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Effects of High-Intensity Strength Training on Multiple Risk Factors for Osteoporotic Fractures: A Randomized Controlled Trial
Abstract
OBJECTIVE: To determine how multiple risk factors for osteoporotic fractures could be modified by high-intensity strength training exercises in postmenopausal women. DESIGN: Randomized controlled trial of 1-year duration. SETTING: Exercise laboratory at Tufts University, Boston, Mass. POPULATION: Forty postmenopausal white women, 50 to 70 years of age, participated in the study; 39 women completed the study. The subjects were sedentary and estrogen-deplete. INTERVENTIONS: High-intensity strength training exercises 2 days per week using five different exercises (n = 20) vs untreated controls (n = 19). MAIN OUTCOME MEASURES: Dual energy x-ray absorptiometry for bone status, one repetition maximum for muscle strength, 24-hour urinary creatinine for muscle mass, and backward tandem walk for dynamic balance. RESULTS: Femoral neck bone mineral density and lumbar spine bone mineral density increased by 0.005 +/- 0.039 g/cm2 (0.9% +/- 4.5%) (mean +/- SD) and 0.009 +/- 0.033 g/cm2 (1.0% +/- 3.6%), respectively, in the strength-trained women and decreased by -0.022 +/- 0.035 g/cm2 (-2.5% +/- 3.8%) and -0.019 +/- 0.035 g/cm2 (-1.8% +/- 3.5%), respectively, in the controls (P = .02 and .04). Total body bone mineral content was preserved in the strength-trained women (+2.0 +/- 68 g; 0.0% +/- 3.0%) and tended to decrease in the controls (-33+77 g; -1.2% +/- 3.4%, P = .12). Muscle mass, muscle strength, and dynamic balance increased in the strength-trained women and decreased in the controls (P = .03 to < .001). CONCLUSIONS: High-intensity strength training exercises are an effective and feasible means to preserve bone density while improving muscle mass, strength, and balance in postmenopausal women.
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Cites
Exercise training and nutritional supplementation for physical frailty in very elderly people
Fiatarone, M. A., O'Neill, E. F., Ryan, N. D., Clements, K. M., Solares, G. R., Nelson, M. E., Roberts, S. B., Kehayias, J. J., Lipsitz, L. A., & Evans, W. J. (1994) · New England Journal of Medicine · doi:10.1056/nejm199406233302501 · Cited by 2,857
Self-citationBone density at various sites for prediction of hip fractures
Cummings, S. R., Browner, W., Cummings, S. R., Black, D. M., Nevitt, M. C., Browner, W., Genant, H. K., Cauley, J., Ensrud, K., Scott, J., et al. (1993) · The Lancet · doi:10.1016/0140-6736(93)92555-8 · Cited by 2,446
PHYSICAL ACTIVITY AS AN INDEX OF HEART ATTACK RISK IN COLLEGE ALUMNI1
PAFFENBARGER, R. S., WING, A. L., & HYDE, R. T. (1978) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a112608 · Cited by 1,980
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Child abuse: Adolescent records vs. adult recall
Femina, D. D., Yeager, C. A., & Lewis, D. O. (1990) · Child Abuse & Neglect · doi:10.1016/0145-2134(90)90033-p · Cited by 8,820
Exercise and Physical Activity for Older Adults
Chodzko-Zajko, W. J., Proctor, D. N., Fiatarone Singh, M. A., Minson, C. T., Nigg, C. R., Salem, G. J., & Skinner, J. S. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181a0c95c · Cited by 5,153
A 30-s chair-stand test as a measure of lower body strength in community-residing older adults.
Jones, C. J., Rikli, R. E., & Beam, W. C. (1999) · Research Quarterly for Exercise and Sport · doi:10.1080/02701367.1999.10608028 · Cited by 2,921
Evidence for prescribing exercise as therapy in chronic disease
Pedersen, B. K., & Saltin, B. (2006) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/j.1600-0838.2006.00520.x · Cited by 1,384
Fragala, M. S., Cadore, E. L., Dorgo, S., Izquierdo, M., Kraemer, W. J., Peterson, M. D., & Ryan, E. D. (2019) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003230 · Cited by 1,290
Progressive resistance strength training for improving physical function in older adults
Liu, C.-J., & Latham, N. K. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002759.pub2 · Cited by 1,258
Williams, M. A., Haskell, W. L., Ades, P. A., Amsterdam, E. A., Bittner, V., Franklin, B. A., Gulanick, M., Laing, S. T., & Stewart, K. J. (2007) · Circulation · doi:10.1161/circulationaha.107.185214 · Cited by 1,211
Physical Activity and Bone Health
Kohrt, W. M., Bloomfield, S. A., Little, K. D., Nelson, M. E., & Yingling, V. R. (2004) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000142662.21767.58 · Cited by 1,043
Self-citationPrevalence of sarcopenia and predictors of skeletal muscle mass in healthy, older men and women
Iannuzzi-Sucich, M., Prestwood, K. M., & Kenny, A. M. (2002) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/57.12.m772 · Cited by 890
Castaneda, C., Layne, J. E., Munoz-Orians, L., Gordon, P. L., Walsmith, J., Foldvari, M., Roubenoff, R., Tucker, K. L., & Nelson, M. E. (2002) · Diabetes Care · doi:10.2337/diacare.25.12.2335 · Cited by 844
Self-citationResistance Training is Medicine: Effects of Strength Training on Health
Westcott, W. L. (2012) · Current Sports Medicine Reports · doi:10.1249/jsr.0b013e31825dabb8 · Cited by 778
Physical Activity/Exercise and Type 2 Diabetes
Sigal, R. J., Kenny, G. P., Wasserman, D. H., & Castaneda-Sceppa, C. (2004) · Diabetes Care · doi:10.2337/diacare.27.10.2518 · Cited by 763
Tucker, K. L., Hannan, M. T., Chen, H., Cupples, L. A., Wilson, P. W., & Kiel, D. P. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.4.727 · Cited by 705
A Meta-analysis to Determine the Dose Response for Strength Development
RHEA, M. R., ALVAR, B. A., BURKETT, L. N., & BALL, S. D. (2003) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000053727.63505.d4 · Cited by 666
Wolff, I., van Croonenborg, J. J., Kemper, H. C. G., Kostense, P. J., & Twisk, J. W. R. (1999) · Osteoporosis International · doi:10.1007/s001980050109 · Cited by 589
Weight lifting in women with breast-cancer-related lymphedema
Schmitz, K. H., Ahmed, R. L., Troxel, A., Cheville, A., Smith, R., Lewis-Grant, L., Bryan, C. J., Williams-Smith, C. T., & Greene, Q. P. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810118 · Cited by 578
Handelsman, Y., Bloomgarden, Z. T., Grunberger, G., Umpierrez, G., Zimmerman, R. S., Bailey, T. S., Blonde, L., Bray, G. A., Cohen, A. J., Dagogo-Jack, S., et al. (2015) · Endocrine Practice · doi:10.4158/ep15672.glsuppl · Cited by 559
Handelsman, Y., Mechanick, J. I., Blonde, L., Grunberger, G., Bloomgarden, Z. T., Bray, G. A., Dagogo-Jack, S., Davidson, J. A., Einhorn, D., Ganda, O., et al. (2011) · Endocrine Practice · doi:10.4158/ep.17.s2.1 · Cited by 513
Exercise comes of age: rationale and recommendations for a geriatric exercise prescription
Singh, M. A. F. (2002) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/57.5.m262 · Cited by 485
Latham, N. K., Anderson, C. S., Lee, A., Bennett, D. A., Moseley, A., Cameron, I. D., & For The Fitness Collaborative Group (2003) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2003.51101.x · Cited by 463
Taaffe, D. R., Duret, C., Wheeler, S., & Marcus, R. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb05201.x · Cited by 426
Exercise and Bone Mass in Adults
Guadalupe-Grau, A., Fuentes, T., Guerra, B., & Calbet, J. A. L. (2009) · Sports Medicine · doi:10.2165/00007256-200939060-00002 · Cited by 397
Asikainen, T.-M., Kukkonen-Harjula, K., & Miilunpalo, S. (2004) · Sports Medicine · doi:10.2165/00007256-200434110-00004 · Cited by 355
The benefits of strength training for older adults
SEGUIN, R. (2003) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(03)00177-6 · Cited by 354
The effects of progressive resistance training on bone density: a review
LAYNE, J. E., & NELSON, M. E. (1999) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199901000-00006 · Cited by 329
Self-citationHigher direct medical costs associated with physical inactivity
Pratt, M., Macera, C. A., & Wang, G. (2000) · The Physician and Sportsmedicine · doi:10.3810/psm.2000.10.1237 · Cited by 312
Dose-response of physical activity and low back pain, osteoarthritis, and osteoporosis
VUORI, I. M. (2001) · Medicine and Science in Sports and Exercise · doi:10.1097/00005768-200106001-00026 · Cited by 306
Martyn-St James, M., & Carroll, S. (2009) · British Journal of Sports Medicine · doi:10.1136/bjsm.2008.052704 · Cited by 299
Pu, C. T., Johnson, M. T., Forman, D. E., Hausdorff, J. M., Roubenoff, R., Foldvari, M., Fielding, R. A., & Singh, M. A. F. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.6.2341 · Cited by 290
Ivey, F. M., Roth, S. M., Ferrell, R. E., Tracy, B. L., Lemmer, J. T., Hurlbut, D. E., Martel, G. F., Siegel, E. L., Fozard, J. L., Metter, E. J., et al. (2000) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/55.11.m641 · Cited by 288
Bone Biology and the Clinical Implications for Osteoporosis
Downey, P. A., & Siegel, M. I. (2006) · Physical Therapy · doi:10.1093/ptj/86.1.77 · Cited by 270
Kohrt, W. M., Ehsani, A. A., & Birge, S. J. (1997) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.1997.12.8.1253 · Cited by 271
Strasser, B., Siebert, U., & Schobersberger, W. (2010) · Sports Medicine · doi:10.2165/11531380-000000000-00000 · Cited by 258
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Nowson, C., & O'Connell, S. (2015) · Nutrients · doi:10.3390/nu7085311 · Cited by 243
SIPILÄ, S., TAAFFE, D. R., CHENG, S., PUOLAKKA, J., TOIVANEN, J., & SUOMINEN, H. (2001) · Clinical Science · doi:10.1042/cs1010147 · Cited by 230
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Earles, D. R., Judge, J. O., & Gunnarsson, O. T. (2001) · Archives of Physical Medicine and Rehabilitation · doi:10.1053/apmr.2001.23838 · Cited by 226
Evidence for Resistance Training as a Treatment Therapy in Obesity
Strasser, B., & Schobersberger, W. (2011) · Journal of Obesity · doi:10.1155/2011/482564 · Cited by 220
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Kerr, D., Ackland, T., Maslen, B., Morton, A., & Prince, R. (2001) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2001.16.1.175 · Cited by 208
Progressive resistance strength training for physical disability in older people
Latham, N. K., Anderson, C. S., Bennett, D. A., & Stretton, C. (2003) · The Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002759 · Cited by 207
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Evans, W. J. (2004) · Journal of the American College of Nutrition · doi:10.1080/07315724.2004.10719430 · Cited by 204
Associations of resistance exercise with cardiovascular disease morbidity and mortality
LIU, Y., LEE, D.-C., LI, Y., ZHU, W., ZHANG, R., SUI, X., LAVIE, C. J., & BLAIR, S. N. (2019) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001822 · Cited by 187
Changes in power with resistance training in older and younger men and women
Jozsi, A. C., Campbell, W. W., Joseph, L., Davey, S. L., & Evans, W. J. (1999) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/54.11.m591 · Cited by 179
Schwingshackl, L., Dias, S., Strasser, B., & Hoffmann, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0082853 · Cited by 180
Elliott, K. J., Sale, C., & Cable, N. T. (2002) · British Journal of Sports Medicine · doi:10.1136/bjsm.36.5.340 · Cited by 180
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Willey, K. A., & Singh, M. A. F. (2003) · Diabetes Care · doi:10.2337/diacare.26.5.1580 · Cited by 165
Kemmler, W., Shojaa, M., Kohl, M., & von Stengel, S. (2020) · Calcified Tissue International · doi:10.1007/s00223-020-00744-w · Cited by 161
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EVANS, W. J., & CYR-CAMPBELL, D. (1997) · Journal of the American Dietetic Association · doi:10.1016/s0002-8223(97)00160-0 · Cited by 138
Self-citationWewege, M. A., Desai, I., Honey, C., Coorie, B., Jones, M. D., Clifford, B. K., Leake, H. B., & Hagstrom, A. D. (2022) · Sports Medicine · doi:10.1007/s40279-021-01562-2 · Cited by 155
Kenny, A. M., Boxer, R. S., Kleppinger, A., Brindisi, J., Feinn, R., & Burleson, J. A. (2010) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2010.03019.x · Cited by 125
Tartibian, B., Hajizadeh Maleki, B., Kanaley, J., & Sadeghi, K. (2011) · Nutrition & Metabolism · doi:10.1186/1743-7075-8-71 · Cited by 120
Daly, R. M., Dunstan, D. W., Owen, N., Jolley, D., Shaw, J. E., & Zimmet, P. Z. (2005) · Osteoporosis International · doi:10.1007/s00198-005-1906-4 · Cited by 118
Bouchard, D. R., Soucy, L., Sénéchal, M., Dionne, I. J., & Brochu, M. (2009) · Menopause · doi:10.1097/gme.0b013e31817dacf7 · Cited by 117
Bemben, D. A., Palmer, I. J., Bemben, M. G., & Knehans, A. W. (2010) · Bone · doi:10.1016/j.bone.2010.06.019 · Cited by 111
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CUSSLER, E. C., LOHMAN, T. G., GOING, S. B., HOUTKOOPER, L. B., METCALFE, L. L., FLINT-WAGNER, H. G., HARRIS, R. B., & TEIXEIRA, P. J. (2003) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200301000-00003 · Cited by 102
Jones, M. D., Wewege, M. A., Hackett, D. A., Keogh, J. W. L., & Hagstrom, A. D. (2021) · Sports Medicine · doi:10.1007/s40279-020-01388-4 · Cited by 96
Tager, I. B., Haight, T., Sternfeld, B., Yu, Z., & van Der Laan, M. (2004) · Epidemiology · doi:10.1097/01.ede.0000128401.55545.c6 · Cited by 84
Hagstrom, A. D., Marshall, P. W., Halaki, M., & Hackett, D. A. (2020) · Sports Medicine · doi:10.1007/s40279-019-01247-x · Cited by 78
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Hovanec, N., Sawant, A., Overend, T. J., Petrella, R. J., & Vandervoort, A. A. (2012) · Journal of Aging Research · doi:10.1155/2012/284635 · Cited by 79
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Sayers, S. P., Bean, J., Cuoco, A., LeBrasseur, N. K., Jette, A., & Fielding, R. A. (2003) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/01.phm.0000078225.71442.b6 · Cited by 79
Joseph, L. J. O., Davey, S. L., Evans, W. J., & Campbell, W. W. (1999) · Metabolism · doi:10.1016/s0026-0495(99)90162-2 · Cited by 74
Codella, R., Ialacqua, M., Terruzzi, I., & Luzi, L. (2018) · Endocrine · doi:10.1007/s12020-018-1603-7 · Cited by 72
Watson, S. L., Weeks, B. K., Weis, L. J., Harding, A. T., Horan, S. A., & Beck, B. R. (2019) · Osteoporosis International · doi:10.1007/s00198-018-04829-z · Cited by 65
Evaluation of the applicability of HRT as a preservative of muscle strength in women
Meeuwsen, I. B., Samson, M. M., & Verhaar, H. J. (2000) · Maturitas · doi:10.1016/s0378-5122(00)00132-8 · Cited by 57
Thomas, E., Gentile, A., Lakicevic, N., Moro, T., Bellafiore, M., Paoli, A., Drid, P., Palma, A., & Bianco, A. (2021) · Aging Clinical and Experimental Research · doi:10.1007/s40520-021-01853-8 · Cited by 34
Ilich, J. Z., & Brownbill, R. A. (2008) · Calcified Tissue International · doi:10.1007/s00223-008-9171-0 · Cited by 25
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Candow, D. G., & Chilibeck, P. D. (2010) · The Journal of nutrition, health and aging · doi:10.1007/s12603-009-0224-5 · Cited by 22
Metadata
- Authors
- Nelson, M. E.
- Venue
- JAMA
- Publisher
- American Medical Association (AMA)
- Published
- 1994-12-28
- Volume
- 272
- Issue
- 24
- Pages
- 1909
- ISSN
- 0002-9955 (ISSN-L)
- 0098-7484
- OpenAlex
- W2010020452
- Cited by
- 968
- References
- 3
- FWCI
- 21.39
- Type
- journal article
- Language
- en
- Open access
- closed
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