Multifunctional Wearable System that Integrates Sweat‐Based Sensing and Vital‐Sign Monitoring to Estimate Pre‐/Post‐Exercise Glucose Levels
Abstract
Wearable bioelectronic technologies have made significant progresses in personalized health management through non‐invasive monitoring of health indicators. However, current wearable systems cannot measure biochemical information and physiological signals simultaneously, which limits integrated data analysis and their widespread clinical applications. Here, an integrated multifunctional wearable health management system composed of a disposable sweat‐based glucose sensing strip and a wearable smart band is reported. The integrated system with control software electrochemically analyzes sweat glucose levels and continuously monitors vital signs (i.e., heart rate, blood oxygen saturation level, and physical activity). Different sweat collecting sites and sweat generation methods are tested in short‐ and long‐term studies with multiple human subjects by using the developed wearable system, leading to optimized protocols for health monitoring. By combining sweat glucose data and physiological monitoring data, pre‐ and post‐exercise blood glucose levels and blood glucose changes resulting from physical activities are reliably estimated, providing key information for preventing hypoglycemic shock during intense exercise. The integrated wearable system offers a novel comprehensive personalized health management strategy through combined analysis of key metabolic and physiological health indicators.
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Preliminary or small-scale correlation studies have shown promising applications for other analytes such as metabolites and certain neuroimmune biomarkers present in sweat, including a recent work showing exercise sweat glucose of three healthy subjects roughly tracks their blood glucose, making a preliminary case for semiquantitative glucose prediction.
“Preliminary or small-scale correlation studies have shown promising applications for other analytes such as metabolites and certain neuroimmune biomarkers present in sweat (3, 27–29, 36), including a recent work that shows how exercise sweat glucose of three healthy subjects roughly tracks their blood glucose, making a preliminary case for semiquantitative glucose prediction (29).”
From Regional and correlative sweat analysis using high-throughput microfluidic sensing patches toward decoding sweat (2019) · cites this paper as [28]
Cites
STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT
Martin Bland, J., & Altman, D. (1986) · The Lancet · doi:10.1016/s0140-6736(86)90837-8 · Cited by 47,965 · see citing works
Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis
Gao, W., Emaminejad, S., Nyein, H. Y. Y., Challa, S., Chen, K., Peck, A., Fahad, H. M., Ota, H., Shiraki, H., Kiriya, D., et al. (2016) · Nature · doi:10.1038/nature16521 · Cited by 5,087 · see citing works
Schwartz, G., Tee, B. C.-K., Mei, J., Appleton, A. L., Kim, D. H., Wang, H., & Bao, Z. (2013) · Nature Communications · doi:10.1038/ncomms2832 · Cited by 2,042 · see citing works
Self-citationHeart-rate Recovery Immediately After Exercise as a Predictor of Mortality
Cole, C. R., Blackstone, E. H., Pashkow, F. J., Snader, C. E., & Lauer, M. S. (1999) · New England Journal of Medicine · doi:10.1056/nejm199910283411804 · Cited by 1,935 · see citing works
Lee, H., Choi, T. K., Lee, Y. B., Cho, H. R., Ghaffari, R., Wang, L., Choi, H. J., Chung, T. D., Lu, N., Hyeon, T., et al. (2016) · Nature Nanotechnology · doi:10.1038/nnano.2016.38 · Cited by 1,802 · see citing works
Self-citationBariya, M., Nyein, H. Y. Y., & Javey, A. (2018) · Nature Electronics · doi:10.1038/s41928-018-0043-y · Cited by 1,486 · see citing works
Multifunctional wearable devices for diagnosis and therapy of movement disorders
Son, D., Lee, J., Qiao, S., Ghaffari, R., Kim, J., Lee, J. E., Song, C., Kim, S. J., Lee, D. J., Jun, S. W., et al. (2014) · Nature Nanotechnology · doi:10.1038/nnano.2014.38 · Cited by 1,462 · see citing works
Self-citationFlexible organic transistors and circuits with extreme bending stability
Sekitani, T., Zschieschang, U., Klauk, H., & Someya, T. (2010) · Nature Materials · doi:10.1038/nmat2896 · Cited by 1,253 · see citing works
Achten, J., & Jeukendrup, A. E. (2003) · Sports Medicine · doi:10.2165/00007256-200333070-00004 · Cited by 1,202 · see citing works
Lee, H., Song, C., Hong, Y. S., Kim, M., Cho, H. R., Kang, T., Shin, K., Choi, S. H., Hyeon, T., & Kim, D.-H. (2017) · Science Advances · doi:10.1126/sciadv.1601314 · Cited by 1,118 · see citing works
Self-citationRecent Advances in Flexible and Stretchable Bio‐Electronic Devices Integrated with Nanomaterials
Choi, S., Lee, H., Ghaffari, R., Hyeon, T., & Kim, D. (2016) · Advanced Materials · doi:10.1002/adma.201504150 · Cited by 1,104 · see citing works
Self-citationOrganic Nonvolatile Memory Transistors for Flexible Sensor Arrays
Sekitani, T., Yokota, T., Zschieschang, U., Klauk, H., Bauer, S., Takeuchi, K., Takamiya, M., Sakurai, T., & Someya, T. (2009) · Science · doi:10.1126/science.1179963 · Cited by 962 · see citing works
Wearable smart sensor systems integrated on soft contact lenses for wireless ocular diagnostics
Kim, J., Kim, M., Lee, M.-S., Kim, K., Ji, S., Kim, Y.-T., Park, J., Na, K., Bae, K.-H., Kyun Kim, H., et al. (2017) · Nature Communications · doi:10.1038/ncomms14997 · Cited by 951 · see citing works
Self-citationImani, S., Bandodkar, A. J., Mohan, A. M. V., Kumar, R., Yu, S., Wang, J., & Mercier, P. P. (2016) · Nature Communications · doi:10.1038/ncomms11650 · Cited by 861 · see citing works
Enzyme‐Based Glucose Sensor: From Invasive to Wearable Device
Lee, H., Hong, Y. J., Baik, S., Hyeon, T., & Kim, D. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201701150 · Cited by 778 · see citing works
Self-citationSonner, Z., Wilder, E., Heikenfeld, J., Kasting, G., Beyette, F., Swaile, D., Sherman, F., Joyce, J., Hagen, J., Kelley-Loughnane, N., et al. (2015) · Biomicrofluidics · doi:10.1063/1.4921039 · Cited by 724 · see citing works
Nishime, E. O. (2000) · JAMA · doi:10.1001/jama.284.11.1392 · Cited by 713 · see citing works
Soft, smart contact lenses with integrations of wireless circuits, glucose sensors, and displays
Park, J., Kim, J., Kim, S.-Y., Cheong, W. H., Jang, J., Park, Y.-G., Na, K., Kim, Y.-T., Heo, J. H., Lee, C. Y., et al. (2018) · Science Advances · doi:10.1126/sciadv.aap9841 · Cited by 671 · see citing works
Self-citationNyein, H. Y. Y., Gao, W., Shahpar, Z., Emaminejad, S., Challa, S., Chen, K., Fahad, H. M., Tai, L.-C., Ota, H., Davis, R. W., et al. (2016) · ACS Nano · doi:10.1021/acsnano.6b04005 · Cited by 669 · see citing works
Correlation Between Sweat Glucose and Blood Glucose in Subjects with Diabetes
Moyer, J., Wilson, D., Finkelshtein, I., Wong, B., & Potts, R. (2012) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2011.0262 · Cited by 570 · see citing works
Chen, L. Y., Tee, B. C. K., Chortos, A., Schwartz, G., Tse, V., Lipomi, D. J., Wong, H. ‐. P., McConnell, M. V., & Bao, Z. (2014) · Nature Communications · doi:10.1038/ncomms6028 · Cited by 541 · see citing works
Skin-like biosensor system via electrochemical channels for noninvasive blood glucose monitoring
Chen, Y., Lu, S., Zhang, S., Li, Y., Qu, Z., Chen, Y., Lu, B., Wang, X., & Feng, X. (2017) · Science Advances · doi:10.1126/sciadv.1701629 · Cited by 470 · see citing works
Contact Lens Sensors in Ocular Diagnostics
Farandos, N. M., Yetisen, A. K., Monteiro, M. J., Lowe, C. R., & Yun, S. H. (2015) · Advanced Healthcare Materials · doi:10.1002/adhm.201400504 · Cited by 466 · see citing works
Abellán-Llobregat, A., Jeerapan, I., Bandodkar, A., Vidal, L., Canals, A., Wang, J., & Morallón, E. (2017) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2017.01.058 · Cited by 348 · see citing works
Choi, J., Kang, D., Han, S., Kim, S. B., & Rogers, J. A. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201601355 · Cited by 317 · see citing works
Jensen, M. T., Suadicani, P., Hein, H. O., & Gyntelberg, F. (2013) · Heart · doi:10.1136/heartjnl-2012-303375 · Cited by 297 · see citing works
Non‐invasive Analyte Access and Sensing through Eccrine Sweat: Challenges and Outlook circa 2016
Heikenfeld, J. (2016) · Electroanalysis · doi:10.1002/elan.201600018 · Cited by 294 · see citing works
Wearable Wireless Tyrosinase Bandage and Microneedle Sensors: Toward Melanoma Screening
Ciui, B., Martín, A., Mishra, R. K., Brunetti, B., Nakagawa, T., Dawkins, T. J., Lyu, M., Cristea, C., Săndulescu, R., & Wang, J. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201701264 · Cited by 262 · see citing works
Electromechanical cardioplasty using a wrapped elasto-conductive epicardial mesh
Park, J., Choi, S., Janardhan, A. H., Lee, S.-Y., Raut, S. S., Soares, J., Shin, K., Yang, S., Lee, C., Kang, K., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aad8568 · Cited by 253 · see citing works
Self-citationCan continuous glucose monitoring be used for the treatment of diabetes?
Reach, G., & Wilson, G. S. (1992) · Analytical Chemistry · doi:10.1021/ac00030a001 · Cited by 239 · see citing works
Soft Thermal Sensor with Mechanical Adaptability
Yang, H., Qi, D., Liu, Z., Chandran, B. K., Wang, T., Yu, J., & Chen, X. (2016) · Advanced Materials · doi:10.1002/adma.201602994 · Cited by 226 · see citing works
Guelfi, K. J., Jones, T. W., & Fournier, P. A. (2005) · Diabetes Care · doi:10.2337/diacare.28.6.1289 · Cited by 221 · see citing works
Lee, H., Lee, Y., Song, C., Cho, H. R., Ghaffari, R., Choi, T. K., Kim, K. H., Lee, Y. B., Ling, D., Lee, H., et al. (2015) · Nature Communications · doi:10.1038/ncomms10059 · Cited by 190 · see citing works
Self-citationCheng, Y. J., Lauer, M. S., Earnest, C. P., Church, T. S., Kampert, J. B., Gibbons, L. W., & Blair, S. N. (2003) · Diabetes Care · doi:10.2337/diacare.26.7.2052 · Cited by 189 · see citing works
Choi, M. K., Park, I., Kim, D. C., Joh, E., Park, O. K., Kim, J., Kim, M., Choi, C., Yang, J., Cho, K. W., et al. (2015) · Advanced Functional Materials · doi:10.1002/adfm.201502956 · Cited by 186 · see citing works
Self-citationWearable Force Touch Sensor Array Using a Flexible and Transparent Electrode
Song, J., Son, D., Kim, J., Yoo, Y. J., Lee, G. J., Wang, L., Choi, M. K., Yang, J., Lee, M., Do, K., et al. (2016) · Advanced Functional Materials · doi:10.1002/adfm.201605286 · Cited by 184 · see citing works
Self-citationA wearable multiplexed silicon nonvolatile memory array using nanocrystal charge confinement
Kim, J., Son, D., Lee, M., Song, C., Song, J.-K., Koo, J. H., Lee, D. J., Shim, H. J., Kim, J. H., Lee, M., et al. (2016) · Science Advances · doi:10.1126/sciadv.1501101 · Cited by 164 · see citing works
Self-citationHong, S., Lee, J., Do, K., Lee, M., Kim, J. H., Lee, S., & Kim, D. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201704353 · Cited by 161 · see citing works
Self-citationChoi, J., Xue, Y., Xia, W. J., Ray, T. R., Reeder, J. T., Bandodkar, A. J., Kang, D., Xu, S., Huang, Y. Y., & Rogers, J. A. (2017) · Lab on a Chip · doi:10.1039/c7lc00525c · Cited by 147 · see citing works
The quest for miniaturized soft bioelectronic devices
Kim, J., Ghaffari, R., & Kim, D. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-017-0049 · Cited by 132 · see citing works
Self-citationWearable Sensing Systems with Mechanically Soft Assemblies of Nanoscale Materials
Lee, Y., Kim, J., Joo, H., Raj, M. S., Ghaffari, R., & Kim, D. (2017) · Advanced Materials Technologies · doi:10.1002/admt.201700053 · Cited by 115 · see citing works
Self-citationChoudhary, T., Rajamanickam, G. P., & Dendukuri, D. (2015) · Lab on a Chip · doi:10.1039/c5lc00041f · Cited by 96 · see citing works
Nanomaterials for bioelectronics and integrated medical systems
Lee, Y., Kim, J., Koo, J. H., Kim, T., & Kim, D. (2017) · Korean Journal of Chemical Engineering · doi:10.1007/s11814-017-0236-5 · Cited by 72 · see citing works
Self-citationExercise Strategies for Hypoglycemia Prevention in Individuals With Type 1 Diabetes
Yardley, J. E., & Sigal, R. J. (2015) · Diabetes Spectrum · doi:10.2337/diaspect.28.1.32 · Cited by 65 · see citing works
Exercise, Hypoglycemia, and Type 1 Diabetes
Basu, R., Johnson, M. L., Kudva, Y. C., & Basu, A. (2014) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2014.0097 · Cited by 56 · see citing works
A comparison of energy expenditure during rowing and cycling ergometry
Hagerman, F. C., LAWRENCE, R. A., & MANSFIELD, M. C. (1988) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-198810000-00009 · Cited by 49 · see citing works
The accuracy of the ACSM cycle ergometry equation
Lang, P., Latin, R. W., Berg, K. E., & Mellion, M. B. (1992) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-199202000-00019 · Cited by 44 · see citing works
The effect of rope skipping rate on energy expenditure of males and females
TOWN, G. P., Sol, N., & Sinning, W. E. (1980) · Medicine & Science in Sports & Exercise · doi:10.1249/00005768-198024000-00012 · Cited by 39 · see citing works
Feasibility of a Patient-Centered, Smartphone-Based, Diabetes Care System: A Pilot Study
Kim, E. K., Kwak, S. H., Baek, S., Lee, S. L., Jang, H. C., Park, K. S., & Cho, Y. M. (2016) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2016.40.3.192 · Cited by 35 · see citing works
Managing diabetes through the skin
Guy, R. H. (2016) · Nature Nanotechnology · doi:10.1038/nnano.2016.53 · Cited by 30 · see citing works
The energy cost of rope skipping.
Jetté, M., Mongeon, J., & Routhier, R. (1979) · PubMed · Cited by 23 · see citing works
Uemura, M., Yano, Y., Suzuki, T., Yasuma, T., Sato, T., Morimoto, A., Hosoya, S., Suminaka, C., Nakajima, H., Gabazza, E. C., et al. (2017) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2017.41.4.265 · Cited by 7 · see citing works
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Bio-Integrated Wearable Systems: A Comprehensive Review
Ray, T. R., Choi, J., Bandodkar, A. J., Krishnan, S., Gutruf, P., Tian, L., Ghaffari, R., & Rogers, J. A. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00573 · Cited by 1,350 · see citing works
Wearable and flexible electrochemical sensors for sweat analysis: a review
Gao, F., Liu, C., Zhang, L., Liu, T., Wang, Z., Song, Z., Cai, H., Fang, Z., Chen, J., Wang, J., et al. (2022) · Microsystems & Nanoengineering · doi:10.1038/s41378-022-00443-6 · Cited by 813 · see citing works
Skin-Interfaced Wearable Sweat Sensors for Precision Medicine
Min, J., Tu, J., Xu, C., Lukas, H., Shin, S., Yang, Y., Solomon, S. A., Mukasa, D., & Gao, W. F. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.2c00823 · Cited by 728 · see citing works
An epidermal patch for the simultaneous monitoring of haemodynamic and metabolic biomarkers
Sempionatto, J. R., Lin, M., Yin, L., De la paz, E., Pei, K., Sonsa-ard, T., de Loyola Silva, A. N., Khorshed, A. A., Zhang, F., Tostado, N., et al. (2021) · Nature Biomedical Engineering · doi:10.1038/s41551-021-00685-1 · Cited by 658 · see citing works
Hong, Y. J., Jeong, H., Cho, K. W., Lu, N., & Kim, D. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201808247 · Cited by 559 · see citing works
Self-citationEmerging Technologies of Flexible Pressure Sensors: Materials, Modeling, Devices, and Manufacturing
Huang, Y., Fan, X., Chen, S., & Zhao, N. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201808509 · Cited by 543 · see citing works
Wireless smart contact lens for diabetic diagnosis and therapy
Keum, D. H., Kim, S.-K., Koo, J., Lee, G.-H., Jeon, C., Mok, J. W., Mun, B. H., Lee, K. J., Kamrani, E., Joo, C.-K., et al. (2020) · Science Advances · doi:10.1126/sciadv.aba3252 · Cited by 483 · see citing works
Electrochemical non-enzymatic glucose sensors: recent progress and perspectives
Wei, M., Qiao, Y., Zhao, H., Liang, J., Li, T., Luo, Y., Lu, S., Shi, X., Lu, W., & Sun, X. (2020) · Chemical Communications · doi:10.1039/d0cc05650b · Cited by 469 · see citing works
Material‐Based Approaches for the Fabrication of Stretchable Electronics
Kim, D. C., Shim, H. J., Lee, W., Koo, J. H., & Kim, D. (2019) · Advanced Materials · doi:10.1002/adma.201902743 · Cited by 440 · see citing works
Self-citationWearable Electrochemical Glucose Sensors in Diabetes Management: A Comprehensive Review
Saha, T., Del Caño, R., Mahato, K., De la Paz, E., Chen, C., Ding, S., Yin, L., & Wang, J. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.3c00078 · Cited by 442 · see citing works
Hybrid multimodal wearable sensors for comprehensive health monitoring
Mahato, K., Saha, T., Ding, S., Sandhu, S. S., Chang, A., & Wang, J. (2024) · Nature Electronics · doi:10.1038/s41928-024-01247-4 · Cited by 435 · see citing works
Nyein, H. Y. Y., Bariya, M., Kivimäki, L., Uusitalo, S., Liaw, T. S., Jansson, E., Ahn, C. H., Hangasky, J. A., Zhao, J., Lin, Y., et al. (2019) · Science Advances · doi:10.1126/sciadv.aaw9906 · Cited by 388 · see citing works
The Era of Digital Health: A Review of Portable and Wearable Affinity Biosensors
Tu, J., Torrente-Rodríguez, R. M., Wang, M., & Gao, W. F. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201906713 · Cited by 359 · see citing works
Flexible Electrochemical Bioelectronics: The Rise of In Situ Bioanalysis
Yu, Y., Nyein, H. Y. Y., Gao, W. F., & Javey, A. (2019) · Advanced Materials · doi:10.1002/adma.201902083 · Cited by 347 · see citing works
Wang, Y., Zhao, C., Wang, J., Luo, X., Xie, L., Zhan, S., Kim, J., Wang, X., Liu, X., & Ying, Y. B. (2021) · Science Advances · doi:10.1126/sciadv.abe4553 · Cited by 345 · see citing works
Self-citationAdeel, M., Rahman, M. M., Caligiuri, I., Canzonieri, V., Rizzolio, F., & Daniele, S. (2020) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2020.112331 · Cited by 325 · see citing works
A Fully Integrated and Self-Powered Smartwatch for Continuous Sweat Glucose Monitoring
Zhao, J., Lin, Y., Wu, J., Nyein, H. Y. Y., Bariya, M., Tai, L., Chao, M., Ji, W., Zhang, G. B., Fan, Z., et al. (2019) · ACS Sensors · doi:10.1021/acssensors.9b00891 · Cited by 283 · see citing works
Internet of things (IoT) in nano-integrated wearable biosensor devices for healthcare applications
Verma, D., Singh, K. R., Yadav, A. K., Nayak, V., Singh, J., Solanki, P. R., & Singh, R. P. (2022) · Biosensors and Bioelectronics X · doi:10.1016/j.biosx.2022.100153 · Cited by 274 · see citing works
Soft Bioelectronics Based on Nanomaterials
Cho, K. W., Sunwoo, S., Hong, Y. J., Koo, J. H., Kim, J. H., Baik, S., Hyeon, T., & Kim, D. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00531 · Cited by 247 · see citing works
Self-citationAdvanced electronic skin devices for healthcare applications
Ma, Z., Li, S., Wang, H., Cheng, W. M., Li, Y., Pan, L., & Shi, Y. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb02862a · Cited by 237 · see citing works
Wearable and Mobile Sensors for Personalized Nutrition
Sempionatto, J. R., Montiel, V. R.-V., Vargas, E., Teymourian, H., & Wang, J. (2021) · ACS Sensors · doi:10.1021/acssensors.1c00553 · Cited by 237 · see citing works
Wearable hydrogel patch with noninvasive, electrochemical glucose sensor for natural sweat detection
Lin, P.-H., Sheu, S.-C., Chen, C., Huang, S., & Li, B. (2022) · Talanta · doi:10.1016/j.talanta.2021.123187 · Cited by 232 · see citing works
Kwon, K., Kim, J. U., Deng, Y., Krishnan, S. R., Choi, J., Jang, H., Lee, K., Su, C.-J., Yoo, I., Wu, Y., et al. (2021) · Nature Electronics · doi:10.1038/s41928-021-00556-2 · Cited by 230 · see citing works
Self-citationA highly integrated sensing paper for wearable electrochemical sweat analysis
Li, M., Wang, L., Liu, R., Li, J., Zhang, Q., Shi, G., Li, Y., Hou, C., & Wang, H. (2020) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2020.112828 · Cited by 220 · see citing works
Integrated Smart Janus Textile Bands for Self-Pumping Sweat Sampling and Analysis
He, X., Yang, S., Pei, Q., Song, Y., Liu, C., Xu, T., & Zhang, X. (2020) · ACS Sensors · doi:10.1021/acssensors.0c00563 · Cited by 186 · see citing works
Liu, G., Lv, Z., Batool, S. A., Li, M.-Z., Zhao, P., Guo, L., Wang, Y., Zhou, Y., & Han, S. (2023) · Small · doi:10.1002/smll.202207879 · Cited by 191 · see citing works
Flexible Plasmonic Biosensors for Healthcare Monitoring: Progress and Prospects
Song, L., Chen, J., Xu, B. B., & Huang, Y. (2021) · ACS Nano · doi:10.1021/acsnano.1c07176 · Cited by 186 · see citing works
A mountable toilet system for personalized health monitoring via the analysis of excreta
Park, S.-M., Won, D. D., Lee, B. J., Escobedo, D., Esteva, A., Aalipour, A., Ge, T. J., Kim, J. H., Suh, S., Choi, E. H., et al. (2020) · Nature Biomedical Engineering · doi:10.1038/s41551-020-0534-9 · Cited by 175 · see citing works
Self-citationWearable flexible microfluidic sensing technologies
Chen, S., Zheng, Q., Niu, Y., Yeo, J. C., Liu, Y., Qi, J., Fan, S., Liu, X., Lee, J. Y., & Lim, C. T. (2023) · Nature Reviews Bioengineering · doi:10.1038/s44222-023-00094-w · Cited by 189 · see citing works
Soft Wearable Systems for Colorimetric and Electrochemical Analysis of Biofluids
Ghaffari, R., Choi, J., Raj, M. S., Chen, S., Lee, S. P., Reeder, J. T., Aranyosi, A. J., Leech, A., Li, W., Schon, S., et al. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201907269 · Cited by 173 · see citing works
Transdermal Electrochemical Monitoring of Glucose via High‐Density Silicon Microneedle Array Patch
Dervisevic, M., Alba, M., Yan, L., Şenel, M., Gengenbach, T. R., Prieto‐Simón, B., & Voelcker, N. H. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202009850 · Cited by 173 · see citing works
Zhao, T., Fu, Y., Sun, C., Zhao, X., Jiao, C., Du, A., Wang, Q., Mao, Y., & Liu, B. (2022) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2022.114115 · Cited by 173 · see citing works
Wen, F., He, T., Liu, H., Chen, H., Zhang, T., & Lee, C. (2020) · Nano Energy · doi:10.1016/j.nanoen.2020.105155 · Cited by 160 · see citing works
Wearable multiplexed biosensor system toward continuous monitoring of metabolites
Yokus, M. A., Songkakul, T., Pozdin, V. A., Bozkurt, A., & Daniele, M. A. (2020) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2020.112038 · Cited by 153 · see citing works
Flexible Hybrid Sensor Systems with Feedback Functions
Xu, K., Lu, Y., & Takei, K. (2020) · Advanced Functional Materials · doi:10.1002/adfm.202007436 · Cited by 152 · see citing works
Printing Flexible and Hybrid Electronics for Human Skin and Eye‐Interfaced Health Monitoring Systems
Kim, K., Kim, B., & Lee, C. H. (2019) · Advanced Materials · doi:10.1002/adma.201902051 · Cited by 146 · see citing works
Integrated Devices for Non‐Invasive Diagnostics
Ates, H. C., Brunauer, A., von Stetten, F., Urban, G. A., Güder, F., Merkoçi, A., Früh, S. M., & Dincer, C. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202010388 · Cited by 149 · see citing works
Ma, C., Shang, X., Sun, M., Bo, X., Bai, J., Du, Y., & Zhou, M. (2025) · ACS Sensors · doi:10.1021/acssensors.4c03396 · Cited by 147 · see citing works
Legner, C. M., Kalwa, U., Patel, V., Chesmore, A., & Pandey, S. (2019) · Sensors and Actuators A Physical · doi:10.1016/j.sna.2019.07.020 · Cited by 141 · see citing works
A wearable freestanding electrochemical sensing system
Zhao, Y., Wang, B., Hojaiji, H., Wang, Z., Lin, S., Yeung, C. J., Lin, H., Nguyen, P., Chiu, K., Salahi, K., et al. (2020) · Science Advances · doi:10.1126/sciadv.aaz0007 · Cited by 142 · see citing works
da Silva, R. R., Raymundo‐Pereira, P. A., de Campos, A. M., Wilson, D., Otoni, C. G., Barud, H. D. S., Costa, C. A. R., Domeneguetti, R. R., Balogh, D. T., Ribeiro, S. J. L., et al. (2020) · Talanta · doi:10.1016/j.talanta.2020.121153 · Cited by 139 · see citing works
Advances in Sweat Wearables: Sample Extraction, Real-Time Biosensing, and Flexible Platforms
Qiao, L., Benzigar, M. R., Subramony, J. A., Lovell, N. H., & Liu, G. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c07614 · Cited by 137 · see citing works
Organic Bioelectronic Devices for Metabolite Sensing
Koklu, A., Ohayon, D., Wustoni, S., Druet, V., Saleh, A., & Inal, S. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00395 · Cited by 134 · see citing works
Nanocellulose in biomedical and biosensing applications: A review
Subhedar, A. R., Bhadauria, S. S., Ahankari, S. S., & Kargarzadeh, H. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.10.217 · Cited by 135 · see citing works
Recent Advances in Electrochemical Sensors for Wearable Sweat Monitoring: A Review
Yeung, K. K., Huang, T., Hua, Y., Zhang, K., Yuen, M. M. F., & Gao, Z. (2021) · IEEE Sensors Journal · doi:10.1109/jsen.2021.3074311 · Cited by 128 · see citing works
Khor, S. M., Choi, J., Won, P., & Ko, S. H. (2022) · Nanomaterials · doi:10.3390/nano12020221 · Cited by 128 · see citing works
Facile Fabrication of Flexible Pressure Sensor with Programmable Lattice Structure
Yin, Y. M., Li, H. Y., Jin, X., Zhang, C., Liang, F., Li, X., Jiang, Y., Cao, J., Han, F., Mao, J. N., et al. (2021) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c21407 · Cited by 127 · see citing works
Lorestani, F., Zhang, X., Abdullah, A. M., Xin, X., Liu, Y., Rahman, M. M., Biswas, M. A. S., Li, B., Dutta, A., Niu, Z., et al. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202306117 · Cited by 125 · see citing works
Bio-inspired flexible electronics for smart E-skin
Nie, B., Liu, S., Qu, Q., Zhang, Y., Zhao, M., & Liu, J. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.06.018 · Cited by 122 · see citing works
Organic Electrochemical Transistors for Biomarker Detections
Liu, H., Song, J., Zhao, Z., Zhao, S., Tian, Z., & Yan, F. (2024) · Advanced Science · doi:10.1002/advs.202305347 · Cited by 121 · see citing works
Tough Adhesion of Nucleobase‐Tackifed Gels in Diverse Solvents
Liu, X., Zhang, Q., Duan, L., & Gao, G. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201900450 · Cited by 119 · see citing works
Wireless Power Transfer and Telemetry for Implantable Bioelectronics
Yoo, S., Lee, J. H., Joo, H., Sunwoo, S., Kim, S., & Kim, D. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202100614 · Cited by 116 · see citing works
Self-citationModular and Reconfigurable Wireless E‐Tattoos for Personalized Sensing
Jeong, H., Wang, L., Ha, T., Mitbander, R., Yang, X., Dai, Z., Qiao, S., Shen, L., Sun, N., & Lu, N. (2019) · Advanced Materials Technologies · doi:10.1002/admt.201900117 · Cited by 111 · see citing works
Zhang, K., Zhang, J., Wang, F., & Kong, D. (2021) · ACS Sensors · doi:10.1021/acssensors.1c00316 · Cited by 109 · see citing works
Park, H., Song, C., Jin, S. W., Lee, H.-C., Keum, K., Lee, Y. H., Lee, G., Jeong, Y. R., & Ha, J. S. (2021) · Nano Energy · doi:10.1016/j.nanoen.2021.105837 · Cited by 109 · see citing works
Self-citationRemote Healthcare for Elderly People Using Wearables: A Review
Olmedo-Aguirre, J. O., Reyes-Campos, J., Alor‐Hernández, G., Machorro-Cano, I., Rodríguez-Mazahua, L., & Sánchez-Cervantes, J. L. (2022) · Biosensors · doi:10.3390/bios12020073 · Cited by 104 · see citing works
Material Design and Fabrication Strategies for Stretchable Metallic Nanocomposites
Joo, H., Jung, D., Sunwoo, S., Koo, J. H., & Kim, D. (2020) · Small · doi:10.1002/smll.201906270 · Cited by 101 · see citing works
Self-citationWearable Biofuel Cells: Advances from Fabrication to Application
Wu, H., Zhang, Y., Kjøniksen, A., Zhou, X., & Zhou, X. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202103976 · Cited by 104 · see citing works
Recent advances in flexible and wearable sensors for monitoring chemical molecules
Zhao, H., Su, R., Teng, L., Tian, Q., Han, F., Li, H., Cao, Z., Xie, R., Li, G., Liu, X., et al. (2021) · Nanoscale · doi:10.1039/d1nr06244a · Cited by 101 · see citing works
Simple, Skin-Attachable, and Multifunctional Colorimetric Sweat Sensor
Yue, X., Xu, F., Zhang, L., Ren, G., Sheng, H., Wang, J., Wang, K., Yu, L., Wang, J., Li, G., et al. (2022) · ACS Sensors · doi:10.1021/acssensors.2c00581 · Cited by 96 · see citing works
Wang, L., Jiang, L., Li, Q., Li, L., He, E., Jiao, Y., Ye, T., & Zhang, Y. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202200922 · Cited by 96 · see citing works
Chun, K., Seo, S., & Han, C. (2022) · Advanced Materials · doi:10.1002/adma.202110082 · Cited by 97 · see citing works
He, T., & Lee, C. (2021) · IEEE Open Journal of Circuits and Systems · doi:10.1109/ojcas.2021.3123272 · Cited by 97 · see citing works
Zhao, H., Zhang, X., Qin, Y., Xia, Y., Xu, X. S., Sun, X., Yu, D., Mugo, S. M., Wang, D., & Zhang, Q. M. (2022) · Advanced Functional Materials · doi:10.1002/adfm.202212083 · Cited by 93 · see citing works
Microfluidic integration for electrochemical biosensor applications
Schmidt-Speicher, L. M., & Länge, K. (2021) · Current Opinion in Electrochemistry · doi:10.1016/j.coelec.2021.100755 · Cited by 89 · see citing works
Wearable sweat sensing for prolonged, semicontinuous, and nonobtrusive health monitoring
Moonen, E. J. M., Haakma, J. R., Peri, E., Pelssers, E., Mischi, M., & den Toonder, J. M. J. (2020) · VIEW · doi:10.1002/viw.20200077 · Cited by 86 · see citing works
Intelligent wearable devices based on nanomaterials and nanostructures for healthcare
Xie, L., Zhang, Z., Wu, Q., Gao, Z., Mi, G., Wang, R., Sun, H., Zhao, Y., & Du, Y. (2022) · Nanoscale · doi:10.1039/d2nr04551f · Cited by 87 · see citing works
Materials engineering, processing, and device application of hydrogel nanocomposites
Cha, G. D., Lee, W. H., Lim, C., Choi, M. K., & Kim, D. (2020) · Nanoscale · doi:10.1039/d0nr01456g · Cited by 83 · see citing works
Self-citationLee, W., Jeong, S., Lim, Y., Lee, H., Kang, J., Lee, H., Lee, I., Han, H., Kobayashi, S., Tanaka, M., et al. (2021) · Science Advances · doi:10.1126/sciadv.abi6290 · Cited by 82 · see citing works
Self-citationPei, X., Sun, M., Wang, J., Bai, J., Bo, X., & Zhou, M. (2022) · Small · doi:10.1002/smll.202205061 · Cited by 80 · see citing works
Niu, J., Lin, S., Chen, D., Wang, Z., Cao, C., Gao, A., Cui, S., Liu, Y., Hong, Y., Zhi, X., et al. (2023) · Small · doi:10.1002/smll.202306769 · Cited by 81 · see citing works
Self-citationAssalve, G., Lunetti, P., di Cagno, A., Luca, E. W. D., Aldegheri, S., Zara, V., & Ferramosca, A. (2024) · Biosensors · doi:10.3390/bios14120574 · Cited by 85 · see citing works
Recent Advances in Flexible Field‐Effect Transistors toward Wearable Sensors
Li, M.-Z., Han, S., & Zhou, Y. (2020) · Advanced Intelligent Systems · doi:10.1002/aisy.202000113 · Cited by 76 · see citing works
Wearable microfluidic-based e-skin sweat sensors
Tabasum, H., Gill, N. K., Mishra, R., & Lone, S. (2022) · RSC Advances · doi:10.1039/d1ra07888g · Cited by 77 · see citing works
Core–Sheath Stretchable Conductive Fibers for Safe Underwater Wearable Electronics
Zhang, Y., Zhang, W., Guo, Y., Tan, Q., Zhao, Y., Qiu, J., Qi, S., Du, X., Chen, T., & Liu, N. (2019) · Advanced Materials Technologies · doi:10.1002/admt.201900880 · Cited by 72 · see citing works
Mo, L., Ma, X., Fan, L., Xin, J. H., & Yu, H. (2022) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.140473 · Cited by 72 · see citing works
Yang, Y., Sheng, C., Dong, F., & Liu, S. (2024) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2024.116280 · Cited by 70 · see citing works
Ethical Considerations of Wearable Technologies in Human Research
Tu, J., & Gao, W. F. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202100127 · Cited by 71 · see citing works
Blood Glucose Level Regression for Smartphone PPG Signals Using Machine Learning
Islam, T. T., Ahmed, M. S., Hassanuzzaman, M., Amir, S. A. B., & Rahman, T. (2021) · Applied Sciences · doi:10.3390/app11020618 · Cited by 72 · see citing works
Materials and devices for flexible and stretchable photodetectors and light-emitting diodes
Song, J., Kim, M. S., Yoo, S., Koo, J. H., & Kim, D. (2021) · Nano Research · doi:10.1007/s12274-021-3447-3 · Cited by 68 · see citing works
Self-citationFlexible, wearable biosensors for digital health
Zhu, P., Peng, H., & Rwei, A. Y. (2022) · Medicine in Novel Technology and Devices · doi:10.1016/j.medntd.2022.100118 · Cited by 68 · see citing works
Demuru, S., Huang, C.-H., Parvez, K., Worsley, R. E., Mattana, G., Piro, B., Noël, V., Casiraghi, C., & Briand, D. (2022) · ACS Applied Nano Materials · doi:10.1021/acsanm.1c04434 · Cited by 66 · see citing works
Stretchable conductive nanocomposites and their applications in wearable devices
Park, C., Kim, M. S., Kim, H. H., Sunwoo, S., Jung, D. J., Choi, M. K., & Kim, D. (2022) · Applied Physics Reviews · doi:10.1063/5.0093261 · Cited by 68 · see citing works
Self-citationAlhaddad, A. Y., Aly, H., Gad, H., Al-Ali, A. K., Sadasivuni, K. K., Cabibihan, J., & Malik, R. A. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.876672 · Cited by 71 · see citing works
Sun, J., Wu, X., Xiao, J., Zhang, Y., Ding, J., Jiang, J., Chen, Z., Liu, X., Wei, D., Zhou, L., et al. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c20057 · Cited by 67 · see citing works
Wearable chem-biosensing devices: from basic research to commercial market
Yang, B., Jiang, X., Fang, X., & Kong, J. (2021) · Lab on a Chip · doi:10.1039/d1lc00438g · Cited by 64 · see citing works
Materials, Devices, and Applications for Wearable and Implantable Electronics
Han, W. B., Ko, G., Jang, T., & Hwang, S. (2021) · ACS Applied Electronic Materials · doi:10.1021/acsaelm.0c00724 · Cited by 63 · see citing works
Qureshi, A., & Niazi, J. H. (2023) · Materials Horizons · doi:10.1039/d2mh01517j · Cited by 62 · see citing works
Soft conductive nanocomposites for recording biosignals on skin
Nam, S., Park, C., Sunwoo, S., Kim, M., Lee, H., Lee, M., & Kim, D. (2023) · Soft Science · doi:10.20517/ss.2023.19 · Cited by 63 · see citing works
Self-citationPaper-based sustainable biosensors
Kumar, A., & Maiti, P. (2024) · Materials Advances · doi:10.1039/d3ma01019h · Cited by 62 · see citing works
Cheng, X., Wang, B., Zhao, Y., Hojaiji, H., Lin, S., Shih, R. M., Lin, H., Tamayosa, S., Ham, B., Stout, P., et al. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201908507 · Cited by 61 · see citing works
Skin-interfaced electronics: A promising and intelligent paradigm for personalized healthcare
Zhu, Y., Li, J., Kim, J., Li, S., Zhao, Y., Bahari, J., Eliahoo, P., Li, G., Kawakita, S., Haghniaz, R., et al. (2023) · Biomaterials · doi:10.1016/j.biomaterials.2023.122075 · Cited by 63 · see citing works
Self-citationClinical applications of smart wearable sensors
Tao, Q., Liu, S., Zhang, J., Jiang, J., Jin, Z., Huang, Y., Liu, X., Lin, S., Zeng, X., Li, X., et al. (2023) · iScience · doi:10.1016/j.isci.2023.107485 · Cited by 63 · see citing works
TENG-based self-powered device- the heart of life
Wang, Y., Zhang, J., Jia, X., Chen, M., Wang, H., Ji, G., Zhou, H., Fang, Z., & Gao, Z. (2023) · Nano Energy · doi:10.1016/j.nanoen.2023.109080 · Cited by 63 · see citing works
Electrochemical sensing fibers for wearable health monitoring devices
Tian, H., Ma, J., Li, Y., Xiao, X., Zhang, M., Wang, H., Zhu, N., Hou, C., & Ulstrup, J. (2023) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2023.115890 · Cited by 62 · see citing works
Yokus, M. A., & Daniele, M. A.-A. (2021) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2021.113249 · Cited by 60 · see citing works
Tao, L., Xu, Y., Zhao, A., He, W., & Xiao, F. (2022) · Analytica Chimica Acta · doi:10.1016/j.aca.2022.339461 · Cited by 59 · see citing works
Microfluidic wearable electrochemical sweat sensors for health monitoring
Balaji, R., & Liao, Y. (2022) · Biomicrofluidics · doi:10.1063/5.0116648 · Cited by 60 · see citing works
Kang, M. S., Qu, R., Sun, X., Yan, Y., Ma, Z., Wang, H., Yan, K., Zhang, W., & Deng, Y. (2023) · Advanced Materials · doi:10.1002/adma.202309629 · Cited by 57 · see citing works
Koo, J. H., Song, J., Yoo, S., Sunwoo, S., Son, D., & Kim, D. (2020) · Advanced Materials Technologies · doi:10.1002/admt.202000407 · Cited by 58 · see citing works
Self-citation
- Authors
- Hong, Y. J., Lee, H., Kim, J., Lee, M., Choi, H. J., Hyeon, T., & Kim, D.
- Affiliations
- Seoul National University (KR)
- Corresponding author
- Kim, Dae‐Hyeong
- ORCID
- Venue
- Advanced Functional Materials
- Publisher
- Wiley
- Published
- 2018-10-10
- Volume
- 28
- Issue
- 47
- ISSN
- 1616-301X (ISSN-L)
- 1616-3028
- OpenAlex
- W2895941015
- Cited by
- 229
- References
- 52
- Citations by year
- 2026: 9 · 2025: 23 · 2024: 30 · 2023: 34 · 2022: 37 · 2021: 49 · 2020: 27 · 2019: 19 · 2018: 1
- FWCI
- 9.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Advanced Functional Materials (publishedVersion)
- Seoul National University Open Repository (Seoul National University) (submittedVersion)
- Funders
- National Research Foundation of Korea (NRF‐2017H1A2A1043976)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Sensor and Energy Harvesting Materials
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Keywords
- wearable sensors, vital signs monitoring, exercise-induced hypoglycemia, blood glucose estimation, smart band, heart rate monitoring, oxygen saturation, physical activity monitoring, personalized health management, non-invasive health monitoring
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