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Defining and Quantifying the Social Phenotype in Autism
Abstract
OBJECTIVE: Genetic and neurofunctional research in autism has highlighted the need for improved characterization of the core social disorder defining the broad spectrum of syndrome manifestations. METHOD: This article reviews the advantages and limitations of current methods for the refinement and quantification of this highly heterogeneous social phenotype. RESULTS: The study of social visual pursuit by use of eye-tracking technology is offered as a paradigm for novel tools incorporating these requirements and as a research effort that builds on the emerging synergy of different branches of social neuroscience. CONCLUSIONS: Advances in the area will require increased consideration of processes underlying experimental results and a closer approximation of experimental methods to the naturalistic demands inherent in real-life social situations.
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Cues of intention, when people mean something other than what they say, are typically conveyed via expressions conveyed by eyes and bodily gestures, or via suprasegmental aspects of speech.
“cues of intention – when people mean something other than what they say – are typically conveyed via expressions conveyed by eyes and bodily gestures, or via suprasegmental aspects of speech 15.”
From Parsing Heterogeneity in Autism Spectrum Disorders: Visual Scanning of Dynamic Social Scenes in School-Aged Children (2012) · cites this paper as [15]
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Metadata
- Authors
- Klin, A., Jones, W., Schultz, R., Volkmar, F., & Cohen, D.
- Affiliations
- Yale University (US)
- Venue
- American Journal of Psychiatry
- Published
- 2002-06-01
- Volume
- 159
- Issue
- 6
- Pages
- 895-908
- ISSN
- 0002-953X (ISSN-L)
- 1535-7228
- OpenAlex
- W2125189895
- Cited by
- 467
- References
- 51
- Citations by year
- 2026: 4 · 2025: 10 · 2024: 7 · 2023: 6 · 2022: 15 · 2021: 25 · 2020: 14 · 2019: 12 · 2018: 12 · 2017: 17 · 2016: 20 · 2015: 23 · 2014: 28 · 2013: 26 · 2012: 33
- FWCI
- 9.85
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD/DC-35482, HD03008, P01HD003008)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Social Sciences › Psychology › Developmental and Educational Psychology › Child and Animal Learning Development
- Keywords
- autism spectrum disorder, social phenotype, social dysfunction, eye tracking, social neuroscience
- MeSH terms
- Adult, Autistic Disorder, Cues, Eye Movements, Female, Fixation, Ocular, Forecasting, Humans, Interpersonal Relations, Male, Motion Pictures, Neurosciences, Nonverbal Communication, Phenotype, Research Design, Social Behavior Disorders, Social Perception, Visual Perception
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