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Vascularization is the key challenge in tissue engineering

Novosel, Esther C., Kleinhans, Claudia, Kluger, Petra J.·2011·Advanced Drug Delivery Reviews

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Research works printed but not linked: 191

  1. Meyer, 2005, Tissue engineering: a challenge of today's medicine, Head Face Med., 1, 2, 10.1186/1746-160X-1-2 · doi:10.1186/1746-160x-1-2
  2. Stock, 2001, Tissue engineering: current state and prospects, Annu. Rev. Med., 52, 443, 10.1146/annurev.med.52.1.443 · DOI · Paper page
  3. Levenberg, 2004, Advances in tissue engineering, Curr. Top. Dev. Biol., 61, 113, 10.1016/S0070-2153(04)61005-2 · DOI · Paper page
  4. Ikada, 2006, Challenges in tissue engineering, J. R. Soc., 3, 589, 10.1098/rsif.2006.0124 · DOI · Paper page
  5. Griffith, 2002, Tissue engineering — current challenges and expanding opportunities, Science, 295, 1009, 10.1126/science.1069210 · DOI · Paper page
  6. MacNeil, 2007, Progress and opportunities for tissue-engineered skin, Nature, 445, 874, 10.1038/nature05664 · DOI · Paper page
  7. MacNeil, 2008, Biomaterials for tissue engineering of skin, Materials Today, 11, 26, 10.1016/S1369-7021(08)70087-7 · DOI · Paper page
  8. Clar, 2005, Clinical and cost-effectiveness of autologous chondrocyte implantation for cartilage defects in knee joints: systematic review and economic evaluation, Health technology assessment (Winchester, England), 9, 1
  9. Ruano-Ravina, 2006, Autologous chondrocyte implantation: a systematic review, Osteoarthritis Cartilage, 14, 47, 10.1016/j.joca.2005.07.017 · DOI
  10. M.R. Safran, K. Seiber, The evidence for surgical repair of articular cartilage in the knee, J. Am. Acad. Orthop. Surg., 18 259–266. · doi:10.5435/00124635-201005000-00002
  11. Raimondi, 2006, Engineered tissue as a model to study cell and tissue function from a biophysical perspective, Curr. Drug Discov. Technol., 3, 245, 10.2174/157016306780368126 · DOI
  12. Griffith, 2006, Capturing complex 3D tissue physiology in vitro, Nat. Reviews, 7, 211, 10.1038/nrm1858 · DOI · Paper page
  13. Khetani, 2006, Engineering tissues for in vitro applications, Curr. Opin. Biotechnol., 17, 524, 10.1016/j.copbio.2006.08.009 · DOI
  14. Louekari, 2004, Status and prospects of in vitro tests in risk assessment, Altern. Lab. Anim., 32, 431, 10.1177/026119290403200416 · DOI
  15. Lilienblum, 2008, Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH), Arch. Toxicol., 82, 211, 10.1007/s00204-008-0279-9 · DOI · Paper page
  16. Schechtman, 2002, Implementation of the 3Rs (refinement, reduction, and replacement): validation and regulatory acceptance considerations for alternative toxicological test methods, ILAR J., 43, S85, 10.1093/ilar.43.Suppl_1.S85 · DOI
  17. Lovett, 2009, Vascularization strategies for tissue engineering, Tissue Eng., 15, 353, 10.1089/ten.teb.2009.0085 · DOI · Paper page
  18. Rouwkema, 2008, Vascularization in tissue engineering, Trends Biotechnol., 26, 434, 10.1016/j.tibtech.2008.04.009 · DOI · Paper page
  19. Phelps, 2010, Engineering more than a cell: vascularization strategies in tissue engineering, Curr. Opin. Biotechnol., 21, 704, 10.1016/j.copbio.2010.06.005 · DOI · Paper page
  20. Kannan, 2005, The roles of tissue engineering and vascularisation in the development of micro-vascular networks: a review, Biomaterials, 26, 1857, 10.1016/j.biomaterials.2004.07.006 · DOI · Paper page
  21. Jain, 2005, Engineering vascularized tissue, Nat. Biotechnol., 23, 821, 10.1038/nbt0705-821 · DOI · Paper page
  22. Janssen, 2006, A perfusion bioreactor system capable of producing clinically relevant volumes of tissue-engineered bone: in vivo bone formation showing proof of concept, Biomaterials, 27, 315, 10.1016/j.biomaterials.2005.07.044 · DOI · Paper page
  23. Portner, 2005, Bioreactor design for tissue engineering, J. Biosci. Bioeng., 100, 235, 10.1263/jbb.100.235 · DOI · Paper page
  24. Isenberg, 2006, Building structure into engineered tissues, Materials Today, 9, 54, 10.1016/S1369-7021(06)71743-6 · DOI
  25. van Hinsbergh, 2001, The endothelium: vascular control of haemostasis, Eur. J. Obstet. Gynecol. Reprod. Biol., 95, 198, 10.1016/S0301-2115(00)00490-5 · DOI
  26. Tousoulis, 2010, Endothelial dysfunction: potential clinical implications, Minerva Med., 101, 271
  27. Freestone, 2010, Assessment of endothelial dysfunction, Expert Rev. Cardiovasc. Ther., 8, 557, 10.1586/erc.09.184 · DOI
  28. De Angelis, 1996, Endothelial cell biology and culture methods for drug transport studies, Adv. Drug Deliv. Rev., 18, 193, 10.1016/0169-409X(95)00094-N · DOI
  29. Pries, 2006, Normal endothelium, 1, 10.1007/3-540-32967-6_1 · DOI
  30. Ryan, 1989, Endothelial cell receptors, Adv. Drug Deliv. Rev., 4, 65, 10.1016/0169-409X(89)90038-0 · doi:10.1016/0169-409x(89)90038-0
  31. Trachsel, 2006, Antibodies for angiogenesis inhibition, vascular targeting and endothelial cell transcytosis, Adv. Drug Deliv. Rev., 58, 735, 10.1016/j.addr.2005.11.002 · DOI
  32. Okamoto, 1998, Endocytosis and transcytosis, Adv. Drug Deliv. Rev., 29, 215, 10.1016/S0169-409X(97)00080-X · DOI
  33. Ghinea, 1994, How protein hormones reach their target cells. Receptor-mediated transcytosis of hCG through endothelial cells, J. Cell Biol., 125, 87, 10.1083/jcb.125.1.87 · DOI
  34. Aird, 2007, Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms, Circ. Res., 100, 158, 10.1161/01.RES.0000255691.76142.4a · DOI · Paper page
  35. Aird, 2007, Phenotypic heterogeneity of the endothelium: II. Representative vascular beds, Circ. Res., 100, 174, 10.1161/01.RES.0000255690.03436.ae · DOI · Paper page
  36. Risau, 1997, Mechanisms of angiogenesis, Nature, 386, 671, 10.1038/386671a0 · DOI · Paper page
  37. Risau, 1995, Vasculogenesis, Annu. Rev. Cell Dev. Biol., 11, 73, 10.1146/annurev.cb.11.110195.000445 · DOI · Paper page
  38. Ribatti, 2001, Postnatal vasculogenesis, Mech. Dev., 100, 157, 10.1016/S0925-4773(00)00522-0 · DOI
  39. Patan, 2000, Vasculogenesis and angiogenesis as mechanisms of vascular network formation, growth and remodeling, J. Neurooncol., 50, 1, 10.1023/A:1006493130855 · DOI · Paper page
  40. Laschke, 2006, Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes, Tissue Eng., 12, 2093, 10.1089/ten.2006.12.2093 · DOI · Paper page
  41. Kutcher, 2009, The pericyte: cellular regulator of microvascular blood flow, Microvasc. Res., 77, 235, 10.1016/j.mvr.2009.01.007 · DOI · Paper page
  42. Karamysheva, 2008, Mechanisms of angiogenesis, Biochemistry (Mosc), 73, 751, 10.1134/S0006297908070031 · DOI · Paper page
  43. Holderfield, 2008, Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-beta in vascular morphogenesis, Circ. Res., 102, 637, 10.1161/CIRCRESAHA.107.167171 · DOI · Paper page
  44. Rivron, 2008, Engineering vascularised tissues in vitro, Eur. Cells Mater., 15, 27, 10.22203/eCM.v015a03 · DOI · Paper page
  45. Tremblay, 2005, Inosculation of tissue-engineered capillaries with the host's vasculature in a reconstructed skin transplanted on mice, Am. J. Transplant., 5, 1002, 10.1111/j.1600-6143.2005.00790.x · DOI · Paper page
  46. Fontaine, 1972, Revascularization of the aortio-ilio-femoral trunk, J. Cardiovasc. Surg., 13, 30
  47. Chen, 2009, Prevascularization of a fibrin-based tissue construct accelerates the formation of functional anastomosis with host vasculature, Tissue Eng. A, 15, 1363, 10.1089/ten.tea.2008.0314 · DOI · Paper page
  48. Laschke, 2008, Improvement of vascularization of PLGA scaffolds by inosculation of in situ-preformed functional blood vessels with the host microvasculature, Ann. Surg., 248, 939, 10.1097/SLA.0b013e31818fa52f · DOI
  49. Sekine, 2008, Endothelial cell coculture within tissue-engineered cardiomyocyte sheets enhances neovascularization and improves cardiac function of ischemic hearts, Circulation, 118, S145, 10.1161/CIRCULATIONAHA.107.757286 · DOI · Paper page
  50. Hobo, 2008, Therapeutic angiogenesis using tissue engineered human smooth muscle cell sheets, Arterioscler Throm Vasc Biol., 28, 637, 10.1161/ATVBAHA.107.151829 · DOI
  51. Yang, 2007, Reconstruction of functional tissues with cell sheet engineering, Biomaterials, 28, 5033, 10.1016/j.biomaterials.2007.07.052 · DOI · Paper page
  52. Khouri, 1991, Prefabrication of composite free flaps through staged microvascular transfer: an experimental and clinical study, Plast. Reconstr. Surg., 87, 108, 10.1097/00006534-199101000-00017 · doi:10.1097/00006534-199101000-00017
  53. Morrison, 1990, Prefabrication of thin transferable axial-pattern skin flaps: an experimental study in rabbits, Br. J. Plast. Surg., 43, 645, 10.1016/0007-1226(90)90184-2 · doi:10.1016/0007-1226(90)90184-2
  54. Le Danvic, 1988, Experimental study of the neovascularization of a flap created from a vascular axial loop, Ann. Chir. Plast. Esthét., 33, 377
  55. Lokmic, 2007, An arteriovenous loop in a protected space generates a permanent, highly vascular, tissue-engineered construct, FASEB J., 21, 511, 10.1096/fj.06-6614com · DOI · Paper page
  56. Mian, 2000, Formation of new tissue from an arteriovenous loop in the absence of added extracellular matrix, Tissue Eng., 6, 595, 10.1089/10763270050199541 · doi:10.1089/10763270050199541
  57. Cassell, 2001, The influence of extracellular matrix on the generation of vascularized, engineered, transplantable tissue, Ann. NY Acad. Sci., 944, 429, 10.1111/j.1749-6632.2001.tb03853.x · DOI
  58. Polykandriotis, 2007, Intrinsic axial vascularization of an osteoconductive bone matrix by means of an arteriovenous vascular bundle, Plast. Reconstr. Surg., 120, 855, 10.1097/01.prs.0000277664.89467.14 · DOI
  59. Tanaka, 2000, Generation of an autologous tissue (matrix) flap by combining an arteriovenous shunt loop with artificial skin in rats: preliminary report, Br. J. Plast. Surg., 53, 51, 10.1054/bjps.1999.3186 · doi:10.1054/bjps.1999.3186
  60. Tanaka, 2003, Tissue engineering skin flaps: which vascular carrier, arteriovenous shunt loop or arteriovenous bundle, has more potential for angiogenesis and tissue generation?, Plast. Reconstr. Surg., 112, 1636, 10.1097/01.PRS.0000086140.49022.AB · doi:10.1097/01.prs.0000086140.49022.ab
  61. Nicosia, 1990, Modulation of microvascular growth and morphogenesis by reconstituted basement membrane gel in three-dimensional cultures of rat aorta: a comparative study of angiogenesis in matrigel, collagen, fibrin, and plasma clot, In Vitro Cell. Dev. Biol., 26, 119, 10.1007/BF02624102 · DOI · Paper page
  62. Dvorak, 1987, Fibrin containing gels induce angiogenesis. Implications for tumor stroma generation and wound healing, Lab Invest, 57, 673
  63. Kneser, 2006, Engineering of vascularized transplantable bone tissues: induction of axial vascularization in an osteoconductive matrix using an arteriovenous loop, Tissue Eng., 12, 1721, 10.1089/ten.2006.12.1721 · DOI · Paper page
  64. Ogawa, 2007, Vascular tissue engineering and vascularized 3D tissue regeneration, Regen. Med., 2, 831, 10.2217/17460751.2.5.831 · DOI
  65. Hyakusoku, 1993, Secondary vascularised hair-bearing island flaps for eyebrow reconstruction, Br. J. Plast. Surg., 46, 45, 10.1016/0007-1226(93)90064-I · doi:10.1016/0007-1226(93)90064-i
  66. Nomi, 2006, Role of growth factors and endothelial cells in therapeutic angiogenesis and tissue engineering, Curr. Stem Cell Res. Ther., 1, 333, 10.2174/157488806778226777 · DOI
  67. Santos, 2010, Vascularization in bone tissue engineering: physiology, current strategies, major hurdles and future challenges, Macromol. Biosci., 10, 12, 10.1002/mabi.200900107 · DOI · Paper page
  68. Demirdogen, 2010, Neovascularization by bFGF releasing hyaluronic acid-gelatin microspheres: in vitro and in vivo studies, Growth Factors, 28, 426, 10.3109/08977194.2010.508456 · DOI
  69. Borselli, 2010, Bioactivation of collagen matrices through sustained VEGF release from PLGA microspheres, J Biomed Mater Res A., 92, 94, 10.1002/jbm.a.32332 · DOI
  70. Prokop, 2001, Towards retrievable vascularized bioartificial pancreas: induction and long-lasting stability of polymeric mesh implant vascularized with the help of acidic and basic fibroblast growth factors and hydrogel coating, Diabetes Technol Ther., 3, 245, 10.1089/152091501300209624 · DOI
  71. Ko, 1995, In vitro slow release profile of endothelial cell growth factor immobilized within calcium alginate microbeads, Artif Cells Blood Substit Immobil Biotechnol., 23, 143, 10.3109/10731199509117934 · doi:10.3109/10731199509117934
  72. Edelman, 1991, Controlled and modulated release of basic fibroblast growth factor, Biomaterials., 12, 619, 10.1016/0142-9612(91)90107-L · DOI · Paper page
  73. Karal-Yilmaz, 2011, Preparation and in vitro characterization of vascular endothelial growth factor (VEGF)-loaded poly(d, l-lactic-co-glycolic acid) microspheres using a double emulsion/solvent evaporation technique, J Microencapsul., 28, 46, 10.3109/02652048.2010.523795 · DOI
  74. de Boer, 2010, In vitro and in vivo release of nerve growth factor from biodegradable poly-lactic-co-glycolic-acid microspheres, J Biomed Mater Res A., 95, 1067, 10.1002/jbm.a.32900 · DOI
  75. d'Angelo, 2010, Nanoparticles based on PLGA:poloxamer blends for the delivery of proangiogenic growth factors, Mol Pharm., 10.1021/mp1001262 · DOI
  76. Layman, 2010, Enhanced angiogenic efficacy through controlled and sustained delivery of FGF-2 and G-CSF from fibrin hydrogels containing ionic-albumin microspheres, J Biomater Sci Polym Ed.
  77. Yang, 2007, Effects of myocardial transplantation of marrow mesenchymal stem cells transfected with vascular endothelial growth factor for the improvement of heart function and angiogenesis after myocardial infarction, Cardiology., 107, 17, 10.1159/000093609 · DOI
  78. Zisch, 2003, Biopolymeric delivery matrices for angiogenic growth factors, Cardiovasc Pathol., 12, 295, 10.1016/S1054-8807(03)00089-9 · DOI · Paper page
  79. Andrae, 2008, Role of platelet-derived growth factors in physiology and medicine, Genes Dev., 22, 1276, 10.1101/gad.1653708 · DOI · Paper page
  80. Perets, 2003, Enhancing the vascularization of three-dimensional porous alginate scaffolds by incorporating controlled release basic fibroblast growth factor microspheres, J Biomed Mater Res A., 65, 489, 10.1002/jbm.a.10542 · DOI · Paper page
  81. Thurston, 2002, Complementary actions of VEGF and angiopoietins on blood vessel permeability and growth in mice, J Anat., 200, 529, 10.1046/j.1469-7580.2002.00061.x · DOI
  82. Sun, 2011, Functional neovascularization of biodegradable dextran hydrogels with multiple angio-genic growth factors, Biomaterials., 1, 133
  83. Yao, 2008, The effect of cross-linking of collagen matrices on their angiogenic capability, Biomaterials., 29, 66, 10.1016/j.biomaterials.2007.08.049 · DOI
  84. Saik, 2011, Covalently immobilized platelet-derived growth factor-BB promotes angiogenesis in biomimetic poly(ethylene glycol) hydrogels, Acta biomaterialia., 10.1016/j.actbio.2010.08.018 · DOI · Paper page
  85. Li, 2010, Synergistic effects of FGF-2 and PDGF-BB on angiogenesis and muscle regeneration in rabbit hindlimb ischemia model, Microvasc Res., 80, 10, 10.1016/j.mvr.2009.12.002 · DOI
  86. Hubbell, 1991, Endothelial cell-selective materials for tissue engineering in the vascular graft via a new receptor, Biotechnology (N Y)., 9, 568, 10.1038/nbt0691-568 · DOI · Paper page
  87. Conconi, 2010, Effects on in vitro and in vivo angiogenesis induced by small peptides carrying adhesion sequences, J Pept Sci, 16, 349, 10.1002/psc.1251 · DOI
  88. von der Mark, 2010, Nanoscale engineering of biomimetic surfaces: cues from the extracellular matrix, Cell Tissue Res., 339, 131, 10.1007/s00441-009-0896-5 · DOI · Paper page
  89. Hersel, 2003, RGD modified polymers: biomaterials for stimulated cell adhesion and beyond, Biomaterials, 24, 4385, 10.1016/S0142-9612(03)00343-0 · DOI · Paper page
  90. Shin, 2003, Biomimetic materials for tissue engineering, Biomaterials., 24, 4353, 10.1016/S0142-9612(03)00339-9 · DOI · Paper page
  91. Rosso, 2005, Smart materials as scaffolds for tissue engineering, J Cell Physiol., 203, 465, 10.1002/jcp.20270 · DOI · Paper page
  92. Singh, 2008, Strategies and applications for incorporating physical and chemical signal gradients in tissue engineering, Tissue Eng Part B Rev., 14, 341, 10.1089/ten.teb.2008.0304 · DOI · Paper page
  93. Rao, 2009, Adhesion molecule-modified biomaterials for neural tissue engineering, Front Neuroengineering, 2, 6, 10.3389/neuro.16.006.2009 · DOI
  94. Hamada, 2003, Angiogenic activity of osteopontin-derived peptide SVVYGLR, Biochem Biophys Res Commun., 310, 153, 10.1016/j.bbrc.2003.09.001 · DOI
  95. Miller, 2010, Bioactive hydrogels made from step-growth derived PEG-peptide macromers, Biomaterials, 31, 3736, 10.1016/j.biomaterials.2010.01.058 · DOI · Paper page
  96. Hall, 2004, Heterophilic interactions between cell adhesion molecule L1 and alphavbeta3-integrin induce HUVEC process extension in vitro and angiogenesis in vivo, Angiogenesis., 7, 213, 10.1007/s10456-004-1328-5 · DOI
  97. Chung, 2006, Heparin immobilized porous PLGA microspheres for angiogenic growth factor delivery, Pharm Res., 23, 1835, 10.1007/s11095-006-9039-9 · DOI
  98. Yoon, 2006, Heparin-immobilized biodegradable scaffolds for local and sustained release of angiogenic growth factor, J Biomed Mater Res A., 79, 934, 10.1002/jbm.a.30843 · DOI
  99. Yoon, 2007, Photo-crosslinkable and biodegradable Pluronic/heparin hydrogels for local and sustained delivery of angiogenic growth factor, J Biomed Mater Res A., 83, 597, 10.1002/jbm.a.31271 · DOI
  100. Harvey, 2002, Comparative analysis of in vitro angiogenic activities of endothelial cells of heterogeneous origin, Microvasc. Res., 63, 316, 10.1006/mvre.2002.2406 · doi:10.1006/mvre.2002.2406
  101. Vailhe, 2001, In vitro models of vasculogenesis and angiogenesis, Lab Invest., 81, 439, 10.1038/labinvest.3780252 · DOI · Paper page
  102. Miller-Kasprzak, 2007, Endothelial progenitor cells as a new agent contributing to vascular repair, Arch Immunol Ther Exp (Warsz)., 55, 247, 10.1007/s00005-007-0027-5 · DOI
  103. Chen, 2010, Rapid anastomosis of endothelial progenitor cell-derived vessels with host vasculature is promoted by a high density of cotransplanted fibroblasts, Tissue Eng Part A., 16, 585, 10.1089/ten.tea.2009.0491 · DOI · Paper page
  104. Kim, 2008, Endothelial stem cells and precursors for tissue engineering: cell source, differentiation, selection, and application, Tissue Eng Part B Rev., 14, 133, 10.1089/teb.2007.0304 · DOI
  105. Riha, 2005, Review: application of stem cells for vascular tissue engineering, Tissue Eng., 11, 1535, 10.1089/ten.2005.11.1535 · DOI
  106. Yamahara, 2009, Potential use of endothelial progenitor cells for regeneration of the vasculature, Ther Adv Cardiovasc Dis., 3, 17, 10.1177/1753944708097728 · DOI
  107. Ratliff, 2010, Endothelial progenitors encapsulated in bioartificial niches are insulated from systemic cytotoxicity and are angiogenesis competent, Am J Physiol Renal Physiol., 299, F178, 10.1152/ajprenal.00102.2010 · DOI
  108. Kawamoto, 2002, Transplantation of endothelial progenitor cells for therapeutic neovascularization, Cardiovasc Radiat Med., 3, 221, 10.1016/S1522-1865(03)00082-9 · DOI
  109. Matsumoto, 2008, Fracture induced mobilization and incorporation of bone marrow-derived endothelial progenitor cells for bone healing, J Cell Physiol., 215, 234, 10.1002/jcp.21309 · DOI
  110. Seebach, 2010, Endothelial progenitor cells and mesenchymal stem cells seeded onto beta-TCP granules enhance early vascularization and bone healing in a critical-sized bone defect in rats, Tissue Eng Part A., 16, 1961, 10.1089/ten.tea.2009.0715 · DOI · Paper page
  111. Lee, 2008, Mobilization of endothelial progenitor cells in fracture healing and distraction osteogenesis, Bone., 42, 932, 10.1016/j.bone.2008.01.007 · DOI
  112. Hurley, 2010, Complex temporal regulation of capillary morphogenesis by fibroblasts, Am J Physiol Cell Physiol., 299, C444, 10.1152/ajpcell.00572.2009 · DOI
  113. Unger, 2010, The rapid anastomosis between prevascularized networks on silk fibroin scaffolds generated in vitro with cocultures of human microvascular endothelial and osteoblast cells and the host vasculature, Biomaterials., 31, 6959, 10.1016/j.biomaterials.2010.05.057 · DOI · Paper page
  114. Borges, 2007, In vitro analysis of the interactions between preadipocytes and endothelial cells in a 3D fibrin matrix, Minim Invasive Ther Allied Technol., 16, 141, 10.1080/13645700600935398 · DOI
  115. Chung, 2009, Cell migration into scaffolds under co-culture conditions in a microfluidic platform, Lab Chip., 9, 269, 10.1039/B807585A · DOI · Paper page
  116. Frederick, 2010, Stromal cell-derived factor-1alpha activation of tissue-engineered endothelial progenitor cell matrix enhances ventricular function after myocardial infarction by inducing neovasculogenesis, Circulation., 122, S107, 10.1161/CIRCULATIONAHA.109.930404 · DOI
  117. Aguirre, 2010, Dynamics of bone marrow-derived endothelial progenitor cell/mesenchymal stem cell interaction in co-culture and its implications in angiogenesis, Biochem Biophys Res Commun., 400, 284, 10.1016/j.bbrc.2010.08.073 · DOI · Paper page
  118. McGuigan, 2006, Vascularized organoid engineered by modular assembly enables blood perfusion, Proc Natl Acad Sci U S A., 103, 11461, 10.1073/pnas.0602740103 · DOI · Paper page
  119. Leung, 2010, A modular approach to cardiac tissue engineering, Tissue Eng Part A., 16, 3207, 10.1089/ten.tea.2009.0746 · doi:10.1089/ten.tea.2009.0746
  120. Kelm, 2010, A novel concept for scaffold-free vessel tissue engineering: self-assembly of microtissue building blocks, J Biotechnol., 148, 46, 10.1016/j.jbiotec.2010.03.002 · DOI · Paper page
  121. Linke, 2007, Engineered liver-like tissue on a capillarized matrix for applied research, Tissue Eng., 13, 2699, 10.1089/ten.2006.0388 · DOI
  122. Brown, 2006, Survival and function of transplanted islet cells on an in vivo, vascularized tissue engineering platform in the rat: a pilot study, Cell Transplant., 15, 319, 10.3727/000000006783981909 · doi:10.3727/000000006783981909
  123. Polykandriotis, 2006, [Prevascularisation strategies in tissue engineering], Handchir. Mikrochir Plast Chir., 38, 217, 10.1055/s-2006-924419 · doi:10.1055/s-2006-924419
  124. Badylak, 1989, Small intestinal submucosa as a large diameter vascular graft in the dog, J Surg Res., 47, 74, 10.1016/0022-4804(89)90050-4 · DOI · Paper page
  125. Matsumoto, 1966, A study of inverted intestinal graft in the major veins, Angiology., 17, 842, 10.1177/000331976601701106 · doi:10.1177/000331976601701106
  126. Lantz, 1990, Small intestinal submucosa as a small-diameter arterial graft in the dog, J Invest Surg., 3, 217, 10.3109/08941939009140351 · DOI · Paper page
  127. Lantz, 1992, Small intestinal submucosa as a superior vena cava graft in the dog, J Surg Res., 53, 175, 10.1016/0022-4804(92)90031-T · DOI
  128. Lawler, 1971, Evaluation of canine intestinal submucosa as a vascular substitute, Am J Surg., 122, 517, 10.1016/0002-9610(71)90478-8 · doi:10.1016/0002-9610(71)90478-8
  129. Cebotari, 2002, Construction of autologous human heart valves based on an acellular allograft matrix, Circulation., 106, I63, 10.1161/01.cir.0000032900.55215.85 · DOI
  130. Leyh, 2003, Acellularized porcine heart valve scaffolds for heart valve tissue engineering and the risk of cross-species transmission of porcine endogenous retrovirus, J Thorac Cardiovasc Surg., 126, 1000, 10.1016/S0022-5223(03)00353-2 · DOI
  131. Yu, 2008, Preparation and endothelialization of decellularised vascular scaffold for tissue-engineered blood vessel, J. Mater. Sci., 19, 319, 10.1016/j.msea.2007.05.080 · doi:10.1016/j.msea.2007.05.080
  132. Schultheiss, 2005, Biological vascularized matrix for bladder tissue engineering: matrix preparation, reseeding technique and short-term implantation in a porcine model, J Urol., 173, 276, 10.1097/01.ju.0000145882.80339.18 · DOI
  133. Bader, 1998, Tissue engineering of heart valves — human endothelial cell seeding of detergent acellularized porcine valves, Eur. J. Cardiothorac. Surg., 14, 279, 10.1016/S1010-7940(98)00171-7 · DOI · Paper page
  134. Mertsching, 2005, Engineering of a vascularized scaffold for artificial tissue and organ generation, Biomaterials., 26, 6610, 10.1016/j.biomaterials.2005.04.048 · DOI
  135. Meezan, 1975, A simple, versatile, nondisruptive method for the isolation of morphologically and chemically pure basement membranes from several tissues, Life Sci., 17, 1721, 10.1016/0024-3205(75)90119-8 · DOI · Paper page
  136. Macchiarini, 2004, First human transplantation of a bioengineered airway tissue, J Thorac Cardiovasc Surg., 128, 638, 10.1016/j.jtcvs.2004.02.042 · DOI · Paper page
  137. Walles, 2005, Tissue remodeling in a bioartificial fibromuscular patch following transplantation in a human, Transplantation., 80, 284, 10.1097/01.TP.0000164144.25619.01 · DOI
  138. Biancosino, 2006, Generation of a bioartificial fibromuscular tissue with autoregenerative capacities for surgical reconstruction, Cytotherapy., 8, 178, 10.1080/14653240600621166 · DOI
  139. Ribatti, 2002, Endothelial cell heterogeneity and organ specificity, J Hematother. Stem Cell Res., 11, 81, 10.1089/152581602753448559 · DOI · Paper page
  140. Bär, 2010, The pro-angiogenic factor CCN1 enhances the re-endothelialization of biological vascularized matrices in vitro, Cardiovasc Res., 85, 806, 10.1093/cvr/cvp370 · DOI
  141. Brigstock, 2003, The CCN family: a new stimulus package, J. Endocrinol., 178, 169, 10.1677/joe.0.1780169 · DOI · Paper page
  142. Chen, 2007, Functional properties and intracellular signaling of CCN1/Cyr61, J Cell Biochem., 100, 1337, 10.1002/jcb.21194 · DOI · Paper page
  143. Mertsching, 2009, Generation and transplantation of an autologous vascularized bioartificial human tissue, Transplantation., 88, 203, 10.1097/TP.0b013e3181ac15e1 · DOI
  144. Demarteau, 2003, Dynamic compression of cartilage constructs engineered from expanded human articular chondrocytes, Biochem Biophys Res Commun., 310, 580, 10.1016/j.bbrc.2003.09.099 · doi:10.1016/j.bbrc.2003.09.099
  145. Martin, 2004, The role of bioreactors in tissue engineering, Trends Biotechnol., 22, 80, 10.1016/j.tibtech.2003.12.001 · DOI · Paper page
  146. Chen, 2006, Bioreactors for tissue engineering, Biotechnol Lett., 28, 1415, 10.1007/s10529-006-9111-x · DOI · Paper page
  147. Barron, 2003, Bioreactors for cardiovascular cell and tissue growth: a review, Ann Biomed Eng., 31, 1017, 10.1114/1.1603260 · DOI · Paper page
  148. Ott, 2008, Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart, Nat Med., 14, 213, 10.1038/nm1684 · DOI · Paper page
  149. Perez-Castillejos, 2010, Replication of the 3D architecture of tissues, Materials Today, 13, 10.1016/S1369-7021(10)70015-8 · DOI
  150. Liu, 2005, Engineering biomaterials to control cell function, Materials Today, 8, 28, 10.1016/S1369-7021(05)71222-0 · DOI
  151. Zhang, 2007, Matrices and scaffolds for drug delivery in vascular tissue engineering, Adv Drug Deliv Rev., 59, 360, 10.1016/j.addr.2007.03.018 · DOI
  152. Hollister, 2005, Porous scaffold design for tissue engineering, Nat Mater., 4, 518, 10.1038/nmat1421 · DOI · Paper page
  153. Ma, 2004, Scaffolds for tissue fabrication, Materials Today, 7, 30, 10.1016/S1369-7021(04)00233-0 · DOI · Paper page
  154. Patterson, 2010, Biomimetic materials in tissue engineering, Materials Today, 13, 14, 10.1016/S1369-7021(10)70013-4 · DOI · Paper page
  155. Segura, 2005, DNA delivery from hyaluronic acid-collagen hydrogels via a substrate-mediated approach, Biomaterials., 26, 1575, 10.1016/j.biomaterials.2004.05.007 · DOI · Paper page
  156. Lutolf, 2003, Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics, Proc Natl Acad Sci U S A., 100, 5413, 10.1073/pnas.0737381100 · DOI · Paper page
  157. Ulijn, 2007, Bioresponsive hydrogels, Materials Today, 10, 40, 10.1016/S1369-7021(07)70049-4 · DOI · Paper page
  158. Kikuchi, 1998, Two-dimensional manipulation of confluently cultured vascular endothelial cells using temperature-responsive poly(N-isopropylacrylamide)-grafted surfaces, J Biomater Sci Polym Ed., 9, 1331, 10.1163/156856298X00424 · doi:10.1163/156856298x00424
  159. Krsko, 2005, Biointeractive hydrogels, Materials Today, 8, 36, 10.1016/S1369-7021(05)71223-2 · DOI
  160. Hutmacher, 1996, A review of material properties of biodegradable and bioresorbable polymers and devices for GTR and GBR applications, Int J Oral Maxillofac Implants, 11, 667
  161. Raeber, 2005, Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration, Biophys J., 89, 1374, 10.1529/biophysj.104.050682 · DOI · Paper page
  162. Lee, 2005, Proteolytically degradable hydrogels with a fluorogenic substrate for studies of cellular proteolytic activity and migration, Biotechnol Prog., 21, 1736, 10.1021/bp0502429 · DOI
  163. Miller, 2010, Bioactive hydrogels made from step-growth derived PEG-peptide macromers, Biomaterials., 31, 3736, 10.1016/j.biomaterials.2010.01.058 · DOI · Paper page
  164. Keskar, 2009, Initial evaluation of vascular ingrowth into superporous hydrogels, J Tissue Eng Regen Med., 3, 486, 10.1002/term.183 · DOI
  165. Kasoju, 2009, Preparation and characterization of Antheraea assama silk fibroin based novel non-woven scaffold for tissue engineering applications, J Tissue Eng Regen Med., 3, 539, 10.1002/term.196 · DOI
  166. Cao, 2006, The influence of architecture on degradation and tissue ingrowth into three-dimensional poly(lactic-co-glycolic acid) scaffolds in vitro and in vivo, Biomaterials., 27, 2854, 10.1016/j.biomaterials.2005.12.015 · DOI
  167. Weigel, 2006, Design and preparation of polymeric scaffolds for tissue engineering, Expert Rev Med Devices, 3, 835, 10.1586/17434440.3.6.835 · DOI · Paper page
  168. Hutmacher, 2007, State of the art and future directions of scaffold-based bone engineering from a biomaterials perspective, J Tissue Eng Regen Med., 1, 245, 10.1002/term.24 · DOI · Paper page
  169. P.J. Kluger, R. Wyrwa, J. Weisser, J. Maierle, M. Votteler, C. Rode, M. Schnabelrauch, H. Walles, K. Schenke-Layland, Electrospun poly(d/l-lactide-co-L-lactide) hybrid matrix: a novel scaffold material for soft tissue engineering, J Mater Sci Mater Med. 21 (2010) 2665–2671. · DOI
  170. Votteler, 2010, Stem cell microenvironments — unveiling the secret of how stem cell fate is defined, Macromol Biosci., 10, 1302, 10.1002/mabi.201000102 · DOI
  171. Leong, 2009, In vitro cell infiltration and in vivo cell infiltration and vascularization in a fibrous, highly porous poly(d, l-lactide) scaffold fabricated by cryogenic electrospinning technique, J Biomed Mater Res A., 91, 231, 10.1002/jbm.a.32208 · DOI · Paper page
  172. Fuchs, 2009, Contribution of outgrowth endothelial cells from human peripheral blood on in vivo vascularization of bone tissue engineered constructs based on starch polycaprolactone scaffolds, Biomaterials., 30, 526, 10.1016/j.biomaterials.2008.09.058 · DOI · Paper page
  173. Santos, 2008, Endothelial cell colonization and angiogenic potential of combined nano- and micro-fibrous scaffolds for bone tissue engineering, Biomaterials., 29, 4306, 10.1016/j.biomaterials.2008.07.033 · DOI · Paper page
  174. Bianco, 2010, Microstructure and cytocompatibility of electrospun nanocomposites based on poly(epsilon-caprolactone) and carbon nanostructures, Int J Artif Organs, 33, 271, 10.1177/039139881003300502 · DOI
  175. Fidkowski, 2005, Endothelialized microvasculature based on a biodegradable elastomer, Tissue Eng., 11, 302, 10.1089/ten.2005.11.302 · DOI · Paper page
  176. Bettinger, 2006, Three-dimensional microfluidic tissue-engineering scaffolds using a flexible biodegradable polymer, Adv Mater., 18, 10.1002/adma.200500438 · DOI · Paper page
  177. Bettinger, 2007, Silk fibroin microfluidic devices, Adv Mater., 19, 10.1002/adma.200602487 · DOI · Paper page
  178. Borenstein, 2010, Functional endothelialized microvascular networks with circular cross-sections in a tissue culture substrate, Biomed Microdevices, 12, 71, 10.1007/s10544-009-9361-1 · DOI
  179. Hutmacher, 2007, Concepts of scaffold-based tissue engineering — the rationale to use solid free-form fabrication techniques, J Cell Mol Med, 11, 654, 10.1111/j.1582-4934.2007.00078.x · DOI · Paper page
  180. Xu, 2009, Fabrication and characterization of bio-engineered cardiac pseudo tissues, Biofabrication., 1, 035001, 10.1088/1758-5082/1/3/035001 · DOI · Paper page
  181. Li, 2007, Multiphoton polymerization, Materials Today, 10, 30, 10.1016/S1369-7021(07)70130-X · DOI · Paper page
  182. Saulius Juodkazis, 2005, Kock Khuen Seet, Masafumi Miwa and Hiroaki Misawa, Two-photon lithography of nanorods in SU-8 photoresist, Nanotechnology., 16, 846, 10.1088/0957-4484/16/6/039 · DOI · Paper page
  183. Moon, 2009, Micropatterning of poly(ethylene glycol) diacrylate hydrogels with biomolecules to regulate and guide endothelial morphogenesis, Tissue Eng. A, 15, 579, 10.1089/ten.tea.2008.0196 · DOI · Paper page
  184. Ovsianikov, 2007, Two-photon polymerization technique for microfabrication of CAD-designed 3D scaffolds from commercially available photosensitive materials, J Tissue Eng Regen Med., 1, 443, 10.1002/term.57 · DOI · Paper page
  185. Mironov, 2008, Organ printing: promises and challenges, Regen Med., 3, 93, 10.2217/17460751.3.1.93 · DOI · Paper page
  186. Wang, 2009, A novel copolymer poly(lactide-co-beta-malic acid) with extended carboxyl arms offering better cell affinity and hemacompatibility for blood vessel engineering, Tissue Eng. A, 15, 65, 10.1089/ten.tea.2007.0394 · doi:10.1089/ten.tea.2007.0394
  187. Chung, 2007, Surface engineered and drug releasing pre-fabricated scaffolds for tissue engineering, Adv Drug Deliv Rev., 59, 249, 10.1016/j.addr.2007.03.015 · DOI · Paper page
  188. Laura, 1999, Geometric control of switching between growth, apoptosis, and differentiation during angiogenesis using micropatterned substrates, In Vitro Cell Dev Biol Anim., 35, 441, 10.1007/s11626-999-0050-4 · DOI · Paper page
  189. Gauvreau, 2005, Micropattern printing of adhesion, spreading, and migration peptides on poly(tetrafluoroethylene) films to promote endothelialization, Bioconjug Chem., 16, 1088, 10.1021/bc049717s · doi:10.1021/bc049717s
  190. Co, 2005, Biocompatible micropatterning of two different cell types, J Am Chem Soc., 127, 1598, 10.1021/ja044382a · DOI
  191. Nakanishi, 2008, Recent advances in cell micropatterning techniques for bioanalytical and biomedical sciences, Anal Sci., 24, 67, 10.2116/analsci.24.67 · DOI

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Metadata

Authors
Novosel, E. C., Kleinhans, C., & Kluger, P. J.
Venue
Advanced Drug Delivery Reviews
Publisher
Elsevier BV
Published
2011-04
Volume
63
Issue
4-5
Pages
300-311
ISSN
0169-409X (ISSN-L)
OpenAlex
W2006431507
Cited by
1,062
References
6
FWCI
9.77
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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CoChat. (2026). Citation check: Vascularization is the key challenge in tissue engineering. https://app.cochat.ai/papers/10.1016/j.addr.2011.03.004
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Novosel, E. C., Kleinhans, C., & Kluger, P. J. (2011). Vascularization is the key challenge in tissue engineering. Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2011.03.004

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