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Important Shapeshifter: Mechanisms Allowing Astrocytes to Respond to the Changing Nervous System During Development, Injury and Disease
Open accessAbstract
Astrocytes are the most prevalent glial cells in the brain. Historically considered as "merely supporting" neurons, recent research has shown that astrocytes actively participate in a large variety of central nervous system (CNS) functions including synaptogenesis, neuronal transmission and synaptic plasticity. During disease and injury, astrocytes efficiently protect neurons by various means, notably by sealing them off from neurotoxic factors and repairing the blood-brain barrier. Their ramified morphology allows them to perform diverse tasks by interacting with synapses, blood vessels and other glial cells. In this review article, we provide an overview of how astrocytes acquire their complex morphology during development. We then move from the developing to the mature brain, and review current research on perisynaptic astrocytic processes, with a particular focus on how astrocytes engage synapses and modulate their formation and activity. Comprehensive changes have been reported in astrocyte cell shape in many CNS pathologies. Factors influencing these morphological changes are summarized in the context of brain pathologies, such as traumatic injury and degenerative conditions. We provide insight into the molecular, cellular and cytoskeletal machinery behind these shape changes which drive the dynamic remodeling in astrocyte morphology during injury and the development of pathologies.
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“Thorough visualization is necessary because astrocytes undergo distinct morphological changes other than hypertrophy in pathological contexts, including elongation, process extension toward injury site, and some three-dimensional (3D) domain overlap26.”
From Reactive astrocyte nomenclature, definitions, and future directions (2021) · cites this paper as [26]
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Cites
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
Nimmerjahn, A., Kirchhoff, F., & Helmchen, F. (2005) · Science · doi:10.1126/science.1110647 · Cited by 5,827
Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue.
McCarthy, K. D., & de Vellis, J. (1980) · The Journal of Cell Biology · doi:10.1083/jcb.85.3.890 · Cited by 3,825
Daneman, R., & Prat, A. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020412 · Cited by 3,437
Molecular dissection of reactive astrogliosis and glial scar formation
Sofroniew, M. V. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.08.002 · Cited by 2,594
Tripartite synapses: glia, the unacknowledged partner
Araque, A., Parpura, V., Sanzgiri, R. P., & Haydon, P. G. (1999) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01349-6 · Cited by 2,529
Astrocyte scar formation aids central nervous system axon regeneration
Anderson, M. A., Burda, J. E., Ren, Y., Ao, Y., O’Shea, T. M., Kawaguchi, R., Coppola, G., Khakh, B. S., Deming, T. J., & Sofroniew, M. V. (2016) · Nature · doi:10.1038/nature17623 · Cited by 1,851
Synaptic scaling mediated by glial TNF-α
Stellwagen, D., & Malenka, R. C. (2006) · Nature · doi:10.1038/nature04671 · Cited by 1,715
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis
Christopherson, K. S., Ullian, E. M., Stokes, C. C. A., Mullowney, C. E., Hell, J. W., Agah, A., Lawler, J., Mosher, D. F., Bornstein, P., & Barres, B. A. (2005) · Cell · doi:10.1016/j.cell.2004.12.020 · Cited by 1,688
Reactive Astrocytes Protect Tissue and Preserve Function after Spinal Cord Injury
Faulkner, J. R., Herrmann, J. E., Woo, M. J., Tansey, K. E., Doan, N., & Sofroniew, M. V. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3547-03.2004 · Cited by 1,652
Protoplasmic Astrocytes in CA1 Stratum Radiatum Occupy Separate Anatomical Domains
Bushong, E. A., Martone, M. E., Jones, Y. Z., & Ellisman, M. H. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-01-00183.2002 · Cited by 1,578
Uniquely Hominid Features of Adult Human Astrocytes
Oberheim, N. A., Takano, T., Han, X., He, W., Lin, J. H. C., Wang, F., Xu, Q., Wyatt, J. D., Pilcher, W., Ojemann, J. G., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4707-08.2009 · Cited by 1,488
Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways
Chung, W.-S., Clarke, L. E., Wang, G. X., Stafford, B. K., Sher, A., Chakraborty, C., Joung, J., Foo, L. C., Thompson, A., Chen, C., et al. (2013) · Nature · doi:10.1038/nature12776 · Cited by 1,377
Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth
Zhang, L., Zhang, S., Yao, J., Lowery, F. J., Zhang, Q., Huang, W.-C., Li, P., Li, M., Wang, X., Zhang, C., et al. (2015) · Nature · doi:10.1038/nature15376 · Cited by 1,175
Etienne-Manneville, S., & Hall, A. (2001) · Cell · doi:10.1016/s0092-8674(01)00471-8 · Cited by 941
Glia-Derived d-Serine Controls NMDA Receptor Activity and Synaptic Memory
Panatier, A., Theodosis, D. T., Mothet, J.-P., Touquet, B., Pollegioni, L., Poulain, D. A., & Oliet, S. H. R. (2006) · Cell · doi:10.1016/j.cell.2006.02.051 · Cited by 934
Mathiisen, T. M., Lehre, K. P., Danbolt, N. C., & Ottersen, O. (2010) · Glia · doi:10.1002/glia.20990 · Cited by 893
Wanner, I. B., Anderson, M. A., Song, B., Levine, J., Fernandez, A., Gray-Thompson, Z., Ao, Y., & Sofroniew, M. V. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2121-13.2013 · Cited by 839
Chaudhry, F. A., Lehre, K. P., Campagne, M. V. L., Ottersen, O. P., Danbolt, N. C., & Storm‐Mathisen, J. (1995) · Neuron · doi:10.1016/0896-6273(95)90158-2 · Cited by 838
Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity
Etienne-Manneville, S., & Hall, A. (2003) · Nature · doi:10.1038/nature01423 · Cited by 835
Astrocyte roles in traumatic brain injury
Burda, J. E., Bernstein, A. M., & Sofroniew, M. V. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.03.020 · Cited by 791
Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors
Allen, N. J., Bennett, M. L., Foo, L. C., Wang, G. X., Chakraborty, C., Smith, S. J., & Barres, B. A. (2012) · Nature · doi:10.1038/nature11059 · Cited by 764
Astrocytic complexity distinguishes the human brain
Oberheim, N. A., Wang, X., Goldman, S., & Nedergaard, M. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2006.08.004 · Cited by 739
The Growth Cone Cytoskeleton in Axon Outgrowth and GuidancePreprint
Dent, E. W., Gupton, S. L., & Gertler, F. B. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a001800 · Cited by 692
Functional regeneration beyond the glial scar
Cregg, J. M., DePaul, M. A., Filous, A. R., Lang, B. T., Tran, A. P., & Silver, J. (2014) · Experimental Neurology · doi:10.1016/j.expneurol.2013.12.024 · Cited by 688
Astrocytes and disease: a neurodevelopmental perspective
Molofsky, A. V., Krenick, R., Ullian, E., Tsai, H.-H., Deneen, B., Richardson, W. D., Barres, B. A., & Rowitch, D. H. (2012) · Genes & Development · doi:10.1101/gad.188326.112 · Cited by 682
Wilhelmsson, U., Bushong, E. A., Price, D. L., Smarr, B. L., Phung, V., Terada, M., Ellisman, M. H., & Pekny, M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602841103 · Cited by 643
Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC
Kucukdereli, H., Allen, N. J., Lee, A. T., Feng, A., Ozlu, M. I., Conatser, L. M., Chakraborty, C., Workman, G., Weaver, M., Sage, E. H., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1104977108 · Cited by 642
The neurobiology of glia in the context of water and ion homeostasis
Simard, M. F., & Nedergaard, M. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.09.053 · Cited by 640
Essential protective roles of reactive astrocytes in traumatic brain injury
Myer, D. J. (2006) · Brain · doi:10.1093/brain/awl165 · Cited by 637
The Sox9 transcription factor determines glial fate choice in the developing spinal cord
Stolt, C. C., Lommes, P., Sock, E., Chaboissier, M.-C., Schedl, A., & Wegner, M. (2003) · Genes & Development · doi:10.1101/gad.259003 · Cited by 636
Han, X., Chen, M., Wang, F., Windrem, M., Wang, S., Shanz, S., Xu, Q., Oberheim, N. A., Bekar, L., Betstadt, S., et al. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2012.12.015 · Cited by 635
Astrocyte-derived ATP modulates depressive-like behaviors
Cao, X., Li, L.-P., Wang, Q., Wu, Q., Hu, H.-H., Zhang, M., Fang, Y.-Y., Zhang, J., Li, S.-J., Xiong, W.-C., et al. (2013) · Nature Medicine · doi:10.1038/nm.3162 · Cited by 615
Rash, J. E., Yasumura, T., Hudson, C. S., Agre, P. C., & Nielsen, S. M. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.20.11981 · Cited by 609
Disruption of astrocyte–vascular coupling and the blood–brain barrier by invading glioma cells
Watkins, S., Robel, S., Kimbrough, I. F., Robert, S. M., Ellis‐Davies, G. C. R., & Sontheimer, H. W. (2014) · Nature Communications · doi:10.1038/ncomms5196 · Cited by 582
Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair
Tsai, H., Li, H., Fuentealba, L. C., Molofsky, A. V., Taveira‐Marques, R., Zhuang, H., Tenney, A., Murnen, A. T., Fancy, S. P. J., Merkle, F. T., et al. (2012) · Science · doi:10.1126/science.1222381 · Cited by 555
Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling
Murai, K. K., Nguyen, L. N., Irie, F., Yamaguchi, Y., & Pasquale, E. B. (2003) · Nature Neuroscience · doi:10.1038/nn994 · Cited by 516
Local generation of glia is a major astrocyte source in postnatal cortex
Ge, W.-P., Miyawaki, A., Gage, F. H., Jan, Y. N., & Jan, L. Y. (2012) · Nature · doi:10.1038/nature10959 · Cited by 507
Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis
Stogsdill, J. A., Ramirez, J., Liu, D., Kim, Y. H., Baldwin, K. T., Enustun, E., Ejikeme, T., Ji, R.-R., & Eroglu, C. (2017) · Nature · doi:10.1038/nature24638 · Cited by 506
Wu, C., Asokan, S. B., Berginski, M. E., Haynes, E. M., Sharpless, N. E., Griffith, J. D., Gomez, S. M., & Bear, J. E. (2012) · Cell · doi:10.1016/j.cell.2011.12.034 · Cited by 505
Involvement of aquaporin-4 in astroglial cell migration and glial scar formation
Saadoun, S., Papadopoulos, M. C., Watanabe, H., Yan, D., Manley, G. T., & Verkman, A. S. (2005) · Journal of Cell Science · doi:10.1242/jcs.02680 · Cited by 465
Bushong, E. A., Martone, M. E., & Ellisman, M. H. (2004) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2003.12.008 · Cited by 463
Wilhelmsson, U., Li, L., Pekna, M., Berthold, C.-H., Blom, S., Eliasson, C., Renner, O., Bushong, E., Ellisman, M., Morgan, T. E., et al. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.0820-04.2004 · Cited by 455
Elusive roles for reactive astrocytes in neurodegenerative diseases
Ben Haim, L., Carrillo-de Sauvage, M.-A., Ceyzériat, K., & Escartin, C. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00278 · Cited by 453
Deterministic Progenitor Behavior and Unitary Production of Neurons in the Neocortex
Gao, P., Postiglione, M. P., Krieger, T. G., Hernandez, L., Wang, C., Han, Z., Streicher, C., Papusheva, E., Insolera, R., Chugh, K., et al. (2014) · Cell · doi:10.1016/j.cell.2014.10.027 · Cited by 449
Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation
Bardehle, S., Krüger, M., Buggenthin, F., Schwausch, J., Ninkovic, J., Clevers, H. C., Snippert, H. J. G., Theis, F. J., Meyer‐Luehmann, M., Bechmann, I., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3371 · Cited by 448
Astrocyte Regulation of Blood Flow in the BrainPreprint
MacVicar, B. A., & Newman, E. A. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020388 · Cited by 443
Srinivasan, R., Lu, T.-Y., Chai, H., Xu, J., Huang, B. S., Golshani, P., Coppola, G., & Khakh, B. S. (2016) · Neuron · doi:10.1016/j.neuron.2016.11.030 · Cited by 443
Carter, S. F., Schöll, M., Almkvist, O., Wall, A., Engler, H., Långström, B., & Nordberg, A. (2012) · Journal of Nuclear Medicine · doi:10.2967/jnumed.110.087031 · Cited by 442
Development of a Method for the Purification and Culture of Rodent Astrocytes
Foo, L. C., Allen, N. J., Bushong, E. A., Ventura, P. B., Chung, W.-S., Zhou, L., Cahoy, J. D., Daneman, R., Zong, H., Ellisman, M. H., et al. (2011) · Neuron · doi:10.1016/j.neuron.2011.07.022 · Cited by 433
Sleep Loss Promotes Astrocytic Phagocytosis and Microglial Activation in Mouse Cerebral Cortex
Bellesi, M., de Vivo, L., Chini, M., Gilli, F., Tononi, G., & Cirelli, C. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3981-16.2017 · Cited by 431
Changing numbers of neuronal and non-neuronal cells underlie postnatal brain growth in the rat
Bandeira, F., Lent, R., & Herculano‐Houzel, S. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804650106 · Cited by 427
Pekny, M., Johansson, C. B., Eliasson, C., Stakeberg, J., Wallén, Å., Perlmann, T., Lendahl, U., Betsholtz, C., Berthold, C.-H., & Frisén, J. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.145.3.503 · Cited by 405
Self‐organized developmental patterning and differentiation in cerebral organoids
Renner, M., Lancaster, M. A., Bian, S., Choi, H., Ku, T., Peer, A., Chung, K., & Knoblich, J. A. (2017) · The EMBO Journal · doi:10.15252/embj.201694700 · Cited by 389
Astroglial networks scale synaptic activity and plasticity
Pannasch, U., Vargová, L., Reingruber, J., Ezan, P., Holcman, D., Giaume, C., Syková, E., & Rouach, N. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016650108 · Cited by 383
Autocrine Factors That Sustain Glioma Invasion and Paracrine Biology in the Brain Microenvironment
Hoelzinger, D. B., Demuth, T., & Berens, M. E. (2007) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djm187 · Cited by 370
Bernardinelli, Y., Randall, J., Janett, E., Nikonenko, I., König, S., Jones, E. V., Flores, C. E., Murai, K. K., Bochet, C. G., Holtmaat, A., et al. (2014) · Current Biology · doi:10.1016/j.cub.2014.06.025 · Cited by 369
Developmental and Evolutionary Adaptations of Cortical Radial Glia
RAKIC, P. T. (2003) · Cerebral Cortex · doi:10.1093/cercor/13.6.541 · Cited by 346
Synapse-specific astrocyte gating of amygdala-related behavior
Martin-Fernandez, M., Jamison, S., Robin, L. M., Zhao, Z., Martin, E. D., Aguilar, J., Benneyworth, M. A., Marsicano, G., & Araque, A. (2017) · Nature Neuroscience · doi:10.1038/nn.4649 · Cited by 345
The Two Patterns of Reactive Astrocytosis in Postischemic Rat Brain
Petito, C. K., Morgello, S., Felix, J. C., & LESSER, M. L. (1990) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1990.141 · Cited by 337
Pekny, M., Levéen, P., Pekna, M., Eliasson, C., Berthold, C. H., Westermark, B., & Betsholtz, C. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07147.x · Cited by 336
Hochstim, C., Deneen, B., Lukaszewicz, A., Zhou, Q., & Anderson, D. J. (2008) · Cell · doi:10.1016/j.cell.2008.02.046 · Cited by 331
Connexin 30 sets synaptic strength by controlling astroglial synapse invasion
Pannasch, U., Freche, D., Dallérac, G. M., Ghézali, G., Escartin, C., Ezan, P., Cohen‐Salmon, M., Benchenane, K., Abudara, V., Dufour, A., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3662 · Cited by 329
Ren, Z., Iliff, J. J., Yang, L., Yang, J., Chen, X., Chen, M. J., Giese, R. N., Wang, B., Shi, X., & Nedergaard, M. (2013) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2013.30 · Cited by 317
Higashi, K., Fujita, A., Inanobe, A., Tanemoto, M., Doi, K., Kubo, T., & Kurachi, Y. (2001) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.2001.281.3.c922 · Cited by 310
Heneka, M. T., Sastre, M., Dumitrescu-Ozimek, L., Dewachter, I., Walter, J., Klockgether, T., & Van Leuven, F. (2005) · Journal of Neuroinflammation · doi:10.1186/1742-2094-2-22 · Cited by 309
Plasticity of perisynaptic astroglia during synaptogenesis in the mature rat hippocampus
Witcher, M. R., Kirov, S. A., & Harris, K. M. (2006) · Glia · doi:10.1002/glia.20415 · Cited by 306
Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA
Schousboe, A., Bak, L. K., & Waagepetersen, H. S. (2013) · Frontiers in Endocrinology · doi:10.3389/fendo.2013.00102 · Cited by 303
Astroglial processes show spontaneous motility at active synaptic terminals in situ
Hirrlinger, J., Hülsmann, S., & Kirchhoff, F. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03689.x · Cited by 301
Actin assembly mechanisms at a glance
Rottner, K., Faix, J., Bogdan, S., Linder, S., & Kerkhoff, E. (2017) · Journal of Cell Science · doi:10.1242/jcs.206433 · Cited by 298
Korobova, F. V., & Svitkina, T. (2008) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-09-0964 · Cited by 291
MICROTUBULES AND FILAMENTS IN THE AXONS AND ASTROCYTES OF EARLY POSTNATAL RAT OPTIC NERVES
Peters, A., & Vaughn, J. E. (1967) · The Journal of Cell Biology · doi:10.1083/jcb.32.1.113 · Cited by 285
Lavialle, M., Aumann, G., Anlauf, E., Pröls, F., Arpin, M., & Derouiche, A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1100957108 · Cited by 283
Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport
Filosa, A., Paixão, S., Honsek, S. D., Carmona, M. A., Becker, L., Feddersen, B., Gaitanos, L., Rudhard, Y., Schoepfer, R., Klopstock, T., et al. (2009) · Nature Neuroscience · doi:10.1038/nn.2394 · Cited by 283
Structural and Functional Plasticity of Astrocyte Processes and Dendritic Spine Interactions
Perez-Alvarez, A., Navarrete, M., Covelo, A., Martin, E. D., & Araque, A. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.2401-14.2014 · Cited by 280
Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling
Farmer, W. T., Abrahamsson, T., Chierzi, S., Lui, C. G., Zaelzer, C. A., Jones, E. V., Bally, B. P., Chen, G. G., Théroux, J., Peng, J., et al. (2016) · Science · doi:10.1126/science.aab3103 · Cited by 270
Direct Astrocytic Contacts Regulate Local Maturation of Dendritic Spines
西田, 秀., & Okabe, S. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4466-06.2007 · Cited by 268
Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways
Rotty, J. D., Wu, C., Haynes, E. M., Suarez, C., Winkelman, J. D., Johnson, H. E., Haugh, J. M., Kovar, D. R., & Bear, J. E. (2014) · Developmental Cell · doi:10.1016/j.devcel.2014.10.026 · Cited by 263
Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia
Windrem, M. S., Osipovitch, M., Liu, Z., Bates, J., Chandler-Militello, D., Zou, L., Munir, J., Schanz, S. J., McCoy, K., Miller, R. H., et al. (2017) · Cell stem cell · doi:10.1016/j.stem.2017.06.012 · Cited by 259
Kamphuis, W., Middeldorp, J., Kooijman, L., Sluijs, J. A., Kooi, E., Moeton, M., Freriks, M., Mizee, M. R., & Hol, E. M. (2013) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2013.09.035 · Cited by 251
The problem of astrocyte identity
Kimelberg, H. K. (2004) · Neurochemistry International · doi:10.1016/j.neuint.2003.08.015 · Cited by 244
Gan, Z., Ding, L., Burckhardt, C. J., Lowery, J., Zaritsky, A., Sitterley, K., Mota, A. L., Costigliola, N., Starker, C. G., Voytas, D. F., et al. (2016) · Cell Systems · doi:10.1016/j.cels.2016.08.007 · Cited by 242
Ledeboer, A., Brev�, J. J. P., Poole, S., Tilders, F. J. H., & van Dam, A. (2000) · Glia · doi:10.1002/(sici)1098-1136(200004)30:2 · Cited by 233
Theodosis, D. T. (2002) · Frontiers in Neuroendocrinology · doi:10.1006/frne.2001.0226 · Cited by 231
Stork, T., Sheehan, A. E., Tasdemir-Yilmaz, O. E., & Freeman, M. (2014) · Neuron · doi:10.1016/j.neuron.2014.06.026 · Cited by 230
Pten Loss Causes Hypertrophy and Increased Proliferation of Astrocytes In vivo
Fraser, M. M., Zhu, X., Kwon, C.-H., Uhlmann, E. J., Gutmann, D. H., & Baker, S. J. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-2487 · Cited by 219
Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport
Carmona, M. A., Murai, K. K., Wang, L., Roberts, A. J., & Pasquale, E. B. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903328106 · Cited by 216
Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA
Jiu, Y., Peränen, J., Schaible, N., Cheng, F., Eriksson, J., Krishnan, R., & Lappalainen, P. (2017) · Journal of Cell Science · doi:10.1242/jcs.196881 · Cited by 213
Cdc42 localization and cell polarity depend on membrane traffic
Osmani, N., Péglion, F., Chavrier, P., & Etienne‐Manneville, S. (2010) · The Journal of Cell Biology · doi:10.1083/jcb.201003091 · Cited by 207
Liu, Z., Li, Y., Cui, Y., Roberts, C. J., Lü, M., Wilhelmsson, U., Pekny, M., & Chopp, M. (2014) · Glia · doi:10.1002/glia.22723 · Cited by 205
Shapiro, D. L. (1973) · Nature · doi:10.1038/241203a0 · Cited by 205
Le, D. M., Besson, A., Fogg, D. K., Choi, K., Waisman, D. M., Goodyer, C. G., Rewcastle, B., & Yong, V. W. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-10-04034.2003 · Cited by 199
Derouiche, A., & Frotscher, M. (2001) · Glia · doi:10.1002/glia.1120 · Cited by 197
Butkevich, E., Hülsmann, S., Wenzel, D., Shirao, T., Duden, R., & Majoul, I. V. (2004) · Current Biology · doi:10.1016/j.cub.2004.03.063 · Cited by 190
Control of CNS Synapse Development by γ-Protocadherin-Mediated Astrocyte–Neuron Contact
Garrett, A. M., & Weiner, J. A. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.2818-09.2009 · Cited by 187
Ballistic labeling and dynamic imaging of astrocytes in organotypic hippocampal slice cultures.
Benediktsson, A., Schachtele, S., Green, S., & Dailey, M. E. (2005) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2004.05.013 · Cited by 186
Masahira, N., Takebayashi, H., Ono, K., Watanabe, K., Ding, L., Furusho, M., Ogawa, Y., Nabeshima, Y., Álvarez-Buylla, A., Shimizu, K., et al. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.02.029 · Cited by 182
Interleukin-1β Induces a Reactive Astroglial Phenotype via Deactivation of the Rho GTPase–Rock Axis
John, G. R., Chen, L., Rivieccio, M. A., Melendez‐Vasquez, C. V., Hartley, A., & Brosnan, C. F. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4789-03.2004 · Cited by 172
The Protein Phosphatase Activity of PTEN Regulates Src Family Kinases and Controls Glioma Migration
Dey, N., Crosswell, H. E., De, P. K. R., Parsons, R. E., Peng, Q., Su, J. D., & Durden, D. L. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-1182 · Cited by 170
Cytoskeleton and Vesicle Mobility in Astrocytes
Potokar, M., Kreft, M., Li, L., Andersson, D., Pangršič, T., Chowdhury, H. H., Pekny, M., & Zorec, R. (2006) · Traffic · doi:10.1111/j.1600-0854.2006.00509.x · Cited by 166
Ultrastructural localization of GLUT 1 and GLUT 3 glucose transporters in rat brain
Leino, R. L., Gerhart, D. Z., Bueren, A. M. V., McCall, A. L., & Drewes, L. R. (1997) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19970901)49:5 · Cited by 166
Astrocyte activation is suppressed in both normal and injured brain by FGF signaling
Kang, W., Balordi, F., Su, N. Y., Chen, L., Fishell, G., & Hébert, J. M. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1320401111 · Cited by 163
Molecular Logic of Neuronal Self-Recognition through Protocadherin Domain Interactions
Rubinstein, R., Thu, C. A., Goodman, K. M., Wolcott, H. N., Bahna, F. A., Mannepalli, S. M., Ahlsén, G., Chevée, M., Halim, A., Clausen, H., et al. (2015) · Cell · doi:10.1016/j.cell.2015.09.026 · Cited by 162
Kulijewicz‐Nawrot, M., Verkhratsky, A., Chvátal, A., Syková, E., & Rodríguez, J. J. (2012) · Journal of Anatomy · doi:10.1111/j.1469-7580.2012.01536.x · Cited by 160
Mechanisms of Astrocyte-Mediated Cerebral Edema
Stokum, J. A., Kurland, D. B., Gerzanich, V., & Simard, J. M. (2014) · Neurochemical Research · doi:10.1007/s11064-014-1374-3 · Cited by 158
Regulation of Astrocyte Morphology by RhoA and Lysophosphatidic Acid
Ramakers, G. J. A., & Moolenaar, W. H. (1998) · Experimental Cell Research · doi:10.1006/excr.1998.4224 · Cited by 150
Kanemaru, K., Kubota, J., Sekiya, H., Hirose, K., Okubo, Y., & Iino, M. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1300378110 · Cited by 147
Vimentin fibers orient traction stress
Costigliola, N., Ding, L., Burckhardt, C. J., Han, S. J., Gutierrez, E., Mota, A. L., Groisman, A., Mitchison, T. J., & Danuser, G. M. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1614610114 · Cited by 143
Jockusch, B. M., Murk, K., & Rothkegel, M. (2007) · Springer eBooks · doi:10.1007/112_2007_704 · Cited by 142
Self-citationBoyl, P. P., Nardo, A. D., Mulle, C., Sassoé‐Pognetto, M., Panzanelli, P., Mele, A., Kneussel, M., Costantini, V. J. A., Perlas, E., Massimi, M., et al. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601737 · Cited by 140
Stage-dependent fate determination of neural precursor cells in mouse forebrain
Hirabayashi, Y., & Gotoh, Y. (2005) · Neuroscience Research · doi:10.1016/j.neures.2005.01.004 · Cited by 137
Glia-derived ATP inversely regulates excitability of pyramidal and CCK-positive neurons
Tan, Z., Liu, Y., Wang, X., Lou, H., Zhu, L., Guo, Z., Mei, L., & Duan, S. (2017) · Nature Communications · doi:10.1038/ncomms13772 · Cited by 134
Etienne‐Manneville, S. (2006) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(06)06044-7 · Cited by 121
Warth, A., Mittelbronn, M. G. A., & Wolburg, H. (2005) · Acta Neuropathologica · doi:10.1007/s00401-005-0984-x · Cited by 121
Zbtb20 promotes astrocytogenesis during neocortical development
Nagao, M., Ogata, T., Sawada, Y., & Gotoh, Y. (2016) · Nature Communications · doi:10.1038/ncomms11102 · Cited by 121
Conditional deletion of β1‐integrin in astroglia causes partial reactive gliosis
Robel, S., Mori, T., Zoubaa, S., Schlegel, J., Sirko, S., Faissner, A., Goebbels, S., Dimou, L., & Götz, M. (2009) · Glia · doi:10.1002/glia.20876 · Cited by 120
A star is born: new insights into the mechanism of astrogenesis
Kanski, R., van Strien, M. E., van Tijn, P., & Hol, E. M. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1435-9 · Cited by 119
Cytoplasmic intermediate filaments mediate actin-driven positioning of the nucleus
Dupin, I., Sakamoto, Y., & Etienne‐Manneville, S. (2011) · Journal of Cell Science · doi:10.1242/jcs.076356 · Cited by 114
Glia selectively approach synapses on thin dendritic spines
Medvedev, N. I., Popov, V. I., Henneberger, C., Kraev, I., Rusakov, D. A., & Stewart, M. G. (2014) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2014.0047 · Cited by 112
de Pablo, Y., Nilsson, M., Pekna, M., & Pekny, M. (2013) · Histochemistry and Cell Biology · doi:10.1007/s00418-013-1110-0 · Cited by 111
Microtubule involvement in NIH 3T3 Golgi and MTOC polarity establishment
Magdalena, J., Millard, T. H., & Machesky, L. M. (2003) · Journal of Cell Science · doi:10.1242/jcs.00288 · Cited by 110
Regulation of microtubule-associated motors drives intermediate filament network polarization
Leduc, C., & Etienne‐Manneville, S. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201607045 · Cited by 108
Theodosis, D. T., Piet, R., Poulain, D. A., & Oliet, S. H. R. (2004) · Neurochemistry International · doi:10.1016/j.neuint.2003.11.003 · Cited by 105
Pekny, M., Eliasson, C., Chien, C. L., Kindblom, L. G., Liem, R. K. H., Hamberger, A., & Betsholtz, C. (1998) · Experimental Cell Research · doi:10.1006/excr.1997.3922 · Cited by 102
The Role of Attenuated Astrocyte Activation in Infantile Neuronal Ceroid Lipofuscinosis
Macauley, S. L., Pekny, M., & Sands, M. S. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.3579-11.2011 · Cited by 102
Homophilic Protocadherin Cell-Cell Interactions Promote Dendrite Complexity
Molumby, M. J., Keeler, A. B., & Weiner, J. A. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.03.093 · Cited by 100
APC binds intermediate filaments and is required for their reorganization during cell migration
Sakamoto, Y., Boëda, B., & Etienne‐Manneville, S. (2013) · The Journal of Cell Biology · doi:10.1083/jcb.201206010 · Cited by 98
Robel, S., Bardehle, S., Lepier, A., Brakebusch, C., & Götz, M. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2696-11.2011 · Cited by 95
Moonen, G., Heinen, E., & Goessens, G. (1976) · Cell and Tissue Research · doi:10.1007/bf00224329 · Cited by 93
Glia delimit shape changes of sensory neuron receptive endings in C. elegans
Procko, C., Lu, Y., & Shaham, S. (2011) · Development · doi:10.1242/dev.058305 · Cited by 92
Kreis, P., Leondaritis, G., Lieberam, I., & Eickholt, B. J. (2014) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2014.00023 · Cited by 87
Self-citationLate Origin of Glia-Restricted Progenitors in the Developing Mouse Cerebral Cortex
Costa, M. R., Bucholz, O., Schroeder, T., & Götz, M. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp046 · Cited by 86
Regulation of RhoA by STAT3 coordinates glial scar formation
Renault-Mihara, F., Mukaino, M., Shinozaki, M., Kumamaru, H., Kawase, S., Baudoux, M., Ishibashi, T., Kawabata, S., Nishiyama, Y., Sugai, K., et al. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201610102 · Cited by 82
Direct Thy-1/αVβ3 integrin interaction mediates neuron to astrocyte communication
Hermosilla, T., Muñoz, D., Herrera‐Molina, R., Valdivia, A., Muñoz, N., Nham, S.-U., Schneider, P., Burridge, K., Quest, A. F. G., & Leyton, L. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2008.01.034 · Cited by 78
γ-Protocadherins Interact with Neuroligin-1 and Negatively Regulate Dendritic Spine Morphogenesis
Molumby, M. J., Anderson, R. M., Newbold, D. J., Koblesky, N. K., Garrett, A. M., Schreiner, D., Radley, J. J., & Weiner, J. A. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.02.060 · Cited by 78
Actin cytoskeleton remodeling governs aquaporin‐4 localization in astrocytes
Nicchia, G. P., Rossi, A., Mola, M. G., Procino, G., Frigeri, A., & Svelto, M. (2008) · Glia · doi:10.1002/glia.20724 · Cited by 76
Fine-tuning of neuronal architecture requires two profilin isoforms
Michaelsen, K., Murk, K., Zagrebelsky, M., Dreznjak, A., Jockusch, B. M., Rothkegel, M., & Körte, M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1004406107 · Cited by 76
Self-citationRacchetti, G., D’Alessandro, R., & Meldolesi, J. (2011) · Glia · doi:10.1002/glia.22280 · Cited by 75
Inducible targeting of CNS astrocytes in Aldh1l1-CreERT2 BAC transgenic mice
Winchenbach, J., Düking, T., Berghoff, S. A., Stumpf, S. K., Hülsmann, S., Nave, K.-A., & Saher, G. (2016) · F1000Research · doi:10.12688/f1000research.10509.1 · Cited by 74
Disruption of astroglial interlaminar processes in Alzheimer’s disease.
Colombo, J. A., Quinn, B., & Puissant, V (2002) · Brain Research Bulletin · doi:10.1016/s0361-9230(02)00785-2 · Cited by 71
Protocadherins branch out: Multiple roles in dendrite development
Keeler, A. B., Molumby, M. J., & Weiner, J. A. (2015) · Cell Adhesion & Migration · doi:10.1080/19336918.2014.1000069 · Cited by 70
Calcium-induced outgrowth of astrocytic peripheral processes requires actin binding by Profilin-1
Molotkov, D., Николаевна, З. С., Arcas, J. M., & Khiroug, L. (2013) · Cell Calcium · doi:10.1016/j.ceca.2013.03.001 · Cited by 69
BMP Signaling in Astrocytes Downregulates EGFR to Modulate Survival and Maturation
Scholze, A. R., Foo, L. C., Mulinyawe, S. B., & Barres, B. A. (2014) · PLoS ONE · doi:10.1371/journal.pone.0110668 · Cited by 64
Microtubule-targeting-dependent reorganization of filopodia
Schober, J. M., Komarova, Y. A., Chaga, O. Y., Akhmanova, A. S., & Borisy, G. G. (2007) · Journal of Cell Science · doi:10.1242/jcs.003913 · Cited by 62
Post-translational Modifications of OLIG2 Regulate Glioma Invasion through the TGF-β Pathway
Singh, S. K., Fiorelli, R., Kupp, R., Rajan, S., Szeto, E., Cascio, C. L., Maire, C. L., Sun, Y., Alberta, J. A., Eschbacher, J. M., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.06.045 · Cited by 60
A critical role for palladin in astrocyte morphology and response to injury
Boukhelifa, M. (2003) · Molecular and Cellular Neuroscience · doi:10.1016/s1044-7431(03)00127-1 · Cited by 59
Murk, K., Blanco‐Suárez, E., Cockbill, L. M. R., Banks, P. J., & Hanley, J. G. (2013) · Journal of Cell Science · doi:10.1242/jcs.125146 · Cited by 59
Self-citation3D Electrospun scaffolds promote a cytotrophic phenotype of cultured primary astrocytes
Lau, C. L., Kovacevic, M., Tingleff, T. S., Forsythe, J. S., Cate, H. S., Merlo, D., Cederfur, C., Maclean, F. L., Parish, C. L., Horne, M. K., et al. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.12702 · Cited by 56
Control of Astrocyte Migration in the Developing Cerebral Cortex
Jacobsen, C. T., & Miller, R. H. (2003) · Developmental Neuroscience · doi:10.1159/000072269 · Cited by 54
Glioma-induced remodeling of the neurovascular unit
Lee, J., Lund-Smith, C., Borboa, A. K., Gonzalez, A. M., Baird, A., & Eliceiri, B. P. (2009) · Brain Research · doi:10.1016/j.brainres.2009.06.095 · Cited by 53
Genetic defects disrupting glial ion and water homeostasis in the brain
Min, R., & van der Knaap, M. S. (2018) · Brain Pathology · doi:10.1111/bpa.12602 · Cited by 53
Goetschy, J., Ulrich, G., Aunis, D., & Ciesielski-Treska, J. (1986) · Journal of Neurocytology · doi:10.1007/bf01611439 · Cited by 51
Haseleu, J., Anlauf, E., Blaess, S., Endl, E., & Derouiche, A. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00054 · Cited by 49
Berg, A., Zelano, J., Pekna, M., Wilhelmsson, U., Pekny, M., & Cullheim, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0079395 · Cited by 47
Sandau, U. S., Mungenast, A. E., Alderman, Z., Sardi, S. P., Fogel, A. I., Taylor, B., Parent, A., Biederer, T., Corfas, G., & Ojeda, S. R. (2011) · Endocrinology · doi:10.1210/en.2010-1435 · Cited by 44
The Gliotransmitter d-Serine Promotes Synapse Maturation and Axonal Stabilization In Vivo
Horn, M. R. V., Strasser, A., Miraucourt, L. S., Pollegioni, L., & Ruthazer, E. S. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3158-16.2017 · Cited by 43
Confocal Microscopy and Computer‐assisted Image Reconstruction of Astrocytes in the Mammalian Retina
Rungger‐Brändle, E., Messerli, J. M., Niemeyer, G., & Eppenberger, H. M. (1993) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1993.tb00963.x · Cited by 38
Dystroglycan: a multifunctional adaptor protein
Higginson, J. R., & Winder, S. J. (2005) · Biochemical Society Transactions · doi:10.1042/bst20051254 · Cited by 30
Voluntary Exercise Induces Astrocytic Structural Plasticity in the Globus Pallidus
Tatsumi, K., Okuda, H., Takemura, S., Tanaka, T., Isonishi, A., Shinjo, T., Terada, Y., & Wanaka, A. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00165 · Cited by 30
Lapsyn controls branch extension and positioning of astrocyte-like glia in the Drosophila optic lobe
Richier, B., de Miguel, C., Mackensen, S., & Salecker, I. (2017) · Nature Communications · doi:10.1038/s41467-017-00384-z · Cited by 30
Eom, T. Y., Stanco, A., Weimer, J. M., Stabingas, K., Sibrack, E., Ghukasyan, V., Cheng, J., & Anton, E. S. (2011) · Nature Communications · doi:10.1038/ncomms1460 · Cited by 29
Signalling Pathways Controlling Cellular Actin Organization
Steffen, A., Stradal, T. E. B., & Rottner, K. (2016) · Handbook of experimental pharmacology · doi:10.1007/164_2016_35 · Cited by 26
Burgos, M., Calvo, S., Molina, F., Vaquero, C. F., Samarel, A. M., Llopis, J., & Tranque, P. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05364.x · Cited by 25
Profilin Isoforms Modulate Astrocytic Morphology and the Motility of Astrocytic Processes
Schweinhuber, S. K., Meßerschmidt, T., Hänsch, R., Körte, M., & Rothkegel, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0117244 · Cited by 22
Probing nano‐organization of astroglia with multi‐color super‐resolution microscopy
Heller, J. P., Michaluk, P., Sugao, K., & Rusakov, D. A. (2017) · Journal of Neuroscience Research · doi:10.1002/jnr.24026 · Cited by 19
Woo, J., Im, S.-K., Chun, H., Jung, S.-Y., Oh, S., Choi, N., Lee, C. J., & Hur, E. (2017) · Experimental Neurobiology · doi:10.5607/en.2017.26.3.158 · Cited by 17
Culturing In Vivo-like Murine Astrocytes Using the Fast, Simple, and Inexpensive AWESAM Protocol
Wolfes, A. C., & Dean, C. (2018) · Journal of Visualized Experiments · doi:10.3791/56092 · Cited by 17
The problem of astrocyte identity
Kimelberg, H. K. (2004) · Neurochemistry International · doi:10.1016/s0197-0186(03)00286-9 · Cited by 16
Cardiac Muscle Activation Blunted by a Mutation to the Regulatory Component, Troponin T
Kobayashi, M., Debold, E. P., Turner, M. A., & Kobayashi, T. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.494096 · Cited by 11
Winkler, U., Hirrlinger, P., Sestu, M., Wilhelm, F., Besser, S., Zemljic-Harpf, A. E., Ross, R., Bornschein, G., Krügel, U., Ziegler, W., et al. (2013) · Glia · doi:10.1002/glia.22495 · Cited by 3
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- Ramón y Cajal, 1913, Un nuevo proceder para la impregnación de la neuroglía, Bol. Soc. Esp. Bio., 2, 104
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Questions and (some) answers on reactive astrocytes
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Fatigue, Sleep, and Autoimmune and Related Disorders
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Metadata
- Authors
- Schiweck, J., Eickholt, B. J., & Murk, K.
- Affiliations
- Charité – Universitätsmedizin Berlin (DE)
- Corresponding author
- Eickholt, Britta J.
- Murk, Kai
- Venue
- Frontiers in Cellular Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2018-08-21
- Volume
- 12
- Pages
- 261-261
- ISSN
- 1662-5102 (ISSN-L)
- PMC
- PMC6111612
- OpenAlex
- W2888094777
- Cited by
- 223
- References
- 169
- Citations by year
- 2026: 14 · 2025: 28 · 2024: 25 · 2023: 23 · 2022: 38 · 2021: 44 · 2020: 33 · 2019: 18
- FWCI
- 10.82
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Frontiers in Cellular Neuroscience (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Refubium (Universitätsbibliothek der Freien Universität Berlin) (submittedVersion, cc-by)
- Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver (cc-by)
- Funders
- Deutsche Forschungsgemeinschaft (SFB958, TRR168, 285933818)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- astrocytes, astrocyte morphology, synaptogenesis, synaptic plasticity, neural transmission, astrocyte development, traumatic brain injury, neurodegenerative diseases, blood-brain barrier, cytoskeleton, glial cells
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