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Diet-Microbiota Interactions and Their Implications for Healthy Living
Open accessAbstract
It is well established that diet influences the health of an individual and that a diet rich in plant-based foods has many advantages in relation to the health and well-being of an individual. What has been unclear until recently is the large contribution of the gut microbiota to this effect. As well as providing basic nutritional requirements, the long-term diet of an animal modifies its gut microbiota. In adults, diets that have a high proportion of fruit and vegetables and a low consumption of meat are associated with a highly diverse microbiota and are defined by a greater abundance of Prevotella compared to Bacteroides, while the reverse is associated with a diet that contains a low proportion of plant-based foods. Furthermore, it is becoming increasingly clear that the effect of the microbial ecology of the gut goes beyond the local gut immune system and is implicated in immune-related disorders, such as IBS, diabetes and inflamm-ageing. In this review, we investigate the evidence that a balanced diet leads to a balanced, diverse microbiota with significant consequences for healthy ageing by focusing on conditions of interest.
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“Habitual diet plays a major role in shaping the composition of the gut microbiota, and also determines the repertoire of microbial metabolites that can influence the host.”
From High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome (2016) · cites this paper as [1]
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“A normal microbiome increases nutrient bioavailability. In order to maintain their health, GF mice should be fed a diet of higher nutrient quantity and diversity than conventional mice.156”
From The Gut Microbiome and the Brain (2014) · cites this paper as [156]
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Metadata
- Authors
- Jeffery, I., & O'Toole, P.
- Affiliations
- University College Cork (IE)
- Department of Microbiology, University College Cork, College Road, Cork, Ireland
- Corresponding author
- Jeffery, Ian
- ORCID
- Jeffery, Ian
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2013-01-17
- Volume
- 5
- Issue
- 1
- Pages
- 234-252
- ISSN
- 2072-6643 (ISSN-L)
- PMC
- PMC3571646
- OpenAlex
- W2052419633
- Cited by
- 199
- References
- 119
- Citations by year
- 2026: 7 · 2025: 6 · 2024: 9 · 2023: 13 · 2022: 20 · 2021: 21 · 2020: 22 · 2019: 16 · 2018: 9 · 2017: 16 · 2016: 14 · 2015: 15 · 2014: 20 · 2013: 11
- FWCI
- 1.88
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Nutrients (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Science Foundation Ireland
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Keywords
- gut microbiota diversity, plant-based diet, fruit and vegetable intake, meat consumption, Prevotella, Bacteroides, immune-related diseases, inflammatory bowel disease, diabetes mellitus, healthy aging
- MeSH terms
- Adult, Aging, Animals, Child, Diabetes Mellitus, Diet, Feces, Humans, Nutritional Requirements, Obesity, Inflammatory Bowel Diseases, Gastrointestinal Tract, Mice, Metagenome
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