The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
D2Dopamine Receptors in Striatal Medium Spiny Neurons Reduce L-Type Ca2+Currents and Excitability via a Novel PLCβ1–IP3–Calcineurin-Signaling Cascade
Open accessAbstract
In spite of the recognition that striatal D 2 receptors are critical determinants in a variety of psychomotor disorders, the cellular mechanisms by which these receptors shape neuronal activity have remained a mystery. The studies presented here reveal that D 2 receptor stimulation in enkephalin-expressing medium spiny neurons suppresses transmembrane Ca 2+currents through L-type Ca 2+channels, resulting in diminished excitability. This modulation is mediated by G βγ activation of phospholipase C, mobilization of intracellular Ca 2+stores, and activation of the calcium-dependent phosphatase calcineurin. In addition to providing a unifying mechanism to explain the apparently divergent effects of D 2 receptors in striatal medium spiny neurons, this novel signaling linkage provides a foundation for understanding how this pivotal receptor shapes striatal excitability and gene expression.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“This Gαi coupled receptor has been shown to modulate the function of LTCC48,49.”
From Neuronal defects in a human cellular model of 22q11.2 deletion syndrome (2020) · cites this paper as [48]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The functional anatomy of basal ganglia disorders
Albin, R. L., Young, A. B., & Penney, J. B. (1989) · Trends in Neurosciences · doi:10.1016/0166-2236(89)90074-x · Cited by 5,353
Molecular and Cellular Basis of Addiction
Nestler, E. J., & Aghajanian, G. K. (1997) · Science · doi:10.1126/science.278.5335.58 · Cited by 1,295
Regulation of Gene Expression in Hippocampal Neurons by Distinct Calcium Signaling Pathways
Bading, H., Ginty, D. D., & Greenberg, M. E. (1993) · Science · doi:10.1126/science.8097060 · Cited by 1,157
The neostriatal mosaic: multiple levels of compartmental organization in the basal ganglia
Gerfen, C. R. (1992) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.15.030192.001441 · Cited by 1,004
Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens
Nicola, S. M., Surmeier, D. J., & Malenka, R. C. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.185 · Cited by 931
Self-citationThe Dopamine Hypothesis of Schizophrenia: A Review*
Meltzer, H. Y., & Stahl, S. M. (1976) · Schizophrenia Bulletin · doi:10.1093/schbul/2.1.19 · Cited by 883
Regulation of Phosphoinositide-specific Phospholipase C Isozymes
Rhee, S. G., & Bae, Y. S. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.24.15045 · Cited by 876
Calmodulin Is the Ca2+ Sensor for Ca2+-Dependent Inactivation of L-Type Calcium Channels
Peterson, B. Z., DeMaria, C. D., & Yue, D. T. (1999) · Neuron · doi:10.1016/s0896-6273(00)80709-6 · Cited by 856
The origins of two-state spontaneous membrane potential fluctuations of neostriatal spiny neurons
Wilson, C. J., & Kawaguchi, Y. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-07-02397.1996 · Cited by 798
Coordinated Expression of Dopamine Receptors in Neostriatal Medium Spiny Neurons
Surmeier, D. J., Song, W., & Yan, Z. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-20-06579.1996 · Cited by 762
Self-citation
Research works printed but not linked: 1
- Tukey JW (1977) Exploratory data analysis. (Addison-Wesley, Menlo Park, CA).
Cited by
Sorted by citations
The physiology, signaling, and pharmacology of dopamine receptors
Beaulieu, J.-M., & Gainetdinov, R. R. (2011) · Pharmacological Reviews · doi:10.1124/pr.110.002642 · Cited by 2,763
By Carrot or by Stick: Cognitive Reinforcement Learning in Parkinsonism
Frank, M. J., Seeberger, L. C., & O'Reilly, R. C. (2004) · Science · doi:10.1126/science.1102941 · Cited by 1,964
The molecular logic of endocannabinoid signalling
Piomelli, D. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1247 · Cited by 1,957
Modulation of Striatal Projection Systems by Dopamine
Gerfen, C. R., & Surmeier, D. J. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113641 · Cited by 1,700
Self-citationThe principal features and mechanisms of dopamine modulation in the prefrontal cortex
Seamans, J. K., & Yang, C. R. (2004) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2004.05.006 · Cited by 1,592
Reconsidering anhedonia in depression: Lessons from translational neuroscience
Treadway, M. T., & Zald, D. H. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.06.006 · Cited by 1,579
Surmeier, D. J., Ding, J., Day, M., Wang, Z., & Shen, W. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.03.008 · Cited by 1,203
Self-citationNeuronal Reward and Decision Signals: From Theories to Data
Schultz, W. (2015) · Physiological Reviews · doi:10.1152/physrev.00023.2014 · Cited by 1,126
Dopamine: Functions, Signaling, and Association with Neurological Diseases
Klein, M. O., Battagello, D. S., Cardoso, A. R., Hauser, D. N., Bittencourt, J. C., & Correa, R. G. (2019) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-018-0632-3 · Cited by 1,073
O’Reilly, R. C., & Frank, M. J. (2005) · Neural Computation · doi:10.1162/089976606775093909 · Cited by 1,124
Dopamine reward prediction-error signalling: A two-component response
Schultz, W. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2015.26 · Cited by 1,036
Striatal Plasticity and Basal Ganglia Circuit Function
Kreitzer, A. C., & Malenka, R. C. (2008) · Neuron · doi:10.1016/j.neuron.2008.11.005 · Cited by 1,071
Dopamine-mediated regulation of corticostriatal synaptic plasticity
Calabresi, P., Picconi, B., Tozzi, A., & Di Filippo, M. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.03.001 · Cited by 865
Neve, K. A., Seamans, J. K., & Trantham‐Davidson, H. (2004) · Journal of Receptors and Signal Transduction · doi:10.1081/rrs-200029981 · Cited by 836
Frank, M. J. (2005) · Journal of Cognitive Neuroscience · doi:10.1162/0898929052880093 · Cited by 925
Day, M., Wang, Z., Ding, J., An, X., Ingham, C. A., Shering, A. F., Wokosin, D., Ilijic, E., Sun, Z., Sampson, A. R., et al. (2006) · Nature Neuroscience · doi:10.1038/nn1632 · Cited by 745
Self-citationDopaminergic modulation of synaptic transmission in cortex and striatum
Tritsch, N. X., & Sabatini, B. L. (2012) · Neuron · doi:10.1016/j.neuron.2012.09.023 · Cited by 756
The Inositol Trisphosphate/Calcium Signaling Pathway in Health and Disease
Berridge, M. J. (2016) · Physiological Reviews · doi:10.1152/physrev.00006.2016 · Cited by 779
Hold your horses: a dynamic computational role for the subthalamic nucleus in decision making
Frank, M. J. (2006) · Neural Networks · doi:10.1016/j.neunet.2006.03.006 · Cited by 706
Monitoring Rapid Chemical Communication in the Brain
Robinson, D. L., Hermans, A., Seipel, A. T., & Wightman, R. M. (2008) · Chemical Reviews · doi:10.1021/cr068081q · Cited by 672
Functional organization of the basal ganglia: Therapeutic implications for Parkinson's disease
Obeso, J. A., Rodríguez-Oroz, M. C., Benítez‐Temiño, B., Blesa, F. J., Guridi, J., Marı́n, C., & Rodrı́guez, M. (2008) · Movement Disorders · doi:10.1002/mds.22062 · Cited by 739
Lüscher, C., & Huber, K. M. (2010) · Neuron · doi:10.1016/j.neuron.2010.01.016 · Cited by 627
Karbach, J., & Verhaeghen, P. (2014) · Psychological Science · doi:10.1177/0956797614548725 · Cited by 589
Frank, M. J., & Claus, E. D. (2006) · Psychological Review · doi:10.1037/0033-295x.113.2.300 · Cited by 596
Physiology and pharmacology of striatal neurons
Kreitzer, A. C. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135422 · Cited by 530
Dopamine receptors – IUPHAR R eview 13
Beaulieu, J., Espinoza, S., & Gainetdinov, R. R. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12906 · Cited by 561
Wang, Z., Li, K., Day, M., Ronesi, J. A., Yin, H. H., Ding, J., Tkatch, T., Lovinger, D. M., & Surmeier, D. J. (2006) · Neuron · doi:10.1016/j.neuron.2006.04.010 · Cited by 513
Self-citationFrank, M. J., & O'Reilly, R. C. (2006) · Behavioral Neuroscience · doi:10.1037/0735-7044.120.3.497 · Cited by 472
Opponency revisited: competition and cooperation between dopamine and serotonin
Boureau, Y.-L., & Dayan, P. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.151 · Cited by 456
An Update on the Mechanisms of the Psychostimulant Effects of Caffeine
Ferré, S. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05196.x · Cited by 440
Cholinergic interneuron characteristics and nicotinic properties in the striatum
Zhou, F., Wilson, C. J., & Dani, J. A. (2002) · Journal of Neurobiology · doi:10.1002/neu.10150 · Cited by 465
Mallet, N. P., Ballion, B., Moine, C. L., & Gonon, F. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4439-05.2006 · Cited by 413
Tseng, K. Y., & O'Donnell, P. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.1021-04.2004 · Cited by 402
Banishing the homunculus: Making working memory work
Hazy, T. E., Frank, M. J., & O’Reilly, R. C. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.04.067 · Cited by 385
Waltz, J. A., Frank, M. J., Robinson, B. M., & Gold, J. M. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.09.042 · Cited by 326
The CRAC Channel Activator STIM1 Binds and Inhibits L-Type Voltage-Gated Calcium Channels
Park, C. Y., Shcheglovitov, A., & Dolmetsch, R. E. (2010) · Science · doi:10.1126/science.1191027 · Cited by 321
Dopamine, Immunity, and Disease
Channer, B., Matt, S. M., Nickoloff-Bybel, E. A., Pappa, V., Agarwal, Y., Wickman, J. R., & Gaskill, P. J. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.122.000618 · Cited by 328
Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease
Xu, Y., Yan, J., Zhou, P., Li, J., Gao, H., Xia, Y., & Wang, Q. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.02.002 · Cited by 304
Olson, P. A., Tkatch, T., Hernández‐López, S., Ulrich, S., Ilijić, E., Mugnaini, E., Zhang, H., Борисович, Б. И., & Surmeier, D. J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3327-04.2005 · Cited by 270
Self-citationCompetitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors
Higley, M. J., & Sabatini, B. L. (2010) · Nature Neuroscience · doi:10.1038/nn.2592 · Cited by 271
Rubı́, B., Ljubicic, S., Pournourmohammadi, S., Carobbio, S., Armanet, M., Bartley, C., & Maechler, P. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m505560200 · Cited by 257
West, A. R., & Grace, A. A. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-01-00294.2002 · Cited by 252
Centonze, D., Grande, C., Usiello, A., Gubellini, P., Erbs, E., Martín, A. B., Pisani, A., Tognazzi, N., Bernardi, G., Moratalla, R., et al. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-15-06245.2003 · Cited by 244
Differential Excitability and Modulation of Striatal Medium Spiny Neuron Dendrites
Day, M., Wokosin, D. L., Plotkin, J. L., Tian, X., & Surmeier, D. J. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1840-08.2008 · Cited by 242
Self-citationDopamine Receptors and Neurodegeneration
Rangel‐Barajas, C., Israel, C. W., & Florán, B. (2015) · Aging and Disease · doi:10.14336/ad.2015.0330 · Cited by 242
Dopamine Modulates Release from Corticostriatal Terminals
Bamford, N. S., Robinson, S., Palmiter, R. D., Joyce, J. A., Moore, C., & Meshul, C. K. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2891-04.2004 · Cited by 248
Neurocomputational models of basal ganglia function in learning, memory and choice
Cohen, M. X., & Frank, M. J. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.09.029 · Cited by 248
Kotecha, S. A., Oak, J. N., Jackson, M. F., Perez, Y., Orser, B. A., Tol, H. H. M. V., & MacDonald, J. F. (2002) · Neuron · doi:10.1016/s0896-6273(02)00859-0 · Cited by 229
Maurice, N., Mercer, J. N., Chan, C. S., Hernández‐López, S., Held, J. E., Tkatch, T., & Surmeier, D. J. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.2155-04.2004 · Cited by 222
Self-citationMaladaptive striatal plasticity in l-DOPA-induced dyskinesia
Cenci, M. A., & Konradi, C. L. (2010) · Progress in brain research · doi:10.1016/s0079-6123(10)83011-0 · Cited by 229
Calcineurin in memory and bidirectional plasticity
Mansuy, I. M. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.10.046 · Cited by 200
Receptor–receptor interactions within receptor mosaics. Impact on neuropsychopharmacology
Fuxé, K., Marcellino, D. J., Rivera, A., Dı́az-Cabiale, Z., Filip, M., Gago, B., Roberts, D. C. S., Langel, Ü., Genedani, S., Ferraro, L., et al. (2008) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.11.007 · Cited by 200
Jung, K., Mangieri, R. A., Stapleton, C. J., Kim, J., Fegley, D., Wallace, M., Mackie, K., & Piomelli, D. (2005) · Molecular Pharmacology · doi:10.1124/mol.105.013961 · Cited by 197
Xing, B., Li, Y.-C., & Gao, W.-J. (2016) · Brain Research · doi:10.1016/j.brainres.2016.01.005 · Cited by 196
Reappraising striatal D1- and D2-neurons in reward and aversion
Soares‐Cunha, C., Coimbra, B., Sousa, N., & Rodrigues, A. J. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.05.021 · Cited by 203
Dobbs, L. K., Kaplan, A. R., Lemos, J. C., Matsui, A., Rubinstein, M., & Alvarez, V. A. (2016) · Neuron · doi:10.1016/j.neuron.2016.04.031 · Cited by 192
Neuronal defects in a human cellular model of 22q11.2 deletion syndrome
Khan, T. A., Revah, O., Gordon, A., Yoon, S.-J., Krawisz, A. K., Goold, C., Sun, Y., Kim, C. H., Tian, Y., Li, M.-Y., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-1043-9 · Cited by 186
Azdad, K., Gall, D., Woods, A. S., Ledent, C. A., Ferré, S., & Schiffmann, S. N. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.144 · Cited by 185
Coordinated expression of muscarinic receptor messenger RNAs in striatal medium spiny neurons
Yan, Z., Flores‐Hernández, J., & Surmeier, D. J. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00039-2 · Cited by 179
Self-citationCalcium signaling dysfunction in schizophrenia: a unifying approach
Lidow, M. S. (2003) · Brain Research Reviews · doi:10.1016/s0165-0173(03)00203-0 · Cited by 174
Adenosine–Dopamine Interactions in the Pathophysiology and Treatment of CNS Disorders
Fuxé, K., Marcellino, D. J., Borroto‐Escuela, D. O., Guescini, M., Fernández‐Dueñas, V., Tanganelli, S., Rivera, A., Ciruela, F., & Agnati, L. F. (2010) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2009.00126.x · Cited by 175
Goldberg, J. A., & Wilson, C. J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2734-05.2005 · Cited by 172
Calcineurin regulation of neuronal plasticity
Groth, R. D., Dunbar, R. L., & Mermelstein, P. G. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.09.002 · Cited by 167
Frank, M. J., Scheres, A., & Sherman, S. J. (2007) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2007.2058 · Cited by 168
Calabresi, P., Gubellini, P., Picconi, B., Centonze, D., Pisani, A., Bonsi, P., Greengard, P., Hipskind, R. A., Borrelli, E., & Bernardi, G. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-14-05110.2001 · Cited by 163
Kawagoe, R., Takikawa, Y., & Hikosaka, O. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00721.2003 · Cited by 158
Atallah, H. E., Frank, M. J., & O’Reilly, R. C. (2004) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2004.06.004 · Cited by 171
Dopaminergic Modulation of Axon Collaterals Interconnecting Spiny Neurons of the Rat Striatum
Guzmán, J. N., Hernández, A., Galarraga, E., Tapia, D., Laville, A., Vergara, R. O., Aceves, J., & Bargas, J. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-26-08931.2003 · Cited by 161
Self-citationAdenosine A2A receptors, dopamine D2 receptors and their interactions in Parkinson's disease
Fuxé, K., Marcellino, D. J., Genedani, S., & Agnati, L. F. (2007) · Movement Disorders · doi:10.1002/mds.21440 · Cited by 159
Namkung, Y., & Sibley, D. R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m408319200 · Cited by 156
Aberrant Striatal Activity in Parkinsonism and Levodopa-Induced Dyskinesia
Ryan, M., Bair-Marshall, C. J., & Nelson, A. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.05.059 · Cited by 166
Li, J., Guo, Y., Schroeder, F. A., Youngs, R. M., Schmidt, T. W., Ferris, C. F., Konradi, C. L., & Akbarian, S. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02569.x · Cited by 155
A dopaminergic basis for working memory, learning and attentional shifting in Parkinsonism
Moustafa, A. A., Sherman, S. J., & Frank, M. J. (2008) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2008.07.011 · Cited by 192
Striatal D1 and D2 signaling differentially predict learning from positive and negative outcomes
Cox, S. M. L., Frank, M. J., Larcher, K. M.-H., Fellows, L. K., Clark, C. A., Leyton, M., & Dagher, A. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2014.12.070 · Cited by 144
Planert, H., Berger, T. K., & Silberberg, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057054 · Cited by 137
Hopf, F. W., Cascini, M. G., Gordon, A. S., Diamond, I., & Bonci, A. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-12-05079.2003 · Cited by 146
Dopaminergic modulation of striatal neurons, circuits, and assemblies
Surmeier, D. J., Carrillo‐Reid, L., & Bargas, J. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.08.051 · Cited by 141
Self-citationChiu, C. Q., Puente, N., Grandes, P., & Castillo, P. E. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0736-10.2010 · Cited by 143
Deng, Y., Lei, W., & Reiner, A. J. (2006) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2006.07.001 · Cited by 148
Muscarinic and Nicotinic Cholinergic Mechanisms in the Mesostriatal Dopamine Systems
Zhou, F.-M., Wilson, C. J., & Dani, J. A. (2003) · The Neuroscientist · doi:10.1177/1073858402239588 · Cited by 146
Tseng, K. Y., & O'Donnell, P. (2007) · Synapse · doi:10.1002/syn.20432 · Cited by 141
Adenosine A2A-dopamine D2 receptor–receptor heteromers. Targets for neuro-psychiatric disorders
Ferré, S., Ciruela, F., Canals, M., Marcellino, D. J., Burgueño, J., Casadó, V., Hillion, J., Torvinen, M., Fanelli, F., de Benedetti, P., et al. (2004) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2004.02.014 · Cited by 139
Dopamine Receptors and Parkinson's Disease
Hisahara, S., & Shimohama, S. (2011) · International Journal of Medicinal Chemistry · doi:10.1155/2011/403039 · Cited by 139
GABAergic inhibition in the neostriatum
Wilson, C. J. (2007) · Progress in brain research · doi:10.1016/s0079-6123(06)60006-x · Cited by 143
Immunomodulatory Effects Mediated by Dopamine
Arreola, R., Álvarez-Herrera, S., Pérez‐Sánchez, G., Becerril‐Villanueva, E., Cruz-Fuentes, C. S., Flores-Gutiérrez, E. O., Garcés-Alvarez, M. E., de la Cruz-Aguilera, D. L., Medina‐Rivero, E., Hurtado‐Alvarado, G., et al. (2016) · Journal of Immunology Research · doi:10.1155/2016/3160486 · Cited by 141
Enhanced GABA Transmission Drives Bradykinesia Following Loss of Dopamine D2 Receptor Signaling
Lemos, J. C., Friend, D. M., Kaplan, A. R., Shin, J. H., Rubinstein, M., Kravitz, A. V., & Alvarez, V. A. (2016) · Neuron · doi:10.1016/j.neuron.2016.04.040 · Cited by 130
Swart, J. C., Froböse, M. I., Cook, J. L., Geurts, D. E. M., Frank, M. J., Cools, R., & den Ouden, H. E. M. (2017) · eLife · doi:10.7554/elife.22169 · Cited by 140
Spontaneous Voltage Oscillations in Striatal Projection Neurons in a Rat Corticostriatal Slice
Vergara, R. O., Rick, C., Hernández‐López, S., Laville, J. A., Guzmán, J. N., Galarraga, E., Surmeier, D. J., & Bargas, J. (2003) · The Journal of Physiology · doi:10.1113/jphysiol.2003.050799 · Cited by 125
Self-citationPlastic Corticostriatal Circuits for Action Learning
Costa, R. M. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1390.015 · Cited by 126
Input- and Cell-Type-Specific Endocannabinoid-Dependent LTD in the Striatum
Wu, Y., Kim, J., Tawfik, V. L., Lalchandani, R. R., Scherrer, G., & Ding, J. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.12.005 · Cited by 117
Transient Calcium and Dopamine Increase PKA Activity and DARPP-32 Phosphorylation
Lindskog, M., Kim, M., Wikström, M. A., Blackwell, K. T., & Kotaleski, J. H. (2006) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0020119 · Cited by 121
Bender, K. J., Ford, C., & Trussell, L. O. (2010) · Neuron · doi:10.1016/j.neuron.2010.09.026 · Cited by 128
Cav1.3 channels control D2-autoreceptor responses via NCS-1 in substantia nigra dopamine neurons
Dragicevic, E., Pötschke, C., Duda, J., Schlaudraff, F., Lammel, S., Schiemann, J. M., Fauler, M., Hetzel, A., Watanabe, M., Luján, R., et al. (2014) · Brain · doi:10.1093/brain/awu131 · Cited by 128
Stevens, T. R., Krueger, S. R., Fitzsimonds, R. M., & Picciotto, M. R. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-31-10093.2003 · Cited by 119
Calcium signaling in Parkinson’s disease
Calí, T., Ottolini, D., & Brini, M. (2014) · Cell and Tissue Research · doi:10.1007/s00441-014-1866-0 · Cited by 124
Carr, D. B., Andrews, G. D., Glen, W. B., & Lavı́n, A. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.141671 · Cited by 119
Perez‐Rosello, T., Figueroa, A., Salgado, H., Vilchis, C., Tecuapetla, F., Guzmán, J. N., Galarraga, E., & Bargas, J. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00853.2004 · Cited by 115
Self-citationFerré, S., Agnati, L. F., Ciruela, F., Lluı́s, C., Woods, A. S., Fuxé, K., & Franco, R. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2007.01.007 · Cited by 116
Neurocomputational models of motor and cognitive deficits in Parkinson’s disease
Wiecki, T. V., & Frank, M. J. (2010) · Progress in brain research · doi:10.1016/s0079-6123(10)83014-6 · Cited by 111
Inversion of Dopamine Responses in Striatal Medium Spiny Neurons and Involuntary Movements
Li, L., DeLong, M. R., & Papa, S. M. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1176-08.2008 · Cited by 115
Metadata
- Authors
- Hernández-López, S., Tkatch, T., Perez-Garci, E., Galarraga, E., Bargas, J., Hamm, H., & Surmeier, D. J.
- Affiliations
- Universidad Nacional Autónoma de México (MX)
- Northwestern University (US)
- Venue
- The Journal of Neuroscience
- Publisher
- Society for Neuroscience
- Published
- 2000-12-15
- Volume
- 20
- Issue
- 24
- Pages
- 8987-8995
- ISSN
- 0270-6474 (ISSN-L)
- 1529-2401
- OpenAlex
- W4295332810
- Cited by
- 443
- References
- 60
- Citations by year
- 2026: 9 · 2025: 7 · 2024: 8 · 2023: 15 · 2022: 14 · 2021: 8 · 2020: 15 · 2019: 14 · 2018: 19 · 2017: 13 · 2016: 23 · 2015: 22 · 2014: 20 · 2013: 15 · 2012: 18
- FWCI
- 5.67
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Neuroscience (publishedVersion, cc-by-nc-sa)
- Funders
- National Institutes of Health (NS 34696)
- National Institute on Drug Abuse (DA-12958, R01DA012958)
- National Eye Institute (R01- EY010291)
- Fogarty International Center (TW 01214)
- National Institute of Neurological Disorders and Stroke (NS 34696, R01NS034696, R37NS034696)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Receptor Mechanisms and Signaling
- Keywords
- dopamine D2 receptor, striatal medium spiny neurons, L-type calcium current, neuronal excitability, PLCB1, IP3 signaling, calcineurin, Gβγ signaling, intracellular calcium stores
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review