Cited by 283Health Policy Implementation ScienceHealth Sciences Research and EducationSchool Health and Nursing Education

Addressing Core Challenges for the Next Generation of Type 2 Translation Research and Systems: The Translation Science to Population Impact (TSci Impact) Framework

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Society for Prevention Research Type 2 Translational Task Force Members and Contributing Authors, Spoth, Richard, Rohrbach, Louise A., Greenberg, Mark, Leaf, Philip, Brown, C. Hendricks, Fagan, Abigail, Catalano, Richard F. +3 more·2013·Prevention Science

Abstract

Evidence-based preventive interventions developed over the past two decades represent great potential for enhancing public health and well-being. Research confirming the limited extent to which these interventions have been broadly and effectively implemented, however, indicates much progress is needed to achieve population-level impact. In part, progress requires Type 2 translation research that investigates the complex processes and systems through which evidence-based interventions are adopted, implemented, and sustained on a large scale, with a strong orientation toward devising empirically-driven strategies for increasing their population impact. In this article, we address two core challenges to the advancement of T2 translation research: (1) building infrastructure and capacity to support systems-oriented scaling up of evidence-based interventions, with well-integrated practice-oriented T2 research, and (2) developing an agenda and improving research methods for advancing T2 translation science. We also summarize a heuristic "Translation Science to Population Impact (TSci Impact) Framework." It articulates key considerations in addressing the core challenges, with three components that represent: (1) four phases of translation functions to be investigated (pre-adoption, adoption, implementation, and sustainability); (2) the multiple contexts in which translation occurs, ranging from community to national levels; and (3) necessary practice and research infrastructure supports. Discussion of the framework addresses the critical roles of practitioner-scientist partnerships and networks, governmental agencies and policies at all levels, plus financing partnerships and structures, all required for both infrastructure development and advances in the science. The article concludes with two sets of recommended action steps that could provide impetus for advancing the next generation of T2 translation science and, in turn, potentially enhance the health and well-being of subsequent generations of youth and families.

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  • Many studies have deplored the tendency for programs to lose funding, focus, or purpose once initial investments are removed.

    “Many studies have deplored the tendency for programs to lose funding, focus, or purpose once the initial investments are removed [71, 72].”

    From Social Network Analysis for Program Implementation (2015) · cites this paper as [72]

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  1. Flay BR Biglan A Boruch RF Castro FG Gottfredson D Kellam S Ji P Standards of evidence: Criteria for efficacy, effectiveness and dissemination Prevention Science 2005 6 151 175 10.1007/s11121-005-5553-y 16365954 · DOI · Paper page
  2. Greenberg MT Domitrovich CE Graczyk PA Zins JE The study of implementation in school-based preventive interventions: Theory, research, and practice (vol. 3) 2005 Rockville Center for Mental Health Services, SAMHSA
  3. World Health Organization The global burden of disease: 2004 update 2008 Geneva WHO Press

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Authors
Society for Prevention Research Type 2 Translational Task Force Members and Contributing Authors, Spoth, R., Rohrbach, L. A., Greenberg, M., Leaf, P., Brown, C. H., Fagan, A., Catalano, R. F., Pentz, M. A., Sloboda, Z., & Hawkins, J. D.
Affiliations
  • Iowa State University (US)
  • University of Southern California (US)
  • Pennsylvania State University (US)
  • Johns Hopkins University (US)
  • University of Miami (US)
  • Florida State University (US)
  • University of Washington (US)
  • JBS International (United States) (US)
Corresponding author
Spoth, Richard
Venue
Prevention Science
Published
2013-02-21
Volume
14
Issue
4
Pages
319-351
ISSN
  • 1389-4986 (ISSN-L)
  • 1573-6695
OpenAlex
W2002173750
Cited by
283
References
218
Citations by year
2026: 8 · 2025: 8 · 2024: 7 · 2023: 13 · 2022: 17 · 2021: 23 · 2020: 32 · 2019: 35 · 2018: 29 · 2017: 26 · 2016: 23 · 2015: 36 · 2014: 19 · 2013: 6 · 2012: 1
FWCI
50.72
Type
journal article
Language
en
Open access
Locations
  • Prevention Science (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • Research Explorer (The University of Manchester) (submittedVersion)
Funders
  • National Institutes of Health (5r13da021047-09)
  • National Institute on Drug Abuse (P30DA027828, 5R13DA021047-08SI, R01DA013709, 5R13DA021047-09, R13 DA021047)
  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (R24HD042828)
Topics
  • Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
  • Health Sciences › Health Professions › General Health Professions › Health Sciences Research and Education
  • Health Sciences › Health Professions › Speech and Hearing › School Health and Nursing Education
Keywords
scaling up interventions, population effects, implementation research, practice-oriented research, research infrastructure, research networks, health policy
MeSH terms
Evidence-Based Practice, Translational Research, Biomedical

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