Challenges and opportunities in global mental health: a research-to-practice perspective
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Purpose of review Globally, the majority of those who need mental health care worldwide lack access to high-quality mental health services. Stigma, human resource shortages, fragmented service delivery models, and lack of research capacity for implementation and policy change contribute to the current mental health treatment gap. In this review, we describe how health systems in low- and middle-income countries (LMICs) are addressing the mental health gap and further identify challenges and priority areas for future research.Recent findings Common mental disorders are responsible for the largest proportion of the global burden of disease; yet, there is sound evidence that these disorders, as well as severe mental disorders, can be successfully treated using evidence-based interventions delivered by trained lay health workers in low-resource community or primary care settings. Stigma is a barrier to service uptake. Prevention, though necessary to address the mental health gap, has not solidified as a research or programmatic focus. Research-to-practice implementation studies are required to inform policies and scale-up services. Four priority areas are identified for focused attention to diminish the mental health treatment gap and to improve access to high-quality mental health services globally: diminishing pervasive stigma, building mental health system treatment and research capacity, implementing prevention programs to decrease the incidence of mental disorders, and establishing sustainable scale up of public health systems to improve access to mental health treatment using evidence-based interventions.
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Stigma is a force that can exert powerful influences on perceptions of mental health issues and treatments across all social actors and processes, including the intervention domain.
“it became apparent in our framework refinement process that, particularly in mental health, stigma (e.g. self-stigma, family/community stigma, provider stigma, organizational or institutional-level stigma) is a force that can exert powerful influences on perceptions of mental health issues and treatments across all social actors and processes—including those in the intervention domain [39–42].”
From Barriers and facilitators to implementation of evidence-based task-sharing mental health interventions in low- and middle-income countries: a systematic review using implementation science frameworks (2022) · cites this paper as [42]
In “Reducing Mental Illness Stigma” (page unavailable), the paper says stigma discourages care-seeking, perpetuates misconceptions about whether mental illness can be cured, and may affect the standing of mental health professions. Its “Stigma” section also links prejudice and discrimination to delayed or prevented treatment. These passages support a powerful influence on perceptions and treatment uptake, but do not establish an influence across all social actors and processes, including every part of the intervention domain. (LLM, conf=0.82)
Experimental — accuracy not yet measuredAccess to mental health care has not expanded to adequately meet the demand.
“existing models of mental health care will not adequately expand to meet the demand”
From The Opportunities and Risks of Large Language Models in Mental Health (2024) · cites this paper as [4]
Evidence-based psychotherapy studies in low- and middle-income countries rarely address sustainability by examining the research-to-practice gap or using human resources that do not depend on research funding.
“Further, these studies seldom address sustainability by evaluating the mental health research-to-practice gap or leveraging human resources not dependent on research funding.4”
From Technology and implementation science to forge the future of evidence-based psychotherapies: The PRIDE scale-up study (2021) · cites this paper as [4]
A widely recognized mental health treatment gap exists whereby more individuals are diagnosed with mental health problems than those who receive treatment.
“This has led to a widely recognized mental health treatment gap, whereby more individuals are diagnosed with mental health problems than those who receive treatment [14, 15].”
From Explaining adults’ mental health help-seeking through the lens of the theory of planned behavior: A scoping review (2022) · cites this paper as [15]
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Lessons learned in developing community mental health care in Latin American and Caribbean countries
Razzouk, D., Gregório, G., ANTUNES, R., & Mari, J. D. J. (2012) · World Psychiatry · doi:10.1002/j.2051-5545.2012.tb00130.x · Cited by 48 · see citing works
Evidence-based mental health care and implementation science in low- and middle-income countries
Thornicroft, G. (2012) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796012000261 · Cited by 43 · see citing works
Caqueo‐Urízar, A., Alfonso Urzúa, M., Jamett, P. R., & Irarrázaval, M. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.01.013 · Cited by 31 · see citing works
Kohrt, B. A., Yang, M.-Y., Rai, S., Bhardwaj, A., Tol, W. A., & Jordans, M. J. D. (2016) · Peace and Conflict Journal of Peace Psychology · doi:10.1037/pac0000170 · Cited by 28 · see citing works
Mental Health Research in the Global Era: Training the Next Generation
Sweetland, A. C., Oquendo, M. A., Carlson, C., Magidson, J. F., & Wainberg, M. L. (2015) · Academic Psychiatry · doi:10.1007/s40596-015-0437-3 · Cited by 25 · see citing works
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Nguyen, T. Q., Bandeen‐Roche, K., German, D., Nguyen, N. T., Bass, J., & Knowlton, A. R. (2016) · LGBT Health · doi:10.1089/lgbt.2015.0017 · Cited by 24 · see citing works
Early intervention for psychosis in low- and middle-income countries needs a public health approach
Farooq, S. (2013) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.112.113761 · Cited by 21 · see citing works
Lessons learned in developing community mental health care in Australasia and the South Pacific
MCGEORGE, P. (2012) · World Psychiatry · doi:10.1016/j.wpsyc.2012.05.010 · Cited by 20 · see citing works
Lesbian, gay, bisexual, and transgender health disparities are a global concern
(2016) · Nursing Outlook · doi:10.1016/j.outlook.2016.02.004 · Cited by 7 · see citing works
Scaling up mental health care in resource‐poor settings
Saxena, S., Saraceno, B., & Granstein, J. (2013) · doi:10.1002/9781118337981.ch2 · Cited by 5 · see citing works
The Editorial Leadership of Academic Psychiatry
Hsin, H. (2016) · Academic Psychiatry · doi:10.1007/s40596-015-0467-x · Cited by 2 · see citing works
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- [47]Sweetland AC Oquendo MA Carlson C Magidson JF Wainberg ML Mental health research in the global era: training the next generation Acad Psychiatry 2016 40 4 715 20 26497971 PMC4842156
- [51]Da Silva TFC Lovisi G Conover S Susser E Critical time intervention–task shifting (CTI-TS): a psychosocial intervention for people with severe mental illness in Latin America Global Advanced Research Journal of Medicine and Medical Sciences 2014 3 5 087 9
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Stigma in health facilities: Why it matters and how we can change it
Nyblade, L., Stockton, M. A., Giger, K., Bond, V., Ekstrand, M. L., Lean, R. M., Mitchell, E. M. H., Nelson, L. R. E., Sapag, J. C., Siraprapasiri, T., et al. (2019) · BMC Medicine · doi:10.1186/s12916-019-1256-2 · Cited by 881 · see citing works
Skin-Interfaced Wearable Sweat Sensors for Precision Medicine
Min, J., Tu, J., Xu, C., Lukas, H., Shin, S., Yang, Y., Solomon, S. A., Mukasa, D., & Gao, W. F. (2023) · Chemical Reviews · doi:10.1021/acs.chemrev.2c00823 · Cited by 728 · see citing works
Mental health and HIV/AIDS: the need for an integrated response
Remien, R. H., Stirratt, M. J., Nguyen, N., Robbins, R. N., Pala, A. N., & Mellins, C. A. (2019) · AIDS · doi:10.1097/qad.0000000000002227 · Cited by 727 · see citing works
The Prevalence of Depression, Anxiety and Stress and Their Associated Factors in College Students.
Ramón-Arbués, E., Gea-Caballero, V., Granada-López, J. M., Juárez-Vela, R., Pellicer-García, B., & Antón-Solanas, I. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17197001 · Cited by 637 · see citing works
“Yet, mental health problems are the first cause of disability and a major public health issue worldwide due to disease progression, difficulties in therapeutic management and increasing prevalence [2,3].”
BackgroundResult(2020) · doi:10.4178/epih.e2020038 · Cited by 741 · see citing works
“Eighth, awareness is one of the key determinants of mental health among individuals and populations [59].”
BackgroundEnhancing mental health with Artificial Intelligence: Current trends and future prospects
Olawade, D. B., Wada, O. Z., Odetayo, A., David-Olawade, A. C., Asaolu, F. T., & Eberhardt, J. (2024) · Journal of Medicine Surgery and Public Health · doi:10.1016/j.glmedi.2024.100099 · Cited by 598 · see citing works
“The conventional approach, which heavily relies on in-person consultations and therapies, falls short of addressing the increasing demand for accessible, affordable, and easily expandable mental health services [4].”
BackgroundHalat, D. H., Soltani, A., Dalli, R., Alsarraj, L., & Malki, A. M. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12134425 · Cited by 378 · see citing works
Le, P. D., Eschliman, E. L., Grivel, M. M., Tang, J., Cho, Y. G., Yang, X., Tay, C., Li, T., Bass, J., & Yang, L. H. (2022) · Implementation Science · doi:10.1186/s13012-021-01179-z · Cited by 233 · see citing works
Raviola, G., Naslund, J. A., Smith, S. L., & Patel, V. (2019) · Current Psychiatry Reports · doi:10.1007/s11920-019-1028-x · Cited by 258 · see citing works
Lazarus, J. V., Ratzan, S., Palayew, A., Billari, F. C., Binagwaho, A., Kimball, S., Larson, H. J., Melegaro, A., Rabin, K., White, T. M., et al. (2020) · PLOS ONE · doi:10.1371/journal.pone.0240011 · Cited by 232 · see citing works
“79), given the increase in anxiety and depression during the pandemic [51], but it also exposes the underlying weaknesses of mental health services in a number of settings, as well the global challenges of fragmented health systems to reach populations that need mental health services [52].”
BackgroundMachine learning model to predict mental health crises from electronic health records
Garriga, R., Mas, J., Abraha, S., Nolan, J., Harrison, O., Tadros, G., & Matic, A. (2022) · Nature Medicine · doi:10.1038/s41591-022-01811-5 · Cited by 229 · see citing works
The Opportunities and Risks of Large Language Models in Mental Health
Lawrence, H. R., Schneider, R. A., Rubin, S. B., Matarić, M. J., McDuff, D. J., & Jones Bell, M. (2024) · JMIR Mental Health · doi:10.2196/59479 · Cited by 235 · see citing works
“Despite greater attention provided in the recent years to mental health, the rate of mental health concerns has increased [2,3], and access to mental health care has not expanded to adequately meet the demand [4].”
BackgroundTo chat or bot to chat: Ethical issues with using chatbots in mental health
Coghlan, S., Leins, K., Sheldrick, S., Cheong, M., Gooding, P., & D’Alfonso, S. (2023) · Digital Health · doi:10.1177/20552076231183542 · Cited by 247 · see citing works
Resilience as a focus of suicide research and prevention
Sher, L. (2019) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13059 · Cited by 199 · see citing works
“Many people around the world who are at a high suicide risk have a limited or no access to mental health care and to information on resilience (116).”
BackgroundAntiporta, D. A., & Bruni, A. (2020) · Revista Panamericana de Salud Pública · doi:10.26633/rpsp.2020.154 · Cited by 186 · see citing works
An AI-based decision support system for predicting mental health disorders
Tutun, S., Johnson, M. E., Ahmed, A., Albizri, A., Irgil, S., Yesilkaya, I., Ucar, E. N., Sengun, T., & Harfouche, A. (2023) · Information Systems Frontiers · doi:10.1007/s10796-022-10282-5 · Cited by 177 · see citing works
“However, a significant proportion of individuals with mental illnesses do not receive treatment or the quality of care they need, often due to resource shortages (Docrat et al., 2019; Petersen et al., 2019; Wainberg et al., 2017; Wang & Cheung, 2011).”
BackgroundKowal, M., Conroy, E., Ramsbottom, N., Smithies, T. D., Toth, A. J., & Campbell, M. J. (2021) · JMIR Serious Games · doi:10.2196/26575 · Cited by 192 · see citing works
“With state-provided health care systems already overwhelmed, the cost barrier of private treatment is felt more acutely and contributes to increasing the socioeconomic divide in terms of access to mental health treatment [17].”
BackgroundSaeidnia, H. R., Fotami, S. G. H., Lund, B. D., & Ghiasi, N. (2024) · Social Sciences · doi:10.3390/socsci13070381 · Cited by 202 · see citing works
“What are the best practices, guidelines, and recommendations for promoting ethical use of AI in mental health interventions?”
Mughal, A. Y., Devadas, J., Ardman, E., Levis, B., Go, V. F.-L., & Gaynes, B. N. (2020) · BMC Psychiatry · doi:10.1186/s12888-020-02753-3 · Cited by 172 · see citing works
Shelton, R. C., Lee, M., Brotzman, L., Wolfenden, L., Nathan, N., & Wainberg, M. L. (2020) · International Journal of Behavioral Medicine · doi:10.1007/s12529-020-09848-x · Cited by 143 · see citing works
“Given a severe lack of capacity for deliveringmental health treatment and very few trainedmental health professionals available, there is the need for taskshifting delivery approaches to address mental health needs [167].”
BackgroundSelf-citationAbd-Alrazaq, A., AlSaad, R., Shuweihdi, F., Ahmed, A., Aziz, S., & Sheikh, J. (2023) · npj Digital Medicine · doi:10.1038/s41746-023-00828-5 · Cited by 138 · see citing works
“Furthermore, shortage of mental health professionals worldwide is one of the largest barriers to detecting depression in its early stages 2,4 .”
Uphoff, E., Robertson, L., Cabieses, B., V, Villalón, F., Purgato, M., Churchill, R. C., & Barbui, C. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd013458.pub2 · Cited by 137 · see citing works
“While most research on involuntary migrants takes place in high-income countries, most live in low- and middle-income countries (Wainberg 2017).”
BackgroundAlhuwaydi, A. M. (2024) · Risk Management and Healthcare Policy · doi:10.2147/rmhp.s461562 · Cited by 152 · see citing works
“12,13 According to the American Psychological Association’s new report, the need for mental healthcare professionals is on the rise, and they are unable to cater the service to new patients.”
BackgroundThird-party evaluators perceive AI as more compassionate than expert humans
Ovsyannikova, D., de Mello, V. O., & Inzlicht, M. (2025) · Communications Psychology · doi:10.1038/s44271-024-00182-6 · Cited by 143 · see citing works
Muhorakeye, O., & Biracyaza, E. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.638377 · Cited by 139 · see citing works
Freţian, A. M., Graf, P., Kirchhoff, S., Glinphratum, G., Bollweg, T. M., Sauzet, O., & Bauer, U. (2021) · International Journal of Public Health · doi:10.3389/ijph.2021.1604072 · Cited by 127 · see citing works
Adams, C., Gringart, E., & Strobel, N. (2022) · Systematic Reviews · doi:10.1186/s13643-022-02034-y · Cited by 115 · see citing works
Global rural health disparities in Alzheimer's disease and related dementias: State of the science
Wiese, L. K., Gibson, A., Guest, M. A., Nelson, A. R., Weaver, R. H., Gupta, A., Carmichael, O. T., Lewis, J., Lindauer, A., Loi, S. M., et al. (2023) · Alzheimer s & Dementia · doi:10.1002/alz.13104 · Cited by 107 · see citing works
Global unmet psychosocial needs in cancer care: health policy
Bergerot, C. D., Jacobsen, P. B., Rosa, W. E., Lam, W., Dunn, J. C., Gonzalez, L. F., Mehnert, A., Veeraiah, S., & Li, M. (2024) · EClinicalMedicine · doi:10.1016/j.eclinm.2024.102942 · Cited by 102 · see citing works
Mohamed, E. S., Naqishbandi, T. A., Bukhari, S. A. C., Rauf, I., Sawrikar, V., & Hussain, A. (2023) · Healthcare Analytics · doi:10.1016/j.health.2023.100185 · Cited by 115 · see citing works
Thiyagarajan, A., James, T. G., & Marzo, R. R. (2022) · Humanities and Social Sciences Communications · doi:10.1057/s41599-022-01229-x · Cited by 99 · see citing works
“In low- and middle-income countries, the lack of sustainable care, stigma, and the low awareness of mental health disorders are major factors contributing to their higher burden (Rathod et al., 2017; Wainberg et al., 2017).”
BackgroundWar Psychiatry: Identifying and Managing the Neuropsychiatric Consequences of Armed Conflicts
Jain, N., Prasad, S., Czárth, Z. C., Chodnekar, S. Y., Mohan, S., Savchenko, E., Panag, D. S., Tanasov, A., Betka, M. M., Płatos, E., et al. (2022) · Journal of Primary Care & Community Health · doi:10.1177/21501319221106625 · Cited by 98 · see citing works
Can AI replace psychotherapists? Exploring the future of mental health care
Zhang, Z., & Wang, J. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1444382 · Cited by 112 · see citing works
Does Psychedelic Therapy Have a Transdiagnostic Action and Prophylactic Potential?
Kočárová, R., Horáček, J., & Carhart-Harris, R. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.661233 · Cited by 96 · see citing works
Purgato, M., Uphoff, E., Singh, R. K., Pachya, A. T., Abdulmalik, J. O., & van Ginneken, N. (2020) · Epidemiology and Psychiatric Sciences · doi:10.1017/s204579602000061x · Cited by 96 · see citing works
Guemghar, I., Padilha, P. P. D. O., Abdel‐Baki, A., Jutras‐Aswad, D., Paquette, J., & Pomey, M. (2022) · JMIR Mental Health · doi:10.2196/36094 · Cited by 90 · see citing works
Depression underdiagnosis: Prevalence and associated factors. A population-based study
Faisal‐Cury, A., Ziebold, C., Rodrigues, D. M. D. O., & Matijasevich, A. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.04.025 · Cited by 86 · see citing works
González-Martín, A., Aibar-Almazán, A., Rivas-Campo, Y., Castellote-Caballero, Y., & Carcelén-Fraile, M. D. C. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1284632 · Cited by 88 · see citing works
“Furthermore, most studies focus on the identification of mental health problems rather than examining in depth effective strategies and approaches to address these issues (14).”
BackgroundSarikhani, Y., Bastani, P., Rafiee, M., Kavosi, Z., & Ravangard, R. (2020) · Community Mental Health Journal · doi:10.1007/s10597-020-00619-2 · Cited by 92 · see citing works
Vaidyam, A. N., Linggonegoro, D. W., & Torous, J. B. (2020) · The Canadian Journal of Psychiatry · doi:10.1177/0706743720966429 · Cited by 83 · see citing works
“The need for digital tools in mental health is clear, with insufficient access to mental health services worldwide and clinical staff increasingly unable to meet rising demand.(1) The World Health Organization (WHO) reports that depression is a leading cause of disability worldwide.”
BackgroundRim, S. J., Hahm, B., Seong, S. J., Park, J. E., Chang, S. M., Kim, B., An, H., Jeon, H. J., Hong, J. P., & Park, S. (2023) · Psychiatry Investigation · doi:10.30773/pi.2022.0307 · Cited by 82 · see citing works
PUBLIC MENTAL HEALTH IN POST-COVID-19 ERA
Ren, F., & Guo, R. (2020) · Psychiatria Danubina · doi:10.24869/psyd.2020.251 · Cited by 104 · see citing works
“More than half of the interviewees have mental health problems in major public health emergencies and have a strong need for psychological assistance (Wainberg et al. 2017).”
BackgroundMental health interventions by lay counsellors: a systematic review and meta-analysis
Connolly, S. M., Vanchu-Orosco, M., Warner, J., Seidi, P. A.-M., Edwards, J., Boath, E., & Irgens, A. C. (2021) · Bulletin of the World Health Organization · doi:10.2471/blt.20.269050 · Cited by 79 · see citing works
“countries actually reflects deeper systemic global problems, such as the unequal distribution of resources and vast disparities in income.(13) The use of lay counsellors could also be problematic.”
BackgroundMandal, P. K., Gaur, S., Roy, R. G., Samkaria, A., Ingole, R., & Goel, A. (2022) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.2c00420 · Cited by 77 · see citing works
Hossain, M. M., Sultana, A., & Purohit, N. (2020) · SSRN Electronic Journal · doi:10.2139/ssrn.3561265 · Cited by 75 · see citing works
LGBTQ youth mental health during COVID-19: unmet needs in public health and policy
Ormiston, C. K., & Williams, F. (2021) · The Lancet · doi:10.1016/s0140-6736(21)02872-5 · Cited by 74 · see citing works
Wagenaar, B. H., Hammett, W. H., Jackson, C., Atkins, D. L., Belus, J. M., & Kemp, C. G. (2020) · Cambridge Prisms Global Mental Health · doi:10.1017/gmh.2020.1 · Cited by 73 · see citing works
A scoping review on monitoring mental health using smart wearable devices
Long, N., Lei, Y., Peng, L., Xu, P., & Mao, P. (2022) · Mathematical Biosciences & Engineering · doi:10.3934/mbe.2022369 · Cited by 72 · see citing works
Kayiteshonga, Y., Sezibera, V., Mugabo, L., & Iyamuremye, J. D. (2022) · BMC Public Health · doi:10.1186/s12889-022-14165-x · Cited by 71 · see citing works
Kearney, C. A., Dupont, R., Fensken, M., & Gonzálvez, C. (2023) · Frontiers in Education · doi:10.3389/feduc.2023.1253595 · Cited by 71 · see citing works
Kargarandehkordi, A., Li, S., Lin, K., Phillips, K. T., Benzo, R. M., & Washington, P. Y. (2025) · Biosensors · doi:10.3390/bios15040202 · Cited by 72 · see citing works
“Mental health disorders have a global prevalence rate exceeding 10%, affecting approximately 450 million individuals [4,5].”
Economic evaluation and costs of telepsychiatry programmes: A systematic review
Naslund, J. A., Mitchell, L. M., Joshi, U., Nagda, D., & Lu, C. (2022) · Journal of Telemedicine and Telecare · doi:10.1177/1357633x20938919 · Cited by 64 · see citing works
Mapping the effectiveness of integrating mental health in HIV programs: a scoping review
Conteh, N. K., Latona, A., & Mahomed, O. H. (2023) · BMC Health Services Research · doi:10.1186/s12913-023-09359-x · Cited by 81 · see citing works
Babatunde, G. B., van Rensburg, A. J., Bhana, A., & Petersen, I. (2019) · Global Social Welfare · doi:10.1007/s40609-019-00158-z · Cited by 70 · see citing works
Nakkeeran, N., & Nakkeeran, B. (2018) · Health Research Policy and Systems · doi:10.1186/s12961-018-0366-1 · Cited by 67 · see citing works
Melo, A. P. S., Dippenaar, I. N., Johnson, S. C., Weaver, N. D., de Assis Acurcio, F., Malta, D. C., Ribeiro, A. L. P., Júnior, A. A. G., Wool, E. E., Naghavi, M., et al. (2022) · The Lancet Psychiatry · doi:10.1016/s2215-0366(22)00237-1 · Cited by 66 · see citing works
Uphoff, E., Newbould, L., Walker, I., Ashraf, N., Chaturvedi, S. K., Kandasamy, A., Mazumdar, P., Meader, N., Naheed, A., Rana, R. Z., et al. (2019) · Journal of Global Health · doi:10.7189/jogh.09.020417 · Cited by 71 · see citing works
Barello, S., Anderson, G., Acampora, M., Bosio, C., Guida, E., Irace, V., Guastoni, C., Bertani, B., & Graffigna, G. (2022) · International Urology and Nephrology · doi:10.1007/s11255-022-03374-3 · Cited by 79 · see citing works
“Psychological interventions are often complex in nature, necessitating time to impact the process of illness elaboration and the actual patient's ability to effectively cope with the disease’s mental health effects [61].”
BackgroundLeonard, E., Kock, I. D., & Bam, W. G. (2020) · Evaluation and Program Planning · doi:10.1016/j.evalprogplan.2020.101832 · Cited by 62 · see citing works
Mans, K., Kettner, H., Erritzøe, D., Haijen, E. C. H. M., Kaelen, M., & Carhart-Harris, R. L. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.647909 · Cited by 60 · see citing works
“The finding that scores on the Staying Well factor were increased at all three follow-up time points, also hints at psychedelics’ prophylactic potential (40), bearing relevance to a current rethinking in mental healthcare toward proactive (preventive), rather than reactive interventions (10, 11).”
BackgroundHuman rights in mental healthcare; A review of current global situation
Mahdanian, A., Laporta, M., Bold, N. D., Funk, M., & Puras, D. (2022) · International Review of Psychiatry · doi:10.1080/09540261.2022.2027348 · Cited by 62 · see citing works
Barriers and facilitators to mental health care: A systematic review in Pakistan
Choudhry, F. R., Khan, N., & Munawar, K. (2021) · International Journal of Mental Health · doi:10.1080/00207411.2021.1941563 · Cited by 63 · see citing works
“Almost 90% of people with mental health problems in Low-middleincome-countries (LMIC) do not receive treatment (Bower & Gilbody, 2005; Patel et al., 2007; 2009; Rathod et al., 2017; Rubenstein et al., 1999; Wainberg et al., 2017; Wang et al., 2007).”
BackgroundCollopy, C. M., Cosh, S., & Tully, P. J. (2021) · BMC Health Services Research · doi:10.1186/s12913-020-06030-7 · Cited by 57 · see citing works
“How to best facilitate buy-in to psychology services and enhance mental health uptake remain ongoing challenges for reducing mental health burden globally (40).”
BackgroundPeña, V. L., Rubí-González, P., & Parada, B. V. (2021) · Revista Panamericana de Salud Pública · doi:10.26633/rpsp.2021.158 · Cited by 55 · see citing works
Luo, Y., Cui, Z., Zou, P., Wang, K., Lin, Z., He, J., & Wang, J. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17165944 · Cited by 54 · see citing works
“One possible reason for this high positive rate might be a low rate of the use of mental health services in China due to pervasive stigma, human resource shortages, and fragmented service delivery models [37,38].”
BackgroundZhang, T., Yin, X., Chen, H., Li, Y., Chen, J., & Yang, X. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.155366 · Cited by 53 · see citing works
Nilsén, P., Svedberg, P., Nygren, J., Frideros, M., Johansson, J., & Schueller, S. M. (2022) · Implementation Research and Practice · doi:10.1177/26334895221112033 · Cited by 56 · see citing works
“Public stigma against mental health disorders and those who receive care is a common concern that also functions as a barrier (Gulliver et al., 2010; Wainberg et al., 2017).”
BackgroundTerrana, A., & Al‐Delaimy, W. K. (2023) · Transcultural Psychiatry · doi:10.1177/13634615231167661 · Cited by 66 · see citing works
Saleem, S. M., Shoib, S., Dazhamyar, A. R., & Chandradasa, M. (2021) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2021.102854 · Cited by 52 · see citing works
Aldridge, L. R., Kemp, C. G., Bass, J., Danforth, K., Kane, J. C., Hamdani, S. U., Marsch, L. A., Uribe-Restrepo, J. M., Nguyen, A. J., Bolton, P. A., et al. (2022) · Implementation Science Communications · doi:10.1186/s43058-022-00301-6 · Cited by 48 · see citing works
“In mental health, as in many areas of health, the gap between evidence and practice is typically greatest in LMIC [6] and implementation science has been recognized as the next step in the evolution of global mental health [7, 8].”
Mental Disorders and Mental Health Promotion in Police Officers
Santre, S. (2024) · Health Psychology Research · doi:10.52965/001c.93904 · Cited by 63 · see citing works
Mutamba, B. B., Kane, J. C., de Jong, J. T. V. M., Okello, J., Musisi, S., & Kohrt, B. A. (2018) · Psychological Medicine · doi:10.1017/s0033291718000193 · Cited by 50 · see citing works
“The implementation of evidence-based interventions for mental, neurological and substance use (MNS) disorders can reduce the substantial treatment gap in low- and middle-income countries (LMICs), where up to 90% of those in need do not have access to mental health services (Whiteford et al. 2013; Wainberg et al. 2017)…”
Propelling the Global Advancement of School Mental Health
Weist, M. D., Hoover, S., Daly, B. P., Short, K. H., & Bruns, E. J. (2023) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-023-00434-7 · Cited by 49 · see citing works
“Factors such as stigma, shortages of qualified mental health professionals, and fragmented service delivery models contribute to the current mental health treatment gap (Wainberg et al., 2017).”
BackgroundZhang, X., Li, Y., Wang, J., Mao, F., Wu, L., Huang, Y., Sun, J., & Cao, F. (2023) · Journal of Medical Internet Research · doi:10.2196/41298 · Cited by 48 · see citing works
“The shortage of mental health services is a major challenge in mental health care in low-and middle-income countries [39].”
Customizing Emotional Support: How Do Individuals Construct and Interact With LLM-Powered Chatbots
Zheng, X., Li, Z., Gui, X., & Luo, Y. (2025) · CHI Conference on Human Factors in Computing Systems · doi:10.1145/3706598.3713453 · Cited by 50 · see citing works
“However, not everyone can access such tailored professional care due to financial, time, and location constraints [12, 67, 93].”
Zhang, Z., Li, N., Chen, R., Lee, T., Gao, Y.-X., Yuan, Z., Nie, Y., & Sun, T. (2021) · Neurobiology of Stress · doi:10.1016/j.ynstr.2021.100333 · Cited by 48 · see citing works
“Then we used the Ribosomal Database Program (RDP) classifier 2.2 for ASV taxonomy classification (Wang et al., 2007).”
InfluentialDing, K., Wang, S., Xu, W., Lin, L., Liao, D., Chen, H., Tan, W., Huang, J., Hou, C., & Jia, F. (2022) · Asia-Pacific Psychiatry · doi:10.1111/appy.12520 · Cited by 47 · see citing works
“Individuals with lower mental health awareness may be more inclined to seek general medical care rather than specialized mental health care (Wainberg et al., 2017).”
BackgroundUsing network analysis to identify central symptoms of college students' mental health
Ma, S., Yang, J., Xu, J., Zhang, N., Kang, L., Wang, P., Wang, W. J., Yang, B. X., Li, R., Xiang, D., et al. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.05.065 · Cited by 47 · see citing works
Supporting youth mental health with arts-based strategies: a global perspective
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“Despite the extent of this crisis, major gaps persist in the resources needed to investigate and address youth mental health, including shortages of mental health professionals [18–20].”
BackgroundHook, K., & Bogdanov, S. (2021) · The Lancet Regional Health - Europe · doi:10.1016/j.lanepe.2021.100182 · Cited by 45 · see citing works
“Second, a main difficulty in mental health research often revolves around financing, particularly achieving and sustaining funding [2].”
BackgroundInfluentialAccess to mental health for Black youths in Alberta
Salami, B. O., Denga, B., Taylor, R. L., Ajayi, N., Jackson, M., Asefaw, M., & Salma, J. (2021) · Health Promotion and Chronic Disease Prevention in Canada · doi:10.24095/hpcdp.41.9.01 · Cited by 44 · see citing works
“36 Our data analysis encompassed several steps: (1) familiarizing ourselves with data through repeated readings of the transcripts; (2) generating initial codes; (3) searching for themes based on identified codes; (4) reviewing, expanding and refin ing identified themes; (5) defining and nam ing the themes; and (6)…”
MethodThe clinical impact of pharmacist services on mental health collaborative teams: A systematic review
Davis, B. R., Qian, J., Ngorsuraches, S., Jeminiwa, R. N., & Garza, K. B. (2020) · Journal of the American Pharmacists Association · doi:10.1016/j.japh.2020.05.006 · Cited by 43 · see citing works
“Inclusion criteria were as follows: (1) pharmacists were included on mental health collaborative team defined as two or more health care providers working together to provide mental health care to patients, (2) mental health clinical outcomes were measured with a validated tool, and (3) the article was written in Engl…”
Malta, M., de Jesus, J. G., LeGrand, S., Seixas, M., Benevides, B., Silva, M. D. D., Lana, J. S., Huynh, H. V., Belden, C. M., & Whetten, K. (2020) · Global Public Health · doi:10.1080/17441692.2020.1767676 · Cited by 46 · see citing works
Greene, M. C., Huang, T. T. ‐., Giusto, A. M., Lovero, K. L., Stockton, M. A., Shelton, R. C., dos Santos, P., Saúte, F., & Wainberg, M. L. (2021) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000306 · Cited by 39 · see citing works
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Nature-based interventions for vulnerable youth: a scoping review
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“…disciplines can increase the potential for collaborative research efforts and help build capacity of residential and community-based programs to implement research studies, disseminate findings, and add to the evidence base (Cunningham et al. 2015; Thompson et al. 2017; Wainberg et al. 2017).”
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“Although there is abundance of empirical evidence supporting the efficacy of therapies, many people, for a variety of reasons (i.e. due to stigma, lack of access), do not pursue them, and for those who do, adherence is often low (Marrero et al., 2020; Wainberg et al., 2017).”
BackgroundThe Economics of Treatment for Depression
Stecher, C. D., Cloonan, S., & Domino, M. E. (2023) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-061022-040533 · Cited by 42 · see citing works
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Self-citationPharmacogenomic Biomarkers and Their Applications in Psychiatry
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“The World Health Organization (WHO) estimates that about 25% of the population around the world will suffer from at least one mental disorder at some time in their lives [1,2].”
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Understanding Mobile Health and Youth Mental Health: Scoping Review
Ding, X., Wuerth, K., Sakakibara, B., Schmidt, J., Parde, N., Holsti, L., & Barbic, S. (2023) · JMIR mHealth and uHealth · doi:10.2196/44951 · Cited by 30 · see citing works
“Mental health disorders are the leading cause of disability worldwide and are considered a global public health challenge [1,2].”
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Source Free Semi-Supervised Transfer Learning for Diagnosis of Mental Disorders on fMRI Scans
Hu, Y. F., Huang, Z.-A., Liu, R., Xue, X., Sun, X., Song, L., & Tan, K. C. (2023) · IEEE Transactions on Pattern Analysis and Machine Intelligence · doi:10.1109/tpami.2023.3298332 · Cited by 34 · see citing works
“M ENTAL health problems, including autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD), etc., have become a global concern and troubled over 17% of the adult population [1].”
BackgroundNeria, Y., Markowitz, J. C., Amsalem, D., Levi‐Belz, Y., Roe, D., Lurie, I., Bitan, D. T., Wainberg, M. L., & Mendlovic, S. (2025) · Israel Journal of Health Policy Research · doi:10.1186/s13584-025-00682-8 · Cited by 34 · see citing works
Self-citation
- Authors
- Wainberg, M. L., Scorza, P., Shultz, J. M., Helpman, L., Mootz, J. J., Johnson, K. A., Neria, Y., Bradford, J.-M. E., Oquendo, M. A., & Arbuckle, M. R.
- Affiliations
- Columbia University Irving Medical Center (US)
- University of Miami (US)
- Corresponding author
- Wainberg, Milton L.
- ORCID
- Venue
- Current Psychiatry Reports
- Published
- 2017-04-19
- Volume
- 19
- Issue
- 5
- Pages
- 28-28
- ISSN
- 1523-3812 (ISSN-L)
- 1535-1645
- PMC
- PMC5553319
- OpenAlex
- W2606586703
- Cited by
- 875
- References
- 105
- Citations by year
- 2026: 117 · 2025: 179 · 2024: 148 · 2023: 138 · 2022: 111 · 2021: 71 · 2020: 73 · 2019: 24 · 2018: 11 · 2017: 1
- FWCI
- 4.69
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Current Psychiatry Reports (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (T32MH096724)
- Topics
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Psychiatric care and mental health services
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Keywords
- global mental health, mental health treatment gap, access to mental health care, mental health stigma, common mental disorders, severe mental illness, lay health workers, community mental health services, primary care, mental health prevention, implementation research, research capacity building, low- and middle-income countries, mental health policy
- MeSH terms
- Mental Disorders, Health Personnel, Humans, Mental Health, Mental Health Services, Public Health, Global Health
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