Cited by 122Lipoproteins and Cardiovascular HealthDiabetes, Cardiovascular Risks, and LipoproteinsClinical practice guidelines implementation

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2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

Writing Committee Members, Blumenthal, Roger S., Morris, Pamela B., Gaudino, Mario, Johnson, Heather M., Anderson, Timothy S., Bittner, Vera A., Blankstein, Ron, Brewer, LaPrincess C., Cho, Leslie, de Ferranti, Sarah D., Gianos, Eugenia, Gluckman, Ty J., Gradney, Kristen F., Isiadinso, Ijeoma, Lloyd-Jones, Donald M., Marrs, Joel C., Martin, Seth S., McLain, Kellie H., Mehta, Laxmi S., Mora, Samia, Mulugeta, Wudeneh M., Natarajan, Pradeep, Navar, Ann Marie, Orringer, Carl E., Polonsky, Tamar S., Reynolds, Harmony R., Saseen, Joseph J., Shapiro, Michael D., Soffer, Daniel E., Tynes, Sheila A., Villavaso, Chloé D., Virani, Salim S., Wilkins, John T., Rohatgi, Anand, Kim, Samuel M., Alexander, Karen P., Anderson, Cheryl, Benziger, Catherine P., Dixon, Dave L., Duprez, Daniel, Ferdinand, Keith C., Goldberg, Anne Carol, Joshi, Parag, Knowles, Joshua W., Lavie Jr, Carl (Chip) J., Linderbaum, Jane A., McEvoy, John William, Mehta, Anurag, Merz, C. Noel Bairey, Nambi, Vijay, Orkaby, Ariela R., Peña,, Jessica M., Rosenson, Robert, Ruisinger, Janelle, Sandner, Sigrid E., Schott, Stacey L., Sperling, Laurence (Larry), Stone, Neil J., Toth, Peter, Ware, Adam L., Whelton, Seamus Paul, Young, James·2026·Circulation

DOI 10.1161/cir.0000000000001423

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Abstract

AIM: The “2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia” retires and replaces the “2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol.” METHODS: A comprehensive literature search was conducted from October 2024 to December 2024 to identify clinical studies, systematic reviews and meta-analyses, and other evidence conducted on human participants that were published in English from MEDLINE (through PubMed), EMBASE, the Cochrane Library, Agency for Healthcare Research and Quality, and other selected databases relevant to this guideline. STRUCTURE: The focus of this clinical practice guideline is to address the evaluation, management, and monitoring of individuals with dyslipidemias, including high blood cholesterol, hypertriglyceridemia, and elevated lipoprotein(a).

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Authors: Writing Committee Members, Blumenthal, R. S., Morris, P. B., Gaudino, M., Johnson, H. M., Anderson, T. S., Bittner, V. A., Blankstein, R., Brewer, L. C., Cho, L., de Ferranti, S. D., Gianos, E., Gluckman, T. J., Gradney, K. F., Isiadinso, I., Lloyd-Jones, D. M., Marrs, J. C., Martin, S. S., McLain, K. H., Mehta, L. S., Mora, S., Mulugeta, W. M., Natarajan, P., Navar, A. M., Orringer, C. E., Polonsky, T. S., Reynolds, H. R., Saseen, J. J., Shapiro, M. D., Soffer, D. E., Tynes, S. A., Villavaso, C. D., Virani, S. S., Wilkins, J. T., Rohatgi, A., Kim, S. M., Alexander, K. P., Anderson, C., Benziger, C. P., Dixon, D. L., Duprez, D., Ferdinand, K. C., Goldberg, A. C., Joshi, P., Knowles, J. W., Lavie Jr, C. (. J., Linderbaum, J. A., McEvoy, J. W., Mehta, A., Merz, C. N. B., Nambi, V., Orkaby, A. R., Peña, Rosenson, R., Ruisinger, J., Sandner, S. E., Schott, S. L., Sperling, L. (., Stone, N. J., Toth, P., Ware, A. L., Whelton, S. P., & Young, J.
Affiliations: American Hospital Association (US)
Former ACC/AHA Joint Committee on Clinical Practice Guidelines member; current member during the writing effort.
American Geriatrics Society (US)
American Association of Cardiovascular and Pulmonary Rehabilitation representative.
ACC/AHA Task Force on Performance Measures liaison.
Patient representative.
Association of Black Cardiologists (US)
American Pharmacists Association (US)
American College of Preventive Medicine (US)
National Lipid Association (US)
American Society for Preventive Cardiology representative.
AHA/ACC Guidelines Staff Consultant.
Preventive Cardiovascular Nurses Association representative.
American Diabetes Association (US)
ORCID: Blumenthal, Roger S.
Gaudino, Mario
Johnson, Heather M.
Anderson, Timothy S.
Bittner, Vera A.
Blankstein, Ron
Brewer, LaPrincess C.
Cho, Leslie
de Ferranti, Sarah D.
Gianos, Eugenia
Gluckman, Ty J.
Isiadinso, Ijeoma
Marrs, Joel C.
Mehta, Laxmi S.
Mora, Samia
Mulugeta, Wudeneh M.
Natarajan, Pradeep
Orringer, Carl E.
Polonsky, Tamar S.
Reynolds, Harmony R.
Saseen, Joseph J.
Soffer, Daniel E.
Wilkins, John T.
Rohatgi, Anand
Alexander, Karen P.
Benziger, Catherine P.
Dixon, Dave L.
Ferdinand, Keith C.
Goldberg, Anne Carol
Knowles, Joshua W.
Linderbaum, Jane A.
McEvoy, John William
Nambi, Vijay
Orkaby, Ariela R.
Peña,, Jessica M.
Rosenson, Robert
Ruisinger, Janelle
Sandner, Sigrid E.
Schott, Stacey L.
Stone, Neil J.
Toth, Peter
Ware, Adam L.
Whelton, Seamus Paul
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2026-04-28
Volume: 153
Issue: 17
Pages: e1154-e1276
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/cir.0000000000001423
OpenAlex: W7135196205
Cited by: 122
References: 752
Citations by year: 2026: 122
FWCI: 769.87
Type: journal article
Language: en
Update notices: correction (2026-06-22)
correction (2026-09-08)
Open access: closed
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
Keywords: dyslipidemia, dyslipidemia management, hypercholesterolemia, hypertriglyceridemia, serum cholesterol, lipid-lowering therapy, cardiovascular risk, lipid monitoring
MeSH terms: American Heart Association, Hypolipidemic Agents, Cardiology, Humans, United States, Dyslipidemias

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2026 ACC/AHA/AACVPR/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Dyslipidemia: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines

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