Cited by 327Telemedicine and Telehealth ImplementationHeart Failure Treatment and ManagementMobile Health and mHealth Applications

The DOI matches its Crossref record; 77 of the 79 references it cites were found in a registry or an index, and 2 are not checked yet; none of the 136 sources its claims cite is checked for support yet.

Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews

Open access

Kitsiou, Spyros, Paré, Guy, Jaana, Mirou·2015·Journal of Medical Internet Research

DOI 10.2196/jmir.4174PMC PMC4376138

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Abstract

BACKGROUND: Growing interest on the effects of home telemonitoring on patients with chronic heart failure (HF) has led to a rise in the number of systematic reviews addressing the same or very similar research questions with a concomitant increase in discordant findings. Differences in the scope, methods of analysis, and methodological quality of systematic reviews can cause great confusion and make it difficult for policy makers and clinicians to access and interpret the available evidence and for researchers to know where knowledge gaps in the extant literature exist. OBJECTIVE: This overview aims to collect, appraise, and synthesize existing evidence from multiple systematic reviews on the effectiveness of home telemonitoring interventions for patients with chronic heart failure (HF) to inform policy makers, practitioners, and researchers. METHODS: A comprehensive literature search was performed on MEDLINE, EMBASE, CINAHL, and the Cochrane Library to identify all relevant, peer-reviewed systematic reviews published between January 1996 and December 2013. Reviews were searched and screened using explicit keywords and inclusion criteria. Standardized forms were used to extract data and the methodological quality of included reviews was appraised using the AMSTAR (assessing methodological quality of systematic reviews) instrument. Summary of findings tables were constructed for all primary outcomes of interest, and quality of evidence was graded by outcome using the GRADE (Grades of Recommendation, Assessment, Development, and Evaluation) system. Post-hoc analysis and subgroup meta-analyses were conducted to gain further insights into the various types of home telemonitoring technologies included in the systematic reviews and the impact of these technologies on clinical outcomes. RESULTS: A total of 15 reviews published between 2003 and 2013 were selected for meta-level synthesis. Evidence from high-quality reviews with meta-analysis indicated that taken collectively, home telemonitoring interventions reduce the relative risk of all-cause mortality (0.60 to 0.85) and heart failure-related hospitalizations (0.64 to 0.86) compared with usual care. Absolute risk reductions ranged from 1.4%-6.5% and 3.7%-8.2%, respectively. Improvements in HF-related hospitalizations appeared to be more pronounced in patients with stable HF: hazard ratio (HR) 0.70 (95% credible interval [Crl] 0.34-1.5]). Risk reductions in mortality and all-cause hospitalizations appeared to be greater in patients who had been recently discharged (≤28 days) from an acute care setting after a recent HF exacerbation: HR 0.62 (95% CrI 0.42-0.89) and HR 0.67 (95% CrI 0.42-0.97), respectively. However, quality of evidence for these outcomes ranged from moderate to low suggesting that further research is very likely to have an important impact on our confidence in the observed estimates of effect and may change these estimates. The post-hoc analysis identified five main types of non-invasive telemonitoring technologies included in the systematic reviews: (1) video-consultation, with or without transmission of vital signs, (2) mobile telemonitoring, (3) automated device-based telemonitoring, (4) interactive voice response, and (5) Web-based telemonitoring. Of these, only automated device-based telemonitoring and mobile telemonitoring were effective in reducing the risk of all-cause mortality and HF-related hospitalizations. More research data are required for interactive voice response systems, video-consultation, and Web-based telemonitoring to provide robust conclusions about their effectiveness. CONCLUSIONS: Future research should focus on understanding the process by which home telemonitoring works in terms of improving outcomes, identify optimal strategies and the duration of follow-up for which it confers benefits, and further investigate whether there is differential effectiveness between chronic HF patient groups and types of home telemonitoring technologies.

Checked 2026-10-06 · 2 references not checked yet

AI snapshot

Written from the paper’s full text.

TL;DR

This overview of 15 systematic reviews found that home telemonitoring for chronic heart failure was associated with reduced all-cause mortality and HF-related hospitalizations versus usual care, but the quality of evidence was moderate to low. Post-hoc analyses suggested only automated device-based and mobile telemonitoring were effective, while other technologies lacked robust data.

Key findings

Across high-quality reviews with meta-analysis, home telemonitoring reduced the relative risk of all-cause mortality (0.60 to 0.85) and HF-related hospitalizations (0.64 to 0.86) compared with usual care; absolute risk reductions ranged from 1.4%-6.5% and 3.7%-8.2%, respectively.
The strongest evidence (moderate quality) came from a Cochrane review: all-cause mortality RR 0.66 (95% CI 0.54-0.81) in 2710 patients/11 RCTs, ARR 5.2%, number needed to treat 19; HF-related hospitalizations RR 0.79 (95% CI 0.67-0.94) in 1570 patients/4 RCTs, ARR 6%.
Recently discharged patients (≤28 days) showed greater reductions in mortality and all-cause hospitalizations: HR 0.62 (95% CrI 0.42-0.89) and HR 0.67 (95% CrI 0.42-0.97), respectively, but quality of evidence was low.
Post-hoc analyses found automated device-based telemonitoring reduced all-cause mortality (RR 0.65 [0.54-0.79]) and HF-related hospitalizations (RR 0.77 [0.64-0.91]); mobile telemonitoring showed beneficial but statistically inconclusive trends; interactive voice response and video-consultation were not associated with benefit.

Methods

Overview of systematic reviews: searched MEDLINE, EMBASE, CINAHL, and the Cochrane Library through December 2013, updated December 2014; included 15 peer-reviewed systematic reviews published 2003-2013 (18 references), covering 105 primary HT studies.
Data extraction, AMSTAR quality appraisal, GRADE evidence grading, summary-of-findings tables, citation overlap analysis, and a taxonomy classifying reviews by PICO characteristics.
Post-hoc subgroup meta-analyses of RCTs by home telemonitoring technology used risk ratios, intention-to-treat analysis, Mantel-Haenszel method, and random-effects models; some included reviews used Bayesian credible intervals.

Limitations

The paper states overviews are constrained by the quality and reporting of included reviews, publication lag, and overlap between reviews; only 3/15 reviews were high quality (AMSTAR ≥8), 4 were moderate, and 8 were low quality.
The paper states evidence quality was moderate to low due to risk of bias, imprecision, and heterogeneity; most trials lacked details on randomization, allocation concealment, and blinding, and one third of trials contributing data received commercial funding.
Evident from the text: the post-hoc technology analyses were exploratory, often based on few RCTs, and should be considered hypothesis-generating; the overview found no high-quality evidence for or against home telemonitoring effectiveness.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.2196/jmir.4174

Cites

77 of 79 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

0 of 136 cited sources checked · 0 supported · 0 flagged

A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“A total of 15 reviews published between 2003 and 2013 were selected for meta-level synthesis.”
- Also stated in: § Description of the Included Systematic Reviews · plain
  “After completion of the screening process, we identified 15 systematic reviews for inclusion (18 references; 3 systematic reviews had duplicate publications) [33-50].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Abstract > Results
Load-bearingStrength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes

Show all 122 claims

Probably not a substantial claim. 42
It may state two separate claims as one. 40
The quote only partly states this claim. 2

In the paper
“One review [37] focused primarily on HF patients who had been recently discharged (within 28 days) from an acute care setting after a recent HF exacerbation and conducted additional analyses to assess whether or not the results from these studies differed markedly from the results of studies that included patients with stable HF.”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Results > Population
What the sources say
- Not checked yetcites [37] source
Strength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passes
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“However, reporting of the active ingredients of these interventions was often poor in the included reviews and not consistently performed for all primary studies (eg, [36,38-40,46,47]).”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Results > Intervention
What the sources say
- Not checked yetcites [36] source
- Not checked yetcites [38] Louis, Amala A, 2003, Eur J Heart Fail source
- Not checked yetcites [39] source
- Not checked yetcites [40] source
- Not checked yetcites [46] source
- Not checked yetcites [47] source
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Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“The highest reported mean age in a study was 85 years [36] and the lowest was 48 years [39].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Results > Population
What the sources say
- Not checked yetcites [36] source
- Not checked yetcites [39] source
Strength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“Relative risk reductions in the four reviews that incorporated meta-analysis ranged from 14% (HR 0.86 [95% CI 0.61-1.21)] [37] to 36% (HR 0.64 [95% CrI 0.34-1.14]), while the ARR in HF-related hospitalizations extended from 3.7%-8.2%.”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Results > Home Telemonitoring Effects
What the sources say
- Not checked yetcites [37] source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“The remaining six summarized the available evidence narratively using various qualitative or semi-quantitative techniques [38,39,41,43,45].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Results > Home Telemonitoring Effects
What the sources say
- Not checked yetcites [38] Louis, Amala A, 2003, Eur J Heart Fail source
- Not checked yetcites [39] source
- Not checked yetcites [41] source
- Not checked yetcites [43] source
- Not checked yetcites [45] source
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Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“Of them, five pooled study results into a meta-analysis [33-37].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Results > Home Telemonitoring Effects
What the sources say
- Not checked yetcites [33] source
- Not checked yetcites [34] source
- Not checked yetcites [35] source
- Not checked yetcites [36] source
- Not checked yetcites [37] source
Strength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“Eight reviews concurred that the impact of HT interventions on health care costs appeared to be positive in more cases than not, but in general results were statistically inconclusive and varied depending on the context and specific national health system of the study [34,36,38,39,41,43,44,47].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Results > Home Telemonitoring Effects
What the sources say
- Not checked yetcites [34] source
- Not checked yetcites [36] source
- Not checked yetcites [38] Louis, Amala A, 2003, Eur J Heart Fail source
- Not checked yetcites [39] source
- Not checked yetcites [41] source
- Not checked yetcites [43] source
- Not checked yetcites [44] source
- Not checked yetcites [47] source
Load-bearingStrength:hedged· not yet calibratedCausal:conditional· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.
In the paper
“Evidence about cost-effectiveness remains limited, and there are no reliable data on the long-term benefits and economic implications of HT interventions [51].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Discussion > Summary of the Evidence
What the sources say
- Not checked yetcites [51] source
Strength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passes
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Quality of evidence in included systematic reviews was assessed by outcome using the Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) system criteria [17-27].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Methods > Quality of Evidence in Included Systematic Reviews
What the sources say
- Not checked yetcites [17] source
- Not checked yetcites [18] source
- Not checked yetcites [19] source
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- Not checked yetcites [26] source
Load-bearingStrength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
Probably not a substantial claim.
In the paper
“AMSTAR is a validated instrument that uses 11 items to assess the degree to which review methods are unbiased.”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Methods > Quality Assessment of Included Reviews
What the sources say
- Not checked yetcites [16] source
Strength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“In cases where reviews had not performed a risk of bias assessment, we performed this task independently using the six criteria of the Cochrane Collaboration tool [28].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Methods > Quality of Evidence in Included Systematic Reviews
What the sources say
- Not checked yetcites [28] Higgins, Julian PT, 2008, Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series source
Load-bearingStrength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
Probably not a substantial claim.
In the paper
“The methodological quality of the included systematic reviews was independently assessed by the first two authors using the Assessment of Multiple Systematic Reviews (AMSTAR) tool [16].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Methods > Quality Assessment of Included Reviews
What the sources say
- Not checked yetcites [16] source
Load-bearingStrength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
Probably not a substantial claim.
None of the sources cited for this claim have been checked yet.
In the paper
“As shown below, the Cochrane Collaboration methodology [11] and available methodological guidelines for overviews of reviews [12,13] were rigorously applied throughout this study.”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Methods > Overview
What the sources say
- Not checked yetcites [11] Becker, LA, 2008, Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series source
- Not checked yetcites [12] source
- Not checked yetcites [13] Whitlock, Evelyn P, 2008, Ann Intern Med source
Strength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“It can be particularly helpful for those living in remote and rural areas, the elderly and frail who are housebound, as well as those at high risk of deterioration [5].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Introduction
What the sources say
- Not checked yetcites [5] source
Strength:plain· not yet calibratedCausal:conditional· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passes
It may state two separate claims as one.
In the paper
“Overviews of systematic reviews are an efficient way to gather and summarize in a single source the best available evidence on the effectiveness of interventions.”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Introduction
What the sources say
- Not checked yetcites [10] source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✗ Checkable: fails✓ Load-bearing: passes✓ Based: passes
Probably not a substantial claim. It may be too vague to check against evidence.
In the paper
“A recent critical review indicated that among all chronic conditions, HF has attracted the highest number of primary studies and systematic reviews [7].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Introduction
What the sources say
- Not checked yetcites [7] source
Strength:hedged· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“As shown in Table 9, the strongest evidence (moderate quality) comes from a high-quality meta-analysis of 4 large RCTs (N=1570 patients), which found statistically significant risk reductions of 21% in HF-related hospitalizations with HT versus usual care, equating to an ARR of 6% (95% CI-1.7 to -9.7) [34].”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Results > Home Telemonitoring Effects
What the sources say
- Not checked yetcites [34] source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibratedn = 1,570
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.
In the paper
“While HT with 24/4 clinical support yielded beneficial but marginally lower relative effects than those observed in recently discharged patients: HR 0.84 (95% CrI 0.54-1.15); ARR 5.7% (-1.8 to 4.8%).”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Results > Home Telemonitoring Effects
What the sources say
- Not checked yetcites [37] source
Strength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passes
It may state two separate claims as one. The quote only partly states this claim.
In the paper
“In the pooling of all-cause mortality data from 11 RCTs involving 2710 patients with HF, HT resulted in statistically significant risk reduction of 34% (RR 0.66 [95% CI 0.54-0.81]); an ARR of 5.2% (95% CI -2.9 to -7.1), equating to a number needed to treat of 19 to postpone one death.”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Results > Home Telemonitoring Effects
What the sources say
- Not checked yetcites [34] source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibratedn = 2,710
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.
In the paper
“However, results were statistically inconclusive and the overall quality of evidence was found to be low, suggesting that these estimates should be interpreted with caution until more evidence accumulates.”
§ Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews > Results > Home Telemonitoring Effects
What the sources say
- Not checked yetcites [37] source
Load-bearingStrength:hedged· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.

69 of 69

The paper relies on this without support.
Systematic reviews of home telemonitoring for heart failure have produced discordant findings in terms of direction and magnitude of home telemonitoring effects.
“Growing interest on the effects of home telemonitoring on patients with HF has led to a rise in the number of reviews addressing the same or very similar research questions with a concurrent increase in discordant findings in terms of direction and magnitude of HT effects.”
The paper relies on this without support.
Differences in scope, methods of analysis, results, and quality of systematic reviews make it difficult for policy makers to access and interpret review-level evidence and for researchers to identify evidence gaps.
“Differences in scope, methods of analysis, results, and quality of systematic reviews can cause great confusion and make it difficult for policy makers to access the review-level evidence, and for researchers to know where gaps in the evidence exist.”
The paper relies on this without support.
Home telemonitoring enables early detection of clinical decompensation in patients with heart failure, allowing timely intervention to prevent mortality events or further deterioration necessitating hospitalization.
“By allowing clinical data to be remotely collected on a regular basis, HT can enable early detection of clinical decompensation in patients with HF, allowing for timely intervention to prevent mortality events or further deterioration of the patient’s condition necessitating hospitalization and use of more resources.”

3 of 3

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

Conclusion calls mobile telemonitoring effective despite inconclusive results
Major
The conclusion says mobile telemonitoring is effective at reducing mortality and HF-related hospitalizations, whereas the mobile-telemonitoring results explicitly say both outcomes were statistically inconclusive.
Conflicting counts of reviews reporting costs
Minor
The outcomes section says 12 reviews reported costs, while the cost-savings section says 11 examined that outcome.
Conflicting counts of reviews reporting length of stay
Minor
The outcomes section reports nine reviews for length of stay, but the dedicated section reports eight.
Louis review study-design counts do not total 24
Minor
The listed 6 RCTs and 12 observational studies total 18, not the stated 24 studies. The remaining six studies are not accounted for in this breakdown.
Reported 24 · recomputed 18
All-cause hospitalization confidence-limit percentage is tenfold too small
Minor
The table's lower confidence limit of 181 fewer per 1000 is 18.1% fewer, not the 1.8% given in the prose for the same 5.7% reduction.

5 of 5

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & The PRISMA Group (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000097 · Cited by 64,042 · cited 1×
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Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
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The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000100 · Cited by 28,164 · cited 1×
“…limitations, researchers are strongly encouraged to closely adhere to the available methodological and reporting guidelines for systematic reviews [70-72] and consider the AMSTAR evaluation criteria [16] in order to improve the methodological rigor and reporting quality of their work.”
Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series
(2008) · doi:10.1002/9780470712184 · Cited by 25,048 · cited 1×
“Finally, given our observation that 80% (12/15) of the systematic reviews assessed in this overview had moderate or major methodological limitations, researchers are strongly encouraged to closely adhere to the available methodological and reporting guidelines for systematic reviews [70-72] and consider the AMSTAR eva…”
The “Golden Age” of Probiotics: A Systematic Review and Meta-Analysis of Randomized and Observational Studies in Preterm Infants
Dermyshi, E., Wang, Y., Yan, C., Hong, W., Qiu, G., Gong, X., & Zhang, T. (2017) · Neonatology · doi:10.1159/000454668 · Cited by 24,586
Corrigendum to: 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC.
McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Böhm, M., Burri, H., Butler, J., Čelutkienė, J., Chioncel, O. D., et al. (2021) · PubMed · doi:10.1093/eurheartj/ehab670 · Cited by 20,604
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.005 · Cited by 19,575
The Effect of Riding as an Alternative Treatment for Children with Cerebral Palsy: A Systematic Review and Meta-Analysis
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Introduction to Meta‐Analysis
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Research works printed but not linked: 2

Jadad, A R, 1997, CMAJ, 156, 1411
ESC Press OfficeIndividualised treatment for heart failure is rarely available outside hospital - New telemonitoring systems could ‘radically’ change the situation200905302014-09-20http://www.escardio.org/about/press/press-releases/pr-09/Pages/Individualised-treatment-HF-hospital.aspxESC Press release Heart Failure Congress 2009http://www.escardio.org/about/press/press-releases/pr-09/Pages/Individualised-treatment-HF-hospital.aspx6WaYcS3L3

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Background
Effectiveness of Mobile Health Interventions on Diabetes and Obesity Treatment and Management: Systematic Review of Systematic Reviews
Wang, Y., Min, J., Khuri, J., Xue, H., Xie, B., A Kaminsky, L., & J Cheskin, L. (2020) · JMIR mHealth and uHealth · doi:10.2196/15400 · Cited by 250
“A thorough review of the evidence is needed and can help guide future research and interventions [38,39].”
Impact of Information and Communication Technologies on Nursing Care: Results of an Overview of Systematic Reviews
Rouleau, G., Gagnon, M.-P., Côté, J., Payne-Gagnon, J., Hudson, E., & Dubois, C.-A. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.6686 · Cited by 244
“For criteria 9, entailing the inappropriateness of methods used to combine findings, we answered “yes,” based on the decision rules developed by Kitsiou et al [45]: “reviews’authors made a statement regarding the inappropriateness of pooling data (eg, highlighted issues about heterogeneity or variability between the s…”
Culture as a cure
Bienassis, K. D., Kristensen, S., Burtscher, M., Brownwood, I., & Klazinga, N. S. (2020) · OECD health working papers · doi:10.1787/6ee1aeae-en · Cited by 244
Transparency in literature reviews: an assessment of reporting practices across review types and genres in top IS journals
Templier, M., & Paré, G. (2018) · European Journal of Information Systems · doi:10.1080/0960085x.2017.1398880 · Cited by 180
Self-citation
Medium-term effectiveness of a comprehensive internet-based and patient-specific telerehabilitation program with text messaging support for cardiac patients: randomized controlled trial
Frederix, I., Hansen, D., Coninx, K., Vandervoort, P., Vandijck, D., Hens, N., Van Craenenbroeck, E., Van Driessche, N., & Dendale, P. (2015) · Journal of Medical Internet Research · doi:10.2196/jmir.4799 · Cited by 185
“Recent literature findings confirmed telehealth interventions such as telemonitoring to be feasible and effective for heart failure patients [15-18].”
Connecting Systems, Data, and People: A Multidisciplinary Research Roadmap for Chronic Disease Management
Bardhan, I. R., Chen, H., & Karahanna, E. (2020) · MIS Quarterly · doi:10.25300/misq/2020/14644 · Cited by 192
“With the increasing presence of sensors, telemonitoring technologies have the potential to provide continuous feedback of a chronic patient’s condition either to the patient or to their healthcare providers (Kitsiou et al. 2015).”
Home-based versus centre-based cardiac rehabilitation
McDonagh, S. T. J., Dalal, H. M., Moore, S. F., Clark, C. E., Dean, S. G., Jolly, K. B., Cowie, A., Afzal, J., & Taylor, R. S. (2023) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007130.pub5 · Cited by 178
Understanding heart failure; explaining telehealth—a hermeneutic systematic review
Greenhalgh, T., A’Court, C., & Shaw, S. (2017) · BMC Cardiovascular Disorders · doi:10.1186/s12872-017-0594-2 · Cited by 141
“Meta-analyses of such trials, claim critics, have tended to take too little account of inter-study differences and give too much weight to flawed primary studies [6, 33, 38, 39, 64, 65].”
Background
Mobile health technology: a novel tool in chronic disease management
Fan, K., & Zhao, Y. (2021) · Intelligent Medicine · doi:10.1016/j.imed.2021.06.003 · Cited by 150
Digital physical therapy in the COVID-19 pandemic
Dantas, L. O., Barreto, R. P. G., & Ferreira, C. H. J. (2020) · Brazilian Journal of Physical Therapy · doi:10.1016/j.bjpt.2020.04.006 · Cited by 137
A Mobile Health Intervention Supporting Heart Failure Patients and Their Informal Caregivers: A Randomized Comparative Effectiveness Trial
Piette, J. D., Striplin, D., Marinec, N., Chen, J., Trivedi, R. B., Aron, D. C., Fisher, L., & Aikens, J. E. (2015) · Journal of Medical Internet Research · doi:10.2196/jmir.4550 · Cited by 131
“A number of recently completed clinical trials and evidence syntheses have shown that mobile health (mHealth) interventions can improve self-care behaviors and physiologic risk factors for poor outcomes of cardiovascular disease, including heart failure [12-16].”
Diffusion of the Digital Health Self-Tracking Movement in Canada: Results of a National Survey
Paré, G., Leaver, C. A., & Bourget, C. (2018) · Journal of Medical Internet Research · doi:10.2196/jmir.9388 · Cited by 113
“Although the use of connected care technologies could potentially benefit the growing population of patients with chronic conditions [29,30], the question remains as to whether it will diffuse broadly beyond early adopters and across cost inequities.”
BackgroundSelf-citation
Evaluating the Implementation of a Mobile Phone–Based Telemonitoring Program: Longitudinal Study Guided by the Consolidated Framework for Implementation Research
Ware, P., Ross, H. J., Cafazzo, J. A., Laporte, A., Gordon, K., & Seto, E. (2018) · JMIR mHealth and uHealth · doi:10.2196/10768 · Cited by 85
“Meta-analyses tend to support claims of the positive impact on heart failure outcomes [1,6-9]; however, important inconsistencies in the evidence persist [10].”
Background
A Remote Medication Monitoring System for Chronic Heart Failure Patients to Reduce Readmissions: A Two-Arm Randomized Pilot Study
Hale, T. M., Jethwani, K., Kandola, M. S., Saldaña, F., & Kvedar, J. C. (2016) · Journal of Medical Internet Research · doi:10.2196/jmir.5256 · Cited by 105
“A recent large scale RCT found no significant reduction in hospitalization and ED visits [16], whereas systematic reviews [15,17] and smaller studies have found positive effects [19,22-26].”
Outcomes of a Heart Failure Telemonitoring Program Implemented as the Standard of Care in an Outpatient Heart Function Clinic: Pretest-Posttest Pragmatic Study
Ware, P., Ross, H. J., Cafazzo, J. A., Boodoo, C., Munnery, M., & Seto, E. (2020) · Journal of Medical Internet Research · doi:10.2196/16538 · Cited by 102
“This is supported by several meta-analyses of randomized controlled trials (RCTs), which have concluded that TM reduces the risk of mortality and the number of hospitalizations when compared with the standard of care [10-13].”
BackgroundResultInfluential
A Mobile Health Intervention to Improve Self-Care in Patients With Heart Failure: Pilot Randomized Control Trial
Athilingam, P. R., Jenkins, B., Johansson, M., & Labrador, M. A. (2017) · JMIR Cardio · doi:10.2196/cardio.7848 · Cited by 95
“5), indicating appropriate selection of patients who are not in the refractory or end-stage HF [58].”
Background
Patient Adherence to a Mobile Phone–Based Heart Failure Telemonitoring Program: A Longitudinal Mixed-Methods Study
Ware, P., Dorai, M., Ross, H. J., Cafazzo, J. A., Laporte, A., Boodoo, C., & Seto, E. (2019) · JMIR mhealth and uhealth · doi:10.2196/13259 · Cited by 100
“According to several meta-analyses, these mechanisms work together to improve quality of life and reduce mortality and health care utilization compared with the standard of care without TM [2,7-10].”
Background
Two‐Year Mortality in Homebound Older Adults: An Analysis of the National Health and Aging Trends Study
Soones, T. N., Federman, A. D., Leff, B. A., Siu, A. L., & Ornstein, K. A. (2016) · Journal of the American Geriatrics Society · doi:10.1111/jgs.14467 · Cited by 102
“Similarly, home telehealth interventions have resulted in less healthcare use of homebound older adults with depression(39) and lower risks of hospitalization and death in individuals with congestive heart failure.(40,41) Given that telehealth interventions and HBPC can improve individual- and system-level outcomes by…”
Background
Cost‐Effectiveness of Remote Cardiac Monitoring With the CardioMEMS Heart Failure System
Schmier, J. K., Ong, K. L., & Fonarow, G. C. (2017) · Clinical Cardiology · doi:10.1002/clc.22696 · Cited by 98
“The effectiveness of remote monitoring may also depend on the particular monitoring device/system or patient characteristics.(15,16)”
Background
Nurse-Led Collaborative Management Using Telemonitoring Improves Quality of Life and Prevention of Rehospitalization in Patients with Heart Failure: A Pilot Study
Mizukawa, M., Moriyama, M., Yamamoto, H., Rahman, M. M., Naka, M., Kitagawa, T., Kobayashi, S., Oda, N., Yasunobu, Y., Tomiyama, M., et al. (2019) · International Heart Journal · doi:10.1536/ihj.19-313 · Cited by 87
mHealth education interventions in heart failure
Allida, S. M., Du, H., Xu, X., Prichard, R. A., Chang, S., Hickman, L., Davidson, P. M., & Inglis, S. C. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011845.pub2 · Cited by 90
Remote Monitoring of Patients With Heart Failure: A White Paper From the Heart Failure Society of America Scientific Statements Committee
Dickinson, M. G., Allen, L. A., Albert, N. M., DiSalvo, T. G., Ewald, G. A., Vest, A. R., Whellan, D. J., Zile, M. R., & Givertz, M. M. (2018) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2018.08.011 · Cited by 86
Effectiveness of Mobile Health Technology Interventions for Patients With Heart Failure: Systematic Review and Meta-analysis
Kitsiou, S., Vatani, H., Paré, G., Gerber, B. S., Buchholz, S. W., Kansal, M. M., Leigh, J. W., & Creber, R. M. (2021) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2021.02.015 · Cited by 83
Self-citation
Home Telemonitoring In Heart Failure: A Systematic Review And Meta-Analysis
Pekmezaris, R., Tortez, L. M., Williams, M. S., Patel, V. H., Makaryus, A. N., Zeltser, R., Sinvani, L., Wolf‐Klein, G. P., Lester, J., Sison, C. P., et al. (2018) · Health Affairs · doi:10.1377/hlthaff.2018.05087 · Cited by 93
Telehealth and Health Equity in Older Adults With Heart Failure: A Scientific Statement From the American Heart Association
Creber, R. M., Dodson, J. A., Bidwell, J. T., Breathett, K. K., Lyles, C. R., Still, C. H., Ooi, S., Yancy, C. W., & Kitsiou, S. (2023) · Circulation Cardiovascular Quality and Outcomes · doi:10.1161/hcq.0000000000000123 · Cited by 91
“28,38,50,64 One of the major weaknesses of using noninvasive remote monitoring for predicting or identifying episodes of worsening HF is the high rate of false-positive alerts that eventually leads to warnings being ignored due to mistrust.”
BackgroundInfluentialSelf-citation
Use of smartphone technology in cardiology
Nguyen, H. H., & Silva, J. N. A. (2015) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2015.11.002 · Cited by 79
“A recent meta-analysis of all the identified systematic reviews on the subject of the effectiveness of home telemonitoring interventions on patients with chronic heart failure from 2003 to 2103 showed that automated devicebased and mobile tele-monitoring of vital signs and symptoms are effective in reducing all-cause…”
Background
Features and usability assessment of a patient-centered mobile application (HeartMapp) for self-management of heart failure
Athilingam, P., Labrador, M. A., Remo, E. F. J., Mack, L., San Juan, A. B., & Elliott, A. F. (2016) · Applied Nursing Research · doi:10.1016/j.apnr.2016.07.001 · Cited by 78
The Effect of Telehealth on Hospital Services Use: Systematic Review and Meta-analysis
Peters, G. M., Kooij, L., Lenferink, A., van Harten, W. H., & Doggen, C. J. M. (2021) · Journal of Medical Internet Research · doi:10.2196/25195 · Cited by 78
“2% for patients with a condition-related hospitalization [6].”
BackgroundInfluential
Patient Use and Clinical Practice Patterns of Remote Cardiology Clinic Visits in the Era of COVID-19
Yuan, N., Pevnick, J. M., Botting, P. G., Elad, Y., Miller, S. J., Cheng, S. C., & Ebinger, J. E. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2021.4157 · Cited by 74
Using Telehealth to Reduce All-Cause 30-Day Hospital Readmissions among Heart Failure Patients Receiving Skilled Home Health Services
O’Connor, M. L., Dempsey, M., Huffenberger, A. M., Jost, S. G., Flynn, D., Norris, A. H., & Asdornwised, U. (2016) · Applied Clinical Informatics · doi:10.4338/aci-2015-11-soa-0157 · Cited by 73
Perceptions on use of home telemonitoring in patients with long term conditions – concordance with the Health Information Technology Acceptance Model: a qualitative collective case study
Middlemass, J., Vos, J., & Siriwardena, A. N. (2017) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-017-0486-5 · Cited by 69
“Health status, beliefs and concerns All patients had severe COPD and at least one other heart related condition which for some included confirmed heart failure.”
BackgroundInfluential
The effectiveness of remote monitoring of elderly patients after hospitalisation for heart failure: The renewing health European project
Olivari, Z., Giacomelli, S., Gubian, L., Mancin, S., Visentin, E., Francesco, V. D., Iliceto, S., Penzo, M., Zanocco, A., Marcon, C., et al. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.10.099 · Cited by 76
Evaluating the Use of Mobile Health Technology in Older Adults With Heart Failure: Mixed-Methods Study
Lefler, L. L., Rhoads, S., Harris, M., Funderburg, A. E., Lubin, S., Martel, I. D., Faulkner, J. L., Rooker, J. L., Bell, D. K., Marshall, H., et al. (2018) · JMIR Aging · doi:10.2196/12178 · Cited by 63
“Recently, mHealth was supported for reducing hospital readmissions [32,53,54] but not necessarily ED visits [51].”
Background
How does it work? Factors involved in telemedicine home-interventions effectiveness: A review of reviews
Bertoncello, C., Colucci, M., Baldovin, T., Buja, A., & Baldo, V. (2018) · PLoS ONE · doi:10.1371/journal.pone.0207332 · Cited by 68
The role of non-invasive devices for the telemonitoring of heart failure patients
Faragli, A., Abawi, D., Quinn, C., Cvetković, M., Schlabs, T., Tahirović, E., Düngen, H., Pieske, B. M., Kelle, S., Edelmann, F., et al. (2020) · Heart Failure Reviews · doi:10.1007/s10741-020-09963-7 · Cited by 66
“The most relevant criteria refer to symptomatic patients (NYHA class 3), with recent hospitalizations, a history of body fluids overload and a lack of appropriate medication adherence [106, 107].”
Background
The Use of Mobile Apps for Heart Failure Self-management: Systematic Review of Experimental and Qualitative Studies
Giordan, L. B., Tong, H. L., Atherton, J. J., Ronto, R., Chau, J. Y., Kaye, D. M., Shaw, T. J., Chow, C. K., & Laranjo, L. (2022) · JMIR Cardio · doi:10.2196/33839 · Cited by 55
“Given the demonstrated benefits of self-management interventions more broadly [74] and remote monitoring [18-27], future research should explore the possibility that their combination may result in synergistic effects and higher efficacy in improving heart failure outcomes.”
BackgroundResultInfluential
Health Care Professionals’ Perceptions of Home Telemonitoring in Heart Failure Care: Cross-Sectional Survey
Aamodt, I. T., Lycholip, E., Celutkiene, J., Strömberg, A., Atar, D., Falk, R. S., von Lueder, T., Hellesø, R., Jaarsma, T., & Lie, I. (2019) · Journal of Medical Internet Research · doi:10.2196/10362 · Cited by 49
“Moreover, the cost of implementing TM in the management of HF is not clearly reported, varying from low-to-high cost depending on how costs are measured, for example, equipment, follow-up, or hospital admission [13,23,42].”
BackgroundResult
Design and Usability of a Heart Failure mHealth System: A Pilot Study
Alnosayan, N., Chatterjee, S., Alluhaidan, A. S., Lee, E., & Houston-Feenstra, L. (2017) · JMIR Human Factors · doi:10.2196/humanfactors.6481 · Cited by 56
“The various design approaches and inconsistent findings have resulted in the need to understand what features are effective and how users’ interaction with the system impacts adherence to the HF self-care process and, consequently, health outcomes [7,8].”
Development of an innovative mHealth platform for remote physical activity monitoring and health coaching of cardiac rehabilitation patients
Kitsiou, S., Thomas, M. M., Marai, G. E., Maglaveras, N., Kondos, G. T., Arena, R. A., & Gerber, B. S. (2017) · IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI ...) · doi:10.1109/bhi.2017.7897223 · Cited by 55
“sabbatical leave from Aristotle University, Lab of Computing and Medical Mobile health technologies (mHealth) such as smartphones, mobile applications (apps), and wearable activity tracking devices that permit real-time collection of “big data” have become ubiquitous [10], offering significant and innovative opportuni…”
BackgroundSelf-citation
Effectiveness of Telemonitoring in Obstetrics: Scoping Review
Lanssens, D., Vandenberk, T., Thijs, I. M. V., Grieten, L., & Gyselaers, W. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.7266 · Cited by 52
“A number of systematic reviews have evaluated the effectiveness of telemonitoring interventions for patients diagnosed with chronic cardiovascular disease (CVD), chronic obstructive pulmonary disease (COPD), and diabetes [2,5-8].”
Background
Effectiveness of telemonitoring on self-care behaviors among community-dwelling adults with heart failure: a quantitative systematic review
Nick, J. M., Roberts, L. R., & Petersen, A. B. (2021) · JBI Evidence Synthesis · doi:10.11124/jbies-20-00329 · Cited by 52
“A pivotal question remains: Is the effectiveness of TM due to increased provider interaction in response to alerts or due to patients’ increased ability to adjust self-care behaviors, or both? There is still a need for greater understanding of the mechanism by which TM improves outcomes.(84) Existing theoretical model…”
Background
Effects of Different Telemonitoring Strategies on Chronic Heart Failure Care: Systematic Review and Subgroup Meta-Analysis
Ding, H., Chen, S. H., Edwards, I., Jayasena, R., Doecke, J. D., Layland, J. J., Yang, I. A., & Maiorana, A. (2020) · Journal of Medical Internet Research · doi:10.2196/20032 · Cited by 49
“Over the past two decades, many enabled care programs have been developed and evaluated, and several reviews have demonstrated the potential of using telemonitoring interventions to reduce mortality [9-11] and hospitalizations [9,11] in CHF care.”
Background
Factors Affecting the Acceptance of Telehealth Services by Heart Failure Patients: An Integrative Review
Woo, K., & Dowding, D. (2017) · Telemedicine Journal and e-Health · doi:10.1089/tmj.2017.0080 · Cited by 47
“A recent meta-analysis of 15 systematic reviews published between 2003 and 2013 indicates that telehealth reduces HF-related hospital admissions comparedwithusual care.(9) In addition, amore recent study reports a significant reduction, from 19.”
Background
Effects of a Tablet Computer on Self-care, Quality of Life, and Knowledge
Melin, M., Hägglund, E., Ullman, B., Persson, H., & Hagerman, I. (2018) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0000000000000462 · Cited by 47
Clinical outcomes of digital sensor alerting systems in remote monitoring: a systematic review and meta-analysis
Iqbal, F. M., Lam, K., Joshi, M., Khan, S. N., Ashrafian, H., & Darzi, A. W. (2021) · npj Digital Medicine · doi:10.1038/s41746-020-00378-0 · Cited by 46
Home Telemonitoring of Community-Dwelling Heart Failure Patients After Home Care Discharge
Nouryan, C. N., Morahan, S., Pecinka, K., Akerman, M. B., LESSER, M. L., Chaikin, D., Castillo, S., Zhang, M., & Pekmezaris, R. (2018) · Telemedicine Journal and e-Health · doi:10.1089/tmj.2018.0099 · Cited by 45
“85) compared with usual care.(14,15) This review also found a great deal of variability in outcomes associated with home telehealth technology, specifically finding that only telemonitoring using mobile or automated devices effectively reduced the risk of HF-related hospitalizations and all-cause mortality, as opposed…”
Telehealth in chronic disease management and the role of the Internet-of-Medical-Things: the Tholomeus® experience
Omboni, S., Campolo, L., & Panzeri, E. (2020) · Expert Review of Medical Devices · doi:10.1080/17434440.2020.1782734 · Cited by 45
Home telemonitoring for chronic disease management: Perceptions of users and factors influencing adoption
Li, J., Varnfield, M., Jayasena, R., & Celler, B. G. (2021) · Health Informatics Journal · doi:10.1177/1460458221997893 · Cited by 50
Guidelines os the Brazilian Society of Cardiology on Telemedicine in Cardiology - 2019
Lopes, M. A. C. Q., de Oliveira, G. M. M., Ribeiro, A. L. P., Pinto, F. J., Rey, H. C. V., o, A. ́. A. ́. B., Zimerman, L. I., Hajjar, L. A., Rochitte, C. E., Bacal, F., et al. (2019) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.20190205 · Cited by 50
Non-Invasive Home Telemonitoring in Patients with Decompensated Heart Failure: A Systematic Review and Meta-Analysis
Drews, T. E. I., Laukkanen, J. A., & Nieminen, T. V. M. (2021) · ESC Heart Failure · doi:10.1002/ehf2.13475 · Cited by 51
“reasons.(12,23) Previous meta-analyses and reviews have mostly included various approaches of telehealth interventions among HF patients.”
Background
Enablers and barriers in upscaling telemonitoring across geographic boundaries: a scoping review
Gijsbers, H., Feenstra, T. M., Eminovic, N., van Dam, D., Nurmohamed, S. A., van de Belt, T., & Schijven, M. P. (2022) · BMJ Open · doi:10.1136/bmjopen-2021-057494 · Cited by 37
The Use of Telehealth to Reduce Inequalities in Cardiovascular Outcomes in Australia and New Zealand: A Critical Review
Wade, V., & Stocks, N. P. (2016) · Heart Lung and Circulation · doi:10.1016/j.hlc.2016.10.013 · Cited by 41
Remote Surveillance Technologies: Realizing the Aim of Right Patient, Right Data, Right Time
Safavi, K. C., Driscoll, W. D., & Wiener-Kronish, J. P. (2018) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000003948 · Cited by 42
Systematic reviews and meta-analyses on psoriasis: role of funding sources, conflict of interest and bibliometric indices as predictors of methodological quality
Gómez-García, F. J., Ruano, J., Aguilar-Luque, M., Gay-Mimbrera, J., Maestre-López, B., Sanz-Cabanillas, J. L., Carmona-Fernández, P. J., González-Padilla, M., García-Nieto, A. J. V., & Isla-Tejera, B. (2017) · British Journal of Dermatology · doi:10.1111/bjd.15380 · Cited by 39
Examining How Chronically Ill Patients’ Reactions to and Effective Use of Information Technology Can Influence How Well They Self-Manage Their Illness
Savoli, A., Barki, H., & Paré, G. (2020) · MIS Quarterly · doi:10.25300/misq/2020/15103 · Cited by 43
Self-citation
Digital Health Applications in Heart Failure: a Critical Appraisal of Literature
Farwati, M., Riaz, H., & Tang, W. H. W. (2021) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-020-00885-z · Cited by 37
Evidence and User Considerations of Home Health Monitoring for Older Adults: Scoping Review
Chan, A., Cohen, R., Robinson, K.-M., Bhardwaj, D., Gregson, G., Jutai, J. W., Millar, J., Rincon, A. M. R., & Fekr, A. R. (2022) · JMIR Aging · doi:10.2196/40079 · Cited by 41
“First, the evidence remains siloed within disease-specific reviews or secondary prevention, whether in heart failure [22,23], chronic obstructive pulmonary disease (COPD) [24], diabetes [25], or cardiometabolic health [26], making it difficult to compare effective monitoring models, delineate the overall evidence for…”
Background
Smartphone Ownership and Interest in Mobile Health Technologies for Self-care Among Patients With Chronic Heart Failure: Cross-sectional Survey Study
Leigh, J. W., Gerber, B. S., Gans, C. P., Kansal, M. M., & Kitsiou, S. (2021) · JMIR Cardio · doi:10.2196/31982 · Cited by 41
“Several systematic reviews and meta-analyses have demonstrated the efficacy of mHealth interventions for self-management of long-term conditions (eg, HF [27,28], diabetes [29,30], and hypertension [31]).”
BackgroundSelf-citation
A prospective evaluation of telemonitoring use by seniors with chronic heart failure: Adoption, self-care, and empowerment
Jaana, M., Sherrard, H., & Paré, G. (2018) · Health Informatics Journal · doi:10.1177/1460458218799458 · Cited by 37
Self-citation
Enabling Guidelines for the Adoption of eHealth Solutions: Scoping Review
Støme, L. N., Wilhelmsen, C. R., & Kværner, K. J. (2021) · JMIR Formative Research · doi:10.2196/21357 · Cited by 39
“US Strategic analysis Scaling Multifaceted Cardiovascular disease Kitsiou et al (2015) [37]”
BackgroundMethodInfluential
Acute Heart Failure
Zsilinszka, R., Mentz, R. J., DeVore, A. D., Eapen, Z. J., Pang, P. S., & Hernandez, A. F. (2017) · JACC Heart Failure · doi:10.1016/j.jchf.2016.12.014 · Cited by 35
From Elements to Structures: An Agenda for Organisational Gamification
Khan, A., Boroomand, F., Webster, J., & Minocher, X. (2020) · European Journal of Information Systems · doi:10.1080/0960085x.2020.1780963 · Cited by 37
“…advantages such as summarizing research teams’ views of the evidence in an area (Aromataris et al., 2015), the review articles making up the umbrella review do not represent independent observations (Kitsiou et al., 2015) and need to be interpreted at a broad level (Aromataris et al., 2015).”
Background
Practice Patterns and Patient Outcomes After Widespread Adoption of Remote Heart Failure Care
Yuan, N., Botting, P. G., Elad, Y., Miller, S. J., Cheng, S. C., Ebinger, J. E., & Kittleson, M. M. (2021) · Circulation Heart Failure · doi:10.1161/circheartfailure.121.008573 · Cited by 34
Effect of post-discharge virtual wards on improving outcomes in heart failure and non-heart failure populations: A systematic review and meta-analysis
Uminski, K., Komenda, P. V. J., Whitlock, R. H., Ferguson, T. W., Nadurak, S., Hochheim, L., Tangri, N., & Rigatto, C. (2018) · PLoS ONE · doi:10.1371/journal.pone.0196114 · Cited by 33
Telemonitoring in-home complex chronic patients from primary care in routine clinical practice: Impact on healthcare resources use
Lesende, I. M., Orruño, E., Mateos, M., Recalde, E., Asua, J., Reviriego, E., & Bayón, J. C. (2017) · European Journal of General Practice · doi:10.1080/13814788.2017.1306516 · Cited by 33
“Several randomized controlled trials (RCT) and systematic reviews with or without meta-analyses [1–10] have been recently published regarding the utility of telemonitoring in reducing hospital admissions and mortality [1,2,4,8,9] in HF, and in decreasing admissions in COPD patients [7,10].”
Background
Cascading Feedback: A Longitudinal Study of a Feedback Ecosystem for Telemonitoring Patients with Chronic Disease
Brohman, M. K., Addas, S., Dixon, J., & Pinsonneault, A. (2020) · MIS Quarterly · doi:10.25300/misq/2020/15089 · Cited by 44
Clinical Efficiency and Safety Outcomes of Virtual Care for Oncology Patients During the COVID-19 Pandemic
Hsiehchen, D., Muquith, M., Haque, W. Z., Espinoza, M., Yopp, A. C., & Beg, M. S. (2021) · JCO Oncology Practice · doi:10.1200/op.21.00092 · Cited by 32
“273 Time to therapy initiation, median (IQR), days 17 (12-28) 15 (10-21) 18 (12-28) 15 (10-21) .”
Patterns of emergency department utilization by patients on chronic dialysis: A population-based study
Komenda, P. V. J., Tangri, N., Klajncar, E., Eng, A., Nella, M. D., Hiebert, B. M., Strome, T., de Faria, R. L., Zacharias, J., Verrelli, M., et al. (2018) · PLoS ONE · doi:10.1371/journal.pone.0195323 · Cited by 29
A Systematic Review of the Usability of Telemedicine Interface Design for Older Adults
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“These groups reflect the existence of ‘major’, ‘moderate’ and ‘minor or no methodological limitations’ in a SR. 32 Similar categorisation of methodological quality have been used in other overviews of SRs (eg, studies include Kitsiou et al, Jaspers et al and Sequeira-Byron et al 33–35 ).”
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“These interventions range from structured telephone support and noninvasive home telemonitoring [23,24] to remote patient monitoring (RPM) with implantable devices [25,26] and, more recently, the use of mobile health (mHealth) technologies for patient education [27] and HF self-care support…”
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“For example, remote monitoring of medication adherence (Hale et al., 2016) or relevant clinical metrics (e.g., blood pressure, weight; Agboola et al., 2015; Hudson et al., 2005) have improved clinical outcomes for patients with congestive heart failure (review, Kitsiou et al., 2015).”
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Authors: Kitsiou, S., Paré, G., & Jaana, M.
Affiliations: University of Illinois Chicago (US)
HEC Montréal (CA)
University of Ottawa (CA)
Corresponding author: Kitsiou, Spyros
ORCID: Kitsiou, Spyros
Paré, Guy
Jaana, Mirou
Venue: Journal of Medical Internet Research
Publisher: JMIR Publications Inc.
Published: 2015-03-12
Volume: 17
Issue: 3
Pages: e63
ISSN: 1438-8871 (ISSN-L)
DOI: 10.2196/jmir.4174
PMC: PMC4376138
OpenAlex: W2074454475
Semantic Scholar: 498b1218d10c77894f3f577d87d5854f58e95106
Cited by: 327
References: 79
Citations by year: 2026: 26 · 2025: 28 · 2024: 23 · 2023: 39 · 2022: 23 · 2021: 40 · 2020: 38 · 2019: 19 · 2018: 26 · 2017: 39 · 2016: 15 · 2015: 11
FWCI: 4.37
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
Locations: Journal of Medical Internet Research (publishedVersion, cc-by)
Europe PMC (PubMed Central) (publishedVersion, cc-by)
PubMed Central (publishedVersion, cc-by)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders: McMaster University
Canada Research Chairs
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Telemedicine and Telehealth Implementation
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
Keywords: home health monitoring, chronic heart failure, heart failure hospitalization, all-cause mortality, methodological quality of systematic reviews, AMSTAR, GRADE quality of evidence, heart failure exacerbation, patient-reported outcomes, quality of life, health-related quality of life, patient satisfaction
MeSH terms: Chronic Disease, Heart Failure, Hospitalization, Humans, Monitoring, Physiologic, Review Literature as Topic, Telemetry, Meta-Analysis as Topic, Telemedicine

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Effects of Home Telemonitoring Interventions on Patients With Chronic Heart Failure: An Overview of Systematic Reviews

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