Circadian Rhythms, the Molecular Clock, and Skeletal Muscle

Harfmann, Brianna D.; Schroder, Elizabeth A.; Esser, Karyn A.

doi:10.1177/0748730414561638

Cited by 211Circadian rhythm and melatoninMuscle Physiology and DisordersSleep and Work-Related Fatigue

Circadian Rhythms, the Molecular Clock, and Skeletal Muscle

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Harfmann, Brianna D., Schroder, Elizabeth A., Esser, Karyn A.·2015·Journal of Biological Rhythms

DOI 10.1177/0748730414561638PMC PMC4470613

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Abstract

Circadian rhythms are the approximate 24-h biological cycles that function to prepare an organism for daily environmental changes. They are driven by the molecular clock, a transcriptional:translational feedback mechanism that in mammals involves the core clock genes Bmal1, Clock, Per1/2, and Cry1/2. The molecular clock is present in virtually all cells of an organism. The central clock in the suprachiasmatic nucleus (SCN) has been well studied, but the clocks in the peripheral tissues, such as heart and skeletal muscle, have just begun to be investigated. Skeletal muscle is one of the largest organs in the body, comprising approximately 45% of total body mass. More than 2300 genes in skeletal muscle are expressed in a circadian pattern, and these genes participate in a wide range of functions, including myogenesis, transcription, and metabolism. The circadian rhythms of skeletal muscle can be entrained both indirectly through light input to the SCN and directly through time of feeding and activity. It is critical for the skeletal muscle molecular clock not only to be entrained to the environment but also to be in synchrony with rhythms of other tissues. When circadian rhythms are disrupted, the observed effects on skeletal muscle include fiber-type shifts, altered sarcomeric structure, reduced mitochondrial respiration, and impaired muscle function. Furthermore, there are detrimental effects on metabolic health, including impaired glucose tolerance and insulin sensitivity, which skeletal muscle likely contributes to considering it is a key metabolic tissue. These data indicate a critical role for skeletal muscle circadian rhythms for both muscle and systems health. Future research is needed to determine the mechanisms of molecular clock function in skeletal muscle, identify the means by which skeletal muscle entrainment occurs, and provide a stringent comparison of circadian gene expression across the diverse tissue system of skeletal muscle.

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Circadian clocks exist in virtually all cells including skeletal muscle and regulate certain metabolic and cell physiologic processes.
“Circadian clocks exist in virtually all cells in the body including skeletal muscles and is a ubiquitous mechanism that functions to temporarily regulate certain metabolic and cell physiologic processes (Harfmann et al., 2015).”
From Myosteatosis in the Context of Skeletal Muscle Function Deficit: An Interdisciplinary Workshop at the National Institute on Aging (2020) · cites this paper as Harfmann et al., 2015

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Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice
Turek, F. W., Joshu, C., Kohsaka, A., Lin, E., Ivanova, G., McDearmon, E., Laposky, A., Losee-Olson, S., Easton, A., Jensen, D. R., et al. (2005) · Science · doi:10.1126/science.1108750 · Cited by 2,485 · see citing works
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
Damiola, F., Le Minh, N., Preitner, N., Kornmann, B., Fleury-Olela, F., & Schibler, U. (2000) · Genes & Development · doi:10.1101/gad.183500 · Cited by 2,394 · see citing works
Adverse metabolic and cardiovascular consequences of circadian misalignment
Scheer, F. A. J. L., Hilton, M. F., Mantzoros, C. S., & Shea, S. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808180106 · Cited by 2,351 · see citing works
PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues
Yoo, S.-H., Yamazaki, S., Lowrey, P. L., Shimomura, K., Ko, C. H., Buhr, E. D., Siepka, S. M., Hong, H.-K., Oh, W. J., Yoo, O. J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308709101 · Cited by 2,329 · see citing works
Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock
Panda, S., Antoch, M. P., Miller, B. H., Su, A. I., Schook, A. C., Straume, M., Schultz, P. G., Kay, S. A., Takahashi, J. S., & Hogenesch, J. B. (2002) · Cell · doi:10.1016/s0092-8674(02)00722-5 · Cited by 2,272 · see citing works
The Orphan Nuclear Receptor REV-ERBα Controls Circadian Transcription within the Positive Limb of the Mammalian Circadian Oscillator
Preitner, N., Damiola, F., Luis-Lopez-Molina, Zakany, J., Duboule, D., Albrecht, U., & Schibler, U. (2002) · Cell · doi:10.1016/s0092-8674(02)00825-5 · Cited by 2,198 · see citing works
Pathogenesis of NIDDM. A balanced overview.
DeFronzo, R. A., Bonadonna, R. C., & Ferrannini, E. (1992) · Diabetes Care · doi:10.2337/diacare.15.3.318 · Cited by 2,085 · see citing works
Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α (PGC-1α): Transcriptional Coactivator and Metabolic Regulator
Puigserver, P., & Spiegelman, B. M. (2003) · Endocrine Reviews · doi:10.1210/er.2002-0012 · Cited by 2,076 · see citing works
Circadian Rhythms in Drinking Behavior and Locomotor Activity of Rats Are Eliminated by Hypothalamic Lesions
Stephan, F. K., & Zucker, I. (1972) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.69.6.1583 · Cited by 2,039 · see citing works
Role of the CLOCK Protein in the Mammalian Circadian Mechanism
Gekakis, N., Staknis, D., Nguyen, H. B., Davis, F. C., Wilsbacher, L. D., King, D. P., Takahashi, J. S., & Weitz, C. J. (1998) · Science · doi:10.1126/science.280.5369.1564 · Cited by 1,997 · see citing works
Resetting central and peripheral circadian oscillators in transgenic rats
Yamazaki, S., Numano, R., Abe, M., Hida, A., Takahashi, R.-I., Ueda, M., Block, G. D., Sakaki, Y., Menaker, M., & Tei, H. (2000) · Science · doi:10.1126/science.288.5466.682 · Cited by 1,907 · see citing works
Resetting of circadian time in peripheral tissues by glucocorticoid signaling
Balsalobre, A., Brown, S. A., Marcacci, L., Tronche, F., Kellendonk, C., Reichardt, H. M., Schütz, G., & Schibler, U. (2000) · Science · doi:10.1126/science.289.5488.2344 · Cited by 1,859 · see citing works
Transplanted Suprachiasmatic Nucleus Determines Circadian Period
Ralph, M. R., Foster, R. G., Davis, F. C., & Menaker, M. (1990) · Science · doi:10.1126/science.2305266 · Cited by 1,853 · see citing works
Entrainment of the circadian clock in the liver by feeding
Stokkan, K.-A., Yamazaki, S., Tei, H., Sakaki, Y., & Menaker, M. (2001) · Science · doi:10.1126/science.291.5503.490 · Cited by 1,800 · see citing works
MyoD or Myf-5 is required for the formation of skeletal muscle
Rudnicki, M. A., Schnegelsberg, P. N. J., Stead, R. H., Braun, T. W., Arnold, H.-H., & Jaenisch, R. (1993) · Cell · doi:10.1016/0092-8674(93)90621-v · Cited by 1,731 · see citing works
Mechanisms and functions of p38 MAPK signalling
Cuadrado, A., & Nebreda, Á. R. (2010) · Biochemical Journal · doi:10.1042/bj20100323 · Cited by 1,679 · see citing works
Mutagenesis and Mapping of a Mouse Gene, Clock , Essential for Circadian Behavior
Vitaterna, M. H., King, D. P., Chang, A.-M., Kornhauser, J. M., Lowrey, P. L., McDonald, J. D., Dove, W. F., Pinto, L. H., Turek, F. W., & Takahashi, J. S. (1994) · Science · doi:10.1126/science.8171325 · Cited by 1,632 · see citing works
Mop3 is an essential component of the master circadian pacemaker in mammals.
Bunger, M. K., Wilsbacher, L. D., Moran, S. M., Clendenin, C., Radcliffe, L. A., Hogenesch, J. B., Simon, M. C., Takahashi, J. S., & Bradfield, C. A. (2000) · Cell · doi:10.1016/s0092-8674(00)00205-1 · Cited by 1,621 · see citing works
mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
Kume, K., Zylka, M. J., Sriram, S., Shearman, L. P., Weaver, D. R., Jin, X., Maywood, E. S., Hastings, M. H., & Reppert, S. M. (1999) · Cell · doi:10.1016/s0092-8674(00)81014-4 · Cited by 1,617 · see citing works
The genetics of mammalian circadian order and disorder: implications for physiology and disease
Takahashi, J. S., Hong, H.-K., Ko, C. H., & McDearmon, E. L. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2430 · Cited by 1,611 · see citing works
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes
Marcheva, B., Ramsey, K. M., Buhr, E. D., Kobayashi, Y., Su, H., Ko, C. H., Ivanova, G., Omura, C., Mo, S., Vitaterna, M. H., et al. (2010) · Nature · doi:10.1038/nature09253 · Cited by 1,525 · see citing works
Extensive and divergent circadian gene expression in liver and heart
Storch, K.-F., Lipan, O., Leykin, I., Viswanathan, N., Davis, F. C., Wong, W. H., & Weitz, C. J. (2002) · Nature · doi:10.1038/nature744 · Cited by 1,509 · see citing works
Exogenous and Endogenous Components in Circadian RhythmsPreprint
Aschoff, J. (1960) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1960.025.01.004 · Cited by 1,487 · see citing works
Transcriptional architecture and chromatin landscape of the core circadian clock in mammals
Koike, N., Yoo, S.-H., Huang, H.-C., Kumar, V., Lee, C., Kim, T.-K., & Takahashi, J. S. (2012) · Science · doi:10.1126/science.1226339 · Cited by 1,464 · see citing works
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control
Nakahata, Y., Kaluzova, M., Grimaldi, B., Sahar, S., Hirayama, J., Chen, D., Guarente, L. P., & Sassone-Corsi, P. (2008) · Cell · doi:10.1016/j.cell.2008.07.002 · Cited by 1,427 · see citing works
Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms
Horst, G. T. J. V. D., Muijtjens, M., Kobayashi, K., Takano, R., Kanno, S.-I., Takao, M., Wit, J. D., Verkerk, A., Eker, A. P. M., Leenen, D. V., et al. (1999) · Nature · doi:10.1038/19323 · Cited by 1,402 · see citing works
SIRT1 regulates circadian clock gene expression through PER2 deacetylation
Asher, G., Gatfield, D., Stratmann, M., Reinke, H., Dibner, C., Kreppel, F., Mostoslavsky, R., Alt, F. W., & Schibler, U. (2008) · Cell · doi:10.1016/j.cell.2008.06.050 · Cited by 1,376 · see citing works
Interacting molecular loops in the mammalian circadian clock
Shearman, L. P., Sriram, S., Weaver, D. R., Maywood, E. S., Chaves, I., Zheng, B., Kume, K., Lee, C. C., van der, G. T. J., Horst, et al. (2000) · Science · doi:10.1126/science.288.5468.1013 · Cited by 1,367 · see citing works
Health disorders of shift workers
Knutsson, A. (2003) · Occupational Medicine · doi:10.1093/occmed/kqg048 · Cited by 1,218 · see citing works
Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock
Kondratov, R. V., Kondratova, A. A., Gorbacheva, V. Y., Vykhovanets, O. V., & Antoch, M. P. (2006) · Genes & Development · doi:10.1101/gad.1432206 · Cited by 1,188 · see citing works
Posttranslational Mechanisms Regulate the Mammalian Circadian Clock
Lee, C., Etchegaray, J., Cagampang, F. R. A., Loudon, A. S. I., & Reppert, S. M. (2001) · Cell · doi:10.1016/s0092-8674(01)00610-9 · Cited by 1,158 · see citing works
Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD + Biosynthesis
Ramsey, K. M., Yoshino, J., Brace, C. S., Abrassart, D., Kobayashi, Y., Marcheva, B., Hong, H.-K., Chong, J. L., Buhr, E. D., Lee, C., et al. (2009) · Science · doi:10.1126/science.1171641 · Cited by 1,126 · see citing works
A Functional Genomics Strategy Reveals Rora as a Component of the Mammalian Circadian Clock
Sato, T. K., Panda, S., Miraglia, L. J., Reyes, T. M., Rudic, R. D., McNamara, P., Naik, K. A., FitzGerald, G. A., Kay, S. A., & Hogenesch, J. B. (2004) · Neuron · doi:10.1016/j.neuron.2004.07.018 · Cited by 1,115 · see citing works
Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
Kelley, D. E., Goodpaster, B., Wing, R. R., & Simoneau, J.-A. (1999) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1999.277.6.e1130 · Cited by 1,096 · see citing works
BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis
Rudic, R. D., McNamara, P., Curtis, A.-M., Boston, R. C., Panda, S., Hogenesch, J. B., & FitzGerald, G. A. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020377 · Cited by 1,059 · see citing works
Mammalian circadian biology: elucidating genome-wide levels of temporal organization
Lowrey, P. L., & Takahashi, J. S. (2004) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.5.061903.175925 · Cited by 976 · see citing works
AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation
Lamia, K. A., Sachdeva, U. M., DiTacchio, L., Williams, E. C., Alvarez, J. G., Egan, D. F., Vasquez, D. S., Juguilon, H., Panda, S., Shaw, R. J., et al. (2009) · Science · doi:10.1126/science.1172156 · Cited by 958 · see citing works
Skeletal muscle attenuation determined by computed tomography is associated with skeletal muscle lipid content
Goodpaster, B. H., Kelley, D. E., Thaete, F. L., He, J., & Ross, R. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.1.104 · Cited by 956 · see citing works
Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27 485 people
Karlsson, B., Knutsson, A., & Lindahl, B. (2001) · Occupational and Environmental Medicine · doi:10.1136/oem.58.11.747 · Cited by 924 · see citing works
Human Sleep: Its Duration and Organization Depend on Its Circadian Phase
Czeisler, C. A., Weitzman, E. D., Moore-Ede, M. C., Zimmerman, J. C., & Knauer, R. S. (1980) · Science · doi:10.1126/science.7434029 · Cited by 903 · see citing works
Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock.
Zheng, B., Albrecht, U., Kaasik, K., Sage, M., Lu, W., Vaishnav, S., Li, Q., Sun, Z. S., Eichele, G., Bradley, A., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00380-4 · Cited by 900 · see citing works
Circadian Regulator CLOCK Is a Histone Acetyltransferase
Doi, M., Hirayama, J., & Sassone‐Corsi, P. (2006) · Cell · doi:10.1016/j.cell.2006.03.033 · Cited by 890 · see citing works
Muscle‐derived interleukin‐6: mechanisms for activation and possible biological roles
FEBBRAIO, M. A., & PEDERSEN, B. K. (2002) · The FASEB Journal · doi:10.1096/fj.01-0876rev · Cited by 875 · see citing works
Three period Homologs in Mammals: Differential Light Responses in the Suprachiasmatic Circadian Clock and Oscillating Transcripts Outside of Brain
Zylka, M. J., Shearman, L. P., Weaver, D. R., & Reppert, S. M. (1998) · Neuron · doi:10.1016/s0896-6273(00)80492-4 · Cited by 865 · see citing works
Post-translational modifications regulate the ticking of the circadian clock
Gallego, M., & Virshup, D. M. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2106 · Cited by 863 · see citing works
Positional Syntenic Cloning and Functional Characterization of the Mammalian Circadian Mutation tau
Lowrey, P. L., Shimomura, K., Antoch, M. P., Yamazaki, S., Zemenides, P. D., Ralph, M. R., Menaker, M., & Takahashi, J. S. (2000) · Science · doi:10.1126/science.288.5465.483 · Cited by 860 · see citing works
Circadian food-anticipatory activity: Formal models and physiological mechanisms
Mistlberger, R. E. (1994) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(94)90023-x · Cited by 857 · see citing works
A transcription factor response element for gene expression during circadian night
Ueda, H. R., Chen, W., Adachi, A. A., Wakamatsu, H., Hayashi, S., Takasugi, T., Nagano, M., Nakahama, K., Suzuki, Y., Sugano, S., et al. (2002) · Nature · doi:10.1038/nature00906 · Cited by 850 · see citing works
The basic-helix–loop–helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors
Hogenesch, J. B., Gu, Y.-Z., Jain, S. R., & Bradfield, C. A. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.10.5474 · Cited by 781 · see citing works
The circuitry of a master switch: Myod and the regulation of skeletal muscle gene transcription
Tapscott, S. J. (2005) · Development · doi:10.1242/dev.01874 · Cited by 766 · see citing works
Differential Control of Bmal1 Circadian Transcription by REV-ERB and ROR Nuclear Receptors
Guillaumond, F., Dardente, H., Giguère, V., & Cermakian, N. (2005) · Journal of Biological Rhythms · doi:10.1177/0748730405277232 · Cited by 762 · see citing works
The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome
Petersen, K. F., Dufour, S., Savage, D. B., Bilz, S., Solomon, G., Yonemitsu, S., Cline, G. W., Befroy, D., Zemany, L., Kahn, B. B., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0705408104 · Cited by 759 · see citing works
Molecular components of the mammalian circadian clock
Buhr, E. D., & Takahashi, J. S. (2013) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-25950-0_1 · Cited by 738 · see citing works
Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression
Welsh, D. K., Yoo, S.-H., Liu, A. C., Takahashi, J. S., & Kay, S. A. (2004) · Current Biology · doi:10.1016/j.cub.2004.11.057 · Cited by 726 · see citing works
Brain-derived neurotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP-activated protein kinase
Matthews, V. B., Åström, M.-B., Chan, M. H. S., Bruce, C. R., Krabbe, K. S., Prelovsek, O., Åkerström, T., Yfanti, C., Broholm, C., Mortensen, O. H., et al. (2009) · Diabetologia · doi:10.1007/s00125-009-1364-1 · Cited by 722 · cited 1× · see citing works
“Other identified myokines include IL-8, IL-15, and brain-derived neurotrophic factor and Irisin (Febbraio and Pedersen, 2002; Nielsen and Pedersen, 2007; Matthews et al., 2009).”
The mPer2 gene encodes a functional component of the mammalian circadian clock
Zheng, B., Larkin, D. W., Albrecht, U., Sun, Z. S., Sage, M., Eichele, G., Lee, C. C., & Bradley, A. (1999) · Nature · doi:10.1038/22118 · Cited by 718 · see citing works
A Mutation of the Circadian System in Golden Hamsters
Ralph, M. R., & Menaker, M. (1988) · Science · doi:10.1126/science.3413487 · Cited by 700 · see citing works
Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network
Liu, A. C., Welsh, D. K., Ko, C. H., Tran, H. G., Zhang, E. E., Priest, A. A., Buhr, E. D., Singer, O., Meeker, K., Verma, I. M., et al. (2007) · Cell · doi:10.1016/j.cell.2007.02.047 · Cited by 694 · see citing works
Rhythmic histone acetylation underlies transcription in the mammalian circadian clock
Etchegaray, J.-P., Lee, C., Wade, P. A., & Reppert, S. M. (2003) · Nature · doi:10.1038/nature01314 · Cited by 679 · see citing works
Functional Identification of the Mouse Circadian Clock Gene by Transgenic BAC Rescue
Antoch, M. P., Song, E.-J., Chang, A., Vitaterna, M. H., Zhao, Y., Wilsbacher, L. D., Sangoram, A. M., King, D. P., Pinto, L. H., & Takahashi, J. S. (1997) · Cell · doi:10.1016/s0092-8674(00)80246-9 · Cited by 665 · see citing works
Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism
Liu, C., Li, S., Liu, T., Borjigin, J., & Lin, J. D. (2007) · Nature · doi:10.1038/nature05767 · Cited by 643 · see citing works
Impaired Regulation of Hepatic Glucose Production in Mice Lacking the Forkhead Transcription Factor Foxo1 in Liver
Matsumoto, M., Pocai, A., Rossetti, L., DePinho, R. A., & Accili, D. (2007) · Cell Metabolism · doi:10.1016/j.cmet.2007.08.006 · Cited by 616 · see citing works
Sir2 Regulates Skeletal Muscle Differentiation as a Potential Sensor of the Redox State
Fulco, M., Schiltz, R. L., Iezzi, S., King, M. T., Zhao, P., Kashiwaya, Y., Hoffman, E. P., Veech, R. L., & Sartorelli, V. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00226-0 · Cited by 590 · see citing works
The mammalian basic helix–loop–helix/PAS family of transcriptional regulators
Kewley, R. J., Whitelaw, M. L., & Chapman‐Smith, A. (2003) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(03)00211-5 · Cited by 590 · see citing works
Rhythms of Mammalian Body Temperature Can Sustain Peripheral Circadian Clocks
Brown, S. A., Zumbrunn, G., Fleury-Olela, F., Preitner, N., & Schibler, U. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01145-4 · Cited by 589 · see citing works
Melanopsin in cells of origin of the retinohypothalamic tract
Gooley, J. J., Lü, J., Chou, T. C., Scammell, T. E., & Saper, C. B. (2001) · Nature Neuroscience · doi:10.1038/nn768 · Cited by 586 · see citing works
Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus
Hara, R., Wan, K., Wakamatsu, H., Aida, R., Moriya, T., Akiyama, M., & Shibata, S. (2001) · Genes to Cells · doi:10.1046/j.1365-2443.2001.00419.x · Cited by 569 · cited 3× · see citing works
“In liver, this was shown to be independent of SCN input, since timerestricted feeding prevented the shift of the clock genes when the mice were exposed to a 7-h light:dark cycle advance (Hara et al., 2001).”
Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis
Zhang, E. E., Liu, Y., Dentin, R., Pongsawakul, P. Y., Liu, A. C., Hirota, T., Nusinow, D. A., Sun, X., Landais, S., Kodama, Y., et al. (2010) · Nature Medicine · doi:10.1038/nm.2214 · Cited by 567 · see citing works
Circadian rhythmicity restored by neural transplant. Immunocytochemical characterization of the graft and its integration with the host brain
Lehman, M. N., Silver, R., Gladstone, W., Kahn, R. M., Gibson, M., & Bittman, E. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-06-01626.1987 · Cited by 560 · see citing works
Nuclear Receptor Rev-erbα Is a Critical Lithium-Sensitive Component of the Circadian Clock
Yin, L., Wang, J., Klein, P. S., & Lazar, M. A. (2006) · Science · doi:10.1126/science.1121613 · Cited by 556 · see citing works
Titin: major myofibrillar components of striated muscle.
Wang, K., McClure, J., & Tu, A. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.8.3698 · Cited by 546 · see citing works
Circadian Mutant Overtime Reveals F-box Protein FBXL3 Regulation of Cryptochrome and Period Gene Expression
Siepka, S. M., Yoo, S. H., Park, J., Song, W., Kumar, V., Hu, Y., Lee, C., & Takahashi, J. S. (2007) · Cell · doi:10.1016/j.cell.2007.04.030 · Cited by 536 · see citing works
Spectral sensitivity of a novel photoreceptive system mediating entrainment of mammalian circadian rhythms
Takahashi, J. S., DeCoursey, P. J., Bauman, L., & Menaker, M. (1984) · Nature · doi:10.1038/308186a0 · Cited by 528 · see citing works
CLOCK-mediated acetylation of BMAL1 controls circadian function
Hirayama, J., Sahar, S., Grimaldi, B., Tamaru, T., Takamatsu, K., Nakahata, Y., & Sassone‐Corsi, P. (2007) · Nature · doi:10.1038/nature06394 · Cited by 525 · see citing works
SCF Fbxl3 Controls the Oscillation of the Circadian Clock by Directing the Degradation of Cryptochrome Proteins
Busino, L., Bassermann, F. C., Maiolica, A., Lee, C., Nolan, P. M., Godinho, S. I. H., Draetta, G. F., & Pagano, M. (2007) · Science · doi:10.1126/science.1141194 · Cited by 509 · see citing works
Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation
Miller, B. H., McDearmon, E. L., Panda, S., Hayes, K. R., Zhang, J., Andrews, J. L., Antoch, M. P., Walker, J. R., Esser, K. A., Hogenesch, J. B., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611724104 · Cited by 509 · see citing works
Self-citation
Characterization of Peripheral Circadian Clocks in Adipose Tissues
Zvonic, S., Ptitsyn, A. A., Conrad, S. A., Scott, L. K., Floyd, Z. E., Kilroy, G. E., Wu, X., Goh, B. C. K., Mynatt, R. L., & Gimble, J. M. (2006) · Diabetes · doi:10.2337/diabetes.55.04.06.db05-0873 · Cited by 495 · see citing works
Control of Mammalian Circadian Rhythm by CKIε-Regulated Proteasome-Mediated PER2 Degradation
Eide, E. J., Woolf, M. F., Kang, H., Woolf, P., Hurst, W., Camacho, F., Vielhaber, E. L., Giovanni, A., & Virshup, D. M. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.7.2795-2807.2005 · Cited by 495 · see citing works
Glycogen synthase kinase 3: more than a namesake
Rayasam, G. V., Tulasi, V. K., Sodhi, R., Davis, J. A., & Ray, A. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2008.00085.x · Cited by 485 · see citing works
CLOCK and NPAS2 have overlapping roles in the suprachiasmatic circadian clock
DeBruyne, J. P., Weaver, D. R., & Reppert, S. M. (2007) · Nature Neuroscience · doi:10.1038/nn1884 · Cited by 484 · see citing works
Genome-Wide and Phase-Specific DNA-Binding Rhythms of BMAL1 Control Circadian Output Functions in Mouse Liver
Rey, G., Cesbron, F., Rougemont, J., Reinke, H., Brunner, M., & Naef, F. (2011) · PLoS Biology · doi:10.1371/journal.pbio.1000595 · Cited by 473 · see citing works
The After-Hours Mutant Reveals a Role for Fbxl3 in Determining Mammalian Circadian Period
Godinho, S. I. H., Maywood, E. S., Shaw, L. E., Tucci, V., Barnard, A. R., Busino, L., Pagano, M., Kendall, R., Quwailid, M. M., Romero, M. R., et al. (2007) · Science · doi:10.1126/science.1141138 · Cited by 468 · see citing works
Defining the regulatory networks for muscle development
Molkentin, J. D., & Olson, E. N. (1996) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(96)80066-9 · Cited by 463 · see citing works
Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock
Dyar, K. A., Ciciliot, S., Wright, L. E., Biensø, R. S., Tagliazucchi, G. M., Patel, V. R., Forcato, M., Paz, M. I. P., Gudiksen, A., Solagna, F., et al. (2014) · Molecular Metabolism · doi:10.1016/j.molmet.2013.10.005 · Cited by 454 · cited 3× · see citing works
“Loss of the core clock gene Bmal1 results in severe muscle pathology, including fiber-type shifts, decreased mitochondria, impaired mitochondrial respiration, altered sarcomeric structure, and debilitated function (Andrews et al., 2010; Dyar et al., 2014).”
Clocks not winding down: unravelling circadian networks
Zhang, E. E., & Kay, S. A. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2995 · Cited by 446 · see citing works
Molecular Bases of Circadian Rhythms
Harmer, S. L., Panda, S., & Kay, S. A. (2001) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.17.1.215 · Cited by 440 · see citing works
A clock shock: mouse CLOCK is not required for circadian oscillator function
DeBruyne, J. P., Noton, E., Lambert, C. M., Maywood, E. S., Weaver, D. R., & Reppert, S. M. (2006) · Neuron · doi:10.1016/j.neuron.2006.03.041 · Cited by 430 · see citing works
Chronic jet-lag increases mortality in aged mice
Davidson, A. J., Sellix, M. T., Daniel, J., Yamazaki, S., Menaker, M., & Block, G. D. (2006) · Current Biology · doi:10.1016/j.cub.2006.09.058 · Cited by 427 · see citing works
Mechanisms of Liver and Muscle Insulin Resistance Induced by Chronic High-Fat Feeding
Oakes, N. D., Cooney, G. J., Camilleri, S., Chisholm, D. J., & Kraegen, E. W. (1997) · Diabetes · doi:10.2337/diab.46.11.1768 · Cited by 414 · see citing works
Host Circadian Clock as a Control Point in Tumor Progression
Filipski, E. (2002) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/94.9.690 · Cited by 413 · see citing works
PGC-1α regulation by exercise training and its influences on muscle function and insulin sensitivity
Lira, V. A., Benton, C. R., Yan, Z., & Bonen, A. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00755.2009 · Cited by 412 · see citing works
LOCOMOTOR ACTIVITY AND NON‐PHOTIC INFLUENCES ON CIRCADIAN CLOCKS
Mrosovsky, N. (1996) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/j.1469-185x.1996.tb01278.x · Cited by 412 · see citing works
CLOCK and BMAL1 regulate MyoD and are necessary for maintenance of skeletal muscle phenotype and function
Andrews, J. L., Zhang, X., McCarthy, J. J., McDearmon, E. L., Hornberger, T. A., Russell, B., Campbell, K. S., Arbogast, S., Reid, M. B., Walker, J. R., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1014523107 · Cited by 389 · cited 8× · see citing works
“Specifically, a significant reduction in state III respiration (ADPstimulated, mmol O2/min/mg protein) in mitochondria isolated from gastrocnemius muscle was observed (Andrews et al., 2010).”
InfluentialSelf-citation
The art of entrainment
Roenneberg, T., Daan, S., & Merrow, M. (2003) · Journal of Biological Rhythms · doi:10.1177/0748730403018003001 · Cited by 387 · cited 2× · see citing works
“Entrainment occurs when the phase of the molecular clock is reset or modulated to be aligned with the timing of an environmental cue, such as light (Roenneberg et al., 2003).”
Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS)Preprint
Vanselow, K., Vanselow, J. T., Westermark, P. O., Reischl, S., Maier, B., Korte, T., Herrmann, A., Herzel, H., Schlösser, A., & Kramer, A. (2006) · Genes & Development · doi:10.1101/gad.397006 · Cited by 383 · see citing works
A Role for Glycogen Synthase Kinase-3β in the Mammalian Circadian Clock
Iitaka, C., Miyazaki, K., Akaike, T., & Ishida, N. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m503526200 · Cited by 373 · see citing works
Light and circadian rhythmicity regulate MAP kinase activation in the suprachiasmatic nuclei
Obrietan, K. H., Impey, S., & Storm, D. R. (1998) · Nature Neuroscience · doi:10.1038/3695 · Cited by 369 · see citing works
CircaDB: a database of mammalian circadian gene expression profiles
Pizarro, A., Hayer, K. E., Lahens, N. F., & Hogenesch, J. B. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks1161 · Cited by 367 · see citing works
Identification of the circadian transcriptome in adult mouse skeletal muscle
McCarthy, J. J., Andrews, J. L., McDearmon, E. L., Campbell, K. S., Barber, B. K., Miller, B. H., Walker, J. R., Hogenesch, J. B., Takahashi, J. S., & Esser, K. A. (2007) · Physiological Genomics · doi:10.1152/physiolgenomics.00066.2007 · Cited by 363 · see citing works
Self-citation
Mammalian Circadian Autoregulatory Loop
Sangoram, A. M., Sáez, L., Antoch, M. P., Gekakis, N., Staknis, D., Whiteley, A. R., Fruechte, E. M., Vitaterna, M. H., Shimomura, K., King, D. P., et al. (1998) · Neuron · doi:10.1016/s0896-6273(00)80627-3 · Cited by 355 · see citing works
Re-entrainment of circadian rhythms after phase-shifts of the Zeitgeber.
Aschoff, J., Hoffmann, K. H., Pohl, H. H., & Wever, R. A. (1975) · PubMed · Cited by 352 · see citing works
Coupling governs entrainment range of circadian clocks
Abraham, U., Granada, A. E., Westermark, P. O., Heine, M., Kramer, A., & Herzel, H. (2010) · Molecular Systems Biology · doi:10.1038/msb.2010.92 · Cited by 349 · see citing works
Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man
SCOTT, E. M., Carter, A. M., & Grant, P. J. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803778 · Cited by 344 · see citing works
Competing E3 Ubiquitin Ligases Govern Circadian Periodicity by Degradation of CRY in Nucleus and Cytoplasm
Yoo, S. H., Mohawk, J. A., Siepka, S. M., Shan, Y., Huh, S. K., Hong, H., Kornblum, I., Kumar, V., Koike, N., Xu, M., et al. (2013) · Cell · doi:10.1016/j.cell.2013.01.055 · Cited by 341 · see citing works
A Daily Rhythm in Glucose Tolerance
la Fleur, S. E., Kalsbeek, A., Wortel, J., Fekkes, M. L., & Buijs, R. M. (2001) · Diabetes · doi:10.2337/diabetes.50.6.1237 · Cited by 337 · see citing works
Promoter-Specific Regulation of MyoD Binding and Signal Transduction Cooperate to Pattern Gene Expression
Bergstrom, D. A., Penn, B. H., Strand, A. D., Perry, R. L., Rudnicki, M. A., & Tapscott, S. J. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00481-1 · Cited by 332 · see citing works
Loss of entrainment and anatomical plasticity after lesions of the hamster retinohypothalamic tract
Johnson, R. F., Moore, R. Y., & Morin, L. P. (1988) · Brain Research · doi:10.1016/0006-8993(88)90374-5 · Cited by 325 · see citing works
Dissecting the Functions of the Mammalian Clock Protein BMAL1 by Tissue-Specific Rescue in Mice
McDearmon, E. L., Patel, K., Ko, C. H., Walisser, J. A., Schook, A. C., Chong, J. L., Wilsbacher, L. D., Song, E. J., Hong, H., Bradfield, C. A., et al. (2006) · Science · doi:10.1126/science.1132430 · Cited by 321 · see citing works
Circadian timekeeping in BALB/c and C57BL/6 inbred mouse strains
Schwartz, W., & Zimmerman, P. (1990) · Journal of Neuroscience · doi:10.1523/jneurosci.10-11-03685.1990 · Cited by 315 · see citing works
Nuclear Entry of the Circadian Regulator mPER1 Is Controlled by Mammalian Casein Kinase I ɛ
Vielhaber, E. L., Eide, E. J., Rivers, A. M., Gao, Z.-H., & Virshup, D. M. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.13.4888-4899.2000 · Cited by 308 · see citing works
The disposal of an oral glucose load in patients with non-insulin-dependent diabetes
Ferrannini, E., Simonson, D. C., Katz, L. D., Reichard, G., Bevilacqua, S., Barrett, E. J., Olsson, M., & DeFronzo, R. A. (1988) · Metabolism · doi:10.1016/0026-0495(88)90033-9 · Cited by 305 · see citing works
The Circadian Regulatory Proteins BMAL1 and Cryptochromes Are Substrates of Casein Kinase Iε
Eide, E. J., Vielhaber, E. L., Hinz, W. A., & Virshup, D. M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111466200 · Cited by 301 · see citing works
Deletion of the Mammalian Circadian Clock Gene BMAL1/Mop3 Alters Baseline Sleep Architecture and the Response to Sleep Deprivation
Laposky, A. D., Easton, A. E., Dugovic, C., Walisser, J. A., Bradfield, C. A., & Turek, F. W. (2005) · SLEEP · doi:10.1093/sleep/28.4.395 · Cited by 297 · see citing works
SCFβ-TRCP Controls Clock-dependent Transcription via Casein Kinase 1-dependent Degradation of the Mammalian Period-1 (Per1) Proteinm
Shirogane, T., Jin, J., Cambronne, X. A., & Harper, J. W. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502862200 · Cited by 293 · see citing works
Untitled work
Zheng (1999) · doi:10.1038/22659 · Cited by 293 · see citing works
Control of Intracellular Dynamics of Mammalian Period Proteins by Casein Kinase I ε (CKIε) and CKIδ in Cultured Cells
Akashi, M., Tsuchiya, Y., Yoshino, T., & Nishida, E. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.6.1693-1703.2002 · Cited by 292 · see citing works
Scheduled exercise phase shifts the circadian clock in skeletal muscle
WOLFF, G., & ESSER, K. A. (2012) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e318255cf4c · Cited by 291 · see citing works
Self-citation
Regulation of BMAL1 Protein Stability and Circadian Function by GSK3β-Mediated Phosphorylation
Sahar, S., Zocchi, L., Kinoshita, C., Borrelli, E., & Sassone‐Corsi, P. (2009) · PLoS ONE · doi:10.1371/journal.pone.0008561 · Cited by 291 · see citing works
The dorsomedial hypothalamic nucleus as a putative food-entrainable circadian pacemaker
Mieda, M., Williams, S. C., Richardson, J. A., Tanaka, K., & Yanagisawa, M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0604189103 · Cited by 290 · see citing works
Entrainment of circadian rhythms by feeding schedules in rats with suprachiasmatic lesions
Stephan, F. K., Swann, J. M., & Sisk, C. L. (1979) · Behavioral and Neural Biology · doi:10.1016/s0163-1047(79)90332-7 · Cited by 288 · see citing works
A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3β
Hirota, T., Lewis, W. G., Liu, A. C., Lee, J. W., Schultz, P. G., & Kay, S. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811410106 · Cited by 283 · see citing works
Hepatic glucose uptake, gluconeogenesis and the regulation of glycogen synthesis.
Radziuk, J., & Pye, S. (2001) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.217 · Cited by 267 · see citing works
Differential control of peripheral circadian rhythms by suprachiasmatic-dependent neural signals
Guo, H., Brewer, J. M., Champhekar, A. S., Harris, R. B. S., & Bittman, E. L. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409734102 · Cited by 258 · see citing works
Time- and exercise-dependent gene regulation in human skeletal muscle
Zambon, A. C., McDearmon, E. L., Salomonis, N., Vranizan, K. M., Johansen, K. L., Adey, D., Takahashi, J. S., Schambelan, M., & Conklin, B. R. (2003) · Genome Biology · doi:10.1186/gb-2003-4-10-r61 · Cited by 254 · see citing works
AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism
Witczak, C. A., Sharoff, C. G., & Goodyear, L. J. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8244-6 · Cited by 250 · see citing works
Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillatorsPreprint
Saini, C., Morf, J., Stratmann, M., Gos, P., & Schibler, U. (2012) · Genes & Development · doi:10.1101/gad.183251.111 · Cited by 248 · see citing works
Development of the circadian oscillator during differentiation of mouse embryonic stem cells in vitro
Yagita, K., Horie, K., Koinuma, S., Nakamura, W., Yamanaka, I., Urasaki, A., Shigeyoshi, Y., Kawakami, K., Shimada, S., Takeda, J., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0913256107 · Cited by 241 · see citing works
The biological roles of exercise-induced cytokines: IL-6, IL-8, and IL-15
Nielsen, A. R., & Pedersen, B. K. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h07-054 · Cited by 239 · see citing works
The Implications of Multiple Circadian Clock Origins
Rosbash, M. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000062 · Cited by 239 · see citing works
Insulin resistance, the insulin resistance syndrome, and cardiovascular disease.
Gm, R. (2005) · PubMed · Cited by 238 · see citing works
BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock systemPreprint
Kondratov, R. V., Chernov, M. V., Kondratova, A. A., Gorbacheva, V., Gudkov, A. V., & Antoch, M. P. (2003) · Genes & Development · doi:10.1101/gad.1099503 · Cited by 238 · see citing works
The Calcium-Sensing Receptor: A Molecular Perspective
Magno, A. L., Ward, B. K., & Ratajczak, T. (2011) · Endocrine Reviews · doi:10.1210/er.2009-0043 · Cited by 232 · see citing works
Disrupting the circadian clock: Gene-specific effects on aging, cancer, and other phenotypes
Yu, E. A., & Weaver, D. R. (2011) · Aging · doi:10.18632/aging.100323 · Cited by 228 · see citing works
Architecture and function in the muscle sarcomere
Squire, J. M. (1997) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(97)80033-4 · Cited by 226 · see citing works
Bmal1 and β-Cell Clock Are Required for Adaptation to Circadian Disruption, and Their Loss of Function Leads to Oxidative Stress-Induced β-Cell Failure in Mice
Lee, J., Moulik, M., Fang, Z., Saha, P., Zou, F., Xu, Y., Nelson, D. L., Ma, K., Moore, D. D., & Yechoor, V. K. (2013) · Molecular and Cellular Biology · doi:10.1128/mcb.01421-12 · Cited by 224 · see citing works
Work characteristics and incidence of type 2 diabetes in women.
Kroenke, C. H., Spiegelman, D., Manson, J., Schernhammer, E. S., Colditz, G. A., & Kawachi, I. (2006) · American Journal of Epidemiology · doi:10.1093/aje/kwj355 · Cited by 220 · see citing works
Regularly scheduled voluntary exercise synchronizes the mouse circadian clock
Edgar, D. M., & Dement, W. C. (1991) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1991.261.4.r928 · Cited by 219 · see citing works
Disruption of retinoid‐related orphan receptor β changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice
André, É., Conquet, F., Steinmayr, M., Stratton, S. C., Porciatti, V., & Becker-André, M. (1998) · The EMBO Journal · doi:10.1093/emboj/17.14.3867 · Cited by 214 · see citing works
Progressive arthropathy in mice with a targeted disruption of theMop3/Bmal-1 locus
Bunger, M. K., Walisser, J. A., Sullivan, R., Manley, P. A., Moran, S. M., Kalscheur, V. L., Colman, R. J., & Bradfield, C. A. (2005) · genesis · doi:10.1002/gene.20102 · Cited by 207 · see citing works
Real-time luminescence reporting of circadian gene expression in mammals
Yamazaki, S., & Takahashi, J. S. (2005) · Methods in Enzymology · doi:10.1016/s0076-6879(05)93012-7 · Cited by 200 · see citing works
Heterogeneity of pig intestinal<scp>d</scp>-glucose transport systems
Halaihel, N., Gerbaud, D., Vasseur, M., & Alvarado, F. (1999) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1999.277.6.c1130 · Cited by 199 · see citing works
Ser-557-phosphorylated mCRY2 Is Degraded upon Synergistic Phosphorylation by Glycogen Synthase Kinase-3β
Harada, Y., Sakai, M., Kurabayashi, N., Hirota, T., & Fukada, Y. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m506225200 · Cited by 199 · see citing works
Effect of shift work on body mass index and metabolic parameters
Morikawa, Y., Nakagawa, H., Miura, K., Soyama, Y., Ishizaki, M., Kido, T., Naruse, Y., Suwazono, Y., & Nogawa, K. (2007) · Scandinavian Journal of Work, Environment & Health · doi:10.5271/sjweh.1063 · Cited by 194 · see citing works
Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice
Dubrovsky, Y. V., Samsa, W. E., & Kondratov, R. V. (2010) · Aging · doi:10.18632/aging.100241 · Cited by 184 · see citing works
The circadian cycle: daily rhythms from behaviour to genes
Merrow, M. W., Spoelstra, K., & Roenneberg, T. (2005) · EMBO Reports · doi:10.1038/sj.embor.7400541 · Cited by 183 · see citing works
Human circadian rhythms: a multioscillatory system.
Aschoff, J., & Wever, R. (1976) · PubMed · Cited by 182 · see citing works
Transcription Factors Stat3 and Stat5b Are Present in Rat Liver Nuclei Late in an Acute Phase Response and Bind Interleukin-6 Response Elements
Ripperger, J. A., Fritz, S., Richter, K., Hocke, G. M., Lottspeich, F., & Fey, G. H. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.50.29998 · Cited by 173 · see citing works
SPECTRAL RESOLUTION OF LOW-FREQUENCY, SMALL-AMPLITUDE RHYTHMS IN EXCRETED 17-KETOSTEROIDS; PROBABLE ANDROGEN-INDUCED CIRCASEPTAN DESYNCHRONIZATION
Franz Halberg, A., Engeli, M., Hamburger, C., & Hillman, D. (1965) · European Journal of Endocrinology · doi:10.1530/acta.0.050s0005 · Cited by 169 · see citing works
Impact of aging on diurnal expression patterns of CLOCK and BMAL1 in the mouse brain
Wyse, C. A., & Coogan, A. N. (2010) · Brain Research · doi:10.1016/j.brainres.2010.03.113 · Cited by 167 · see citing works
Restricted feeding schedules phase shift daily rhythms of c-Fos and protein Per1 immunoreactivity in corticolimbic regions in rats
Castellanos, A., Mendoza, J., & Escobar, C. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.064 · Cited by 163 · see citing works
The Mouse Clock Mutation Behaves as an Antimorph and Maps Within the W19H Deletion, Distal of Kit
King, D. P., Vitaterna, M. H., Chang, A., Dove, W. F., Pinto, L. H., Turek, F. W., & Takahashi, J. S. (1997) · Genetics · doi:10.1093/genetics/146.3.1049 · Cited by 162 · see citing works
Circadian gene expression in mammalian fibroblasts revealed by real-time luminescence reporting: Temperature compensation and damping
Izumo, M., Johnson, C. H., & Yamazaki, S. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2536313100 · Cited by 161 · see citing works
Effects of age on the circadian system
Turek, F. W., Penev, P. D., Zhang, Y., Reeth, O. V., & Zee, P. P. (1995) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(94)00030-5 · Cited by 159 · see citing works
Invited Review: Regulation of mammalian circadian clock genes
Albrecht, U. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00759.2001 · Cited by 159 · see citing works
Development of dilated cardiomyopathy inBmal1-deficient mice
Lefta, M., Campbell, K. S., Feng, H.-Z., Jin, J.-P., & Esser, K. A. (2012) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00238.2012 · Cited by 158 · see citing works
Self-citation
Thin Filament Mutations
Tardiff, J. C. (2011) · Circulation Research · doi:10.1161/circresaha.110.224170 · Cited by 151 · see citing works
Mitogen-activated Protein Kinase Phosphorylates and Negatively Regulates Basic Helix-Loop-Helix-PAS Transcription Factor BMAL1
Sanada, K., Okano, T., & Fukada, Y. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m107850200 · Cited by 151 · see citing works
Persistence of metabolic rhythmicity during fasting and its entrainment by restricted feeding schedules in rats
Escobar, C., Díaz‐Muñoz, M., Encinas, F. L., & Aguilar‐Roblero, R. A. (1998) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1998.274.5.r1309 · Cited by 150 · see citing works
Two Decades of Circadian Time
Hastings, M. H., Maywood, E. S., & Reddy, A. B. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01715.x · Cited by 146 · see citing works
A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation
Spengler, M. L., Kuropatwinski, K. K., Schumer, M. E., & Antoch, M. P. (2009) · Cell Cycle · doi:10.4161/cc.8.24.10273 · Cited by 145 · see citing works
Activity rhythms in the circadian domain appear in suprachiasmatic nuclei lesioned rats given methamphetamine
Honma, K., Honma, S., & Hiroshige, T. (1987) · Physiology & Behavior · doi:10.1016/0031-9384(87)90281-2 · Cited by 142 · see citing works
Anticipatory changes in liver metabolism and entrainment of insulin, glucagon, and corticosterone in food-restricted rats
Díaz‐Muñoz, M., Martínez, O. V., Aguilar‐Roblero, R. A., & Escobar, C. (2000) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2000.279.6.r2048 · Cited by 142 · see citing works
Entrainment of the master circadian clock by scheduled feeding
Castillo, M. R., Hochstetler, K. J., Tavernier, R. J., Greene, D. M., & Bult‐Ito, A. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00247.2004 · Cited by 141 · see citing works
Metabolic homeostasis in mice with disruptedClockgene expression in peripheral tissues
Kennaway, D. J., Owens, J. A., Voultsios, A., Boden, M. J., & Varcoe, T. J. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00018.2007 · Cited by 140 · see citing works
Circadian rhythm alteration of skin temperature in breast cancer.
Gautherie, M., & Gros, C. (1977) · PubMed · Cited by 133 · see citing works
Skeletal muscle adaptation to fatty acid depends on coordinated actions of the PPARs and PGC1α: implications for metabolic disease
Muoio, D. M., & Koves, T. R. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h07-083 · Cited by 129 · see citing works
Circadian Regulation of Diverse Gene Products Revealed by mRNA Expression Profiling of Synchronized Fibroblasts
Grundschober, C., Delaunay, F., Pühlhofer, A., Triqueneaux, G., Laudet, V., Bartfai, T., & Nef, P. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m107499200 · Cited by 127 · see citing works
Effects of restricted daily feeding on freerunning circadian rhythms in rats
Honma, K., von Goetz, C., & Aschoff, J. (1983) · Physiology & Behavior · doi:10.1016/0031-9384(83)90256-1 · Cited by 124 · see citing works
PHASE RELATIONS OF 24-HOUR PERIODICITIES IN BLOOD CORTICOSTERONE, MITOSES IN CORTICAL ADRENAL PARENCHYMA, AND TOTAL BODY ACTIVITY1,2
Franz Halberg, A., Peterson, R. E., & SILBER, R. H. (1959) · Endocrinology · doi:10.1210/endo-64-2-222 · Cited by 124 · see citing works
24-Hour rhythm in susceptibility of C mice to a toxic dose of ethanol
Haus, E. L., & Franz Halberg, A. (1959) · Journal of Applied Physiology · doi:10.1152/jappl.1959.14.6.878 · Cited by 123 · see citing works
Methamphetamine‐induced, suprachiasmatic nucleus‐independent circadian rhythms of activity and mPer gene expression in the striatum of the mouse
Iijima, M., Nikaido, T., Akiyama, M., Moriya, T., & Shibata, S. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02140.x · Cited by 122 · see citing works
Decreased thin filament density and length in human atrophic soleus muscle fibers after spaceflight
Riley, D. A., Bain, J. L. W., Thompson, J. L., Fitts, R. H., Widrick, J. J., Trappe, S. W., Trappe, T. A., & Costill, D. L. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.88.2.567 · Cited by 119 · see citing works
Effects of Daily Schedules of Forced Activity on Free-Running Rhythms in the Rat
Mistlberger, R. E. (1991) · Journal of Biological Rhythms · doi:10.1177/074873049100600108 · Cited by 117 · see citing works
Normal mammalian skeletal muscle and its phenotypic plasticity
Hoppeler, H. H., & Flück, M. (2002) · Journal of Experimental Biology · doi:10.1242/jeb.205.15.2143 · Cited by 108 · see citing works
Brain and Muscle Arnt-like 1 is a Key Regulator of Myogenesis
Chatterjee, S., Nam, D., Guo, B., Kim, J. M., Winnier, G. E., Lee, J., Berdeaux, R., Yechoor, V. K., & Ma, K. (2013) · Journal of Cell Science · doi:10.1242/jcs.120519 · Cited by 104 · see citing works
Aging alters the circadian rhythm of glucose utilization in the suprachiasmatic nucleus.
Wise, P. M., COHEN, I. R., Weiland, N. G., & London, E. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.14.5305 · Cited by 103 · see citing works
Molecular mechanisms of the circadian clockwork in mammals
Robinson, I., & Reddy, A. B. (2014) · FEBS Letters · doi:10.1016/j.febslet.2014.06.005 · Cited by 100 · see citing works
E3 ligases Arf-bp1 and Pam mediate lithium-stimulated degradation of the circadian heme receptor Rev-erbα
Yin, L., Joshi, S., Wu, N., Tong, X., & Lazar, M. A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000438107 · Cited by 100 · see citing works
Regulation of Circadian Gene Expression in Liver by Systemic Signals and Hepatocyte OscillatorsPreprint
Kornmann, B., Schaad, O., Reinke, H., Saini, C., & Schibler, U. (2007) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2007.72.041 · Cited by 99 · see citing works
Time-restricted feeding entrains daily rhythms of energy metabolism in mice
Satoh, Y., Kawai, H. F., Kudo, N., Kawashima, Y., & Mitsumoto, A. (2005) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00775.2005 · Cited by 99 · see citing works
Circadian rhythmicity after neural transplant to hamster third ventricle: specificity of suprachiasmatic nuclei
DeCoursey, P. J., & Buggy, J. (1989) · Brain Research · doi:10.1016/0006-8993(89)90322-3 · Cited by 93 · see citing works
Circadian rhythms in the rat: Constant darkness, entrainment to T cycles and to skeleton photoperiods
Stephan, F. K. (1983) · Physiology & Behavior · doi:10.1016/0031-9384(83)90152-x · Cited by 91 · see citing works
“Feeding time” for the brain: A matter of clocks
Feillet, C. A., Albrecht, U., & Challet, É. (2006) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2007.05.002 · Cited by 90 · see citing works
When contractile proteins go bad: the sarcomere and skeletal muscle disease
Laing, N. G., & Nowak, K. J. (2005) · BioEssays · doi:10.1002/bies.20269 · Cited by 88 · see citing works
Features of Circadian Rhythms Relevant for the Design of Shift Schedules
Aschoff, J. (1978) · Ergonomics · doi:10.1080/00140137808931777 · Cited by 88 · see citing works
Nonphotic Phase Shifting in Hamster Clock Mutants
Mrosovsky, N., Salmon, P. A., Menaker, M., & Ralph, M. R. (1992) · Journal of Biological Rhythms · doi:10.1177/074873049200700104 · Cited by 85 · see citing works
CREB Influences Timing and Entrainment of the SCN Circadian Clock
Lee, B., Li, A., Hansen, K. F., Cao, R., Yoon, J. H., & Obrietan, K. H. (2010) · Journal of Biological Rhythms · doi:10.1177/0748730410381229 · Cited by 84 · see citing works
Scheduled exposures to a novel environment with a running‐wheel differentially accelerate re‐entrainment of mice peripheral clocks to new light–dark cycles
Yamanaka, Y., Honma, S., & Honma, K.-I. (2008) · Genes to Cells · doi:10.1111/j.1365-2443.2008.01183.x · Cited by 82 · see citing works
Phase response curves to light in young and old hamsters
Rosenberg, R. S., Zee, P. C., & Turek, F. W. (1991) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1991.261.2.r491 · Cited by 82 · see citing works
[Glossary of chronobiology (author's transl)].
Franz Halberg, A., Carandente, F., Cornelissen, G., & Gs, K. (1977) · PubMed · Cited by 82 · see citing works
Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle
Vieira, E. C., Nilsson, E. C., Nerstedt, A., Ormestad, M., Long, Y. C., García-Rovés, P. M., Zierath, J. R., & Mahlapuu, M. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.90510.2008 · Cited by 80 · see citing works
The methamphetamine-sensitive circadian oscillator does not employ canonical clock genes
Mohawk, J. A., Baer, M. L., & Menaker, M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813366106 · Cited by 80 · see citing works
The 2008 Pittendrigh/Aschoff Lecture: Peripheral Phase Coordination in the Mammalian Circadian Timing System
Schibler, U. (2009) · Journal of Biological Rhythms · doi:10.1177/0748730408329383 · Cited by 79 · see citing works
Vasoactive intestinal polypeptide requires parallel changes in adenylate cyclase and phospholipase C to entrain circadian rhythms to a predictable phase
An, S., Irwin, R. P., Allen, C. N., Tsai, C. A., & Herzog, E. D. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00966.2010 · Cited by 74 · see citing works
Relationships between circadian rhythms and modulation of gene expression by glucocorticoids in skeletal muscle
Almon, R. R., Yang, E., Lai, W., Androulakis, I. P., Ghimbovschi, S. D., Hoffman, E. P., Jusko, W. J., & DuBois, D. C. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.90399.2008 · Cited by 70 · see citing works
Serine phosphorylation of mCRY1 and mCRY2 by mitogen‐activated protein kinase
Sanada, K., Harada, Y., Sakai, M., Todo, T., & Fukada, Y. (2004) · Genes to Cells · doi:10.1111/j.1356-9597.2004.00758.x · Cited by 69 · see citing works
Cachexia in chronic heart failure: Prognostic implications and novel therapeutic approaches
Akashi, Y. J., Springer, J., & Anker, S. D. (2005) · Current Heart Failure Reports · doi:10.1007/bf02696650 · Cited by 67 · see citing works
Endurance training ameliorates the metabolic and performance characteristics of circadianClockmutant mice
Pastore, S., & Hood, D. A. (2013) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01505.2012 · Cited by 66 · see citing works
Food anticipatory activity and photic entrainment in food-restricted BALB/c mice
Holmes, M. M., & Mistlberger, R. E. (2000) · Physiology & Behavior · doi:10.1016/s0031-9384(99)00231-0 · Cited by 66 · see citing works
SirT1 in muscle physiology and disease: lessons from mouse models
Vinciguerra, M., Fulco, M., Ladurner, A. G., Sartorelli, V., & Rosenthal, N. A. (2010) · Disease Models & Mechanisms · doi:10.1242/dmm.004655 · Cited by 66 · see citing works

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Pelley JW 2012 Elsevier's Integrated Review Biochemistry New York Elsevier
Poole DC 1986 Measurements of the anaerobic work capacity in a group of highly trained runners Med Sci Sports Exerc 18 703 705 3784883

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Correa-de-Araujo, R., Addison, O., Miljkovic, I., Goodpaster, B. H., Bergman, B. C., Clark, R. V., Elena, J. W., Esser, K. A., Ferrucci, L., Harris-Love, M. O., et al. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00963 · Cited by 468 · see citing works
Self-citation
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Roberts, M. D., McCarthy, J. J., Hornberger, T. A., Phillips, S. M., Mackey, A. L., Nader, G. A., Boppart, M. D., Kavazis, A. N., Reidy, P. T., Ogasawara, R., et al. (2023) · Physiological Reviews · doi:10.1152/physrev.00039.2022 · Cited by 214 · see citing works
Self-citation
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Nohara, K., Mallampalli, V. K. P. S., Nemkov, T. G., Wirianto, M., Yang, J., Ye, Y., Sun, Y., Han, L., Esser, K. A., Mileykovskaya, E., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-11926-y · Cited by 190 · see citing works
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Gerhart-Hines, Z., & Lazar, M. A. (2015) · Endocrine Reviews · doi:10.1210/er.2015-1007 · Cited by 178 · see citing works
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Self-citation
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Perrin, L., Loizides-Mangold, U., Chanon, S., Gobet, C., Hulo, N., Isenegger, L., Weger, B. D., Migliavacca, E., Charpagne, A., Betts, J. A., et al. (2018) · eLife · doi:10.7554/elife.34114 · Cited by 139 · see citing works
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Jordan, S. D., Kriebs, A., Vaughan, M. E., Duglan, D., Fan, W., Henriksson, E., Huber, A., Papp, S. J., Nguyen, M., Afetian, M. E., et al. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.06.002 · Cited by 112 · see citing works
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Perrin, L., Loizides‐Mangold, U., Skarupelova, S., Pulimeno, P., Chanon, S., Robert, M., Bouzakri, K., Modoux, C., Roux‐Lombard, P., Vidal, H., et al. (2015) · Molecular Metabolism · doi:10.1016/j.molmet.2015.07.009 · Cited by 105 · see citing works
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Stacchiotti, A., Favero, G., & Rodella, L. F. (2020) · Cells · doi:10.3390/cells9020288 · Cited by 115 · see citing works
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Altered feeding differentially regulates circadian rhythms and energy metabolism in liver and muscle of rats
Reznick, J., Preston, E., Wilks, D. L., Beale, S. M., Turner, N., & Cooney, G. J. (2013) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2012.08.010 · Cited by 86 · see citing works
Human adipose tissue expresses intrinsic circadian rhythm in insulin sensitivity
Carrasco‐Benso, M. P., Rivero‐Gutiérrez, B., Lόpez-Mínguez, J., Anzola, A., Dı́ez-Noguera, A., Madrid, J. A., Luján, J., Martínez‐Augustin, O., Scheer, F. A. J. L., & Garaulet, M. (2016) · The FASEB Journal · doi:10.1096/fj.201600269rr · Cited by 80 · see citing works
Circadian regulation of metabolic homeostasis: causes and consequences
Young, M. E., & McGinnis, G. R. (2016) · Nature and Science of Sleep · doi:10.2147/nss.s78946 · Cited by 80 · see citing works
Emerging relevance of circadian rhythms in headaches and neuropathic pain
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Oh, H. Y. P., Visvalingam, V., & Wahli, W. (2019) · The FASEB Journal · doi:10.1096/fj.201802681rr · Cited by 78 · see citing works
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Zhang, S., Dai, M., Wang, X., Jiang, S.-H., Hu, L.-P., Zhang, X., & Zhang, Z. (2020) · Cellular Signalling · doi:10.1016/j.cellsig.2019.109433 · Cited by 76 · see citing works
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Lowe, M. G., Lage, J., Paatela, E., Munson, D., Hostager, R., Yuan, C., Katoku-Kikyo, N., Ruíz-Estévez, M., Asakura, Y., Staats, J., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.01.077 · Cited by 69 · see citing works
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Timmons, G. A., Carroll, R. G., O’Siorain, J. R., Cervantes‐Silva, M. P., Fagan, L. E., Cox, S. L., Pålsson‐McDermott, E. M., Finlay, D. K., Vincent, E. E., Jones, N., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.700431 · Cited by 72 · see citing works
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Small, L., Altıntaş, A., Laker, R. C., Ehrlich, A. M., Pattamaprapanont, P., Villarroel, J., Pillon, N. J., Zierath, J. R., & Barrès, R. (2020) · The Journal of Physiology · doi:10.1113/jp280428 · Cited by 56 · see citing works
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Synchronized human skeletal myotubes of lean, obese and type 2 diabetic patients maintain circadian oscillation of clock genes
Hansen, J., Timmers, S., Moonen‐Kornips, E., Duez, H., Staels, B., Hesselink, M. K. C., & Schrauwen, P. (2016) · Scientific Reports · doi:10.1038/srep35047 · Cited by 54 · see citing works
The myonuclear DNA methylome in response to an acute hypertrophic stimulus
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Circadian disruption by shifting the light‐dark cycle negatively affects bone health in mice
Schilperoort, M., Bravenboer, N., Lim, J., Mletzko, K., Busse, B., van Ruijven, L. J., Kroon, J., Rensen, P. C. N., Kooijman, S., & Winter, E. M. (2019) · The FASEB Journal · doi:10.1096/fj.201901929r · Cited by 51 · see citing works
Ambient fine particulate matter disrupts hepatic circadian oscillation and lipid metabolism in a mouse model
Li, R., Wang, Y., Chen, R., Gu, W., Zhang, L., Gu, J., Wang, Z., Liu, Y., Sun, Q., Zhang, K., et al. (2020) · Environmental Pollution · doi:10.1016/j.envpol.2020.114179 · Cited by 49 · see citing works
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Choi, Y. I., Park, D. K., Chung, J., Kim, K. O., Kwon, K. A., & Kim, Y. J. (2019) · Scientific Reports · doi:10.1038/s41598-019-48161-w · Cited by 47 · see citing works
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Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across Drosophila populationsPreprint
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Saner, N. J., Bishop, D. J., & Bartlett, J. D. (2018) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2017.01.001 · Cited by 41 · see citing works
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Méndez, I. G., Martínez, O. V., Hernández-Muñoz, R. E., Valente‐Godínez, H., & Díaz‐Muñoz, M. (2015) · Biochimie · doi:10.1016/j.biochi.2015.04.014 · Cited by 41 · see citing works
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When to eat? The influence of circadian rhythms on metabolic health: are animal studies providing the evidence?
Morán‐Ramos, S., Báez‐Ruíz, A., Buijs, R. M., & Escobar, C. (2016) · Nutrition Research Reviews · doi:10.1017/s095442241600010x · Cited by 37 · see citing works
MECHANISMS IN ENDOCRINOLOGY: A sense of time of the glucocorticoid circadian clock: from the ontogeny to the diagnosis of Cushing’s syndrome
Moreira, A. C., Antonini, S. R. R., & de Castro, M. (2018) · European Journal of Endocrinology · doi:10.1530/eje-18-0102 · Cited by 37 · see citing works
Time‐restricted feeding during the inactive phase abolishes the daily rhythm in mitochondrial respiration in rat skeletal muscle
de Goede, P., Wüst, R. C. I., Schomakers, B. V., Denis, S. W., Vaz, F. M., Pras‐Raves, M. L., van Weeghel, M., Yi, C., Kalsbeek, A., & Houtkooper, R. H. (2022) · The FASEB Journal · doi:10.1096/fj.202100707r · Cited by 36 · see citing works
The association between sleep parameters and sarcopenia in Japanese community-dwelling older adults
Shibuki, T., Iida, M., Harada, S., Kato, S., Kuwabara, K., Hirata, A., Sata, M., Matsumoto, M., Osawa, Y., Okamura, T., et al. (2023) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2023.104948 · Cited by 35 · see citing works
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Wirianto, M., Yang, J., Kim, E., Gao, S., Paudel, K. R., Choi, J. M., Choe, J., Gloston, G. F., Ademoji, P., Parakramaweera, R., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108140 · Cited by 35 · see citing works
Self-citation
Unraveling On-demand Strain-Stiffening in Nanofibrous Peptide–Polymer Conjugates to Mimic Contractility in Actinomyosin Networks
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Exercise Training Impacts Skeletal Muscle Clock Machinery in Prediabetes
Erickson, M. L., ZHANG, H., Mey, J. T., & Kirwan, J. P. (2020) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002368 · Cited by 31 · see citing works
Irisin/BDNF signaling in the muscle-brain axis and circadian system: A review
Inyushkin, A. N., Полетаев, В., Михайловна, И. Е., Сергеевич, К. И., & Inyushkin, A. A. (2023) · Journal of Biomedical Research · doi:10.7555/jbr.37.20230133 · Cited by 30 · see citing works
A prospective study on the association of sleep duration with grip strength among middle-aged and older Chinese
Wang, T. Y., Wu, Y., Wang, T., Li, Y., & Zhang, D. (2018) · Experimental Gerontology · doi:10.1016/j.exger.2018.01.009 · Cited by 30 · see citing works
Impact of short- and long-term electrically induced muscle exercise on gene signaling pathways, gene expression, and PGC1a methylation in men with spinal cord injury
Petrie, M. A., Sharma, A., Taylor, E. B., Suneja, M., & Shields, R. K. (2019) · Physiological Genomics · doi:10.1152/physiolgenomics.00064.2019 · Cited by 28 · see citing works
Cortisol Circadian Rhythm and Insulin Resistance in Muscle: Effect of Dosing and Timing of Hydrocortisone Exposure on Insulin Sensitivity in Synchronized Muscle Cells
Negri, M., Pivonello, C., Simeoli, C., Gennaro, G. D., Venneri, M. A., Sciarra, F., Ferrigno, R., de Angelis, C., Sbardella, E., Martino, M. C. D., et al. (2020) · Neuroendocrinology · doi:10.1159/000512685 · Cited by 27 · see citing works
Application of nutrigenomics in small ruminants: Lactation, growth, and beyond
Osorio, J. S., Vailati-Riboni, M., Palladino, A., Luo, J., & Loor, J. J. (2017) · Small Ruminant Research · doi:10.1016/j.smallrumres.2017.06.021 · Cited by 28 · see citing works
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Malhan, D., Yalçın, M., Schoenrock, B., Blottner, D., & Relógio, A. (2023) · npj Microgravity · doi:10.1038/s41526-023-00273-4 · Cited by 27 · see citing works
The clock regulator Bmal1 protects against muscular dystrophy
Gao, H., Xiong, X., Lin, Y., Chatterjee, S., & Ma, K. (2020) · Experimental Cell Research · doi:10.1016/j.yexcr.2020.112348 · Cited by 26 · see citing works
Roles of peripheral clocks: lessons from the fly
Yildirim, E., Curtis, R., & Hwangbo, D. (2021) · FEBS Letters · doi:10.1002/1873-3468.14251 · Cited by 25 · see citing works
Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles
Chadwick, J. A., Bhattacharya, S., Lowe, J., Weisleder, N. L., & Rafael‐Fortney, J. A. (2016) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00269.2016 · Cited by 24 · see citing works
RNA-Seq transcriptome analysis of breast muscle in Pekin ducks supplemented with the dietary probiotic Clostridium butyricum
Liu, Y., Jia, Y., Liu, C., Ding, L., & Xia, Z. (2018) · BMC Genomics · doi:10.1186/s12864-018-5261-1 · Cited by 24 · see citing works
Muscle weakness: Understanding the principles of myopathy and neuropathy in the critically ill patient and the management options
Martínez‐García, M. Á., González, J. C. M., y Mateos, A. G.-D.-L., & Teijeira, S. (2019) · Clinical Nutrition · doi:10.1016/j.clnu.2019.05.027 · Cited by 26 · see citing works
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Nohara, K., Kim, E., Wirianto, M., Mileykovskaya, E., Dowhan, W., Chen, Z., & Yoo, S. H. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/5304768 · Cited by 24 · see citing works
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Gao, C. A., & Knauert, M. P. (2019) · Seminars in Respiratory and Critical Care Medicine · doi:10.1055/s-0039-1698394 · Cited by 24 · see citing works
BMAL1 controls glucose uptake through paired-homeodomain transcription factor 4 in differentiated Caco-2 cells
Sussman, W., Stevenson, M., Mowdawalla, C., Mota, S., Ragolia, L., & Pan, X. (2019) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00058.2019 · Cited by 23 · see citing works
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Counts, B. R., Hardee, J. P., Fix, D. K., VanderVeen, B. N., Montalvo, R. N., & Carson, J. A. (2019) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002166 · Cited by 23 · see citing works
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Malila, Y., Uengwetwanit, T., Arayamethakorn, S., Srimarut, Y., Thanatsang, K. V., Soglia, F., Strasburg, G. M., Rungrassamee, W., & Visessanguan, W. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00580 · Cited by 22 · see citing works
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Yang, L., Lang, H., Zhou, M., Huang, L., Hui, S., Wang, X., Chen, K., & Mi, M. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900991 · Cited by 20 · see citing works
Circadian secretion rhythm of GLP-1 and its influencing factors
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Franza, L., & Cianci, R. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18126330 · Cited by 20 · see citing works
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Priyadarsini, N., Nanda, P., Devi, S., & Mohapatra, S. (2022) · Current Aging Science · doi:10.2174/1874609815666220304194539 · Cited by 19 · see citing works
The association between chrononutrition behaviors and muscle health among older adults: The study of muscle, mobility and aging
Mao, Z., Cawthon, P. M., Kritchevsky, S. B., Toledo, F. G. S., Esser, K. A., Erickson, M. L., Newman, A. B., & Farsijani, S. (2023) · Aging Cell · doi:10.1111/acel.14059 · Cited by 21 · see citing works
Self-citation
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Steidle‐Kloc, E., Schönfelder, M., Müller, E., Sixt, S., Schuler, G. C., Patsch, W., & Niebauer, J. (2016) · European Journal of Preventive Cardiology · doi:10.1177/2047487316639682 · Cited by 18 · see citing works
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Aoyama, S., Nakahata, Y., & Shinohara, K. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.659883 · Cited by 20 · see citing works
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Dent, J. R., Stocks, B., Campelj, D. G., & Philp, A. (2022) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2022.03.022 · Cited by 18 · see citing works
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Tiwari, A., Rathor, P., Trivedi, P. K., & Ch, R. (2023) · Biology · doi:10.3390/biology12020301 · Cited by 17 · see citing works
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Sutton, E. R., & Pekovic‐Vaughan, V. (2025) · Antioxidants · doi:10.3390/antiox14091132 · Cited by 17 · see citing works
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Bilu, C., Einat, H., Zimmet, P., Vishnevskia‐Dai, V., Schwartz, W. J., & Kronfeld‐Schor, N. (2022) · Scientific Reports · doi:10.1038/s41598-022-06408-z · Cited by 17 · see citing works
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CAMERA, D. M. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00569 · Cited by 17 · see citing works
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Keshvari, M., Nejadtaghi, M., Hosseini-Beheshti, F., Rastqar, A., & Patel, N. (2019) · Chronobiology International · doi:10.1080/07420528.2019.1681440 · Cited by 17 · see citing works
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Adamovich, Y., Ezagouri, S., Dandavate, V., & Asher, G. (2021) · STAR Protocols · doi:10.1016/j.xpro.2021.100331 · Cited by 17 · see citing works
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Liu, K., Meng, T., Chen, Q., Hou, G., Wang, X., Hu, S.-H., Gu, X., Li, H., Li, Y., Xiong, C., et al. (2022) · Human Reproduction · doi:10.1093/humrep/deac135 · Cited by 16 · see citing works
Longitudinal association of sleep duration with possible sarcopenia: evidence from CHARLS
Lv, X., Peng, W., Jia, B., Lin, P., & Yang, Z. (2024) · BMJ Open · doi:10.1136/bmjopen-2023-079237 · Cited by 17 · see citing works
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Petrie, M. A., Taylor, E. B., Suneja, M., & Shields, R. K. (2021) · Physical Therapy · doi:10.1093/ptj/pzab243 · Cited by 16 · see citing works
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Devore, E. E., Harrison, S. L., Stone, K. L., Holton, K. F., Barrett-Connor, E. L., Ancoli‐Israel, S., Yaffe, K. S., Ensrud, K. E., Cawthon, P. M., Redline, S. S., et al. (2016) · Sleep Medicine · doi:10.1016/j.sleep.2016.07.006 · Cited by 16 · see citing works
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Liu, J., Xiao, F., Choubey, A., Kumar, S. U., Wang, Y., Hong, S., Yang, T., Otlu, H. G., Oturmaz, E. S., Loro, E., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60520-y · Cited by 19 · see citing works
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Su, Z., & Xiang, L. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1633835 · Cited by 15 · see citing works
Retracted
Effect of changes in sleeping behavior on skeletal muscle and fat mass: a retrospective cohort study
Song, J., Park, S. J., Choi, S., Han, M., Oh, Y. H., Oh, Y. H., & Park, S. M. (2023) · BMC Public Health · doi:10.1186/s12889-023-16765-7 · Cited by 15 · see citing works
A procession of metabolic alterations accompanying muscle senescence in Manduca sexta
Wone, B. W. M., Kinchen, J. M., Kaup, E. R., & Wone, B. (2018) · Scientific Reports · doi:10.1038/s41598-018-19630-5 · Cited by 15 · see citing works
Blind Spot for Sedentarism: Redefining the Diseasome of Physical Inactivity in View of Circadian System and the Irisin/BDNF Axis
Zsuga, J., Móré, C. E., Erdei, T., Papp, C., Harsányi, S., & Gesztelyi, R. (2018) · Frontiers in Neurology · doi:10.3389/fneur.2018.00818 · Cited by 15 · see citing works
Metabolic state switches between morning and evening in association with circadian clock in people without diabetes
Fujimoto, R., Ohta, Y., Masuda, K., Taguchi, A., Akiyama, M., Yamamoto, K., Nakabayashi, H., Nagao, Y., Matsumura, T., Hiroshige, S., et al. (2022) · Journal of Diabetes Investigation · doi:10.1111/jdi.13810 · Cited by 14 · see citing works
Mechanosensors control skeletal muscle mass, molecular clocks, and metabolism
Vanmunster, M., Rojo‐García, A. V., Pacolet, A., Dalle, S., Koppo, K., Jonkers, I., Lories, R. J. U., & Suhr, F. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04346-7 · Cited by 14 · see citing works
Melatonin and Exercise Restore Myogenesis and Mitochondrial Dynamics Deficits Associated With Sarcopenia in iMS‐ Bmal1 −/− Mice
Ramírez‐Casas, Y., Fernández‐Martínez, J., Martín‐Estebané, M., Aranda‐Martínez, P., López‐Rodríguez, A., Esquivel‐Ruiz, S., Yang, Y., Escames, G., & Acuña-Castroviejo, D. (2025) · Journal of Pineal Research · doi:10.1111/jpi.70049 · Cited by 14 · see citing works
Chrono-Aerobic Exercise Optimizes Metabolic State in DB/DB Mice through CLOCK–Mitophagy–Apoptosis
Zhang, Z., Li, X., Zhang, J., Du, J., Zhang, Q., Ge, Z., & Ding, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23169308 · Cited by 14 · see citing works
Interrelated but Not Time-Aligned Response in Myogenic Regulatory Factors Demethylation and mRNA Expression after Divergent Exercise Bouts
Telles, G. D., Libardi, C. A., Conceição, M. S., VECHIN, F. C., Lixandrão, M. E., Mangone, F. R., Pavanelli, A. C., Nagai, M. A., CAMERA, D. M., Hawley, J. A., et al. (2022) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000003049 · Cited by 14 · see citing works
Association between Sleep Duration and Grip Strength in U.S. Older Adults: An NHANES Analysis (2011–2014)
Liu, J., Zhang, T., Luo, J., Chen, S., & Zhang, D. (2023) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph20043416 · Cited by 12 · see citing works
Histone deacetylase functions and therapeutic implications for adult skeletal muscle metabolism
Molinari, S., Imbriano, C., Moresi, V., Renzini, A., Belluti, S., Lozanoska‐Ochser, B., Gigli, G., & Cedola, A. (2023) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2023.1130183 · Cited by 12 · see citing works
Clock genes regulate skeletal muscle energy metabolism through NAMPT/NAD + /SIRT1 following heavy-load exercise
Xia, Y., Yao, B., Fu, Z., Li, L., Jin, S., Qu, B., Huang, Y., & Ding, H. (2023) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00261.2022 · Cited by 12 · see citing works
The Long Haul: Migratory Flight Preparation and Performance in Songbirds
Dick, M. F. (2017) · Scholarship@Western (Western University) · Cited by 12 · see citing works

Skeletal muscle functions around the clock
Mayeuf-Louchart, A., Staels, B., & Duez, H. (2015) · Diabetes Obesity and Metabolism · doi:10.1111/dom.12517 · Cited by 57 · see citing works
The Role of the Molecular Clock in Promoting Skeletal Muscle Growth and Protecting against Sarcopenia
Vitale, J. A., Bonato, M., Torre, A. L., & Banfi, G. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20174318 · Cited by 51 · see citing works
Working around the clock: circadian rhythms and skeletal muscle
Zhang, X., Dube, T. J., & Esser, K. A. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00725.2009 · Cited by 64 · see citing works
Self-citation
Skeletal muscle clock and metabolism
Li, Y., & Chen, W. (2020) · Biological Rhythm Research · doi:10.1080/09291016.2020.1816037 · Cited by 3 · see citing works
Running skeletal muscle clocks on time— the determining factors
Vaca-Dempere, M., Kumar, A., Sica, V., & Muñoz‐Cánoves, P. (2022) · Experimental Cell Research · doi:10.1016/j.yexcr.2021.112989 · Cited by 7 · see citing works

Authors: Harfmann, B. D., Schroder, E. A., & Esser, K. A.
Affiliations: University of Kentucky (US)
Corresponding author: Esser, Karyn A.
ORCID: Harfmann, Brianna D.
Schroder, Elizabeth A.
Esser, Karyn A.
Venue: Journal of Biological Rhythms
Publisher: SAGE Publications
Published: 2014-12-15
Volume: 30
Issue: 2
Pages: 84-94
ISSN: 0748-7304 (ISSN-L)
1552-4531
DOI: 10.1177/0748730414561638
PMC: PMC4470613
OpenAlex: W2166609167
Cited by: 211
References: 234
Citations by year: 2026: 21 · 2025: 18 · 2024: 19 · 2023: 20 · 2022: 26 · 2021: 17 · 2020: 29 · 2019: 15 · 2018: 11 · 2017: 14 · 2016: 13 · 2015: 7 · 2012: 1
FWCI: 1.28
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)
Locations: Journal of Biological Rhythms (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: University of Kentucky
National Institutes of Health
National Institute of Environmental Health Sciences (RC1ES018636)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR066082, AR066082, R01AR055246)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
Keywords: circadian rhythm, molecular clock, skeletal muscle, clock genes, Bmal1, clocks, suprachiasmatic nucleus, circadian entrainment, meal timing, circadian gene expression, muscle fiber type shift, mitochondrial respiration, glucose tolerance, insulin sensitivity, muscle metabolism
MeSH terms: Animals, Circadian Rhythm, Gene Expression Regulation, Humans, Mutation, Suprachiasmatic Nucleus, Muscle, Skeletal, Mice, CLOCK Proteins, Circadian Clocks

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Circadian Rhythms, the Molecular Clock, and Skeletal Muscle

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