Role of Intestinal Microbiota in the Bioavailability and Physiological Functions of Dietary Polyphenols

An obesity-associated gut microbiome with increased capacity for energy harvest

Turnbaugh, P. J., Ley, R. E., Mahowald, M. A., Magrini, V., Mardis, E. R., & Gordon, J. I. (2006) · Nature · doi:10.1038/nature05414 · Cited by 12,444

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

Koh, A., De Vadder, F., Kovatcheva-Datchary, P., & Bäckhed, F. (2016) · Cell · doi:10.1016/j.cell.2016.05.041 · Cited by 7,070

Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

Cryan, J. F., & Dinan, T. G. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3346 · Cited by 4,572

Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

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Dietary Intake and Bioavailability of Polyphenols

Scalbert, A., & Williamson, G. (2000) · The Journal of Nutrition · doi:10.1093/jn/130.8.2073s · Cited by 3,658

Postnatal microbial colonization programs the hypothalamic–pituitary–adrenal system for stress response in mice

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Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases

Del Rio, D., Rodriguez-Mateos, A., Spencer, J. P. E., Tognolini, M., Borges, G., & Crozier, A. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4581 · Cited by 2,601

A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

Plovier, H., Everard, A., Druart, C., Depommier, C., Van Hul, M., Geurts, L., Chilloux, J., Ottman, N., Duparc, T., Lichtenstein, L., et al. (2017) · Nature Medicine · doi:10.1038/nm.4236 · Cited by 2,204

Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium

Derrien, M., Vaughan, E. E., Plugge, C. M., & de Vos, W. M. (2004) · International Journal of Systematic and Evolutionary Microbiology · doi:10.1099/ijs.0.02873-0 · Cited by 2,094

Benefits of polyphenols on gut microbiota and implications in human health

Cardona, F., Andrés‐Lacueva, C., Tulipani, S., Tinahones, F. J., & Queipo‐Ortuño, M. I. (2013) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2013.05.001 · Cited by 1,615

Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies

Williamson, G., & Manach, C. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.243s · Cited by 1,340

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice

Anhê, F. F., Roy, D., Pilon, G., Dudonné, S., Matamoros, S., Varin, T. V., Garofalo, C., Moine, Q., Desjardins, Y., Levy, E., et al. (2015) · Gut · doi:10.1136/gutjnl-2014-307142 · Cited by 1,137

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

Ryu, D., Mouchiroud, L., Andreux, P. A., Katsyuba, E., Moullan, N., Nicolet-dit-Félix, A. A., Williams, E. G., Jha, P., Lo Sasso, G., Huzard, D., et al. (2016) · Nature Medicine · doi:10.1038/nm.4132 · Cited by 1,105

The gut microbiota at the intersection of diet and human health

Gentile, C. L., & Weir, T. L. (2018) · Science · doi:10.1126/science.aau5812 · Cited by 1,049

Gut microbes and the brain: paradigm shift in neuroscience

Mayer, E. A., Knight, R., Mazmanian, S. K., Cryan, J. F., & Tillisch, K. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.3299-14.2014 · Cited by 1,033

Concentrations of Proanthocyanidins in Common Foods and Estimations of Normal Consumption

Kelm, M. A., Hammerstone, J. F., Beecher, G. R., Holden, J., Haytowitz, D. B., Gebhardt, S. E., Gu, L., & Prior, R. L. (2004) · Journal of Nutrition · doi:10.1093/jn/134.3.613 · Cited by 941

Hydrogen peroxide sensing, signaling and regulation of transcription factors

Marinho, H. S., Real, C., Cyrne, L., Soares, H., & Antunes, F. (2014) · Redox Biology · doi:10.1016/j.redox.2014.02.006 · Cited by 872

Bioavailability of Dietary Polyphenols and Gut Microbiota Metabolism: Antimicrobial Properties

Marín, L., Miguélez, E. M., Villar, C. J., & Lombó, F. (2015) · BioMed Research International · doi:10.1155/2015/905215 · Cited by 802

Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice

Schneeberger, M., Everard, A., Gómez-Valadés, A. G., Matamoros, S., Ramírez, S., Delzenne, N. M., Gomis, R., Claret, M., & Cani, P. D. (2015) · Scientific Reports · doi:10.1038/srep16643 · Cited by 798

Survival and therapeutic potential of probiotic organisms with reference to Lactobacillus acidophilus and Bifidobacterium spp.

Kailasapathy, K., & Chin, J. J.-C. (2000) · Immunology and Cell Biology · doi:10.1046/j.1440-1711.2000.00886.x · Cited by 792

Resveratrol Attenuates Trimethylamine- N -Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota

Chen, M.-L., Yi, L., Zhang, Y., Zhou, X., Ran, L., Yang, J., Zhu, J.-D., Zhang, Q.-Y., & Mi, M.-T. (2016) · mBio · doi:10.1128/mbio.02210-15 · Cited by 754 · cited 1×

Metformin Is Associated With Higher Relative Abundance of Mucin-Degrading Akkermansia muciniphila and Several Short-Chain Fatty Acid–Producing Microbiota in the Gut

de la Cuesta-Zuluaga, J., Mueller, N. T., Corrales-Agudelo, V., Velásquez-Mejía, E. P., Carmona, J. A., Abad, J. M., & Escobar, J. S. (2017) · Diabetes Care · doi:10.2337/dc16-1324 · Cited by 704

Proanthocyanidins and hydrolysable tannins: occurrence, dietary intake and pharmacological effects

Smeriglio, A., Barreca, D., Bellocco, E., & Trombetta, D. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13630 · Cited by 692

Dietary Polyphenols Promote Growth of the Gut Bacterium Akkermansia muciniphila and Attenuate High-Fat Diet–Induced Metabolic Syndrome

Roopchand, D. E., Carmody, R. N., Kuhn, P., Moskal, K., Rojas-Silva, P., Turnbaugh, P. J., & Raskin, I. (2015) · Diabetes · doi:10.2337/db14-1916 · Cited by 678

Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers

Queipo-Ortuño, M. I., Boto-Ordóñez, M., Murri, M., Gomez-Zumaquero, J. M., Clemente-Postigo, M., Estruch, R., Cardona Diaz, F., Andrés-Lacueva, C., & Tinahones, F. J. (2012) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.027847 · Cited by 671

Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review

Duda-Chodak, A., Tarko, T., Satora, P., & Sroka, P. (2015) · European Journal of Nutrition · doi:10.1007/s00394-015-0852-y · Cited by 599

Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a 13C-tracer study

Czank, C., Cassidy, A., Zhang, Q., Morrison, D. J., Preston, T., Kroon, P. A., Botting, N. P., & Kay, C. D. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.049247 · Cited by 598

Antimicrobial activity of phenolic acids against commensal, probiotic and pathogenic bacteria

Cueva, C., Moreno-Arribas, M. V., Martín‐Álvarez, P. J., Bills, G. F., Vicente, M. F., Basilio, Á., Rivas, C. L., Requena, T., Rodríguez, J. M., & Bartolomé, B. (2010) · Research in Microbiology · doi:10.1016/j.resmic.2010.04.006 · Cited by 579

Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine.

Ireson, C. R., Jones, D. J. L., Orr, S., Coughtrie, M. W. H., Boocock, D. J., Williams, M. L., Farmer, P. B., Steward, W. P., & Gescher, A. J. (2002) · PubMed · Cited by 561

Metabolic fate of polyphenols in the human superorganism

van Duynhoven, J., Vaughan, E. E., Jacobs, D. M., A. Kemperman, R., van Velzen, E. J. J., Gross, G., Roger, L. C., Possemiers, S., Smilde, A. K., Doré, J., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000098107 · Cited by 540

Antioxidative flavonoid quercetin: implication of its intestinal absorption and metabolism.

Murota, K., & Terao, J. (2003) · Archives of Biochemistry and Biophysics · doi:10.1016/s0003-9861(03)00284-4 · Cited by 531

Pharmacokinetics of quercetin from quercetin aglycone and rutin in healthy volunteers

Erlund, I., Kosonen, T., Alfthan, G., Mäenpää, J., Perttunen, K., Kenraali, J., Parantainen, J., & Aro, A. (2000) · European Journal of Clinical Pharmacology · doi:10.1007/s002280000197 · Cited by 524

The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids

Cassidy, A., & Minihane, A. M. (2016) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.136051 · Cited by 522

Colonic metabolism of dietary polyphenols: influence of structure on microbial fermentation products

Rechner, A. R., Smith, M. A., Kuhnle, G., Gibson, G. R., Debnam, E. S., Srai, S. K., Moore, K. P., & Rice-Evans, C. A. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2003.09.022 · Cited by 512

Protocatechuic Acid Is the Major Human Metabolite of Cyanidin-Glucosides3

Vitaglione, P., Donnarumma, G., Napolitano, A., Galvano, F., Gallo, A., Scalfi, L., & Fogliano, V. (2007) · Journal of Nutrition · doi:10.1093/jn/137.9.2043 · Cited by 504

Pomegranate Juice Ellagitannin Metabolites Are Present in Human Plasma and Some Persist in Urine for Up to 48 Hours

Seeram, N. P., Henning, S. M., Zhang, Y., Suchard, M. A., Li, Z., & Heber, D. (2006) · Journal of Nutrition · doi:10.1093/jn/136.10.2481 · Cited by 477

Chlorogenic Acid, Quercetin-3-Rutinoside and Black Tea Phenols Are Extensively Metabolized in Humans

Olthof, M. R., Hollman, P. C. H., Buijsman, M. N. C. P., van Amelsvoort, J. M. M., & Katan, M. B. (2003) · The Journal of Nutrition · doi:10.1093/jn/133.6.1806 · Cited by 468 · cited 1×

In vitro metabolism of anthocyanins by human gut microflora

Aura, A., Martin-Lopez, P., O’Leary, K. A., Williamson, G., Oksman‐Caldentey, K., Poutanen, K. S., & Santos‐Buelga, C. (2004) · European Journal of Nutrition · doi:10.1007/s00394-004-0502-2 · Cited by 461

Bioavailability of ellagic acid in human plasma after consumption of ellagitannins from pomegranate (Punica granatum L.) juice

Seeram, N. P., Lee, R., & Heber, D. (2004) · Clinica Chimica Acta · doi:10.1016/j.cccn.2004.04.029 · Cited by 454

Metabolism of Antioxidant and Chemopreventive Ellagitannins from Strawberries, Raspberries, Walnuts, and Oak-Aged Wine in Humans: Identification of Biomarkers and Individual Variability

Cerdá, B., Tomás-Barberán, F. A., & Espı́n, J. C. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf049144d · Cited by 448

Berry phenolics selectively inhibit the growth of intestinal pathogens

Puupponen‐Pimiä, R., Nohynek, L. J., Hartmann-Schmidlin, S., Kähkönen, M., Heinonen, M., Riihinen, K., & Oksman‐Caldentey, K. (2005) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2005.02547.x · Cited by 420

Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status

Tomás-Barberán, F. A., García-Villalba, R., González-Sarrías, A., Selma, M. V., & Espín, J. C. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf5024615 · Cited by 419

Diet-Derived Phenols in Plasma and Tissues and their Implications for Health

Clifford, M. N. (2004) · Planta Medica · doi:10.1055/s-2004-835835 · Cited by 410

The Biological Relevance of Direct Antioxidant Effects of Polyphenols for Cardiovascular Health in Humans Is Not Established1–4

Hollman, P. C. H., Cassidy, A., Comte, B., Heinonen, M., Richelle, M., Richling, E., Serafini, M., Scalbert, A., Sies, H., & Vidry, S. (2011) · The Journal of Nutrition · doi:10.3945/jn.110.131490 · Cited by 406

In vivo and in vitro metabolism of trans-resveratrol by human gut microbiota

Bode, L. M., Bunzel, D., Huch, M., Cho, G., Ruhland, D., Bunzel, M., Bub, A., Franz, C. M. A. P., & Kulling, S. E. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.049379 · Cited by 404

Impact of Polyphenols and Polyphenol-Rich Dietary Sources on Gut Microbiota Composition

Etxeberría, U., Fernández‐Quintela, A., Milagro, F. I., Aguirre, L., Martínez, J. A., & Portillo, M. P. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf402506c · Cited by 394

Dietary proanthocyanidins: Occurrence, dietary intake, bioavailability, and protection against cardiovascular disease

Rasmussen, S. E., Frederiksen, H. W., Krogholm, K. S., & Bredsdorff, L. (2005) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200400082 · Cited by 373

Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity

Qiao, Y., Sun, J., Xia, S., Tang, X., Shi, Y., & Le, G. (2014) · Food & Function · doi:10.1039/c3fo60630a · Cited by 367

Effect of a Low Dose of Dietary Resveratrol on Colon Microbiota, Inflammation and Tissue Damage in a DSS-Induced Colitis Rat Model

Larrosa, M., Yañéz-Gascón, M. J., Selma, M. V., González-Sarrías, A., Toti, S., Cerón, J. J., Tomás-Barberán, F., Dolara, P., & Espín, J. C. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf803638d · Cited by 365

The Metabolism and Excretion of Curcumin (1,7-Bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione) in the Rat

Holder, G. M., Plummer, J. L., & Ryan, A. J. (1978) · Xenobiotica · doi:10.3109/00498257809069589 · Cited by 361

Absorption, Bioavailability, and Metabolism of Flavonoids

Hollman, P. C. H. (2004) · Pharmaceutical Biology · doi:10.3109/13880200490893492 · Cited by 361

Metabolism of dietary procyanidins in rats

Gonthier, M., Donovan, J. L., Texier, O., Felgines, C., Rémésy, C., & Scalbert, A. (2003) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(03)00394-0 · Cited by 345

Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC–EURGAST)

Gonzalez, C. A., Pera, G., Agudo, A., Bueno-de-Mesquita, H. B., Ceroti, M., Boeing, H., Schulz, M., Giudice, G. D., Plebani, M., Carneiro, F., et al. (2005) · International Journal of Cancer · doi:10.1002/ijc.21678 · Cited by 342

Strawberry Anthocyanins Are Recovered in Urine as Glucuro- and Sulfoconjugates in Humans

Felgines, C., Talavéra, S., Texier, O., Lamaison, J., Gonthier, M., Scalbert, A., & Rémésy, C. (2003) · Journal of Nutrition · doi:10.1093/jn/133.5.1296 · Cited by 337

Quercetin and related polyphenols: new insights and implications for their bioactivity and bioavailability

Kawabata, K., Mukai, R., & Ishisaka, A. (2015) · Food & Function · doi:10.1039/c4fo01178c · Cited by 336

Phenols, Polyphenols and Tannins: An Overview

Crozier, A., Jaganath, I. B., & Clifford, M. N. (2006) · Wiley eBooks · doi:10.1002/9780470988558.ch1 · Cited by 333

Cocoa procyanidins are stable during gastric transit in humans,,

Rios, L. Y., Bennett, R. N., Lazarus, S. A., Rémésy, C., Scalbert, A., & Williamson, G. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.5.1106 · Cited by 327

Gut Microbiota Metabolism of Anthocyanin Promotes Reverse Cholesterol Transport in Mice Via Repressing miRNA-10b

Wang, D., Xia, M., Xiao, Y., Li, D., Wang, L., Xu, Y., Jin, T., & Ling, W. (2012) · Circulation Research · doi:10.1161/circresaha.112.266502 · Cited by 319

Hypoxia and gastrointestinal disease

Taylor, C. T., & Colgan, S. P. (2007) · Journal of Molecular Medicine · doi:10.1007/s00109-007-0277-z · Cited by 313

Lactic acid bacteria secrete metabolites retaining anti-inflammatory properties after intestinal transport

Ménard, S., Candalh, C., Bambou, J. C., Terpend, K., Cerf–Bensussan, N., & Heyman, M. (2004) · Gut · doi:10.1136/gut.2003.026252 · Cited by 309

Dietary polyphenols: Structures, bioavailability and protective effects against atherosclerosis

Santhakumar, A. B., Battino, M. A., & Álvarez-Suárez, J. M. (2018) · Food and Chemical Toxicology · doi:10.1016/j.fct.2018.01.022 · Cited by 307

Quercetin Derivatives Are Deconjugated and Converted to Hydroxyphenylacetic Acids but Not Methylated by Human Fecal Flora in Vitro

Aura, A., O’Leary, K. A., Williamson, G., Ojala, M., Bailey, M., Puupponen‐Pimiä, R., Nuutila, A. M., Oksman‐Caldentey, K., & Poutanen, K. S. (2002) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0108056 · Cited by 306

Discovery of the curcumin metabolic pathway involving a unique enzyme in an intestinal microorganism

Hassaninasab, A., Hashimoto, Y., Tomita‐Yokotani, K., & Kobayashi, M. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016217108 · Cited by 302

Bacillus subtilis isolated from the human gastrointestinal tract

Hong, H. A., Khaneja, R., Tam, N. K. M., Cazzato, A., Tan, S., Urdaci, M. C., Brisson, A. R., Gasbarrini, A., Barnes, I., & Cutting, S. M. (2008) · Research in Microbiology · doi:10.1016/j.resmic.2008.11.002 · Cited by 296

Procyanidin Dimers Are Metabolized by Human Microbiota with 2-(3,4-Dihydroxyphenyl)acetic Acid and 5-(3,4-Dihydroxyphenyl)-γ-valerolactone as the Major Metabolites

Appeldoorn, M. M., Vincken, J., Aura, A., Hollman, P. C. H., & Gruppen, H. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf803059z · Cited by 293

Pomegranate Ellagitannin-Derived Metabolites Inhibit Prostate Cancer Growth and Localize to the Mouse Prostate Gland

Seeram, N. P., Aronson, W. J., Zhang, Y., Henning, S. M., Moro, A., Lee, R., Sartippour, M. R., Harris, D. M., Rettig, M. B., Suchard, M. A., et al. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf071303g · Cited by 293

Plant Secondary Metabolites: Occurrence, Structure And Role In The Human Diet

Crozier, A., Clifford, M. B., & Ashihara, H. (2014) · Wiley eBooks · doi:10.1002/9780470988558 · Cited by 287

Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models

Serra, A., Macià, A., Romero, M., Valls, J., Bladé, C., Arola, L., & Motilva, M. (2009) · British Journal Of Nutrition · doi:10.1017/s0007114509992741 · Cited by 284

Decomposition of Cocoa Procyanidins in the Gastric Milieu

Spencer, J. P. E., Chaudry, F., Pannala, A. S., Srai, S. K., Debnam, E. S., & Rice-Evans, C. A. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.2749 · Cited by 283

Bioavailability of Anthocyanins and Ellagitannins Following Consumption of Raspberries by Healthy Humans and Subjects with an Ileostomy

González‐Barrio, R., Borges, G., Mullen, W., & Crozier, A. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf100315d · Cited by 283

The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota

Białońska, D., Ramnani, P., Kasimsetty, S. G., Muntha, K. R., Gibson, G. R., & Ferreira, D. (2010) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.03.038 · Cited by 280

Polyphenols and Oxidative Stress in Atherosclerosis‐Related Ischemic Heart Disease and Stroke

Cheng, Y., Sheen, J.-M., Hu, W.-L., & Hung, Y. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/8526438 · Cited by 266

Anthocyanin metabolites in human urine and serum

Kay, C. D., Mazza, G., Holub, B. J., & Jian, W. (2004) · British Journal Of Nutrition · doi:10.1079/bjn20041126 · Cited by 260

Urolithins, Intestinal Microbial Metabolites of Pomegranate Ellagitannins, Exhibit Potent Antioxidant Activity in a Cell-Based Assay

Białońska, D., Kasimsetty, S. G., Khan, S. I., & Ferreira, D. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9025794 · Cited by 258

The metabolome of [2-14C](−)-epicatechin in humans: implications for the assessment of efficacy, safety and mechanisms of action of polyphenolic bioactives

Ottaviani, J. I., Borges, G., Momma, T. Y., Spencer, J. P. E., Keen, C. L., Crozier, A., & Schroeter, H. (2016) · Scientific Reports · doi:10.1038/srep29034 · Cited by 256

Malvidin-3-glucoside bioavailability in humans after ingestion of red wine, dealcoholized red wine and red grape juice

Bub, A., Watzl, B., Heeb, D., Rechkemmer, G., & Briviba, K. (2001) · European Journal of Nutrition · doi:10.1007/s003940170011 · Cited by 254

Pharmacokinetics of Anthocyanins and Antioxidant Effects after the Consumption of Anthocyanin-Rich Açai Juice and Pulp (Euterpe oleracea Mart.) in Human Healthy Volunteers

Mertens‐Talcott, S. U., Rios, J., Jilma‐Stohlawetz, P., Pacheco-Palencia, L. A., Meibohm, B., Talcott, S. T., & Derendorf, H. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf8007037 · Cited by 249

Apple Procyanidin Oligomers Absorption in Rats after Oral Administration: Analysis of Procyanidins in Plasma Using the Porter Method and High-Performance Liquid Chromatography/Tandem Mass Spectrometry

Shoji, T., Masumoto, S., Moriichi, N., Akiyama, H., Kanda, T., Ohtake, Y., & Goda, Y. (2006) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf052260b · Cited by 248

Bioavailability of (-)-epicatechin upon intake of chocolate and cocoa in human volunteers

Baba, S., Osakabe, N., Yasuda, A., Natsume, M., Takizawa, T., Nakamura, T., & Terao, J. (2000) · Free Radical Research · doi:10.1080/10715760000301151 · Cited by 241

Human studies on the absorption, distribution, metabolism, and excretion of tea polyphenols

Clifford, M. N., van der Hooft, J. J. J., & Crozier, A. (2013) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.058958 · Cited by 240

Apple Pectin and a Polyphenol-Rich Apple Concentrate Are More Effective Together Than Separately on Cecal Fermentations and Plasma Lipids in Rats

Aprikian, O., Duclos, V., Besson, C., Manach, C., Morand, C., Rémésy, C., Demigné, C., Guyot, S., & Bernalier, A. (2003) · Journal of Nutrition · doi:10.1093/jn/133.6.1860 · Cited by 238

Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients

Núñez‐Sánchez, M. Á., Garcı́a-Villalba, R., Monedero‐Saiz, T., Espin, N. V. G.-T., Gómez‐Sánchez, M. B., Sánchez‐Álvarez, C., García‐Albert, A. M., Rodríguez‐Gil, F. J., Ruiz‐Marín, M., Pastor-Quirante, F. A., et al. (2014) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201300931 · Cited by 235

The Role of Curcumin in Modulating Colonic Microbiota During Colitis and Colon Cancer Prevention

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