The pharmacology of resveratrol in animals and humans

Cancer statistics, 2014

Siegel, R., Ma, J., Zou, Z., & Jemal, A. (2014) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21208 · Cited by 11,499 · see citing works

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

Jang, M., Cai, L., Udeani, G. O., Slowing, K. V., Thomas, C. F., Beecher, C. W. W., Fong, H. H. S., Farnsworth, N. R., Kinghorn, A. D., Mehta, R. G., et al. (1997) · Science · doi:10.1126/science.275.5297.218 · Cited by 4,935 · see citing works

Wine, alcohol, platelets, and the French paradox for coronary heart disease

Renaud, S., & de Lorgeril, M. (1992) · The Lancet · doi:10.1016/0140-6736(92)91277-f · Cited by 3,654 · see citing works

SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function

Price, N. L., Gomes, A. P., Ling, A. J. Y., Duarte, F. V., Martin-Montalvo, A., North, B. J., Agarwal, B., Ye, L., Ramadori, G., Teodoro, J. S., et al. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.04.003 · Cited by 1,602 · see citing works

Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

Timmers, S., Konings, E., Bilet, L., Houtkooper, R. H., van de Weijer, T., Goossens, G. H., Hoeks, J., van der Krieken, S., Ryu, D., Kersten, S., et al. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.10.002 · Cited by 1,320 · see citing works

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

Miller, R. A., Harrison, D. E., Astle, C. M., Baur, J. A., Boyd, A. R., de Cabo, R., Fernandez, E., Flurkey, K., Javors, M. A., Nelson, J. F., et al. (2011) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glq178 · Cited by 896 · see citing works

Concentration of the Phytoalexin Resveratrol in Wine

Siemann, E. H., & Creasy, L. L. (1992) · American Journal of Enology and Viticulture · doi:10.5344/ajev.1992.43.1.49 · Cited by 719 · see citing works

Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients

Brasnyó, P., Molnár, G. A., Mohás, M., Markó, L., Laczy, B., Cseh, J., Mikolás, E., Szijártó, I. A., Mérei, Á., Halmai, R., et al. (2011) · British Journal Of Nutrition · doi:10.1017/s0007114511000316 · Cited by 680 · see citing works

AMP-activated Protein Kinase Signaling Activation by Resveratrol Modulates Amyloid-β Peptide Metabolism

Vingtdeux, V., Giliberto, L., Zhao, H., Chandakkar, P., Wu, Q., Simon, J. E., Janle, E. M., Lobo, J., Ferruzzi, M. G., Davies, P. J., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.060061 · Cited by 648 · see citing works

AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol

Um, J.-H., Park, S.-J., Kang, H., Yang, S., Foretz, M., McBurney, M. W., Kim, M. K., Viollet, B., & Chung, J. H. (2010) · Diabetes · doi:10.2337/db09-0482 · Cited by 647 · see citing works

Clinical Pharmacology of Resveratrol and Its Metabolites in Colorectal Cancer Patients

Patel, K. R., Brown, V. A., Jones, D. J. L., Britton, R. G., Hemingway, D., Miller, A. S., West, K., Booth, T. D., Perloff, M., Crowell, J. A., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-10-2027 · Cited by 629 · see citing works

Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2

Ungvari, Z. I., Bagi, Z. A., Fehér, A., Recchia, F. A., Sonntag, W. E., Pearson, K. J., de Cabo, R., & Csiszár, A. (2010) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00260.2010 · Cited by 571 · see citing works

Diabetes, oxidative stress and therapeutic strategies

Rochette, L., Zeller, M., Cottin, Y., & Vergely, C. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.05.017 · Cited by 530 · see citing works

Animal Models of Depression: Molecular Perspectives

Krishnan, V., & Nestler, E. J. (2011) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2010_108 · Cited by 528 · see citing works

Classic and New Animal Models of Parkinson's Disease

Blesa, J., Phani, S., Jackson-Lewis, V. R., & Przedborski, S. (2012) · BioMed Research International · doi:10.1155/2012/845618 · Cited by 502 · see citing works

Resveratrol supplementation improves glycemic control in type 2 diabetes mellitus

Bhatt, J. K., Thomas, S., & Nanjan, M. J. (2012) · Nutrition Research · doi:10.1016/j.nutres.2012.06.003 · Cited by 475 · see citing works

High-Dose Resveratrol Supplementation in Obese Men

Poulsen, M. M., Vestergaard, P. F., Clasen, B. F., Radko, Y., Christensen, L. P., Stødkilde-Jørgensen, H., Møller, N., Jessen, N., Pedersen, S. B., & Jørgensen, J. O. L. (2013) · Diabetes · doi:10.2337/db12-0975 · Cited by 455 · see citing works

Effects of Resveratrol on Memory Performance, Hippocampal Functional Connectivity, and Glucose Metabolism in Healthy Older Adults

Witte, A. V., Kerti, L., Margulies, D. S., & Floel, A. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0385-14.2014 · Cited by 455 · see citing works

Phase I Randomized, Double-Blind Pilot Study of Micronized Resveratrol (SRT501) in Patients with Hepatic Metastases—Safety, Pharmacokinetics, and Pharmacodynamics

Howells, L. M., Berry, D. P., Elliott, P. J., Jacobson, E. W., Hoffmann, E. C., Hegarty, B., Brown, K., Steward, W. P., & Gescher, A. J. (2011) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-11-0148 · Cited by 447 · see citing works

Suppression of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in rats by resveratrol: role of nuclear factor-kappaB, cyclooxygenase 2, and matrix metalloprotease 9.

Banerjee, S., Bueso-Ramos, C., & Aggarwal, B. B. (2002) · PubMed · Cited by 423 · see citing works

Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation

Kennedy, D. O., Wightman, E. L., Reay, J. L., Lietz, G., Okello, E. J., Wilde, A., & Haskell, C. F. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28641 · Cited by 415 · see citing works

Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats

Su, H., Hung, L., & Chen, J.-K. (2006) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00487.2005 · Cited by 410 · see citing works

Inhibition of cancer growth by resveratrol is related to its low bioavailability

Asensi, M., Medina, I., Ortega, A., Carretero, J., Baño, M. C., Obrador, E., & Estrela, J. M. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00911-5 · Cited by 388 · see citing works

Resveratrol Supplementation Does Not Improve Metabolic Function in Nonobese Women with Normal Glucose Tolerance

Yoshino, J., Conte, C., Fontana, L., Mittendorfer, B., Imai, S., Schechtman, K. B., Gu, C. C., Kunz, I., Fanelli, F. R., Patterson, B. W., et al. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.09.015 · Cited by 381 · see citing works

Resveratrol protects diabetic kidney by attenuating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via Nrf2–Keap1 signaling

Periyasamy, P., & Subramanian, S. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2011.03.008 · Cited by 380 · see citing works

One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease

Tomé‐Carneiro, J., Larrosa, M., Yáñez-Gascón, M. J., Dávalos, A., Gil‐Zamorano, J., Gonzálvez, M., García‐Almagro, F. J., Ros, J. A. R., Tomás-Barberán, F. A., Espı́n, J. C., et al. (2013) · Pharmacological Research · doi:10.1016/j.phrs.2013.03.011 · Cited by 378 · see citing works

Animal models of disease: Pre-clinical animal models of cancer and their applications and utility in drug discovery

Ruggeri, B., Camp, F., & Miknyoczki, S. J. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.06.020 · Cited by 369 · see citing works

Effects of resveratrol on gut microbiota and fat storage in a mouse model with high-fat-induced obesity

Qiao, Y., Sun, J., Xia, S., Tang, X., Shi, Y., & Le, G. (2014) · Food & Function · doi:10.1039/c3fo60630a · Cited by 367 · see citing works

Cardioprotection by resveratrol: A human clinical trial in patients with stable coronary artery disease

Magyar, K., Halmosi, R., Pálfi, A., Fehér, G., Czopf, L., Fulop, A., Battyány, I., Sümegi, B., Tóth, K., & Szabados, E. (2012) · Clinical Hemorheology and Microcirculation · doi:10.3233/ch-2011-1424 · Cited by 364 · see citing works

Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats

Sinha, K., Chaudhary, G., & Gupta, Y. K. (2002) · Life Sciences · doi:10.1016/s0024-3205(02)01691-0 · Cited by 356 · see citing works

Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice

Narayanan, N. K., Nargi, D., Randolph, C., & Narayanan, B. A. (2009) · International Journal of Cancer · doi:10.1002/ijc.24336 · Cited by 353 · see citing works

Resveratrol Attenuates Obesity-Associated Peripheral and Central Inflammation and Improves Memory Deficit in Mice Fed a High-Fat Diet

Jeon, B. T., Jeong, E. A., Shin, H. J., Lee, Y., Lee, D. H., Kim, H. J., Kang, S. S., Cho, G. J., Choi, W. S., & Roh, G. S. (2012) · Diabetes · doi:10.2337/db11-1498 · Cited by 352 · see citing works

Resveratrol induces apoptosis and inhibits angiogenesis in human breast cancer xenografts in vivo

Garvin, S., Öllinger, K. M., & Dabrosin, C. (2005) · Cancer Letters · doi:10.1016/j.canlet.2005.01.031 · Cited by 351 · see citing works

Enhancing the bioavailability of resveratrol by combining it with piperine

Johnson, J. J., Nihal, M., Siddiqui, I. A., Scarlett, C. O., Bailey, H. H., Mukhtar, H., & Ahmad, N. (2011) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201100117 · Cited by 340 · see citing works

Resveratrol Modulates Drug- and Carcinogen-Metabolizing Enzymes in a Healthy Volunteer Study

Chow, H. ‐. S., Garland, L. L., Hsu, C., Vining, D. R., Chew, W. M., Miller, J. A., Perloff, M., Crowell, J. A., & Alberts, D. S. (2010) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-09-0155 · Cited by 333 · see citing works

Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models.

Bhat, K., Lantvit, D. D., Christov, K. T., Mehta, R. G., Moon, R. C., & Pezzuto, J. M. (2001) · PubMed · Cited by 330 · see citing works

Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease

Mudó, G., Mäkelä, J., Liberto, V. D., Tselykh, T. V., Olivieri, M., Piepponen, P., Eriksson, O., Mälkiä, A., Bonomo, A., Kairisalo, M., et al. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0850-z · Cited by 315 · see citing works

Resveratrol Isolated from Polygonum cuspidatum Root Prevents Tumor Growth and Metastasis to Lung and Tumor-Induced Neovascularization in Lewis Lung Carcinoma-Bearing Mice

Kimura, Y., & Okuda, H. (2001) · Journal of Nutrition · doi:10.1093/jn/131.6.1844 · Cited by 311 · see citing works

Resveratrol Inhibits Breast Cancer Stem-Like Cells and Induces Autophagy via Suppressing Wnt/β-Catenin Signaling Pathway

Fu, Y., Chang, H., Peng, X., Bai, Q., Yi, L., Zhou, Y. G., Zhu, J., & Mi, M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102535 · Cited by 300 · see citing works

Anti-Inflammatory Effects of Resveratrol, Curcumin and Simvastatin in Acute Small Intestinal Inflammation

Bereswill, S., Muñoz, M., Fischer, A., Plickert, R., Haag, L.-M., Otto, B., Kühl, A. A., Loddenkemper, C., Göbel, U. B., & Heimesaat, M. M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015099 · Cited by 290 · see citing works

Resveratrol protects against age-associated infertility in mice

Liu, M., Yin, Y., Ye, X., Zeng, M., Zhao, Q., Keefe, D. L., & Liu, L. (2013) · Human Reproduction · doi:10.1093/humrep/des437 · Cited by 289 · see citing works

Resveratrol, an activator of SIRT1, upregulates sarcoplasmic calcium ATPase and improves cardiac function in diabetic cardiomyopathy

Sulaiman, M., Matta, M., Sunderesan, N. R., Gupta, M. P., Periasamy, M., & Gupta, M. P. (2009) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00418.2009 · Cited by 286 · see citing works

Pilot study of resveratrol in older adults with impaired glucose tolerance

Crandall, J. P., Oram, V., Trandafirescu, G., Reid, M., Kishore, P., Hawkins, M., Cohen, H. W., & Barzilai, N. (2012) · The Journals of Gerontology: Series A · doi:10.1093/gerona/glr235 · Cited by 281 · see citing works

Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21CIP expression

Tessitore, L., Davit, A., Sarotto, I., & Caderni, G. (2000) · Carcinogenesis · doi:10.1093/carcin/21.5.619 · Cited by 281 · see citing works

Resveratrol attenuates 6-hydroxydopamine-induced oxidative damage and dopamine depletion in rat model of Parkinson's disease

Khan, M. M., Ahmad, A., Ishrat, T., Khan, M. B., Hoda, M. N., Khuwaja, G., Raza, S. S., Khan, A., Javed, H., Vaibhav, K., et al. (2010) · Brain Research · doi:10.1016/j.brainres.2010.02.031 · Cited by 279 · see citing works

Acute resveratrol supplementation improves flow-mediated dilatation in overweight/obese individuals with mildly elevated blood pressure

Wong, R. H. X., Howe, P. R. C., Buckley, J. D., Coates, A. M., Kunz, I., & Berry, N. M. (2011) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2010.03.003 · Cited by 277 · see citing works

Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase

Thirunavukkarasu, M., Penumathsa, S. V., Koneru, S., Juhász, B., Zhan, L., Otani, H., Bagchi, D., Das, D. K., & Maulik, N. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.05.004 · Cited by 271 · see citing works

Dietary resveratrol prevents Alzheimer’s markers and increases life span in SAMP8

Porquet, D., Casadesús, G., Bayod, S., Vicente, A., Canudas, A. M., Vilaplana, J., Pelegrı́, C., Sanfeliu, C., Camins, A., Pallàs, M., et al. (2012) · AGE · doi:10.1007/s11357-012-9489-4 · Cited by 268 · see citing works

Prevention of short-term ultraviolet B radiation-mediated damages by resveratrol in SKH-1 hairless mice☆☆Part of this work was conducted at the Department of Dermatology, Case Western Reserve University and the Research Institute of University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, Ohio 44106.

Afaq, F., Adhami, V. M., & Ahmad, N. (2003) · Toxicology and Applied Pharmacology · doi:10.1016/s0041-008x(02)00014-5 · Cited by 262 · see citing works

One-Year Consumption of a Grape Nutraceutical Containing Resveratrol Improves the Inflammatory and Fibrinolytic Status of Patients in Primary Prevention of Cardiovascular Disease

Tomé‐Carneiro, J., Gonzálvez, M., Larrosa, M., Yáñez-Gascón, M. J., García‐Almagro, F. J., Ruiz‐Ros, J. A., García‐Conesa, M., Tomás-Barberán, F. A., & Espı́n, J. C. (2012) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2012.03.030 · Cited by 260 · see citing works

Antihyperglycemic Effects of Short Term Resveratrol Supplementation in Type 2 Diabetic Patients

Movahed, A., Nabipour, I., Louis, X. L., Thandapilly, S. J., Yu, L., Kalantarhormozi, M., Rekabpour, S. J., & Netticadan, T. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/851267 · Cited by 258 · see citing works

Resveratrol, a Natural Product Present in Wine, Decreases Tumour Growth in a Rat Tumour Model

Carbó, N., Costelli, P., Baccino, F. M., López-Soriano, F. J., & Argilés, J. M. A. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9916 · Cited by 255 · see citing works

A comparison of the anticarcinogenic properties of four red wine polyphenols

Soleas, G. J., Grass, L., Josephy, P. D., Goldberg, D. M., & Diamandis, E. P. (2002) · Clinical Biochemistry · doi:10.1016/s0009-9120(02)00275-8 · Cited by 251 · see citing works

Trans-Resveratrol Alters Mammary Promoter Hypermethylation in Women at Increased Risk for Breast Cancer

Zhu, W., Qin, W., Zhang, K., Rottinghaus, G. E., Chen, Y.-C., Kliethermes, B., & Sauter, E. R. (2012) · Nutrition and Cancer · doi:10.1080/01635581.2012.654926 · Cited by 244 · see citing works

Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men

Gliemann, L., Schmidt, J. F., Olesen, J., Biensø, R. S., Peronard, S. L., Grandjean, S. U., Mortensen, S. P., Nyberg, M., Bangsbo, J., Pilegaard, H., et al. (2013) · The Journal of Physiology · doi:10.1113/jphysiol.2013.258061 · Cited by 244 · see citing works

Grape Resveratrol Increases Serum Adiponectin and Downregulates Inflammatory Genes in Peripheral Blood Mononuclear Cells: A Triple-Blind, Placebo-Controlled, One-Year Clinical Trial in Patients with Stable Coronary Artery Disease

Tomé‐Carneiro, J., Gonzálvez, M., Larrosa, M., Yáñez-Gascón, M. J., García‐Almagro, F. J., Ruiz‐Ros, J. A., Tomás-Barberán, F. A., García‐Conesa, M., & Espı́n, J. C. (2012) · Cardiovascular Drugs and Therapy · doi:10.1007/s10557-012-6427-8 · Cited by 241 · see citing works

Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin-induced diabetic rats

Schmatz, R., Mazzanti, C. M. D. A., Spanevello, R. M., Stefanello, N., Gutierres, J. M., Corrêa, M., da Rosa, M. M., Rubin, M. A., Schetinger, M. R. C., & Morsch, V. M. (2009) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2009.03.032 · Cited by 241 · see citing works

Resveratrol Improves Adipose Insulin Signaling and Reduces the Inflammatory Response in Adipose Tissue of Rhesus Monkeys on High-Fat, High-Sugar Diet

Jiménez, Y., Mattison, J. A., Pearson, K. J., Martín‐Montalvo, A., Palacios, H. H., Sossong, A. M., Ward, T. M., Younts, C. M., Lewis, K. N., Allard, J. S., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.09.004 · Cited by 240 · see citing works

Chemopreventive effect of resveratrol, sesamol, sesame oil and sunflower oil in the Epstein-Barr virus early antigen activation assay and the mouse skin two-stage carcinogenesis

Kapadia, G. J., Azuine, M. A., Tokuda, H., Takasaki, M., Mukainaka, T., Konoshima, T., & Nishino, H. (2002) · Pharmacological Research · doi:10.1006/phrs.2002.0992 · Cited by 238 · see citing works

Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation

Lee, H., Zhang, P., Herrmann, A., Yang, C., Xin, H., Wang, Z., Hoon, D. S. �., Forman, S. J., Jove, R., Riggs, A. D., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1205132109 · Cited by 235 · see citing works

Animal Models of Huntington's Disease

Ramaswamy, S., McBride, J. L., & Kordower, J. H. (2007) · ILAR Journal · doi:10.1093/ilar.48.4.356 · Cited by 234 · see citing works

Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats

Virgili, M., & Contestabile, A. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)00820-x · Cited by 234 · see citing works

Brain protection by resveratrol and fenofibrate against stroke requires peroxisome proliferator-activated receptor α in mice

Inoue, H., Jiang, X., Katayama, T., Osada, S., Umesono, K., & Namura, S. (2003) · Neuroscience Letters · doi:10.1016/j.neulet.2003.09.001 · Cited by 232 · see citing works

Resveratrol Prevents the Prohypertrophic Effects of Oxidative Stress on LKB1

Dolinsky, V. W., Chan, A. Y. M., Frayne, I. R., Light, P. E., Rosiers, C. D., & Dyck, J. R. B. (2009) · Circulation · doi:10.1161/circulationaha.108.787440 · Cited by 232 · see citing works

Evaluation of Resveratrol, Green Tea Extract, Curcumin, Oxaloacetic Acid, and Medium-Chain Triglyceride Oil on Life Span of Genetically Heterogeneous Mice

Strong, R., Miller, R. A., Astle, C. M., Baur, J. A., de Cabo, R., Fernandez, E., Guo, W., Javors, M. A., Kirkland, J. L., Nelson, J. F., et al. (2012) · The Journals of Gerontology Series A · doi:10.1093/gerona/gls070 · Cited by 232 · see citing works

Grapes and Human Health: A Perspective

Pezzuto, J. M. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf800898p · Cited by 232 · see citing works

Resveratrol, a natural phytoalexin, normalizes hyperglycemia in streptozotocin-nicotinamide induced experimental diabetic rats

Periyasamy, P., & Subramanian, S. (2008) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2008.06.037 · Cited by 229 · see citing works

Resveratrol‐enhanced autophagic flux ameliorates myocardial oxidative stress injury in diabetic mice

Wang, B., Yang, Q., Sun, Y., Xing, Y., Wang, Y., Lu, X., Bai, W., Liu, X., & Zhao, Y. (2014) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.12312 · Cited by 228 · see citing works

Resveratrol Reduces Prostate Cancer Growth and Metastasis by Inhibiting the Akt/MicroRNA-21 Pathway

Sheth, S., Jajoo, S., Kaur, T., Mukherjea, D., Sheehan, K., Rybak, L. P., & Ramkumar, V. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051655 · Cited by 225 · see citing works

Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?

Aziz, M. H., Reagan‐Shaw, S., Wu, J., Longley, B. J., & Ahmad, N. (2005) · The FASEB Journal · doi:10.1096/fj.04-3582fje · Cited by 220 · see citing works

Resveratrol Suppresses Colitis and Colon Cancer Associated with Colitis

Cui, X., Yu, J. H., Hofseth, A. B., Peña, E. A., Habiger, J., Chumanevich, A. A., Poudyal, D., Nagarkatti, M., Nagarkatti, P. S., Singh, U. P., et al. (2010) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-09-0117 · Cited by 219 · see citing works

Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease

Chang, J., Rimando, A. M., Pallàs, M., Camins, A., Porquet, D., Reeves, J., Shukitt‐Hale, B., Smith, M. A., Joseph, J. A., & Casadesús, G. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.08.015 · Cited by 217 · see citing works

Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice

Sánchez‐Fidalgo, S., Cárdeno, A., Villegas, I., Talero, E., & Alarcón‐de‐la‐Lastra, C. (2010) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2010.01.025 · Cited by 217 · see citing works

Resveratrol Protects Rats from Aβ-induced Neurotoxicity by the Reduction of iNOS Expression and Lipid Peroxidation

Huang, T.-C., Lu, K., Wo, Y.-Y. P., Wu, Y.-J., & Yang, Y.-L. (2011) · PLoS ONE · doi:10.1371/journal.pone.0029102 · Cited by 217 · see citing works

Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

Chowdhury, S. R., Smith, D. R., Saleh, A. J., Schapansky, J., Marquez, A. M., Gomes, S., Akude, E., Morrow, D., Calcutt, N. A., & Fernyhough, P. (2012) · Brain · doi:10.1093/brain/aws097 · Cited by 215 · see citing works

Consumption of a grape extract supplement containing resveratrol decreases oxidized LDL and A po B in patients undergoing primary prevention of cardiovascular disease: A triple‐blind, 6‐month follow‐up, placebo‐controlled, randomized trial

Tomé‐Carneiro, J., Gonzálvez, M., Larrosa, M., García‐Almagro, F. J., Avilés-Plaza, F. V., Parra, S., Yáñez-Gascón, M. J., Ruiz‐Ros, J. A., García‐Conesa, M., Tomás-Barberán, F. A., et al. (2012) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201100673 · Cited by 211 · see citing works

Anti-Inflammatory and Antioxidant Effects of Resveratrol in Healthy Smokers A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial

Bo, S., Ciccone, G., Castiglione, A., Gambino, R., Michieli, F. D., Villois, P., Durazzo, M., Cavallo‐Perin, P., & Cassader, M. (2013) · Current Medicinal Chemistry · doi:10.2174/0929867311320100009 · Cited by 209 · see citing works

Resveratrol ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice

Zhang, H., Zhai, Z., Wang, Y., Zhang, J., Wu, H., Wang, Y., Li, C., Li, D., Lu, L., Wang, X., et al. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.10.530 · Cited by 207 · see citing works

Resveratrol prevents hypertension and cardiac hypertrophy in hypertensive rats and mice

Dolinsky, V. W., Chakrabarti, S., Pereira, T. J., Oka, T., Levasseur, J. L., Beker, D. L., Zordoky, B. N. M., Morton, J. S., Nagendran, J., Lopaschuk, G. D., et al. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2013.05.018 · Cited by 206 · see citing works

Resveratrol suppresses growth of cancer stem-like cells by inhibiting fatty acid synthase

Pandey, P. R., Okuda, H., Watabe, M., Pai, S. K., Liu, W., Kobayashi, A., Xing, F., Fukuda, K., Hirota, S., Sugai, T., et al. (2010) · Breast Cancer Research and Treatment · doi:10.1007/s10549-010-1300-6 · Cited by 205 · see citing works

Pterostilbene Is More Potent than Resveratrol in Preventing Azoxymethane (AOM)-Induced Colon Tumorigenesis via Activation of the NF-E2-Related Factor 2 (Nrf2)-Mediated Antioxidant Signaling Pathway

Chiou, Y.-S., Tsai, M.-L., Nagabhushanam, K., Wang, Y.-J., Wu, C., Ho, C., & Pan, M. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf2000103 · Cited by 205 · see citing works

Resveratrol Inhibits Intestinal Tumorigenesis and Modulates Host-Defense-Related Gene Expression in an Animal Model of Human Familial Adenomatous Polyposis

Schneider, Y., Duranton, B., Goss, F., Schleiffer, R., Seiler, N., & Raul, F. (2001) · Nutrition and Cancer · doi:10.1207/s15327914nc391_14 · Cited by 200 · see citing works

Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic β‐cell dysfunction in streptozotocin‐nicotinamide‐induced diabetic rats

Periyasamy, P., & Subramanian, S. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22138 · Cited by 199 · see citing works

Effects of resveratrol on nerve functions, oxidative stress and DNA fragmentation in experimental diabetic neuropathy

Kumar, A., Kaundal, R. K., Iyer, S. R., & Sharma, S. S. (2007) · Life Sciences · doi:10.1016/j.lfs.2006.12.036 · Cited by 196 · see citing works

Wine and Health: A Review

Guilford, J. M., & Pezzuto, J. M. (2011) · American Journal of Enology and Viticulture · doi:10.5344/ajev.2011.11013 · Cited by 191 · see citing works

Effects of resveratrol on biomarkers of oxidative stress and on the activity of delta aminolevulinic acid dehydratase in liver and kidney of streptozotocin-induced diabetic rats

Schmatz, R., Pereira, L. B., Stefanello, N., Mazzanti, C. M. D. A., Spanevello, R. M., Gutierres, J. M., Bagatini, M. D., Martins, C. C., Abdalla, F. H., Serres, J. D. D. S., et al. (2011) · Biochimie · doi:10.1016/j.biochi.2011.08.005 · Cited by 191 · see citing works

Antidepressant-like effect of trans-resveratrol: Involvement of serotonin and noradrenaline system

Xu, Y., Wang, Z., You, W., Zhang, X., Li, S., Barish, P. A., Vernon, M. M., Du, X., Li, G., & Pan, J. (2010) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2010.02.013 · Cited by 186 · see citing works

Resveratrol, a Polyphenolic Phytoalexin, Attenuates Diabetic Nephropathy in Rats

Sharma, S., Anjaneyulu, M., Kulkarni, S., & Chopra, K. (2005) · Pharmacology · doi:10.1159/000089720 · Cited by 177 · see citing works

Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway

Yong-na, Z., Li, W., Li, F. Y., Zhang, Z., Dai, Y.-D., Xu, A.-L., Cui, Q., Gao, J., & Gao, J. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.05.025 · Cited by 176 · see citing works

Resveratrol enhances GLUT‐4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium

Penumathsa, S. V., Thirunavukkarasu, M., Zhan, L., Maulik, G., Menon, V. P., Bagchi, D., & Maulik, N. (2008) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2008.00251.x · Cited by 175 · see citing works

Resveratrol, a natural aryl hydrocarbon receptor antagonist, protects lung from DNA damage and apoptosis caused by benzo[ a ]pyrene

Revel, A., Raanani, H., Younglai, E. V., Xu, J., Rogers, I. M., Han, R. N. N., Savouret, J., & Casper, R. F. (2003) · Journal of Applied Toxicology · doi:10.1002/jat.916 · Cited by 174 · see citing works

Effects of resveratrol alone or in combination with piperine on cerebral blood flow parameters and cognitive performance in human subjects: a randomised, double-blind, placebo-controlled, cross-over investigation

Wightman, E. L., Reay, J. L., Haskell‐Ramsay, C. F., Williamson, G., Dew, T. P., & Kennedy, D. O. (2014) · British Journal Of Nutrition · doi:10.1017/s0007114514000737 · Cited by 172 · see citing works

Mouse models for liver cancer

Bakiri, L., & Wagner, E. F. (2013) · Molecular Oncology · doi:10.1016/j.molonc.2013.01.005 · Cited by 172 · see citing works

Resveratrol Prevents the Development of Pathological Cardiac Hypertrophy and Contractile Dysfunction in the SHR Without Lowering Blood Pressure

Thandapilly, S. J., Wojciechowski, P. W., Behbahani, J., Louis, X. L., Yu, L., Juric, D., Kopilas, M. A., Anderson, H. D., & Netticadan, T. (2009) · American Journal of Hypertension · doi:10.1038/ajh.2009.228 · Cited by 172 · see citing works

Resveratrol Levels and All-Cause Mortality in Older Community-Dwelling Adults

Semba, R. D., Ferrucci, L., Bartali, B., Urpí-Sardà, M., Zamora‐Ros, R., Sun, K., Cherubini, A., Bandinelli, S., & Andrés‐Lacueva, C. (2014) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2014.1582 · Cited by 168 · see citing works

Resveratrol-mediated chemoprevention of diethylnitrosamine-initiated hepatocarcinogenesis: Inhibition of cell proliferation and induction of apoptosis

Bishayee, A., & Dhir, N. (2008) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2008.11.015 · Cited by 167 · see citing works

Resveratrol reduction of infarct size in Long-Evans rats subjected to focal cerebral ischemia

Huang, S. S., Tsai, M. C., Chih, C. L., Hung, L., & Tsai, S. K. (2001) · Life Sciences · doi:10.1016/s0024-3205(01)01195-x · Cited by 167 · see citing works

Resveratrol improves neuron protection and functional recovery in rat model of spinal cord injury

Liu, C., Shi, Z., Fan, L., Zhang, C., Wang, K., & Wang, B. (2010) · Brain Research · doi:10.1016/j.brainres.2010.11.061 · Cited by 167 · see citing works

Antidepressant effects of resveratrol in an animal model of depression

Hurley, L. L., Akinfiresoye, L. R., Kalejaiye, O., & Tizabi, Y. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.03.052 · Cited by 166 · see citing works

Resveratrol Engages AMPK to Attenuate ERK and mTOR Signaling in Sensory Neurons and Inhibits Incision-Induced Acute and Chronic Pain

Tillu, D. V., Melemedjian, O. K., Asiedu, M. N., Qu, N., Felice, M. D., Dussor, G. O., & Price, T. J. (2012) · Molecular Pain · doi:10.1186/1744-8069-8-5 · Cited by 165 · see citing works

Comparison of the effects of the chemopreventive agent resveratrol and its synthetic analog trans 3,4,5,4′‐tetramethoxystilbene (DMU‐212) on adenoma development in the ApcMin+ mouse and cyclooxygenase‐2 in human‐derived colon cancer cells

Sale, S., Tunstall, R. G., Ruparelia, K. C., Potter, G. A., Steward, W. P., & Gescher, A. J. (2005) · International Journal of Cancer · doi:10.1002/ijc.20884 · Cited by 165 · see citing works

Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21CIP expression

Tessitore, L., Davit, A., Sarotto, I., et al. (2000) · Carcinogenesis · doi:10.1093/carcin/21.8.1619 · Cited by 164 · see citing works

Resveratrol Increases Glucose Induced GLP-1 Secretion in Mice: A Mechanism which Contributes to the Glycemic Control

Dao, T.-M. A., Waget, A., Klopp, P., Sérino, M., Vachoux, C., Pechère, L., Drucker, D. J., Champion, S., Barthélemy, S., Barra, Y., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020700 · Cited by 163 · see citing works

Chronic resveratrol consumption improves brachial flow-mediated dilatation in healthy obese adults

Wong, R. H. X., Berry, N. M., Coates, A. M., Buckley, J. D., Bryan, J., Kunz, I., & Howe, P. R. C. (2013) · Journal of Hypertension · doi:10.1097/hjh.0b013e328362b9d6 · Cited by 162 · see citing works

Oral resveratrol and calcium fructoborate supplementation in subjects with stable angina pectoris: Effects on lipid profiles, inflammation markers, and quality of life

Militaru, C., Donoiu, I., Crăciun-Mirescu, A., Scorei, I. D., Bulearca, A. M., & Scorei, I. R. (2012) · Nutrition · doi:10.1016/j.nut.2012.07.006 · Cited by 161 · see citing works

Resveratrol Suppresses Oxidative Stress and Inflammatory Response in Diethylnitrosamine-Initiated Rat Hepatocarcinogenesis

Bishayee, A., Barnes, K. F., Bhatia, D., Darvesh, A. S., & Carroll, R. T. (2010) · Cancer Prevention Research · doi:10.1158/1940-6207.capr-09-0171 · Cited by 161 · see citing works

Resveratrol suppresses prostate cancer progression in transgenic mice

Harper, C., Patel, B. B., Wang, J., Arabshahi, A., Eltoum, I. A., & Lamartiniere, C. A. (2007) · Carcinogenesis · doi:10.1093/carcin/bgm144 · Cited by 160 · see citing works

Evaluation of butylated hydroxyanisole, myo-inositol, curcumin, esculetin, resveratrol and lycopene as inhibitors of benzo[a]pyrene plus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice

Hecht, S. S., Kenney, P. M. J., Wang, M., Trushin, N., Agarwal, S., Rao, A. V., & Upadhyaya, P. (1999) · Cancer Letters · doi:10.1016/s0304-3835(98)00326-7 · Cited by 159 · see citing works

Protective effect of trans-resveratrol against kainic acid-induced seizures and oxidative stress in rats

Gupta, Y. K., Briyal, S., & Chaudhary, G. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00663-3 · Cited by 158 · see citing works

Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin

Reagan‐Shaw, S., Afaq, F., Aziz, M. H., & Ahmad, N. (2004) · Oncogene · doi:10.1038/sj.onc.1207666 · Cited by 158 · see citing works

Phosphatidylinositol-3-kinase is involved in the antihyperglycemic effect induced by resveratrol in streptozotocin-induced diabetic rats

Chi, T.-C., Chen, W.-P., Chi, T.-L., Kuo, T., Lee, S., Cheng, J., & Su, M. (2007) · Life Sciences · doi:10.1016/j.lfs.2007.02.002 · Cited by 156 · see citing works

Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin–nicotinamide-induced diabetic rats

Periyasamy, P., & Subramanian, S. P. (2008) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2008.11.008 · Cited by 155 · see citing works

Advances in porcine genomics and proteomics--a toolbox for developing the pig as a model organism for molecular biomedical research

Bendixen, E., Danielsen, M., Larsen, K., & Bendixen, C. (2010) · Briefings in Functional Genomics · doi:10.1093/bfgp/elq004 · Cited by 155 · see citing works

Effects of resveratrol on 12-O-tetradecanoylphorbol-13-acetate-induced oxidative events and gene expression in mouse skin

Jang, M., & Pezzuto, J. M. (1998) · Cancer Letters · doi:10.1016/s0304-3835(98)00250-x · Cited by 150 · see citing works

Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease

Ho, D. J., Calingasan, N. Y., Wille, E. J., Dumont, M., & Beal, M. F. (2010) · Experimental Neurology · doi:10.1016/j.expneurol.2010.05.006 · Cited by 147 · see citing works

Resveratrol attenuates hyperglycemia-mediated oxidative stress, proinflammatory cytokines and protects hepatocytes ultrastructure in streptozotocin–nicotinamide-induced experimental diabetic rats

Periyasamy, P., Sivakumar, S., & Subramanian, S. (2010) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2010.03.028 · Cited by 145 · see citing works

Resveratrol neuroprotective effects during focal cerebral ischemia injury via nitric oxide mechanism in rats

Tsai, S.-K., Hung, L., Fu, Y.-T., Cheng, H., Nien, M.-W., Liu, H.-Y., Zhang, F. B.-Y., & Huang, S.-S. (2007) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2007.04.044 · Cited by 145 · see citing works

Hypolipidemic action of dietary resveratrol, a phytoalexin in grapes and red wine, in hepatoma-bearing rats

Miura, D., Miura, Y., & Yagasaki, K. (2003) · Life Sciences · doi:10.1016/s0024-3205(03)00469-7 · Cited by 145 · see citing works

Resveratrol Improves Survival, Hemodynamics and Energetics in a Rat Model of Hypertension Leading to Heart Failure

Rimbaud, S., Ruiz, M., Piquereau, J., Matéo, P., Fortin, D., Veksler, V., Garnier, A., & Ventura‐Clapier, R. (2011) · PLoS ONE · doi:10.1371/journal.pone.0026391 · Cited by 142 · see citing works

Protective Effect of Resveratrol against Kainate-induced Temporal Lobe Epilepsy in Rats

Wu, Z., Xu, Q., Zhang, L., Kong, D., Ma, R., & Wang, L. (2009) · Neurochemical Research · doi:10.1007/s11064-009-9920-0 · Cited by 140 · see citing works

Resveratrol Inhibits the Growth of Gastric Cancer by Inducing G1 Phase Arrest and Senescence in a Sirt1-Dependent Manner

Yang, Q., Wang, B., Zang, W., Wang, X., Liu, Z., Li, W., & Jia, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070627 · Cited by 139 · see citing works

Resveratrol for primary prevention of atherosclerosis: Clinical trial evidence for improved gene expression in vascular endothelium

Agarwal, B., Campen, M. J., Channell, M. M., Wherry, S. J., Varamini, B., Davis, J. G., Baur, J. A., & Smoliga, J. M. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.09.027 · Cited by 137 · see citing works

SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol

Boily, G., He, X. H., Pearce, B., Jardine, K. E., & McBurney, M. W. (2009) · Oncogene · doi:10.1038/onc.2009.147 · Cited by 136 · see citing works

Resveratrol Prevents β-Cell Dedifferentiation in Nonhuman Primates Given a High-Fat/High-Sugar Diet

Fiori, J. L., Shin, Y., Kim, W., Krzysik-Walker, S. M., González‐Mariscal, I., Carlson, O. D., Sanghvi, M., Moaddel, R., Farhang, K., Gadkaree, S. K., et al. (2013) · Diabetes · doi:10.2337/db13-0266 · Cited by 136 · see citing works

Resveratrol, but not EGCG, in the diet suppresses DMBA-induced mammary cancer in rats.

Whitsett, T. G., Carpenter, M., & Lamartiniere, C. A. (2006) · Journal of Carcinogenesis · doi:10.1186/1477-3163-5-15 · Cited by 135 · see citing works

Central nervous system protection by resveratrol in streptozotocin-induced diabetic rats

Ateş, Ö., Cayli, S. R., Yücel, N., Altınöz, E., Koçak, A., Durak, M. A., Türköz, Y., & Yoloğlu, S. (2007) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2005.12.010 · Cited by 135 · see citing works

Chemopreventive effect of trans -resveratrol - a phytoalexin against colonic aberrant crypt foci and cell proliferation in 1,2-dimethylhydrazine induced colon carcinogenesis

Murugan, S., Viswanathan, P., & Nalini, N. (2005) · Carcinogenesis · doi:10.1093/carcin/bgi286 · Cited by 135 · see citing works

Resveratrol enhances insulin secretion by blocking KATP and KV channels of beta cells

Chen, W., Chi, T.-C., Chuang, L., & Su, M. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.04.062 · Cited by 133 · see citing works

Both aerobic exercise and resveratrol supplementation attenuate doxorubicin-induced cardiac injury in mice

Dolinsky, V. W., Rogan, K. J., Sung, M. M., Zordoky, B. N., Haykowsky, M. J., Young, M. E., Jones, L. W., & Dyck, J. R. B. (2013) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00044.2013 · Cited by 133 · see citing works

MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol

Yu, Y.-H., Chen, H.-A., Chen, P.-S., Cheng, Y.-J., Hsu, W.-H., Chang, Y.-W., Chen, Y.-H., Jan, Y., Hsiao, M., Chang, T.-Y., et al. (2012) · Oncogene · doi:10.1038/onc.2012.74 · Cited by 132 · see citing works

Resveratrol Enhances Antitumor Activity of TRAIL in Prostate Cancer Xenografts through Activation of FOXO Transcription Factor

Ganapathy, S., Chen, Q., Singh, K. P., Shankar, S., & Srivastava, R. K. (2010) · PLoS ONE · doi:10.1371/journal.pone.0015627 · Cited by 130 · see citing works

Resveratrol Inhibits Growth of Orthotopic Pancreatic Tumors through Activation of FOXO Transcription Factors

Roy, S. K., Chen, Q., Fu, J., Shankar, S., & Srivastava, R. K. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025166 · Cited by 130 · see citing works

Protective effect of resveratrol derived from Polygonum cuspidatum and its liposomal form on nigral cells in Parkinsonian rats

Wang, Y., Xu, H., Fu, Q., Ma, R., & Xiang, J. (2011) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2011.02.025 · Cited by 129 · see citing works

Resveratrol reduces the elevated level of MMP-9 induced by cerebral ischemia–reperfusion in mice

Gao, D., Zhang, X., Jiang, X., Peng, Y., Huang, W., Cheng, G. S., & Song, L. (2005) · Life Sciences · doi:10.1016/j.lfs.2005.10.030 · Cited by 129 · see citing works

Resveratrol preserves cerebrovascular density and cognitive function in aging mice

Oomen, C. A. (2009) · Frontiers in Aging Neuroscience · doi:10.3389/neuro.24.004.2009 · Cited by 126 · see citing works

Protective effect of resveratrol against doxorubicin-induced cardiac toxicity and fibrosis in male experimental rats

Arafa, M. H., Mohammad, N. S., Atteia, H. H., & Abdel‐Aziz, H. R. (2014) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-014-0339-y · Cited by 125 · see citing works

Resveratrol Attenuates Ovariectomy-Induced Hypertension and Bone Loss in Stroke-Prone Spontaneously Hypertensive Rats.

MIZUTANI, K., Ikeda, K., Kawai, Y., & Yamori, Y. (2000) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.46.78 · Cited by 125 · see citing works

Central Administration of Resveratrol Improves Diet-Induced Diabetes

Ramadori, G., Gautron, L., Fujikawa, T., Vianna, C. R., Elmquist, J. K., & Coppari, R. (2009) · Endocrinology · doi:10.1210/en.2009-0528 · Cited by 125 · see citing works

Resveratrol retards progression of diabetic nephropathy through modulations of oxidative stress, proinflammatory cytokines, and AMP-activated protein kinase

Chang, C., Chang, C.-Y., Wu, Y.-T., Huang, J., Yen, T., & Hung, L. (2011) · Journal of Biomedical Science · doi:10.1186/1423-0127-18-47 · Cited by 125 · see citing works

Effect of resveratrol on the development of spontaneous mammary tumors in HER‐2/neu transgenic mice

Provinciali, M., Re, F., Donnini, A., Orlando, F., Bartozzi, B., Stasio, G. D., & Smorlesi, A. (2005) · International Journal of Cancer · doi:10.1002/ijc.20874 · Cited by 124 · see citing works

Resveratrol Suppresses Cancer Cell Glucose Uptake by Targeting Reactive Oxygen Species–Mediated Hypoxia-Inducible Factor-1α Activation

Jung, K., Lee, J. H., Quach, C. H. T., Paik, J.-Y., Oh, H., Park, J. W., Lee, E. J., Moon, S. H., & Lee, K.-H. (2013) · Journal of Nuclear Medicine · doi:10.2967/jnumed.112.115436 · Cited by 124 · see citing works

Resveratrol Prevents Light-Induced Retinal Degeneration via Suppressing Activator Protein-1 Activation

Kubota, S., Kurihara, T., Ebinuma, M., Kubota, M., Yuki, K., Sasaki, M., Noda, K., Ozawa, Y., Oike, Y., Ishida, S., et al. (2010) · American Journal Of Pathology · doi:10.2353/ajpath.2010.100098 · Cited by 124 · see citing works

Resveratrol Protects Against Neurotoxicity Induced by Kainic Acid

Wang, Q., Yu, S. O., Simonyi, Á., Rottinghaus, G. E., Sun, G. Y., & Sun, A. Y. (2004) · Neurochemical Research · doi:10.1007/s11064-004-6883-z · Cited by 123 · see citing works

Cognitive Performances Are Selectively Enhanced during Chronic Caloric Restriction or Resveratrol Supplementation in a Primate

Dal‐Pan, A., Pifferi, F., Marchal, J., Picq, J., & Aujard, F. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016581 · Cited by 123 · see citing works

Resveratrol prevents tumorigenesis in mouse model of Kras activated sporadic colorectal cancer by suppressing oncogenic Kras expression

Saud, S. M., Li, W., Morris, N. L., Matter, M. S., Colburn, N. H., Kim, Y. S., & Young, M. R. (2014) · Carcinogenesis · doi:10.1093/carcin/bgu209 · Cited by 120 · see citing works

Methylation and miRNA Effects of Resveratrol on Mammary Tumors vs. Normal Tissue

Qin, W., Zhang, K., Clarke, K., Weiland, T. L., & Sauter, E. R. (2014) · Nutrition and Cancer · doi:10.1080/01635581.2014.868910 · Cited by 118 · see citing works

Differential effects of resveratrol on androgen-responsive LNCaP human prostate cancer cells in vitro and in vivo

Wang, T.-C., Hudson, T., Wang, T.-C., Remsberg, C. M., Davies, N. M., Takahashi, Y., Kim, Y. S., Seifried, H. E., Vinyard, B. T., Perkins, S. N., et al. (2008) · Carcinogenesis · doi:10.1093/carcin/bgn131 · Cited by 118 · see citing works

Beneficial and cautionary outcomes of resveratrol supplementation in pregnant nonhuman primates

Roberts, V. H. J., Pound, L. D., Wesolowski, S. R., Gillingham, M. B., Thornburg, K. L. R., Friedman, J. E., Frias, A. E., & Grove, K. L. (2014) · The FASEB Journal · doi:10.1096/fj.13-245472 · Cited by 118 · see citing works

Effect of Resveratrol on Growth of 4T1 Breast Cancer Cells in Vitro and in Vivo

Bove, K., Lincoln, D. W., & Tsan, M. (2002) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2002.6554 · Cited by 117 · see citing works

Chronic Resveratrol Enhances Endothelium-Dependent Relaxation but Does Not Alter eNOS Levels in Aorta of Spontaneously Hypertensive Rats

Rush, J. W. E., Quadrilatero, J., Levy, A. S., & Ford, R. J. (2007) · Experimental Biology and Medicine · doi:10.3181/00379727-232-2320814 · Cited by 115 · see citing works

Resveratrol Improves Myocardial Perfusion in a Swine Model of Hypercholesterolemia and Chronic Myocardial Ischemia

Robich, M. P., Osipov, R. M., Nezafat, R., Feng, J., Clements, R., Bianchi, C. F., Boodhwani, M., Coady, M. A., Laham, R. J., & Sellke, F. W. (2010) · Circulation · doi:10.1161/circulationaha.109.920132 · Cited by 115 · see citing works

Effects of different doses of resveratrol on body fat and serum parameters in rats fed a hypercaloric diet

Macarulla, M. T., Alberdi, G., Gómez‐Zorita, S., Tueros, I., Bald, C., Rodríguez, V. M., Martínez, J. A., & Portillo, M. P. (2009) · Journal of Physiology and Biochemistry · doi:10.1007/bf03185932 · Cited by 114 · see citing works

Metabolic Engineering of Yeast and Plants for the Production of the Biologically Active Hydroxystilbene, Resveratrol

Jeandet, P., Delaunois, B., Aziz, A., Donnez, D., Vasserot, Y., Cordelier, S., & Courot, É. (2012) · BioMed Research International · doi:10.1155/2012/579089 · Cited by 114 · see citing works

Pharmacokinetics of drugs in rats with diabetes mellitus induced by alloxan or streptozocin: comparison with those in patients with type I diabetes mellitus

Lee, J. H., Yang, S., Oh, J. M., & Lee, M. G. (2010) · Journal of Pharmacy and Pharmacology · doi:10.1211/jpp.62.01.0001 · Cited by 113 · see citing works

Resveratrol attenuates ischemic brain damage in the delayed phase after stroke and induces messenger RNA and protein express for angiogenic factors

Dong, W., Li, N., Gao, D., Zhen, H., Zhang, X., & Li, F. (2008) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2008.04.007 · Cited by 112 · see citing works

Resveratrol Alleviates Endotoxin-Induced Myocardial Toxicity via the Nrf2 Transcription Factor

Hao, E., Lang, F., Chen, Y., Zhang, H., Cong, X. Y., Shen, X., & Su, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069452 · Cited by 108 · see citing works

Pterostilbene is equally potent as resveratrol in inhibiting 12-O-tetradecanoylphorbol-13-acetate activated NFκB, AP-1, COX-2, and iNOS in mouse epidermis

Cichocki, M., Paluszczak, J., Szaefer, H., Piechowiak, A., Rimando, A. M., & Baer‐Dubowska, W. (2008) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200700466 · Cited by 108 · see citing works

Resveratrol Promotes Foot Ulcer Size Reduction in Type 2 Diabetes Patients

Bashmakov, Y. K., Assaad-Khalil, S. H., Abou-Seif, M., Udumyan, R., Megallaa, M. H. Z., Rohoma, K. H., Zeitoun, M., & Petyaev, I. M. (2014) · ISRN Endocrinology · doi:10.1155/2014/816307 · Cited by 105 · see citing works

Antidepressant-like effect of trans-resveratrol in chronic stress model: Behavioral and neurochemical evidences

Yu, Y., Wang, R., Chen, C., Du, X., Ruan, L., Sun, J., Li, J., Zhang, L., O’Donnell, J. M., Pan, J., et al. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.10.018 · Cited by 105 · see citing works

Resveratrol-Containing Gel for the Treatment of Acne Vulgaris

Fabbrocini, G., Staibano, S., Rosa, G. D., Battimiello, V., Fardella, N., Ilardi, G., Rotonda, M. I. L., Longobardi, A., Mazzella, M., Siano, M., et al. (2011) · American Journal of Clinical Dermatology · doi:10.2165/11530630-000000000-00000 · Cited by 104 · see citing works

The Effects of Chronic Resveratrol Treatment on Vascular Responsiveness of Streptozotocin-Induced Diabetic Rats

Sılan, C. (2008) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.31.897 · Cited by 104 · see citing works

Resveratrol prevents the development of abdominal aortic aneurysm through attenuation of inflammation, oxidative stress, and neovascularization

Kaneko, H., Anzai, T., Morisawa, M., Kohno, T., Nagai, T., Anzai, A., Takahashi, T., Shimoda, M., Sasaki, A., Maekawa, Y., et al. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.03.042 · Cited by 104 · see citing works

Resveratrol prevents alcohol-induced cognitive deficits and brain damage by blocking inflammatory signaling and cell death cascade in neonatal rat brain

Tiwari, V., & Chopra, K. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07236.x · Cited by 103 · see citing works

Resveratrol improves insulin signaling in a tissue-specific manner under insulin-resistant conditions only: in vitro and in vivo experiments in rodents

Kang, W., Hong, H. J., Guan, J., Kim, D. G., Yang, E.-J., Koh, G., Park, D.-B., Han, C. H., Lee, Y. J., & Lee, D.-H. (2011) · Metabolism · doi:10.1016/j.metabol.2011.08.003 · Cited by 103 · see citing works

Resveratrol Is Rapidly Metabolized in Athymic (Nu/Nu) Mice and Does Not Inhibit Human Melanoma Xenograft Tumor Growth

Niles, R. M., Cook, C. P., Meadows, G. G., Fu, Y., McLaughlin, J. L., & Rankin, G. O. (2006) · Journal of Nutrition · doi:10.1093/jn/136.10.2542 · Cited by 103 · see citing works

Pathology of Rodent Models of Intestinal Cancer: Progress Report and Recommendations

Washington, M. K., Powell, A. E., Sullivan, R., Sundberg, J. P., Wright, N., Coffey, R. J., & Dove, W. F. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.01.067 · Cited by 102 · see citing works

Impairment of tumor‐initiating stem‐like property and reversal of epithelial–mesenchymal transdifferentiation in head and neck cancer by resveratrol treatment

Hu, F., Tsai, L., Yu, C., Chen, P., Chou, M., & Yu, C. (2012) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201200150 · Cited by 102 · see citing works

Resveratrol Restores Nrf2 Level and Prevents Ethanol-Induced Toxic Effects in the Cerebellum of a Rodent Model of Fetal Alcohol Spectrum Disorders

Kumar, A., Singh, C. K., LaVoie, H. A., DiPette, D. J., & Singh, U. S. (2011) · Molecular Pharmacology · doi:10.1124/mol.111.071126 · Cited by 102 · see citing works

High-dose resveratrol treatment for 2 weeks inhibits intestinal and hepatic lipoprotein production in overweight/obese men

Dash, S., Xiao, C., Morgantini, C., Szeto, L., & Lewis, G. F. (2013) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/atvbaha.113.302342 · Cited by 102 · see citing works

Modulatory influence of dietary resveratrol during different phases of 1,2-dimethylhydrazine induced mucosal lipid-peroxidation, antioxidant status and aberrant crypt foci development in rat colon carcinogenesis

Sengottuvelan, M., Senthilkumar, R., & Nalini, N. (2006) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2006.03.008 · Cited by 100 · see citing works

Protective Effect Of Resveratrol On Oxidative Damage In Male And Female Stroke‐Prone Spontaneously Hypertensive Rats

Mizutani, K., Ikeda, K., Kawai, Y., & Yamori, Y. (2001) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.2001.03415.x · Cited by 100 · see citing works

Pterostilbene Acts through Metastasis-Associated Protein 1 to Inhibit Tumor Growth, Progression and Metastasis in Prostate Cancer

Li, K., Dias, S. J., Rimando, A. M., Dhar, S., Mizuno, C. S., Penman, A. D., Lewin, J. R., & Levenson, A. S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0057542 · Cited by 98 · see citing works

Genistein and resveratrol, alone and in combination, suppress prostate cancer in SV‐40 tag rats

Harper, C. E., Cook, L. M., Patel, B. B., Wang, J., Eltoum, I. A., Arabshahi, A., Shirai, T., & Lamartiniere, C. A. (2009) · The Prostate · doi:10.1002/pros.21017 · Cited by 98 · see citing works

Beneficial effects of resveratrol on scopolamine but not mecamylamine induced memory impairment in the passive avoidance and Morris water maze tests in rats

Gacar, N., Mutlu, O., Utkan, T., Celikyurt, I. K., Göçmez, S. S., & Ulak, G. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.05.017 · Cited by 98 · see citing works

Effect of resveratrol on cartilage protection and apoptosis inhibition in experimental osteoarthritis of rabbit

Wang, J., Gao, J., Chen, J., Li, F., & Tian, J. (2011) · Rheumatology International · doi:10.1007/s00296-010-1720-y · Cited by 97 · see citing works

Dietary supplementation of resveratrol suppresses colonic tumour incidence in 1,2-dimethylhydrazine-treated rats by modulating biotransforming enzymes and aberrant crypt foci development

Murugan, S., & Nalini, N. (2006) · British Journal Of Nutrition · doi:10.1079/bjn20061789 · Cited by 97 · see citing works

Trans- but Not Cis-Resveratrol Impairs Angiotensin-II–Mediated Vascular Inflammation through Inhibition of NF-κB Activation and Peroxisome Proliferator-Activated Receptor-γ Upregulation

Rius, C., Abu-Taha, M. I., Hermenegildo, C., Piqueras, L., Cerdá‐Nicolás, M., Issekutz, A. C., Estañ, L., Cortijo, J., Morcillo, E. J., Orallo, F., et al. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1001043 · Cited by 96 · see citing works

Therapeutic effects of resveratrol during acute periods following experimental ischemic stroke

Shin, J. A., Lee, H.-A., Lim, Y.-K., Koh, Y., Choi, J. H., & Park, E. (2010) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2010.06.017 · Cited by 95 · see citing works

Resveratrol prevents oxidative stress and inhibition of Na+K+-ATPase activity induced by transient global cerebral ischemia in rats

Simão, F., Matté, A., Matté, C., Soares, F. M. S., Wyse, Â. T. D. S., Netto, C. A., & Salbego, C. G. (2011) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2010.07.013 · Cited by 94 · see citing works

Resveratrol increases anti-aging Klotho gene expression via the activating transcription factor 3/c-Jun complex-mediated signaling pathway

Hsu, S.-C., Huang, S., Chen, A., Sun, C.-Y., Lin, S., Chen, J., Liu, S., & Hsu, Y. (2014) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2014.06.002 · Cited by 94 · see citing works

Neurodegeneration in Streptozotocin-Induced Diabetic Rats Is Attenuated by Treatment with Resveratrol

Jing, Y., Chen, K., Kuo, P., Pao, C.-C., & Chen, J. (2013) · Neuroendocrinology · doi:10.1159/000350435 · Cited by 93 · see citing works

The effect of resveratrol on FoxO1 expression in kidneys of diabetic nephropathy rats

Wu, L., Zhang, Y., Ma, X., Zhang, N., & Qin, G.-J. (2012) · Molecular Biology Reports · doi:10.1007/s11033-012-1780-z · Cited by 92 · see citing works

Resveratrol Inhibits the Proliferation of Neural Progenitor Cells and Hippocampal Neurogenesis

Park, H. R., Kong, K. H., Yu, B. P., Mattson, M. P., & Lee, J. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.406413 · Cited by 92 · see citing works

Suppression of prostate cancer growth by resveratrol in the transgenic rat for adenocarcinoma of prostate (TRAP) model.

Seeni, A., Takahashi, S., Takeshita, K., Tang, M., Sugiura, S., Sato, S., & Shirai, T. (2008) · PubMed · Cited by 92 · see citing works

Resveratrol Inhibits CD4+ T Cell Activation by Enhancing the Expression and Activity of Sirt1

Zou, T., Yang, Y., Xia, F., Huang, A., Gao, X., Fang, D., Xiong, S., & Zhang, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075139 · Cited by 91 · see citing works

Potent inhibition of Lewis lung cancer growth by heyneanol A from the roots of Vitis amurensis through apoptotic and anti-angiogenic activities

Lee, E. O. (2006) · Carcinogenesis · doi:10.1093/carcin/bgl055 · Cited by 91 · see citing works

Effect of Resveratrol on Oxidative and Inflammatory Stress in Liver and Spleen of Streptozotocin-Induced Type 1 Diabetic Rats

Chang, C. (2012) · The Chinese Journal of Physiology · doi:10.4077/cjp.2012.baa012 · Cited by 91 · see citing works

Inhibitory Effects of Resveratrol on Melanin Synthesis in Ultraviolet B-Induced Pigmentation in Guinea Pig Skin

Lee, T. H., Seo, J. O., Baek, S.-H., & Kim, S. Y. (2014) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2013.081 · Cited by 89 · see citing works

Resveratrol abrogates alcohol-induced cognitive deficits by attenuating oxidative–nitrosative stress and inflammatory cascade in the adult rat brain

Tiwari, V., & Chopra, K. (2013) · Neurochemistry International · doi:10.1016/j.neuint.2013.02.012 · Cited by 89 · see citing works

Effect of resveratrol, a polyphenolic phytoalexin, on thermal hyperalgesia in a mouse model of diabetic neuropathic pain

Sharma, S., Kulkarni, S. K., & Chopra, K. (2006) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2006.00455.x · Cited by 88 · see citing works

Resveratrol decreases fructose‐induced oxidative stress, mediated by NADPH oxidase via an AMPK ‐dependent mechanism

Cheng, P., Ho, W., Su, Y., Lu, P., Chen, B., Cheng, W., Lu, W., Sun, G., Yeh, T., Hsiao, M., et al. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12648 · Cited by 87 · see citing works

Resveratrol prevents impaired cognition induced by chronic unpredictable mild stress in rats

Liu, D., Zhang, Q., Gu, J., Wang, X., Xie, K., Xian, X., Wang, J., Jiang, H., & Wang, Z. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.10.017 · Cited by 87 · see citing works

Advantages of the association of resveratrol with oral contraceptives for management of endometriosis-related pain

Maia, H., Haddad, Pinheiro, & Casoy, J. (2012) · International Journal of Women s Health · doi:10.2147/ijwh.s36825 · Cited by 87 · see citing works

Antidepressant-like activity of resveratrol treatment in the forced swim test and tail suspension test in mice: The HPA axis, BDNF expression and phosphorylation of ERK

Wang, Z., Gu, J., Wang, X., Xie, K., Luan, Q., Wan, N., Zhang, Q., Jiang, H., & Liu, D. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2013.10.007 · Cited by 85 · see citing works

Endoplasmic Reticulum Stress in Retinal Vascular Degeneration: Protective Role of Resveratrol

Li, C., Wang, L., Huang, K., & Zheng, L. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.11-8406 · Cited by 85 · see citing works

Cerebroprotective effect of resveratrol through antioxidant and anti-inflammatory effects in diabetic rats

Orsu, P. (2013) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-013-0871-2 · Cited by 85 · see citing works

Fluorogenic Resveratrol-Confined Graphene Oxide For Economic and Rapid Detection Of Alzheimer’s Disease

He, X., Deng, Q., Cai, L., Wang, C.-Z., Zang, Y., Li, J. X., Chen, G., & Tian, H. (2014) · ACS Applied Materials & Interfaces · doi:10.1021/am5010909 · Cited by 84 · see citing works

Resveratrol: A Double-Edged Sword in Health Benefits

Salehi, B., Mishra, A. P., Nigam, M., Şener, B., Kılıç, M., Sharifi‐Rad, M., Fokou, P. V. T., Martins, N. A., & Sharifi‐Rad, J. (2018) · Biomedicines · doi:10.3390/biomedicines6030091 · Cited by 1,141 · see citing works

Polyphenols: Extraction Methods, Antioxidative Action, Bioavailability and Anticarcinogenic Effects

Brglez Mojzer, E., Knez Hrnčič, M., Škerget, M., Knez, Ž., & Bren, U. (2016) · Molecules · doi:10.3390/molecules21070901 · Cited by 1,096 · see citing works

Natural Products as a Vital Source for the Discovery of Cancer Chemotherapeutic and Chemopreventive Agents

Cragg, G. M. L., & Pezzuto, J. M. (2015) · Medical Principles and Practice · doi:10.1159/000443404 · Cited by 807 · see citing works

Resveratrol (RV): A pharmacological review and call for further research

Zhang, L., Li, C., Kakar, M. U., Khan, M. S., Wu, P.-F., Amir, R. M., Dai, D., Naveed, M., Li, Q., Saeed, M., et al. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112164 · Cited by 552 · see citing works

Nutrition, physical activity, and other lifestyle factors in the prevention of cognitive decline and dementia

Dominguez, L. J., Veronese, N., Vernuccio, L., Catanese, G., Inzerillo, F., Salemi, G., & Barbagallo, M. (2021) · Nutrients · doi:10.3390/nu13114080 · Cited by 433 · see citing works

Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies

Musso, G., Cassader, M., & Gambino, R. (2016) · Nature Reviews Drug Discovery · doi:10.1038/nrd.2015.3 · Cited by 415 · see citing works

Neuroprotective Mechanisms of Resveratrol in Alzheimer’s Disease: Role of SIRT1

Gomes, B. A. Q., Silva, J. P. B., Romeiro, C. F. R., dos Santos, S. M., Rodrigues, C. A., Gonçalves, P. R., Sakai, J. T., Mendes, P. F. S., Varela, E. L. P., & Monteiro, M. C. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/8152373 · Cited by 403 · see citing works

Autophagy as a molecular target for cancer treatment

Kocatürk, N. M., Akkoç, Y., Kığ, C., Bayraktar, O., Gözüaçık, D., & Kutlu, Ö. (2019) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2019.04.011 · Cited by 388 · see citing works

Polymeric Nanoparticles for Delivery of Natural Bioactive Agents: Recent Advances and Challenges

Elmowafy, M., Shalaby, K., Elkomy, M. H., Alsaidan, O. A., Gomaa, H. A. M., Abdelgawad, M. A., & Mostafa, E. M. (2023) · Polymers · doi:10.3390/polym15051123 · Cited by 341 · see citing works

Resveratrol and Its Effects on the Vascular System

Breuss, J. M., Atanasov, A. G., & Uhrín, P. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20071523 · Cited by 328 · see citing works

Skin aging and oxidative stress: Equol’s anti-aging effects via biochemical and molecular mechanisms

Lephart, E. D. (2016) · Ageing Research Reviews · doi:10.1016/j.arr.2016.08.001 · Cited by 325 · see citing works

Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer

Xu, J., Liu, D., Niu, H., Zhu, G., Xu, Y., Ye, D., Li, J., & Zhang, Q. (2017) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-016-0487-8 · Cited by 285 · see citing works

Antidiabetic Properties of Naringenin: A Citrus Fruit Polyphenol

Hartogh, D. J. D., & Tsiani, E. (2019) · Biomolecules · doi:10.3390/biom9030099 · Cited by 269 · see citing works

An Overview of Herbal Products and Secondary Metabolites Used for Management of Type Two Diabetes

Ota, A., & Ulrih, N. P. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00436 · Cited by 218 · see citing works

Resveratrol and Vascular Function

Li, H., Xia, N., Hasselwander, S., & Daiber, A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20092155 · Cited by 204 · see citing works

Resveratrol‐loaded nanomedicines for cancer applications

Annaji, M., Poudel, I., Boddu, S. H. S., Arnold, R. D., Tiwari, A. K., & Babu, R. J. (2021) · Cancer Reports · doi:10.1002/cnr2.1353 · Cited by 202 · see citing works

Hop Compounds: Extraction Techniques, Chemical Analyses, Antioxidative, Antimicrobial, and Anticarcinogenic Effects

Hrnčič, M. K., Španinger, E., Košir, I. J., Knez, Ž., & Bren, U. (2019) · Nutrients · doi:10.3390/nu11020257 · Cited by 205 · see citing works

Therapeutic Versatility of Resveratrol Derivatives

Nawaz, W., Zhou, Z.-Q., Deng, S., Ma, X., Ma, X., Li, C., & Shu, X. H. (2017) · Nutrients · doi:10.3390/nu9111188 · Cited by 175 · see citing works

Resveratrol: Twenty Years of Growth, Development and Controversy

Pezzuto, J. M. (2018) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2018.176 · Cited by 164 · see citing works

Lipid-Based Nanoparticles in Delivering Bioactive Compounds for Improving Therapeutic Efficacy

Patel, P., Garala, K., Singh, S. K., Prajapati, B. G., & Chittasupho, C. (2024) · Pharmaceuticals · doi:10.3390/ph17030329 · Cited by 151 · see citing works

The polyphenols resveratrol and epigallocatechin-3-gallate restore the severe impairment of mitochondria in hippocampal progenitor cells from a Down syndrome mouse model

Valenti, D., Lidia de, B. A. R. I., Rasmo, D. D., Signorile, A., Henrion‐Caude, A., Contestabile, A., & Vacca, R. A. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2016.03.003 · Cited by 128 · see citing works

Molecular and Cellular Mechanisms of Propolis and Its Polyphenolic Compounds against Cancer

Oršolić, N., & Jembrek, M. J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231810479 · Cited by 132 · see citing works

Resveratrol Protects against Sepsis-Associated Encephalopathy and Inhibits the NLRP3/IL-1<i>β</i>Axis in Microglia

Sui, D.-M., Xie, Q., Yi, W.-J., Gupta, S., Yu, X.-Y., Li, J.-B., Wang, J., Wang, J.-F., & Deng, X.-M. (2016) · Mediators of Inflammation · doi:10.1155/2016/1045657 · Cited by 124 · see citing works

New phytochemicals as potential human anti-aging compounds: Reality, promise, and challenges

Corrêa, R. C. G., Peralta, R. M., Haminiuk, C. W. I., Maciel, G. M., Bracht, A., & Ferreira, I. C. F. R. (2016) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2016.1233860 · Cited by 123 · see citing works

Nutritional prevention of cognitive decline and dementia.

Dominguez, L. J., & Barbagallo, M. (2018) · Acta bio-medica dell'Ateneo parmense/Acta biomedica · doi:10.23750/abm.v89i2.7401 · Cited by 123 · see citing works

Paeoniflorin, a Natural Product With Multiple Targets in Liver Diseases—A Mini Review

Ma, X., Zhang, W., Jiang, Y., Wen, J., Wei, S., & Zhao, Y. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00531 · Cited by 114 · see citing works

Evidence for the free radical/oxidative stress theory of ageing from the CHANCES consortium: a meta-analysis of individual participant data

Schöttker, B., Brenner, H., Jansen, E. H. J. M., Gardiner, J., Peasey, A., Kubínová, R., Pająk, A., Topór-Mądry, R., Tamošiūnas, A., Saum, K.-U., et al. (2015) · BMC Medicine · doi:10.1186/s12916-015-0537-7 · Cited by 107 · see citing works

Natural Products from Chinese Medicines with Potential Benefits to Bone Health

Che, C., Wong, M., & Lam, C. W. K. (2016) · Molecules · doi:10.3390/molecules21030239 · Cited by 106 · see citing works

Upregulation of PD‑L1 expression by resveratrol and piceatannol in breast and colorectal cancer cells occurs via HDAC3/p300‑mediated NF‑κB signaling

Lucas, J., Hsieh, T., Halicka, H. D., Darżynkiewicz, Z., & WU, J. M. (2018) · International Journal of Oncology · doi:10.3892/ijo.2018.4512 · Cited by 106 · see citing works

Health Benefits of Resveratrol in Kidney Disease: Evidence from In Vitro and In Vivo Studies

Hartogh, D. J. D., & Tsiani, E. (2019) · Nutrients · doi:10.3390/nu11071624 · Cited by 106 · see citing works

Antidiabetic Properties of Curcumin II: Evidence from In Vivo Studies

Hartogh, D. J. D., Gabriel, A., & Tsiani, E. (2019) · Nutrients · doi:10.3390/nu12010058 · Cited by 100 · see citing works

Resveratrol inhibits Hexokinases II mediated glycolysis in non-small cell lung cancer via targeting Akt signaling pathway

Li, W., Ma, X., Li, N., Liu, H., Dong, Q., Zhang, J., Yang, C., Liu, Y., Liang, Q., Zhang, S., et al. (2016) · Experimental Cell Research · doi:10.1016/j.yexcr.2016.11.002 · Cited by 98 · see citing works

Antidiabetic Properties of Curcumin I: Evidence from In Vitro Studies

Hartogh, D. J. D., Gabriel, A., & Tsiani, E. (2020) · Nutrients · doi:10.3390/nu12010118 · Cited by 96 · see citing works

Resveratrol Plays a Protective Role against Premature Ovarian Failure and Prompts Female Germline Stem Cell Survival

Jiang, Y., Zhang, Z., Cha, L., Li, L., Zhu, D., Fang, Z., He, Z., Huang, J., & Pan, Z. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20143605 · Cited by 90 · see citing works

Beer Polyphenols—Bitterness, Astringency, and Off-Flavors

Habschied, K. J., Košir, I. J., Krstanović, V., Kumrić, G., & Mastanjević, K. M. (2021) · Beverages · doi:10.3390/beverages7020038 · Cited by 87 · see citing works

The Epigenetic Link between Polyphenols, Aging and Age-Related Diseases

Arora, I., Sharma, M., Sun, L.-O. Y., & Tollefsbol, T. (2020) · Genes · doi:10.3390/genes11091094 · Cited by 72 · see citing works

Creating a Water‐Soluble Resveratrol‐Based Antioxidant by Site‐Selective Enzymatic Glucosylation

Lepak, A. J., Gutmann, A., Kulmer, S. T., & Nidetzky, B. (2015) · ChemBioChem · doi:10.1002/cbic.201500284 · Cited by 85 · see citing works

Resveratrol ameliorates chronic unpredictable mild stress-induced depression-like behavior: involvement of the HPA axis, inflammatory markers, BDNF, and Wnt/&amp;beta;-catenin pathway in rats

Yang, X.-H., Song, S.-Q., & Xu, Y. (2017) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s150028 · Cited by 84 · see citing works

Polyphenols and Their Potential Role in Preventing Skeletal Muscle Atrophy

Salucci, S., & Falcieri, E. (2020) · Nutrition Research · doi:10.1016/j.nutres.2019.11.004 · Cited by 83 · see citing works

Blood Pressure–Lowering by the Antioxidant Resveratrol Is Counterintuitively Mediated by Oxidation of cGMP-Dependent Protein Kinase

Prysyazhna, O. D., Wolhuter, K., Switzer, C., Santos, C. X. C., Yang, X., Lynham, S., Shah, A. M., Eaton, P., & Burgoyne, J. R. (2019) · Circulation · doi:10.1161/circulationaha.118.037398 · Cited by 81 · see citing works

Modulation of Aromatase by Phytoestrogens

Lephart, E. D. (2015) · Enzyme Research · doi:10.1155/2015/594656 · Cited by 86 · see citing works

Resveratrol Reverses Functional Chagas Heart Disease in Mice

Vilar-Pereira, G., Carneiro, V. C., dos Santos, H. A. M., Vicentino, A. R. R., Ramos, I. P., Giarola, N. L. L., Feijó, D. F., Meyer‐Fernandes, J. R., Paula-Neto, H. A., Medei, E. H., et al. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005947 · Cited by 81 · see citing works

Natural Stilbenoids Have Anti-Inflammatory Properties in Vivo and Down-Regulate the Production of Inflammatory Mediators NO, IL6, and MCP1 Possibly in a PI3K/Akt-Dependent Manner

Eräsalo, H., Hämäläinen, M., Leppänen, T., Mäki‐Opas, I., Laavola, M., Haavikko, R., Yli‐Kauhaluoma, J. T., & Moilanen, E. (2018) · Journal of Natural Products · doi:10.1021/acs.jnatprod.7b00384 · Cited by 77 · see citing works

Molecular Mechanisms of Oxidative Stress in Acute Kidney Injury: Targeting the Loci by Resveratrol

Rashid, H., Jali, A. M., Akhter, M. S., & Abdi, S. A. H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms25010003 · Cited by 77 · see citing works

Caloric restriction and exercise “mimetics”: ready for prime time

Handschin, C. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2015.11.009 · Cited by 72 · see citing works

At the interface of antioxidant signalling and cellular function: Key polyphenol effects

Kerimi, A., & Williamson, G. (2016) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201500940 · Cited by 71 · see citing works

Pharmaceutical perspective on the translational hurdles of phytoconstituents and strategies to overcome

Sayed, N., Khurana, A., & Godugu, C. (2019) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2019.101201 · Cited by 71 · see citing works

High-speed countercurrent chromatography as an efficient technique for large separation of plant polyphenols: A review

Li, L., Zhao, J., Yang, T., & Sun, B. (2022) · Food Research International · doi:10.1016/j.foodres.2022.110956 · Cited by 71 · see citing works

Effect of Resveratrol on Markers of Oxidative Stress and Sirtuin 1 in Elderly Adults with Type 2 Diabetes

García-Martínez, B. I., Ruíz-Ramos, M., Pedraza‐Chaverrí, J., Santiago‐Osorio, E., & Mendoza-Núñez, V. M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087422 · Cited by 73 · see citing works

Brain targeting of resveratrol through intranasal lipid vesicles labelled with gold nanoparticles: in vivo evaluation and bioaccumulation investigation using computed tomography and histopathological examination

Salem, H. F., Kharshoum, R. M., Abou‐Taleb, H. A., & Naguib, D. M. (2019) · Journal of drug targeting · doi:10.1080/1061186x.2019.1608553 · Cited by 68 · see citing works

Effects of Supplementation with Natural Antioxidants on Oocytes and Preimplantation Embryos

Budani, M. C., & Tiboni, G. M. (2020) · Antioxidants · doi:10.3390/antiox9070612 · Cited by 68 · see citing works

Polyphenol-Conjugated Bimetallic Au@AgNPs for Improved Wound Healing

Orłowski, P., Żmigrodzka, M., Tomaszewska, E., Ranoszek‐Soliwoda, K., Pająk, B., Słońska, A., Cymerys, J., Celichowski, G., Grobelny, J., & Krzyżowska, M. (2020) · International Journal of Nanomedicine · doi:10.2147/ijn.s252027 · Cited by 70 · see citing works

Resveratrol has anti-thyroid effects both in vitro and in vivo

Giuliani, C., Iezzi, M., Ciolli, L., Hysi, A., Bucci, I., Santo, S. D., Rossi, C., Zucchelli, M., & Napolitano, G. (2017) · Food and Chemical Toxicology · doi:10.1016/j.fct.2017.06.044 · Cited by 66 · see citing works

The red wine component ellagic acid induces autophagy and exhibits anti‐lung cancer activity in vitro and in vivo

Duan, J., Zhan, J., Wang, G., Zhao, X., Huang, W., & Zhou, G. (2018) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13899 · Cited by 65 · see citing works

Dysregulation of the Hippo pathway signaling in aging and cancer

Yeung, Y. T., Guerrero‐Castilla, A., Cano, M., Muñoz, M. F., Ayala, A., & Argüelles, S. (2019) · Pharmacological Research · doi:10.1016/j.phrs.2019.03.018 · Cited by 62 · see citing works

Role of resveratrol in the management of insulin resistance and related conditions: Mechanism of action

Oshaghi, E. A., Goodarzi, M. T., Higgins, V., & Adeli, K. (2017) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408363.2017.1343274 · Cited by 62 · see citing works

Epigenetic regulation of active Chinese herbal components for cancer prevention and treatment: A follow-up review

Huang, Z., Huang, Q., Ji, L., Wang, Y., Qi, X., Liu, L., Liu, Z., & Lu, L. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.09.023 · Cited by 62 · see citing works

The estrogenic activity of resveratrol: a comprehensive review ofin vitroandin vivoevidence and the potential for endocrine disruption

Qasem, R. J. (2020) · Critical Reviews in Toxicology · doi:10.1080/10408444.2020.1762538 · Cited by 64 · see citing works

Resveratrol regulates gene transcription via activation of stimulus-responsive transcription factors

Thiel, G., & Rößler, O. G. (2016) · Pharmacological Research · doi:10.1016/j.phrs.2016.12.029 · Cited by 60 · see citing works

Multi-target natural products as alternatives against oxidative stress in Chronic Obstructive Pulmonary Disease (COPD)

Gonçalves, P. B., & Romeiro, N. C. (2018) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2018.12.020 · Cited by 60 · see citing works

Poly herbal formulation with anti-elastase and anti-oxidant properties for skin anti-aging

Sundaram, I. K., Sarangi, D. D., Sundararajan, V., George, S., & Mohideen, S. S. (2018) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-018-2097-9 · Cited by 61 · see citing works

Recent Developments in Nanoparticle Formulations for Resveratrol Encapsulation as an Anticancer Agent

Ali, M. U., Benfante, V., Raimondo, D. D., Salvaggio, G., Tuttolomondo, A., & Comelli, A. (2024) · Pharmaceuticals · doi:10.3390/ph17010126 · Cited by 58 · see citing works

Resveratrol lowers synovial hyperplasia, inflammatory markers and oxidative damage in an acute antigen-induced arthritis model

Riveiro-Naveira, R. R., Valcarcel‐Ares, M. N., Becerril, M. A., Vaamonde‐García, C., Loureiro, J., Hermida-Carballo, L., López-Peláez, E., Blanco, F. J., & López-Armada, M. J. (2016) · Lara D. Veeken · doi:10.1093/rheumatology/kew255 · Cited by 58 · see citing works

Resveratrol as Chemosensitizer Agent: State of Art and Future Perspectives

Cocetta, V., Quagliariello, V., Fiorica, F., Berretta, M., & Montopoli, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22042049 · Cited by 56 · see citing works

Effects of resveratrol and genistein on nuclear factor-κB, tumor necrosis factor-α and matrix metalloproteinase-9 in patients with chronic obstructive pulmonary disease

LIU, X.-J., Bao, H., ZENG, X.-L., & WEI, J.-M. (2016) · Molecular Medicine Reports · doi:10.3892/mmr.2016.5057 · Cited by 56 · see citing works

Therapeutic Effects of Traditional Chinese Medicine on Spinal Cord Injury: A Promising Supplementary Treatment in Future

Zhang, Q., Yang, H., An, J., Zhang, R., Chen, B., & Hao, D. (2016) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2016/8958721 · Cited by 56 · see citing works

Downregulation of proinflammatory cytokines in HTLV-1-infected T cells by Resveratrol

Fuggetta, M. P., Bordignon, V., Cottarelli, A., Macchi, B., Frezza, C., Cordiali‐Fei, P., Ensoli, F., Ciafrè, S., Marino‐Merlo, F., Mastino, A., et al. (2016) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-016-0398-8 · Cited by 53 · see citing works

Resveratrol protects HaCaT cells from ultraviolet B-induced photoaging via upregulation of HSP27 and modulation of mitochondrial caspase-dependent apoptotic pathway

Zhou, F., Huang, X., Pan, Y., Cao, D., Liu, C., Liu, Y., & Chen, A. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.03.207 · Cited by 52 · see citing works

Relationship of Wine Consumption with Alzheimer’s Disease

Reale, M., Costantini, E., Jagarlapoodi, S., Khan, H. Z., Belwal, T., & Cichelli, A. (2020) · Nutrients · doi:10.3390/nu12010206 · Cited by 53 · see citing works

Resveratrol Bioavailability After Oral Administration: A Meta‐Analysis of Clinical Trial Data

Szymkowiak, I., Marcinkowska, J., Kucińska, M., Regulski, M., & Murias, M. (2024) · Phytotherapy Research · doi:10.1002/ptr.8379 · Cited by 54 · see citing works

Targeting cancer stem cells with dietary phytochemical - Repositioned drug combinations

Chan, M. M.-Y., Chen, R., & Fong, D. (2018) · Cancer Letters · doi:10.1016/j.canlet.2018.06.034 · Cited by 52 · see citing works

Molecular mechanisms of resveratrol as chemo and radiosensitizer in cancer

Cotino‐Nájera, S., Herrera, L. A., Domínguez-Gómez, G., & Díaz‐Chávez, J. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1287505 · Cited by 52 · see citing works

Creating Space for Large Acceptors: Rational Biocatalyst Design for Resveratrol Glycosylation in an Aqueous System

Dirks‐Hofmeister, M. E., Verhaeghe, T., Winter, K. D., & Desmet, T. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201503605 · Cited by 51 · see citing works

A Brief Review on Resveratrol

Malviya, V., Tawar, M. G., Burange, P. J., & Jodh, R. V. (2022) · Asian Journal of Research in Pharmaceutical Sciences · doi:10.52711/2231-5659.2022.00027 · Cited by 50 · see citing works

Resveratrol and Its Derivatives in Inflammatory Skin Disorders—Atopic Dermatitis and Psoriasis: A Review

Marko, M., & Pawliczak, R. (2023) · Antioxidants · doi:10.3390/antiox12111954 · Cited by 50 · see citing works

Effect of Resveratrol on the Prevention of Intra-Abdominal Adhesion Formation in a Rat Model

Wei, G., Chen, X., Wang, G., Fan, L., Wang, K., & Li, X. (2016) · Cellular Physiology and Biochemistry · doi:10.1159/000445603 · Cited by 49 · see citing works

Progress in the Treatment of Central Nervous System Diseases Based on Nanosized Traditional Chinese Medicine

Li, J., Long, Q., Ding, H., Wang, Y., Luo, D., Li, Z., & Zhang, W. (2024) · Advanced Science · doi:10.1002/advs.202308677 · Cited by 47 · see citing works

Resveratrol Inhibits Periodontitis‐Related Bone Loss in Rats Subjected to Cigarette Smoke Inhalation

Ribeiro, F. V., Pino, D. S., Franck, F. C., Benatti, B. B., Tenenbaum, H. C., Davies, J. E., Pimentel, S. P., Casarin, R. C. V., Cirano, F. R., & Casati, M. Z. (2017) · Journal of Periodontology · doi:10.1902/jop.2017.170025 · Cited by 48 · see citing works

Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL TM)

Kemper, C., Behnam, D., Brothers, S. P., Wahlestedt, C., Volmar, C., Bennett, D., & Hayward, M. A. (2022) · AAPS Open · doi:10.1186/s41120-022-00058-1 · Cited by 47 · see citing works

Beneficial effects of white wine polyphenols-enriched diet on Alzheimer’s disease-like pathology

Mendes, D., Oliveira, M. M., Moreira, P. I., Coutinho, J., Nunes, F. M., Pereira, D. M., Valentão, P., Andrade, P. B., & Videira, R. A. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.02.001 · Cited by 45 · see citing works

Complementary and Alternative Therapies in Amyotrophic Lateral Sclerosis

Bedlack, R., Joyce, N. C., Carter, G. T., Paganoni, S., & Karam, C. (2015) · Neurologic Clinics · doi:10.1016/j.ncl.2015.07.008 · Cited by 45 · see citing works

Health-beneficial nutraceuticals—myth or reality?

Sauer, S., & Plauth, A. (2017) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-8068-5 · Cited by 44 · see citing works

Using Next-Generation Sequencing Technology to Explore Genetic Pathways in Endophytic Fungi in the Syntheses of Plant Bioactive Metabolites

Bielecka, M., Pencakowski, B., & Nicoletti, R. (2022) · Agriculture · doi:10.3390/agriculture12020187 · Cited by 42 · see citing works

An Overview of Crucial Dietary Substances and Their Modes of Action for Prevention of Neurodegenerative Diseases

Pogačnik, L., Ota, A., & Ulrih, N. P. (2020) · Cells · doi:10.3390/cells9030576 · Cited by 43 · see citing works

Epigenetic regulation by polyphenols in diabetes and related complications

Ullah, H., Filippis, A. D., Santarcangelo, C., & Daglia, M. (2020) · Mediterranean Journal of Nutrition and Metabolism · doi:10.3233/mnm-200489 · Cited by 42 · see citing works

Equol’s Anti-Aging Effects Protect against Environmental Assaults by Increasing Skin Antioxidant Defense and ECM Proteins While Decreasing Oxidative Stress and Inflammation

Lephart, E. (2018) · Cosmetics · doi:10.3390/cosmetics5010016 · Cited by 42 · see citing works

Identification of resveratrol analogs as potent anti‐dengue agents using a cell‐based assay

Han, Y., Penthala, N. R., Oliveira, M., Mésplède, T., Xu, H., Quan, Y., Crooks, P. A., & Wainberg, M. A. (2016) · Journal of Medical Virology · doi:10.1002/jmv.24660 · Cited by 41 · see citing works

Effect of Resveratrol on Pregnancy, Prenatal Complications and Pregnancy-Associated Structure Alterations

Ramli, I., Posadino, A. M., Giordo, R., Fenu, G., Fardoun, M., Iratni, R., Eid, A. H., Zayed, H., & Pintus, G. (2023) · Antioxidants · doi:10.3390/antiox12020341 · Cited by 39 · see citing works

Upregulation of FcγRIIB by resveratrol via NF-κB activation reduces B-cell numbers and ameliorates lupus

Jhou, J., Chen, S.-J., Huang, H., Lin, W., Huang, D.-Y., & Tzeng, S. (2017) · Experimental & Molecular Medicine · doi:10.1038/emm.2017.144 · Cited by 40 · see citing works

Incorporating Natural Products, Pharmaceutical Drugs, Self-Care and Digital/Mobile Health Technologies into Molecular-Behavioral Combination Therapies for Chronic Diseases

Bulaj, G. W., Ahern, M., Kuhn, A. K., Judkins, Z., Bowen, R. C., & Chen, Y. (2016) · Current Clinical Pharmacology · doi:10.2174/1574884711666160603012237 · Cited by 40 · see citing works

Leveraging the Cardio-Protective and Anticancer Properties of Resveratrol in Cardio-Oncology

Abdelgawad, I. Y., Grant, M. K. O., & Zordoky, B. N. M. (2019) · Nutrients · doi:10.3390/nu11030627 · Cited by 39 · see citing works

Nuclear Peroxisome Proliferator-Activated Receptors (PPARs) as Therapeutic Targets of Resveratrol for Autism Spectrum Disorder

Barone, R. M. E., Rizzo, R., Tabbı̀, G., Malaguarnera, M., Frye, R. E., & Bastin, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20081878 · Cited by 39 · see citing works

Development of a Solid Dispersion System for Improving the Oral Bioavailability of Resveratrol in Rats

Chang, C., Wong, C.-Y., Wu, Y., & Hsu, M. (2016) · European Journal of Drug Metabolism and Pharmacokinetics · doi:10.1007/s13318-016-0339-0 · Cited by 38 · see citing works

New natural amino acid-bearing prodrugs boost pterostilbene’s oral pharmacokinetic and distribution profile

Azzolini, M., Mattarei, A., Spina, M. L., Fanin, M., Chiodarelli, G., Romio, M., Zoratti, M., Paradisi, C., & Biasutto, L. (2017) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2017.02.017 · Cited by 38 · see citing works

Resveratrol protects neuronal cells from isoflurane‑induced inflammation and oxidative stress‑associated death by attenuating apoptosis via Akt/p38 MAPK signaling

Hu, W., Yang, E., Ye, J., Han, W., & Du, Z. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.5527 · Cited by 36 · see citing works

Resveratrol Prevents Right Ventricle Remodeling and Dysfunction in Monocrotaline-Induced Pulmonary Arterial Hypertension with a Limited Improvement in the Lung Vasculature

Vázquez‐Garza, E., Bernal‐Ramírez, J., Carlos Jerjes-Sánchez, D., Lozano, O., Acuna-Morin, E. E., Tamez, M. V., Ramos-González, M. R., Chapoy‐Villanueva, H., Pérez-Plata, L., Sánchez-Trujillo, L., et al. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/1841527 · Cited by 36 · see citing works

Phytochemicals and cancer chemoprevention

Dave, A., Parande, F., Park, E., & Pezzuto, J. M. (2020) · Journal of Cancer Metastasis and Treatment · doi:10.20517/2394-4722.2020.106 · Cited by 36 · see citing works

Resveratrol counters systemic lupus erythematosus-associated atherogenicity by normalizing cholesterol efflux

Voloshyna, I., Teboul, I., Littlefield, M. J., Siegart, N. M., Turi, G. K., Fazzari, M. J., Carsons, S. E., DeLeon, J. R., & Reiss, A. B. (2016) · Experimental Biology and Medicine · doi:10.1177/1535370216647181 · Cited by 36 · see citing works

The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea

García-Alcántara, F., Murillo‐Cuesta, S., Pulido, S., Bermúdez‐Muñoz, J. M., Martínez‐Vega, R., Milo, M., Varela‐Nieto, I., & Rivera, T. (2017) · Hearing Research · doi:10.1016/j.heares.2017.12.004 · Cited by 36 · see citing works

Resveratrol-mediated glycemic regulation is blunted by curcumin and is associated to modulation of gut microbiota

Sreng, N., Champion, S., Martin, J., Khelaifia, S., Christensen, J. E., Padmanabhan, R., Azalbert, V., Blasco‐Baqué, V., Loubières, P., Pechère, L., et al. (2019) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2019.108218 · Cited by 34 · see citing works

Resveratrol supplementation: Where are we now and where should we go?

Novelle, M. G., Wahl, D., Diéguez, C., Bernier, M., & de Cabo, R. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2015.01.002 · Cited by 247 · see citing works

Significance of Resveratrol in Clinical Management of Chronic Diseases

Wahab, A., Gao, K., Jia, C., Zhang, F., Tian, G., Murtaza, G., & Chen, J. (2017) · Molecules · doi:10.3390/molecules22081329 · Cited by 108 · see citing works

Resveratrol and health—A comprehensive review of human clinical trials

Smoliga, J. M., Baur, J. A., & Hausenblas, H. A. (2011) · Molecular Nutrition &amp; Food Research · doi:10.1002/mnfr.201100143 · Cited by 594 · see citing works

Pharmacological Aspects of Resveratrol

Bandyopadhyay, D. (2019) · Biomedical Journal of Scientific & Technical Research · doi:10.26717/bjstr.2019.16.002815

Resveratrol in mammals: effects on aging biomarkers, age‐related diseases, and life span

Marchal, J., Pifferi, F., & Aujard, F. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12214 · Cited by 99 · see citing works