concerns globally (Xu et al. 2017; Virani et al. 2021).”
The Rise and Efficiency of Low Field Portable MRI Scanners
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“22 A pMRI that operates at very low magnetic fi eld strength (0.064 T) used at the bedside of critically ill patients in the ICU has a novel neuroimaging solution in the subacute phase, that can acquire T1-weighted (T1W), T2W, fl uid-attenuated inversion recovery (FLAIR), and diffusion-weighted…”
MethodInfluentialDiagnostic accuracy of telestroke consultation: a Louisiana based tele-network experience
Poongkunran, M., Ulep, R. D., Stuntz, G., Mitchell, S., Gaines, K. J., Vidal, G., Chehebar, D., Iwuchukwu, I., McGrade, H., Mohammed, A., et al. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1141059 · Cited by 4
Mewborn, E. K., Wright, D. B., & Wicks, M. (2023) · Journal of the American Association of Nurse Practitioners · doi:10.1097/jxx.0000000000000901 · Cited by 4
van Luik, E. V., Vaes, E., Vesseur, M., Wilmes, N., Meijs, D., Laven, S. A. J. S., Mohseni-Alsalhi, Z., de Haas, S., Spaanderman, M., & Ghossein-Doha, C. (2023) · Biomedicines · doi:10.3390/biomedicines11061622 · Cited by 4
“This may depend on menopause causing a drop in estrogen [88,89].”
BackgroundLi, H., Wang, T., Feng, Y.-Y., Sun, K., Huang, G., Cao, Y., & Xu, A.-L. (2023) · MedComm · doi:10.1002/mco2.289 · Cited by 4
“The present study aimed to thoroughly compare the therapeutic effects of optimally generated hiPSC-CMs for transplantation via different routes to the macaques with acute MI to address the following outcomes: (1) the cell retention, direct repair potential, and paracrine function in the MI heart after hiPSC-CMs transp…”
MethodKhan, S. K., Rawat, A., Khan, Z., Reyaz, I., Kumar, V., Batool, S., Yadav, R., & Hirani, S. (2023) · Cureus · doi:10.7759/cureus.41084 · Cited by 4
“However, even in low- and middle-income countries, the prevalence is expected to rise due to population aging and the growing burden of heart failure risk factors, such as high blood pressure [3-4].”
BackgroundSelf-citationLate-life depressive symptoms and white matter structural integrity within older Black adults
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Metadata
- Authors
- Virani, S. S., Alonso, A., Aparicio, H. J., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Cheng, S., Delling, F. N., Elkind, M. S. V., Evenson, K. R., Ferguson, J. F., Gupta, D. K., Khan, S. S., Kissela, B. M., Knutson, K. L., Lee, C. D., Lewis, T. T., Liu, J., Loop, M. S., Lutsey, P. L., Ma, J., Mackey, J., Martin, S. S., Matchar, D. B., Mussolino, M. E., Navaneethan, S. D., Perak, A. M., Roth, G. A., Samad, Z., Satou, G. M., Schroeder, E. B., Shah, S. H., Shay, C. M., Stokes, A., VanWagner, L. B., Wang, N.-Y., Tsao, C. W., & On behalf of the American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee
- ORCID
- Virani, Salim S.
- Aparicio, Hugo J.
- Benjamin, Emelia J.
- Callaway, Clifton W.
- Carson, April P.
- Chamberlain, Alanna M.
- Cheng, Susan
- Delling, Francesca N.
- Elkind, Mitchell S.V.
- Evenson, Kelly R.
- Ferguson, Jane F.
- Gupta, Deepak K.
- Khan, Sadiya S.
- Knutson, Kristen L.
- Lee, Chong D.
- Lewis, Tené T.
- Liu, Junxiu
- Loop, Matthew Shane
- Lutsey, Pamela L.
- Ma, Jun
- Mackey, Jason
- Martin, Seth S.
- Matchar, David B.
- Navaneethan, Sankar D.
- Perak, Amanda Marma
- Roth, Gregory A.
- Samad, Zainab
- Satou, Gary M.
- Schroeder, Emily B.
- Shah, Svati H.
- Shay, Christina M.
- Stokes, Andrew
- VanWagner, Lisa B.
- Wang, Nae-Yuh
- Tsao, Connie W.
- Venue
- Circulation
- Published
- 2021-02-23
- Volume
- 143
- Issue
- 8
- Pages
- e254-e743
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- PMC
- PMC13036842
- OpenAlex
- W3122226502
- Cited by
- 5,784
- References
- 0
- Citations by year
- 2026: 503 · 2025: 658 · 2024: 915 · 2023: 1282 · 2022: 1694 · 2021: 646
- FWCI
- 764.95
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- eCommons - AKU (Aga Khan University) (submittedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R03HL145195, R01HL155717)
- National Institute of Neurological Disorders and Stroke (L30 NS093634, R01NS017950)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Keywords
- heart disease, stroke, cardiovascular disease statistics, cardiovascular risk factors, cardiovascular health behaviors, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary artery disease, heart failure, valvular heart disease, venous disease, peripheral arterial disease, quality of care, health care costs, social determinants of health, adverse pregnancy outcomes, cardiovascular disease prevention
- MeSH terms
- Global Burden of Disease, Diet, Healthy, American Heart Association, Blood Pressure, Cholesterol, Diabetes Mellitus, Heart Diseases, Hospitalization, Humans, Obesity, Risk Factors, Smoking, United States, Health Behavior, Exercise, Prevalence, Stroke
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