Cited by 451Pain Mechanisms and TreatmentsSex and Gender in HealthcareMusculoskeletal pain and rehabilitation

The DOI matches its Crossref record; 207 of the 210 references it cites were found in a registry or an index.

A systematic literature review of 10 years of research on sex/gender and pain perception – Part 2: Do biopsychosocial factors alter pain sensitivity differently in women and men?

Racine, Mélanie, Tousignant-Laflamme, Yannick, Kloda, Lorie A., Dion, Dominique, Dupuis, Gilles, Choinière, Manon·2012·Pain

DOI 10.1016/j.pain.2011.11.026

Open this paper in CoChat — free account

Abstract

This systematic review summarizes the results of 10 years of laboratory research on pain and sex/gender. An electronic search strategy was designed by a medical librarian to access multiple databases. A total of 172 articles published between 1998 and 2008 were retrieved, analyzed, and synthesized. The second set of results presented in this review (129 articles) examined various biopsychosocial factors that may contribute to differences in pain sensitivity between healthy women and men. The results revealed that the involvement of hormonal and physiological factors is either inconsistent or absent. Some studies suggest that temporal summation, allodynia, and secondary hyperalgesia may be more pronounced in women than in men. The evidence to support less efficient endogenous pain inhibitory systems in women is mixed and does not necessarily apply to all pain modalities. With regard to psychological factors, depression may not mediate sex differences in pain perception, while the role of anxiety is ambiguous. Cognitive and social factors appear to partly explain some sex-related differences. Finally, past individual history may be influential in female pain responses. However, these conclusions must be treated with much circumspection for various methodological reasons. Furthermore, some factors/mechanisms remain understudied in the field. There is also a need to assess and improve the ecological validity of findings from laboratory studies on healthy subjects, and perhaps a change of paradigm needs to be considered at this point in time to better understand the factors that influence the experience of women and men who suffer from acute or chronic pain.

Integrity signals

Registry

Crossref · 10.1016/j.pain.2011.11.026

Cites

207 of 207 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-efficacy: The exercise of control
Bandura, A., Freeman, W. H., & Lightsey, R. (1999) · Journal of Cognitive Psychotherapy · doi:10.1891/0889-8391.13.2.158 · Cited by 46,835
A Global Measure of Perceived Stress
Cohen, S., Kamarck, T., & Mermelstein, R. (1983) · Journal of Health and Social Behavior · doi:10.2307/2136404 · Cited by 32,807
Untitled work
(1970) · Cited by 24,983
The measurement of psychological androgyny
Bem, S. L. (1974) · Journal of Consulting and Clinical Psychology · doi:10.1037/h0036215 · Cited by 8,522
The Pain Catastrophizing Scale: Development and validation.
Sullivan, M. J. L., Bishop, S. R., & Pivik, J. (1995) · Psychological Assessment · doi:10.1037//1040-3590.7.4.524 · Cited by 8,227
Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment
Breivik, H., Collett, B., Ventafridda, V., Cohen, R., & Gallacher, D. (2006) · European Journal of Pain · doi:10.1016/j.ejpain.2005.06.009 · Cited by 5,486
Anxiety, sensitivity, anxiety frequency, and the prediction of fearfulness
Reiss, S., Peterson, R. A., Gursky, D. M., & McNally, R. J. (1986) · Behaviour Research and Therapy · doi:10.1016/0005-7967(86)90143-9 · Cited by 3,169
Sex, gender, and pain: a review of recent clinical and experimental findings
Fillingim, R. B., King, C. D., Ribeiro-Dasilva, M. C., Rahim-Williams, B., & Riley, J. L. (2009) · The Journal of Pain · doi:10.1016/j.jpain.2008.12.001 · Cited by 2,766
The use of coping strategies in chronic low back pain patients: Relationship to patient characteristics and current adjustment
Rosenstiel, A. K., & Keefe, F. J. (1983) · Pain · doi:10.1016/0304-3959(83)90125-2 · Cited by 2,314
Systematic Reviews in Health Care : Meta-Analysis in Context
Egger, M., Smith, G. D., & Altman, D. G. (2000) · Cited by 2,312
Gender variations in clinical pain experience
Unruh, A. M. (1996) · Pain · doi:10.1016/0304-3959(95)00214-6 · Cited by 1,550
Diffuse noxious inhibitory controls (DNIC). I. Effects on dorsal horn convergent neurones in the rat
Bars, D. L., Dickenson, A. H., & Besson, J. (1979) · Pain · doi:10.1016/0304-3959(79)90049-6 · Cited by 1,370
Sex differences in pain
Berkley, K. J. (1997) · Behavioral and Brain Sciences · doi:10.1017/s0140525x97221485 · Cited by 1,125
Chronic pain in Australia: a prevalence study.
Blyth, F. M., March, L. M., Brnabic, A. J. M., Jorm, L. R., Williamson, M., & Cousins, M. J. (2001) · Pain · doi:10.1016/s0304-3959(00)00355-9 · Cited by 1,096
Sex differences in the perception of noxious experimental stimuli: a meta-analysis
Riley, J. L., Robinson, M. E., Wise, E. A., Myers, C. D., & Fillingim, R. B. (1998) · Pain · doi:10.1016/s0304-3959(97)00199-1 · Cited by 1,085
Studying sex and gender differences in pain and analgesia: a consensus report
Greenspan, J. D., Craft, R. M., LeResche, L., Arendt-Nielsen, L., Berkley, K. J., Fillingim, R. B., Gold, M. S., Holdcroft, A., Lautenbacher, S., Mayer, E. A., et al. (2007) · Pain · doi:10.1016/j.pain.2007.10.014 · Cited by 1,033
Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms
LaMotte, R. H., Shain, C. N., Simone, D. A., & Tsai, E. (1991) · Journal of Neurophysiology · doi:10.1152/jn.1991.66.1.190 · Cited by 936
Somatic symptom reporting in women and men
Barsky, A. J., Peekna, H. M., & Borus, J. F. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016004266.x · Cited by 816
A systematic literature review of 10 years of research on sex/gender and experimental pain perception – Part 1: Are there really differences between women and men?
Racine, M., Tousignant-Laflamme, Y., Kloda, L. A., Dion, D., Dupuis, G., & Choinière, M. (2012) · Pain · doi:10.1016/j.pain.2011.11.025 · Cited by 691
Self-citation
Exploring the Biological Contributions to Human Health
Institute of Medicine (2001) · National Academies Press eBooks · doi:10.17226/10028 · Cited by 658
Using Chronic Pain to Predict Depressive Morbidity in the General Population
Ohayon, M. M., & Schatzberg, A. F. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.1.39 · Cited by 617
Sex differences in pain perception
Wiesenfeld‐Hallin, Z. (2005) · Gender Medicine · doi:10.1016/s1550-8579(05)80042-7 · Cited by 606
A meta-analytic review of pain perception across the menstrual cycle
Riley, J. L., Robinson, M. E., Wise, E. A., & Price, D. D. (1999) · Pain · doi:10.1016/s0304-3959(98)00258-9 · Cited by 591
Peripheral suppression of first pain and central summation of second pain evoked by noxious heat pulses
Price, D. D., Hu, J. W., Dubner, R. A., & Gracely, R. H. (1977) · Pain · doi:10.1016/0304-3959(77)90035-5 · Cited by 589
Sex differences in pain and analgesia: the role of gonadal hormones
Craft, R. M., Mogil, J. S., & Aloisi, A. M. (2004) · European Journal of Pain · doi:10.1016/j.ejpain.2004.01.003 · Cited by 570
Sex-related hormonal influences on pain and analgesic responses
Fillingim, R. B., & Ness, T. J. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00017-8 · Cited by 554
Recommendations on terminology and practice of psychophysical DNIC testing
Yarnitsky, D., Arendt‐Nielsen, L., Bouhassira, D., Edwards, R. R., Fillingim, R. B., Granot, M., Hansson, P. T., Lautenbacher, S., Marchand, S., & Wilder‐Smith, O. H. G. (2010) · European Journal of Pain · doi:10.1016/j.ejpain.2010.02.004 · Cited by 535
An inventory for the measurement of self‐reported stress and arousal
Mackay, C., Cox, T., Burrows, G., & Lazzerini, T. (1978) · British Journal of Social and Clinical Psychology · doi:10.1111/j.2044-8260.1978.tb00280.x · Cited by 533
Sex, gender, and pain: women and men really are different
Fillingim, R. B. (2000) · Current Review of Pain · doi:10.1007/s11916-000-0006-6 · Cited by 488
Gender differences in the responses to noxious stimuli
Fillingim, R. B., & Maixner, W. D. (1995) · Pain Forum · doi:10.1016/s1082-3174(11)80022-x · Cited by 475
Modulation of pain by estrogens
Craft, R. M. (2007) · Pain · doi:10.1016/j.pain.2007.09.028 · Cited by 466
Gender differences in pressure pain threshold in healthy humans
Chesterton, L. S., Barlas, P., Foster, N. E., Baxter, D. G., & Wright, C. C. (2003) · Pain · doi:10.1016/s0304-3959(02)00330-5 · Cited by 460
Negative and positive components of psychological masculinity and femininity and their relationships to self-reports of neurotic and acting out behaviors.
SPENCE, J. T., Helmreich, R. L., & Holahan, C. K. (1979) · Journal of Personality and Social Psychology · doi:10.1037//0022-3514.37.10.1673 · Cited by 455
Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament
Kim, H., Neubert, J. K., Miguel, A. S., Xu, K., Krishnaraju, R. K., Iadarola, M. J., Goldman, D. A., & Dionne, R. A. (2004) · Pain · doi:10.1016/j.pain.2004.02.027 · Cited by 427
Gender role expectations of pain: relationship to sex differences in pain
Robinson, M. E., Riley, J. L., Myers, C. D., Papas, R. K., Wise, E. A., Waxenberg, L. B., & Fillingim, R. B. (2001) · The Journal of Pain · doi:10.1054/jpai.2001.24551 · Cited by 423
Interactions between cardiovascular and pain regulatory systems
Randich, A., & Maixner, W. D. (1984) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(84)90057-5 · Cited by 413
Gender differences in Pain
Rollman, G. B. (1995) · Pain Forum · doi:10.1016/s1082-3174(11)80026-7 · Cited by 399
Pronociceptive and Antinociceptive Effects of Estradiol through Endogenous Opioid Neurotransmission in Women
Smith, Y. R., Stohler, C. S., Nichols, T. E., Bueller, J. A., Koeppe, R. A., & Zubieta, J. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.5223-05.2006 · Cited by 386
Diffuse noxious inhibitory controls (DNIC) attenuate temporal summation of second pain in normal males but not in normal females or fibromyalgia patients
Staud, R. M., Robinson, M. E., Vierck, C. J., & Price, D. D. (2002) · Pain · doi:10.1016/s0304-3959(02)00325-1 · Cited by 383
Stress-induced analgesia: adaptive pain suppression
Amit, Z., & Galina, Z. H. (1986) · Physiological Reviews · doi:10.1152/physrev.1986.66.4.1091 · Cited by 382
Determinants of endogenous analgesia magnitude in a diffuse noxious inhibitory control (DNIC) paradigm: Do conditioning stimulus painfulness, gender and personality variables matter?
Granot, M., Weissman-Fogel, I., Crispel, Y., Pud, D., Granovsky, Y., Sprecher, E., & Yarnitsky, D. (2008) · Pain · doi:10.1016/j.pain.2007.06.029 · Cited by 371
Negative and positive components of psychological masculinity and femininity and their relationships to self-reports of neurotic and acting out behaviors.
SPENCE, J. T., Helmreich, R. L., & Holahan, C. K. (1979) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.37.10.1673 · Cited by 370
μ-Opioid Receptor-Mediated Antinociceptive Responses Differ in Men and Women
Zubieta, J.-K., Smith, Y. R., Bueller, J. A., Xu, Y., Kilbourn, M. R., Jewett, D. M., Meyer, C. R., Koeppe, R. A., & Stohler, C. S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-12-05100.2002 · Cited by 363
The A118G single nucleotide polymorphism of the μ-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans
Fillingim, R. B., Kaplan, L., Staud, R. M., Ness, T. J., Glover, T. L., Campbell, C. M., Mogil, J. S., & Wallace, M. R. (2005) · Journal of Pain · doi:10.1016/j.jpain.2004.11.008 · Cited by 362
Gender role expectations of pain: relationship to experimental pain perception
Wise, E. A., Price, D. D., Myers, C. D., Heft, M. W., & Robinson, M. E. (2002) · Pain · doi:10.1016/s0304-3959(01)00473-0 · Cited by 359
Spatial and temporal transformations of input to spinothalamic tract neurons and their relation to somatic sensations
Price, D. D., Hayes, R. L., Ruda, M. A., & Dubner, R. A. (1978) · Journal of Neurophysiology · doi:10.1152/jn.1978.41.4.933 · Cited by 354
Windup leads to characteristics of central sensitization
Li, J., Simone, D. A., & Larson, A. A. (1999) · Pain · doi:10.1016/s0304-3959(98)00154-7 · Cited by 343
Individual Differences in Pain Sensitivity: Measurement, Causation, and Consequences
Nielsen, C. S., Staud, R. M., & Price, D. D. (2009) · Journal of Pain · doi:10.1016/j.jpain.2008.09.010 · Cited by 342
Hypertension-Associated Hypalgesia
Ghione, S. (1996) · Hypertension · doi:10.1161/01.hyp.28.3.494 · Cited by 340
Gender differences in pain perception and patterns of cerebral activation during noxious heat stimulation in humans
Paulson, P. E., Minoshima, S., Morrow, T. J., & Casey, K. L. (1998) · Pain · doi:10.1016/s0304-3959(98)00048-7 · Cited by 325
Baroreceptor Activation Reduces Reactivity to Noxious Stimulation: Implications for Hypertension
Dworkin, B. R., Filewich, R. J., Miller, N. E., Craigmyle, N., & Pickering, T. G. (1979) · Science · doi:10.1126/science.472749 · Cited by 317
Social Support and Experimental Pain
Brown, J. L., Sheffield, D., Leary, M. R., & Robinson, M. E. (2003) · Psychosomatic Medicine · doi:10.1097/01.psy.0000030388.62434.46 · Cited by 299
Diffuse Noxious Inhibitory Controls (DNIC)
Bars, D. L., & Willer, J. C. (2008) · Elsevier eBooks · doi:10.1016/b978-012370880-9.00193-6 · Cited by 292
Sex differences in temporal summation but not sensory-discriminative processing of thermal pain
Fillingim, R. B., Maixner, W., Kincaid, S., & Silva, S. (1998) · Pain · doi:10.1016/s0304-3959(97)00214-5 · Cited by 289
Gender differences in pain
Giles, B. E., & Walker, J. S. (1999) · Current Opinion in Anaesthesiology · doi:10.1097/00001503-199910000-00017 · Cited by 288
Gender Differences in Pain and Pain Behavior: The Role of Catastrophizing
Sullivan, M. J. L., Tripp, D. A., & Santor, D. (2000) · Cognitive Therapy and Research · doi:10.1023/a:1005459110063 · Cited by 285
Gender differences in pain modulation by diffuse noxious inhibitory controls: a systematic review
Popescu, A., LeResche, L., Truelove, E. L., & Drangsholt, M. T. (2010) · Pain · doi:10.1016/j.pain.2010.05.013 · Cited by 265
Hypertension-Associated Hypalgesia
SergioGhione (1996) · Hypertension · Cited by 264
Diffuse Noxious Inhibitory Controls (DNIC) in Animals and in Man
Bars, D. L., Villanueva, L., Bouhassira, D., & Wilier, J. C. (1991) · Acupuncture in Medicine · doi:10.1136/aim.9.2.47 · Cited by 261
Gender, coping and the perception of pain
Keogh, E., & Herdenfeldt, M. (2002) · Pain · doi:10.1016/s0304-3959(01)00427-4 · Cited by 259
The effects of experimenter characteristics on pain reports in women and men
Kállai, I., Barke, A., & Voss, U. (2004) · Pain · doi:10.1016/j.pain.2004.08.008 · Cited by 259
Immunological changes in young and old adults during brief laboratory stress.
Naliboff, B. D., Benton, D. M., Solomon, G. F., Morley, J. E., Fahey, J. L., Bloom, E. T., Makinodan, T., & Gilmore, S. L. (1991) · Psychosomatic Medicine · doi:10.1097/00006842-199103000-00002 · Cited by 256
Sex, Gender, and Pain
Fillingim, R. B. (2017) · Principles of Gender-Specific Medicine · doi:10.1016/b978-0-12-803506-1.00038-3 · Cited by 256
The activation of bulbo-spinal controls by peripheral nociceptive inputs: diffuse noxious inhibitory controls.
Villanueva, L., & Bars, D. L. (1995) · PubMed · Cited by 250
Catastrophizing as a mediator of sex differences in pain: differential effects for daily pain versus laboratory-induced pain
Edwards, R. R., Haythornthwaite, J. A., Sullivan, M. J., & Fillingim, R. B. (2004) · Pain · doi:10.1016/j.pain.2004.07.012 · Cited by 250
Sex-Related Differences in Human Pain and Rat Afferent Discharge Evoked by Injection of Glutamate Into the Masseter Muscle
Cairns, B. E., Hu, J. W., Arendt‐Nielsen, L., Sessle, B. J., & Svensson, P. J. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.2.782 · Cited by 244
Sex hormones, central nervous system and pain.
Aloisi, A., & Bonifazi, M. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.12.002 · Cited by 239
Individual differences in pain responses
Fillingim, R. B. (2005) · Current Rheumatology Reports · doi:10.1007/s11926-005-0018-7 · Cited by 231
The relationship of sex and clinical pain to experimental pain responses
Fillingim, R. B., Edwards, R. R., & Powell, T. (1999) · Pain · doi:10.1016/s0304-3959(99)00128-1 · Cited by 223
Effects of catastrophizing on pain perception and pain modulation
Weissman-Fogel, I., Sprecher, E., & Pud, D. (2008) · Experimental Brain Research · doi:10.1007/s00221-007-1206-7 · Cited by 214
Psychosocial contributions to sex-correlated differences in pain
Myers, C. D., Riley, J. L., & Robinson, M. E. (2003) · The Clinical Journal of Pain · doi:10.1097/00002508-200307000-00005 · Cited by 211
Does experimental pain response vary across the menstrual cycle? A methodological review
Sherman, J. J., & LeResche, L. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00920.2005 · Cited by 206
Can anxiety help us tolerate pain?
Al’Absi, M., & Rokke, P. D. (1991) · Pain · doi:10.1016/0304-3959(91)90032-s · Cited by 205
Contact heat-evoked temporal summation: Tonic versus repetitive-phasic stimulation
Granot, M., Granovsky, Y., Sprecher, E., Nir, R., & Yarnitsky, D. (2006) · Pain · doi:10.1016/j.pain.2006.02.003 · Cited by 203
Group differences in pain modulation: pain-free women compared to pain-free men and to women with TMD
Bragdon, E. E., Light, K. C., Costello, N. L., Sigurðsson, Á., Bunting, S., Bhalang, K., & Maixner, W. D. (2002) · Pain · doi:10.1016/s0304-3959(01)00451-1 · Cited by 196
Diffuse noxious inhibitory controls (DNIC) in animals and in man.
Bars, D. L., Villanueva, L., Bouhassira, D., & Jc, W. (1992) · PubMed · Cited by 196
Glutamate-evoked pain and mechanical allodynia in the human masseter muscle
Svensson, P. J., Cairns, B. E., Wang, K., Hu, J. W., Graven‐Nielsen, T., Arendt‐Nielsen, L., & Sessle, B. J. (2003) · Pain · doi:10.1016/s0304-3959(02)00079-9 · Cited by 195
The effect of experimenter gender on autonomic and subjective responses to pain stimuli
Aslaksen, P. M., Myrbakk, I. N., Høifødt, R. S., & Flaten, M. A. (2006) · Pain · doi:10.1016/j.pain.2006.10.011 · Cited by 194
Influences of gender role and anxiety on sex differences in temporal summation of pain
Robinson, M. E., Wise, E. A., Gagnon, C., Fillingim, R. B., & Price, D. D. (2004) · The Journal of Pain · doi:10.1016/j.jpain.2003.11.004 · Cited by 193
Gonadal Hormones and Sex Differences in Pain Reactivity
Aloisi, A. M. (2003) · Clinical Journal of Pain · doi:10.1097/00002508-200305000-00004 · Cited by 189
Temporal Summation of Pain Evoked by Mechanical Stimulation in Deep and Superficial Tissue
Nie, H., Arendt‐Nielsen, L., Andersen, H., & Graven‐Nielsen, T. (2005) · Journal of Pain · doi:10.1016/j.jpain.2005.01.352 · Cited by 184
Fear of Pain, Pain Catastrophizing, and Acute Pain Perception: Relative Prediction and Timing of Assessment
Hirsh, A. T., George, S. Z., Bialosky, J. E., & Robinson, M. E. (2008) · Journal of Pain · doi:10.1016/j.jpain.2008.03.012 · Cited by 184
An experimental model to measure excitatory and inhibitory pain mechanisms in humans
Tousignant-Laflamme, Y., Pagé, S., Goffaux, P., & Marchand, S. (2008) · Brain Research · doi:10.1016/j.brainres.2008.06.120 · Cited by 182
A comparison of the effects of preferred music, arithmetic and humour on cold pressor pain
Mitchell, L., MacDonald, R., & Brodie, E. E. (2005) · European Journal of Pain · doi:10.1016/j.ejpain.2005.03.005 · Cited by 178
Sex differences in pain perception and anxiety. A psychophysical study with topical capsaicin
Frot, M., Feine, J. S., & Bushnell, C. M. (2004) · Pain · doi:10.1016/j.pain.2003.11.017 · Cited by 171
Gender differences in temporal summation of mechanically evoked pain
Sarlani, E., & Greenspan, J. D. (2002) · Pain · doi:10.1016/s0304-3959(02)00015-5 · Cited by 171
Altering gender role expectations: effects on pain tolerance, pain threshold, and pain ratings
Robinson, M. E., Gagnon, C. M., Riley, J. L., & Price, D. D. (2003) · Journal of Pain · doi:10.1016/s1526-5900(03)00559-5 · Cited by 169
An evaluation of sex differences in psychological and physiological responses to experimentally-induced pain: a path analytic description
Dixon, K. E., Thorn, B. E., & Ward, C. L. (2004) · Pain · doi:10.1016/j.pain.2004.08.017 · Cited by 169
Avoidance versus focused attention and the perception of pain: differential effects for men and women
Keogh, E., Hatton, K., & Ellery, D. (2000) · Pain · doi:10.1016/s0304-3959(99)00270-5 · Cited by 169
Culture and Gender Effects in Pain Beliefs and the Prediction of Pain Tolerance
Nayak, S., Shiflett, S. C., Eshun, S., & Levine, F. M. (2000) · Cross-Cultural Research · doi:10.1177/106939710003400203 · Cited by 169
Establishing a Link Between Heart Rate and Pain in Healthy Subjects: A Gender Effect
Tousignant‐Laflamme, Y., Rainville, P., & Marchand, S. (2005) · Journal of Pain · doi:10.1016/j.jpain.2005.01.351 · Cited by 168
A comparison of diffuse noxious inhibitory controls in men and women
France, C. R., & Suchowiecki, S. (1999) · Pain · doi:10.1016/s0304-3959(98)00272-3 · Cited by 165
Cluster analysis of multiple experimental pain modalities
Hastie, B. A., Riley, J. L., Robinson, M. E., Glover, T. L., Campbell, C. M., Staud, R. M., & Fillingim, R. B. (2005) · Pain · doi:10.1016/j.pain.2005.04.016 · Cited by 161
Dose response of isometric contractions on pain perception in healthy adults
HOEGER BEMENT, M. K., DICAPO, J., RASIARMOS, R., & HUNTER, S. K. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31817eeecc · Cited by 156
Phasic pupil dilation response to noxious stimulation in normal volunteers: Relationship to brain evoked potentials and pain report
Chapman, C. R., Oka, S., Bradshaw, D. H., Jacobson, R. C., & Donaldson, G. W. (1999) · Psychophysiology · doi:10.1017/s0048577299970373 · Cited by 156
Bridging the gap between pain and gender research: A selective literature review
Bernardes, S. F., Keogh, E., & Lima, M. L. (2007) · European Journal of Pain · doi:10.1016/j.ejpain.2007.08.007 · Cited by 154
Adrenocortical and hemodynamic predictors of pain perception in men and women
Al’Absi, M., Petersen, K. L., & Wittmers, L. E. (2002) · Pain · doi:10.1016/s0304-3959(01)00447-x · Cited by 154
Specific characteristics of the pain/depression association in the general population.
Ohayon, M. M. (2004) · PubMed · Cited by 153
Effects of diffuse noxious inhibitory controls on temporal summation of the RIII reflex in humans
Serrao, M., Rossi, P., Sandrini, G., Parisi, L., Amabile, G. A., Nappi, G., & Pierelli, F. (2004) · Pain · doi:10.1016/j.pain.2004.09.018 · Cited by 149
Sex differences in temporal characteristics of descending inhibitory control: an evaluation using repeated bilateral experimental induction of muscle pain
Ge, H.-Y., Madeleine, P., & Arendt-Nielsen, L. (2004) · Pain · doi:10.1016/j.pain.2004.03.005 · Cited by 146 · cited 4×
“– 1st injection [70,72], Lautenbacher et al.”
BackgroundInfluential
Comparing acceptance‐ and control‐based coping instructions on the cold‐pressor pain experiences of healthy men and women
Keogh, E., Bond, F. W., Hanmer, R., & Tilston, J. (2005) · European Journal of Pain · doi:10.1016/j.ejpain.2004.12.005 · Cited by 143
Experimental muscle pain impairs descending inhibition
Arendt‐Nielsen, L., Sluka, K. A., & Nie, H. (2008) · Pain · doi:10.1016/j.pain.2008.09.027 · Cited by 142
The Relationship between Cardiovascular and Pain Regulatory Systems
Zamir, N., & Maixner, W. (1986) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1986.tb14641.x · Cited by 139
Sex, gender, and blood pressure: contributions to experimental pain report
Myers, C. D., Robinson, M. E., Riley, J. L., & Sheffield, D. (2001) · Psychosomatic Medicine · doi:10.1097/00006842-200107000-00004 · Cited by 138
Is self-reported childhood abuse history associated with pain perception among healthy young women and men?
Fillingim, R. B., & Edwards, R. R. (2005) · The Clinical Journal of Pain · doi:10.1097/01.ajp.0000149801.46864.39 · Cited by 133
Stress-induced behavioral responses and multiple opioid systems in the brain
Yamada, K., & Nabeshima, T. (1995) · Behavioural Brain Research · doi:10.1016/0166-4328(94)00150-e · Cited by 132
Excitatory and inhibitory pain mechanisms during the menstrual cycle in healthy women
Tousignant‐Laflamme, Y., & Marchand, S. (2009) · Pain · doi:10.1016/j.pain.2009.06.018 · Cited by 132
Sex differences in temporal summation of pain and aftersensations following repetitive noxious mechanical stimulation
Sarlani, E., Grace, E. G., Reynolds, M. A., & Greenspan, J. D. (2004) · Pain · doi:10.1016/j.pain.2004.01.019 · Cited by 132
Effects of Emotion on Pain Reports, Tolerance and Physiology
Carter, L. E., McNeil, D. W., Vowles, K. E., Sorrell, J. T., Turk, C. L., Ries, B. J., & Hopko, D. R. (2002) · Pain Research and Management · doi:10.1155/2002/426193 · Cited by 131
Fear of pain, not pain catastrophizing, predicts acute pain intensity, but neither factor predicts tolerance or blood pressure reactivity: An experimental investigation in pain‐free individuals
George, S. Z., Dannecker, E. A., & Robinson, M. E. (2005) · European Journal of Pain · doi:10.1016/j.ejpain.2005.06.007 · Cited by 131
The relationship of gender to pain
Vallerand, A. H., & Polomano, R. C. (2000) · Pain Management Nursing · doi:10.1053/jpmn.2000.9759 · Cited by 128
Sex Differences and Hormonal Influences on Response to Cold Pressor Pain in Humans
Kowalczyk, W. J., Evans, S. M., Bisaga, A. M., Sullivan, M. A., & Comer, S. D. (2006) · Journal of Pain · doi:10.1016/j.jpain.2005.10.004 · Cited by 128
A human experimental capsaicin model for trigeminal sensitization. Gender-specific differences
Gazerani, P., Andersen, O. K., & Arendt‐Nielsen, L. (2005) · Pain · doi:10.1016/j.pain.2005.08.009 · Cited by 124
Effect of isometric exercise on pain perception and blood pressure in men and women
Koltyn, K. F., Trine, M. R., Stegner, A. J., & Tobar, D. A. (2001) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200102000-00018 · Cited by 123
Personality factors in the explanation of sex differences in pain catastrophizing and response to experimental pain
Thorn, B. E., Clements, K. L., Ward, L. C., Dixon, K. E., Kersh, B. C., Boothby, J. L., & Chaplin, W. F. (2004) · The Clinical Journal of Pain · doi:10.1097/00002508-200409000-00001 · Cited by 121
Anxiety sensitivity and pain: Generalisability across noxious stimuli
Thompson, T., Keogh, E., French, C. C., & Davis, R. (2007) · Pain · doi:10.1016/j.pain.2007.04.018 · Cited by 120
Sex differences in drug- and non-drug-induced analgesia
Craft, R. M. (2003) · Life Sciences · doi:10.1016/s0024-3205(03)00178-4 · Cited by 118
The Effect of Anxiety Sensitivity and Gender on the Experience of Pain
Keogh, E., & Birkby, J. (1999) · Cognition & Emotion · doi:10.1080/026999399379096 · Cited by 117
Role of gender norms and group identification on hypothetical and experimental pain tolerance
Pool, G. J., Schwegler, A. F., Theodore, B. R., & Fuchs, P. N. (2006) · Pain · doi:10.1016/j.pain.2006.10.008 · Cited by 116
Theoretical review: altered pain regulatory systems in chronic pain
Bruehl, S. P., McCubbin, J. A., & Harden, R. N. (1999) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(99)00039-1 · Cited by 111
Gender differences in patterns of cerebral activation during equal experience of painful laser stimulation
Derbyshire, S. W. G., Nichols, T. E., Firestone, L. L., Townsend, D. W., & Jones, A. K. P. (2002) · Journal of Pain · doi:10.1054/jpai.2002.126788 · Cited by 111
Gender differences in brain activity evoked by muscle and cutaneous pain: A retrospective study of single-trial fMRI data
Henderson, L. A., Gandevia, S. C., & Macefield, V. G. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2007.10.045 · Cited by 108
Pain perception to the cold pressor test during the menstrual cycle in relation to estrogen levels and a comparison with men
Hellström, B., & Lundberg, U. (2000) · Integrative Psychological and Behavioral Science · doi:10.1007/bf02688772 · Cited by 104
Sex-Dependent Components of the Analgesia Produced by Athletic Competition
Sternberg, W. F., Boka, C., Kass, L. K., Alboyadjia, A., & Gracely, R. H. (2001) · Journal of Pain · doi:10.1054/jpai.2001.18236 · Cited by 102
The QUORUM statement
Clarke, M. J. (2000) · The Lancet · doi:10.1016/s0140-6736(05)72172-3 · Cited by 100
EXPERIMENTAL PAIN THRESHOLDS INFLUENCED BY SEX OF EXPERIMENTER
Gijsbers, K., & Nicholson, F. (2005) · Perceptual and Motor Skills · doi:10.2466/pms.101.3.803-807 · Cited by 99
Does past pain influence current pain: biological and psychosocial models of sex differences
Rollman, G. B., Abdel‐Shaheed, J., Gillespie, J. M., & Jones, K. S. (2004) · European Journal of Pain · doi:10.1016/j.ejpain.2004.03.002 · Cited by 99
Sex differences in endogenous pain modulation by distracting and painful conditioning stimulation
Quiton, R. L., & Greenspan, J. D. (2007) · Pain · doi:10.1016/j.pain.2007.09.001 · Cited by 98
Gender differences in cortical representation of rectal distension in healthy humans
Kern, M., Jaradeh, S. S., Arndorfer, R. C., Jesmanowicz, A., Hyde, J. S., & Shaker, R. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.281.6.g1512 · Cited by 98
Blood pressure but not cortisol mediates stress effects on subsequent pain perception in healthy men and women
Al’Absi, M., & Petersen, K. L. (2003) · Pain · doi:10.1016/s0304-3959(03)00300-2 · Cited by 96
Homotopic and heterotopic effects of endogenous analgesia in healthy volunteers
Pud, D., Sprecher, E., & Yarnitsky, D. (2005) · Neuroscience Letters · doi:10.1016/j.neulet.2005.01.037 · Cited by 94
Odors modulate pain perceptionA gender-specific effect
Marchand, S., & Arsenault, P. (2002) · Physiology & Behavior · doi:10.1016/s0031-9384(02)00703-5 · Cited by 93
Differential physiological effects during tonic painful hand immersion tests using hot and ice water
Streff, A., Kuehl, L. K., Michaux, G., & Anton, F. (2009) · European Journal of Pain · doi:10.1016/j.ejpain.2009.05.011 · Cited by 93
Long‐term fluctuations of pressure pain thresholds in healthy men, normally menstruating women and oral contraceptive users
Isselée, H., Laat, A. D., Bogaerts, K., & Lysens, R. (2001) · European Journal of Pain · doi:10.1053/eujp.2000.0213 · Cited by 92
Dispositional anxiety and the experience of pain: gender‐specific effects
Jones, A., Zachariae, R. H., & Arendt‐Nielsen, L. (2003) · European Journal of Pain · doi:10.1016/s1090-3801(02)00139-8 · Cited by 91
Sex Differences in Cortisol Response to Noxious Stress
Zimmer, C., Basler, H.-D., Vedder, H., & Lautenbacher, S. (2003) · Clinical Journal of Pain · doi:10.1097/00002508-200307000-00006 · Cited by 91
Gender, interpersonal transactions, and the perception of pain: An experimental analysis
Jackson, T., Iezzi, T., Chen, H., Ebnet, S., & Eglitis, K. (2005) · Journal of Pain · doi:10.1016/j.jpain.2004.12.004 · Cited by 91
Gender Differences in Pain Perception: The Mediating Role of Self-Efficacy Beliefs
Jackson, T., Iezzi, T., Gunderson, J., Nagasaka, T., & Fritch, A. M. (2002) · Sex Roles · doi:10.1023/a:1022077922593 · Cited by 90
Lack of sex differences in modulation of experimental intraoral pain by diffuse noxious inhibitory controls (DNIC)
Baad‐Hansen, L., Poulsen, H. F., Jensen, H. M., & Svensson, P. J. (2005) · Pain · doi:10.1016/j.pain.2005.05.006 · Cited by 90
Sex and gender differences in pain and inflammation: a rapidly maturing field
Berkley, K. J., Zalcman, S. S., & Simon, V. R. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00287.2006 · Cited by 86
Sex Differences in Naturally Occurring Leg Muscle Pain and Exertion During Maximal Cycle Ergometry
Cook, D. B., O’Connor, P. J., Oliver, S. E., & Lee, Y. (1998) · International Journal of Neuroscience · doi:10.3109/00207459809003340 · Cited by 86
Comparison of experimental and acute clinical pain responses in humans as pain phenotypes
Kim, H., Neubert, J. K., Rowan, J. S., Brahim, J. S., Iadarola, M. J., & Dionne, R. A. (2004) · Journal of Pain · doi:10.1016/j.jpain.2004.06.003 · Cited by 84
Real-time imaging of human cortical activity evoked by painful esophageal stimulation
Hobson, A. R., Furlong, P. L., Worthen, S. F., Hillebrand, A., Barnes, G. R., Singh, K. D., & Aziz, Q. (2005) · Gastroenterology · doi:10.1053/j.gastro.2004.12.033 · Cited by 84
Noise Stress and Human Pain Thresholds: Divergent Effects in Men and Women
Rhud, J. L., & Meagher, M. W. (2001) · Journal of Pain · doi:10.1054/jpai.2000.19947 · Cited by 82
Experimentally induced anger, cardiovascular reactivity, and pain sensitivity
Janssen, S. A., Spinhoven, P., & BROSSCHOT, J. F. (2001) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(01)00222-7 · Cited by 81
Delayed onset muscle soreness in neck/shoulder muscles
Nie, H., Kawczyński, A., Madeleine, P., & Arendt‐Nielsen, L. (2005) · European Journal of Pain · doi:10.1016/j.ejpain.2004.12.009 · Cited by 81
The Influence of Experimenter Gender and Race on Pain Reporting: Does Racial or Gender Concordance Matter?
Weisse, C. S., Foster, K. K., & Fisher, E. A. (2005) · Pain Medicine · doi:10.1111/j.1526-4637.2005.05004.x · Cited by 81
Sex Differences in Facial Encoding of Pain
Miriam Kunz, A., Gruber, A., & Lautenbacher, S. (2006) · Journal of Pain · doi:10.1016/j.jpain.2006.04.012 · Cited by 80
Gender differences in pain modulation evoked by repeated injections of glutamate into the human trapezius muscle
Ge, H., Madeleine, P., & Arendt‐Nielsen, L. (2004) · Pain · doi:10.1016/j.pain.2004.09.041 · Cited by 80
The association of hormone replacement therapy with experimental pain responses in postmenopausal women
Fillingim, R. B., & Edwards, R. R. (2001) · Pain · doi:10.1016/s0304-3959(01)00256-1 · Cited by 79
Sex-dependent effects of reported familial pain history on recent pain complaints and experimental pain responses
Fillingim, R. B., Edwards, R. R., & Powell, T. (2000) · Pain · doi:10.1016/s0304-3959(00)00239-6 · Cited by 79
Social influence and pain response in women and men
McClelland, L. E., & McCubbin, J. A. (2008) · Journal of Behavioral Medicine · doi:10.1007/s10865-008-9163-6 · Cited by 75
Are There Gender Differences in Pain Perception?
Soetanto, A. L. F., Chung, J. W. Y., & Wong, T. K. S. (2006) · Journal of Neuroscience Nursing · doi:10.1097/01376517-200606000-00006 · Cited by 75
Sex differences in the cerebral BOLD signal response to painful heat stimuli
Moulton, E. A., Keaser, M. L., Gullapalli, R. P., Maitra, R., & Greenspan, J. D. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00084.2006 · Cited by 75
Effects of subcutaneous administration of glutamate on pain, sensitization and vasomotor responses in healthy men and women
Gazerani, P., Wang, K., Cairns, B. E., Svensson, P. J., & Arendt‐Nielsen, L. (2006) · Pain · doi:10.1016/j.pain.2006.06.015 · Cited by 74
The effects of DNIC-type inhibition on temporal summation compared to single pulse processing: Does sex matter?
Lautenbacher, S., Miriam Kunz, A., & Burkhardt, S. (2008) · Pain · doi:10.1016/j.pain.2008.09.019 · Cited by 74
Psychosocial mediators of sex differences in pain responsivity
Sanford, S. D., Kersh, B. C., Thorn, B. E., Rich, M. A., & Ward, L. C. (2002) · Journal of Pain · doi:10.1054/jpai.2002.xb30066 · Cited by 72
Gender Differences in Pain and Secondary Hyperalgesia After Heat/Capsaicin Sensitization in Healthy Volunteers
Jensen, M. T., & Petersen, K. L. (2006) · Journal of Pain · doi:10.1016/j.jpain.2005.10.013 · Cited by 72
Prior pain experience: influence on the observation of experimental pain in men and women
Robinson, M. E., & Wise, E. A. (2004) · Journal of Pain · doi:10.1016/j.jpain.2004.04.003 · Cited by 69
Competition alters the perception of noxious stimuli in male and female athletes
Sternberg, W. F., Bailin, D., Grant, M. A. B., & Gracely, R. H. (1998) · Pain · doi:10.1016/s0304-3959(98)00050-5 · Cited by 66
Sex differences in delayed onset muscle soreness.
Dannecker, E. A., Koltyn, K. F., Riley, J. L., & Robinson, M. E. (2003) · PubMed · Cited by 65
Effects of aging on contact heat‐evoked potentials: The physiological assessment of thermal perception
Chao, C., Hsieh, S., Chiu, M., Tseng, M., & Chang, Y. (2007) · Muscle & Nerve · doi:10.1002/mus.20815 · Cited by 65
Relationship of ethnicity, gender, and ambulatory blood pressure to pain sensitivity: effects of individualized pain rating scales
Campbell, T. S., Hughes, J. W., Girdler, S. S., Maixner, W. D., & Sherwood, A. (2004) · Journal of Pain · doi:10.1016/j.jpain.2004.02.305 · Cited by 64
The spatial characteristics of the painful thermal grill illusion ☆
Defrin, R., Sheraizin, A., Bezalel, A., Mantzur, O., & Arendt‐Nielsen, L. (2008) · Pain · doi:10.1016/j.pain.2008.02.012 · Cited by 63
Across- and within-session variability of ratings of painful contact heat stimuli
Quiton, R. L., & Greenspan, J. D. (2007) · Pain · doi:10.1016/j.pain.2007.08.034 · Cited by 63
Reduced tolerance and cardiovascular response to ischemic pain in minor depression
Piñerúa-Shuhaibar, L., Prieto-Rincón, D., Ferrer, A., Bonilla, E., Maixner, W. D., & Suárez-Roca, H. (1999) · Journal of Affective Disorders · doi:10.1016/s0165-0327(99)00051-8 · Cited by 61
Gender, anxiety, and experimental pain sensitivity: an overview.
Jones, A., & Zachariae, R. H. (2002) · PubMed · Cited by 60
Sex differences in pain perception and cardiovascular responses in persons with parental history for hypertension
Al’Absi, M., Buchanan, T. W., Marrero, A., & Lovallo, W. R. (1999) · Pain · doi:10.1016/s0304-3959(99)00122-0 · Cited by 57
Sex Differences and Incentive Effects on Perceptual and Cardiovascular Responses to Cold Pressor Pain
Lowery, D., Fillingim, R. B., & Wright, R. A. (2003) · Psychosomatic Medicine · doi:10.1097/01.psy.0000033127.11561.78 · Cited by 57
Site-dependent and subject-related variations in perioral thermal sensitivity
Essick, G. K., Guest, S., Martinez, E., Chen, C., & McGlone, F. (2004) · Somatosensory & Motor Research · doi:10.1080/08990220400012414 · Cited by 56
Investigation of the interactive effects of gender and psychological factors on pain response
Jones, A., & Zachariae, R. H. (2004) · British Journal of Health Psychology · doi:10.1348/1359107041557101 · Cited by 55
Sensory lateralization in pain subjective perception for noxious heat stimulus
Lugo, M., Istúriz, G., Lara, C., García, N., & Eblén-Zajjur, A. (2002) · Somatosensory & Motor Research · doi:10.1080/0899022021000009125 · Cited by 55
Hypoalgesia in the Referred Pain Areas After Bilateral Injections of Hypertonic Saline Into the Trapezius Muscles of Men and Women: A Potential Experimental Model of Gender-Specific Differences
Ge, H., Madeleine, P., Cairns, B. E., & Arendt‐Nielsen, L. (2005) · Clinical Journal of Pain · doi:10.1097/01.ajp.0000149799.01123.38 · Cited by 55
Independent effects of emotion and attention on sensory and affective pain perception
Kenntner‐Mabiala, R., Weyers, P., & Pauli, P. (2007) · Cognition & Emotion · doi:10.1080/02699930701252249 · Cited by 51
Sex differentiated responses to intranasal trigeminal stimuli
Lundström, J. N., Frasnelli, J., Larsson, M. U., & Hummel, T. R. (2005) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2005.01.003 · Cited by 51
The Meeting of Pain and Depression: Comorbidity in Women
Meana, M. (1998) · The Canadian Journal of Psychiatry · doi:10.1177/070674379804300902 · Cited by 51
Sex and gender differences in pain and its relief
Holdcroft, A., & Berkley, K. J. (2006) · Elsevier eBooks · doi:10.1016/b0-443-07287-6/50080-1 · Cited by 50
The effect of situation–evoked anxiety and gender on pain report using the cold pressor test
Jones, A., Spindler, H., Jørgensen, M. M., & Zachariae, R. H. (2002) · Scandinavian Journal of Psychology · doi:10.1111/1467-9450.00299 · Cited by 48
Hormone‐dependent fluctuations of pressure pain threshold and tactile threshold of the temporalis and masseter muscle
Drobek, W., Schoenaers, J. H. A., & Laat, A. D. (2002) · Journal of Oral Rehabilitation · doi:10.1046/j.1365-2842.2002.00988.x · Cited by 47
Integrating the Dimensions of Sex and Gender into Basic Life Sciences Research: Methodologic and Ethical Issues
Holdcroft, A. (2007) · Gender Medicine · doi:10.1016/s1550-8579(07)80048-9 · Cited by 46
Sex differences in perceptual and cardiovascular responses to pain: the influence of a perceived ability manipulation
Fillingim, R. B., Browning, A. D., Powell, T., & Wright, R. A. (2002) · Journal of Pain · doi:10.1054/jpai.2002.128067 · Cited by 42
Gender difference in jaw pain induced by clenching
Plesh, O., Curtis, D. A., Hall, L., & Miller, A. (1998) · Journal of Oral Rehabilitation · doi:10.1111/j.1365-2842.1998.00270.x · Cited by 42
Evidence that diffuse noxious inhibitory controls (DNIC) are mediated by a final post-synaptic inhibitory mechanism
Villanueva, L., Cadden, S. W., & Bars, D. L. (1984) · Brain Research · doi:10.1016/0006-8993(84)91147-8 · Cited by 41
Spatial summation of heat pain in males and females
Lautenbacher, S. (2001) · Somatosensory & Motor Research · doi:10.1080/135578501012006192-1 · Cited by 41
Effects of stress and relaxation on capsaicin-induced pain
Logan, H. L., Lutgendorf, S. K., Rainville, P., Sheffield, D., Iverson, K., & Lubaroff, D. M. (2001) · Journal of Pain · doi:10.1054/jpai.2001.21597 · Cited by 40
Musically induced arousal affects pain perception in females but not in males: A psychophysiological examination
Kenntner‐Mabiala, R., Gorges, S., Alpers, G. W., Lehmann, A. C., & Pauli, P. (2006) · Biological Psychology · doi:10.1016/j.biopsycho.2006.10.005 · Cited by 40
Assessing the Relationship Between Cold Pressor Pain Responses and Dimensions of the Anxiety Sensitivity Profile in Healthy Men and Women
Keogh, E., Barlow, C., Mounce, C., & Bond, F. W. (2006) · Cognitive Behaviour Therapy · doi:10.1080/16506070600898330 · Cited by 36
Interactions between spatial summation, 2‐point discrimination and habituation of heat pain
Defrin, R., Pope, G. E., & Davis, K. D. (2008) · European Journal of Pain · doi:10.1016/j.ejpain.2007.12.015 · Cited by 35
The Role of Mood States Underlying Sex Differences in the Perception and Tolerance of Pain
Garofalo, J. P., Lawler, C., Robinson, R., Morgan, M. M., & Kenworthy‐Heinige, T. (2006) · Pain Practice · doi:10.1111/j.1533-2500.2006.00084.x · Cited by 33
Hypertension and pain sensitivity: effects of gender and cardiovascular reactivity
Nyklı́ček, I., Vingerhoets, A. J. J. M., & van Heck, G. L. (1999) · Biological Psychology · doi:10.1016/s0301-0511(99)00006-x · Cited by 33
Site-specific, dose-dependent, and sex-related responses to the experimental pain model induced by intradermal injection of capsaicin to the foreheads and forearms of healthy humans.
Gazerani, P., Andersen, O. K., & Arendt‐Nielsen, L. (2007) · PubMed · Cited by 31
Somatosensory function following painful repetitive electrical stimulation of the human temporomandibular joint and skin
Ayesh, E., Jensen, T. S., & Svensson, P. J. (2006) · Experimental Brain Research · doi:10.1007/s00221-006-0801-3 · Cited by 30
Nociception and baroreceptor stimulation in hypertension‐prone men and women
Al’Absi, M., France, C. R., Ring, C., France, J. L., Harju, A., McIntyre, D. B., & Wittmers, L. E. (2005) · Psychophysiology · doi:10.1111/j.1469-8986.2005.00257.x · Cited by 30
Lack of Both Sex Differences and Influence of Resting Blood Pressure on Muscle Pain Intensity
Poudevigne, M. S., O’Connor, P. J., & Pasley, J. D. (2002) · Clinical Journal of Pain · doi:10.1097/00002508-200211000-00007 · Cited by 29
The analgesic response to stress: genetic and gender considerations.
Sternberg, W. F., & Liebeskind, J. C. (1995) · PubMed · Cited by 28
Does gender affect the relation between blood pressure and pain sensitivity?
Helfer, S. G., & McCubbin, J. A. (2001) · International Journal of Behavioral Medicine · doi:10.1207/s15327558ijbm0803_4 · Cited by 28
Differences Between Male and Female Responses to Painful Thermal and Mechanical Stimulation of the Human Esophagus
Pedersen, J., Reddy, H., Funch-Jensen, P. M., Arendt‐Nielsen, L., Gregersen, H. N., & Drewes, A. M. (2004) · Digestive Diseases and Sciences · doi:10.1023/b:ddas.0000037789.25734.06 · Cited by 27
Decreased sensitivity to self-inflicted pain
Braid, L., & Cahusac, P. (2006) · Pain · doi:10.1016/j.pain.2006.04.006 · Cited by 26
Fear of pain, not pain catastrophizing, predicts acute pain intensity, but neither factor predicts tolerance or blood pressure reactivity: An experimental investigation in pain-free individuals
George, S. Z., Dannecker, E. A., & Robinson, M. E. (2006) · Acute Pain · doi:10.1016/j.acpain.2006.08.021 · Cited by 24
Can a sexually dimorphic index of prenatal hormonal exposure be used to examine cold pressor pain perception in men and women?
Keogh, E., Mounce, C., & Brosnan, M. (2006) · European Journal of Pain · doi:10.1016/j.ejpain.2006.02.011 · Cited by 24

Research works printed but not linked: 1

Goldberg, 2000, Influence of success and failure on pain tolerance., Eur J Psychiatry, 14, 171

Sorted by citations

Sex differences in pain: a brief review of clinical and experimental findings
Bartley, E. J., & Fillingim, R. B. (2013) · British Journal of Anaesthesia · doi:10.1093/bja/aet127 · Cited by 2,168
The association of sleep and pain: an update and a path forward
Finan, P. H., Goodin, B. R., & Smith, M. T. (2013) · The Journal of Pain · doi:10.1016/j.jpain.2013.08.007 · Cited by 1,620
Sex differences in pain and pain inhibition: multiple explanations of a controversial phenomenon
Mogil, J. S. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3360 · Cited by 1,065
“Brave Men” and “Emotional Women”: A Theory-Guided Literature Review on Gender Bias in Health Care and Gendered Norms towards Patients with Chronic Pain
Samulowitz, A., Gremyr, I., Eriksson, E. M., & Hensing, G. K. E. (2018) · Pain Research and Management · doi:10.1155/2018/6358624 · Cited by 862
Evaluating psychosocial contributions to chronic pain outcomes
Meints, S. M., & Edwards, R. R. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.01.017 · Cited by 719

See all 451

Authors: Racine, M., Tousignant-Laflamme, Y., Kloda, L. A., Dion, D., Dupuis, G., & Choinière, M.
Affiliations: Université de Sherbrooke (CA)
McGill University (CA)
Université de Montréal (CA)
Université du Québec à Montréal (CA)
Centre Hospitalier de l’Université de Montréal (CA)
Corresponding author: Choinière, Manon
ORCID: Racine, Mélanie
Kloda, Lorie A.
Dupuis, Gilles
Choinière, Manon
Venue: Pain
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2012-03
Volume: 153
Issue: 3
Pages: 619-635
ISSN: 0304-3959 (ISSN-L)
DOI: 10.1016/j.pain.2011.11.026
OpenAlex: W2066329882
Cited by: 451
References: 210
Citations by year: 2026: 15 · 2025: 23 · 2024: 26 · 2023: 37 · 2022: 34 · 2021: 30 · 2020: 39 · 2019: 34 · 2018: 42 · 2017: 29 · 2016: 45 · 2015: 25 · 2014: 25 · 2013: 37 · 2012: 10
FWCI: 3.34
Type: journal article
Language: en
Open access: closed
Locations: Pain (publishedVersion)
PubMed (publishedVersion)
Funders: Canadian Institutes of Health Research
Topics: Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
Keywords: sex differences in pain perception, gender differences, pain sensitivity, biopsychosocial model, temporal summation, allodynia, secondary hyperalgesia, endogenous pain inhibition, depression, anxiety, cognitive factors, social factors, history of pain, hormonal factors, women's pain
MeSH terms: Biological Factors, Female, Humans, Longitudinal Studies, Male, Nervous System, Pain, Psychology, Sex Characteristics, Stress, Psychological, Databases, Bibliographic, Pain Threshold, Biomedical Research, Pain Perception

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A systematic literature review of 10 years of research on sex/gender and pain perception – Part 2: Do biopsychosocial factors alter pain sensitivity differently in women and men?

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks