Chronic jet-lag increases mortality in aged mice
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Weekly 6-h phase advances and delays significantly hasten mortality in mice.
“Weekly 6-h phase advances and delays—experimental models applicable to shift work—significantly hasten mortality in mice (Davidson et al., 2006).”
From The impact of the circadian timing system on cardiovascular and metabolic function (2012) · cites this paper as Davidson et al., 2006
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- Authors
- Davidson, A. J., Sellix, M. T., Daniel, J., Yamazaki, S., Menaker, M., & Block, G. D.
- Affiliations
- University of Virginia (US)
- Corresponding author
- Block, G.D.
- Venue
- Current Biology
- Publisher
- Elsevier BV
- Published
- 2006-11
- Volume
- 16
- Issue
- 21
- Pages
- R914-R916
- ISSN
- 0960-9822 (ISSN-L)
- PMC
- PMC1635966
- OpenAlex
- W2078978479
- Cited by
- 427
- References
- 11
- Citations by year
- 2026: 8 · 2025: 18 · 2024: 21 · 2023: 18 · 2022: 25 · 2021: 24 · 2020: 29 · 2019: 26 · 2018: 22 · 2017: 19 · 2016: 18 · 2015: 22 · 2014: 17 · 2013: 36 · 2012: 20
- FWCI
- 7.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Current Biology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- Funders
- National Institute of Mental Health (RO1 MH062517, RO1 MH56647)
- National Institute on Aging (F32 AG22741-01)
- National Institute of Neurological Disorders and Stroke (RO1 NS051278)
- National Space Biomedical Research Institute (NCC9-58-167)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Health Sciences › Medicine › Physiology › Spaceflight effects on biology
- Keywords
- circadian rhythm disruption, shift work, aging, mortality, biological clock, damage accumulation
- MeSH terms
- Aging, Animals, Chronic Disease, Light, Longevity, Male, Mice, Inbred C57BL, Jet Lag Syndrome, Mice
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