Wntless, a Conserved Membrane Protein Dedicated to the Secretion of Wnt Proteins from Signaling Cells

The Wnt Signaling Pathway in Development and Disease

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Mutations affecting segment number and polarity in Drosophila

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Wnt signalling in stem cells and cancer

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Wnt proteins are lipid-modified and can act as stem cell growth factors

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MECHANISMS OF WNT SIGNALING IN DEVELOPMENT

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A new member of the frizzled family from Drosophila functions as a Wingless receptor

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Zebrafish Prickle, a Modulator of Noncanonical Wnt/Fz Signaling, Regulates Gastrulation Movements

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Wnt genes

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Direct and Long-Range Action of a Wingless Morphogen Gradient

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Lipoprotein particles are required for Hedgehog and Wingless signalling

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Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos

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Secretion of Wnt Ligands Requires Evi, a Conserved Transmembrane Protein

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Dispatched, a Novel Sterol-Sensing Domain Protein Dedicated to the Release of Cholesterol-Modified Hedgehog from Signaling Cells

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Wnt/Wingless Signaling Requires BCL9/Legless-Mediated Recruitment of Pygopus to the Nuclear β-Catenin-TCF Complex

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Wnt Signaling Polarizes an Early C. elegans Blastomere to Distinguish Endoderm from Mesoderm

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Senseless, a Zn Finger Transcription Factor, Is Necessary and Sufficient for Sensory Organ Development in Drosophila

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A superfamily of membrane-bound O -acyltransferases with implications for Wnt signaling

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pangolinencodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila

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Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling

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Wingless gradient formation in the Drosophila wing

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Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing

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Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development.

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Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis

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Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless

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The wingless signalling pathway and the patterning of the wing margin in Drosophila

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The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing.Preprint

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Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface

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The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation

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Mesd Encodes an LRP5/6 Chaperone Essential for Specification of Mouse Embryonic Polarity

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The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously

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Drosophila Segment Polarity Gene Product Porcupine Stimulates the Posttranslational N-Glycosylation of Wingless in the Endoplasmic Reticulum

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Neuronal cell migration in C. elegans : regulation of Hox gene expression and cell position

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Roles for 147 embryonic lethal genes on C.elegans chromosome I identified by RNA interference and video microscopy

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Glypicans shunt the Wingless signal between local signalling and further transport

Franch‐Marro, X., Marchand, O., Piddini, E., Ricardo, S. A. V., Alexandre, C., & Vincent, J. (2005) · Development · doi:10.1242/dev.01639 · Cited by 149 · see citing works

DWnt4 Regulates Cell Movement and Focal Adhesion Kinase during Drosophila Ovarian Morphogenesis

Cohen, E. D., Mariol, M., Wallace, R. M. H., Weyers, J., Kamberov, Y. G., Pradel, J., & Wilder, E. L. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00142-9 · Cited by 142 · see citing works

Boca, an Endoplasmic Reticulum Protein Required for Wingless Signaling and Trafficking of LDL Receptor Family Members in Drosophila

Culí, J., & Mann, R. S. (2003) · Cell · doi:10.1016/s0092-8674(02)01279-5 · Cited by 138 · see citing works

Canonical and non‐canonical Wnt signaling pathways in Caenorhabditis elegans : variations on a common signaling theme

Korswagen, H. C. (2002) · BioEssays · doi:10.1002/bies.10145 · Cited by 133 · see citing works

Protruding Vulva Mutants Identify Novel Loci and Wnt Signaling Factors That Function During Caenorhabditis elegans Vulva Development

Eisenmann, D. M., & Kim, S. K. (2000) · Genetics · doi:10.1093/genetics/156.3.1097 · Cited by 119 · see citing works

DWnt-2, a Drosophila Wnt gene required for the development of the male reproductive tract, specifies a sexually dimorphic cell fatePreprint

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Producing Cells Retain and Recycle Wingless in Drosophila Embryos

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Wnt signalling in Caenorhabditis elegans : regulating repressors and polarizing the cytoskeleton

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A screen for genes expressed in Drosophila imaginal discs

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Socket Cells Mediate Spicule Morphogenesis in Caenorhabditis elegans Males

Jiang, L. I., & Sternberg, P. W. (1999) · Developmental Biology · doi:10.1006/dbio.1999.9293 · Cited by 23 · see citing works

Cell Signaling: Wingless and Glypicans Together Again

Blair, S. S. (2005) · Current Biology · doi:10.1016/j.cub.2005.01.026 · Cited by 14 · see citing works

Wnt/β-catenin signaling and disease

Clevers, H., & Nusse, R. (2012) · Cell · doi:10.1016/j.cell.2012.05.012 · Cited by 5,554 · see citing works

Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities

Nusse, R., & Clevers, H. (2017) · Cell · doi:10.1016/j.cell.2017.05.016 · Cited by 4,342 · see citing works

Wnt signaling in cancer

Zhan, T., Rindtorff, N., & Boutros, M. (2017) · Oncogene · doi:10.1038/onc.2016.304 · Cited by 2,626 · see citing works

Wnt signal transduction pathways

Komiya, Y., & Habas, R. (2008) · Organogenesis · doi:10.4161/org.4.2.5851 · Cited by 1,528 · see citing works

Wnt Signaling: Multiple Pathways, Multiple Receptors, and Multiple Transcription Factors

Gordon, M. D., & Nusse, R. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.r600015200 · Cited by 1,333 · see citing works

Optimized CRISPR/Cas tools for efficient germline and somatic genome engineering in <i>Drosophila</i>

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Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver

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Secretion of Wnt Ligands Requires Evi, a Conserved Transmembrane Protein

Bartscherer, K., Pelte, N., Ingelfinger, D., & Boutros, M. (2006) · Cell · doi:10.1016/j.cell.2006.04.009 · Cited by 580 · see citing works

Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation

Chen, D., Jarrell, A., Guo, C., Lang, R., & Atit, R. (2012) · Development · doi:10.1242/dev.076463 · Cited by 260 · see citing works

The Wnt code: cnidarians signal the way

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Helping Wingless take flight: how WNT proteins are secreted

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Antagonistic self-organizing patterning systems control maintenance and regeneration of the anteroposterior axis in planarians

Stückemann, T., Cleland, J. P., Werner, S., Thi-Kim Vu, H., Bayersdorf, R., Liu, S.-Y., Friedrich, B., Jülicher, F., & Rink, J. C. (2017) · Developmental Cell · doi:10.1016/j.devcel.2016.12.024 · Cited by 133 · see citing works

WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis

Kaiser, K., Gyllborg, D., Procházka, J., Salašová, A., Kompaníková, P., Molina, F. L., Laguna-Goya, R., Radaszkiewicz, T., Harnoš, J., Procházková, M., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-09298-4 · Cited by 87 · see citing works

Epithelial WNT ligands are essential drivers of intestinal stem cell activation

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Neuron activity–induced Wnt signaling up-regulates expression of brain-derived neurotrophic factor in the pain neural circuit

Zhang, W., Shi, Y., Peng, Y., Zhong, L., Zhu, S., Zhang, W., & Tang, S.-J. (2018) · Journal of Biological Chemistry · doi:10.1074/jbc.ra118.002840 · Cited by 59 · see citing works

The Function of Wnt Ligands on Osteocyte and Bone Remodeling

Du, J. H., Lin, S. X., Wu, X. L., Yang, S. M., Cao, L. Y., Zheng, A., Wu, J. N., & Jiang, X. Q. (2019) · Journal of Dental Research · doi:10.1177/0022034519854704 · Cited by 35 · see citing works

Faculty Opinions recommendation of Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

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Insights into the Wnt Signaling Pathway Evolution

Rismani, E., Haghighi-Najafabadi, N., Far, B. E., Shahbazi, B., & Mafakher, L. (2022) · Physiology · doi:10.5772/intechopen.108012 · Cited by 4 · see citing works

Wnt family members regulating osteogenesis and their origins

Kobayashi, Y., Iwamoto, R., He, Z., & Udagawa, N. (2024) · Journal of Bone and Mineral Metabolism · doi:10.1007/s00774-024-01554-y · Cited by 14 · see citing works

Expression Pattern of Wnt Signaling Components in the Adult Intestine

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A model for signaling specificity of Wnt/Frizzled combinations through co‐receptor recruitment

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