On Cue: Striatal Ups and Downs in Addictions
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Gambling-related cues take on increased incentive salience, while other non-related or unfamiliar cues may become less important or even inhibit motivation.
“This finding implies that while gambling-related cues take on increased incentive salience, other non-related or unfamiliar cues may become less important or even inhibit motivation (Leyton, 2007; 2014; Leyton & Vezina, 2012; 2014).”
From Cued for Risk: Evidence for an Incentive Sensitization Framework to Explain the Interplay between Stress and Anxiety, Substance Abuse, and Reward Uncertainty in Disordered Gambling Behavior (2019) · cites this paper as Leyton & Vezina, 2012
Contradictory reports of striatal dopamine response can be explained by the absence of familiar or relevant gambling cues during laboratory testing.
“However, it has been suggested that such contradictory reports can be explained by the absence of familiar or relevant gambling cues during laboratory testing (Leyton & Vezina, 2012)”
From Cued for Risk: Evidence for an Incentive Sensitization Framework to Explain the Interplay between Stress and Anxiety, Substance Abuse, and Reward Uncertainty in Disordered Gambling Behavior (2019) · cites this paper as Leyton & Vezina, 2012
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“This finding implies that while gambling-related cues take on increased incentive salience, other non-related or unfamiliar cues may become less important or even inhibit motivation (Leyton, 2007, 2014; Leyton & Vezina, 2012, 2014).”
- Authors
- Leyton, M., & Vezina, P.
- Affiliations
- McGill University (CA)
- University of Chicago (US)
- Corresponding author
- Leyton, Marco
- ORCID
- Leyton, Marco
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2012-11
- Volume
- 72
- Issue
- 10
- Pages
- e21-e22
- ISSN
- 0006-3223 (ISSN-L)
- PMC
- PMC3979432
- OpenAlex
- W2049538199
- Cited by
- 53
- References
- 39
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 2 · 2018: 2 · 2017: 3 · 2016: 3 · 2015: 7 · 2014: 14 · 2013: 6 · 2012: 1
- FWCI
- 10.18
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Drug Abuse (R01DA009397)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- problem gambling, striatum, reward cues, cue reactivity, gambling addiction, monetary rewards, cue type
- MeSH terms
- Cues, Dopamine, Evoked Potentials, Visual, Gambling, Humans, Magnetic Resonance Imaging, Photic Stimulation, Reward, Behavior, Addictive, Neostriatum, Positron-Emission Tomography
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