Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue

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Metabolism and Metabolic Disorders and the Microbiome: The Intestinal Microbiota Associated With Obesity, Lipid Metabolism, and Metabolic Health—Pathophysiology and Therapeutic Strategies

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Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus

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Butyrate in Energy Metabolism: There Is Still More to Learn

Zhang, L., Liu, C.-D., Jiang, Q., & Yin, Y. (2021) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2020.12.003 · Cited by 370 · see citing works

The Effects of Temperature on Animal Gut Microbiomes

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Role of the gut-brain axis in energy and glucose metabolism

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A systematic framework for understanding the microbiome in human health and disease: from basic principles to clinical translation

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Demystifying the manipulation of host immunity, metabolism, and extraintestinal tumors by the gut microbiome

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PARPs in lipid metabolism and related diseases

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Inter‐organ communication: a gatekeeper for metabolic health

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The evolving view of thermogenic adipocytes — ontogeny, niche and function

Shamsi, F., Wang, C.-H., & Tseng, Y.-H. (2021) · Nature Reviews Endocrinology · doi:10.1038/s41574-021-00562-6 · Cited by 154 · see citing works

Antidiabetic Effects of Gegen Qinlian Decoction via the Gut Microbiota are Attributable to Its Key Ingredient Berberine

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Butyrate to combat obesity and obesity‐associated metabolic disorders: Current status and future implications for therapeutic use

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Emerging concepts in intestinal immune control of obesity-related metabolic disease

Khan, S. M., Luck, H., Winer, S., & Winer, D. A. (2021) · Nature Communications · doi:10.1038/s41467-021-22727-7 · Cited by 150 · see citing works

Interactions between dietary flavonoids and the gut microbiome: a comprehensive review

Baky, M. H., Elshahed, M. S., Wessjohann, L. A., & Farag, M. A. (2021) · British Journal Of Nutrition · doi:10.1017/s0007114521003627 · Cited by 145 · see citing works

Mechanisms of Weight Loss After Obesity Surgery

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Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity

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TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-Butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice

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Metabolic control by the microbiome

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The role of the microbiota in human genetic adaptation

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Blowing Hot and Cold: Body Temperature and the Microbiome

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The gut microbiota modulates both browning of white adipose tissue and the activity of brown adipose tissue

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Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity

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An update on brown adipose tissue and obesity intervention: Function, regulation and therapeutic implications

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LSD1 mediates microbial metabolite butyrate-induced thermogenesis in brown and white adipose tissue

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Indoleacrylic acid produced by Parabacteroides distasonis alleviates type 2 diabetes via activation of AhR to repair intestinal barrier

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The Metabolic Role and Therapeutic Potential of the Microbiome

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The role of ADP-ribose metabolism in metabolic regulation, adipose tissue differentiation, and metabolismPreprint

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Butyrate: A potential mediator of obesity and microbiome via different mechanisms of actions

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Gut Microbiota and Host Thermoregulation in Response to Ambient Temperature Fluctuations

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Switching on the furnace: Regulation of heat production in brown adipose tissue

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The Role of the Gut Microbiome in Energy Balance With a Focus on the Gut-Adipose Tissue Axis

Han, X., & Kang, S. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00297 · Cited by 82 · see citing works

Association of Gut Microbiota With Metabolism in Rainbow Trout Under Acute Heat Stress

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A big-data approach to understanding metabolic rate and response to obesity in laboratory mice

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Dissociation of Adaptive Thermogenesis from Glucose Homeostasis in Microbiome-Deficient Mice

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Intestinal AMPK modulation of microbiota mediates crosstalk with brown fat to control thermogenesis

Zhang, E., Jin, L., Wang, Y., Tu, J., Zheng, R., Ding, L., Fang, Z., Fan, M., Al-Abdullah, I., Natarajan, R., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28743-5 · Cited by 76 · see citing works

Walnut green husk polysaccharides prevent obesity, chronic inflammatory responses, nonalcoholic fatty liver disease and colonic tissue damage in high-fat diet fed rats

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Surviving winter on the Qinghai-Tibetan Plateau: Pikas suppress energy demands and exploit yak feces to survive winter

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Butyrate and obesity: Current research status and future prospect

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Local and systemic effects of microbiome‐derived metabolites

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Porcine gut microbiota in mediating host metabolic adaptation to cold stress

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Allicin‐induced host‐gut microbe interactions improves energy homeostasis

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Gut microbiota in dementia. Critical review of novel findings and their potential application

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Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota

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Deciphering the Anti-obesity Benefits of Resveratrol: The “Gut Microbiota-Adipose Tissue” Axis

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A new paradigm for a new simple chemical: butyrate & immune regulation

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Substrate Utilization by Brown Adipose Tissue: What’s Hot and What’s Not?

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Membrane Protein Amuc_1100 Derived from Akkermansia muciniphila Facilitates Lipolysis and Browning <i>via</i> Activating the AC3/PKA/HSL Pathway

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The microbiome-adipose tissue axis in systemic metabolism

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Cross-Talk Between Gut Microbiota and Adipose Tissues in Obesity and Related Metabolic Diseases

Wu, D., Wang, H., Xie, L., & Hu, F. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.908868 · Cited by 61 · see citing works

The microbiota and immune‐mediated diseases: Opportunities for therapeutic intervention

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Itaconate protects ferroptotic neurons by alkylating GPx4 post stroke

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Constant Light Exposure Alters Gut Microbiota and Promotes the Progression of Steatohepatitis in High Fat Diet Rats

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Quercetin activates energy expenditure to combat metabolic syndrome through modulating gut microbiota-bile acids crosstalk in mice

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Fu Brick Tea Polysaccharides Prevent Obesity via Gut Microbiota-Controlled Promotion of Adipocyte Browning and Thermogenesis

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A Song of Ice and Fire: Cold and Hot Properties of Traditional Chinese Medicines

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The Gut Microbiome Modulates Body Temperature Both in Sepsis and Health

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Immune Regulation of Metabolic Homeostasis by Helminths and Their Molecules

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Distinctive anti-inflammatory effects of resveratrol, dihydroresveratrol, and 3-(4-hydroxyphenyl)-propionic acid on DSS-induced colitis in pseudo-germ-free mice

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Microbiome‐immune‐metabolic axis in the epidemic of childhood obesity: Evidence and opportunities

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Communication between the gut microbiota and peripheral nervous system in health and chronic disease

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Metabolic reconstitution of germ-free mice by a gnotobiotic microbiota varies over the circadian cycle

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Fecal transplant from myostatin deletion pigs positively impacts the gut-muscle axis

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Pleurotus Ostreatus Ameliorates Obesity by Modulating the Gut Microbiota in Obese Mice Induced by High-Fat Diet

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Inhibiting macrophage-derived lactate transport restores cGAS–STING signalling and enhances antitumour immunity in glioblastoma

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Differential effects of synthetic psychoactive cathinones and amphetamine stimulants on the gut microbiome in mice

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Leptin mediates postprandial increases in body temperature through hypothalamus–adrenal medulla–adipose tissue crosstalk

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FGF15/19 is required for adipose tissue plasticity in response to thermogenic adaptations

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Brown adipose tissue is the key depot for glucose clearance in microbiota depleted mice

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Polysaccharide from Ziyang Selenium-Enriched Green Tea Prevents Obesity and Promotes Adipose Thermogenesis via Modulating the Gut Microbiota

Li, D., Cheng, Y., Zeng, X., Li, Y., Xia, Z., Yang, X., & Ren, D. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c04193 · Cited by 38 · see citing works

Ecophysiology and interactions of a taurine-respiring bacterium in the mouse gut

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Beige Adipocyte as the Flame of White Adipose Tissue: Regulation of Browning and Impact of Obesity

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Transcriptome analysis reveals the molecular regulatory network of muscle development and meat quality in Sunit lamb supplemented with dietary probiotic

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Effects of multi-organ crosstalk on the physiology and pathology of adipose tissue

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Genistein improves glucose metabolism and promotes adipose tissue browning through modulating gut microbiota in mice

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Naringin ameliorates obesity via stimulating adipose thermogenesis and browning, and modulating gut microbiota in diet-induced obese mice

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Adipocyte Mitochondria: Deciphering Energetic Functions across Fat Depots in Obesity and Type 2 Diabetes

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Keys to the switch of fat burning: stimuli that trigger the uncoupling protein 1 (UCP1) activation in adipose tissue

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Manipulation of Dietary Amino Acids Prevents and Reverses Obesity in Mice Through Multiple Mechanisms That Modulate Energy Homeostasis

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Chronic cold environment regulates rheumatoid arthritis through modulation of gut microbiota-derived bile acids

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Farnesoid X receptor is an effective target for modulating lipid accumulation in grass carp, Ctenopharyngodon idella

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Zeaxanthin ameliorates obesity by activating the β3-adrenergic receptor to stimulate inguinal fat thermogenesis and modulating the gut microbiota

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Do Bariatric Surgeries Enhance Brown/Beige Adipose Tissue Thermogenesis?

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Human torpor: translating insights from nature into manned deep space expedition

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An Update on the Role and Potential Molecules in Relation to Ruminococcus gnavus in Inflammatory Bowel Disease, Obesity and Diabetes Mellitus

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The role of the gut microbiome in the association between habitual anthocyanin intake and visceral abdominal fat in population-level analysis

Jennings, A., Koch, M., Jensen, M. K., Bang, C., Kassubek, J., Müller, H.-P., Nöthlings, U., Franke, A., Lieb, W., & Cassidy, A. (2019) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqz299 · Cited by 31 · see citing works

Naringenin activates beige adipocyte browning in high fat diet-fed C57BL/6 mice by shaping the gut microbiota

Zhang, S., Li, J., Shi, X., Tan, X., & Si, Q. (2022) · Food & Function · doi:10.1039/d2fo01610a · Cited by 31 · see citing works

Cold exposure, gut microbiota and health implications: A narrative review

Zhou, E., Zhang, L., He, L., Xiao, Y., Zhang, K., & Luo, B. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.170060 · Cited by 33 · see citing works

Alterations in co-abundant bacteriome in colorectal cancer and its persistence after surgery: a pilot study

Png, C. W., Chua, Y. K., Law, J.-H., Zhang, Y., & Tan, K. (2022) · Scientific Reports · doi:10.1038/s41598-022-14203-z · Cited by 29 · see citing works

Bifidobacterium longum DS0956 and Lactobacillus rhamnosus DS0508 culture-supernatant ameliorate obesity by inducing thermogenesis in obese-mice

Hossain, M. M., Park, D., Rahman, M. S., Ki, S. J., Lee, Y. R., Imran, K. M., Yoon, D., Heo, J.-Y., Lee, T.-J., & Kim, Y. S. (2020) · Beneficial Microbes · doi:10.3920/bm2019.0179 · Cited by 29 · see citing works

Implication of gut microbiota in the physiology of rats intermittently exposed to cold and hypobaric hypoxia

Ramos‐Romero, S., Santocildes, G., Piñol‐Piñol, D., Rosés, C., Pagés, T., Hereu, M., Amézqueta, S., Torrella, J. R., Torres, J. L., & Viscor, G. (2020) · PLoS ONE · doi:10.1371/journal.pone.0240686 · Cited by 29 · see citing works

Structural changes of butyrylated lotus seed starch and its impact on the gut microbiota of rat in vitro fermentation

Li, X., Chen, W., Gao, J., Gao, W., Zhang, Y., Zeng, H., & Zheng, B. (2023) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2023.108501 · Cited by 28 · see citing works

Lifelong dietary omega-3 fatty acid suppresses thrombotic potential through gut microbiota alteration in aged mice

Saravi, S. S. S., Bonetti, N. R., Pugin, B., Constancias, F., Pasterk, L., Gobbato, S., Akhmedov, A. T., Liberale, L., Lüscher, T. F., Camici, G. G., et al. (2021) · iScience · doi:10.1016/j.isci.2021.102897 · Cited by 28 · see citing works

Ectotherm heat tolerance and the microbiome: current understanding, future directions and potential applications

Fontaine, S. S., & Kohl, K. D. (2023) · Journal of Experimental Biology · doi:10.1242/jeb.245761 · Cited by 27 · see citing works

Intercellular and inter-organ crosstalk in browning of white adipose tissue: molecular mechanism and therapeutic complications

Cheong, L. Y., & Xu, A. (2021) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjab038 · Cited by 27 · see citing works

Thermo-TRPs and gut microbiota are involved in thermogenesis and energy metabolism during low temperature exposure of obese mice

Wen, J., Bo, T., Zhang, X., Wang, Z., & Wang, D. (2020) · Journal of Experimental Biology · doi:10.1242/jeb.218974 · Cited by 26 · see citing works

Calorie restriction and calorie dilution have different impacts on body fat, metabolism, behavior, and hypothalamic gene expression

Liu, X., Jin, Z., Summers, S., Derous, D., Li, M., Li, B., Li, L., & Speakman, J. R. (2022) · Cell Reports · doi:10.1016/j.celrep.2022.110835 · Cited by 26 · see citing works

Gut mucosal and adipose tissues as health targets of the immunomodulatory mechanisms of probiotics

Ashaolu, T. J., & Fernández‐Tomé, S. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.04.040 · Cited by 25 · see citing works

Depletion of gut microbiota influents glucose metabolism and hyperandrogenism traits of mice with PCOS induced by letrozole

Li, Y., Zhu, Y., Li, D., Liu, W., Zhang, Y., Liu, W., Zhang, C., & Tao, T. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1265152 · Cited by 25 · see citing works

The gut microbiota modulates both browning of white adipose tissue and the activity of brown adipose tissue

Moreno‐Navarrete, J. M., & Fernández‐Real, J. M. (2019) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-019-09523-x · Cited by 106 · see citing works

Microbiota depletion promotes browning of white adipose tissue and reduces obesity

Suárez-Zamorano, N., Fabbiano, S., Chevalier, C., Stojanović, O., Colin, D. J., Stevanović, A., Veyrat-Durebex, C., Tarallo, V., Rigo, D., Germain, S., et al. (2015) · Nature Medicine · doi:10.1038/nm.3994 · Cited by 403 · see citing works

Gut microbiota, brown adipose tissue whitening, and obesity: nutritional modulators and metabolic crosstalk

Ghodraty, M., Fekri, M., Kiani, M., Zadegan, S. E., Rezaei, S. A., Gilani, S. S. M., Varkiani, M. M., Ghafouri, A., Mehrnia, N., Amudi, M., et al. (2026) · Nutrition & Metabolism · doi:10.1186/s12986-026-01152-x

LSD1 mediates microbial metabolite butyrate-induced thermogenesis in brown and white adipose tissue

Wang, D., Liu, C.-D., Li, H., Tian, M.-L., Pan, J., Shu, G., Jiang, Q., Yin, Y., & Zhang, L. (2019) · Metabolism · doi:10.1016/j.metabol.2019.154011 · Cited by 99 · see citing works

Effect of Gut Microbiota Eradication on Adaptive Thermogenesis in Mice

Beserra, B. T. S., Silva, J. D. C., Oliveira, F. C. B., Ribeiro, C. M., Pereira, S. A., Neves, F. D. A. R., Coêlho, M. S., & Amato, A. A. (2017) · The FASEB Journal · doi:10.1096/fasebj.31.1_supplement.886.3