The DOI matches its Crossref record; 243 of the 245 references it cites were found in a registry or an index.
Behavioral effects of neuropeptides in rodent models of depression and anxiety
Abstract
In recent years, studies have advocated neuropeptide systems as modulators for the behavioral states found in mood disorders such as depression and anxiety disorders. Neuropeptides have been tested in traditional animal models and screening procedures that have been validated by known antidepressants and anxiolytics. However, it has become clear that although these tests are very useful, neuropeptides have distinct behavioral effects and dose-dependent characteristics, and therefore, use of these tests with neuropeptides must be done with an understanding of their unique characteristics. This review will focus on the behavioral actions of neuropeptides and their synthetic analogs, particularly in studies utilizing various preclinical tests of depression and anxiety. Specifically, the following neuropeptide systems will be reviewed: corticotropin-releasing factor (CRF), urocortin (Ucn), teneurin C-terminal associated peptide (TCAP), neuropeptide Y (NPY), arginine vasopressin (AVP), oxytocin, the Tyr-MIF-1 family, cholecystokinin (CCK), galanin, and substance P. These neuropeptide systems each have a unique role in the regulation of stress-like behavior, and therefore provide intriguing therapeutic targets for mood disorder treatment.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Preclinical studies demonstrated that exogenous intravenous and intranasal oxytocin can influence fear related responses in rodents and monkeys respectively, reducing hiding behaviour during an open field test and attentional bias towards threatening facial expressions (Parr et al., 2013;Rotzinger et al., 2010).”
From Meta-analytic review of the effects of a single dose of intranasal oxytocin on threat processing in humans (2018) · cites this paper as Rotzinger et al., 2010
Citations
Cites
Depression: a new animal model sensitive to antidepressant treatments
PORSOLT, R. D., LE PICHON, M., & JALFRE, M. (1977) · Nature · doi:10.1038/266730a0 · Cited by 4,451
Vale, W., Spiess, J., Rivier, C., & Rivier, J. (1981) · Science · doi:10.1126/science.6267699 · Cited by 3,965
Vale, W., Spiess, J., RIVIER, C. L., & Rivier, J. (1982) · Obstetrical & Gynecological Survey · doi:10.1097/00006254-198205000-00013 · Cited by 3,904
Behavioural despair in rats: A new model sensitive to antidepressant treatments
Porsolt, R. D., Anton, G., Blavet, N., & Jalfre, M. (1978) · European Journal of Pharmacology · doi:10.1016/0014-2999(78)90118-8 · Cited by 3,138
Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00465-7 · Cited by 2,091
Willner, P., Towell, A., Sampson, D., Sophokleous, S., & Muscat, R. (1987) · Psychopharmacology · doi:10.1007/bf00187257 · Cited by 1,993
Cryan, J. F., Mombereau, C., & Vassout, A. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.03.009 · Cited by 1,674
Oxytocin Modulates Neural Circuitry for Social Cognition and Fear in Humans
Kirsch, P., Esslinger, C., Chen, Q., Mier, D., Lis, S., Siddhanti, S., Gruppe, H., Mattay, V. S., Gallhofer, B., & Meyer-Lindenberg, A. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3984-05.2005 · Cited by 1,639
Assessing antidepressant activity in rodents: recent developments and future needs
Cryan, J. F., Markou, A., & Lucki, I. (2002) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(02)02017-5 · Cited by 1,551
Vaughan, J. M., Donaldson, C. J., Bittencourt, J. C., Perrin, M. H., Lewis, K., Sutton, S. W., Chan, R. K. W., Turnbull, A. V., Lovejoy, D. A., RIVIER, C. L., et al. (1995) · Nature · doi:10.1038/378287a0 · Cited by 1,479
Self-citationThe role of corticotropin-releasing factor in depression and anxiety disorders
Arborelius, L., Owens, M., Plotsky, P., & Nemeroff, C. (1999) · Journal of Endocrinology · doi:10.1677/joe.0.1600001 · Cited by 1,378
Dunn, A. J., & Berridge, C. W. (1990) · Brain Research Reviews · doi:10.1016/0165-0173(90)90012-d · Cited by 1,352
A potent and selective endogenous agonist for the µ-opiate receptor
Zadina, J. E., Hackler, L., Ge, L.-J., & Kastin, A. J. (1997) · Nature · doi:10.1038/386499a0 · Cited by 1,309
Fear and anxiety: Animal models and human cognitive psychophysiology
Lang, P. J., Davis, M., & Öhman, A. (2000) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00343-8 · Cited by 1,162
Chronic mild stress-induced anhedonia: A realistic animal model of depression
Willner, P., Muscat, R., & Papp, M. (1992) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80194-0 · Cited by 1,160
Cryan, J. F., Valentino, R. J., & Lucki, I. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.03.008 · Cited by 1,138
Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors
Kramer, M. S., Cutler, N. R., Feighner, J. P., Shrivastava, R. K., Carman, J. S., Sramek, J. J., Reines, S. A., Liu, G. F., Snavely, D. B., Wyatt-Knowles, E. S., et al. (1998) · Science · doi:10.1126/science.281.5383.1640 · Cited by 1,071
Is the forced swimming test a suitable model for revealing antidepressant activity?
Borsini, F., & Meli, A. (1988) · Psychopharmacology · doi:10.1007/bf00176837 · Cited by 1,053
Anxiety, defence and the elevated plus-maze.
Rodgers, R., & Dalvi, A. (1997) · Neuroscience and Biobehavioral Reviews · doi:10.1016/s0149-7634(96)00058-9 · Cited by 1,028
Lewis, K., Li, C., Perrin, M. H., Blount, A., Kunitake, K., Donaldson, C., Vaughan, J., Reyes, T. M., Gulyas, J., Fischer, W., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.121165198 · Cited by 925
Ethologically-based animal models of anxiety disorders.
Lister, R. (1990) · Pharmacology and Therapeutics · doi:10.1016/0163-7258(90)90021-s · Cited by 894
Reyes, T. M., Lewis, K., Perrin, M. H., Kunitake, K. S., Vaughan, J., Arias, C. A., Hogenesch, J. B., Gulyas, J., Rivier, J., Vale, W. W., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.051626398 · Cited by 887
File, S. E. (1980) · Journal of Neuroscience Methods · doi:10.1016/0165-0270(80)90012-6 · Cited by 820
CAN SOCIAL INTERACTION BE USED TO MEASURE ANXIETY?
File, S. E., & Hyde, J. R. G. (1978) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1978.tb07001.x · Cited by 808
Fear-potentiated startle: A neural and pharmacological analysis
Davis, M., Falls, W. A., Campeau, S., & Kim, M. (1993) · Behavioural Brain Research · doi:10.1016/0166-4328(93)90102-v · Cited by 751
Brain oxytocin: A key regulator of emotional and social behaviours in both females and males
Neumann, I. D. (2008) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2008.01726.x · Cited by 743
Shepherd, J. K., Grewal, S. S., Fletcher, A., Bill, D. J., & Dourish, C. T. (1994) · Psychopharmacology · doi:10.1007/bf02244871 · Cited by 739
Zobel, A. W., Nickel, T., Künzel, H. E., Ackl, N., Sonntag, A., Ising, M., & Holsboer, F. (2000) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(00)00016-9 · Cited by 705
Anxiogenic stimuli in the elevated plus-maze
Treit, D., Menard, J., & Royan, C. (1993) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(93)90492-c · Cited by 628
Hökfelt, T. G. M., Broberger, C., Xu, Q., Sergeyev, V., Ubink, R., & Diez, M. (2000) · Neuropharmacology · doi:10.1016/s0028-3908(00)00010-1 · Cited by 607
Beinfeld, M. C., Meyer, D., Eskay, R. L., Jensen, R. T., & Brownstein, M. (1981) · Brain Research · doi:10.1016/0006-8993(81)90031-7 · Cited by 551
Vasopressin: Behavioral roles of an “original” neuropeptide
Caldwell, H. K., Lee, H.-J., Macbeth, A. H., & Young, W. S. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.10.007 · Cited by 504
Hughes, J. W., Boden, P., Costall, B., Domeney, A. M., Kelly, E., Horwell, D. C., Hunter, J. C., Pinnock, R. D., & Woodruff, G. N. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.17.6728 · Cited by 501
Different data from different labs: Lessons from studies of gene–environment interaction
Wahłsten, D., Metten, P., Phillips, T. J., Boehm, S. L., Burkhart‐Kasch, S., Dorow, J. D., Doerksen, S., Downing, C., Fogarty, J., Rodd‐Henricks, K., et al. (2002) · Journal of Neurobiology · doi:10.1002/neu.10173 · Cited by 495
Animal model of depression: Pharmacological sensitivity of a hedonic deficit
Katz, R. J. (1982) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(82)90053-3 · Cited by 480
Griebel, G., Simiand, J., Serradeil-Le Gal, C., Wagnon, J., Pascal, M., Scatton, B., Maffrand, J.-P., & Soubrié, P. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092012099 · Cited by 471
Neumann, Wigger, Torner, Holsboer, & Landgraf (2000) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2000.00442.x · Cited by 452
Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders
Holmes, A., Heilig, M. A., Rupniak, N. M. J., Steckler, T., & Griebel, G. (2003) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2003.09.011 · Cited by 405
Radulovic, J., Rühmann, A., Liepold, T., & Spiess, J. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-12-05016.1999 · Cited by 402
Neumann, I. D., Torner, L., & Wigger, A. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00433-9 · Cited by 402
Heilig, M. A., S�derpalm, B., Engel, J. A., & Widerl�v, E. (1989) · Psychopharmacology · doi:10.1007/bf00441953 · Cited by 390
Holsboer, F., & Ising, M. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.12.032 · Cited by 380
Schulz, D. W., Mansbach, R. S., Sprouse, J. S., Braselton, J. P., Collins, J. L., Corman, M. L., Dunaiskis, A. R., Faraci, S., Schmidt, A. W., Seeger, T., et al. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.19.10477 · Cited by 377
The Flinders sensitive line rats: a genetic animal model of depression
Overstreet, D. H. (1993) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80230-1 · Cited by 369
Guastella, A. J., Howard, A. L., Dadds, M. R., Mitchell, P., & Carson, D. S. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.01.005 · Cited by 366
Neuropeptides: opportunities for drug discovery
Hökfelt, T. G. M., Bartfai, T., & Bloom, F. E. (2003) · The Lancet Neurology · doi:10.1016/s1474-4422(03)00482-4 · Cited by 335
An Anxiolytic Action of Oxytocin is Enhanced by Estrogen in the Mouse
MCCARTHY, M. M., MCDONALD, C. H., BROOKS, P. J., & GOLDMAN, D. (1996) · Physiology & Behavior · doi:10.1016/s0031-9384(96)00212-0 · Cited by 328
Plasma oxytocin levels and anxiety in patients with major depression
Scantamburlo, G., Hansenne, M., Fuchs, S., Pitchot, W., Maréchal, P., Péqueux, C., Ansseau, M., & Legros, J. J. (2007) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2007.01.009 · Cited by 325
Ring, R. H., Malberg, J. E., Potestio, L., Ping, J., Boikess, S., Luo, B., Schechter, L. E., Rizzo, S., Rahman, Z., & Rosenzweig-Lipson, S. (2006) · Psychopharmacology · doi:10.1007/s00213-005-0293-z · Cited by 319
Plasma Levels of Arginine Vasopressin Elevated in Patients with Major Depression
van Londen, L. (1997) · Neuropsychopharmacology · doi:10.1016/s0893-133x(97)00054-7 · Cited by 306
The role of substance P in stress and anxiety responses
Ebner, K., & Singewald, N. (2006) · Amino Acids · doi:10.1007/s00726-006-0335-9 · Cited by 304
The Mouse Defense Test Battery: pharmacological and behavioral assays for anxiety and panic
Blanchard, D. C., Griebel, G., & Blanchard, R. J. (2003) · European Journal of Pharmacology · doi:10.1016/s0014-2999(03)01276-7 · Cited by 295
Keller, M., Montgomery, S., Ball, W., Morrison, M., Snavely, D., Liu, G., Hargreaves, R., Hietala, J., Lines, C., Beebe, K., et al. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.07.013 · Cited by 286
Prenatal stress generates deficits in rat social behavior: Reversal by oxytocin
Lee, P. R., Brady, D. L., Shapiro, R. A., Dorsa, D. M., & Koenig, J. I. (2007) · Brain Research · doi:10.1016/j.brainres.2007.04.042 · Cited by 270
Davis, M. (1979) · Psychopharmacology · doi:10.1007/bf00426027 · Cited by 263
Wigger, A., Sánchez, M. M., Mathys, K. C., Ebner, K., Frank, E., Liu, D., Kresse, A. E., Neumann, I. D., Holsboer, F., Plotsky, P. M., et al. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300290 · Cited by 263
Kramer, M. S., Winokur, A., Kelsey, J. E., Preskorn, S., Rothschild, A. J., Snavely, D. B., Ghosh, K., Ball, W. A., Reines, S. A., Munjack, D. J., et al. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300260 · Cited by 254
Binneman, B., Feltner, D., Kolluri, S., Shi, Y., Qiu, R., & Stiger, T. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.07071199 · Cited by 254
Deak, T., Nguyen, K. T., Ehrlich, A. L., Watkins, L. R., Spencer, R. L., Maier, S. F., Licinio, J., Wong, M.-L., Chrousos, G. P., Webster, E., et al. (1999) · Endocrinology · doi:10.1210/endo.140.1.6415 · Cited by 242
Ebner, K., Rupniak, N. M. J., Saria, A., & Singewald, N. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0400794101 · Cited by 225
Becker, C., Zeau, B., Rivat, C., Blugeot, A., Hamon, M., & Benoliel, J. J. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002097 · Cited by 225
Isolation and structure of hypothalamic MSH release-inhibiting hormone
Nair, R. M. G., Kastin, A. J., & Schally, A. V. (1971) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(71)80026-8 · Cited by 224
Evidence for an involvement of the brain cholecystokinin B receptor in anxiety.
Singh, L., Lewis, A. S., Field, M. J., Hughes, J. W., & Woodruff, G. N. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.4.1130 · Cited by 213
Redrobe, J. P. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00403-1 · Cited by 207
Corticotropin-releasing factor modulates defensive-withdrawal and exploratory behavior in rats.
Takahashi, L. K., Kalin, N. H., Burgt, J. A. V., & Sherman, J. E. (1989) · Behavioral Neuroscience · doi:10.1037//0735-7044.103.3.648 · Cited by 203
Oxytocin acts as an antidepressant in two animal models of depression
Arletti, R., & Bertolini, A. (1987) · Life Sciences · doi:10.1016/0024-3205(87)90600-x · Cited by 203
Social Interaction Deficits Caused by Chronic Phencyclidine Administration are Reversed by Oxytocin
Lee, P. R., Brady, D. L., Shapiro, R. A., Dorsa, D. M., & Koenig, J. I. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300722 · Cited by 199
Broqua, P., Wettstein, J. G., Rocher, M. N., Gauthier-Martin, B., & Junien, J. (1995) · Behavioural Pharmacology · doi:10.1097/00008877-199504000-00001 · Cited by 198
Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats
Slattery, D. A., & Neumann, I. D. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.06.038 · Cited by 195
Antidepressant-like effects of CP-154,526, a selective CRF1 receptor antagonist
Mansbach, R. S., Brooks, E. N., & Chen, Y. L. (1997) · European Journal of Pharmacology · doi:10.1016/s0014-2999(97)00025-3 · Cited by 195
Pharmacological characterization of Endomorphin-1 and Endomorphin-2 in Mouse Brain
Goldberg, I. E., Rossi, G. C., Letchworth, S. R., Mathis, J. P., Ryan‐Moro, J. P., Leventhal, L., Su, W., Emmel, D. W., Bolan, E. A., & Pasternak, G. W. (1998) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37681-5 · Cited by 189
Swanson, C. J., Blackburn, T. P., Zhang, X., Zheng, K., Xu, Q., Hökfelt, T. G. M., Wolinsky, T. D., Konkel, M. J., Chen, H., Zhong, H., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508970102 · Cited by 182
Celis, M. E., Taleisnik, S., & Walter, R. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.7.1428 · Cited by 181
Corticotropin-releasing factor modulates defensive-withdrawal and exploratory behavior in rats.
Takahashi, L. K., Kalin, N. H., Burgt, J. A. V., et al. (1989) · Behavioral Neuroscience · doi:10.1037/0735-7044.103.3.648 · Cited by 175
Septal vasopressin modulates anxiety-related behaviour in rats
Liebsch, G., Wotjak, C. T., Landgraf, R., & Engelmann, M. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(96)13069-x · Cited by 173
Recent advances in the neurobiology of anxiety disorders: Implications for novel therapeutics
Mathew, S. J., Price, R. B., & Charney, D. S. (2008) · American Journal of Medical Genetics Part C Seminars in Medical Genetics · doi:10.1002/ajmg.c.30172 · Cited by 172
Is There a Future for Neuropeptide Receptor Ligands in the Treatment of Anxiety Disorders?
Griebel, G. (1999) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(98)00041-2 · Cited by 171
Windle, R. J., Shanks, N., Lightman, S. L., & Ingram, C. D. (1997) · Endocrinology · doi:10.1210/en.138.7.2829 · Cited by 170
Urocortin, a novel neuropeptide with anxiogenic-like properties
Moreau, J., Kilpatrick, G. J., & Jenck, F. (1997) · Neuroreport · doi:10.1097/00001756-199705060-00027 · Cited by 170
Teixeira, R. M., Santos, A. R. S., Ribeiro, S. J., Calixto, J. Β., Rae, G. A., & de Lima, T. C. M. (1996) · European Journal of Pharmacology · doi:10.1016/0014-2999(96)00390-1 · Cited by 166
The vasopressin system — From antidiuresis to psychopathology
Frank, E., & Landgraf, R. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.11.063 · Cited by 162
Localization of oxytocin receptor messenger ribonucleic acid in the rat brain.
Yoshimura, R., Kiyama, H., Kimura, T., Araki, T., Maeno, H., Tanizawa, O., & Tohyama, M. (1993) · Endocrinology · doi:10.1210/endo.133.3.8396014 · Cited by 161
The Role of CRF in Behavioral Aspects of Stress
Heinrichs, S. C., Menzaghi, F., Pich, E. M., Britton, K. T., & Koob, G. F. (1995) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1995.tb44673.x · Cited by 160
Long-term neuroendocrine and behavioural effects of a single exposure to stress in adult animals
Armario, A., Escorihuela, R. M., & Nadal, R. A. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.04.003 · Cited by 160
The anxiolytic effect of the CRH1 receptor antagonist R121919 depends on innate emotionality in rats
Keck, M. E., Welt, T., Wigger, A., Renner, U., Engelmann, M., Holsboer, F., & Landgraf, R. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2000.01383.x · Cited by 154
Okuyama, S., Chaki, S., Kawashima, N., Suzuki, Y., Ogawa, S., Nakazato, A., Kumagai, T., Okubo, T., & Tomisawa, K. (1999) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)38220-5 · Cited by 152
Galanin – 25 years with a multitalented neuropeptide
Mitsukawa, K., Lü, X., & Bartfai, T. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8153-8 · Cited by 151
The Vogel conflict test: procedural aspects, γ-aminobutyric acid, glutamate and monoamines
Millan, M. J., & Brocco, M. (2003) · European Journal of Pharmacology · doi:10.1016/s0014-2999(03)01275-5 · Cited by 149
Heinrichs, S. C. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00299-3 · Cited by 148
The role of CRH in behavioral responses to stress
Smagin, G. N., Heinrichs, S. C., & Dunn, A. J. (2001) · Peptides · doi:10.1016/s0196-9781(01)00384-9 · Cited by 148
Everts, H. G. J., & Koolhaas, J. M. (1999) · Behavioural Brain Research · doi:10.1016/s0166-4328(98)00004-7 · Cited by 147
Henry, B., Vale, W., & Markou, A. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.1494-06.2006 · Cited by 147
Sajdyk, T. J., Johnson, P. L., Leitermann, R. J., Fitz, S. D., Dietrich, A. D., Morin, M., Gehlert, D. R., Urban, J. H., & Shekhar, A. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.0659-07.2008 · Cited by 147
Neuropeptide Y (NPY) and depression: From animal studies to the human condition
Redrobe, J. P., Dumont, Y., & Quirion, R. (2002) · Life Sciences · doi:10.1016/s0024-3205(02)02159-8 · Cited by 146
Neuropeptide-Y exerts antidepressant-like effects in the forced swim test in rats
Stogner, K. A., & Holmes, P. V. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(99)00800-6 · Cited by 144
Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist
Ring, R. H., Schechter, L. E., Leonard, S. K., Dwyer, J. M., Platt, B. J., Graf, R., Grauer, S. M., Pulicicchio, C. M., Resnick, L., Rahman, Z. U., et al. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2009.07.016 · Cited by 144
Crawley, J. N. (1995) · Regulatory Peptides · doi:10.1016/0167-0115(95)00083-n · Cited by 143
Heinrichs, S. C., Menzaghi, F., Pich, E. M., Baldwin, H. A., Rassnick, S., Britton, K. T., & Koob, G. F. (1994) · Neuropsychopharmacology · doi:10.1038/sj.npp.1380104 · Cited by 143
Valdez, G. R., Inoue, K., Koob, G. F., Rivier, J., Vale, W., & Zorrilla, E. P. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02707-5 · Cited by 143
Beiderbeck, D. I., Neumann, I. D., & Veenema, A. H. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05974.x · Cited by 142
Valdez, G. R., Zorrilla, E. P., Rivier, J., Vale, W., & Koob, G. F. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02971-8 · Cited by 140
Galanin: A Significant Role in Depression?
Weiss, J. M., Bonsall, R. W., Demetrikopoulos, M. K., Emery, M., & West, C. H. K. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb10707.x · Cited by 139
Kunzel, H. E., Zobel, A. W., Nickel, T., Ackl, N., Uhr, M., Sonntag, A., Ising, M., & Holsboer, F. (2003) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(03)00070-0 · Cited by 134
Antagonism of CRF2 receptors produces anxiolytic behavior in animal models of anxiety
Takahashi, L. K., Ho, S. P., Livanov, V., Graciani, N., & Arneric, S. P. (2001) · Brain Research · doi:10.1016/s0006-8993(01)02405-2 · Cited by 132
A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus
Lü, X., Barr, A. M., Kinney, J. W., Sanna, P. P., Conti, B., Behrens, M. M., & Bartfai, T. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408891102 · Cited by 131
Behavioral reactivity to stress
Khoshbouei, H., Cecchi, M., Dove, S., Javors, M. A., & Morilak, D. A. (2002) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00683-9 · Cited by 130
Differential roles for neuropeptide Y Y1 and Y5 receptors in anxiety and sedation
Sørensen, G., Lindberg, C., Wörtwein, G., Bolwig, T. G., & Woldbye, D. P. D. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20200 · Cited by 124
Anxiolytic-like effect of neuropeptide Y (NPY), but not other peptides in an operant conflict test
Heilig, M. A., McLeod, S., Koob, G. K., & Britton, K. T. (1992) · Regulatory Peptides · doi:10.1016/0167-0115(92)90514-u · Cited by 123
Overstreet, D. H. (2002) · Behavior Genetics · doi:10.1023/a:1020262205227 · Cited by 122
Rotzinger, S., & Vaccarino, F. J. (2003) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0322 · Cited by 120
Self-citationVarty, G. B. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(02)00313-5 · Cited by 120
Neuropeptide Y Produces Anxiety Via Y2-Type Receptors
Nakajima, M., Inui, A., Asakawa, A., Momose, K., Ueno, N., Teranishi, A., Baba, S., & Kasuga, M. (1998) · Peptides · doi:10.1016/s0196-9781(97)00298-2 · Cited by 119
A placebo-controlled trial of L-365,260, a CCKB antagonist, in panic disorder
Kramer, M. S., Cutler, N. R., Ballenger, J. C., Patterson, W. M., Mendels, J., Chenault, A., Shrivastava, R. K., Matzura‐Wolfe, D., Lines, C., & Reines, S. A. (1995) · Biological Psychiatry · doi:10.1016/0006-3223(94)00190-e · Cited by 117
The behavioural effects of corticotropin-releasing factor-related peptides in rats
Jones, D. N. C., Kortekaas, R., Slade, P. D., Middlemiss, D. N., & Hagan, J. J. (1998) · Psychopharmacology · doi:10.1007/s002130050654 · Cited by 115
The role of Corticotropin Releasing Factor in Depressive Illness: a Critical Review
Mitchell, A. J. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(97)00059-6 · Cited by 115
Anxiolytic-like action of centrally administered galanin
Bing, O., Møller, C. H., Engel, J. A., Söderpalm, B., & Heilig, M. A. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90846-d · Cited by 114
Antidepressant-like effects of CRF1 receptor antagonist SSR125543 in an animal model of depression
Overstreet, D. H., & Griebel, G. (2004) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.06.035 · Cited by 112
Stemmelin, J., Lukovic, L., Salome, N., & Griebel, G. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300562 · Cited by 112
Burbach, J. P. H., & Lebouille, J. L. M. (1983) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)33011-4 · Cited by 111
Kuteeva, E., Wardi, T., Lundström, L., Sollenberg, U. E., Langel, Ü., Hökfelt, T. G. M., & Ögren, S. O. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301660 · Cited by 110
Gehlert, D. R., Shekhar, A., Morin, S. M., Hipskind, P. A., Zink, C., Gackenheimer, S. L., Shaw, J., Fitz, S. D., & Sajdyk, T. J. (2005) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.12.030 · Cited by 110
Anxiogenic-Like Action of Galanin after Intra-Amygdala Administration in the Rat
Möller, C. (1999) · Neuropsychopharmacology · doi:10.1016/s0893-133x(98)00102-x · Cited by 110
Galanin and Its Receptors in Neurological Disorders
Lundström, L., Elmquist, A., Bartfai, T., & Langel, Ü. (2005) · NeuroMolecular Medicine · doi:10.1385/nmm:7:1-2:157 · Cited by 110
Risbrough, V. B., Hauger, R. L., Pelleymounter, M. A., & Geyer, M. A. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1535-6 · Cited by 107
Anxiolytic-like actions of centrally-administered neuropeptide Y, but not galanin, in C57BL/6J mice
Karlsson, R., Holmes, A., Heilig, M. A., & Crawley, J. N. (2005) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2004.12.009 · Cited by 105
A water lick conflict paradigm using drug experienced rats
Petersen, E. N., & Lassen, J. B. (1981) · Psychopharmacology · doi:10.1007/bf00432430 · Cited by 104
Overstreet, D. H., Keeney, A. J., & Hogg, S. (2004) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.04.010 · Cited by 104
Galanin, Galanin Receptor Subtypes and Depression-Like Behaviour
Kuteeva, E., Hökfelt, T. G. M., Wardi, T., & Ögren, S. O. (2010) · Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions · doi:10.1007/978-3-0346-0228-0_12 · Cited by 102
Melanocyte-Stimulating Hormone-Release Inhibiting Hormone as an Antidepressant
Ehrensing, R. H. (1974) · Archives of General Psychiatry · doi:10.1001/archpsyc.1974.01760070047007 · Cited by 96
Galanin receptors: Involvement in feeding, pain, depression and Alzheimer's disease
Kask, K., Berthold, M., & Bartfai, T. (1997) · Life Sciences · doi:10.1016/s0024-3205(96)00624-8 · Cited by 94
Millan, M. J. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00244-5 · Cited by 94
Britton, K. T., Akwa, Y., Spina, M. G., & Koob, G. F. (2000) · Peptides · doi:10.1016/s0196-9781(99)00169-2 · Cited by 94
Anxiolytic effects of buspirone and gepirone in the fear-potentiated startle paradigm
Kehne, J. H., Cassella, J. V., & Davis, M. (1988) · Psychopharmacology · doi:10.1007/bf00735872 · Cited by 93
Pan, W., & Kastin, A. J. (2007) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.10.008 · Cited by 92
Escape deficits induced by uncontrollable stress: Antagonism by dopamine and norepinephrine agonists
Anisman, H., Suissa, A., & Sklar, L. S. (1980) · Behavioral and Neural Biology · doi:10.1016/s0163-1047(80)93132-5 · Cited by 92
On the role of urocortin 1 in the non-preganglionic Edinger–Westphal nucleus in stress adaptation
Kozicz, T. (2007) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2007.04.005 · Cited by 92
Galanin – 25 years with a multitalented neuropeptide
Kuteeva, E., Hökfelt, T. G. M., Wardi, T., & Ögren, S. O. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8160-9 · Cited by 92
Vasopressin administration modulates anxiety-related behavior in rats
Appenrodt, E., Schnabel, R., & Schwarzberg, H. (1998) · Physiology & Behavior · doi:10.1016/s0031-9384(98)00119-x · Cited by 91
Enkephalin and other peptides reduce passiveness
Kastin, A. J., Scollan, E. L., Ehrensing, R. H., Schally, A. V., & Coy, D. H. (1978) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(78)90051-5 · Cited by 91
Cholecystokinin-2 (CCK2) receptor-mediated anxiety-like behaviors in rats
Wang, H., Wong, P. T. ‐., Spiess, J., & Zhu, Y. Z. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.05.008 · Cited by 89
Salomé, N., Stemmelin, J., Cohen, C., & Griebel, G. (2006) · Psychopharmacology · doi:10.1007/s00213-006-0424-1 · Cited by 89
Khoshbouei, H. (2002) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00424-9 · Cited by 88
Endomorphins have orexigenic and anxiolytic activities in mice
Asakawa, A., Inui, A., Momose, K., Ueno, N., Fujino, M., & Kasuga, M. (1998) · Neuroreport · doi:10.1097/00001756-199807130-00022 · Cited by 87
A comparison of anxiolytic and nonanxiolytic agents in the shock-probe/burying test for anxiolytics
Treit, D. (1990) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(90)90151-7 · Cited by 86
Dose-related biphasic effect of prolyl-leucyl-glycinamide (MIF-I) in depression
Rh, E., & Aj, K. (1978) · American Journal of Psychiatry · doi:10.1176/ajp.135.5.562 · Cited by 86
Distribution of cholecystokinin (CCK) in the rat lower brain stem nuclei
Beinfeld, M. C., & Palkovits, M. (1982) · Brain Research · doi:10.1016/0006-8993(82)90794-6 · Cited by 85
de Groote, L., Peñalva, R. G., Flachskamm, C., Reul, J. M. H. M., & Linthorst, A. C. E. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03164.x · Cited by 84
Teneurin proteins possess a carboxy terminal sequence with neuromodulatory activity
Wang, L., Rotzinger, S., Chawaf, A. A., Elias, C. F., Baršytė-Lovejoy, D., Qian, X., Wang, N.-C., Cristofaro, A. D., Belsham, D. D., Bittencourt, J. C., et al. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.10.019 · Cited by 83
Self-citationZhao, Y., Valdez, G. R., Fekete, É. M., Rivier, J., Vale, W. W., Rice, K. C., Weiss, F., & Zorrilla, E. P. (2007) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.123208 · Cited by 83
Hodgson, R. A., Higgins, G. A., Guthrie, D. H., Lu, S. X., Pond, A. J., Mullins, D. E., Guzzi, M. F., Parker, E. M., & Varty, G. B. (2007) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.12.021 · Cited by 82
Rezayat, M., Roohbakhsh, A., Zarrindast, M.-R., Massoudi, R., & Djahanguiri, B. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.03.002 · Cited by 82
Papp, M., Vassout, A., & Gentsch, C. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(00)00230-8 · Cited by 82
Frankland, P. W., Josselyn, S. A., Bradwejn, J., Vaccarino, F. J., & Yeomans, J. S. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-05-01838.1997 · Cited by 81
Kokare, D. M., Dandekar, M. P., Chopde, C. T., & Subhedar, N. K. (2005) · Brain Research · doi:10.1016/j.brainres.2005.02.038 · Cited by 80
Antidepressant-like activity of corticotropin-releasing factor type-1 receptor antagonists in mice
Nielsen, D. M., Carey, G. J., & Gold, L. H. (2004) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.07.091 · Cited by 80
Substance P is involved in the sensitization of the acoustic startle response by footshocks in rats
Krase, W., Koch, M., & Schnitzler, H. (1994) · Behavioural Brain Research · doi:10.1016/0166-4328(94)90053-1 · Cited by 79
Bacchi, F., Mathé, A. A., Jiménez, P., Stasi, L. P., Arban, R., Gerrard, P. A., & Caberlotto, L. (2006) · Peptides · doi:10.1016/j.peptides.2006.07.020 · Cited by 79
Adams, J. B., Pyke, R. E., Costa, J., Cutler, N. R., Schweizer, E. E., Wilcox, C. S., Wisselink, P., Greiner, M., Pierce, M., & Pande, A. C. (1995) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199512000-00007 · Cited by 79
Shimazaki, T., Iijima, M., & Chaki, S. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.06.032 · Cited by 78
Spiga, F., Lightman, S. L., Shekhar, A., & Lowry, C. A. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.12.051 · Cited by 75
van Megen, H. J. G. M., Westenberg, H. G. M., den Boer, J. A., Slaap, B. R., Radhakishun, F. S., & Pande, A. C. (1997) · Psychopharmacology · doi:10.1007/s002130050186 · Cited by 75
The vasopressin V1b receptor as a therapeutic target in stress-related disorders
Griebel, G., Simiand, J., Stemmelin, J., Gal, C., & Steinberg, R. (2003) · Current Drug Target -CNS & Neurological Disorders · doi:10.2174/1568007033482850 · Cited by 74
‘Anxiolytic’ effect of CCK-antagonists on plus-maze behavior in mice
Rataud, J., Darche, F., Piot, O., Stutzmann, J. M., Böhme, G. A., & Blanchard, J. (1991) · Brain Research · doi:10.1016/0006-8993(91)91139-r · Cited by 73
Vivian, J. A., Barros, H. M. T., Manitiu, A., & Miczek, K. A. (1997) · PubMed · Cited by 71
Characterization of the V1a antagonist, JNJ-17308616, in rodent models of anxiety-like behavior
Bleickardt, C. J., Mullins, D. E., MacSweeney, C. P., Werner, B. J., Pond, A. J., Guzzi, M. F., Martin, F. D. C., Varty, G. B., & Hodgson, R. A. (2009) · Psychopharmacology · doi:10.1007/s00213-008-1354-x · Cited by 71
Vivian, J. A., Barros, H. M. T., Manitiu, A., & Miczek, K. A. (1997) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)36770-9 · Cited by 71
Antidepressant-like effects of neurokinin receptor antagonists in the forced swim test in the rat
Dableh, L. J., Yashpal, K., Rochford, J. M., & Henry, J. L. (2004) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.11.024 · Cited by 70
NKP608, an NK1 receptor antagonist, has an anxiolytic action in the social interaction test in rats
File, S. E. (2000) · Psychopharmacology · doi:10.1007/s002130000513 · Cited by 70
Ögren, S. O., Kuteeva, E., kfelt, T. H., & Kehr, J. (2006) · CNS Drugs · doi:10.2165/00023210-200620080-00003 · Cited by 68
Barr, A. M., Kinney, J. W., Hill, M. N., Lü, X., Biros, S. M., REBEK, J. J., & Bartfai, T. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.06.033 · Cited by 68
Kask, A., Rägo, L., & Harro, J. (1998) · Regulatory Peptides · doi:10.1016/s0167-0115(98)00076-7 · Cited by 67
Ishida, H., Shirayama, Y., Iwata, M., Katayama, S., Yamamoto, A., Kawahara, R., & Nakagome, K. (2007) · Hippocampus · doi:10.1002/hipo.20264 · Cited by 67
Galanin – 25 years with a multitalented neuropeptide
Hökfelt, T. G. M., & Tatemoto, K. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8152-9 · Cited by 65
Qian, X., Baršytė-Lovejoy, D., Wang, L., Chewpoy, B., Gautam, N., Chawaf, A. A., & Lovejoy, D. A. (2004) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2004.02.007 · Cited by 64
Self-citationFendt, M., Bürki, H., Imobersteg, S., Lingenhöhl, K., McAllister, K. H., Orain, D., Uzunov, D. P., & Chaperon, F. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1610-8 · Cited by 61
Yamano, M., Yuki, H., Yasuda, S., & Miyata, K. (2000) · PubMed · Cited by 58
Ballard, T. M., Sänger, S., & Higgins, G. A. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)00724-5 · Cited by 58
Overstreet, D. H., & Griebel, G. (2005) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2005.07.021 · Cited by 58
Galanin enhances and a galanin antagonist attenuates depression-like behaviour in the rat
Kuteeva, E., Wardi, T., Hökfelt, T. G. M., & Ögren, S. O. (2006) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2006.03.003 · Cited by 57
Lovejoy, D. A., Chawaf, A. A., & Cadinouche, M. Z. A. (2006) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2006.01.012 · Cited by 57
Self-citationAnxiolytic-like activity of the non-selective galanin receptor agonist, galnon
Rajarao, S. J. R., Platt, B. J., Rizzo, S. J. S., Lin, Q., Bender, C. N., Nieuwenhuijsen, B. W., Ring, R. H., Schechter, L. E., Rosenzweig-Lipson, S. J., & Beyer, C. E. (2007) · Neuropeptides · doi:10.1016/j.npep.2007.05.001 · Cited by 56
Hernando, F., Fuentes, J., Roques, B. P., & Ruiz‐Gayo, M. (1994) · European Journal of Pharmacology · doi:10.1016/0014-2999(94)90115-5 · Cited by 55
Mathé, A. A., Husum, H., Khoury, A. E., Jiménez-Vasquez, P. A., Gruber, S. H. M., Wörtwein, G., Nikisch, G., Baumann, P., Ågren, H., Andersson, W., et al. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.05.016 · Cited by 55
Chawaf, A. A., Amant, K. S., Belsham, D. D., & Lovejoy, D. A. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.09.062 · Cited by 54
Self-citationPlacebo-controlled trial of the CCK-B antagonist, CI-988, in panic disorder
Pande, A. C., Greiner, M., Adams, J. B., Lydiard, R. B., & Pierce, M. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00090-6 · Cited by 54
Fear-enhanced acoustic startle is not attenuated by acute or chronic imipramine treatment in rats
Cassella, J. V., & Davis, M. (1985) · Psychopharmacology · doi:10.1007/bf00432707 · Cited by 52
Vasopressin Antagonists as Anxiolytics and Antidepressants: Recent Developments
Simon, N. G., Guillon, C., Fabio, K. M., Heindel, N. D., Lu, S., Miller, M., Ferris, C. F., Brownstein, M., Garippa, C., & KOPPEL, G. A. (2008) · Recent Patents on CNS Drug Discovery · doi:10.2174/157488908784534586 · Cited by 52
Antidepressant-Like Effect of Endomorphin-1 and Endomorphin-2 in Mice
Fichna, J., Janecka, A. E., Piestrzeniewicz, M. K., Costentin, J., & do-Rego, J.-C. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301149 · Cited by 51
Chenu, F., Guiard, B. P., Bourin, M., & Gardier, A. M. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.05.011 · Cited by 51
Tanaka, M., & Telegdy, G. (2007) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2007.08.009 · Cited by 50
Corticotropin-releasing factor type-1 receptor antagonists: The next class of antidepressants?
Nielsen, D. M. (2005) · Life Sciences · doi:10.1016/j.lfs.2005.06.003 · Cited by 50
Neurohypophyseal hormones and brain neurochemistry
Versteeg, D. H. G. (1982) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(82)90071-7 · Cited by 50
Chawaf, A. A., Xu, K. H., Tan, L. A., Vaccarino, F. J., Lovejoy, D. A., & Rotzinger, S. (2007) · Peptides · doi:10.1016/j.peptides.2007.05.014 · Cited by 49
Self-citationFrom MIF-1 to endomorphin: The Tyr-MIF-1 family of peptides
Pan, W., & Kastin, A. J. (2007) · Peptides · doi:10.1016/j.peptides.2007.10.006 · Cited by 47
Goyal, S. N., Kokare, D. M., Ct, C., & Subhedar, N. K. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.09.004 · Cited by 46
Klenerová, V., Krejčı́, I., Sida, P., Hlinak, Z., & Hynie, S. (2009) · PubMed · Cited by 46
Induction of NGFI-B mRNA following contextual fear conditioning and its blockade by diazepam
Malkani, S., & Rosen, J. B. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00130-3 · Cited by 42
Rapid clinical effectiveness of MIF-I in the treatment of major depressive illness
VELDE, C. D. V. D. (1983) · Peptides · doi:10.1016/0196-9781(83)90136-5 · Cited by 42
Wilson, J., Watson, W. P., & Little, H. J. (1998) · Psychopharmacology · doi:10.1007/s002130050601 · Cited by 41
Improvement in major depression after low subcutaneous doses of MIF-1
Ehrensing, R. H., Kastin, A. J., Wurzlow, G. F., Michell, G. F., & Mebane, A. H. (1994) · Journal of Affective Disorders · doi:10.1016/0165-0327(94)90098-1 · Cited by 41
Research works printed but not linked: 1
- Deak, 1999, The impact of the nonpeptide corticotropin-releasing hormone antagonist antalarmin on behavioral and endocrine responses to stress, Endocrinology, 140, 79, 10.1210/en.140.1.79 · DOI · Paper page
Cited by
Sorted by citations
The Effects of Psychological Stress on Depression
Yang, L., Zhao, Y., Wang, Y., Liu, L., Zhang, X., Li, B., & Cui, R. (2015) · Current Neuropharmacology · doi:10.2174/1570159x1304150831150507 · Cited by 589
Breaking the loop: Oxytocin as a potential treatment for drug addiction
McGregor, I. S., & Bowen, M. T. (2012) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.12.001 · Cited by 268
Cochran, D. M., Fallon, D., Hill, M., & Frazier, J. A. (2013) · Harvard Review of Psychiatry · doi:10.1097/hrp.0b013e3182a75b7d · Cited by 267
Stress, Endocrine Physiology and Pathophysiology -- Endotext
DeGroot, L. J., Chrousos, G. P., Dungan, K., Grossman, A. B., Jm, H., Koch, C., Korbonits, M., McLachlan, R., New, M., Purnell, J. Q., et al. (2000) · Europe PMC (PubMed Central) · Cited by 260
Comparative Analyses of Zebrafish Anxiety-Like Behavior Using Conflict-Based Novelty Tests
Kysil, E. V., Мешалкина, Д. А., Frick, E. E., Echevarria, D. J., Rosemberg, D. B., Maximino, C., Lima, M. G., de Abreu, M. S., Giacomini, A. C. V. V., Barcellos, L. J. G., et al. (2017) · Zebrafish · doi:10.1089/zeb.2016.1415 · Cited by 277
Metadata
- Authors
- Rotzinger, S., Lovejoy, D. A., & Tan, L. A.
- Affiliations
- University of Toronto (CA)
- Corresponding author
- Tan, Laura A.
- Venue
- Peptides
- Publisher
- Elsevier BV
- Published
- 2010-04
- Volume
- 31
- Issue
- 4
- Pages
- 736-756
- ISSN
- 0196-9781 (ISSN-L)
- OpenAlex
- W2087834131
- Cited by
- 211
- References
- 245
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 8 · 2023: 5 · 2022: 10 · 2021: 6 · 2020: 6 · 2019: 8 · 2018: 9 · 2017: 14 · 2016: 10 · 2015: 12 · 2014: 21 · 2013: 24 · 2012: 27
- FWCI
- 1.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Peptides (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research (FRN 72027622)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- neuropeptides, depression, anxiety, mood disorders, corticotropin-releasing factor, urocortin, neuropeptide Y, vasopressin, oxytocin, cholecystokinin, galanin, substance P, antidepressant screening, rodent models, therapeutic target
- MeSH terms
- Animals, Anxiety, Arginine Vasopressin, Behavior, Animal, Cholecystokinin, Corticotropin-Releasing Hormone, Depression, Disease Models, Animal, Humans, MSH Release-Inhibiting Hormone, Neuropeptide Y, Neuropeptides, Neuropsychological Tests, Oxytocin, Social Behavior, Galanin, Urocortins
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review