International Journal of Molecular Sciences

GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

Oh, D. Y., Talukdar, S., Bae, E. J., Imamura, T., Morinaga, H., Fan, W., Li, P., Lu, W. J., Watkins, S. M., & Olefsky, J. M. (2010) · Cell · doi:10.1016/j.cell.2010.07.041 · Cited by 2,428

Functions of RANKL/RANK/OPG in bone modeling and remodeling

Boyce, B. F., & Xing, L. (2008) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2008.03.018 · Cited by 1,844

Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases

Callaway, D. A., & Jiang, J. X. (2015) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-015-0656-4 · Cited by 393

Athletes and Supplements: Prevalence and Perspectives

Garthe, I., & Maughan, R. J. (2018) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.2017-0429 · Cited by 383

Trials and Tribulations of MicroRNA Therapeutics

Seyhan, A. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031469 · Cited by 381

Genomic atlas of the proteome from brain, CSF and plasma prioritizes proteins implicated in neurological disorders

Yang, C., Farias, F. H. G., Ibanez, L., Suhy, A., Sadler, B., Fernandez, M. V., Wang, F., Bradley, J. L., Eiffert, B., Bahena, J. A., et al. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00886-6 · Cited by 290

Physiological and molecular mechanisms of metal accumulation in hyperaccumulator plants

Sytar, O., Ghosh, S., Malinska, H., Zivcak, M., & Brestic, M. (2020) · Physiologia Plantarum · doi:10.1111/ppl.13285 · Cited by 192

Alzheimer’s Disease: Exploring the Landscape of Cognitive Decline

Tenchov, R., Sasso, J. M., & Zhou, Q. A. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.4c00339 · Cited by 170

The Tumor Microenvironment in Tumorigenesis and Therapy Resistance Revisited

Dzobo, K., Senthebane, D. A., & Dandara, C. (2023) · Cancers · doi:10.3390/cancers15020376 · Cited by 146

Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease

Fitz, N. F., Nam, K. N., Wolfe, C. M., Letronne, F., Playso, B. E., Iordanova, B. E., Kozai, T. D. Y., Biedrzycki, R. J., Kagan, V. E., Tyurina, Y. Y., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23762-0 · Cited by 129

Persistence of plastic debris and its colonization by bacterial communities after two decades on the abyssal seafloor

Krause, S., Molari, M., Gorb, E. V., Gorb, S. N., Kossel, E., & Haeckel, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-66361-7 · Cited by 125

Abiotic Stress Responses in Plants: Unraveling the Complexity of Genes and Networks to Survive

Sofia, A., de Almeida, A. M., da Silva, A. B., da Silva, J. M., Paula, A., Santos, D., Fevereiro, P., & Sousa Araujo, S. D. (2013) · Abiotic Stress - Plant Responses and Applications in Agriculture · doi:10.5772/52779 · Cited by 106

Coloring Molecules with Explainable Artificial Intelligence for Preclinical Relevance Assessment

Jiménez-Luna, J., Skalic, M., Weskamp, N., & Schneider, G. (2021) · Journal of Chemical Information and Modeling · doi:10.1021/acs.jcim.0c01344 · Cited by 96

Naturally-aged microglia exhibit phagocytic dysfunction accompanied by gene expression changes reflective of underlying neurologic disease

Thomas, A. L., Lehn, M. A., Janssen, E. M., Hildeman, D. A., & Chougnet, C. A. (2022) · Scientific Reports · doi:10.1038/s41598-022-21920-y · Cited by 94

Performance comparison of deep learning autoencoders for cancer subtype detection using multi-omics data

Franco, E. F., Rana, P., Cruz, A., Calderón, V. V., Azevedo, V., Ramos, R. T. J., & Ghosh, P. (2021) · Cancers · doi:10.3390/cancers13092013 · Cited by 92

GSK3 and p53 - is there a link in Alzheimer's disease?

Proctor, C. J., & Gray, D. A. (2010) · Molecular Neurodegeneration · doi:10.1186/1750-1326-5-7 · Cited by 80

Insights into decontamination of soils by phytoremediation: A detailed account on heavy metal toxicity and mitigation strategies

Rai, G. K., Bhat, B. A., Mushtaq, M., Tariq, L., Rai, P. K., Basu, U., Dar, A. A., Islam, S. T., Dar, T. U. H., & Bhat, J. A. (2021) · Physiologia Plantarum · doi:10.1111/ppl.13433 · Cited by 80

Current perspectives on the cellular and molecular features of epigenetic ageing

Raj, K., & Horvath, S. (2020) · Experimental Biology and Medicine · doi:10.1177/1535370220918329 · Cited by 77

Lactobacillus plantarum-derived extracellular vesicles protect against ischemic brain injury via the microRNA-101a-3p/c-Fos/TGF-β axis

Yang, Z., Gao, Z., Yang, Z., Zhang, Y., Chen, H., Yang, X., Fang, X., Zhu, Y., Zhang, J., Ouyang, F., et al. (2022) · Pharmacological Research · doi:10.1016/j.phrs.2022.106332 · Cited by 75

The influence of age, sex, and exercise on autophagy, mitophagy, and lysosome biogenesis in skeletal muscle

Triolo, M., Oliveira, A. N., Kumari, R., & Hood, D. A. (2022) · Skeletal Muscle · doi:10.1186/s13395-022-00296-7 · Cited by 75

Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors

Torok, S., Rezeli, M., Kelemen, O., Vegvari, A., Watanabe, K., Sugihara, Y., Tisza, A., Marton, T., Kovacs, I., Tovari, J., et al. (2017) · Theranostics · doi:10.7150/thno.16767 · Cited by 70

Stacking for future: pyramiding genes to improve drought and salinity tolerance in rice

Shailani, A., Joshi, R., Singla‐Pareek, S. L., & Pareek, A. (2021) · Physiologia Plantarum · doi:10.1111/ppl.13270 · Cited by 65

Neural functions of hypothalamic oxytocin and its regulation

Wang, P., Wang, S. C., Liu, X., Jia, S., Wang, X., Li, T., Yu, J., Parpura, V., & Wang, Y.-F. (2022) · ASN Neuro · doi:10.1177/17590914221100706 · Cited by 59

A cell-autonomous role for border-associated macrophages in ApoE4 neurovascular dysfunction and susceptibility to white matter injury

Anfray, A., Schaeffer, S., Hattori, Y., Santisteban, M. M., Casey, N., Wang, G., Strickland, M., Zhou, P., Holtzman, D. M., Anrather, J., et al. (2024) · Nature Neuroscience · doi:10.1038/s41593-024-01757-6 · Cited by 53

GLP-1 receptor agonist-based therapies and cardiovascular risk: a review of mechanisms

Mullur, N., Morissette, A., Morrow, N. M., & Mulvihill, E. E. (2024) · Journal of Endocrinology · doi:10.1530/joe-24-0046 · Cited by 51

RISING STARS: androgens and immune cell function

Ainslie, R. J., Simitsidellis, I., Kirkwood, P. M., & Gibson, D. A. (2024) · Journal of Endocrinology · doi:10.1530/joe-23-0398 · Cited by 48

Towards a comprehensive definition of the human fascial system

Stecco, C., Pratt, R., Nemetz, L. D., Schleip, R., Stecco, A., & Theise, N. D. (2025) · Journal of Anatomy · doi:10.1111/joa.14212 · Cited by 53

Mitochondrial Metabolism: A New Dimension of Personalized Oncology

Behnam, B., & Taghizadeh-Hesary, F. (2023) · Cancers · doi:10.3390/cancers15164058 · Cited by 44

Levilactobacillus brevis from carnivores can ameliorate hypercholesterolemia: In vitro and in vivo mechanistic evidence

Munir, A., Javed, G. A., Javed, S., & Arshad, N. (2022) · Journal of Applied Microbiology · doi:10.1111/jam.15678 · Cited by 40

Assessment of safety and efficacy of intra-articular injection of stromal vascular fraction for the treatment of knee osteoarthritis—a systematic review

Shanmugasundaram, S., Vaish, A., Chavada, V., Murrell, W. D., & Vaishya, R. (2021) · International Orthopaedics · doi:10.1007/s00264-020-04926-x · Cited by 39

The emerging role of glucagon-like peptide 1 in binge eating

Balantekin, K. N., Kretz, M. J., & Mietlicki-Baase, E. G. (2024) · Journal of Endocrinology · doi:10.1530/joe-23-0405 · Cited by 38

hMSCs-derived exosome circCDK13 inhibits liver fibrosis by regulating the expression of MFGE8 through miR-17-5p/KAT2B

Ma, J., Li, Y., Chen, M., Wang, W., Zhao, Q., He, B., Zhang, M., & Jiang, Y. (2023) · Cell Biology and Toxicology · doi:10.1007/s10565-022-09714-4 · Cited by 37

Population decline: where demography, social science, and biology intersect

Aitken, R. J. (2024) · Reproduction · doi:10.1530/rep-24-0070 · Cited by 33

The Synaptic Vesicle Protein 2A Interacts With Key Pathogenic Factors in Alzheimer’s Disease: Implications for Treatment

Kong, Y., Huang, L., Li, W., Liu, X., Zhou, Y., Liu, C., Zhang, S., Xie, F., Zhang, Z., Jiang, D., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.609908 · Cited by 29

Effects of strong physical exercise on blood glutamate and its metabolite 2-ketoglutarate levels in healthy volunteers

Leibowitz, A., Klin, Y., Gruenbaum, B., Gruenbaum, S., Kuts, R., Dubilet, M., Ohayon, S., Boyko, M., Sheiner, E., Shapira, Y., et al. (2012) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2012-1910 · Cited by 28

A pan-cancer dye for solid-tumour screening, resection and wound monitoring via short-wave and near-infrared fluorescence imaging

Mc Larney, B. E., Sonay, A. Y., Apfelbaum, E., Mostafa, N., Monette, S., Goerzen, D., Aguirre, N., Exner, R. M., Habjan, C., Isaac, E., et al. (2024) · Nature Biomedical Engineering · doi:10.1038/s41551-024-01248-w · Cited by 28

Genome-wide transcriptome profiling of human trabecular meshwork cells treated with TGF-β2

Callaghan, B., Lester, K., Lane, B., Fan, X., Goljanek-Whysall, K., Simpson, D. A., Sheridan, C., & Willoughby, C. E. (2022) · Scientific Reports · doi:10.1038/s41598-022-13573-8 · Cited by 27

In Silico Characterization and Expression Profiles of Heat Shock Transcription Factors (HSFs) in Maize (Zea mays L.)

Haider, S., Rehman, S., Ahmad, Y., Raza, A., Tabassum, J., Javed, T., Osman, H. S., & Mahmood, T. (2021) · Agronomy · doi:10.3390/agronomy11112335 · Cited by 26

Novel Antimicrobial Peptides Designed Using a Recurrent Neural Network Reduce Mortality in Experimental Sepsis

Bolatchiev, A., Baturin, V., Shchetinin, E., & Bolatchieva, E. (2022) · Antibiotics · doi:10.3390/antibiotics11030411 · Cited by 26

Bacterial catabolism of s-triazine herbicides: biochemistry, evolution and application

(2020) · Advances in Microbial Physiology · doi:10.1016/bs.ampbs.2020.01.004 · Cited by 23

Knockdown of β‐conglycinin α′ and α subunits alters seed protein composition and improves salt tolerance in soybean

Yang, R., Ma, Y., Yang, Z., Pu, Y., Liu, M., Du, J., Xu, Z., Xu, Z., Zhang, S., Zhang, H., et al. (2024) · The Plant Journal · doi:10.1111/tpj.17062 · Cited by 23

How Can ChatGPT Benefit Pharmacy: A Case Report on Review Writing

Zhu, Y., Han, D., Chen, S., Zeng, F., & Wang, C. (2023) · doi:10.20944/preprints202302.0324.v1 · Cited by 21

Arabidopsis calmodulin‐like proteins CML13 and CML14 interact with proteins that have IQ domains

Teresinski, H. J., Hau, B., Symonds, K., Kilburn, R., Munro, K. A., Doner, N. M., Mullen, R., Li, V. H., & Snedden, W. A. (2023) · Plant, Cell & Environment · doi:10.1111/pce.14616 · Cited by 21

Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates

Papadopoulos, N., Suelves, N., Perrin, F., Vadukul, D. M., Vrancx, C., Constantinescu, S. N., & Kienlen-Campard, P. (2022) · Biomedicines · doi:10.3390/biomedicines10112753 · Cited by 20

Surrogate Based Genetic Algorithm Method for Efficient Identification of Low-Energy Peptide Structures

Villard, J., Kılıç, M., & Rothlisberger, U. (2023) · Journal of Chemical Theory and Computation · doi:10.1021/acs.jctc.2c01078 · Cited by 19

Idiopathic Pulmonary Fibrosis: Where do We Stand and How Far to Go?

Singh, V., Ulasov, I., Gupta, S., Singh, A., Roy, V. K., & Kharwar, R. K. (2024) · Discovery Medicine · doi:10.24976/discov.med.202436180.3 · Cited by 17

The Impact of Pollution and Climate Change on Skin Health: Mechanisms, Protective Strategies, and Future Directions

Haykal, D., Lim, H. W., Calzavara-Pinton, P., Fluhr, J., Cartier, H., & Berardesca, E. (2025) · JAAD Reviews · doi:10.1016/j.jdrv.2025.05.001 · Cited by 16

Chitosan inhibits the rehabilitation of damaged microbes induced by photodynamic inactivation.

Lin, C.-H., Chien, H.-F., Lin, M.-H., Chen, C.-P., Shen, M., & Chen, C.-T. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092598 · Cited by 16

Whole-Genome Alignment: Methods, Challenges, and Future Directions

Saada, B., Zhang, T., Siga, E., Zhang, J., & Magalhães Muniz, M. M. (2024) · Applied Sciences · doi:10.3390/app14114837 · Cited by 15

Effects of Mars global simulant (MGS-1) on growth and physiology of sweet potato: a space model plant

Chinnannan, K., Somagattu, P., Yammanuru, H., Nimmakayala, P., Chakrabarti, M., & Reddy, U. K. (2023) · Plants · doi:10.3390/plants13010055 · Cited by 15

Proteomic characterization of pilot scale hot-water extracts from the industrial carrageenan red seaweed Eucheuma denticulatum

Gregersen, S., Pertseva, M., Marcatili, P., Holdt, S. L., Jacobsen, C., García-Moreno, P. J., Hansen, E. B., & Overgaard, M. T. (2022) · Algal Research · doi:10.1016/j.algal.2021.102619 · Cited by 15

The Role of a Lung Vascular Endothelium Enriched Gene TMEM100

Pan, J., Liu, B., & Dai, Z. (2023) · Biomedicines · doi:10.3390/biomedicines11030937 · Cited by 14

The immune interactions of gut glycans and microbiota in health and disease

(2024) · doi:10.1111/mmi.15267 · Cited by 14

miR-23b-3p regulates human endometrial epithelial cell adhesion implying a role in implantation

Barton, S., Zhou, W., Santos, L. L., Menkhorst, E., Yang, G., Tinn Teh, W., Ang, C., Lucky, T., & Dimitriadis, E. (2023) · Reproduction · doi:10.1530/rep-22-0338 · Cited by 11

Stem Cell-Based Strategies: The Future Direction of Bioartificial Liver Development

Feng, L., Wang, Y., Fu, Y., Li, T., & He, G. (2024) · Stem Cell Reviews and Reports · doi:10.1007/s12015-023-10672-5 · Cited by 9

Nrf2 signaling pathway: focus on oxidative stress in osteoporosis

Gu, H.-Y., Liu, N., Lin, F.-X., & Yin, J. (2025) · Osteoporosis International · doi:10.1007/s00198-025-07592-0 · Cited by 10

Integrating Phenotypic and Chemoproteomic Approaches to Identify Covalent Targets of Dietary Electrophiles in Platelets

(2024) · doi:10.1021/acscentsci.3c00822 · Cited by 9

Cosolvent and Dynamic Effects in Binding Pocket Search by Docking Simulations

(2021) · doi:10.1021/acs.jcim.1c00924 · Cited by 9

Dynamic changes in mRNA nucleocytoplasmic localization in the nitrate response of Arabidopsis roots

(2024) · doi:10.1111/pce.15018 · Cited by 9

An artificial neural network model to predict structure-based protein–protein free energy of binding from Rosetta-calculated properties

Ferraz, M. V. F., Neto, J. C. S., Lins, R. D., & Teixeira, E. S. (2023) · Physical Chemistry Chemical Physics · doi:10.1039/d2cp05644e · Cited by 9

HIF is not essential for suppression of experimental tumor growth by mTOR inhibition

Knaup, K. X., Guenther, R., Stoeckert, J., Monti, J. M., Eckardt, K.-U., & Wiesener, M. S. (2017) · Journal of Cancer · doi:10.7150/jca.16486 · Cited by 7

Borrelia burgdorferi PlzA is a cyclic‐di‐GMP dependent DNA and RNA binding protein

Jusufovic, N., Krusenstjerna, A. C., Savage, C. R., Saylor, T. C., Brissette, C. A., Zückert, W. R., Schlax, P. J., Motaleb, M. A., & Stevenson, B. (2024) · Molecular Microbiology · doi:10.1111/mmi.15254 · Cited by 7

Exploring the potential of crossbreeding to enhance black soldier fly (Hermetia illucens) production

Meyermans, R., Broeckx, L., Mondelaers, J., Gorssen, W., Frooninckx, L., Janssens, S., Van Miert, S., & Buys, N. (2025) · Journal of Insects as Food and Feed · doi:10.1163/23524588-00001391 · Cited by 6

A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues

(2021) · doi:10.21203/rs.3.rs-1034608/v1 · Cited by 6

BugBook: Life cycle, reproduction, and morphofunctional characterisation of the gut, fat body, and haemocytes in the black soldier fly

Bruno, D., Manas, F., Bonelli, M., Gold, M., Marzari, M., Roma, D., Valoroso, M. C., Montali, A., Guillaume, J. B., Rebora, M., et al. (2025) · Journal of Insects as Food and Feed · doi:10.1163/23524588-20250002 · Cited by 6

Molecular basis of one‐step methyl anthranilate biosynthesis in grapes, sweet orange, and maize

(2024) · doi:10.1111/tpj.16922 · Cited by 5

The causal association between circulating metabolites and Alzheimer’s disease: A systematic review and meta-analysis of Mendelian randomization studies

Wu, Y., Chen, F., Zhang, T., Miao, M., Zhang, M., Zhang, J., & Chang, E. (2025) · Metabolomics · doi:10.1007/s11306-025-02242-2 · Cited by 2

In Vitro Quorum Quenching Activity of Eleusine indica Crude Ethanolic Extract against Pseudomonas aeruginosa and Serratia marcescens

(2021) · Acta Medica Philippina · doi:10.47895/amp.vi0.3262 · Cited by 1