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Cooccurrence and bidirectional prediction of sleep disturbances and depression in older adults: Meta-analysis and systematic review

Bao, Yan-Ping, Han, Ying, Ma, Jun, Wang, Ru-Jia, Shi, Le, Wang, Tong-Yu, He, Jia, Yue, Jing-Li, Shi, Jie, Tang, Xiang-Dong, Lu, Lin·2017·Neuroscience & Biobehavioral Reviews

DOI 10.1016/j.neubiorev.2017.01.032

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Abstract

The present study pooled the prevalence of sleep disturbances and depression in community-dwelling older adults (mean age≥60years) and quantified the strength of evidence of the relationship between these two problems. From 23 cross-sectional studies and five sets of baseline data, a high pooled prevalence of sleep disturbances (30.5%), depressive symptoms (18.1%) and coexisting disorders (10.6%) were found. In the 23 cohort studies, self-reported sleep disturbances increased the risk of the onset of depression (relative risk [RR]=1.92). Persistent sleep disturbances increased the risk of the development (RR=3.90), recurrence (RR=7.70), and worsening (RR=1.46) of depression in older adults. Little support was found for a predictive role for objective sleep characteristics in the development of depression. Older adults with depression had a higher risk of developing (RR=1.72) and worsening (RR=1.73) symptoms of sleep disturbances. This review emphasizes the importance of timely interventions in incipient sleep disturbances and depression among older adults, preventing the development of more serious comorbidities.

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Self-citation
Mapping risk factors for depression across the lifespan: An umbrella review of evidence from meta-analyses and Mendelian randomization studies
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Authors: Bao, Y.-P., Han, Y., Ma, J., Wang, R.-J., Shi, L., Wang, T.-Y., He, J., Yue, J.-L., Shi, J., Tang, X.-D., & Lu, L.
Affiliations: Peking University (CN)
ORCID: Han, Ying
Ma, Jun
Shi, Le
Yue, Jing-Li
Shi, Jie
Venue: Neuroscience & Biobehavioral Reviews
Publisher: Elsevier BV
Published: 2017-04
Volume: 75
Pages: 257-273
ISSN: 0149-7634 (ISSN-L)
DOI: 10.1016/j.neubiorev.2017.01.032
OpenAlex: W2583719463
Cited by: 275
References: 123
Citations by year: 2026: 30 · 2025: 36 · 2024: 34 · 2023: 36 · 2022: 37 · 2021: 35 · 2020: 27 · 2019: 19 · 2018: 17 · 2017: 4
FWCI: 2.94
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience & Biobehavioral Reviews (publishedVersion)
PubMed (publishedVersion)
Funders: National Basic Research Program of China (2015CB856400, 2015CB553503)
National Natural Science Foundation of China (81521063)
Beijing Municipal Science and Technology Commission (Z151100003915121)
Thirteenth Five-Year Program of the Chinese Ministry of Science and Technology (2016YFC0800907)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
Keywords: sleep disorders, depression, older adults, bidirectional prediction, comorbidities, prevalence, depression recurrence, community-dwelling older adults
MeSH terms: Cross-Sectional Studies, Depression, Depressive Disorder, Humans, Middle Aged, Sleep Wake Disorders, Comorbidity

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Cooccurrence and bidirectional prediction of sleep disturbances and depression in older adults: Meta-analysis and systematic review

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