The history and geography of human genes

The weirdest people in the world?

Henrich, J., Heine, S. J., & Norenzayan, A. (2010) · Behavioral and Brain Sciences · doi:10.1017/s0140525x0999152x · Cited by 12,641

Principal components analysis corrects for stratification in genome-wide association studies

Price, A. L., Patterson, N. J., Plenge, R. M., Weinblatt, M. E., Shadick, N. A., & Reich, D. (2006) · Nature Genetics · doi:10.1038/ng1847 · Cited by 10,248

The International HapMap Project

†The International HapMap Consortium, Genotyping centres: Baylor College of Medicine and ParAllele BioScience, Gibbs, R. A., Belmont, J. W., Hardenbol, P., Willis, T. D., Yu, F., Chinese HapMap Consortium, Yang, H., Ch'ang, L.-Y., et al. (2003) · Nature · doi:10.1038/nature02168 · Cited by 6,057

Population Structure and Eigenanalysis

Patterson, N., Price, A. L., & Reich, D. (2006) · PLoS Genetics · doi:10.1371/journal.pgen.0020190 · Cited by 5,280

Genomic Control for Association Studies

Devlin, B., & Roeder, K. (1999) · Biometrics · doi:10.1111/j.0006-341x.1999.00997.x · Cited by 3,162

Ancient Admixture in Human History

Patterson, N., Moorjani, P., Luo, Y., Mallick, S., Rohland, N., Zhan, Y., Genschoreck, T., Webster, T., & Reich, D. (2012) · Genetics · doi:10.1534/genetics.112.145037 · Cited by 2,848

Sickle-cell disease

Rees, D. C., Williams, T. N., & Gladwin, M. T. (2010) · The Lancet · doi:10.1016/s0140-6736(10)61029-x · Cited by 2,504

Genes mirror geography within Europe

Novembre, J., Johnson, T., Bryc, K., Kutalik, Z., Boyko, A. R., Auton, A., Indap, A., King, K. S., Bergmann, S., Nelson, M. R., et al. (2008) · Nature · doi:10.1038/nature07331 · Cited by 1,479

Use of Unlinked Genetic Markers to Detect Population Stratification in Association Studies

Pritchard, J. K., & Rosenberg, N. A. (1999) · The American Journal of Human Genetics · doi:10.1086/302449 · Cited by 1,198

Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates

Piel, F. B., Patil, A. P., Howes, R. E., Nyangiri, O. A., Gething, P. W., Dewi, M., Temperley, W. H., Williams, T. N., Weatherall, D. J., & Hay, S. I. (2013) · The Lancet · doi:10.1016/s0140-6736(12)61229-x · Cited by 1,196

Initial impact of the sequencing of the human genome

Lander, E. S. (2011) · Nature · doi:10.1038/nature09792 · Cited by 1,044

Genetic Heterogeneity in Human Disease

McClellan, J., & King, M.-C. (2010) · Cell · doi:10.1016/j.cell.2010.03.032 · Cited by 981

Ancient human genome sequence of an extinct Palaeo-Eskimo

Rasmussen, M., Li, Y., Lindgreen, S., Pedersen, J. S., Albrechtsen, A., Moltke, I., Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., et al. (2010) · Nature · doi:10.1038/nature08835 · Cited by 849

Beyond Western, Educated, Industrial, Rich, and Democratic (WEIRD) Psychology: Measuring and Mapping Scales of Cultural and Psychological Distance

Muthukrishna, M., Bell, A. V., Henrich, J., Curtin, C. M., Gedranovich, A., McInerney, J., & Thue, B. (2020) · Psychological Science · doi:10.1177/0956797620916782 · Cited by 704

Reconstructing Native American population history

Reich, D., Patterson, N., Campbell, D., Tandon, A., Mazieres, S., Ray, N., Parra, M. V., Rojas, W., Duque, C., Mesa, N., et al. (2012) · Nature · doi:10.1038/nature11258 · Cited by 696

Cultural group selection plays an essential role in explaining human cooperation: a sketch of the evidence.

Richerson, P., Baldini, R., Bell, A. V., Demps, K., Frost, K., Hillis, V., Mathew, S., Newton, E. K., Naar, N., Newson, L., et al. (2016) · Behavioral and Brain Sciences · doi:10.1017/s0140525x1400106x · Cited by 639

Genetic variation, classification and ‘race’

Jorde, L. B., & Wooding, S. P. (2004) · Nature Genetics · doi:10.1038/ng1435 · Cited by 637

Correlation between Genetic and Geographic Structure in Europe

Lao, O., Lu, T. T., Nothnagel, M., Junge, O., Freitag-Wolf, S., Caliebe, A., Balascakova, M., Bertranpetit, J., Bindoff, L. A., Comas, D., et al. (2008) · Current Biology · doi:10.1016/j.cub.2008.07.049 · Cited by 503

An apportionment of human DNA diversity

Barbujani, G., Magagni, A., Minch, E., & Cavalli-Sforza, L. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.9.4516 · Cited by 498

Thirty years of research on race differences in cognitive ability.

Rushton, J. P., & Jensen, A. R. (2005) · Psychology, Public Policy, and Law · doi:10.1037/1076-8971.11.2.235 · Cited by 457

Haplotype Structure and Population Genetic Inferences from Nucleotide-Sequence Variation in Human Lipoprotein Lipase

Clark, A. G., Weiss, K. M., Nickerson, D. A., Taylor, S. L., Buchanan, A., Stengård, J., Salomaa, V., Vartiainen, E., Perola, M., Boerwinkle, E., et al. (1998) · The American Journal of Human Genetics · doi:10.1086/301977 · Cited by 435

Y-chromosomal diversity in Europe is clinal and influenced primarily by geography, rather than by language

Rosser, Z. H., Zerjal, T., Hurles, M. E., Adojaan, M., Alavantic, D., Amorim, A., Amos, W., Armenteros, M., Arroyo, E., Barbujani, G., et al. (2000) · The American Journal of Human Genetics · doi:10.1086/316890 · Cited by 424

Theory and practice in quantitative genetics

Posthuma, D., Beem, A. L., de Geus, E. J. C., van Baal, G. C. M., von Hjelmborg, J. B., Iachine, I., & Boomsma, D. I. (2003) · Twin Research · doi:10.1375/136905203770326367 · Cited by 416

Journal of the Royal Society Interface

(2013) · doi:10.1098/rsif · Cited by 403

Gene-culture coevolution in the age of genomics

Richerson, P. J., Boyd, R., & Henrich, J. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914631107 · Cited by 393

The Eurasian Heartland: A continental perspective on Y-chromosome diversity

Wells, R. S., Yuldasheva, N., Ruzibakiev, R., Underhill, P. A., Evseeva, I., Blue-Smith, J., Jin, L., Su, B., Pitchappan, R., Shanmugalakshmi, S., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.171305098 · Cited by 356

Genetic evidence supports demic diffusion of Han culture

Wen, B., Li, H., Lu, D., Song, X., Zhang, F., He, Y., Li, F., Gao, Y., Mao, X., Zhang, L., et al. (2004) · Nature · doi:10.1038/nature02878 · Cited by 353

The Power of Genomic Control

Bacanu, S.-A., Devlin, B., & Roeder, K. (2000) · The American Journal of Human Genetics · doi:10.1086/302929 · Cited by 340

Where west meets east: the complex mtDNA landscape of the southwest and Central Asian corridor

Quintana-Murci, L., Chaix, R., Wells, R. S., Behar, D. M., Sayar, H., Scozzari, R., Rengo, C., Al-Zahery, N., Semino, O., Santachiara-Benerecetti, A. S., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/383236 · Cited by 338

Genetic Structure of the Han Chinese Population Revealed by Genome-wide SNP Variation

Chen, J., Zheng, H., Bei, J.-X., Sun, L., Jia, W.-H., Li, T., Zhang, F., Seielstad, M., Zeng, Y.-X., Zhang, X., et al. (2009) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2009.10.016 · Cited by 315

Features of Evolution and Expansion of Modern Humans, Inferred from Genomewide Microsatellite Markers

Zhivotovsky, L. A., Rosenberg, N. A., & Feldman, M. W. (2003) · The American Journal of Human Genetics · doi:10.1086/375120 · Cited by 300

Schizophrenia: a common disease caused by multiple rare alleles

McClellan, J. M., Susser, E., & King, M.-C. (2007) · British Journal of Psychiatry · doi:10.1192/bjp.bp.106.025585 · Cited by 296

Identification of a geographic area characterized by extreme longevity in the Sardinia island: The AKEA study

Poulain, M., Pes, G. M., Grasland, C., Carru, C., Ferrucci, L., Baggio, G., Franceschi, C., & Deiana, L. (2004) · Experimental Gerontology · doi:10.1016/j.exger.2004.06.016 · Cited by 286

A Genomewide Admixture Map for Latino Populations

Price, A. L., Patterson, N., Yu, F., Cox, D. R., Waliszewska, A., McDonald, G. J., Tandon, A., Schirmer, C., Neubauer, J., Bedoya, G., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/518313 · Cited by 282

Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene

Kayser, M., Liu, F., Janssens, A. C. J. W., Rivadeneira, F., Lao, O., van Duijn, K., Vermeulen, M., Arp, P., Jhamai, M. M., van IJcken, W. F. J., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.10.003 · Cited by 260

Tracing the Route of Modern Humans out of Africa by Using 225 Human Genome Sequences from Ethiopians and Egyptians

Pagani, L., Schiffels, S., Gurdasani, D., Danecek, P., Scally, A., Chen, Y., Xue, Y., Haber, M., Ekong, R., Oljira, T., et al. (2015) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2015.04.019 · Cited by 216

Trading genes along the silk road: mtDNA sequences and the origin of central Asian populations.

Comas, D., Calafell, F., Mateu, E., Pérez-Lezaun, A., Bosch, E., Martínez-Arias, R., Clarimon, J., Facchini, F., Fiori, G., Luiselli, D., et al. (1998) · The American Journal of Human Genetics · doi:10.1086/302133 · Cited by 239

Y-chromosomal DNA variation in Pakistan

Qamar, R., Ayub, Q., Mohyuddin, A., Helgason, A., Mazhar, K., Mansoor, A., Zerjal, T., Tyler-Smith, C., & Mehdi, S. Q. (2002) · The American Journal of Human Genetics · doi:10.1086/339929 · Cited by 236

Global human mandibular variation reflects differences in agricultural and hunter-gatherer subsistence strategies

von Cramon-Taubadel, N. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1113050108 · Cited by 211

A Common Genetic Origin for Early Farmers from Mediterranean Cardial and Central European LBK Cultures

Olalde, I., Schroeder, H., Sandoval-Velasco, M., Vinner, L., Lobón, I., Ramirez, O., Civit, S., García Borja, P., Salazar-García, D. C., Talamo, S., et al. (2015) · Molecular Biology and Evolution · doi:10.1093/molbev/msv181 · Cited by 207

DETECTING RANGE EXPANSIONS FROM GENETIC DATA

Peter, B. M., & Slatkin, M. (2013) · Evolution · doi:10.1111/evo.12202 · Cited by 173

Saami and Berbers-An Unexpected Mitochondrial DNA Link

Achilli, A., Rengo, C., Battaglia, V., Pala, M., Olivieri, A., Fornarino, S., Magri, C., Scozzari, R., Babudri, N., Santachiara-Benerecetti, A. S., et al. (2005) · The American Journal of Human Genetics · doi:10.1086/430073 · Cited by 180

The Western and Eastern Roots of the Saami—the Story of Genetic “Outliers” Told by Mitochondrial DNA and Y Chromosomes

Tambets, K., Rootsi, S., Kivisild, T., Help, H., Serk, P., Loogväli, E.-L., Tolk, H.-V., Reidla, M., Metspalu, E., Pliss, L., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/383203 · Cited by 176

Y-Chromosome Evidence for Differing Ancient Demographic Histories in the Americas

Bortolini, M.-C., Salzano, F. M., Thomas, M. G., Stuart, S., Nasanen, S. P. K., Bau, C. H. D., Hutz, M. H., Layrisse, Z., Petzl-Erler, M. L., Tsuneto, L. T., et al. (2003) · The American Journal of Human Genetics · doi:10.1086/377588 · Cited by 160

Genomic Affinities of Two 7,000-Year-Old Iberian Hunter-Gatherers

Sánchez-Quinto, F., Schroeder, H., Ramirez, O., Ávila-Arcos, M. C., Pybus, M., Olalde, I., Velazquez, A. M. V., Marcos, M. E. P., Encinas, J. M. V., Bertranpetit, J., et al. (2012) · Current Biology · doi:10.1016/j.cub.2012.06.005 · Cited by 142

A genetic landscape reshaped by recent events: Y-chromosomal insights into Central Asia

Zerjal, T., Wells, R. S., Yuldasheva, N., Ruzibakiev, R., & Tyler-Smith, C. (2002) · The American Journal of Human Genetics · doi:10.1086/342096 · Cited by 138

A predominantly indigenous paternal heritage for the Austronesian-speaking peoples of insular Southeast Asia and Oceania

Capelli, C., Wilson, J. F., Richards, M., Stumpf, M. P. H., Gratrix, F., Oppenheimer, S., Underhill, P., Pascali, V. L., Ko, T.-M., & Goldstein, D. B. (2001) · The American Journal of Human Genetics · doi:10.1086/318205 · Cited by 136

On the Use of General Control Samples for Genome-wide Association Studies: Genetic Matching Highlights Causal Variants

Luca, D., Ringquist, S., Klei, L., Lee, A. B., Gieger, C., Wichmann, H.-E., Schreiber, S., Krawczak, M., Lu, Y., Styche, A., et al. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2007.11.003 · Cited by 128

The Himalayas as a Directional Barrier to Gene Flow

Gayden, T., Cadenas, A. M., Regueiro, M., Singh, N. B., Zhivotovsky, L. A., Underhill, P. A., Cavalli-Sforza, L. L., & Herrera, R. J. (2007) · The American Journal of Human Genetics · doi:10.1086/516757 · Cited by 123

From Social to Genetic Structures in Central Asia

Chaix, R., Quintana-Murci, L., Hegay, T., Hammer, M. F., Mobasher, Z., Austerlitz, F., & Heyer, E. (2007) · Current Biology · doi:10.1016/j.cub.2006.10.058 · Cited by 111

Y-chromosome lineages trace diffusion of people and languages in southwestern Asia.

Quintana-Murci, L., Krausz, C., Zerjal, T., Sayar, S. H., Hammer, M. F., Mehdi, S. Q., Ayub, Q., Qamar, R., Mohyuddin, A., Radhakrishna, U., et al. (2001) · The American Journal of Human Genetics · doi:10.1086/318200 · Cited by 102

Worldwide polymorphism at the MC1R locus and normal pigmentation variation in humans

Makova, K., & Norton, H. (2005) · Peptides · doi:10.1016/j.peptides.2004.12.032 · Cited by 101

Sex-specific migration patterns in Central Asian populations, revealed by analysis of Y-chromosome short tandem repeats and mtDNA.

Pérez-Lezaun, A., Calafell, F., Comas, D., Mateu, E., Bosch, E., Martínez-Arias, R., Clarimón, J., Fiori, G., Luiselli, D., Facchini, F., et al. (1999) · The American Journal of Human Genetics · doi:10.1086/302451 · Cited by 101

FKBP5 polymorphism is associated with major depression but not with bipolar disorder

Szczepankiewicz, A., Leszczyńska-Rodziewicz, A., Pawlak, J., Narozna, B., Rajewska-Rager, A., Wilkosc, M., Zaremba, D., Maciukiewicz, M., & Twarowska-Hauser, J. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.04.002 · Cited by 100

The relative efficacy of functional and developmental cranial modules for reconstructing global human population history

von Cramon‐Taubadel, N. (2011) · American Journal of Physical Anthropology · doi:10.1002/ajpa.21550 · Cited by 91

Peopling of Sahul: mtDNA Variation in Aboriginal Australian and Papua New Guinean Populations

Redd, A. J., & Stoneking, M. (1999) · The American Journal of Human Genetics · doi:10.1086/302533 · Cited by 91

Evolution of a Length Polymorphism in the Human PER3 Gene, a Component of the Circadian System

Nadkarni, N. A., Weale, M. E., von Schantz, M., & Thomas, M. G. (2005) · Journal of Biological Rhythms · doi:10.1177/0748730405281332 · Cited by 76

A Novel Y-Chromosome Variant Puts an Upper Limit on the Timing of First Entry into the Americas

Seielstad, M., Yuldasheva, N., Singh, N., Underhill, P., Oefner, P., Shen, P., & Wells, R. S. (2003) · The American Journal of Human Genetics · doi:10.1086/377589 · Cited by 73

Ice Age Atlantis? Exploring the Solutrean-Clovis ‘connection’

Straus, L. G., Meltzer, D. J., & Goebel, T. (2005) · World Archaeology · doi:10.1080/00438240500395797 · Cited by 66

Consistent long-range linkage disequilibrium generated by admixture in a Bantu-Semitic hybrid population.

Wilson, J. F., & Goldstein, D. B. (2000) · The American Journal of Human Genetics · doi:10.1086/303083 · Cited by 64

General mental ability in South Asians: Data from three Roma (Gypsy) communities in Serbia

Rushton, J. P., Čvorović, J., & Bons, T. A. (2007) · Intelligence · doi:10.1016/j.intell.2006.09.002 · Cited by 55

Level of neurotoxic metals in amyotrophic lateral sclerosis: A population-based case–control study

Bocca, B., Forte, G., Oggiano, R., Clemente, S., Asara, Y., Peruzzu, A., Farace, C., Pala, S., Fois, A. G., Pirina, P., et al. (2015) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2015.10.023 · Cited by 54

Influence of Admixture and Paleolithic Range Contractions on Current European Diversity Gradients

Arenas, M., François, O., Currat, M., Ray, N., & Excoffier, L. (2013) · Molecular Biology and Evolution · doi:10.1093/molbev/mss203 · Cited by 50

Genetic features of Mongolian ethnic groups revealed by Y-chromosomal analysis

Katoh, T., Munkhbat, B., Tounai, K., Mano, S., Ando, H., Oyungerel, G., Chae, G.-T., Han, H., Jia, G.-J., Tokunaga, K., et al. (2005) · Gene · doi:10.1016/j.gene.2004.10.023 · Cited by 45

Distribution of the F374 Allele of the SLC45A2 (MATP) Gene and Founder‐Haplotype Analysis

Yuasa, I., Umetsu, K., Harihara, S., Kido, A., Miyoshi, A., Saitou, N., Dashnyam, B., Jin, F., Lucotte, G., Chattopadhyay, P. K., et al. (2006) · Annals of Human Genetics · doi:10.1111/j.1469-1809.2006.00261.x · Cited by 38

21 Genome partitioning and whole-genome analysis

Schorki, N. J. (2001) · Advances in Genetics · doi:10.1016/s0065-2660(01)42030-x · Cited by 29

The role of food storage in human niche construction: An example from Neolithic Europe

O'Brien, M. J., & Bentley, R. A. (2015) · Environmental Archaeology · doi:10.1179/1749631414y.0000000053 · Cited by 23

The Brain as a Cultural Artifact: Concepts, Actions, and Experiences within the Human Affective Niche

Gendron, M., Mesquita, B., & Barrett, L. F. (2020) · Culture, Mind, and Brain · doi:10.1017/9781108695374.010 · Cited by 20

Gender and population history: Sex bias revealed by studying genetic admixture of Ngazidja population (Comoro Archipelago)

Gourjon, G., Boëtsch, G., & Degioanni, A. (2011) · American Journal of Physical Anthropology · doi:10.1002/ajpa.21474 · Cited by 13

Perceptions of genetic testing and genomic medicine among drug users

Perlman, D. C., Gelpí-Acosta, C., Friedman, S. R., Jordan, A. E., & Hagan, H. (2015) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2014.06.013 · Cited by 12

Globalization in Prehistory: Contact, Exchange, and the 'People Without History'

(2018) · doi:10.1017/9781108573276 · Cited by 12

Bayesian estimation of partial population continuity using ancient DNA and spatially explicit simulations

Silva, N. M., Rio, J., Kreutzer, S., Papageorgopoulou, C., & Currat, M. (2018) · Evolutionary Applications · doi:10.1111/eva.12655 · Cited by 11

Inbreeding and surnames: A projection into Easter Island's past

González‐Martín, A., García‐Moro, C., Hernández, M., & Moral, P. (2006) · American Journal of Physical Anthropology · doi:10.1002/ajpa.20285 · Cited by 11

Mitochondrial DNA Footprints from Western Eurasia in Modern Mongolia

Cardinali, I., Bodner, M., Capodiferro, M. R., Amory, C., Rambaldi Migliore, N., Gomez, E. J., Myagmar, E., Dashzeveg, T., Carano, F., Woodward, S. R., et al. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2021.819337 · Cited by 8