Cited by 172Neuroscience and Neuropharmacology ResearchNeural dynamics and brain functionConnexins and lens biology

The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Synaptic Interactions of Late-Spiking Neocortical Neurons in Layer 1

Open access

Chu, Zhiguo, Galarreta, Mario, Hestrin, Shaul·2003·The Journal of Neuroscience

DOI 10.1523/jneurosci.23-01-00096.2003PMC PMC6742162

Open this paper in CoChat — free account Open PDF

Abstract

Layer 1 of the neocortex is an important zone in which synaptic integration of inputs originating from a variety of cerebral regions is thought to take place. Layer 1 does not contain pyramidal cells, and several histochemical studies have suggested that most layer 1 neurons are GABAergic. However, although layer 1 neurons could be an important source of inhibition in this layer, the synaptic action of these neurons and the identity of their postsynaptic targets are unknown. We studied the physiological properties and synaptic interactions of a class of cells within layer 1 called late-spiking (LS) cells. The dendrites and axons of layer 1 LS cells were confined primarily to layer 1. Using paired recording, we showed that LS cells formed GABAergic connections with other LS cells as well as with non-LS cells in layer 1 and with pyramidal cells in layer 2/3. We also found that layer 2/3 pyramidal neurons provide excitatory inputs to LS cells. It has been suggested previously that GABAergic neurons belonging to the same class in the cortex are electrically coupled. In agreement with that hypothesis, we found that LS cells were interconnected by electrical coupling (83%), whereas electrical coupling between LS cells and non-LS cells was infrequent (2%). Thus, we provide evidence showing that a group of GABAergic neurons within layer 1 are specifically interconnected by electrical coupling and can provide significant inhibitory inputs to neurons in layer 1 and to distal dendrites of pyramidal cells.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1523/jneurosci.23-01-00096.2003

Cites

38 of 38 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Distributed hierarchical processing in the primate cerebral cortex
Felleman, D. J., & Van Essen, D. C. (1991) · Cerebral Cortex · doi:10.1093/cercor/1.1.1 · Cited by 7,783
Preface: Cerebral Cortex Has Come of Age
Goldman, P. S., & RAKIC, P. T. (1991) · Cerebral Cortex · doi:10.1093/cercor/1.1.1-a · Cited by 3,537
GABAergic cell subtypes and their synaptic connections in rat frontal cortex
Kawaguchi, Y. (1997) · Cerebral Cortex · doi:10.1093/cercor/7.6.476 · Cited by 1,416
Two networks of electrically coupled inhibitory neurons in neocortex
Gibson, J. R., Beierlein, M., & Connors, B. W. (1999) · Nature · doi:10.1038/47035 · Cited by 1,404
A network of fast-spiking cells in the neocortex connected by electrical synapses
Galarreta, M., & Hestrin, S. (1999) · Nature · doi:10.1038/47029 · Cited by 960
Self-citation
Proximally targeted GABAergic synapses and gap junctions synchronize cortical interneurons
Tamás, G., Buhl, E. H., Lörincz, A., & Somogyi, P. (2000) · Nature Neuroscience · doi:10.1038/73936 · Cited by 648
Synchronous Activity of Inhibitory Networks in Neocortex Requires Electrical Synapses Containing Connexin36
Deans, M. R., Gibson, J. R., Sellitto, C., Connors, B. W., & Paul, D. L. (2001) · Neuron · doi:10.1016/s0896-6273(01)00373-7 · Cited by 579
Physiological subgroups of nonpyramidal cells with specific morphological characteristics in layer II/III of rat frontal cortex
Kawaguchi, Y. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-04-02638.1995 · Cited by 533
Impaired Electrical Signaling Disrupts Gamma Frequency Oscillations in Connexin 36-Deficient Mice
Hormuzdi, S. G., Pais, I., LeBeau, F. E. N., Towers, S. K., Rozov, A., Buhl, E. H., Whittington, M. A., & Monyer, H. (2001) · Neuron · doi:10.1016/s0896-6273(01)00387-7 · Cited by 522
Electrical synapses between Gaba-Releasing interneurons
Galarreta, M., & Hestrin, S. (2001) · Nature Reviews Neuroscience · doi:10.1038/35077566 · Cited by 434
Self-citation

Show all 38 references

Sorted by citations

Canonical Microcircuits for Predictive Coding
Bastos, A. M., Usrey, W. M., Adams, R. A., Mangun, G. R., Fries, P., & Friston, K. J. (2012) · Neuron · doi:10.1016/j.neuron.2012.10.038 · Cited by 2,421
“These L1 cells are almost all inhibitory and interconnect strongly with each other, via electrical connections and chemical synapses (Chu et al., 2003).”
Influential
GABAergic Interneurons in the Neocortex: From Cellular Properties to Circuits
Tremblay, R., Lee, S., & Rudy, B. (2016) · Neuron · doi:10.1016/j.neuron.2016.06.033 · Cited by 2,033
Adult mouse cortical cell taxonomy revealed by single cell transcriptomics
Tasic, B., Menon, V., Nguyen, T. N., Kim, T. K., Jarsky, T., Yao, Z., Levi, B., Gray, L. T., Sorensen, S. A., Dolbeare, T., et al. (2016) · Nature Neuroscience · doi:10.1038/nn.4216 · Cited by 1,714
Large-scale model of mammalian thalamocortical systems
Izhikevich, E. M., & Edelman, G. M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712231105 · Cited by 1,021
Hippocampal GABAergic Inhibitory Interneurons
Pelkey, K. A., Chittajallu, R., Craig, M. T., Tricoire, L., Wester, J. C., & McBain, C. J. (2017) · Physiological Reviews · doi:10.1152/physrev.00007.2017 · Cited by 889
A disinhibitory microcircuit for associative fear learning in the auditory cortex
Letzkus, J. J., Wolff, S. B. E., Meyer, E. M. M., Tovote, P., Courtin, J., Herry, C., & Lüthi, A. (2011) · Nature · doi:10.1038/nature10674 · Cited by 840
ELECTRICAL SYNAPSES IN THE MAMMALIAN BRAIN
Connors, B. W., & Long, M. A. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131128 · Cited by 784
The largest group of superficial neocortical GABAergic interneurons expresses ionotropic serotonin receptors
Lee, S., Hjerling-Leffler, J., Zagha, E., Fishell, G., & Rudy, B. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.1869-10.2010 · Cited by 600
Two dynamically distinct inhibitory networks in layer 4 of the neocortex
Beierlein, M., Gibson, J. R., & Connors, B. W. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00283.2003 · Cited by 591
Genetic Fate Mapping Reveals That the Caudal Ganglionic Eminence Produces a Large and Diverse Population of Superficial Cortical Interneurons
Miyoshi, G., Hjerling-Leffler, J., Karayannis, T., Sousa, V. H., Butt, S. J. B., Battiste, J., Johnson, J. E., Machold, R. P., & Fishell, G. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.4515-09.2010 · Cited by 559
Selective Activation of the Deep Layers of the Human Primary Visual Cortex by Top-Down Feedback
Kok, P., Bains, L. J., van Mourik, T., Norris, D. G., & de Lange, F. P. (2016) · Current Biology · doi:10.1016/j.cub.2015.12.038 · Cited by 397
Supralinear increase of recurrent inhibition during sparse activity in the somatosensory cortex
Kapfer, C., Glickfeld, L. L., Atallah, B. V., & Scanziani, M. (2007) · Nature Neuroscience · doi:10.1038/nn1909 · Cited by 427
Disinhibition, a Circuit Mechanism for Associative Learning and Memory
Letzkus, J. J., Wolff, S. B. E., & Lüthi, A. (2015) · Neuron · doi:10.1016/j.neuron.2015.09.024 · Cited by 430
Neural elements for predictive coding
Shipp, S. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.01792 · Cited by 340
The organization of two new cortical interneuronal circuits
Jiang, X., Wang, G., Lee, A. J., Stornetta, R. L., & Zhu, J. J. (2013) · Nature Neuroscience · doi:10.1038/nn.3305 · Cited by 338
Repetition suppression and its contextual determinants in predictive coding
Auksztulewicz, R., & Friston, K. (2016) · Cortex · doi:10.1016/j.cortex.2015.11.024 · Cited by 307
Cross-Modality Sharpening of Visual Cortical Processing through Layer-1-Mediated Inhibition and Disinhibition
Ibrahim, L. A., Mesik, L., Ji, X., Fang, Q., Li, H.-F., Li, Y.-T., Zingg, B., Zhang, L. I., & Tao, H. W. (2016) · Neuron · doi:10.1016/j.neuron.2016.01.027 · Cited by 298
The Cellular Basis of GABA B -Mediated Interhemispheric Inhibition
Palmer, L. M., Schulz, J. M., Murphy, S. C., Ledergerber, D., Murayama, M., & Larkum, M. E. (2012) · Science · doi:10.1126/science.1217276 · Cited by 284
The GABAB1b Isoform Mediates Long-Lasting Inhibition of Dendritic Ca2+ Spikes in Layer 5 Somatosensory Pyramidal Neurons
Pérez‐Garci, E., Gassmann, M., Bettler, B., & Larkum, M. E. (2006) · Neuron · doi:10.1016/j.neuron.2006.04.019 · Cited by 262
Electrical synapses define networks of neocortical GABAergic neurons
Hestrin, S., & Galarreta, M. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.04.001 · Cited by 258
Self-citation
Classification of NPY-Expressing Neocortical Interneurons
Karagiannis, A., Gallopin, T., Dávid, C., Battaglia, D., Geoffroy, H., Rossier, J., Hillman, E. M. C., Staiger, J. F., & Cauli, B. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.0058-09.2009 · Cited by 256
Oscillations and Filtering Networks Support Flexible Routing of Information
Akam, T., & Kullmann, D. M. (2010) · Neuron · doi:10.1016/j.neuron.2010.06.019 · Cited by 245
Selective Coexpression of Multiple Chemical Markers Defines Discrete Populations of Neocortical GABAergic Neurons
Kubota, Y., Shigematsu, N., Karube, F., Sekigawa, A., Kato, S., Yamaguchi, N., Hirai, Y., Morishima, M., & Kawaguchi, Y. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq252 · Cited by 235
Prediction and memory: A predictive coding account
Barron, H. C., Auksztulewicz, R., & Friston, K. (2020) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2020.101821 · Cited by 220
Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons
Abs, E., Poorthuis, R. B., Apelblat, D., Muhammad, K., Pardi, M. B., Enke, L., Kushinsky, D., Pu, D.-L., Eizinger, M. F., Conzelmann, K., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.09.001 · Cited by 223
Thalamic control of layer 1 circuits in prefrontal cortex
Cruikshank, S. J., Ahmed, O. J., Stevens, T. R., Patrick, S. L., Gonzalez, A. N., Elmaleh, M., & Connors, B. W. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.3231-12.2012 · Cited by 212
Synchronization of Electrically Coupled Pairs of Inhibitory Interneurons in Neocortex
Mancilla, J. G., Lewis, T. J., Pinto, D. J., Rinzel, J., & Connors, B. W. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2715-06.2007 · Cited by 209
Electrical synapses coordinate activity in the suprachiasmatic nucleus
Long, M. A., Jutras, M. J., Connors, B. W., & Burwell, R. D. (2004) · Nature Neuroscience · doi:10.1038/nn1361 · Cited by 194
Anatomy and physiology of the thick-tufted layer 5 pyramidal neuron
Ramaswamy, S., & Markram, H. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00233 · Cited by 204
Four Unique Interneuron Populations Reside in Neocortical Layer 1
Schuman, B., Machold, R. P., Hashikawa, Y., Fuzik, J., Fishell, G. J., & Rudy, B. (2019) · The Journal of Neuroscience · doi:10.1523/jneurosci.1613-18.2018 · Cited by 184
“Previous studies of L1 INs agree that an important component of this population is neurogliaform cells (NGFCs), INs that mediate long-lasting GABAA and GABAB inhibition of PCs and have a late-spiking (LS) firing pattern when depolarized to near threshold membrane potentials (Chu et al., 2003; Tamás et al., 2003; Overs…”
BackgroundInfluential
Functional properties and projections of neurons in the medial amygdala
Keshavarzi, S., Sullivan, R. K. P., Ianno, D. J., & Sah, P. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1176-14.2014 · Cited by 176
Different transmitter transients underlie presynaptic cell type specificity of GABA A,slow and GABA A,fast
Szabadics, J., Tamás, G., & Soltesz, I. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0707204104 · Cited by 170
Gap-Junctional Coupling between Neurogliaform Cells and Various Interneuron Types in the Neocortex
Simon, A., Oláh, S., Molnár, G., Szabadics, J., & Tamás, G. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1431-05.2005 · Cited by 163
All-Optical Electrophysiology Reveals the Role of Lateral Inhibition in Sensory Processing in Cortical Layer 1
Fan, L. Z., Kheifets, S., Böhm, U. L., Wu, H., Piatkevich, K. D., Xie, M. E., Parot, V., Ha, Y., Evans, K. E., Boyden, E. S., et al. (2020) · Cell · doi:10.1016/j.cell.2020.01.001 · Cited by 160
Activity-Dependent Long-Term Depression of Electrical Synapses
Haas, J. S., Zavala, B., & Landisman, C. E. (2011) · Science · doi:10.1126/science.1207502 · Cited by 152
Neocortical Layer 1: an elegant solution to top-down and bottom-up integration
Schuman, B., Dellal, S., Prönneke, A., Machold, R., & Rudy, B. (2021) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-100520-012117 · Cited by 148
Serotonin 3A Receptor Subtype as an Early and Protracted Marker of Cortical Interneuron Subpopulations
Vucurovic, K., Gallopin, T., Ferezou, I., Rancillac, A., Chameau, P., van Hooft, J. A., Geoffroy, H., Monyer, H., Rossier, J., & Vitalis, T. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhp310 · Cited by 139
Cluster Analysis–Based Physiological Classification and Morphological Properties of Inhibitory Neurons in Layers 2–3 of Monkey Dorsolateral Prefrontal Cortex
Krimer, L. S., Zaitsev, A. V., Czanner, G., Kröner, S., González‐Burgos, G., Povysheva, N. V., Iyengar, S., Barrionuevo, G., & Lewis, D. A. (2005) · Journal of Neurophysiology · doi:10.1152/jn.00156.2005 · Cited by 135
Mediodorsal and Ventromedial Thalamus Engage Distinct L1 Circuits in the Prefrontal Cortex
Anastasiades, P. G., Collins, D. P., & Carter, A. G. (2020) · Neuron · doi:10.1016/j.neuron.2020.10.031 · Cited by 139
Prior expectations evoke stimulus-specific activity in the deep layers of the primary visual cortex
Aitken, F., Menelaou, G., Warrington, O., Koolschijn, R. S., Corbin, N., Callaghan, M. F., & Kok, P. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3001023 · Cited by 141
Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons
Miyoshi, G., Young, A., Petros, T., Karayannis, T., McKenzie Chang, M., Lavado, A., Iwano, T., Nakajima, M., Taniguchi, H., Huang, Z. J., et al. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.1164-15.2015 · Cited by 135
C. elegans AWA Olfactory Neurons Fire Calcium-Mediated All-or-None Action Potentials
Liu, Q., Kidd, P. B., Dobosiewicz, M., & Bargmann, C. I. (2018) · Cell · doi:10.1016/j.cell.2018.08.018 · Cited by 135
Lhx6 directly regulates Arx and CXCR7 to determine cortical interneuron fate and laminar position
Vogt, D., Hunt, R. F., Mandal, S., Sandberg, M., Silberberg, S. N., Nagasawa, T., Yang, Z., Baraban, S. C., & Rubenstein, J. L. R. (2014) · Neuron · doi:10.1016/j.neuron.2014.02.030 · Cited by 129
Specificity of synaptic connectivity between layer 1 inhibitory interneurons and layer 2/3 pyramidal neurons in the rat neocortex
Wozny, C., & Williams, S. R. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhq257 · Cited by 129
Dendritic Branch Typing and Spine Expression Patterns in Cortical Nonpyramidal Cells
Kawaguchi, Y., Karube, F., & Kubota, Y. (2005) · Cerebral Cortex · doi:10.1093/cercor/bhj015 · Cited by 125
Many specialists for suppressing cortical excitation
Burkhalter, A. (2008) · Frontiers in Neuroscience · doi:10.3389/neuro.01.026.2008 · Cited by 127
Regulation of cortical activity and arousal by the matrix cells of the ventromedial thalamic nucleus
Honjoh, S., Sasai, S., Schiereck, S. S., Nagai, H., Tononi, G., & Cirelli, C. (2018) · Nature Communications · doi:10.1038/s41467-018-04497-x · Cited by 118
Output of neurogliaform cells to various neuron types in the human and rat cerebral cortex
Oláh, S. (2007) · Frontiers in Neural Circuits · doi:10.3389/neuro.04.004.2007 · Cited by 118
Electrical Coupling among Irregular-Spiking GABAergic Interneurons Expressing Cannabinoid Receptors
Galarreta, M., Erdélyi, F., Szabó, G., & Hestrin, S. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3027-04.2004 · Cited by 122
Self-citation
Distinct GABAergic targets of feedforward and feedback connections between lower and higher areas of rat visual cortex
Gonchar, Y., & Burkhalter, A. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-34-10904.2003 · Cited by 114
Traumatic Brain Injury and Neuronal Functionality Changes in Sensory Cortex
Carron, S. F., Alwis, D. S., & Rajan, R. (2016) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2016.00047 · Cited by 115
Gi/o-Protein Coupled Receptors in the Aging Brain
de Oliveira, P. G., Ramos, M. L., Amaro, A. J. M., Dias, R. A., & Vieira, S. I. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00089 · Cited by 111
Canonical Organization of Layer 1 Neuron-Led Cortical Inhibitory and Disinhibitory Interneuronal Circuits
Lee, A. J., Wang, G., Jiang, X., Johnson, S. M., Hoang, E. T., Lanté, F., Stornetta, R. L., Beenhakker, M. P., Shen, Y., & Julius Zhu, J. (2015) · Cerebral Cortex · doi:10.1093/cercor/bhu020 · Cited by 94
Distinctive Classes of GABAergic Interneurons Provide Layer-Specific Phasic Inhibition in the Anterior Piriform Cortex
Suzuki, N., & Bekkers, J. M. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhq046 · Cited by 92
Electrical Coupling between Interneurons with Different Excitable Properties in the Stratum Lacunosum-Moleculare of the Juvenile CA1 Rat Hippocampus
Zsiros, V., & Maccaferri, G. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2810-05.2005 · Cited by 88
Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex
Chartrand, T., Dalley, R., Close, J., Goriounova, N. A., Lee, B. R., Mann, R., Miller, J. A., Molnar, G., Mukora, A., Alfiler, L., et al. (2023) · Science · doi:10.1126/science.adf0805 · Cited by 88
Activity-Dependent Modulation of Layer 1 Inhibitory Neocortical Circuits by Acetylcholine
Brombas, A., Fletcher, L. N., & Williams, S. R. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.4470-13.2014 · Cited by 90
Retrograde tracing with recombinant rabies virus reveals correlations between projection targets and dendritic architecture in layer 5 of mouse barrel cortex
Larsen, D. D. (2008) · Frontiers in Neural Circuits · doi:10.3389/neuro.04.005.2007 · Cited by 86
Involvement of gap junctions in the development of the neocortex
Sutor, B., & Hagerty, T. (2005) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2005.09.005 · Cited by 85
Rapid Arrival and Integration of Ascending Sensory Information in Layer 1 Nonpyramidal Neurons and Tuft Dendrites of Layer 5 Pyramidal Neurons of the Neocortex
Zhu, Y., & Zhu, J. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4805-03.2004 · Cited by 85
Production and organization of neocortical interneurons
Sultan, K. T., Brown, K. N., & Shi, S.-H. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00221 · Cited by 83
Abrupt Maturation of a Spike-Synchronizing Mechanism in Neocortex
Long, M. A., Cruikshank, S. J., Jutras, M. J., & Connors, B. W. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0375-05.2005 · Cited by 83
Inhibitory Regulation of Dendritic Activity in vivo
Palmer, L. M., Murayama, M., & Larkum, M. E. (2012) · Frontiers in Neural Circuits · doi:10.3389/fncir.2012.00026 · Cited by 88
Astrocytes are a key conduit for upstream signaling of vasodilation during cerebral cortical neuronal activation in vivo
Xu, H., Mao, L., Ye, S., Paisansathan, C., Vetri, F., & Pelligrino, D. A. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00530.2007 · Cited by 82
Mechanisms Generating Dual-Component Nicotinic EPSCs in Cortical Interneurons
Bennett, C., Arroyo, S., Berns, D. S., & Hestrin, S. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.3565-12.2012 · Cited by 80
Self-citation
Locomotor rhythm maintenance: electrical coupling among premotor excitatory interneurons in the brainstem and spinal cord of young Xenopus tadpoles
Li, W., Roberts, A., & Soffe, S. R. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2008.166942 · Cited by 80
Differential Expression ofIAChannel Subunits Kv4.2 and Kv4.3 in Mouse Visual Cortical Neurons and Synapses
Burkhalter, A., Gonchar, Y., Mellor, R. L., & Nerbonne, J. M. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2599-06.2006 · Cited by 79
Functional diversity of supragranular GABAergic neurons in the barrel cortex
Gentet, L. J. (2012) · Frontiers in Neural Circuits · doi:10.3389/fncir.2012.00052 · Cited by 83
Rapid Neuromodulation of Layer 1 Interneurons in Human Neocortex
Poorthuis, R. B., Muhammad, K., Wang, M., Verhoog, M. B., Junek, S., Wrana, A., Mansvelder, H. D., & Letzkus, J. J. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.03.111 · Cited by 73
Cell-type identity: a key to unlocking the function of neocortical circuits
Brown, S. P., & Hestrin, S. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.07.011 · Cited by 70
Self-citation
Altered Prefrontal Excitation/Inhibition Balance and Prefrontal Output: Markers of Aging in Human Memory Networks
Legon, W., Punzell, S., Dowlati, E. P., Adams, S. E., Stiles, A. B., & Moran, R. (2015) · Cerebral Cortex · doi:10.1093/cercor/bhv200 · Cited by 69
Electrophysiological Differences Between Neurogliaform Cells From Monkey and Rat Prefrontal Cortex
Povysheva, N. V., Zaitsev, A. V., Kröner, S., Krimer, O. A., Rotaru, D. C., González‐Burgos, G., Lewis, D. A., & Krimer, L. S. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00794.2006 · Cited by 68
Truncated TrkB‐T1 regulates the morphology of neocortical layer I astrocytes in adult rat brain slices
Ohira, K., Funatsu, N., Homma, K. J., Sahara, Y., Hayashi, M., Kaneko, T., & Nakamura, S. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05282.x · Cited by 68
Synaptic and cellular organization of layer 1 of the developing rat somatosensory cortex
Muralidhar, S., Wang, Y., & Markram, H. (2014) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2013.00052 · Cited by 71
Extensive overlap of mu-opioid and nicotinic sensitivity in cortical interneurons
Ferezou, I., Hill, E. L., Cauli, B., Gibelin, N., Kaneko, T., Rossier, J., & Lambolez, B. (2007) · Cerebral Cortex · doi:10.1093/cercor/bhl104 · Cited by 65
Cholinergic circuit modulation through differential recruitment of neocortical interneuron types during behaviour
Poorthuis, R. B., Enke, L., & Letzkus, J. J. (2014) · The Journal of Physiology · doi:10.1113/jphysiol.2014.273862 · Cited by 66
Role of Interneuron Diversity in the Cortical Microcircuit for Attention
Buia, C., & Tiesinga, P. H. E. (2008) · Journal of Neurophysiology · doi:10.1152/jn.01004.2007 · Cited by 64
Physiologic Regulation of a Tetrodotoxin-Sensitive Sodium Influx That Mediates a Slow Afterdepolarization Potential in Gonadotropin-Releasing Hormone Neurons: Possible Implications for the Central Regulation of Fertility
Chu, Z., & Moenter, S. M. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3171-06.2006 · Cited by 62
Self-citation
Gap junction plasticity as a mechanism to regulate network-wide oscillations
Pernelle, G., Nicola, W., & Clopath, C. (2018) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1006025 · Cited by 60
Initiation of electrographic seizures by neuronal networks in entorhinal and perirhinal cortices in vitro
Guzman, P. D., D’Antuono, M., & Avoli, M. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2003.11.013 · Cited by 60
Development of Layer 1 Neurons in the Mouse Neocortex
Ma, J., Yao, X.-H., Fu, Y., & Yu, Y. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht114 · Cited by 62
The Potential Role of Gap Junctional Plasticity in the Regulation of State
Coulon, P., & Landisman, C. E. (2017) · Neuron · doi:10.1016/j.neuron.2017.02.041 · Cited by 57
Properties of external plexiform layer interneurons in mouse olfactory bulb slices
Hamilton, K. A., Heinbockel, T., Ennis, M. J., Szabó, G., Erdélyi, F., & Hayar, A. M. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.03.008 · Cited by 57
Expression of Gap Junction Protein Connexin36 in Multiple Subtypes of GABAergic Neurons in Adult Rat Somatosensory Cortex
Ma, Y., Hioki, H., Konno, M., Pan, S., Nakamura, H., Nakamura, K., Furuta, T., Li, J., & Kaneko, T. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr051 · Cited by 55
Cooperative Activation of D1and D2Dopamine Receptors Enhances a Hyperpolarization-Activated Inward Current in Layer I Interneurons
Wu, J., & Hablitz, J. J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1405-05.2005 · Cited by 55
Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells
Chittajallu, R., Auville, K., Mahadevan, V., Lai, M., Hunt, S., Calvigioni, D., Pelkey, K. A., Zaghloul, K. A., & McBain, C. J. (2020) · eLife · doi:10.7554/elife.57571 · Cited by 54
Changes in Calcium-Binding Protein Expression in Human Cortical Contusion Tissue
Buriticá, E., Villamil, L., Guzmán, F., Escobar, M. I., Garcia‐Cairasco, N., & Pimienta, H. J. (2009) · Journal of Neurotrauma · doi:10.1089/neu.2009.0894 · Cited by 50
Generation of diverse cortical inhibitory interneurons
Sultan, K. T., & Shi, S. (2017) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.306 · Cited by 57
Structural Organization of the Gap Junction Network in the Cerebral Cortex
Fukuda, T. (2007) · The Neuroscientist · doi:10.1177/1073858406296760 · Cited by 49
Bistable Network Behavior of Layer I Interneurons in Auditory Cortex
Merriam, E. B., Netoff, T. I., & Banks, M. I. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0512-05.2005 · Cited by 47
GABAergic Inhibitory Interneurons in the Posterior Piriform Cortex of the GAD67-GFP Mouse
Young, A., & Sun, Q. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp072 · Cited by 43
Integration of Synaptic Responses to Neighboring Whiskers in Rat Barrel Cortex In Vivo
Higley, M. J., & Contreras, D. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00917.2004 · Cited by 43
Properties of precise firing synchrony between synaptically coupled cortical interneurons depend on their mode of coupling
Hu, H., & Agmon, A. (2015) · Journal of Neurophysiology · doi:10.1152/jn.00304.2015 · Cited by 48
In vivo evidence for the involvement of the carboxy terminal domain in assembling connexin 36 at the electrical synapse
Helbig, I., Sammler, E. M., Eliava, M., Bolshakov, A. P., Rozov, A. V., Bruzzone, R., Monyer, H., & Hormuzdi, S. G. (2010) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2010.05.008 · Cited by 40
Neocortex
Kirkcaldie, M. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-369497-3.10004-4 · Cited by 45
Ectopic action potential generation in cortical interneurons during synchronized GABA responses
Keros, S., & Hablitz, J. J. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.12.010 · Cited by 40
Connexon connexions in the thalamocortical system
Cruikshank, S. J., Landisman, C. E., Mancilla, J. G., & Connors, B. W. (2005) · Progress in brain research · doi:10.1016/s0079-6123(05)49004-4 · Cited by 36
Cellular and subcellular rat brain spermidine synthase expression patterns suggest region‐specific roles for polyamines, including cerebellar pre‐synaptic function
Krauss, M. I., Weiss, T., Langnaese, K., Richter, K., Kowski, A. B., Veh, R. W., & Laube, G. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04770.x · Cited by 37
Electrical coupling regulates layer 1 interneuron microcircuit formation in the neocortex
Yao, X.-H., Wang, M., He, X.-N., He, F., Zhang, S.-Q., Lu, W., Qiu, Z., & Yu, Y. (2016) · Nature Communications · doi:10.1038/ncomms12229 · Cited by 36
Control of Somatosensory Cortical Processing by Thalamic Posterior Medial Nucleus: A New Role of Thalamus in Cortical Function
Castejon, C., Barros-Zulaica, N., & Núñez, Á. (2016) · PLoS ONE · doi:10.1371/journal.pone.0148169 · Cited by 38

Authors: Chu, Z., Galarreta, M., & Hestrin, S.
Affiliations: Stanford Medicine (US)
Venue: The Journal of Neuroscience
Publisher: Society for Neuroscience
Published: 2003-01-01
Volume: 23
Issue: 1
Pages: 96-102
ISSN: 0270-6474 (ISSN-L)
1529-2401
DOI: 10.1523/jneurosci.23-01-00096.2003
PMC: PMC6742162
OpenAlex: W2171308715
Semantic Scholar: 02a53e21726fd337b87f5d80b53b76713176c7e6
Cited by: 172
References: 38
Citations by year: 2026: 3 · 2025: 3 · 2024: 4 · 2023: 2 · 2022: 5 · 2021: 1 · 2020: 8 · 2019: 4 · 2018: 11 · 2017: 6 · 2016: 10 · 2015: 8 · 2014: 10 · 2013: 6 · 2012: 16
FWCI: 3.81
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Neuroscience (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Eye Institute (R01EY012114, EY12114, EY09120, R01EY009120)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Connexins and lens biology
Keywords: GABAergic interneurons, electrical coupling, synaptic integration, pyramidal neurons, layer 2/3, inhibitory interneurons, postsynaptic targets, paired recordings
MeSH terms: Animals, Cells, Cultured, Electric Conductivity, gamma-Aminobutyric Acid, Kinetics, Neural Inhibition, Neural Pathways, Synaptic Transmission, Neurons, Rats, Sprague-Dawley, Pyramidal Cells, Patch-Clamp Techniques, Neocortex, Excitatory Postsynaptic Potentials, Rats

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Synaptic Interactions of Late-Spiking Neocortical Neurons in Layer 1

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks