Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion

Glutamate uptake

Danbolt, N. C. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00067-8 · Cited by 4,068 · see citing works

Membrane vesicles as conveyors of immune responses

Théry, C., Ostrowski, M., & Segura, É. (2009) · Nature reviews. Immunology · doi:10.1038/nri2567 · Cited by 3,887 · see citing works

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

Trajković, K., Hsu, C., Chiantia, S., Rajendran, L., Wenzel, D., Wieland, F., Schwille, P., Brügger, B., & Simons, M. (2008) · Science · doi:10.1126/science.1153124 · Cited by 3,639 · see citing works

The Classical Complement Cascade Mediates CNS Synapse Elimination

Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., Micheva, K. D., Mehalow, A. K., Huberman, A. D., Stafford, B., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.036 · Cited by 3,313 · see citing works

SNAP receptors implicated in vesicle targeting and fusion

Söllner, T. H., Whiteheart, S. W., Brunner, M., Erdjument‐Bromage, H., Geromanos, S. J., Tempst, P., & Rothman, J. E. (1993) · Nature · doi:10.1038/362318a0 · Cited by 3,239 · see citing works

Rab27a and Rab27b control different steps of the exosome secretion pathway

Ostrowski, M., Carmo, N., Krumeich, S., Fanget, I., Raposo, G., Savina, A., Moita, C. F., Schauer, K., Hume, A. N., Freitas, R. P., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb2000 · Cited by 2,761 · see citing works

SNAREs — engines for membrane fusion

Jahn, R., & Scheller, R. H. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2002 · Cited by 2,635 · see citing works

Exosomes: Extracellular organelles important in intercellular communication

Mathivanan, S., Ji, H. L., & Simpson, R. J. (2010) · Journal of Proteomics · doi:10.1016/j.jprot.2010.06.006 · Cited by 2,539 · see citing works

SNAREpins: Minimal Machinery for Membrane Fusion

Weber, T., Zemelman, B. V., McNew, J. A., Westermann, B., Gmachl, M., Parlati, F., Söllner, T. H., & Rothman, J. E. (1998) · Cell · doi:10.1016/s0092-8674(00)81404-x · Cited by 2,481 · see citing works

Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution

Sutton, R. B., Fasshauer, D., Jahn, R., & Brunger, A. T. (1998) · Nature · doi:10.1038/26412 · Cited by 2,417 · cited 1× · see citing works

Molecular anatomy of a trafficking organelle

Takamori, S., Holt, M., Stenius, K., Lemke, E. A., Grønborg, M., Riedel, D., Urlaub, H., Schenck, S., Brügger, B., Ringler, P., et al. (2006) · Cell · doi:10.1016/j.cell.2006.10.030 · Cited by 2,373 · see citing works

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

Baietti, M. F., Zhang, Z., Mortier, E., Melchior, A., Degeest, G., Geeraerts, A., Ivarsson, Y., Depoortere, F., Coomans, C., Vermeiren, E., et al. (2012) · Nature Cell Biology · doi:10.1038/ncb2502 · Cited by 1,899 · see citing works

Glutamate Induces Calcium Waves in Cultured Astrocytes: Long-Range Glial Signaling

Cornell-Bell, A. H., Finkbeiner, S. M., Cooper, M. S., & Smith, S. J. (1990) · Science · doi:10.1126/science.1967852 · Cited by 1,846 · see citing works

Neurotrophins as synaptic modulators

Poo, M.-M. (2001) · Nature Reviews Neuroscience · doi:10.1038/35049004 · Cited by 1,775 · see citing works

Classification, Functions, and Clinical Relevance of Extracellular Vesicles

van der Pol, E., Böing, A. N., Harrison, P., Sturk, A., & Nieuwland, R. (2012) · Pharmacological Reviews · doi:10.1124/pr.112.005983 · Cited by 1,756 · see citing works

Glutamate-mediated astrocyte–neuron signalling

Parpura, V., Basarsky, T. A., Liu, F., Jeftinija, K., Jeftinija, S., & Haydon, P. G. (1994) · Nature · doi:10.1038/369744a0 · Cited by 1,737 · see citing works

Specialized Membrane Domains for Water Transport in Glial Cells: High-Resolution Immunogold Cytochemistry of Aquaporin-4 in Rat Brain

Nielsen, S. M., Nagelhus, E. A., Amiry-Moghaddam, M. R., Bourque, C. W., Agre, P. C., & Ottersen, O. P. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-01-00171.1997 · Cited by 1,440 · see citing works

Ectosomes and exosomes: shedding the confusion between extracellular vesicles

Cocucci, E., & Meldolesi, J. (2015) · Trends in Cell Biology · doi:10.1016/j.tcb.2015.01.004 · Cited by 1,435 · see citing works

Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

Burda, J. E., & Sofroniew, M. V. (2014) · Neuron · doi:10.1016/j.neuron.2013.12.034 · Cited by 1,431 · see citing works

Long-term potentiation depends on release of d-serine from astrocytes

Henneberger, C., Papouin, T., Oliet, S. H. R., & Rusakov, D. A. (2010) · Nature · doi:10.1038/nature08673 · Cited by 1,389 · see citing works

The yin and yang of neurotrophin action

Lu, B., Pang, P. T., & Woo, N. H. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1726 · Cited by 1,356 · see citing works

Complex archaea that bridge the gap between prokaryotes and eukaryotes

Spang, A., Saw, J. H., Jørgensen, S. L., Zaremba-Niedzwiedzka, K., Martijn, J., Lind, A. E., van Eijk, R., Schleper, C., Guy, L., & Ettema, T. J. G. (2015) · Nature · doi:10.1038/nature14447 · Cited by 1,324 · see citing works

Astrocytic Purinergic Signaling Coordinates Synaptic Networks

Pascual, O., Casper, K. B., Kubera, C., Zhang, J., Revilla-Sanchez, R., Sul, J.-Y., Takano, H., Moss, S. J., McCarthy, K., & Haydon, P. G. (2005) · Science · doi:10.1126/science.1116916 · Cited by 1,280 · see citing works

Guanylyl Cyclases and Signaling by Cyclic GMP

Lucas, K. A., Pitari, G. M., Kazerounian, S., Ruiz‐Stewart, I., Park, J. Y., Schulz, S., Chepenik, K. P., & Waldman, S. A. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01457-1 · Cited by 1,229 · see citing works

Astrocyte barriers to neurotoxic inflammation

Sofroniew, M. V. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3898 · Cited by 1,202 · see citing works

Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs

Fasshauer, D., Sutton, R. B., Brünger, A. T., & Jahn, R. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.26.15781 · Cited by 1,055 · see citing works

Cytology & cellular pathology of the nervous system

Penfield, W. G. (1965) · Medical Entomology and Zoology · Cited by 1,035 · see citing works

Natriuretic Peptides, Their Receptors, and Cyclic Guanosine Monophosphate-Dependent Signaling Functions

Potter, L. R., Abbey‐Hosch, S. E., & Dickey, D. M. (2005) · Endocrine Reviews · doi:10.1210/er.2005-0014 · Cited by 1,004 · see citing works

Secretory Granule Exocytosis

Burgoyne, R. D., & Morgan, A. (2003) · Physiological Reviews · doi:10.1152/physrev.00031.2002 · Cited by 934 · see citing works

Exosomes: A Common Pathway for a Specialized Function

van Niel, G., Porto-Carreiro, I., Simoes, S., & Raposo, G. (2006) · The Journal of Biochemistry · doi:10.1093/jb/mvj128 · Cited by 922 · see citing works

Astrocytic Modulation of Sleep Homeostasis and Cognitive Consequences of Sleep Loss

Halassa, M. M., Florian, C., Fellin, T., Munoz, J. R., Lee, S.-Y., Abel, T. G., Haydon, P. G., & Frank, M. G. (2009) · Neuron · doi:10.1016/j.neuron.2008.11.024 · Cited by 877 · see citing works

Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

Hsu, C., Morohashi, Y., Yoshimura, S., Manrique‐Hoyos, N., Jung, S., Lauterbach, M. A., Bakhti, M., Grønborg, M., Möbius, W., Rhee, J., et al. (2010) · The Journal of Cell Biology · doi:10.1083/jcb.200911018 · Cited by 860 · see citing works

D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release

Schell, M. J., Molliver, M. E., & Snyder, S. H. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.9.3948 · Cited by 832 · see citing works

Glutamate exocytosis from astrocytes controls synaptic strength

Jourdain, P., Bergersen, L. H., Bhaukaurally, K., Bezzi, P., Santello, M., Domercq, M., Matute, C., Tonello, F., Gundersen, V., & Volterra, A. (2007) · Nature Neuroscience · doi:10.1038/nn1849 · Cited by 806 · see citing works

Microparticles

Mause, S. F., & Weber, C. (2010) · Circulation Research · doi:10.1161/circresaha.110.226456 · Cited by 787 · see citing works

A lipid associated with the antiphospholipid syndrome regulates endosome structure and function

Kobayashi, T., Stang, E., Fang, K. S., de Moerloose, P., Parton, R. G., & Gruenberg, J. (1998) · Nature · doi:10.1038/32440 · Cited by 787 · see citing works

Intracellular calcium dependence of transmitter release rates at a fast central synapse

Schneggenburger, R., & Neher, E. (2000) · Nature · doi:10.1038/35022702 · Cited by 785 · see citing works

Connexins regulate calcium signaling by controlling ATP release

Cotrina, M. L., Lin, J. H.-C., Alves‐Rodrigues, A., Liu, S., Li, J., Azmi, H., Kang, J., Naus, C. C. G., & Nedergaard, M. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.26.15735 · Cited by 773 · see citing works

Astrocytes present myelin basic protein to encephalitogenic T-cell lines

Fontana, A., Fierz, W., & Wekerle, H. (1984) · Nature · doi:10.1038/307273a0 · Cited by 771 · see citing works

Physiological Roles of Aquaporin-4 in Brain

Nagelhus, E. A., & Ottersen, O. P. (2013) · Physiological Reviews · doi:10.1152/physrev.00011.2013 · Cited by 766 · see citing works

Aquaporin‐4 facilitates reabsorption of excess fluid in vasogenic brain edema

Papadopoulos, M. C., Manley, G. T., Krishna, S., & Verkman, A. S. (2004) · The FASEB Journal · doi:10.1096/fj.04-1723fje · Cited by 749 · see citing works

Calcium dependence of the rate of exocytosis in a synaptic terminal

Heidelberger, R., Heinemann, C., Neher, E., & Matthews, G. (1994) · Nature · doi:10.1038/371513a0 · Cited by 746 · see citing works

Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate

Bezzi, P., Gundersen, V., Galbete, J. L., Seifert, G., Steinhäuser, C., Pilati, E., & Volterra, A. (2004) · Nature Neuroscience · doi:10.1038/nn1246 · Cited by 737 · see citing works

Astrocytes Potentiate Transmitter Release at Single Hippocampal Synapses

Perea, G., & Araque, A. (2007) · Science · doi:10.1126/science.1144640 · Cited by 727 · see citing works

Sweet Sixteen for ANLS

Pellerin, L., & Magistretti, P. J. (2011) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2011.149 · Cited by 726 · see citing works

Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

Nabhan, J. F., Hu, R., Oh, R. S., Cohen, S. N., & Lu, Q. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1200448109 · Cited by 722 · see citing works

NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s Disease

Lian, H., Yang, L., Cole, A., Sun, L., Chiang, A. C.-A., Fowler, S. W., Shim, D. J., Rodriguez-Rivera, J., Taglialatela, G., Jankowsky, J. L., et al. (2015) · Neuron · doi:10.1016/j.neuron.2014.11.018 · Cited by 697 · see citing works

Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures

Kimelberg, H., Goderie, S., Higman, S., Pang, S., & Waniewski, R. (1990) · The Journal of Neuroscience · doi:10.1523/jneurosci.10-05-01583.1990 · Cited by 690 · see citing works

Do astrocytes really exocytose neurotransmitters?

Hamilton, N. B., & Attwell, D. (2010) · Nature reviews. Neuroscience · doi:10.1038/nrn2803 · Cited by 674 · see citing works

The dual role of astrocyte activation and reactive gliosis

Pekny, M., Wilhelmsson, U., & Pekna, M. (2014) · Neuroscience Letters · doi:10.1016/j.neulet.2013.12.071 · Cited by 666 · see citing works

Astrocytes and Glioblastoma cells release exosomes carrying mtDNA

Guescini, M., Genedani, S., Stocchi, V., & Agnati, L. F. (2009) · Journal of Neural Transmission · doi:10.1007/s00702-009-0288-8 · Cited by 662 · see citing works

Subunit-specific temporal and spatial patterns of AMPA receptor exocytosis in hippocampal neurons

Passafaro, M., Piëch, V., & Sheng, M. (2001) · Nature Neuroscience · doi:10.1038/nn0901-917 · Cited by 655 · see citing works

Astrocyte-Derived ATP Induces Vesicle Shedding and IL-1β Release from Microglia

Bianco, F., Pravettoni, E., Colombo, A., Schenk, U., Möller, T., Matteoli, M., & Verderio, C. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.11.7268 · Cited by 596 · see citing works

Adenosine and sleep–wake regulation

Basheer, R., Strecker, R. E., Thakkar, M. M., & McCarley, R. W. (2004) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2004.06.004 · Cited by 589 · see citing works

Endocannabinoids Mediate Neuron-Astrocyte Communication

Navarrete, M., & Araque, A. (2008) · Neuron · doi:10.1016/j.neuron.2008.01.029 · Cited by 588 · see citing works

The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate

Fremeau, R. T., Burman, J. L., Qureshi, T., Tran, C. H., Proctor, J. M., Johnson, J., Zhang, H., Sulzer, D. L., Copenhagen, D. R., Storm‐Mathisen, J., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.222546799 · Cited by 568 · see citing works

Nonclassical IL-1β Secretion Stimulated by P2X7 Receptors Is Dependent on Inflammasome Activation and Correlated with Exosome Release in Murine Macrophages

Qu, Y., Franchi, L., Nunez, G., & Dubyak, G. R. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.3.1913 · Cited by 563 · see citing works

Regulated ATP release from astrocytes through lysosome exocytosis

Zhang, Z., Chen, G., Zhou, W., Song, A., Xu, T., Luo, Q., Wang, W., Gu, X., & Duan, S. (2007) · Nature Cell Biology · doi:10.1038/ncb1620 · Cited by 525 · see citing works

P2X 7 Receptors Mediate ATP Release and Amplification of Astrocytic Intercellular Ca 2+ Signaling

Suadicani, S. O., Brosnan, C. F., & Scemes, E. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3902-05.2006 · Cited by 512 · see citing works

Calcium Sensitivity of Glutamate Release in a Calyx-Type Terminal

Bollmann, J. H., Sakmann, B. J., & Borst, J. G. G. (2000) · Science · doi:10.1126/science.289.5481.953 · Cited by 507 · see citing works

Calcium Control of Neurotransmitter Release

Sudhof, T. C. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a011353 · Cited by 502 · see citing works

Nanodomain coupling between Ca2+ channels and sensors of exocytosis at fast mammalian synapses

Eggermann, E., Bucurenciu, I., Goswami, S. P., & Jonas, P. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3125 · Cited by 500 · see citing works

Storage and Release of ATP from Astrocytes in Culture

Coco, S., Calegari, F., Pravettoni, E., Pozzi, D., Taverna, E., Rosa, P., Matteoli, M., & Verderio, C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m209454200 · Cited by 492 · see citing works

Glutamate receptor activation triggers a calcium-dependent and SNARE protein-dependent release of the gliotransmitter D-serine

Mothet, J., Pollegioni, L., Ouanounou, G., Martineau, M., Fossier, P., & Baux, G. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408483102 · Cited by 461 · see citing works

The phagosome: compartment with a license to kill

Haas, A. (2007) · Traffic · doi:10.1111/j.1600-0854.2006.00531.x · Cited by 450 · see citing works

Aquaporin-4 Water Channel Protein in the Rat Retina and Optic Nerve: Polarized Expression in Müller Cells and Fibrous Astrocytes

Nagelhus, E. A., Veruki, M. L., Torp, R., Haug, F. Š., Laake, J. H., Nielsen, S. M., Agre, P. C., & Ottersen, O. P. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-07-02506.1998 · Cited by 449 · see citing works

Rab7 Regulates Late Endocytic Trafficking Downstream of Multivesicular Body Biogenesis and Cargo Sequestration

Vanlandingham, P. A., & Ceresa, B. P. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m809277200 · Cited by 441 · see citing works

Complement and Its Receptors: New Insights into Human Disease

Holers, V. M. (2014) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032713-120154 · Cited by 430 · see citing works

Identification of a vesicular nucleotide transporter

Sawada, K., Echigo, N., Juge, N., Miyaji, T., Otsuka, M., Omote, H., Yamamoto, A., & Moriyama, Y. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800141105 · Cited by 418 · see citing works

Human Astrocytes: Secretome Profiles of Cytokines and Chemokines

Choi, S. S., Lee, H. J., Lim, I., Satoh, J., & Kim, S. U. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092325 · Cited by 411 · see citing works

Membrane proximal lysosomes are the major vesicles responsible for calcium-dependent exocytosis in nonsecretory cells

Jaiswal, J. K., Andrews, N. W., & Simon, S. M. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200208154 · Cited by 389 · see citing works

The glutamate‐glutamine cycle is not stoichiometric: Fates of glutamate in brain

McKenna, M. C. (2007) · Journal of Neuroscience Research · doi:10.1002/jnr.21444 · Cited by 385 · see citing works

TNFα Controls Glutamatergic Gliotransmission in the Hippocampal Dentate Gyrus

Santello, M., Bezzi, P., & Volterra, A. (2011) · Neuron · doi:10.1016/j.neuron.2011.02.003 · Cited by 368 · see citing works

Gliotransmission: Exocytotic release from astrocytes

Parpura, V., & Zorec, R. (2009) · Brain Research Reviews · doi:10.1016/j.brainresrev.2009.11.008 · Cited by 367 · see citing works

Vesicular Glutamate Transporter-Dependent Glutamate Release from Astrocytes

Montana, V., Ni, Y., Sunjara, V., Hua, X. J., & Parpura, V. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3770-03.2004 · Cited by 363 · see citing works

Astrocytes Secrete Exosomes Enriched with Proapoptotic Ceramide and Prostate Apoptosis Response 4 (PAR-4)

Wang, G., Dinkins, M. B., He, Q., Zhu, G., Poirier, C., Campbell, A., Mayer‐Pröschel, M., & Bieberich, E. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.340513 · Cited by 356 · see citing works

Mechanisms of glutamate release from astrocytes

Malarkey, E. B., & Parpura, V. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.06.005 · Cited by 356 · see citing works

Neuropeptide Y functions as a neuroproliferative factor

Hansel, D. E., Eipper, B. A., & Ronnett, G. V. (2001) · Nature · doi:10.1038/35073601 · Cited by 350 · see citing works

GABA and Glutamate Transporters in Brain

Zhou, Y., & Danbolt, N. C. (2013) · Frontiers in Endocrinology · doi:10.3389/fendo.2013.00165 · Cited by 347 · see citing works

Lactate-mediated glia-neuronal signalling in the mammalian brain

Tang, F., Lane, S., KORSAK, A. S., Paton, J. F. R., Gourine, A. V., Kasparov, S., & Teschemacher, A. G. (2014) · Nature Communications · doi:10.1038/ncomms4284 · Cited by 336 · see citing works

Vesicular transmitter release from astrocytes

Montana, V., Malarkey, E. B., Verderio, C., Matteoli, M., & Parpura, V. (2006) · Glia · doi:10.1002/glia.20367 · Cited by 325 · see citing works

TRPA1 Channels Are Regulators of Astrocyte Basal Calcium Levels and Long-Term Potentiation via Constitutive D-Serine Release

Shigetomi, E., Jackson‐Weaver, O., Huckstepp, R. T. R., O’Dell, T. J., & Khakh, B. S. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.5779-12.2013 · Cited by 322 · see citing works

Capacitance steps and fusion pores of small and large-dense-core vesicles in nerve terminals

Klyachko, V. A., & Jackson, M. B. (2002) · Nature · doi:10.1038/nature00852 · Cited by 294 · see citing works

Synaptic Integration of Adult-Born Hippocampal Neurons Is Locally Controlled by Astrocytes

Sultan, S., Li, L., Moss, J., Petrelli, F., Cassé, F., Gebara, E., Lopatar, J., Pfrieger, F. W., Bezzi, P., Bischofberger, J., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.10.037 · Cited by 284 · see citing works

Exocytosis of ATP From Astrocytes Modulates Phasic and Tonic Inhibition in the Neocortex

Lalo, U., Palygin, O., Rasooli-Nejad, S., Andrew, J., Haydon, P. G., & Pankratov, Y. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1001747 · Cited by 270 · see citing works

Glutamate transporters bring competition to the synapse

Huang, Y. H., & Bergles, D. E. (2004) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2004.05.007 · Cited by 269 · see citing works

Regulation of heat shock protein 70 release in astrocytes: Role of signaling kinases

Taylor, A. R., Robinson, M., Gifondorwa, D. J., Tytell, M., & Milligan, C. E. (2007) · Developmental Neurobiology · doi:10.1002/dneu.20559 · Cited by 261 · see citing works

Fast Exocytosis with Few Ca2+ Channels in Insulin-Secreting Mouse Pancreatic B Cells

Barg, S., Ma, X., Eliasson, L., Galvanovskis, J., Göpel, S. O., Obermüller, S., Platzer, J., Renström, E., Trus, M., Atlas, D., et al. (2001) · Biophysical Journal · doi:10.1016/s0006-3495(01)75964-4 · Cited by 255 · see citing works

Fusion-related Release of Glutamate from Astrocytes

Zhang, Q., Pangršič, T., Kreft, M., Kržan, M., Li, N., Sul, J., Halassa, M. M., Bockstaele, E. V., Zorec, R., & Haydon, P. G. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312845200 · Cited by 246 · see citing works

Exocytotic Release of ATP from Cultured Astrocytes

Pangršič, T., Potokar, M., Stenovec, M., Kreft, M., Fabbretti, E., Nistri, A., Pryazhnikov, E., Khiroug, L. S., Giniatullin, R. A., & Zorec, R. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700290200 · Cited by 245 · see citing works

A low affinity Ca2+ receptor controls the final steps in peptide secretion from pituitary melanotrophs

Thomas, P., Wong, J. G., Lee, A. K., & Almers, W. (1993) · Neuron · doi:10.1016/0896-6273(93)90274-u · Cited by 244 · see citing works

Dissection of Three Ca 2+ -Dependent Steps Leading to Secretion in Chromaffin Cells from Mouse Adrenal Slices

Voets, T. (2000) · Neuron · doi:10.1016/s0896-6273(00)00131-8 · Cited by 242 · see citing works

The Glutamate–Glutamine (GABA) Cycle: Importance of Late Postnatal Development and Potential Reciprocal Interactions between Biosynthesis and Degradation

Hertz, L. (2013) · Frontiers in Endocrinology · doi:10.3389/fendo.2013.00059 · Cited by 235 · see citing works

The central nervous system as an immunocompetent organ: role of glial cells in antigen presentation

Shrikant, P., & Benveniste, E. N. (1996) · The Journal of Immunology · doi:10.4049/jimmunol.157.5.1819 · Cited by 233 · see citing works

Endogenous nonneuronal modulators of synaptic transmission control cortical slow oscillations in vivo

Fellin, T., Halassa, M. M., Terunuma, M., Succol, F., Takano, H., Frank, M., Moss, S. J., & Haydon, P. G. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906419106 · Cited by 227 · see citing works

Localization of estrogen receptor ?-immunoreactivity in astrocytes of the adult rat brain

Azcoitia, Í., Sierra, A., & García‐Segura, L. M. (1999) · Glia · doi:10.1002/(sici)1098-1136(199905)26:3 · Cited by 222 · see citing works

Lysobisphosphatidic Acid Controls Endosomal Cholesterol Levels

Chevallier, J., Chamoun, Z., Jiang, G., Prestwich, G. D., Sakai, N., Matile, S., Parton, R. G., & Gruenberg, J. E. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m801463200 · Cited by 220 · see citing works

Drowning stars: reassessing the role of astrocytes in brain edema

Thrane, A. S., Thrane, V. R., & Nedergaard, M. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2014.08.010 · Cited by 218 · see citing works

P2Y1 Receptor-evoked Glutamate Exocytosis from Astrocytes

Domercq, M., Brambilla, L., Pilati, E., Marchaland, J., Volterra, A., & Bezzi, P. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m606429200 · Cited by 215 · see citing works

Synaptotagmin IV regulates glial glutamate release

Zhang, Q., Fukuda, M., Bockstaele, E. V., Pascual, O., & Haydon, P. G. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0401960101 · Cited by 208 · see citing works

CYTOLOGY AND CELLULAR PATHOLOGY OF THE NERVOUS SYSTEM

Penfield, W. G. (1933) · The American Journal of the Medical Sciences · doi:10.1097/00000441-193301000-00013 · Cited by 205 · see citing works

Natriuretic peptide C receptor signalling in the heart and vasculature

Rose, R. A., & Giles, W. R. (2007) · The Journal of Physiology · doi:10.1113/jphysiol.2007.144253 · Cited by 204 · see citing works

Regulated trafficking of neurotransmitter transporters: common notes but different melodies

Robinson, M. B. (2001) · Journal of Neurochemistry · doi:10.1046/j.0022-3042.2001.00698.x · Cited by 204 · see citing works

Exosome-mediated shuttling of microRNA-29 regulates HIV Tat and morphine-mediated Neuronal dysfunction

Hu, G., Yao, H., Chaudhuri, A. D., Duan, M., Yelamanchili, S. V., Wen, H., Cheney, P. D., Fox, H. S., & Buch, S. J. (2012) · Cell Death and Disease · doi:10.1038/cddis.2012.114 · Cited by 204 · see citing works

Gq-DREADD Selectively Initiates Glial Glutamate Release and Inhibits Cue-induced Cocaine Seeking

Scofield, M. D., Boger, H. A., Smith, R. J., Li, H., Haydon, P. G., & Kalivas, P. W. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.02.016 · Cited by 197 · see citing works

A Highly Ca2+-Sensitive Pool of Vesicles Contributes to Linearity at the Rod Photoreceptor Ribbon Synapse

Thoreson, W. B., Rábl, K., Townes‐Anderson, E., & Heidelberger, R. (2004) · Neuron · doi:10.1016/s0896-6273(04)00254-5 · Cited by 190 · see citing works

Channel-Mediated Lactate Release by K + -Stimulated Astrocytes

Sotelo-Hitschfeld, T., Niemeyer, M. I., Mächler, P., Ruminot, I., Lerchundi, R., Wyss, M. T., Stobart, J. L., Fernández‐Moncada, I., Valdebenito, R., Garrido-Gerter, P., et al. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.5036-14.2015 · Cited by 188 · see citing works

Expression of synaptobrevin II, cellubrevin and syntaxin but not SNAP‐25 in cultured astrocytes

Parpura, V., Fang, Y., Basarsky, T. A., Jahn, R., & Haydon, P. G. (1995) · FEBS Letters · doi:10.1016/0014-5793(95)01401-2 · Cited by 186 · see citing works

The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes

Minich, T., Riemer, J., Schulz, J. B., Wielinga, P., Wijnholds, J., & Dringen, R. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03737.x · Cited by 185 · see citing works

Critical role of ABCA1 transporter in sphingosine 1-phosphate release from astrocytes

Sato, K., Malchinkhuu, E., Horiuchi, Y., Mogi, C., Tomura, H., Tosaka, M., Yoshimoto, Y., Kuwabara, A., & Okajima, F. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04958.x · Cited by 183 · see citing works

Neurotransmitter transporters expressed in glial cells as regulators of synapse function

Eulenburg, V., & Gomeza, J. (2010) · Brain Research Reviews · doi:10.1016/j.brainresrev.2010.01.003 · Cited by 182 · see citing works

Astrocyte physiopathology: At the crossroads of intercellular networking, inflammation and cell death

Rossi, D. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.04.003 · Cited by 178 · see citing works

Properties of Ca2+‐dependent exocytosis in cultured astrocytes

Kreft, M., Stenovec, M., Rupnik, M. S., Grilc, S., Kržan, M., Potokar, M., Pangršič, T., Haydon, P. G., & Zorec, R. (2004) · Glia · doi:10.1002/glia.20018 · Cited by 174 · see citing works

Hyperosmolar Mannitol Stimulates Expression of Aquaporins 4 and 9 through a p38 Mitogen-activated Protein Kinase-dependent Pathway in Rat Astrocytes

Arima, H., Yamamoto, N., Sobue, K., Umenishi, F., Tada, T., Katsuya, H., & Asai, K. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m304368200 · Cited by 173 · see citing works

Uptake and recycling of pro-BDNF for transmitter-induced secretion by cortical astrocytes

Bergami, M., Santi, S., Formaggio, E., Cagnoli, C. M., Verderio, C., Blum, R., Berninger, B., Matteoli, M., & Canossa, M. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200806137 · Cited by 173 · see citing works

Storage and Uptake of d-Serine into Astrocytic Synaptic-Like Vesicles Specify Gliotransmission

Martineau, M., Shi, T., Puyal, J., Knolhoff, A. M., Dulong, J., Gasnier, B., Klingauf, J., Sweedler, J. V., Jahn, R., & Mothet, J. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3497-12.2013 · Cited by 172 · see citing works

Complement-Derived Anaphylatoxin C3a Regulates In Vitro Differentiation and Migration of Neural Progenitor Cells

Shinjyo, N., Ståhlberg, A., Dragunow, M., Pekny, M., & Pekna, M. (2009) · Stem Cells · doi:10.1002/stem.225 · Cited by 171 · see citing works

Vesicular and Plasma Membrane Transporters for Neurotransmitters

Blakely, R. D., & Edwards, R. H. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005595 · Cited by 169 · see citing works

Monocyte Derived Microvesicles Deliver a Cell Death Message via Encapsulated Caspase-1

Sarkar, A., Mitra, S., Mehta, S., Raices, R. M., & Wewers, M. D. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007140 · Cited by 168 · see citing works

ATP signaling is deficient in cultured pannexin1‐null mouse astrocytes

Suadicani, S. O., Iglesias, R., Wang, J., Dahl, G., Spray, D. C., & Scemes, E. (2012) · Glia · doi:10.1002/glia.22338 · Cited by 162 · see citing works

Der feinere Bau des Nervensystems im Lichte neuester Forschungen

Lenhossék, M. (1893) · Cited by 161 · see citing works

Heterogeneous responses of aquaporin-4 in oedema formation in a replicated severe traumatic brain injury model in rats

Ke, C., Poon, W. S., Ng, H., Pang, J. C., & Chan, Y. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)01589-0 · Cited by 158 · see citing works

Cytosolic phospholipase A2 is induced in reactive glia following different forms of neurodegeneration

Stephenson, D. T., Rash, K. S., Smalstig, B., Roberts, E. F., Johnstone, E., Sharp, J., Panetta, J., Little, S. P., Kramer, R. M., & Clemens, J. A. (1999) · Glia · doi:10.1002/(sici)1098-1136(199908)27:2 · Cited by 152 · see citing works

Alterations in the expression of the AQP family in cultured rat astrocytes during hypoxia and reoxygenation

Yamamoto, N., Yoneda, K., Asai, K., Sobue, K., Tada, T., Fujita, Y., Katsuya, H., Fujita, M., Aihara, N., Mase, M., et al. (2001) · Molecular Brain Research · doi:10.1016/s0169-328x(01)00064-x · Cited by 152 · see citing works

Distinct Initial SNARE Configurations Underlying the Diversity of Exocytosis

Kasai, H., Takahashi, N., & Tokumaru, H. (2012) · Physiological Reviews · doi:10.1152/physrev.00007.2012 · Cited by 150 · see citing works

A Regulated Secretory Pathway in Cultured Hippocampal Astrocytes

Calegari, F., Coco, S., Taverna, E., BASSETTI, M., Verderio, C., Corradi, N., Matteoli, M., & Rosa, P. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.32.22539 · Cited by 149 · see citing works

Multiple roles of the vesicular‐SNARE TI‐VAMP in post‐Golgi and endosomal trafficking

Chaineau, M., Danglot, L., & Galli, T. (2009) · FEBS Letters · doi:10.1016/j.febslet.2009.10.026 · Cited by 149 · see citing works

Tubulation of Class II MHC Compartments Is Microtubule Dependent and Involves Multiple Endolysosomal Membrane Proteins in Primary Dendritic Cells

Vyas, J. M., Kim, Y., Artavanis‐Tsakonas, K., Love, J. C., van der Veen, A. G., & Ploegh, H. L. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.11.7199 · Cited by 146 · see citing works

Two forms of single-vesicle astrocyte exocytosis imaged with total internal reflection fluorescence microscopy

Bowser, D. N., & Khakh, B. S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607625104 · Cited by 146 · see citing works

The Astrocyte-Derived α7 Nicotinic Receptor Antagonist Kynurenic Acid Controls Extracellular Glutamate Levels in the Prefrontal Cortex

Wu, H., Pereira, E. F. R., Bruno, J. P., Pellicciari, R., Albuquerque, E. X., & Schwarcz, R. M. (2009) · Journal of Molecular Neuroscience · doi:10.1007/s12031-009-9235-2 · Cited by 146 · see citing works

Identification of a molecular target for glutamate regulation of astrocyte water permeability

Gunnarson, E., Zelenina, M., Axehult, G., Song, Y., Bondar, A. A., Krieger, P., Brismar, H., Zelenin, S. M., & Aperia, A. C. (2008) · Glia · doi:10.1002/glia.20627 · Cited by 145 · see citing works

Protein Kinase Activation Increases Insulin Secretion by Sensitizing the Secretory Machinery to Ca2+

Wan, Q., Dong, Y., Yang, H., Lou, X., Ding, J., & Xu, T. (2004) · The Journal of General Physiology · doi:10.1085/jgp.200409082 · Cited by 144 · see citing works

Lysosomes Are the Major Vesicular Compartment Undergoing Ca2+-Regulated Exocytosis from Cortical Astrocytes

Li, D., Ropert, N., Koulakoff, A., Giaume, C., & Oheim, M. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0744-08.2008 · Cited by 143 · see citing works

Proteomic Analysis of Astrocytic Secretion in the Mouse

Lafon‐Cazal, M., Adjali, O., Galéotti, N., Poncet, J., Jouin, P., Homburger, V., Bockaert, J., & Marin, P. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211980200 · Cited by 143 · see citing works

Norepinephrine inhibits gamma-interferon-induced major histocompatibility class II (Ia) antigen expression on cultured astrocytes via beta-2-adrenergic signal transduction mechanisms.

Frohman, E. M., Vayuvegula, B., Gupta, S., & van den Noort, S. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.4.1292 · Cited by 142 · see citing works

Neuronal Transgene Expression in Dominant-Negative SNARE Mice

Fujita, T., Chen, M. J., Li, B., Smith, N. A., Peng, W., Sun, W., Toner, M. J., Kress, B. T., Wang, L., Benraiss, A., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.2585-14.2014 · Cited by 141 · see citing works

Glutamate Uptake Triggers Transporter-Mediated GABA Release from Astrocytes

Héja, L., Barabás, P., Nyitrai, G., Kékesi, K. A., Lasztóczi, B., Tőke, O., Tárkányi, G., Madsen, K. K., Schousboe, A., Dobolyi, Á., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007153 · Cited by 137 · see citing works

Astrocytes shed extracellular vesicles that contain fibroblast growth factor-2 and vascular endothelial growth factor

Proia, P., Schiera, G., Mineo, M., Ingrassia, A. M. R., Santoro, G., Savettieri, G., & Liegro, I. D. (2008) · International Journal of Molecular Medicine · doi:10.3892/ijmm.21.1.63 · Cited by 133 · see citing works

Synaptobrevin2‐expressing vesicles in rat astrocytes: insights into molecular characterization, dynamics and exocytosis

Crippa, D., Schenk, U., Francolini, M., Rosa, P., Verderio, C., Zonta, M., Pozzan, T., Matteoli, M., & Carmignoto, G. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.094052 · Cited by 131 · see citing works

Release of ATP from cultured rat astrocytes elicited by glutamate receptor activation

Queiróz, G., Gebicke‐Haerter, P. J., Schobert, A., Starke, K., & von Kügelgen, I. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00637-9 · Cited by 131 · see citing works

“Kiss-and-Run” Glutamate Secretion in Cultured and Freshly Isolated Rat Hippocampal Astrocytes

Chen, X., Wang, L., Zhou, Y., Zheng, L., & Zhou, Z. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.1640-05.2005 · Cited by 130 · see citing works

Differential vesicular distribution and trafficking of MMP‐2, MMP‐9, and their inhibitors in astrocytes

Sbai, O., Ould‐Yahoui, A., Ferhat, L., Gueye, Y., Bernard, A., Charrat, E., Mehanna, A., Risso, J., Chauvin, J., Fenouillet, E., et al. (2009) · Glia · doi:10.1002/glia.20927 · Cited by 129 · see citing works

Gap junction hemichannel-mediated release of glutathione from cultured rat astrocytes

Rana, S., & Dringen, R. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.12.043 · Cited by 127 · see citing works

Neuroglia Morphology and Function

(1955) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1955.tb49169.x · Cited by 126 · see citing works

Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder

Malta, C. D., Fryer, J. D., Settembre, C., & Ballabio, A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1209577109 · Cited by 123 · see citing works

Immunogold Detection of L-glutamate and D-serine in Small Synaptic-Like Microvesicles in Adult Hippocampal Astrocytes

Bergersen, L. H., Morland, C., Ormel, L., Rinholm, J. E., Larsson, M., Wold, J. F. H., Røe, Å. T., Stranna, A., Santello, M., Bouvier, D. S., et al. (2011) · Cerebral Cortex · doi:10.1093/cercor/bhr254 · Cited by 122 · see citing works

Astrocytes as eicosanoid‐producing cells

Murphy, S. P., Pearce, B., Jeremy, J., & Dandona, P. (1988) · Glia · doi:10.1002/glia.440010402 · Cited by 121 · see citing works

What do we know about gliotransmitter release from astrocytes?

Sahlender, D. A., Savtchouk, I., & Volterra, A. (2014) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2013.0592 · Cited by 119 · see citing works

Calcium-Dependent Exocytosis of Atrial Natriuretic Peptide from Astrocytes

Kržan, M., Stenovec, M., Kreft, M., Pangršič, T., Grilc, S., Haydon, P. G., & Zorec, R. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-05-01580.2003 · Cited by 117 · see citing works

IFN-γ-induced increase in the mobility of MHC class II compartments in astrocytes depends on intermediate filaments

Vardjan, N., Gabrijel, M., Potokar, M., Švajger, U., Kreft, M., Jeras, M., de Pablo, Y., Faiz, M., Pekny, M., & Zorec, R. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-144 · Cited by 117 · see citing works

Glial plasmalemmal vesicles: A subcellular fraction from rat hippocampal homogenate distinct from synaptosomes

Nakamura, Y., Iga, K., Shibata, T., Shudo, M., & Kataoka, K. (1993) · Glia · doi:10.1002/glia.440090107 · Cited by 116 · see citing works

Astrocytes shed large membrane vesicles that contain mitochondria, lipid droplets and ATP

Falchi, A. M., Sogos, V., Saba, F., Piras, M., Congiu, T., & Piludu, M. (2012) · Histochemistry and Cell Biology · doi:10.1007/s00418-012-1045-x · Cited by 115 · see citing works

A vasoactive peptide, endothelin-3, is produced by and specifically binds to primary astrocytes

Ehrenreich, H., Kerhl, J. H., Anderson, R. W., Rieckmann, P., Vitković, L., Coligan, J. E., & Fauci, A. S. (1991) · Brain Research · doi:10.1016/0006-8993(91)90375-6 · Cited by 115 · see citing works

The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation

Vascotto, F., Lankar, D., Faure-André, G., Vargas, P., Diaz, J., Roux, D. L., Yuseff, M.-I., Sibarita, J., Boes, M. L., Raposo, G., et al. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200611147 · Cited by 115 · see citing works

Mechanisms of GABA release from human astrocytes

Lee, M., McGeer, E. G., & McGeer, P. L. (2011) · Glia · doi:10.1002/glia.21202 · Cited by 113 · see citing works

Prostaglandin E2 production in astrocytes: regulation by cytokines, extracellular ATP, and oxidative agents

Xu, J., Chalimoniuk, M., Shu, Y., Simonyi, Á., Sun, A. Y., Gonzalez, F. A., Weisman, G. A., Wood, W. G., & Sun, G. Y. (2003) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/j.plefa.2003.08.016 · Cited by 113 · see citing works

Fast Subplasma Membrane Ca2+Transients Control Exo-Endocytosis of Synaptic-Like Microvesicles in Astrocytes

Marchaland, J., Calì, C., Voglmaier, S. M., Li, H., Regazzi, R., Edwards, R. H., & Bezzi, P. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0040-08.2008 · Cited by 113 · see citing works

TI‐VAMP/VAMP7 is the SNARE of secretory lysosomes contributing to ATP secretion from astrocytes

Verderio, C., Cagnoli, C. M., Bergami, M., Francolini, M., Schenk, U., Colombo, A. V., Riganti, L., Frassoni, C., Zuccaro, E., Danglot, L., et al. (2011) · Biology of the Cell · doi:10.1111/boc.201100070 · Cited by 112 · see citing works

Astrocytes Express Elements of the Class II Endocytic Pathway and Process Central Nervous System Autoantigen for Presentation to Encephalitogenic T Cells

Soos, J. M., Morrow, J., Ashley, T. A., Szente, B. E., Bikoff, E. K., & Zamvil, S. S. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.161.11.5959 · Cited by 111 · see citing works

Trafficking and Fusion of Neuropeptide Y-Containing Dense-Core Granules in Astrocytes

Ramamoorthy, P., & Whim, M. D. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5361-07.2008 · Cited by 110 · see citing works

Mitogenic effect of neuropeptide Y in rat vascular smooth muscle cells

Żukowska-Grójec, Z., Pruszczyk, P., Colton, C. A., Yao, J., Shen, G. H., Myers, A. K., & Wahlestedt, C. (1993) · Peptides · doi:10.1016/0196-9781(93)90040-n · Cited by 110 · see citing works

Confocal imaging and tracking of the exocytotic routes for D ‐serine‐mediated gliotransmission

Martineau, M., Galli, T., Baux, G., & Mothet, J. (2008) · Glia · doi:10.1002/glia.20696 · Cited by 109 · see citing works

Noradrenergic stimulation of BDNF synthesis in astrocytes: Mediation via α1- and β1/β2-adrenergic receptors

Jurič, D. M., Lončar, D., & Čarman‐Kržan, M. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.06.035 · Cited by 108 · see citing works

Cell-type specific mechanisms of D-serine uptake and release in the brain

Martineau, M., Parpura, V., & Mothet, J. (2014) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2014.00012 · Cited by 108 · see citing works

Central oxytocin and ANP receptors mediate osmotic inhibition of salt appetite in rats

Blackburn, R. E., Samson, W. K., Fulton, R. J., Stricker, E. M., & Verbalis, J. G. (1995) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1995.269.2.r245 · Cited by 107 · see citing works

Thyroid Hormone Action: Astrocyte–Neuron Communication

Morte, B., & Bernal, J. (2014) · Frontiers in Endocrinology · doi:10.3389/fendo.2014.00082 · Cited by 105 · see citing works

Two Ca2+-Dependent Steps Controlling Synaptic Vesicle Fusion and Replenishment at the Cerebellar Basket Cell Terminal

Sakaba, T. (2008) · Neuron · doi:10.1016/j.neuron.2007.11.029 · Cited by 102 · see citing works

Intermediate filaments attenuate stimulation‐dependent mobility of endosomes/lysosomes in astrocytes

Potokar, M., Stenovec, M., Gabrijel, M., Li, L., Kreft, M., Grilc, S., Pekny, M., & Zorec, R. (2010) · Glia · doi:10.1002/glia.21000 · Cited by 101 · see citing works

Prostaglandins are powerful inducers of NGF and BDNF production in mouse astrocyte cultures

Toyomoto, M., Ohta, M., Okumura, K., Yano, H., Matsumoto, K., Inoue, S., Hayashi, K., & Ikeda, K. (2004) · FEBS Letters · doi:10.1016/s0014-5793(04)00246-7 · Cited by 98 · see citing works

Glia re‐sealed particles freshly prepared from adult rat brain are competent for exocytotic release of glutamate

Stigliani, S., Zappettini, S., Raiteri, L., Passalacqua, M., Melloni, E., Venturi, C. B., Tacchetti, C., Diaspro, A., Usai, C., & Bonanno, G. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03631.x · Cited by 98 · see citing works

Calcium Triggers Exocytosis from Two Types of Organelles in a Single Astrocyte

Liu, T., Sun, L., Xiong, Y., Shang, S., Guo, N., Teng, S., Wang, Y., Liu, B., Wang, C., Wang, L., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6401-10.2011 · Cited by 96 · see citing works

Resolving vesicle fusion from lysis to monitor calcium-triggered lysosomal exocytosis in astrocytes

Jaiswal, J. K., Fix, M., Takano, T., Nedergaard, M., & Simon, S. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0704935104 · Cited by 94 · see citing works

Localization of SNARE proteins and secretory organelle proteins in astrocytes in vitro and in situ

Wilhelm, A., Volknandt, W., Langer, D. J., Nolte, C., Kettenmann, H., & Zimmermann, H. (2003) · Neuroscience Research · doi:10.1016/j.neures.2003.11.002 · Cited by 94 · see citing works

Rapid regulated dense-core vesicle exocytosis requires the CAPS protein

Rupnik, M. S., Kreft, M., Sikdar, S. K., Grilc, S., Romih, R., Zupanc̆ic̆, G., Martin, T. F. J., & Zorec, R. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.090359097 · Cited by 93 · see citing works

Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments

Wubbolts, R., Fernandez‐Borja, M., Jordens, I., Reits, E. A., Dusseljee, S., Echeverri, C. J., Vallee, R. B., & Neefjes, J. (1999) · Journal of Cell Science · doi:10.1242/jcs.112.6.785 · Cited by 93 · see citing works

Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: Implications for schizophrenia

Pershing, M. L., Bortz, D. M., Pocivavsek, A., Fredericks, P. J., Jørgensen, C. V., Vunck, S. A., Leuner, B., Schwarcz, R. M., & Bruno, J. P. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.10.017 · Cited by 90 · see citing works

Looks Can Be Deceiving: Reconsidering the Evidence for Gliotransmission

Sloan, S. A., & Barres, B. A. (2014) · Neuron · doi:10.1016/j.neuron.2014.12.003 · Cited by 89 · see citing works

Cell locations for AQP1, AQP4 and 9 in the non-human primate brain

Arciénega, I. I., Brunet, J. F., Bloch, J., & Badaut, J. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.02.059 · Cited by 88 · see citing works

Lack of Evidence for Vesicular Glutamate Transporter Expression in Mouse Astrocytes

Li, D., Hérault, K., Silm, K., Evrard, A., Wojcik, S. M., Oheim, M., Herzog, É., & Ropert, N. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3667-12.2013 · Cited by 86 · see citing works

Morphological evidence for vesicular glutamate release from astrocytes

Bergersen, L. H., & Gundersen, V. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.03.074 · Cited by 84 · see citing works

Vesicle mobility studied in cultured astrocytes

Potokar, M., Kreft, M., Pangršič, T., & Zorec, R. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.02.030 · Cited by 83 · see citing works

Relevance of Exocytotic Glutamate Release from Retinal Glia

Ślęzak, M., Grosche, A., Niemiec, A., Tanimoto, N., Pannicke, T., Münch, T. A., Crocker, B., Isope, P., Härtig, W., Beck, S. C., et al. (2012) · Neuron · doi:10.1016/j.neuron.2012.03.027 · Cited by 81 · see citing works

Differential mRNA expression patterns of the synaptotagmin gene family in the rodent brain

Mittelsteadt, T., Seifert, G., Álvarez‐Barón, E., Steinhäuser, C., Becker, A. J., & Schoch, S. (2008) · The Journal of Comparative Neurology · doi:10.1002/cne.21908 · Cited by 81 · see citing works

There's more to life than neurotransmission: the regulation of exocytosis by synaptotagmin VII

Andrews, N. W., & Chakrabarti, S. (2005) · Trends in Cell Biology · doi:10.1016/j.tcb.2005.09.001 · Cited by 79 · see citing works

Reduced d-serine levels in the nucleus accumbens of cocaine-treated rats hinder the induction of NMDA receptor-dependent synaptic plasticity

Curcio, L., Podda, M. V., Leone, L., Piacentini, R., Mastrodonato, A., Cappelletti, P., Sacchi, S., Pollegioni, L., Grassi, C., & D’Ascenzo, M. (2013) · Brain · doi:10.1093/brain/awt036 · Cited by 79 · see citing works

Sub‐micromolar increase in [Ca2+]i triggers delayed exocytosis of ATP in cultured astrocytes

Pryazhnikov, E., & Khiroug, L. S. (2007) · Glia · doi:10.1002/glia.20590 · Cited by 77 · see citing works

Astrocyte‐derived adenosine modulates increased sleep pressure during inflammatory response

Nadjar, A., Blutstein, T., Aubert, A., Layé, S., & Haydon, P. G. (2013) · Glia · doi:10.1002/glia.22465 · Cited by 76 · see citing works

Oxidant-mediated AA release from astrocytes involves cPLA(2) and iPLA(2).

Xu, J.-F., Yu, S., Sun, A. Y., & Sun, G. Y. (2003) · Free Radical Biology & Medicine · doi:10.1016/s0891-5849(03)00152-7 · Cited by 74 · see citing works

REST/NRSF governs the expression of dense-core vesicle gliosecretion in astrocytes

Prada, I., Marchaland, J., Podini, P., Magrassi, L., D’Alessandro, R., Bezzi, P., & Meldolesi, J. (2011) · The Journal of Cell Biology · doi:10.1083/jcb.201010126 · Cited by 74 · see citing works

Internalization and Proteolytic Action of Botulinum Toxins in CNS Neurons and Astrocytes

Verderio, C., Coco, S., Rossetto, O., Montecucco, C., & Matteoli, M. (1999) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1999.0730372.x · Cited by 72 · see citing works

Glutamate-triggered calcium signalling in mouse Bergmann glial cells in situ: role of inositol-1,4,5-trisphosphate-mediated intracellular calcium release

Kirischuk, S., Kirchhoff, F., Matyash, V., Kettenmann, H., & Verkhratsky, A. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00067-6 · Cited by 71 · see citing works

Excitable Astrocytes: Ca2+- and cAMP-Regulated Exocytosis

Vardjan, N., & Zorec, R. (2015) · Neurochemical Research · doi:10.1007/s11064-015-1545-x · Cited by 70 · see citing works

Making sense of Wnt signaling—linking hair cell regeneration to development

Jansson, L., Kim, G. S., & Cheng, A. G.-L. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00066 · Cited by 70 · see citing works

Ca2+-dependent mobility of vesicles capturing anti-VGLUT1 antibodies

Stenovec, M., Kreft, M., Grilc, S., Potokar, M., Kreft, M. E., Pangršič, T., & Zorec, R. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.08.020 · Cited by 70 · see citing works

Regulation of AQP4 surface expression via vesicle mobility in astrocytes

Potokar, M., Stenovec, M., Jorgačevski, J., Holen, T., Kreft, M., Ottersen, O. P., & Zorec, R. (2013) · Glia · doi:10.1002/glia.22485 · Cited by 68 · see citing works

Temporal characteristics of vesicular fusion in astrocytes: examination of synaptobrevin 2‐laden vesicles at single vesicle resolution

Malarkey, E. B., & Parpura, V. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.210435 · Cited by 67 · see citing works

SDF 1-alpha (CXCL12) triggers glutamate exocytosis from astrocytes on a millisecond time scale: Imaging analysis at the single-vesicle level with TIRF microscopy

Calì, C., Marchaland, J., Regazzi, R., & Bezzi, P. (2008) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2008.04.015 · Cited by 67 · see citing works

Intracellular Na+ concentration influences short‐term plasticity of glutamate transporter‐mediated currents in neocortical astrocytes

Unichenko, P., Myakhar, O., & Kirischuk, S. (2012) · Glia · doi:10.1002/glia.22294 · Cited by 64 · see citing works

Vesicular nucleotide transporter is involved in ATP storage of secretory lysosomes in astrocytes

Oya, M., Kitaguchi, T., Yanagihara, Y., Numano, R., Kakeyama, M., Ikematsu, K., & Tsuboi, T. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.07.043 · Cited by 64 · see citing works

SNARE protein expression in synaptic terminals and astrocytes in the adult hippocampus: A comparative analysis

Schubert, V., Bouvier, D. S., & Volterra, A. (2011) · Glia · doi:10.1002/glia.21190 · Cited by 63 · see citing works

Physiology of Astroglia

Verkhratsky, A., & Nedergaard, M. (2018) · Physiological Reviews · doi:10.1152/physrev.00042.2016 · Cited by 1,678 · see citing works

SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions

Sun, W., Cornwell, A., Li, J., Peng, S., Osorio, M. J., Aalling, N., Wang, S., Benraiss, A., Lou, N., Goldman, S. A., et al. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.3199-16.2017 · Cited by 357 · see citing works

Gliotransmission: Beyond Black-and-White

Savtchouk, I., & Volterra, A. (2018) · The Journal of Neuroscience · doi:10.1523/jneurosci.0017-17.2017 · Cited by 325 · see citing works

Astrocyte-derived extracellular vesicles: Neuroreparative properties and role in the pathogenesis of neurodegenerative disorders

Upadhya, R., Zingg, W., Shetty, S., & Shetty, A. K. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.04.017 · Cited by 282 · see citing works

LRRK2 mediates tubulation and vesicle sorting from lysosomes

Bonet-Ponce, L., Beilina, A., Williamson, C. D., Lindberg, E., Kluss, J. H., Saez-Atienzar, S., Landeck, N., Kumaran, R., Mamais, A., Bleck, C., et al. (2020) · Science Advances · doi:10.1126/sciadv.abb2454 · Cited by 230 · see citing works

Stratification of astrocytes in healthy and diseased brain

Verkhratsky, A., Zorec, R., & Parpura, V. (2017) · Brain Pathology · doi:10.1111/bpa.12537 · Cited by 236 · see citing works

Astroglial Glutamate Signaling and Uptake in the Hippocampus

Rose, C. R., Felix, L., Zeug, A., Dietrich, D., Reiner, A., & Henneberger, C. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00451 · Cited by 231 · see citing works

Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates

Rostami, J., Mothes, T., Kolahdouzan, M., Eriksson, O., Moslem, M., Bergström, J., Ingelsson, M., O’Callaghan, P., Healy, L. M., Falk, A., et al. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02158-3 · Cited by 224 · see citing works

Astrocyte Activation in Neurovascular Damage and Repair Following Ischaemic Stroke

Patabendige, A., Singh, A., Jenkins, S. I., Sen, J., & Chen, R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22084280 · Cited by 216 · see citing works

Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation

Yshii, L., Pasciuto, E., Bielefeld, P., Mascali, L. G., Lemaître, P., Marino, M., Dooley, J., Kouser, L., Verschoren, S., Lagou, V., et al. (2022) · Nature Immunology · doi:10.1038/s41590-022-01208-z · Cited by 214 · see citing works

The effects of microglia‐ and astrocyte‐derived factors on neurogenesis in health and disease

Araki, T., Ikegaya, Y., & Koyama, R. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.14969 · Cited by 208 · see citing works

Mitochondrial metabolism in astrocytes regulates brain bioenergetics, neurotransmission and redox balance

Rose, J., Brian, C., Pappa, A., Panayiotidis, M. I., & Franco, R. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.536682 · Cited by 196 · see citing works

Mitochondrial Dysfunction, Protein Misfolding and Neuroinflammation in Parkinson’s Disease: Roads to Biomarker Discovery

Picca, A., Guerra, F., Calvani, R., Romano, R., Coelho-Júnior, H. J., Bucci, C., & Marzetti, E. (2021) · Biomolecules · doi:10.3390/biom11101508 · Cited by 189 · see citing works

The Fas/Fap-1/Cav-1 complex regulates IL-1RA secretion in mesenchymal stem cells to accelerate wound healing

Kou, X., Xu, X., Chen, C., Sanmillan, M. L., Cai, T., Zhou, Y., Giraudo, C. G., Le, A. D., & Shi, S. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aai8524 · Cited by 188 · see citing works

Neuronal P2X7 Receptors Revisited: Do They Really Exist?

Illes, P., Khan, T. M., & Rubini, P. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.3103-16.2017 · Cited by 179 · see citing works

Circadian control of BDNF-mediated Nrf2 activation in astrocytes protects dopaminergic neurons from ferroptosis

Ishii, T., Warabi, E., & Mann, G. E. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.09.002 · Cited by 177 · see citing works

How is alpha‐synuclein cleared from the cell?

Stefanis, L., Emmanouilidou, E., Pantazopoulou, M., Kirik, D., Vekrellis, K., & Tofaris, G. K. (2019) · Journal of Neurochemistry · doi:10.1111/jnc.14704 · Cited by 174 · see citing works

Exosomes: Origins and Therapeutic Potential for Neurodegenerative Disease

Sarko, D. K., & McKinney, C. E. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00082 · Cited by 170 · see citing works

Ultrasound-mediated augmented exosome release from astrocytes alleviates amyloid-β-induced neurotoxicity

Deng, Z., Wang, J., Xiao, Y., Li, F., Niu, L., Liu, X., Meng, L., & Zheng, H. (2021) · Theranostics · doi:10.7150/thno.52436 · Cited by 171 · see citing works

Selective transport of neurotransmitters and modulators by distinct volume-regulated LRRC8 anion channels

Lutter, D., Ullrich, F., Lück, J. C., Kempa, S., & Jentsch, T. J. (2017) · Journal of Cell Science · doi:10.1242/jcs.196253 · Cited by 154 · see citing works

Neuronal P2X7 Receptor: Involvement in Neuronal Physiology and Pathology

Miras‐Portugal, M. T., Sebastián‐Serrano, Á., García, L. D. D., & Dı́az-Hernández, M. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3104-16.2017 · Cited by 154 · see citing works

Functional dissection of astrocyte-secreted proteins: Implications in brain health and diseases

Jha, M. K., Kim, J.-H., Song, G. J., Lee, W., Lee, I. K., Lee, H., An, S. S. A., Kim, S., & Suk, K. (2017) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2017.12.003 · Cited by 149 · see citing works

Astrocyte-derived exosomes suppress autophagy and ameliorate neuronal damage in experimental ischemic stroke

Pei, X., Li, Y., Zhu, L., & Zhou, Z.-L. (2019) · Experimental Cell Research · doi:10.1016/j.yexcr.2019.06.019 · Cited by 146 · see citing works

Persistent Malfunction of Glymphatic and Meningeal Lymphatic Drainage in a Mouse Model of Subarachnoid Hemorrhage

Pu, T., Zou, W., Feng, W., Zhang, Y., Wang, L., Wang, H., & Xiao, M. (2019) · Experimental Neurobiology · doi:10.5607/en.2019.28.1.104 · Cited by 143 · see citing works

Astrocytes in mouse models of tauopathies acquire early deficits and lose neurosupportive functions

Sidoryk‐Wȩgrzynowicz, M., Gerber, Y. N., Ries, M., Sastre, M., Tolkovsky, A. M., & Spillantini, M. G. (2017) · Acta Neuropathologica Communications · doi:10.1186/s40478-017-0478-9 · Cited by 137 · see citing works

Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments

Petrelli, F., Dallérac, G. M., Pucci, L., Calì, C., Zehnder, T., Sultan, S., Lecca, S., Chicca, A., Ivanov, A. D., Asensio, C. S., et al. (2018) · Molecular Psychiatry · doi:10.1038/s41380-018-0226-y · Cited by 127 · see citing works

Exosomes From Astrocyte Processes: Signaling to Neurons

Venturini, A., Passalacqua, M., Pelassa, S., Pastorino, F., Tedesco, M., Cortese, K., Gagliani, M. C., Leo, G., Maura, G., Guidolin, D., et al. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01452 · Cited by 128 · see citing works

6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment partially via suppressing astrocyte overactivation

Zhang, F., Zhang, J.-G., Yang, W., Xu, P., Xiao, Y., & Zhang, H. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.08.136 · Cited by 123 · see citing works

Extracellular Vesicles: Mechanisms in Human Health and Disease

Malloci, M., Perdomo, L., Veerasamy, M., Andriantsitohaina, R., Simard, G., & Martínez, M. C. (2018) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7265 · Cited by 122 · see citing works

Reactive Astrocytes in Brain Metastasis

Wasilewski, D., Priego, N., Torre, C. F., & Valiente, M. (2017) · Frontiers in Oncology · doi:10.3389/fonc.2017.00298 · Cited by 121 · see citing works

The homeostatic astroglia emerges from evolutionary specialization of neural cells

Verkhratsky, A., & Nedergaard, M. (2016) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2015.0428 · Cited by 133 · see citing works

Astroglia in Sepsis Associated Encephalopathy

Shulyatnikova, T. V., & Verkhratsky, A. (2019) · Neurochemical Research · doi:10.1007/s11064-019-02743-2 · Cited by 121 · see citing works

Amyloid-β oligomers in cellular models of Alzheimer’s disease

Fontana, I. C., Zimmer, A. R., Rocha, A. S., Gosmann, G., Souza, D. O., Lourenco, M. V., Ferreira, S. T., & Zimmer, E. R. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.15030 · Cited by 115 · see citing works

Extracellular vesicles and intercellular communication in the central nervous system

Lizarraga‐Valderrama, L. R., & Sheridan, G. K. (2021) · FEBS Letters · doi:10.1002/1873-3468.14074 · Cited by 107 · see citing works

Astrocytic Glutamatergic Transmission and Its Implications in Neurodegenerative Disorders

Satarker, S., Bojja, S. L., Gurram, P. C., Mudgal, J., Arora, D. S., & Nampoothiri, M. (2022) · Cells · doi:10.3390/cells11071139 · Cited by 112 · see citing works

Astrocytic signaling supports hippocampal–prefrontal theta synchronization and cognitive function

Sardinha, V. M., Guerra‐Gomes, S., Caetano, I., Tavares, G., Martins, M., Reis, J. S., Correia, J. S., Teixeira‐Castro, A., Pinto, L., Sousa, N., et al. (2017) · Glia · doi:10.1002/glia.23205 · Cited by 105 · see citing works

Astrocyte-Derived Exosomes Treated With a Semaphorin 3A Inhibitor Enhance Stroke Recovery via Prostaglandin D 2 Synthase

Hira, K., Ueno, Y., Tanaka, R., Miyamoto, N., Yamashiro, K., Inaba, T., Urabe, T., Okano, H., & Hattori, N. (2018) · Stroke · doi:10.1161/strokeaha.118.021272 · Cited by 110 · see citing works

Astroglia-specific contributions to the regulation of synapses, cognition and behaviour

Augusto‐Oliveira, M., Arrifano, G. D. P., Takeda, P. Y., Lopes-Araújo, A., Santos-Sacramento, L., Anthony, D. C., Verkhratsky, A., & Lopez, M. E. C. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.07.039 · Cited by 107 · see citing works

Astroglia-Derived ATP Modulates CNS Neuronal Circuits

Illés, P., Burnstock, G., & Tang, Y. (2019) · Trends in Neurosciences · doi:10.1016/j.tins.2019.09.006 · Cited by 104 · see citing works

Crosstalk between Neuron and Glial Cells in Oxidative Injury and Neuroprotection

Lee, K. H., Cha, M., & Lee, B. H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222413315 · Cited by 104 · see citing works

Astrocytes’ Contribution to Adult Neurogenesis in Physiology and Alzheimer’s Disease

Cassé, F., Richetin, K., & Toni, N. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00432 · Cited by 105 · see citing works

Dysregulation of Astrocyte–Neuronal Communication in Alzheimer’s Disease

Nanclares, C., Baraibar, A. M., Araque, A., & Kofuji, P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22157887 · Cited by 96 · see citing works

Astroglial Calcium Signaling in Aging and Alzheimer's Disease

Verkhratsky, A. (2019) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a035188 · Cited by 99 · see citing works

Unraveling the Link Between Mitochondrial Dynamics and Neuroinflammation

de Oliveira, L. G., Angelo, Y. D. S., Iglesias, A. H., & Peron, J. P. S. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.624919 · Cited by 98 · see citing works

Astroglia in Alzheimer’s Disease

Verkhratsky, A., Parpura, V., Rodríguez-Arellano, J., & Zorec, R. (2019) · Advances in Experimental Medicine and Biology · doi:10.1007/978-981-13-9913-8_11 · Cited by 47 · see citing works

Cathepsin B Gene Knockout Improves Behavioral Deficits and Reduces Pathology in Models of Neurologic Disorders

Hook, G., Reinheckel, T., Ni, J., Wu, Z., Kindy, M. S., Peters, C., & HOOK, V. Y. H. (2022) · Pharmacological Reviews · doi:10.1124/pharmrev.121.000527 · Cited by 95 · see citing works

Organ‐On‐A‐Chip Models of the Blood–Brain Barrier: Recent Advances and Future Prospects

Kawakita, S., Mandal, K., Mou, L., Mecwan, M. M., Zhu, Y., Li, S., Sharma, S., Hernández, A. L., Nguyen, H. T., Maity, S., et al. (2022) · Small · doi:10.1002/smll.202201401 · Cited by 94 · see citing works

Astrocyte-derived extracellular vesicles: A double-edged sword in central nervous system disorders

Zhao, S., Sheng, S., Wang, Y., Ding, L., Xu, X., Xia, X., & Zheng, J. C. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.027 · Cited by 90 · see citing works

Phagocytic astrocytes: Emerging from the shadows of microglia

Konishi, H., Koizumi, S., & Kiyama, H. (2022) · Glia · doi:10.1002/glia.24145 · Cited by 88 · see citing works

Astrocytes at the Hub of the Stress Response: Potential Modulation of Neurogenesis by miRNAs in Astrocyte-Derived Exosomes

Luarte, A., Cisternas, P., Caviedes, A., Bátiz, L. F., Lafourcade, C., Wyneken, Ú., & Henzi, R. (2017) · Stem Cells International · doi:10.1155/2017/1719050 · Cited by 87 · see citing works

Crosslink between calcium and sodium signalling

Verkhratsky, A., Trebak, M., Perocchi, F., Khananshvili, D., & Sekler, I. (2017) · Experimental Physiology · doi:10.1113/ep086534 · Cited by 87 · see citing works

Satellite Glial Cells and Astrocytes, a Comparative Review

Menachem Hanani, A., & Verkhratsky, A. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03255-8 · Cited by 86 · see citing works

Aberrant astrocyte protein secretion contributes to altered neuronal development in multiple models of neurodevelopmental disorders.

Caldwell, A. L. M., Sancho, L., Deng, J., Bosworth, A., Miglietta, A., Diedrich, J. K., Shokhirev, M. N., & Allen, N. J. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01150-1 · Cited by 86 · see citing works

Memristive Circuit Implementation of a Self-Repairing Network Based on Biological Astrocytes in Robot Application

Hong, Q., Chen, H., Sun, J., & Wang, C. (2020) · IEEE Transactions on Neural Networks and Learning Systems · doi:10.1109/tnnls.2020.3041624 · Cited by 85 · see citing works

Astrocyte dysfunction in Parkinson's disease: from the perspectives of transmitted α-synuclein and genetic modulation

Wang, C., Yang, T., Liang, M., Xie, J., & Song, N. (2021) · Translational Neurodegeneration · doi:10.1186/s40035-021-00265-y · Cited by 85 · see citing works

In vivo methods for imaging blood–brain barrier function and dysfunction

Harris, W. J., Asselin, M., Hinz, R., Parkes, L. M., Allan, S. M., Schießl, I., Boutin, H., & Dickie, B. (2022) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-022-05997-1 · Cited by 87 · see citing works

The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system

Bouyakdan, K., Martin, H., Liénard, F., Budry, L., Taïb, B., Rodaros, D., Chrétien, C., Biron, É., Husson, Z., Cota, D., et al. (2019) · Journal of Clinical Investigation · doi:10.1172/jci123454 · Cited by 82 · see citing works

Astrocyte-derived TNF and glutamate critically modulate microglia activation by methamphetamine

Canedo, T., Portugal, C. C., Socodato, R., Almeida, T. O., Terceiro, A. F., Bravo, J., Silva, A. I., Magalhães, J. D., Guerra‐Gomes, S., Oliveira, J. F., et al. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01139-7 · Cited by 80 · see citing works

Dengue Virus Infection of Blood–Brain Barrier Cells: Consequences of Severe Disease

Calderón-Peláez, M.-A., Velandia-Romero, M. L., Bastidas-Legarda, L. Y., Beltrán, E. O., Camacho-Ortega, S. J., & Castellanos, J. E. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01435 · Cited by 83 · see citing works

Astrocyte regulation of synaptic signaling in psychiatric disorders

Kruyer, A., Kalivas, P. W., & Scofield, M. D. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01338-w · Cited by 76 · see citing works

l ‐DOPA‐induced dyskinesia and neuroinflammation: do microglia and astrocytes play a role?

Carta, A. R., Mulas, G., Bortolanza, M., Duarte, T. T., Pillai, E., Fisone, G., Raisman‐Vozari, R., & Bel, E. A. D. (2016) · European Journal of Neuroscience · doi:10.1111/ejn.13482 · Cited by 76 · see citing works

Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes

Jones, J. R., Kong, L., Hanna, M. G., Hoffman, B., Krencik, R., Bradley, R. A., Hagemann, T. L., Choi, J., Doers, M. E., Dubovis, M., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.09.083 · Cited by 73 · see citing works

Rising Stars: Astrocytes as a Therapeutic Target for ALS Disease

Izrael, M., Slutsky, S. G., & Revel, M. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00824 · Cited by 73 · see citing works

Astrocytes and major depression: The purinergic avenue

Zhao, Y. F., Verkhratsky, A., Tang, Y. C., & Illés, P. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109252 · Cited by 73 · see citing works

Establishing Co-Culture Blood–Brain Barrier Models for Different Neurodegeneration Conditions to Understand Its Effect on BBB Integrity

Park, J. S., Choe, K., Khan, A., Jo, M. H., Park, H. Y., Kang, M. H., Park, T. J., & Kim, M. O. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065283 · Cited by 72 · see citing works

The Key Role of Astrocytes in Amyotrophic Lateral Sclerosis and Their Commitment to Glutamate Excitotoxicity

Provenzano, F., Torazza, C., Bonifacino, T., Bonanno, G., & Milanese, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242015430 · Cited by 74 · see citing works

Astrocyte-Derived Exosomal microRNA miR-200a-3p Prevents MPP+-Induced Apoptotic Cell Death Through Down-Regulation of MKK4

Shakespear, N., Ogura, M., Yamaki, J., & Homma, Y. (2020) · Neurochemical Research · doi:10.1007/s11064-020-02977-5 · Cited by 72 · see citing works

Astrocytes: The Housekeepers and Guardians of the CNS

Verkhratsky, A., Parpura, V., Li, B., & Scuderi, C. (2021) · Advances in neurobiology · doi:10.1007/978-3-030-77375-5_2 · Cited by 72 · see citing works

Memory Formation Shaped by Astroglia

Zorec, R., Horvat, A., Vardjan, N., & Verkhratsky, A. (2015) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2015.00056 · Cited by 70 · see citing works

Enteric glia regulate gut motility in health and disease

Grubišić, V., Verkhratsky, A., Zorec, R., & Parpura, V. (2017) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2017.03.011 · Cited by 71 · see citing works

Astrocytes control synaptic strength by two distinct v-SNARE-dependent release pathways

Schwarz, Y. N., Zhao, N., Kirchhoff, F., & Bruns, D. (2017) · Nature Neuroscience · doi:10.1038/nn.4647 · Cited by 71 · see citing works

Regenerative Medicine Therapies for Targeting Neuroinflammation After Stroke

Rajkovic, O., Potjewyd, G., & Pinteaux, E. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00734 · Cited by 69 · see citing works

Glutathione: An Old and Small Molecule with Great Functions and New Applications in the Brain and in Alzheimer's Disease

Haddad, M., Hervé, V., Ben Khedher, M. R., Rabanel, J.-M., & Ramassamy, C. (2021) · Antioxidants & Redox Signaling · doi:10.1089/ars.2020.8129 · Cited by 68 · see citing works

Lipidomic characterization of extracellular vesicles in human serum

Chen, S., Chaudhuri, A. D., Deme, P., Dickens, A. M., Dastgheyb, R. M., Bhargava, P., Bi, H., & Haughey, N. J. (2019) · Journal of Circulating Biomarkers · doi:10.1177/1849454419879848 · Cited by 69 · see citing works

Cell-to-Cell Communication in Learning and Memory: From Neuro- and Glio-Transmission to Information Exchange Mediated by Extracellular Vesicles

Schiera, G., Liegro, C. M. D., & Liegro, I. D. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms21010266 · Cited by 67 · see citing works

Neuroprotective potential of astroglia

Liu, B., Teschemacher, A. G., & Kasparov, S. (2017) · Journal of Neuroscience Research · doi:10.1002/jnr.24140 · Cited by 62 · see citing works

The signaling role for chloride in the bidirectional communication between neurons and astrocytes

Wilson, C. S., & Mongin, A. A. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.01.012 · Cited by 62 · see citing works

NMDA Receptors in Astrocytes

Verkhratsky, A., & Chvátal, A. (2019) · Neurochemical Research · doi:10.1007/s11064-019-02750-3 · Cited by 61 · see citing works

Role of Extracellular Vesicles in Amyotrophic Lateral Sclerosis

Ferrara, D., Pasetto, L., Bonetto, V., & Basso, M. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00574 · Cited by 61 · see citing works

Dominant negative SNARE peptides stabilize the fusion pore in a narrow, release-unproductive state

Guček, A., Jorgačevski, J., Singh, P., Geisler, C., Lisjak, M., Vardjan, N., Kreft, M., Egner, A., & Zorec, R. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2213-2 · Cited by 60 · see citing works

Modulation of Spike-Timing Dependent Plasticity: Towards the Inclusion of a Third Factor in Computational Models

Foncelle, A., Mendes, A., Jędrzejewska‐Szmek, J., Valtcheva, S., Berry, H., Blackwell, K. T., & Venance, L. (2018) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2018.00049 · Cited by 59 · see citing works

Butylated Hydroxyanisole Exerts Neurotoxic Effects by Promoting Cytosolic Calcium Accumulation and Endoplasmic Reticulum Stress in Astrocytes

Park, S., Lee, J., Lim, W., You, S., & Song, G. (2019) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.9b02899 · Cited by 58 · see citing works

Inseparable tandem: evolution chooses ATP and Ca 2+ to control life, death and cellular signalling

Plattner, H., & Verkhratsky, A. (2016) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2015.0419 · Cited by 58 · see citing works

Don't forget astrocytes when targeting Alzheimer's disease

Sadick, J. S., & Liddelow, S. A. (2019) · British Journal of Pharmacology · doi:10.1111/bph.14568 · Cited by 58 · see citing works

GnRH neurons recruit astrocytes in infancy to facilitate network integration and sexual maturation

Pellegrino, G., Martin, M. J., Allet, C., Lhomme, T., Geller, S., Franssen, D., Mansuy‐Aubert, V., Manfredi-Lozano, M., Coutteau‐Robles, A., Delli, V., et al. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00960-z · Cited by 57 · see citing works

TRAP-seq Profiling and RNAi-Based Genetic Screens Identify Conserved Glial Genes Required for Adult Drosophila Behavior

Ng, F., Sengupta, S., Huang, Y., Yu, A. M., You, S., Roberts, M. A., Iyer, L. K., Yang, Y., & Jackson, F. R. (2016) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2016.00146 · Cited by 56 · see citing works

Intercellular Communication in the Brain through Tunneling Nanotubes

Khattar, K. E., Safi, J., Rodriguez, A., & Vignais, M. (2022) · Cancers · doi:10.3390/cancers14051207 · Cited by 53 · see citing works

Extracellular Vesicles and the Stress System

Makrygianni, E. A., & Chrousos, G. P. (2022) · Neuroendocrinology · doi:10.1159/000527182 · Cited by 57 · see citing works

Exploring the Role of Astroglial Glutamate Release and Association With Synapses in Neuronal Function and Behavior

Scofield, M. D. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.10.029 · Cited by 52 · see citing works

Signal transduction in astrocytes: Localization and release of inorganic polyphosphate

Angelova, P. R., Iversen, K. Z., Teschemacher, A. G., Kasparov, S., Gourine, A. V., & Abramov, A. Y. (2018) · Glia · doi:10.1002/glia.23466 · Cited by 53 · see citing works

Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling

Yin, J., Spillman, E., Cheng, E. S., Short, J., Chen, Y., Lei, J., Gibbs, M., Rosenthal, J., Sheng, C., Chen, Y. X., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22751-7 · Cited by 53 · see citing works

Long noncoding RNA NKILA transferred by astrocyte-derived extracellular vesicles protects against neuronal injury by upregulating NLRX1 through binding to mir-195 in traumatic brain injury

He, B., Chen, W., Zeng, J., Tong, W., & Zheng, P. (2021) · Aging · doi:10.18632/aging.202618 · Cited by 52 · see citing works

Sleep Deprivation Induces Cognitive Impairment by Increasing Blood-Brain Barrier Permeability via CD44

Sun, J., Wu, J., Hua, F., Chen, Y., Zhan, F., & Xu, G. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.563916 · Cited by 52 · see citing works

CREB Regulates Distinct Adaptive Transcriptional Programs in Astrocytes and Neurons

Pardo, L., Valor, L. M., Eraso‐Pichot, A., Barco, Á., Golbano, A., Hardingham, G. E., Masgrau, R., & Galea, E. (2017) · Scientific Reports · doi:10.1038/s41598-017-06231-x · Cited by 50 · see citing works

Ca2+-Dependent and Ca2+-Independent ATP Release in Astrocytes

Xiong, Y., Sun, S., Teng, S., Jin, M., & Zhou, Z. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00224 · Cited by 49 · see citing works

Calcium and ATP control multiple vital functions

Petersen, O. H., & Verkhratsky, A. (2016) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2015.0418 · Cited by 48 · see citing works

Editing the Central Nervous System Through CRISPR/Cas9 Systems

Cota-Coronado, A., Díaz-Martínez, N. F., Padilla‐Camberos, E., & Diaz-Martinez, N. E. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00110 · Cited by 48 · see citing works

Short and long TNF‐alpha exposure recapitulates canonical astrogliosis events in human‐induced pluripotent stem cells‐derived astrocytes

Trindade, P., Loiola, E. C., Gasparotto, J., Ribeiro, C. T., Cardozo, P. L., Devalle, S., Salerno, J. A., Ornelas, I. M., Ledur, P. F., Ribeiro, F. M., et al. (2020) · Glia · doi:10.1002/glia.23786 · Cited by 46 · see citing works

Astrogliopathology in the infectious insults of the brain

Zorec, R., Avšič‐Županc, T., & Verkhratsky, A. (2018) · Neuroscience Letters · doi:10.1016/j.neulet.2018.08.003 · Cited by 45 · see citing works

Role of astrocyte purinergic signaling in epilepsy

Nikolic, L. M., Nobili, P., Shen, W., & Audinat, É. (2019) · Glia · doi:10.1002/glia.23747 · Cited by 49 · see citing works

Gliocrine System: Astroglia as Secretory Cells of the CNS

Vardjan, N., Parpura, V., Verkhratsky, A., & Zorec, R. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-9913-8_4 · Cited by 29 · see citing works

Secretory Astrocytes

Verkhratsky, A., & Zorec, R. (2020) · Masterclass in neuroendocrinology · doi:10.1007/978-3-030-22989-4_7

Physiopathologic dynamics\n\t\t\t\t of vesicle traffic in astrocytes

Potokar, M., Stenovec, M., Kreft, M., Gabrijel, M., & Zorec, R. (2011) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

Exocytosis in Astrocytes: Transmitter Release and Membrane Signal Regulation

Guček, A., Vardjan, N., & Zorec, R. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0773-6 · Cited by 60 · see citing works

Physiopathologic dynamics \nof vesicle traffic in astrocytes

Potokar, M., Stenovec, M., Kreft, M., Gabrijel, M., & Zorec, R. (2011) · Digitum: Institutional Repository of the University of Murcia (University of Murcia)