Computer code comprehension shares neural resources with formal logical inference in the fronto-parietal network
Open accessPublished version of a preprint
Abstract
Despite the importance of programming to modern society, the cognitive and neural bases of code comprehension are largely unknown. Programming languages might ‘recycle’ neurocognitive mechanisms originally developed for natural languages. Alternatively, comprehension of code could depend on fronto-parietal networks shared with other culturally-invented symbol systems, such as formal logic and symbolic math such as algebra. Expert programmers (average 11 years of programming experience) performed code comprehension and memory control tasks while undergoing fMRI. The same participants also performed formal logic, symbolic math, executive control, and language localizer tasks. A left-lateralized fronto-parietal network was recruited for code comprehension. Patterns of activity within this network distinguish between ‘for’ loops and ‘if’ conditional code functions. In terms of the underlying neural basis, code comprehension overlapped extensively with formal logic and to a lesser degree math. Overlap with executive processes and language was low, but laterality of language and code covaried across individuals. Cultural symbol systems, including code, depend on a distinctive fronto-parietal cortical network.
AI snapshot
Written from the paper’s full text.
TL;DR
Expert programmers comprehending Python code recruited a left-lateralized fronto-parietal network that overlapped most with formal logical inference, less with math, and little with language or a simple executive-control task. Within this network, multivoxel activity patterns distinguished `for` loops from `if` conditionals.
Key findings
- Real code > fake code activated a left-lateralized network including lateral PFC (mainly BA 44/46), IPS, pMTG/STS, and early visual cortex (p<0.01 FWER).
- MVPA decoded `for` vs. `if` functions above chance in PFC (64.7%, p<0.001), IPS (67.4%, p<0.001), and pMTG (68.4%, p<0.001); early visual cortex was lower (55.7%, p=0.015; F(3,56)=4.78, p=0.0048).
- Code overlap was significantly above chance with logic, math, language, and MSIT (each p<0.001 vs. chance; p<0.005 vs. code split-half), but differed across tasks (F(3,42)=5.04, p=0.0045): overlap was highest with logic, followed by math and least with MSIT and language; logic exceeded all others, while language, math, and MSIT were statistically indistinguishable.
- Code comprehension was as left-lateralized as language (code lateralization index mean = 0.451; language = 0.393; paired t(14)=1.203, p=0.25), and individual lateralization indices for code and language were highly correlated (R²=0.658, p<0.001).
Methods
- Fifteen expert programmers (3 women; age 20–38, mean 27.4; mean 10.7 years programming experience, 5.7 years Python) completed fMRI code comprehension (real vs. fake code; `for` vs. `if`) plus separate logic/math/language localizer and MSIT tasks.
- fMRI analyses used GLM contrasts, functional ROIs from the real > fake code contrast, SVM-based MVPA to decode `for` vs. `if`, cosine similarity of binary activation maps to quantify overlap, and lateralization indices.
- Behavioral pre-tests assessed Python knowledge; in-scanner accuracy was similar for real vs. fake code (92% vs. 90%, p=0.23) and for `for` vs. `if` (both 92%, p=0.77), while fake-code and `for` trials were slower.
Limitations
- The paper states the sample was relatively small (n=15), so differences from the co-published Ivanova et al. study should be interpreted with caution and replicated.
- The paper notes that language, math, and logic were localized partly relative to each other, so shared areas across domains and their role in code comprehension remain to be addressed; it also allows that code and logic might dissociate at a finer neural scale.
- Evident from the text: participants were expert Python programmers, limiting generalizability to novices or other languages; the fake-code control was a memory task with different perceptual cues (yellow text) and slower responses, so it may not isolate code syntax/comprehension perfectly.
Model-written summary. Check it against the paper before relying on it.
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Cites
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Claims the paper makes
0 of 26 cited sources checked · 0 supported · 0 flagged
- Findingown data
Lateralization indices of code and language were highly correlated across individuals.
“Overlap with executive processes and language was low, but laterality of language and code covaried across individuals.”
- Also stated in: § fMRI results · plain
“Moreover, lateralization indices of code and language were highly correlated across individuals (R2 = 0.658, p<0.001)”
- Also stated in: § Code comprehension and language · plain
“Despite lack of direct overlap, lateralization patterns of language and coding were highly correlated across individuals that is those individuals with highly left-lateralized responses to sentences also showed highly left-lateralized responses to code.”
Quote in the paperSubstantial claim - Also stated in: § fMRI results · plain
- Findingown data
There was no relationship between code-math overlap and level of expertise, as measured by years of coding experience or coding assessment performance.
“Notably there was no relationship between overlap of code and language and level of expertise, as measured either by years of experience coding (regression against code-language overlap: R2 = 0, p=0.99; regression against code-math overlap: R2 = 0.033, p=0.52) or performance on coding assessments (regression against code-language overlap: R2 = 0.033, p=0.52; regression against code-math overlap: R”
Quote in the paperNot a substantial claim - Findingown data
Patterns of activity within the code-responsive network distinguish between for loops and if conditionals.
“Patterns of activity within this network distinguish between ‘for’ loops and ‘if’ conditional code functions.”
- Also stated in: § fMRI results · plain
“MVPA analysis revealed that for and if functions could be distinguished based on patterns of activity within PFC (accuracy = 64.7%, p<0.001), IPS (accuracy = 67.4%, p<0.001) and pMTG (accuracy = 68.4%, p<0.001).”
- Also stated in: § Discussion · hedged
“Within this code-responsive neural network, spatial patterns of activation distinguished between for vs. if code functions, suggesting that this network represents code-relevant information and is not merely activated during the coding task due to general difficulty demands.”
Quote in the paperSubstantial claim - Also stated in: § fMRI results · plain
- Findingown data
Logic activated more anterior and more extensive regions in PFC than math.
“Logic activated more anterior and more extensive regions in PFC than math.”
Quote in the paperNot a substantial claim - Findingown data
Overlap of code and MSIT was observed in IPS, precentral gyrus, and a small portion of inferior temporal sulcus.
“Overlap of code and the MSIT (hard >easy) was also observed in the IPS, precental gyrus and a small portion of the inferior temporal sulcus.”
Quote in the paperSubstantial claim
- Findingown data
Participants were slower to respond to fake as compared to real-code trials.
“Participants were slower to respond to fake as compared to real-code trials (real M = 1.73 s, SD = 0.416; fake M = 2.03 s, SD = 0.37; t(73) = 2.329, p=0.023)”
Quote in the paperNot a substantial claim - Findingown data
There was no relationship between code-language overlap and level of expertise, as measured by years of coding experience or coding assessment performance.
“Notably there was no relationship between overlap of code and language and level of expertise, as measured either by years of experience coding (regression against code-language overlap: R2 = 0, p=0.99; regression against code-math overlap: R2 = 0.033, p=0.52) or performance on coding assessments (regression against code-language overlap: R2 = 0.033, p=0.52; regression against code-math overlap: R”
Quote in the paperNot a substantial claim - Findingown data
Code comprehension recruits a left-lateralized fronto-parietal network including lateral PFC, parietal cortex (IPS), and pMTG.
“A left-lateralized fronto-parietal network was recruited for code comprehension.”
- Also stated in: § fMRI results · plain
“As compared to fake code, real-code elicited activation in a left-lateralized network of regions, including the lateral PFC (middle/inferior frontal gyri, inferior frontal sulcus; mainly BA 44 and 46, with partial activation in BA 6, 8, 9, 10, 47), the parietal cortex (the IPS, angular, and supramarginal gyri; BA 7) and the pMTG and superior temporal sulcus (BA 22 and 37).”
- Also stated in: § Discussion · plain
“A consistent network of left-lateralized regions was activated across individuals during Python code comprehension. This network included the intraparietal sulcus (IPS), several regions within the lateral PFC and the posterior-inferior aspect of the middle temporal gyrus (pMTG).”
Quote in the paperSubstantial claim - Also stated in: § fMRI results · plain
- Findingown data
Code overlapped with language in portions of inferior frontal gyrus and posterior superior temporal sulcus/middle temporal gyrus.
“Finally, code overlapped with language (language >math) in portions of the inferior frontal gyrus and the posterior aspect of the superior temporal sulcus/middle temporal gyrus.”
Quote in the paperNot a substantial claim - Findingown data
Code comprehension was as left-lateralized as language.
“Analyses of individual lateralization indices showed that indeed, code comprehension was as left-lateralized as language (Code lateralization index mean = 0.451, one sample t-test against 0: t(14) = 5.501, p<0.001; Language mean = 0.393, t(14) = 5.523, p<0.001; paired t-test between code and language: t(14) = 1.203, p=0.25).”
Quote in the paperNot a substantial claim - Findingown data
Overlap of code with logic and math was observed in IPS, PFC, and a posterior portion of inferior temporal gyrus.
“The overlap of code with logic and math was observed in the IPS, PFC, and a posterior portion of the inferior temporal gyrus (IT).”
Quote in the paperSubstantial claim - Findingown data
The language/math/logic localizer task activated previously identified networks involved in these respective domains.
“The language/math/logic localizer task activated previously identified networks involved in these respective domains.”
Quote in the paperSubstantial claim - Findingown data
Random-effects whole-brain univariate analysis for the real > fake code contrast revealed four major clusters in the left hemisphere: the intraparietal sulcus (IPS), the posterior middle temporal gyrus (pMTG), the lateral PFC, and the early visual cortex (Occ).
“First, random-effects whole-brain univariate analysis for the real >fake code contrast revealed four major clusters in the left hemisphere: the intraparietal sulcus (IPS), the posterior middle temporal gyrus (pMTG), the lateral PFC, and the early visual cortex (Occ).”
Quote in the paperSubstantial claim - Interpretationown data
Neural overlap between logic and code is specific and not fully accounted for by general involvement of the central executive system.
“These findings suggest that neural overlap between logic and code is specific, and not fully accounted for by the general involvement of the central executive system.”
Quote in the paperSubstantial claim - Premisereasoning
None of the prior studies localized neural networks involved in language, or cultural symbol systems such as math and logic, in the same participants, leaving direct neural overlap unanswered.
“None of these prior studies localized neural networks involved in language, or cultural symbol systems such as math and logic, in the same participants — leaving the question of direct neural overlap unanswered.”
Quote in the paperSubstantial claim - Interpretationown data
Culturally-invented symbol systems, including code comprehension, formal logic, and math, depend on a common fronto-parietal network including the executive system.
“Cultural symbol systems, including code, depend on a distinctive fronto-parietal cortical network.”
- Also stated in: § Code overlaps with logic · hedged
“The present evidence suggests that culturally-invented symbol systems (i.e. code comprehension, formal logic and math) depend on a common fronto-parietal network, including the executive system.”
- Also stated in: § Conclusions · plain
“Rather than recycling domain-specific cortical mechanisms for language, code, like formal logic and math, depends on a subset of the domain general executive system, including anterior prefrontal areas.”
Quote in the paperSubstantial claim - Also stated in: § Code overlaps with logic · hedged
- Premisecitation
The fronto-parietal network overlaps partially with the central executive/working memory system.
“This fronto-parietal network overlaps partially with the so-called central executive/working memory system, which is implicated in a variety of cognitive tasks that involve maintaining and manipulating information in working memory, processes that are part and parcel of understanding and writing code (Brooks, 1977; Duncan, 2010; Letovsky, 1987; Miller and Cohen, 2001; Soloway and Ehrlich, 1984;”
Quote in the paperSubstantial claim0 of 3 sources checked - Premisecitation
Two studies observed larger fronto-parietal responses when comparing code writing and editing to prose writing and editing.
“Two studies observed larger fronto-parietal responses when comparing code writing and editing to prose writing and editing (Floyd et al., 2017; Krueger et al., 2020).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites Floyd et al., 2017
Not checked in the free run.
- cites Krueger et al., 2020
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- Premisecitation
Logic and math recruit a fronto-parietal network including dorsolateral PFC and IPS as well as putative symbol representations in inferior temporal cortex.
“Rather than recruiting perisylvian fronto-temporal areas, logic and math recruit a fronto-parietal network, including the dorsolateral prefrontal cortex (PFC) and the intraparietal sulcus (IPS) as well as putative symbol representations (i.e. numberform area) in inferior temporal cortex (Amalric and Dehaene, 2016; Coetzee and Monti, 2018; Goel et al., 2007; Monti et al., 2009).”
Quote in the paperSubstantial claim0 of 3 sources checked- cites Amalric and Dehaene, 2016 source
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- cites Coetzee and Monti, 2018
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- cites Goel et al., 2007
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- Interpretationown data
The neural basis of code is distinct from the perisylvian fronto-temporal language network.
“By contrast, the neural basis of code is distinct from the perisylvian fronto-temporal language network.”
- Also stated in: § Code comprehension and language · hedged
“Nevertheless, on the whole, the results do not support the hypothesis that the language system is recycled for code comprehension (see also Ivanova et al, in press).”
Quote in the paperSubstantial claim - Also stated in: § Code comprehension and language · hedged
- Interpretationreasoning
The degree of prefrontal involvement in code comprehension may depend in part on whether variable manipulation is involved.
“The degree of prefrontal involvement in code comprehension may therefore depend in part on whether variable manipulation is involved.”
Quote in the paperNot a substantial claim - Interpretationreasoning
Code-relevant neural representations might be enabled by the language system, even though they are distinct from it.
“Ontogenetically, code-relevant neural representations might be enabled by the language system, even though they are distinct from it.”
Quote in the paperNot a substantial claim - Interpretationreasoning
The executive system may be uniquely suited as a flexible learning mechanism capable of supporting an array of cultural symbol systems acquired in adulthood.
“The executive system may be uniquely suited as a flexible learning mechanism capable of supporting an array of cultural symbol systems acquired in adulthood.”
Quote in the paperSubstantial claim - Interpretationreasoning
Domain-specific systems, like the perisylvian fronto-temporal language network, are not always amenable for recycling by cultural inventions.
“These observations suggest that domain-specific systems, like the perisylvian fronto-temporal language network, are not always amenable for ‘recycling’ by cultural inventions.”
Quote in the paperSubstantial claim
- May combine two claims. 22
- Classified as probably not a substantial claim. 39
May combine two claims.
Findingown dataThe MSIT hard > easy contrast activated a fronto-parietal network including IPS, with lateral frontal activation posterior and close to the precentral gyrus.
“The MSIT hard >easy contrast also activated a fronto-parietal network including the IPS, however, the activation in the lateral frontal cortex was posterior and close to the precentral gyrus.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataCode comprehension (real > fake) overlapped significantly above chance with logic, math, language, and MSIT localizer contrasts.
“Code comprehension (real >fake) overlapped significantly above chance with all localizer tasks: logic, math, language and MSIT (each task compared to chance p’s < 0.001, compared to code split-half overlap p’s < 0.005)”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor vs if decoding was also above chance in early visual cortex, but decoding accuracy there was lower than in PFC, IPS, and pMTG.
“for and if functions could also be distinguished within the early visual cortex (accuracy = 55.7%, p=0.015), however, decoding accuracy was lower than in the other regions (F(3, 56)=4.78, p=0.0048)”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataOverlap with logic was significantly higher than with all other tasks, while overlaps with language, math, and MSIT were statistically indistinguishable from each other.
“Overlap with logic was significantly higher than with all other tasks, while the overlaps with the other three tasks (language, math, MSIT) were statistically indistinguishable from each other (post-hoc paired t-tests, FDR-corrected p’s < 0.05)”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataCode comprehension overlapped most with logic, followed by math, and least with MSIT and language.
“In terms of the underlying neural basis, code comprehension overlapped extensively with formal logic and to a lesser degree math. Overlap with executive processes and language was low, but laterality of language and code covaried across individuals.”
- Also stated in: § fMRI results · plain
“Code comprehension overlapped most with logic (logic >language), followed by math and least with MSIT and language”
- Also stated in: § Discussion · plain
“In overlap analyses, the code comprehension network was most similar to the fronto-parietal system involved in formal logical reasoning and to a lesser degree math. By contrast overlap with the perisylvian fronto-temporal language network is low.”
Quote in the paperSubstantial claim- Also stated in: § fMRI results · plain
Probably not a substantial claim: may not pass S3 (load-bearing).
FindingreasoningThe current results are consistent with the co-published study by Ivanova and colleagues.
“The current results are consistent with the co-published study by Ivanova and colleagues.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataOn average, participants answered 64.6% (SD = 16.6%) of the difficult out-of-scanner exercise questions correctly, with a range of 37.5-93.75%.
“On average, the participants got 64.6% (SD = 16.6%) of the questions correct (range: 37.5–93.75%).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataAll participants had at least 5 years of programming experience and at least 3 years of Python experience.
“All participants had at least 5 years of programming experience (range: 5–22, mean = 10.7, SD = 5.2), and at least 3 years of experience with Python (range: 3–9, mean = 5.7, SD = 1.8).”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Study design and conductreasoningFake code stimuli preserved the perceptual and lexical elements of real code but were devoid of syntactic structure.
“Each fake function preserved the perceptual and lexical elements of a real function, but was devoid of syntactic structure.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationOnly a handful of previous studies have looked at the neural basis of code processing.
“Only a handful of previous studies have looked at the neural basis of code processing (Duraes et al., 2016; Floyd et al., 2017; Ikutani and Uwano, 2014; Peitek et al., 2018; Siegmund et al., 2014; Huang et al., 2019).”
Quote in the paperNot a substantial claim0 of 3 sources checkedProbably not a substantial claim: may not pass S4 (based).
Study design and conductnone givenOverlap analyses control for the overall number of activated vertices in each contrast.
“Note that overlap analyses control for the overall number of activated vertices in each contrast.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataThe code-responsive network represents code-relevant information and is not merely activated due to general difficulty demands.
“suggesting that this network represents code-relevant information and is not merely activated during the coding task due to general difficulty demands.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataSeventeen individuals participated; one did not complete due to claustrophobia, another was excluded for excessive movement, and data from the remaining fifteen were reported.
“Seventeen individuals participated in the study; one did not complete the tasks due to claustrophobia, and another was excluded from analyses due to excessive movement (>2 mm). We report data from the remaining fifteen individuals (three women, age range 20–38, mean age = 27.4, SD = 5.0).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe current sample is relatively small (n = 15), so differences between the current study and the Ivanova findings should be interpreted with caution and replicated in future work.
“Notably, since the current sample is relatively small (n = 15), any differences between the current study and the Ivanova findings should be interpreted with caution and replicated in future work.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationWithin PFC, logic recruits more anterior regions associated with advanced reasoning and symbol manipulation.
“Within the PFC, logic in particular recruits more anterior regions associated with more advanced forms of reasoning and symbol manipulation (Coetzee and Monti, 2018; Ramnani and Owen, 2004).”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Coetzee and Monti, 2018
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- cites Ramnani and Owen, 2004 source
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Premisenone givenOther culturally-invented symbol systems, such as formal logic and mathematics, do not appear to depend on the same neural network as natural language.
“Other culturally-invented symbol systems, such as formal logic and mathematics do not appear to depend on the same neural network as natural language.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenThe order of presentation of the functions was pseudo-randomized and balanced across participants.
“The order of the presentation of the functions was pseudo-randomized and balanced across participants.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing). May combine two claims.
Interpretationown dataThe relationship between code and language may be ontogenetic as well as phylogenetic.
“This intriguing observation suggests that the relationship between code and language may be ontogenetic as well as phylogenetic.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Study design and conductown dataA bootstrapping approach was used to test whether each observed cosine similarity value was significantly above the empirical lower bound.
“We used a bootstrapping approach to test whether each observed cosine similarity value was significantly above the empirical lower bound.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenIdentical trials never appeared in succession, and the order of the trials was different across all 8 blocks of the same kind.
“Identical trials never appeared in succession, and the order of the trials was different across all 8 blocks of the same kind.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Study design and conductown dataThe cosine similarities of code to each of the localizer tasks were compared using repeated-measure ANOVA and post-hoc pairwise comparisons with false discovery rate (FDR) correction.
“The cosine similarities of code to each of the localizer tasks was then compared using repeated-measure ANOVA and post-hoc pairwise comparisons with false discovery rate (FDR) correction.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe perisylvian fronto-temporal language network shows enhanced activity for stimuli that contain meaningful lexical items and sentence-level syntax.
“The perisylvian fronto-temporal language network shows enhanced activity for stimuli that contain meaningful lexical items and sentence-level syntax (e.g. Fedorenko et al., 2016).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Fedorenko et al., 2016 source
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Study design and conductreasoningFake functions were derived from real functions, preserving the words, digits and operators of the real functions, but none of the scrambled lines comprised an executable Python statement.
“Because fake functions were derived from real functions, the words, digits and operators that existed in real functions were preserved; however, none of the scrambled lines comprised an executable Python statement.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationPrevious studies have shown that sentences with content words lead to larger responses in the perisylvian fronto-temporal language network than spoken equations or logical statements with variables.
“Although all of the tasks in the language/math/logic localizer contain language stimuli, previous studies have shown that sentences with content words lead to larger responses in the perisylvian fronto-temporal language network than spoken equations or logical statements with variables (Kanjlia et al., 2016; Monti et al., 2009; Monti et al., 2012).”
Quote in the paperNot a substantial claim0 of 3 sources checkedClassified as probably not a substantial claim. May combine two claims.
PremisecitationThe multi-source interference task (MSIT) engages executive control processes and localizes the multiple-demand network.
“The multi-source interference task (MSIT) was adapted from Bush and Shin, 2006 to engage executive control processes and localize the multiple-demand network.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Bush and Shin, 2006
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Study design and conductnone givenA nonparametric permutation test was further implemented to cluster-correct at p<0.01 family-wise error rate.
“A nonparametric permutation test was further implemented to cluster-correct at p<0.01 family-wise error rate.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Study design and conductreasoningThe cosine similarity measure controls for overall vector length (i.e. the overall number of active voxels in each contrast).
“Note that this measure controls for overall vector length (i.e. the overall number of active voxels in each contrast).”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
PremisecitationWhen comprehension of code was compared to detection of syntactic errors in code, activity in both fronto-parietal and putative language areas was observed.
“When comprehension of code was compared to detection of syntactic errors in code, activity in both fronto-parietal and putative language areas was observed (Siegmund et al., 2014, Siegmund, 2017).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites Siegmund et al., 2014 source
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- cites Siegmund, 2017
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PremisecitationPrevious studies have found that responses to language, logic and math when compared to each other were similar to what was observed for each domain relative to independent control conditions.
“Furthermore, previous studies have found that responses to language, logic and math when compared to each other were similar to what was observed for each domain relative to independent control conditions (e.g. sentences relative to lists of non-words for language, and easy vs. hard logic problems; Kanjlia et al., 2016; Monti et al., 2009, Monti et al., 2012).”
Quote in the paperNot a substantial claim0 of 3 sources checkedProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenParticipants were divided into two groups such that the variants of the functions were counterbalanced across groups, and the same participant never saw different variants of the same function.
“Participants were divided into two groups such that the variants of the functions were counterbalanced across groups; the same participant never saw different variants of the same function.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Study design and conductnone givenFor the group-level analysis across participants, random-effects models were applied, and the models were corrected for multiple comparisons at vertex level with p<0.05 false discovery rate (FDR) across the whole brain.
“For the group-level analysis across participants, random-effects models were applied, and the models were corrected for multiple comparisons at vertex level with p<0.05 false discovery rate (FDR) across the whole brain.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
PremisecitationComputer coding, mathematics, and logic all involve manipulation of arbitrary variables without inherent meaning according to a set of learned rules.
“Computer coding, mathematics and logic, all involve manipulation of arbitrary variables without inherent meaning (e.g. X, Y, input, ii) according to a set of learned rules (McCoy and Burton, 1988).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites McCoy and Burton, 1988
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Study design and conductnone givenThe order of the blocks was balanced within and between participants.
“The order of the blocks was balanced within and between participants.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim.
Study design and conductreasoningThe empirical lower bound was calculated separately for each localizer task to account for differences in the number of activated vertices across tasks.
“The empirical lower bound was calculated separately for each localizer task to account for differences in the number of activated vertices across tasks.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenThe order of the functions was permuted systematically such that each participant saw a unique order.
“We permuted the order of the functions systematically such that each participant saw a unique order (see the subsection ‘algorithm for stimulus permutation’ in the appendix).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenThe correct response was 'true' for half of the real-code trials and half of the fake code trials.
“The correct response was ‘true’ for half of the real-code trials and half of the fake code trials.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Study design and conductreasoningThe normalization eliminates any difference in the baselines of the for and if conditions while preserving distinctive spatial patterns.
“The purpose of the normalization is to eliminate any difference in the baselines of the two conditions while preserving distinctive spatial patterns.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenAll 48 statement pairs from each condition were unique and appeared once throughout the experiment.
“All 48 statement pairs from each condition were unique and appeared once throughout the experiment.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductreasoningTo help participants distinguish between real and fake code trials and to prevent them from erroneously attempting to parse fake code, real-code appeared in white text and fake code in yellow text.
“To help participants distinguish between real and fake code trials and to prevent the participants from erroneously attempting to parse fake code, real-code appeared in white text and fake code in yellow text.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenIn half of the trials, the correct answer was 'true'.
“In half of the trials, the correct answer was ‘true’.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
InterpretationcitationThe fronto-parietal system might be inherently more flexible throughout the lifespan and thus more capable of taking on new cultural skills.
“The fronto-parietal system might be inherently more flexible throughout the lifespan and thus more capable of taking on new cultural skills (Riley et al., 2018).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Riley et al., 2018 source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationThe difficult out-of-scanner exercise questions were designed to cover some of the objectives specified in the Certified Associate in Python Programming Certification exam syllabus.
“The questions were designed by the experimenter to cover some of the objectives specified in the exam syllabus of the Certified Associate in Python Programming Certification held by the Python Institute (https://pythoninstitute.org/certification/pcap-certification-associate/pcap-exam-syllabus/).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites https://pythoninstitute.org/certification/pcap-certification-associate/pcap-exam-syllabus/
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenCovariates of no interest were included to account for confounds related to white matter, cerebral spinal fluid, and motion spikes.
“Covariates of no interest were included to account for confounds related to white matter, cerebral spinal fluid, and motion spikes.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenOrder of trials was counterbalanced across participants in two lists.
“Order of trials was counterbalanced across participants in two lists.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenTrial order was arranged such that all 12 interference trials appeared exactly twice in an interference block, and all three control trials appeared exactly six times in a control block.
“Trial order was arranged such that all 12 interference trials appeared exactly twice in an interference block, and all three control trials appeared exactly six times in a control block.”
Quote in the paperNot a substantial claim
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
fMRI reveals that the language network responds reliably when people listen to, read, or generate sentences, but not when they perform arithmetic tasks, engage in logical reasoning, understand computer programs, listen to music, categorize objects or events, reason about people's mental states, or process non-verbal communicative information like facial expressions or gestures.
“it responds reliably when people listen to, read, or generate sentences, but not when they perform arithmetic tasks, engage in logical reasoning, understand computer programs, listen to music, categorize objects or events, reason about people’s mental states, or process non-verbal communicative information like facial expressions or gestures [37, 41, 42, 43, 44, 45, 46, 47, 48].”
From Dissociating language and thought in large language models (2024) · cites this paper as [46]
Statistics recomputed
Every reported test result, recomputed from its test statistic and degrees of freedom. A result shows as not adding up only once an independent check has confirmed it.
- Not confirmedF(3, 56) = 4.78reported p = .0048 · recomputed p = .005
“F(3, 56)=4.78, p = .0048”
- Consistentt(73) = 2.329reported p = .023 · recomputed p = .023
“t(73) = 2.329, p = .023”
- Consistentt(58) = 2.127reported p = .038 · recomputed p = .038
“t(58) = 2.127, p = .038”
- ConsistentF(2, 42) = 18.29reported p < .001 · recomputed p < .001
“F(2, 42)=18.29, p < .001”
- ConsistentF(2, 42) = 7.42reported p = .0017 · recomputed p = .002
“F(2, 42)=7.42, p = .0017”
- Consistentt(28) = -1.363reported p = .18 · recomputed p = .184
“t(28) = −1.363, p = .18”
- Consistentt(28) = 8.59reported p < .001 · recomputed p < .001
“t(28)=8.59, p < .001”
- ConsistentF(3, 42) = 5.04reported p = .0045 · recomputed p = .005
“F(3,42) = 5.04, p = .0045”
- Consistentt(14) = 5.501reported p < .001 · recomputed p < .001
“t(14) = 5.501, p < .001”
- Consistentt(14) = 5.523reported p < .001 · recomputed p < .001
“t(14) = 5.523, p < .001”
- Consistentt(14) = 1.203reported p = .25 · recomputed p = .249
“t(14) = 1.203, p = .25”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Control-trial counts do not fill an MSIT block
MinorThe paper says each control block contains 24 trials, but its stated schedule of three control-trial types appearing six times each yields only 18 trials.
Reported 24 · recomputed 18
“Trial order was arranged such that all 12 interference trials appeared exactly twice in an interference block, and all three control trials appeared exactly six times in a control block.”
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Cited by
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Program Comprehension and Code Complexity Metrics: An fMRI Study
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The Language Network Is Recruited but Not Required for Nonverbal Event Semantics
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Language in Brains, Minds, and Machines
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The Language Network Reliably “Tracks” Naturalistic Meaningful Nonverbal Stimuli
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Left-Hemisphere Cortical Language Regions Respond Equally to Observed Dialogue and Monologue
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Constructed languages are processed by the same brain mechanisms as natural languages
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The language network is recruited but not required for non-verbal event semanticsPreprint
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Contribution of the language network to the comprehension of Python programming code.
Liu, Y.-F., Wilson, C., & Bedny, M. (2024) · Brain and Language · doi:10.1016/j.bandl.2024.105392 · Cited by 5 · see citing works
Self-citationVlašić, G., Dabić, M., & Krupka, Z. (2024) · Strategic Change · doi:10.1002/jsc.2578 · Cited by 8 · see citing works
Situational States Influence on Team Workload Demands in Cyber Defense Exercise
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Role of the EEG Theta Network During Software Production: A Connectivity Study
Calcagno, A., Coelli, S., Amendola, C., Pirovano, I., Re, R., Medeiros, J., Carvalho, P., Madeira, H., & Bianchi, A. M. (2023) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2023.3299834 · Cited by 6 · see citing works
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Tsai, M., Chien, F. P., Sun, W.-T., & Jha, N. K. (2025) · Computers & Education · doi:10.1016/j.compedu.2025.105430 · Cited by 5 · see citing works
Performance and Attrition in Information Technology Studies; A Survey of Students' Viewpoints
Virkki, O. T. (2023) · IEEE Global Engineering Education Conference (EDUCON) · doi:10.1109/educon54358.2023.10125231 · Cited by 5 · see citing works
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A 3.5-minute-long reading-based fMRI localizer for the language network
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What Can Computer Science Educators Learn From the Failures of Top-Down Pedagogy?
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Evidence from formal logical reasoning reveals that the language of thought is not natural language
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On the Influence of the Baseline in Neuroimaging Experiments on Program Comprehension
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Hints Help Finding and Fixing Bugs Differently in Python and Text-Based Program Representations
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Learning to Program “Recycles” Preexisting Frontoparietal Population Codes of Logical Algorithms
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Toward a theory on programmer’s block inspired by writer’s block
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Animacy semantic network supports causal inferences about illnessPreprint
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Non-linguistic Thinking as an Effective Tool for Innovation in Education
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Projecting Computer Languages for a Protean Interaction
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Programming education in the AI era
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- Authors
- Liu, Y.-F., Kim, J., Wilson, C., & Bedny, M.
- Affiliations
- Johns Hopkins University, Baltimore, United States
- Johns Hopkins University (US)
- Venue
- eLife
- Publisher
- eLife Sciences Publications, Ltd
- Published
- 2020-12-15
- Volume
- 9
- ISSN
- 2050-084X (ISSN-L)
- PMC
- PMC7738180
- OpenAlex
- W3112191977
- Semantic Scholar
- d6d1a983418a499e39c936e7e5ec2ed489645165
- Cited by
- 64
- References
- 103
- Citations by year
- 2026: 10 · 2025: 13 · 2024: 18 · 2023: 5 · 2022: 7 · 2021: 8 · 2020: 2 · 2019: 1
- FWCI
- 2.95
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- eLife (publishedVersion, cc-by)
- bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Johns Hopkins University
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neurobiology of Language and Bilingualism
- Physical Sciences › Computer Science › Computer Science Applications › Teaching and Learning Programming
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- program comprehension, programming languages, frontoparietal network, formal logic, symbolic computation, executive function, language lateralization, expert programmers, for loops, if statements
- MeSH terms
- Adult, Brain Mapping, Cognition, Female, Frontal Lobe, Humans, Functional Laterality, Magnetic Resonance Imaging, Male, Neural Pathways, Parietal Lobe, Software, Comprehension, Young Adult, Executive Function
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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