Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries

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Single-cell chromatin accessibility reveals principles of regulatory variation

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Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

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Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

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Single-Cell RNA-Seq Reveals Dynamic, Random Monoallelic Gene Expression in Mammalian Cells

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Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses

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A Multiplexed Single-Cell CRISPR Screening Platform Enables Systematic Dissection of the Unfolded Protein Response

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Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

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Quantitative single-cell RNA-seq with unique molecular identifiers

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Microglia development follows a stepwise program to regulate brain homeostasis

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Single-cell spatial reconstruction reveals global division of labour in the mammalian liver

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Pathogen Cell-to-Cell Variability Drives Heterogeneity in Host Immune Responses

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Monocyte Single-Cell Multimodal Profiling in Cardiovascular Disease Risk States

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Digital PCR for Single-Cell Analysis

Fang, W., Liu, X., Maiga, M., Cao, W., Mu, Y., Yan, Q., & Zhu, Q. (2024) · Biosensors · doi:10.3390/bios14020064 · Cited by 22 · see citing works

Cancer research in the era of immunogenomics

Wolf, Y., & Samuels, Y. (2018) · ESMO Open · doi:10.1136/esmoopen-2018-000475 · Cited by 20 · see citing works

Expression of Urea Transporter B in Normal and Injured Brain

Huang, B., Wang, H., Zhong, D., Meng, J., Li, M., Yang, B., & Ran, J. (2021) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2021.591726 · Cited by 19 · see citing works

Single-cell sequencing in hematology

Brierley, C. K., & Mead, A. J. (2019) · Current Opinion in Oncology · doi:10.1097/cco.0000000000000613 · Cited by 19 · see citing works

Leukemic stem cell signatures in Acute myeloid leukemia- targeting the Guardians with novel approaches

Thakral, D., Gupta, R., & Khan, A. (2022) · Stem Cell Reviews and Reports · doi:10.1007/s12015-022-10349-5 · Cited by 17 · see citing works

Lessons From Transcriptome Analysis of Autoimmune Diseases

Nagafuchi, Y., Yanaoka, H., & Fujio, K. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.857269 · Cited by 18 · see citing works

Prognostic and Immunological Value of Angiotensin-Converting Enzyme 2 in Pan-Cancer

Feng, H., Wei, X., Pang, L., Wu, Y., Hu, B., Ruan, Y., Liu, Z., Liu, J., & Wang, T. (2020) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.00189 · Cited by 18 · see citing works

Exploring mechanisms of Chaihu-Shugan-San against liver fibrosis by integrated multi-omics and network pharmacology approach

Xie, Z., Xie, Z., Pineda-Trujillo, N., Yang, T., & Yang, C. (2022) · Bioscience Reports · doi:10.1042/bsr20221030 · Cited by 17 · see citing works

Single-Cell RNA-Sequencing in Astrocyte Development, Heterogeneity, and Disease

Gao, M.-Y., Wang, J., He, J. M., Gao, R., Zhang, Y., & Li, X. (2023) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-023-01397-7 · Cited by 20 · see citing works

Alterations of multiple alveolar macrophage states in chronic obstructive pulmonary diseasePreprint

Bassler, K. E., Fujii, W., Kapellos, T. S., Horne, A., Reiz, B., Dudkin, E., Luecken, M. D., Reusch, N., Osei-Sarpong, C., Warnat‐Herresthal, S., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.05.28.121541 · Cited by 16 · see citing works

Blood-based analyses of cancer: Circulating myeloid-derived suppressor cells – is a new era coming?

Okła, K., Wertel, I., Wawruszak, A., Bobiński, M. S., & Kotarski, J. (2018) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408363.2018.1477729 · Cited by 17 · see citing works

CRISPR Technique Incorporated with Single-Cell RNA Sequencing for Studying Hepatitis B Infection

Le, C., Liu, Y., López-Orozco, J., Joyce, M., Le, X. C., & Tyrrell, D. L. (2021) · Analytical Chemistry · doi:10.1021/acs.analchem.1c02227 · Cited by 16 · see citing works

Toward uncharted territory of cellular heterogeneity: advances and applications of single-cell RNA-seq

Lieberman, B., Kusi, M., Hung, C., Chou, C., Ning, H., Ho, Y., Taverna, J. A., Huang, T. H. ‐., & Chen, C. (2020) · Journal of Translational Genetics and Genomics · doi:10.20517/jtgg.2020.51 · Cited by 15 · see citing works

High-Dimensional Single-Cell Transcriptomics in Melanoma and Cancer Immunotherapy

Quek, C. Y. J., Bai, X., Long, G. V., Scolyer, R. A., & Wilmott, J. S. (2021) · Genes · doi:10.3390/genes12101629 · Cited by 16 · see citing works

Single‐cell transcriptomics reveals prominent expression of IL‐14, IL‐18, and IL‐32 in psoriasis

Frost, B., Schmidt, M., Klein, B., Loeffler‐Wirth, H., Krohn, K., Reidenbach, T., Binder, H., Stubenvoll, A., Simon, J. C., Saalbach, A., et al. (2023) · European Journal of Immunology · doi:10.1002/eji.202250354 · Cited by 14 · see citing works

DANCE: a deep learning library and benchmark platform for single-cell analysis

Ding, J., Liu, R., Wen, H., Tang, W., Li, Z., Venegas, J., Su, R., Molho, D., Jin, W., Wang, Y., et al. (2024) · Genome biology · doi:10.1186/s13059-024-03211-z · Cited by 14 · see citing works

Status and Potential of Single‐Cell Transcriptomics for Understanding Plant Development and Functional Biology

Iqbal, M. M., Hurgobin, B., Holme, A. L., Appels, R., & Kaur, P. (2020) · Cytometry Part A · doi:10.1002/cyto.a.24196 · Cited by 14 · see citing works

Paving the way for precision medicine v2.0 in intensive care by profiling necroinflammation in biofluids

Berghe, T. V., & Hoste, E. A. J. (2018) · Cell Death and Differentiation · doi:10.1038/s41418-018-0196-2 · Cited by 14 · see citing works

Age-Associated Modulation of TREM1/2-Expressing Macrophages Promotes Melanoma Progression and Metastasis

Scortegagna, M., Murad, R., Bina, P., Feng, Y., Porritt, R. A., Terskikh, A. V., Tian, X., Adams, P. D., Vuori, K., & Ronai, Z. A. (2025) · Cancer Research · doi:10.1158/0008-5472.can-24-4317 · Cited by 13 · see citing works

Visual Genomics Analysis Studio as a Tool to Analyze Multiomic Data

Hertzman, R. J., Deshpande, P., Leary, S., Li, Y., Ram, R., Chopra, A., Cooper, D., Watson, M. W., Palubinsky, A. M., Mallal, S. A., et al. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.642012 · Cited by 13 · see citing works

Shifting Gears in Precision Oncology—Challenges and Opportunities of Integrative Data Analysis

Noh, K., Buettner, R., & Klein, S. (2021) · Biomolecules · doi:10.3390/biom11091310 · Cited by 12 · see citing works

Single-cell transcriptome analysis identifies a novel tumor-associated macrophage subtype predicting better prognosis in pancreatic ductal adenocarcinoma

Wang, X., Li, D., Zhu, B., & Hua, Z. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1466767 · Cited by 12 · see citing works

Whispering Gallery Mode Micro/Nanolasers for Intracellular Probing at Single Cell Resolution

Fu, Y., Lin, S., & Wang, X. (2024) · ACS Sensors · doi:10.1021/acssensors.4c01634 · Cited by 12 · see citing works

The Power of ONE: Immunology in the Age of Single Cell Genomics

Amit, I. (2019) · Blood · doi:10.1182/blood-2019-121048

Abstract IA07: The Power of ONE: Immunology in the age of single cell genomics

Amit, I. (2022) · Cancer Immunology Research · doi:10.1158/2326-6074.tumimm22-ia07

Abstract IA17: The power of ONE: Immunology in the age of single cell genomics

Amit, I. (2022) · Cancer Immunology Research · doi:10.1158/2326-6074.tumimm21-ia17

Single-cell immunology: Past, present, and future

Ginhoux, F., Yalin, A., Dutertre, C., & Amit, I. (2022) · Immunity · doi:10.1016/j.immuni.2022.02.006 · Cited by 93 · see citing works

Single-Cell Genomics: Approaches and Utility in Immunology

Neu, K. E., Tang, Q., Wilson, P. C., & Khan, A. A. (2017) · Trends in Immunology · doi:10.1016/j.it.2016.12.001 · Cited by 67 · see citing works