Cited by 357Endometriosis Research and TreatmentMicroRNA in disease regulationExtracellular vesicles in disease

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MicroRNA-Regulated Pathways Associated with Endometriosis

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Ohlsson Teague, E. Maria C., Van der Hoek, Kylie H., Van der Hoek, Mark B., Perry, Naomi, Wagaarachchi, Prabhath, Robertson, Sarah A., Print, Cristin G., Hull, Louise M.·2009·Molecular Endocrinology

DOI 10.1210/me.2008-0387PMC PMC5419313

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Abstract

Endometriosis is a prevalent gynecological disease characterized by growth of endometriotic tissue outside the uterine cavity. MicroRNAs (miRNAs) are naturally occurring posttranscriptional regulatory molecules that potentially play a role in endometriotic lesion development. We assessed miRNA expression by microarray analysis in paired ectopic and eutopic endometrial tissues and identified 14 up-regulated (miR-145, miR-143, miR-99a, miR-99b, miR-126, miR-100, miR-125b, miR-150, miR-125a, miR-223, miR-194, miR-365, miR-29c and miR-1) and eight down-regulated (miR-200a, miR-141, miR-200b, miR-142-3p, miR-424, miR-34c, miR-20a and miR-196b) miRNAs. The differential expression of six miRNAs was confirmed by quantitative RT-PCR. An in silico analysis identified 3851 mRNA transcripts as putative targets of the 22 miRNAs. Of these predicted targets, 673 were also differentially expressed in ectopic vs. eutopic endometrial tissue, as determined by microarray. Functional analysis suggested that the 673 miRNA targets constitute molecular pathways previously associated with endometriosis, including c-Jun, CREB-binding protein, protein kinase B (Akt), and cyclin D1 (CCND1) signaling. These pathways appeared to be regulated both transcriptionally as well as by miRNAs at posttranscriptional level. These data are a rich and novel resource for endometriosis and miRNA research and suggest that the 22 miRNAs and their cognate mRNA target sequences constitute pathways that promote endometriosis. Accordingly, miRNAs are potential therapeutic targets for treating this disease.

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Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714
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Krek, A., Grün, D., Poy, M. N., Wolf, R., Rosenberg, L., Epstein, E. J., MacMenamin, P., da Piedade, I., Gunsalus, K. C., Stoffel, M., et al. (2005) · Nature Genetics · doi:10.1038/ng1536 · Cited by 4,603
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Iorio, M. V., Ferracin, M., Liu, C.-G., Veronese, A., Spizzo, R., Sabbioni, S., Magri, E., Pedriali, M., Fabbri, M., Campiglio, M., et al. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-1783 · Cited by 4,053
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Weighted Gene Co-expression Network Analysis of Endometriosis and Identification of Functional Modules Associated With Its Main Hallmarks
Bakhtiarizadeh, M. R., Hosseinpour, B., Shahhoseini, M., Korte, A., & Gifani, P. (2018) · Frontiers in Genetics · doi:10.3389/fgene.2018.00453 · Cited by 78
Downregulation of miR-183 inhibits apoptosis and enhances the invasive potential of endometrial stromal cells in endometriosis
Shi, X., Gu, L., Chen, J., Guo, X., & Shi, Y. (2013) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2013.1536 · Cited by 77
The role of micro-RNAs in the female reproductive tract
Nothnick, W. B. (2012) · Reproduction · doi:10.1530/rep-11-0240 · Cited by 77
Challenges in endometriosis miRNA studies — From tissue heterogeneity to disease specific miRNAs
Saare, M., Rekker, K., Laisk, T., Rahmioğlu, N., Zondervan, K. T., Salumets, A., Götte, M., & Peters, M. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.06.018 · Cited by 77
Genetics and Epigenetics of Infertility and Treatments on Outcomes
Pisarska, M. D., Chan, J. L., Lawrenson, K., Gonzalez, T. L., & Wang, E. T. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-01869 · Cited by 79
Post-Translational Modifications and Protein-Specific Isoforms in Endometriosis Revealed by 2D DIGE
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miR-194-3p represses the progesterone receptor and decidualization in eutopic endometrium from women with endometriosis
Pei, T., Liu, C., Liu, T., Xiao, L., Luo, B., Tan, J., Li, X., Zhou, G., Duan, C., & Huang, W. (2018) · Endocrinology · doi:10.1210/en.2018-00374 · Cited by 73
Enhanced miR-210 expression promotes the pathogenesis of endometriosis through activation of signal transducer and activator of transcription 3
Okamoto, M., Nasu, K., Abe, W., Aoyagi, Y., Kawano, Y., Kai, K., Moriyama, M., & Narahara, H. (2014) · Human Reproduction · doi:10.1093/humrep/deu332 · Cited by 75
miRNAs Regulation and Its Role as Biomarkers in Endometriosis
Marí‐Alexandre, J., Sánchez-Izquierdo, D., Gilabert–Estellés, J., Barceló‐Molina, M., Braza‐Boïls, A., & Sandoval, J. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17010093 · Cited by 71
H19X-encoded miR-424(322)/-503 cluster: emerging roles in cell differentiation, proliferation, plasticity and metabolism
Wang, F., Liang, R., Tandon, N., Matthews, E. R., Shrestha, S., Yang, J., Soibam, B., Yang, J., & Liu, Y. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2971-0 · Cited by 71
MicroRNAs expression profiling of eutopic proliferative endometrium in women with ovarian endometriosis
Laudanski, P., Charkiewicz, R., Kuzmicki, M., Szamatowicz, J., Charkiewicz, A., & Niklinski, J. (2013) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-11-78 · Cited by 70
Tissue and circulating microRNA influence reproductive function in endometrial disease
Louise Hull, M., & Nisenblat, V. (2013) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2013.07.012 · Cited by 69
Steroidal regulation of uterine miRNAs is associated with modulation of the miRNA biogenesis components Exportin-5 and Dicer1
Nothnick, W. B., Healy, C., & Hong, X. (2010) · Endocrine · doi:10.1007/s12020-009-9293-9 · Cited by 69
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Nothnick, W. B. (2017) · Seminars in Reproductive Medicine · doi:10.1055/s-0037-1599089 · Cited by 69
Serum miR-451a Levels Are Significantly Elevated in Women With Endometriosis and Recapitulated in Baboons (Papio anubis) With Experimentally-Induced Disease
Nothnick, W. B., Falcone, T., Joshi, N., Fazleabas, A. T., & Graham, A. R. (2016) · Reproductive Sciences · doi:10.1177/1933719116681519 · Cited by 68
Predictive Value of MicroRNAs in the Progression of Barrett Esophagus to Adenocarcinoma in a Long-Term Follow-up Study
Revilla‐Nuin, B., Parrilla, P., Lozano, J. J., de Haro, L. F. M., Ortiz, Á., Martínez, C. M., Munítiz, V., de Angulo, D. R., Bermejo, J., Molina, J., et al. (2012) · Annals of Surgery · doi:10.1097/sla.0b013e31826ddba6 · Cited by 67
MicroRNA-196b Regulates the Homeobox B7-Vascular Endothelial Growth Factor Axis in Cervical Cancer
How, C., Hui, A. B., Alajez, N. M., Shi, W., Boutros, P. C., Clarke, B. A., Yan, R., Pintilie, M., Fyles, A., Hedley, D. W., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0067846 · Cited by 67
Cellular, Histologic, and Molecular Changes Associated With Endometriosis and Ovarian Cancer
Neto, J. S., Kho, R. M., Siufi, D., Baracat, E. C., Anderson, K. S., & Abrão, M. S. (2013) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2013.07.021 · Cited by 67
Progestin regulated miRNAs that mediate progesterone receptor action in breast cancer
Cochrane, D. R., Jacobsen, B. M., Connaghan, K. D., Howe, E. N., Bain, D. L., & Richer, J. K. (2012) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.12.020 · Cited by 68
Microarray analysis of microRNA deregulation and angiogenesis-related proteins in endometriosis
Yang, R., Teng, H., Xu, X. H., Liu, S. Y., Wang, Y., Guo, F., & Liu, X. J. (2016) · Genetics and Molecular Research · doi:10.4238/gmr.15027826 · Cited by 64
Genome-wide profiling of long noncoding ribonucleic acid expression patterns in ovarian endometriosis by microarray
Sun, P.-R., Jia, S., Lin, H., Leng, J., & Lang, J. (2014) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.12.035 · Cited by 63
Plasma miRNAs Display Limited Potential as Diagnostic Tools for Endometriosis
Nisenblat, V., Sharkey, D. J., Wang, Z., Evans, S., Healey, M., Teague, E., Print, C. G., Robertson, S. A., & Hull, M. L. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-01464 · Cited by 63
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Qian, H., Maghsoudloo, M., Kaboli, P. J., Babaeizad, A., Cui, Y., Fu, J., Wang, Q., & İmani, S. (2024) · International Journal of Medical Sciences · doi:10.7150/ijms.102123 · Cited by 69
Genetic, epigenetic and stem cell alterations in endometriosis: new insights and potential therapeutic perspectives
Forte, A., Cipollaro, M., & Galderisi, U. (2013) · Clinical Science · doi:10.1042/cs20130099 · Cited by 63
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Ponsuksili, S., Tesfaye, D., Schellander, K., Hoelker, M., Hadlich, F., Schwerin, M., & Wimmers, K. (2014) · Biology of Reproduction · doi:10.1095/biolreprod.114.121392 · Cited by 64
microRNAs related to angiogenesis are dysregulated in endometrioid endometrial cancer
Ramón, L., Braza‐Boïls, A., Gilabert–Estellés, J., Chirivella, M., España, F., Estellés, A., & Gilabert–Estellés, J. (2012) · Human Reproduction · doi:10.1093/humrep/des292 · Cited by 61
The expression of microRNA-451 in human endometriotic lesions is inversely related to that of macrophage migration inhibitory factor (MIF) and regulates MIF expression and modulation of epithelial cell survival
Graham, A. R., Falcone, T., & Nothnick, W. B. (2015) · Human Reproduction · doi:10.1093/humrep/dev005 · Cited by 61
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Stejskalová, A., Fincke, V. E., Nowak, M. K., Schmidt, Y., Borrmann, K., von Wahlde, M., Schäfer, S. D., Kiesel, L., Greve, B., & Götte, M. (2021) · Scientific Reports · doi:10.1038/s41598-021-83645-8 · Cited by 58

Authors: Ohlsson Teague, E. M. C., Van der Hoek, K. H., Van der Hoek, M. B., Perry, N., Wagaarachchi, P., Robertson, S. A., Print, C. G., & Hull, L. M.
Affiliations: The University of Adelaide (AU)
Women's and Children's Hospital (AU)
University of Auckland (NZ)
ORCID: Robertson, Sarah A.
Print, Cristin G.
Venue: Molecular Endocrinology
Publisher: The Endocrine Society
Published: 2009-02
Volume: 23
Issue: 2
Pages: 265-275
ISSN: 0888-8809 (ISSN-L)
1944-9917
DOI: 10.1210/me.2008-0387
PMC: PMC5419313
OpenAlex: W1993162436
Cited by: 357
References: 65
Citations by year: 2026: 4 · 2025: 16 · 2024: 17 · 2023: 11 · 2022: 24 · 2021: 21 · 2020: 22 · 2019: 22 · 2018: 26 · 2017: 25 · 2016: 23 · 2015: 22 · 2014: 20 · 2013: 25 · 2012: 18
FWCI: 23.24
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Molecular Endocrinology (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
ResearchSpace (University of Auckland) (submittedVersion)
Topics: Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Extracellular vesicles in disease
Keywords: endometriosis, microRNA, miRNA expression profiling, ectopic endometrium, eutopic endometrium, miRNA target prediction, CREB-binding protein, Akt signaling, cyclin D1, post-transcriptional regulation, therapeutic target
MeSH terms: Endometriosis, Female, Gene Expression Regulation, Multigene Family, Humans, Molecular Sequence Data, Signal Transduction, Oligonucleotide Array Sequence Analysis, Gene Expression Profiling, MicroRNAs, JNK Mitogen-Activated Protein Kinases

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MicroRNA-Regulated Pathways Associated with Endometriosis

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