Modeling sleep alterations in Parkinson's disease: how close are we to valid translational animal models?
Open accessAbstract
Parkinson disease is one of the neurodegenerative diseases that benefited the most from the use of non-human models. Consequently, significant advances have been made in the symptomatic treatments of the motor aspects of the disease. Unfortunately, this translational success has been tempered by the recognition of the debilitating aspect of multiple non-motor symptoms of the illness. Alterations of the sleep/wakefulness behavior experienced as insomnia, excessive daytime sleepiness, sleep/wake cycle fragmentation and REM sleep behavior disorder are among the non-motor symptoms that predate motor alterations and inevitably worsen over disease progression. The absence of adequate humanized animal models with the perfect phenocopy of these sleep alterations contribute undoubtedly to the lack of efficient therapies for these non-motor complications. In the context of developing efficient translational therapies, we provide an overview of the strengths and limitations of the various currently available models to replicate sleep alterations of Parkinson's disease. Our investigation reveals that although these models replicate dopaminergic deficiency and related parkinsonism, they rarely display a combination of sleep fragmentation and excessive daytime sleepiness and never REM sleep behavior disorder. In this light, we critically discuss the construct, face and predictive validities of both rodent and non-human primate animals to model the main sleep abnormalities experienced by patients with PD. We conclude by highlighting the need of integrating a network-based perspective in our modeling approach of such complex syndrome in order to celebrate valid translational models.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The text we found for this paper looks like another document, so the self-check wasn’t run.
Cites
Principles and Practice of Sleep Medicine
Kryger, M. H., Roth, T. G., & Dement, W. C. (2011) · Elsevier eBooks · doi:10.1016/c2009-0-59875-3 · Cited by 5,118 · see citing works
Brain stem reticular formation and activation of the EEG
Moruzzi, G., & Magoun, H. W. (1949) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(49)90219-9 · Cited by 4,307 · see citing works
Non-motor symptoms of Parkinson's disease: diagnosis and management
Chaudhuri, K. R., Healy, D. G., & Schapira, A. H. (2006) · The Lancet Neurology · doi:10.1016/s1474-4422(06)70373-8 · Cited by 2,807 · see citing works
Hypothalamic regulation of sleep and circadian rhythms
Saper, C. B., Scammell, T. E., & Lu, J. (2005) · Nature · doi:10.1038/nature04284 · Cited by 2,804 · see citing works
Parkinson, J. (2002) · Journal of Neuropsychiatry · doi:10.1176/jnp.14.2.223 · Cited by 2,684 · see citing works
Luk, K. C., Kehm, V., Carroll, J., Zhang, B., O’Brien, P., Trojanowski, J. Q., & Lee, V. M.-Y. (2012) · Science · doi:10.1126/science.1227157 · Cited by 2,563 · see citing works
Tononi, G., & Cirelli, C. (2014) · Neuron · doi:10.1016/j.neuron.2013.12.025 · Cited by 2,356 · see citing works
Burns, R. S., Chiueh, C. C., Markey, S. P., Ebert, M. H., Jacobowitz, D. M., & Kopin, I. J. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.14.4546 · Cited by 2,149 · see citing works
Structural and molecular interrogation of intact biological systems
Chung, K., Wallace, J., Kim, S.-Y., Kalyanasundaram, S., Andalman, A. S., Davidson, T. J., Mirzabekov, J. J., Zalocusky, K. A., Mattis, J., Denisin, A. K., et al. (2013) · Nature · doi:10.1038/nature12107 · Cited by 2,008 · see citing works
Li, J.-Y., Englund, E., Holton, J. L., Soulet, D., Hagell, P., Lees, A. J., Lashley, T., Quinn, N. P., Rehncrona, S., Björklund, A., et al. (2008) · Nature Medicine · doi:10.1038/nm1746 · Cited by 1,845 · see citing works
Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment
Chaudhuri, К. R., & Schapira, A. H. V. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70068-7 · Cited by 1,739 · see citing works
Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
Kordower, J. H., Chu, Y., Hauser, R. A., Freeman, T. B., & Olanow, C. W. (2008) · Nature Medicine · doi:10.1038/nm1747 · Cited by 1,722 · see citing works
Optical Deconstruction of Parkinsonian Neural Circuitry
Gradinaru, V., Mogri, M., Thompson, K. R., Henderson, J. M., & Deisseroth, K. A. (2009) · Science · doi:10.1126/science.1167093 · Cited by 1,536 · see citing works
Sleep Homeostasis and Models of Sleep Regulation
Borb, A. A., & Achermann, P. (1999) · Journal of Biological Rhythms · doi:10.1177/074873099129000894 · Cited by 1,503 · see citing works
Control of sleep and wakefulness
Brown, R. E., Basheer, R., McKenna, J. T., Strecker, R. E., & McCarley, R. W. (2012) · Physiological Reviews · doi:10.1152/physrev.00032.2011 · Cited by 1,477 · see citing works
Barone, P., Antonini, A., Colosimo, C., Marconi, R., Morgante, L., Avarello, T. P., Bottacchi, E., Cannas, A., Ceravolo, G., Ceravolo, R., et al. (2009) · Movement Disorders · doi:10.1002/mds.22643 · Cited by 1,445 · see citing works
Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis
Susaki, E. A., Tainaka, K., Perrin, D., Kishino, F., Tawara, T., Watanabe, T. M., Yokoyama, C., Onoe, H., Eguchi, M., Yamaguchi, S., et al. (2014) · Cell · doi:10.1016/j.cell.2014.03.042 · Cited by 1,301 · see citing works
The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness
Sakurai, T. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2092 · Cited by 1,276 · see citing works
Sleep Cycle Oscillation: Reciprocal Discharge by Two Brainstem Neuronal Groups
Hobson, J. A., McCarley, R. W., & Wyzinski, P. (1975) · Science · doi:10.1126/science.1094539 · Cited by 1,238 · see citing works
A putative flip–flop switch for control of REM sleep
Lu, J., Sherman, D. L., Devor, M. G., & Saper, C. B. (2006) · Nature · doi:10.1038/nature04767 · Cited by 1,219 · see citing works
Chronic Behavioral Disorders of Human REM Sleep: A New Category of Parasomnia
Schenck, C. H., Bundlie, S. R., Ettinger, M. G., & Mahowald, M. W. (1986) · SLEEP · doi:10.1093/sleep/9.2.293 · Cited by 1,156 · see citing works
Luk, K. C., Kehm, V. M., Zhang, B., O’Brien, P., Trojanowski, J. Q., & Lee, V. M. ‐. (2012) · The Journal of Experimental Medicine · doi:10.1084/jem.20112457 · Cited by 1,087 · see citing works
Zarow, C., Lyness, S. A., Mortimer, J. A., & Chui, H. C. (2003) · Archives of Neurology · doi:10.1001/archneur.60.3.337 · Cited by 1,003 · see citing works
The Neurobiology of Sleep: Genetics, cellular physiology and subcortical networks
Pace-Schott, E. F., & Hobson, J. A. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn895 · Cited by 937 · see citing works
Brain Imaging in Alzheimer Disease
Johnson, K. A., Fox, N. C., Sperling, R. A., & Klunk, W. E. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006213 · Cited by 875 · see citing works
Prion-like spreading of pathological α-synuclein in brain
Masuda-Suzukake, M., Nonaka, T., Hosokawa, M., Oikawa, T., Arai, T., Akiyama, H., Mann, D. M. A., & Hasegawa, M. (2013) · Brain · doi:10.1093/brain/awt037 · Cited by 867 · see citing works
Parkinson's Disease and Parkinsonism: Neuropathology
Dickson, D. W. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a009258 · Cited by 847 · see citing works
The cognitive neuroscience of sleep: neuronal systems, consciousness and learning
Hobson, J. A., & Pace-Schott, E. F. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn915 · Cited by 835 · see citing works
Genetic Animal Models of Parkinson's Disease
Dawson, T. M., Ko, H. S., & Dawson, V. L. (2010) · Neuron · doi:10.1016/j.neuron.2010.04.034 · Cited by 825 · see citing works
Duty, S., & Jenner, P. G. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01426.x · Cited by 758 · see citing works
Optogenetic investigation of neural circuits underlying brain disease in animal models
Tye, K. M., & Deisseroth, K. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3171 · Cited by 745 · see citing works
Edgar, D. M., Dement, W., & Fuller, C. A. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-03-01065.1993 · Cited by 685 · see citing works
Pathology of Parkinson’s disease
Jellinger, K. A. (1991) · Molecular and Chemical Neuropathology · doi:10.1007/bf03159935 · Cited by 682 · see citing works
Chaudhuri, К. R. (2002) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.73.6.629 · Cited by 676 · see citing works
Experimental models of Parkinson's disease
Beal, M. F. (2001) · Nature reviews. Neuroscience · doi:10.1038/35072550 · Cited by 634 · see citing works
Principles and Practice of Sleep Medicine
Stafford, R. S. (2001) · JAMA · doi:10.1001/jama.285.8.1074 · Cited by 612 · see citing works
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
Corti, O., Lesage, S., & Brice, A. (2011) · Physiological Reviews · doi:10.1152/physrev.00022.2010 · Cited by 610 · see citing works
Sleep as a fundamental property of neuronal assemblies
Krueger, J. M., Rector, D. M., Roy, S., Van Dongen, H. P. A., Belenky, G., & Panksepp, J. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2521 · Cited by 596 · see citing works
Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease
Sulzer, D. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.03.009 · Cited by 583 · see citing works
Hypocretin (orexin) cell loss in Parkinson's disease
Thannickal, T. C., Lai, Y.-Y., & Siegel, J. M. (2007) · Brain · doi:10.1093/brain/awm097 · Cited by 566 · see citing works
Hirsch, É. C., Graybiel, A. M., Duyckaerts, C. J., & Javoy-Agid, F. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.16.5976 · Cited by 554 · see citing works
The Homeostatic Regulation of Sleep Need Is under Genetic Control
Franken, P., Chollet, D., & Tafti, M. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-08-02610.2001 · Cited by 551 · see citing works
Parkinson’s disease and sleepiness
Arnulf, I., Konofal, É., Merino-Andreu, M., Houéto, J., Mesnage, V., Welter, M., Lacomblez, L., Golmard, J., Derenne, J., & Agid, Y. (2002) · Neurology · doi:10.1212/wnl.58.7.1019 · Cited by 512 · see citing works
Achermann, P., Dijk, D.-J., Brunner, D. P., & Borbély, A. A. (1993) · Brain Research Bulletin · doi:10.1016/0361-9230(93)90016-5 · Cited by 470 · see citing works
Sleep viewed as a state of adaptive inactivity
Siegel, J. M. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2697 · Cited by 468 · see citing works
Hypocretin (orexin) loss in Parkinson's disease
Fronczek, R., Overeem, S., Lee, S. Y. Y., Hegeman, I. M., van Pelt, J., van Duinen, S. G., Lammers, G. J., & Swaab, D. F. (2007) · Brain · doi:10.1093/brain/awm090 · Cited by 463 · see citing works
A clinico-pathological study of subtypes in Parkinson's disease
Selikhova, M. V., Williams, D. R., Kempster, P. A., Holton, J. L., Révész, T., & Lees, A. J. (2009) · Brain · doi:10.1093/brain/awp234 · Cited by 462 · see citing works
Identification of Wake-Active Dopaminergic Neurons in the Ventral Periaqueductal Gray Matter
Lu, J., Jhou, T. C., & Saper, C. B. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.2244-05.2006 · Cited by 458 · see citing works
Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates
Collier, T. J., Kanaan, N. M., & Kordower, J. H. (2011) · Nature reviews. Neuroscience · doi:10.1038/nrn3039 · Cited by 453 · see citing works
An optogenetic toolbox designed for primates
Diester, I., Kaufman, M. T., Mogri, M., Pashaie, R., Goo, W., Yizhar, O., Ramakrishnan, C., Deisseroth, K., & Shenoy, K. V. (2011) · Nature Neuroscience · doi:10.1038/nn.2749 · Cited by 443 · see citing works
Excessive daytime sleepiness and subsequent development of Parkinson disease
Abbott, R. D., Ross, G. W., White, L. R., Tanner, C. M., Masaki, K., Nelson, J. S., Curb, J. D., & Petrovitch, H. (2005) · Neurology · doi:10.1212/01.wnl.0000183056.89590.0d · Cited by 439 · see citing works
Recent Advances in the Genetics of Parkinson's Disease
Martin, I., Dawson, V. L., & Dawson, T. M. (2011) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-082410-101440 · Cited by 438 · see citing works
Treatment of motor and non-motor features of Parkinson's disease with deep brain stimulation
Fasano, A. A., Daniele, A., & Albanese, A. (2012) · The Lancet Neurology · doi:10.1016/s1474-4422(12)70049-2 · Cited by 436 · see citing works
Neuropathology underlying clinical variability in patients with synucleinopathies
Halliday, G. M., Holton, J. L., Révész, T., & Dickson, D. W. (2011) · Acta Neuropathologica · doi:10.1007/s00401-011-0852-9 · Cited by 426 · see citing works
Chronic insomnia and activity of the stress system
Vgontzas, A. N., Tsigos, C., Bixler, E. O., Stratakis, C. A., Zachman, K., Kales, A., Vela-Bueno, A., & Chrousos, G. P. (1998) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(97)00302-4 · Cited by 401 · see citing works
Strassman, A. M., Highstein, S. M., & McCREA, R. A. (1986) · The Journal of Comparative Neurology · doi:10.1002/cne.902490303 · Cited by 397 · see citing works
REM sleep behavior disorder and degenerative dementia
Boeve, B. F., Silber, M. H., Ferman, T. J., Kokmen, E., Smith, G. E., Ivnik, R. J., Parisi, J. E., Olson, E. J., & Petersen, R. C. (1998) · Neurology · doi:10.1212/wnl.51.2.363 · Cited by 392 · see citing works
Prion-like acceleration of a synucleinopathy in a transgenic mouse model
Mougenot, A.-L. J., Nicot, S., Bencsik, A. A., Morignat, E., Verchère, J., Lakhdar, L., Legastelois, S., & Baron, T. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.06.022 · Cited by 375 · see citing works
Sleep-related violence, injury, and REM sleep behavior disorder in Parkinson's disease
Comella, C. L., Nardine, T. M., Diederich, N. J., & Stebbins, G. T. (1998) · Neurology · doi:10.1212/wnl.51.2.526 · Cited by 372 · see citing works
Dijk, D., Beersma, D. G. M., & Daan, S. (1987) · Journal of Biological Rhythms · doi:10.1177/074873048700200304 · Cited by 369 · see citing works
Gao, H.-M., Zhang, F., Zhou, H., Kam, W., Wilson, B., & Hong, J.-S. (2011) · Environmental Health Perspectives · doi:10.1289/ehp.1003013 · Cited by 355 · see citing works
Guilding, C., & Piggins, H. D. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05581.x · Cited by 348 · see citing works
Self-citationRiluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: The NNIPPS Study
Bensimon, G., Ludolph, A., Agid, Y., Vidailhet, M., Payan, C., & Leigh, P. N. (2008) · Brain · doi:10.1093/brain/awn291 · Cited by 345 · see citing works
The genetics and neuropathology of Parkinson’s disease
Houlden, H., & Singleton, A. (2012) · Acta Neuropathologica · doi:10.1007/s00401-012-1013-5 · Cited by 320 · see citing works
Sleep EEG in the rat as a function of prior waking
Tobler, I., & Borbély, A. A. (1986) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(86)90044-1 · Cited by 319 · see citing works
Hippocampal theta rhythm: A tag for short‐term memory
Vertes, R. P. (2005) · Hippocampus · doi:10.1002/hipo.20118 · Cited by 319 · see citing works
Dopaminergic Control of Sleep–Wake States
Dzirasa, K., Ribeiro, S. T. G., Costa, R. M., Santos, L. M., Lin, S., Grosmark, A., Sotnikova, T. D., Gainetdinov, R. R., Caron, M. G., & Nicolelis, M. A. L. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1767-06.2006 · Cited by 313 · see citing works
Huber, R., Deboer, T., & Tobler, I. (2000) · Brain Research · doi:10.1016/s0006-8993(99)02248-9 · Cited by 313 · see citing works
Self-citationProgression of Parkinson's disease in the clinical phase: potential markers
Maetzler, W., Liepelt, I., & Berg, D. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70291-1 · Cited by 307 · see citing works
The progression of pathology in Parkinson's disease
Halliday, G. M., & McCann, H. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05118.x · Cited by 298 · see citing works
Datta, S., & MacLean, R. R. (2007) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.02.004 · Cited by 296 · see citing works
Evaluation of animal models of neurobehavioral disorders
van der Staay, F. J., Arndt, S. S., & Nordquist, R. E. (2009) · Behavioral and Brain Functions · doi:10.1186/1744-9081-5-11 · Cited by 294 · see citing works
Jones, B. E., Harper, S. T., & Halaris, A. E. (1977) · Brain Research · doi:10.1016/0006-8993(77)90948-9 · Cited by 279 · see citing works
Taylor, T. N., Caudle, W. M., Shepherd, K. R., Noorian, A. R., Jackson, C. R., Iuvone, P. M., Weinshenker, D., Greene, J. G., & Miller, G. W. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1495-09.2009 · Cited by 278 · see citing works
Practice Parameter: Treatment of nonmotor symptoms of Parkinson disease [RETIRED]
Zesiewicz, T., Sullivan, K. L., Arnulf, I., Chaudhuri, К. R., Morgan, J. C., Gronseth, G., Miyasaki, J. M., Iverson, D. J., & Weiner, W. J. (2010) · Neurology · doi:10.1212/wnl.0b013e3181d55f24 · Cited by 273 · see citing works
Loss of circadian rhythm in sleep-wakefulness cycle in the rat by suprachiasmatic nucleus lesions
Ibuka, N., & Kawamura, H. (1975) · Brain Research · doi:10.1016/0006-8993(75)90574-0 · Cited by 271 · see citing works
Toxin Models of Mitochondrial Dysfunction in Parkinson's Disease
Martinez, T. N., & Greenamyre, J. T. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4033 · Cited by 270 · see citing works
Monitoring and Staging Human Sleep
Carskadon, M. A., & Rechtschaffen, A. (2005) · Elsevier eBooks · doi:10.1016/b0-72-160797-7/50123-3 · Cited by 270 · see citing works
GBA-associated PD presents with nonmotor characteristics
Brockmann, K., Srulijes, K., Hauser, A. ‐., Schulte, C., Csóti, I., Gasser, T., & Berg, D. (2011) · Neurology · doi:10.1212/wnl.0b013e318225ab77 · Cited by 267 · see citing works
Shouse, M. N., & Siegel, J. M. (1992) · Brain Research · doi:10.1016/0006-8993(92)90508-7 · Cited by 250 · see citing works
Circadian and sleep disorders in Parkinson's disease
Videnović, A., & Golombek, D. A. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2012.08.018 · Cited by 247 · see citing works
Biomarkers in Parkinson’s disease (recent update)
Sharma, S. K., Moon, C. S., Khogali, A., Haidous, A., Chabenne, A., Ojo, C., Jelebinkov, M., Kurdi, Y., & Ebadi, M. (2013) · Neurochemistry International · doi:10.1016/j.neuint.2013.06.005 · Cited by 242 · see citing works
Bulbo-thalamic neurons related to thalamocortical activation processes during paradoxical sleep
Steriade, M., Sakai, K., & Jouvet, M. (1984) · Experimental Brain Research · doi:10.1007/bf00235472 · Cited by 241 · see citing works
Puschmann, A. (2013) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2013.01.020 · Cited by 238 · see citing works
Datta, S., & Siwek, D. F. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10405 · Cited by 235 · see citing works
Developing Therapeutic Antibodies for Neurodegenerative Disease
Yu, Y. J., & Watts, R. J. (2013) · Neurotherapeutics · doi:10.1007/s13311-013-0187-4 · Cited by 227 · see citing works
Role of cat pontine burst neurons in generation of saccadic eye movements.
Kaneko, C. R. S., Evinger, C. L., & Fuchs, A. F. (1981) · Journal of Neurophysiology · doi:10.1152/jn.1981.46.3.387 · Cited by 225 · see citing works
Mammalian Diurnality: Some Facts and Gaps
Smale, L., Lee, T. M., & Núñez, A. A. (2003) · Journal of Biological Rhythms · doi:10.1177/0748730403256651 · Cited by 221 · see citing works
Dynamics of the sleep EEG after an early evening nap: experimental data and simulations
Werth, E., Dijk, D., Achermann, P., & Borbély, A. A. (1996) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1996.271.3.r501 · Cited by 220 · see citing works
Contributions of non-human primates to neuroscience research
Capitanio, J. P., & Emborg, M. E. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60489-4 · Cited by 214 · see citing works
Forno, L. S., DeLanney, L. E., Irwin, I., & Langston, J. W. (1993) · PubMed · Cited by 207 · see citing works
Idiopathic REM sleep behaviour disorder in the development of Parkinson's disease
Boeve, B. F. (2013) · The Lancet Neurology · doi:10.1016/s1474-4422(13)70054-1 · Cited by 201 · see citing works
Basal ganglia control of sleep–wake behavior and cortical activation
Qiu, M., Vetrivelan, R., Fuller, P. M., & Lu, J. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.07062.x · Cited by 196 · see citing works
Anxiety in Parkinson’s disease: A critical review of experimental and clinical studies
Prediger, R. D. S., Matheus, F. C., Schwarzbold, M. L., Lima, M. M. S., & Vital, M. A. B. F. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.08.039 · Cited by 190 · see citing works
Modelling of Parkinson's disease in mice
Chesselet, M., & Richter, F. (2011) · The Lancet Neurology · doi:10.1016/s1474-4422(11)70227-7 · Cited by 190 · see citing works
Steriade, M., Oakson, G., & Ropert, N. (1982) · Experimental Brain Research · doi:10.1007/bf00238096 · Cited by 185 · see citing works
Breakdown in REM sleep circuitry underlies REM sleep behavior disorder
Peever, J. H., Luppi, P., & Montplaisir, J. Y. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2014.02.009 · Cited by 181 · see citing works
Improvement of sleep architecture in PD with subthalamic nucleus stimulation
Arnulf, I., Bejjani, B.-P. W., Garma, L., Bonnet, A. M., Houéto, J., Damier, P., Derenne, J., & Agid, Y. (2000) · Neurology · doi:10.1212/wnl.55.11.1732 · Cited by 181 · see citing works
Sleep homeostasis in the rat: Simulation of the time course of EEG slow-wave activity
Franken, P., Tobler, I., & Borbély, A. A. (1991) · Neuroscience Letters · doi:10.1016/0304-3940(91)90382-4 · Cited by 180 · see citing works
Animal models of Parkinson's disease: Limits and relevance to neuroprotection studies
Bézard, E., Yue, Z., Kirik, D., & Spillantini, M. G. (2012) · Movement Disorders · doi:10.1002/mds.25108 · Cited by 176 · see citing works
Iranzo, Á. (2002) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.72.5.661 · Cited by 174 · see citing works
Synaptic plasticity in sleep: learning, homeostasis and disease
Wang, G., Grone, B., Colas, D., Appelbaum, L., & Mourrain, P. (2011) · Trends in Neurosciences · doi:10.1016/j.tins.2011.07.005 · Cited by 172 · see citing works
Circadian and Homeostatic Regulation of Structural Synaptic Plasticity in Hypocretin Neurons
Appelbaum, L., Wang, G. X., Yokogawa, T., Skariah, G. M., Smith, S. J., Mourrain, P., & Mignot, E. J.-M. (2010) · Neuron · doi:10.1016/j.neuron.2010.09.006 · Cited by 172 · see citing works
Novel designer receptors to probe GPCR signaling and physiology
Wess, J., Nakajima, K., & Jain, S. (2013) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2013.04.006 · Cited by 158 · see citing works
Animal models of the non-motor features of Parkinson's disease
McDowell, K. A., & Chesselet, M. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.12.040 · Cited by 158 · see citing works
Cellular Basis of Pontine Ponto-geniculo-occipital Wave Generation and Modulation
Datta, S. (1997) · Cellular and Molecular Neurobiology · doi:10.1023/a:1026398402985 · Cited by 156 · see citing works
Localization of pontine PGO wave generation sites and their anatomical projections in the rat
Datta, S., Siwek, D. F., Patterson, E. H., & Cipolloni, P. B. (1998) · Synapse · doi:10.1002/(sici)1098-2396(199812)30:4 · Cited by 156 · see citing works
Krakow, B. J., Melendrez, D. C., Johnston, L. G., Warner, T. D., Clark, J. O., Pacheco, M. B., PEDERSEN, B., Koss, M. P., Hollifield, M. A., & Schrader, R. (2002) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-200207000-00004 · Cited by 155 · see citing works
Sleep disorders in Parkinson's disease: The contribution of the MPTP non-human primate model
Barraud, Q., Lambrecq, V., Forni, C., McGuire, S., Hill, M. P., Bioulac, B. H., Balzamo, E., Bézard, E., Tison, F., & Ghorayeb, I. (2009) · Experimental Neurology · doi:10.1016/j.expneurol.2009.07.019 · Cited by 150 · see citing works
Paths from Pesticides to Parkinson's
Kamel, F. (2013) · Science · doi:10.1126/science.1243619 · Cited by 141 · see citing works
Progressive sleep ‘destructuring’ in Parkinson's disease. A polysomnographic study in 46 patients
Diederich, N. J., Vaillant, M., MANCUSO, G., LYEN, P., & Tiete, J. (2005) · Sleep Medicine · doi:10.1016/j.sleep.2005.03.011 · Cited by 140 · see citing works
Sleep disturbances in patients with parkinsonism
Cock, V. C. D., Vidailhet, M., & Arnulf, I. (2008) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0775 · Cited by 139 · see citing works
The rotenone model of Parkinson's disease
Perier, C., Bové, J., Vila, M., & Przedborski, S. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00144-9 · Cited by 131 · see citing works
Engineering Approaches to Illuminating Brain Structure and Dynamics
Deisseroth, K. A., & Schnitzer, M. J. (2013) · Neuron · doi:10.1016/j.neuron.2013.10.032 · Cited by 119 · see citing works
Neuronal activity in the peribrachial area: Relationship to behavioral state control
Datta, S. (1995) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(94)00043-z · Cited by 115 · see citing works
The Role of the Substantia Nigra Pars Compacta in Regulating Sleep Patterns in Rats
Lima, M. M. S., Andersen, M. L., Reksidler, A. B., Vital, M. A. B. F., & Tufik, S. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000513 · Cited by 112 · see citing works
Nawaratne, V., Leach, K., Suratman, N., Loiacono, R. E., Felder, C. C., Armbruster, B. N., Roth, B. L., Sexton, P. M., & Christopoulos, A. (2008) · Molecular Pharmacology · doi:10.1124/mol.108.049353 · Cited by 112 · see citing works
Parkinson's disease: a model dilemma
Beal, M. F. (2010) · Nature · doi:10.1038/466s8a · Cited by 110 · see citing works
Management of Motor and Non-Motor Symptoms in Parkinson’s Disease
Sprenger, F., & Poewe, W. H. (2013) · CNS Drugs · doi:10.1007/s40263-013-0053-2 · Cited by 99 · see citing works
From Animal Models to Model Animals
Insel, T. R. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.10.001 · Cited by 98 · see citing works
Sleepiness in Parkinson's disease
Arnulf, I., & Leu‐Semenescu, S. (2009) · Parkinsonism & Related Disorders · doi:10.1016/s1353-8020(09)70792-8 · Cited by 98 · see citing works
Opp, M. R. (1995) · Advances in Neuroimmunology · doi:10.1016/0960-5428(95)00004-l · Cited by 96 · see citing works
Imaging of compensatory mechanisms in Parkinson's disease
Appel‐Cresswell, S., de la Fuente‐Fernández, R., Galley, S., & McKeown, M. J. (2010) · Current Opinion in Neurology · doi:10.1097/wco.0b013e32833b6019 · Cited by 92 · see citing works
Rapid eye movement sleep behavior disorder in parkinsonism with parkin mutations
Kumru, H., Santamaría, J., TOLOSA, E. S., Valldeoriola, F., Muñoz, E., Martı́, M. J., & Iranzo, Á. (2004) · Annals of Neurology · doi:10.1002/ana.20272 · Cited by 90 · see citing works
The role of neuroplasticity in dopaminergic therapy for Parkinson disease
Zhuang, X., Mazzoni, P., & Kang, U. J. (2013) · Nature Reviews Neurology · doi:10.1038/nrneurol.2013.57 · Cited by 90 · see citing works
Nigrostriatal Dopamine Acting on Globus Pallidus Regulates Sleep
Qiu, M., Yao, Q.-L., Vetrivelan, R., Chen, M. C., & Lu, J. (2014) · Cerebral Cortex · doi:10.1093/cercor/bhu241 · Cited by 89 · see citing works
Boulet, S., Mounayar, S., Poupard, A., Bertrand, A., Jan, C., Pessiglione, M., Hirsch, É. C., Feuerstein, C., François, C., Féger, J., et al. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3465-08.2008 · Cited by 89 · see citing works
No Lewy pathology in monkeys with over 10 years of severe MPTP Parkinsonism
Halliday, G. M., Herrero, M. T., Murphy, K., McCann, H., Ros‐Bernal, F., Barcia, C., Mori, H., Blesa, F. J., & Obeso, J. A. (2009) · Movement Disorders · doi:10.1002/mds.22481 · Cited by 86 · see citing works
Relationship between sleep disorders and other non-motor symptoms in Parkinson's disease
Kurtis, M. M., Rodríguez‐Blázquez, C., & Martínez‐Martín, P. (2013) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2013.07.026 · Cited by 85 · see citing works
REM Sleep Behavior Disorder in the Marmoset MPTP Model of Early Parkinson Disease
Verhave, P. S., Jongsma, M. J., van den Berg, R. M., Vis, J. C., Vanwersch, R. A. P., Smit, A. B., Someren, E. J. W. V., & Philippens, I. H. C. H. M. (2011) · SLEEP · doi:10.5665/sleep.1174 · Cited by 85 · see citing works
Disturbed sleep in P arkinson's disease: anatomical and pathological correlates
Kalaitzakis, M. E., Gentleman, S., & Pearce, R. K. B. (2013) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12024 · Cited by 84 · see citing works
Sudden Uncontrollable Somnolence and Medication Use in Parkinson Disease
Avorn, J., Schneeweiß, S., Sudarsky, L. R., et al. (2005) · Archives of Neurology · doi:10.1001/archneur.62.8.1242 · Cited by 84 · see citing works
Progress and Prospects for Genetic Modification of Nonhuman Primate Models in Biomedical Research
Chan, A. W. S. (2013) · ILAR Journal · doi:10.1093/ilar/ilt035 · Cited by 79 · see citing works
Optogenetics in primates: a shining future?
Gerits, A., & Vanduffel, W. (2013) · Trends in Genetics · doi:10.1016/j.tig.2013.03.004 · Cited by 78 · see citing works
Stages of sleep pathology in spinocerebellar ataxia type 2 (SCA2)
Tuin, I., Voss, U., Kang, J., Kessler, K. R., Rüb, U., Nolte, D., Lochmüller, H., Tinschert, S., Claus, D., Krakow, K., et al. (2006) · Neurology · doi:10.1212/01.wnl.0000247054.90322.14 · Cited by 78 · see citing works
Validating Animal Models for Preclinical Research: A Scientific and Ethical Discussion
Varga, O., Hansen, A. K., Sandøe, P., & Olsson, I. A. S. (2010) · Alternatives to Laboratory Animals · doi:10.1177/026119291003800309 · Cited by 74 · see citing works
The pathology roadmap in Parkinson disease
Surmeier, D. J., & Sulzer, D. (2013) · Prion · doi:10.4161/pri.23582 · Cited by 74 · see citing works
Serotonergic sprouting in primate MTP-induced hemiparkinsonism
Gaspar, P., Febvret, A., & Colombo, J. A. (1993) · Experimental Brain Research · doi:10.1007/bf00230443 · Cited by 74 · see citing works
Behavioral and Electrophysiological Correlates of Sleep and Sleep Homeostasis
Deboer, T. (2013) · Current topics in behavioral neurosciences · doi:10.1007/7854_2013_248 · Cited by 73 · see citing works
Self-citationFifel, K., Vezoli, J., Dzahini, K., Claustrat, B., Leviel, V., Kennedy, H., Procyk, E., Dkhissi‐Benyahya, O., Gronfier, C., & Cooper, H. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086240 · Cited by 72 · see citing works
Self-citationDissimilarity of slow-wave activity enhancement by torpor and sleep deprivation in a hibernator
Strijkstra, A. M., & Daan, S. (1998) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1998.275.4.r1110 · Cited by 70 · see citing works
Hsieh, K., Robinson, E. L., & Fuller, C. A. (2008) · SLEEP · doi:10.5665/sleep/31.9.1239 · Cited by 67 · see citing works
Aging of Intrinsic Circadian Rhythms and Sleep in a Diurnal Nonhuman Primate, Macaca mulatta
Zhdanova, I. V., Masuda, K., Quasarano-Kourkoulis, C., Rosene, D. L., Killiany, R., & Wang, S. (2011) · Journal of Biological Rhythms · doi:10.1177/0748730410395849 · Cited by 63 · see citing works
Sleep Dysfunction and EEG Alterations in Mice Overexpressing Alpha-Synuclein
McDowell, K. A., Shin, D., Roos, K. P., & Chesselet, M. (2018) · Journal of Parkinson s Disease · doi:10.3233/jpd-140374 · Cited by 62 · see citing works
SLOW ORTHOSTATIC TREMOR IN MULTIPLE SCLEROSIS
Ruiz, P. G. G., Ayerbe, J., Bader, B., Danek, A., Sainz, M. J., Cabo, I., & Frech, F. (2009) · Movement Disorders · doi:10.1002/mds.22629 · Cited by 61 · see citing works
Nocturnal sleep structure and temperature slope in MPTP treated monkeys
Almirall, H., Pigarev, I. N., de la Calzada, M. D., Pigareva, M. L., Herrero, M. T., & Sagalés, T. (1999) · Journal of Neural Transmission · doi:10.1007/s007020050228 · Cited by 61 · see citing works
Brody, H. (2013) · Nature · doi:10.1038/502s81a · Cited by 61 · see citing works
Vigilance states in a parkinsonian model, the MPTP mouse
Monaca, C. C., Laloux, C., Jacquesson, J., Gelé, P., Maréchal, X., Bordet, R., Destée, A., & Derambure, P. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03694.x · Cited by 60 · see citing works
Micallef, J., Rey, M., Eusébio, A., et al. (2008) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2008.03310.x · Cited by 60 · see citing works
Risk of Obstructive Sleep Apnea in Parkinson’s Disease: A Meta-Analysis
Zeng, J., Wei, M., Li, T., Chen, W., Feng, Y., Shi, R., Song, Y., Zheng, W., & Ma, W. (2013) · PLoS ONE · doi:10.1371/journal.pone.0082091 · Cited by 60 · see citing works
Association between dopaminergic medications and nocturnal sleep in early-stage Parkinson's disease
Chahine, L. M., Daley, J. T., Horn, S. S., Duda, J. E., Colcher, A., Hurtig, H. I., Cantor, C., & Dahodwala, N. A. (2013) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2013.05.009 · Cited by 59 · see citing works
Engeln, M., Deurwaerdère, P. D., Li, Q., Bézard, E., & Fernagut, P. (2014) · Cerebral Cortex · doi:10.1093/cercor/bhu076 · Cited by 58 · see citing works
Interleukin-1β Mediates Sleep Alteration in Rats With Rotenone-Induced Parkinsonism
Yi, P.-L., Tsai, C., Lu, M., Liu, H.-J., Chen, Y.-C., & Chang, F. (2007) · SLEEP · doi:10.1093/sleep/30.4.413 · Cited by 58 · see citing works
Sleep disorders in Parkinson’s disease: a narrative review of the literature
Raggi, A., Bella, R., Pennisi, G., Neri, W., & Ferri, R. (2013) · Reviews in the Neurosciences · doi:10.1515/revneuro-2013-0002 · Cited by 57 · see citing works
Chronic in vivo multi-circuit neurophysiological recordings in mice
Dzirasa, K., Fuentes, R., Kumar, S., Potes, J. M., & Nicolelis, M. A. L. (2010) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2010.11.014 · Cited by 57 · see citing works
Deboer, T., & Tobler, I. (2003) · SLEEP · doi:10.1093/sleep/26.5.567 · Cited by 57 · see citing works
Self-citationCognitive dysfunction and depression in Parkinson’s disease: what can be learned from rodent models?
Lindgren, H. S., & Dunnett, S. B. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08162.x · Cited by 56 · see citing works
Belaïd, H., Adrien, J., Laffrat, E., Tandé, D., Karachi, C., Grabli, D., Arnulf, I., Clark, S. D., Drouot, X., Hirsch, É. C., et al. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0181-14.2014 · Cited by 56 · see citing works
Circadian modulation of sleep in rodents
Yasenkov, R., & Deboer, T. (2012) · Progress in brain research · doi:10.1016/b978-0-444-59427-3.00012-5 · Cited by 55 · see citing works
Self-citationInsomnia following hypocretin2-saporin lesions of the substantia nigra
Gerashchenko, D., Blanco‐Centurion, C., Miller, J. D., & Shiromani, P. J. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.08.088 · Cited by 54 · see citing works
Fulceri, F., Biagioni, F., Ferrucci, M., Lazzeri, G., Bartalucci, A., Galli, V., Ruggieri, S. A., Paparelli, A., & Fornai, F. (2006) · Brain Research · doi:10.1016/j.brainres.2006.12.030 · Cited by 54 · see citing works
Role of corticotropin-releasing hormone in stressor-induced alterations of sleep in rat
Chang, F., & Opp, M. R. (2002) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00758.2001 · Cited by 54 · see citing works
Peng, J., Oo, M. L., & Andersen, J. K. (2010) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2010.07036.x · Cited by 53 · see citing works
Quantitative descriptions of generalized arousal, an elementary function of the vertebrate brain
Quinkert, A. W., Vimal, V., Weil, Z. M., Reeke, G. N., Schiff, N. D., Banavar, J. R., & Pfaff, D. W. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1101894108 · Cited by 52 · see citing works
Limousin, N., Konofal, É., Karroum, E. G., Lohmann, E., Theodorou, I. D., Dürr, A., & Arnulf, I. (2009) · Movement Disorders · doi:10.1002/mds.22711 · Cited by 49 · see citing works
Linking restless legs syndrome with Parkinson's disease: clinical, imaging and genetic evidence
Peeraully, T., & Tan, E. (2012) · Translational Neurodegeneration · doi:10.1186/2047-9158-1-6 · Cited by 47 · see citing works
Mesolimbic dopaminergic system is involved in diurnal blood pressure regulation
Sakata, M., Séi, H., Toida, K., Fujihara, H., Urushihara, R., & Morita, Y. (2002) · Brain Research · doi:10.1016/s0006-8993(01)03402-3 · Cited by 46 · see citing works
Sleep disturbances in the rotenone animal model of Parkinson disease
García‐García, F., Ponce, S., Brown, R. A., Cussen, V. A., & Krueger, J. M. (2005) · Brain Research · doi:10.1016/j.brainres.2005.02.036 · Cited by 45 · see citing works
Polygraphic evidence against a critical role of the raphe nuclei in sleep in the rat
Mouret, J., & Coindet, J. (1980) · Brain Research · doi:10.1016/0006-8993(80)90975-0 · Cited by 45 · see citing works
D1 receptor agonist improves sleep–wake parameters in experimental parkinsonism
Hyacinthe, C., Barraud, Q., Tison, F., Bézard, E., & Ghorayeb, I. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.10.029 · Cited by 44 · see citing works
MPTP-treated mice: long-lasting loss of nigral TH-ir neurons but not paradoxical sleep alterations
Laloux, C., Derambure, P., Kreisler, A., Houdayer, E., Bruéziëre, S., Bordet, R., Destée, A., & Monaca, C. C. (2008) · Experimental Brain Research · doi:10.1007/s00221-008-1268-1 · Cited by 43 · see citing works
Gomez-Gallego, M., Fernández‐Villalba, E., Fernández-Barreiro, A., & Herrero, M. T. (2006) · Journal of Neural Transmission · doi:10.1007/s00702-006-0547-x · Cited by 42 · see citing works
Shan, L., Liu, C., Balesar, R. A., et al. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.01.004 · Cited by 41 · see citing works
Effect of dopaminergic substances on sleep/wakefulness in saline – and MPTP-treated mice
LALOUX, C., DERAMBURE, P., HOUDAYER, E., JACQUESSON, J., BORDET, R., DESTÉE, A., & MONACA, C. (2008) · Journal of Sleep Research · doi:10.1111/j.1365-2869.2008.00625.x · Cited by 40 · see citing works
Nocturia and overnight polysomnography in Parkinson disease
Vaughan, C. P., Juncos, J. L., Trotti, L. M., et al. (2013) · Neurourology and Urodynamics · doi:10.1002/nau.22365 · Cited by 38 · see citing works
Fujishiro, H., Imamura, A., Lin, W.-L., Uchikado, H., Mark, M. H., Golbe, L. I., Markopoulou, K., Wszołek, Z. K., & Dickson, D. W. (2013) · Europe PMC (PubMed Central) · Cited by 37 · see citing works
Parkinson’s disease: an update on pathogenesis and treatment
Foltynie, T., & Kahan, J. (2013) · Journal of Neurology · doi:10.1007/s00415-013-6915-1 · Cited by 37 · see citing works
Subclinical signs in LRRK2 mutation carriers
Johansen, K. K., White, L. R., Farrer, M. J., & Aasly, J. O. (2011) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2011.04.014 · Cited by 37 · see citing works
Bouyer, J. J., Dedet, L., Debray, O., & Rougeul, A. (1978) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(78)90123-2 · Cited by 35 · see citing works
A novel effect of MPTP: the selective suppression of paradoxical sleep in cats
Pungor, K., Papp, M. I., Kékesi, K. A., & Juhász, G. D. (1990) · Brain Research · doi:10.1016/0006-8993(90)90880-k · Cited by 34 · see citing works
Sleep alterations in an environmental neurotoxin-induced model of parkinsonism
McDowell, K. A., Hadjimarkou, M. M., Viechweg, S. S., et al. (2010) · Experimental Neurology · doi:10.1016/j.expneurol.2010.08.005 · Cited by 33 · see citing works
Verhave, P. S., Jongsma, M. J., van den Berg, R. M., Vanwersch, R. A. P., Smit, A. B., & Philippens, I. H. C. H. M. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.11.016 · Cited by 33 · see citing works
Nonhuman primates: laboratory animals of choice for neurophysiologic studies of sleep.
Balzamo, E., Santucci, Seri, B., et al. (1977) · PubMed · Cited by 33 · see citing works
Parkinson's disease molecular and therapeutic insights from model systems
Nass, R., & Przedborski, S. (2008) · Cited by 33 · see citing works
The immobilization response in rhesus monkey: A behavioral and electroencephalographic study
Holcombe, V., Sterman, M. B., Goodman, S. J., et al. (1979) · Experimental Neurology · doi:10.1016/0014-4886(79)90136-5 · Cited by 29 · see citing works
Thakkar, M. M., Strecker, R. E., & McCarley, R. W. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02914-1 · Cited by 29 · see citing works
Fifel, K., Dkhissi‐Benyahya, O., & Cooper, H. M. (2013) · Chronobiology International · doi:10.3109/07420528.2012.762011 · Cited by 28 · see citing works
Self-citationAbnormal sleep architecture is an early feature in the E46K familial synucleinopathy
Zarranz, J. J., Fernández‐Bedoya, A., Lambarri, I., et al. (2005) · Movement Disorders · doi:10.1002/mds.20581 · Cited by 27 · see citing works
Technologies of sleep research
Deboer, T. (2007) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-6533-0 · Cited by 27 · see citing works
Self-citationTanaka, M., Yamaguchi, E., Takahashi, M., Hashimura, K., Shibata, T., Nakamura, W., & Nakamura, T. J. (2012) · Neuroscience Research · doi:10.1016/j.neures.2012.09.005 · Cited by 26 · see citing works
Sleep quality in a family with hereditary parkinsonism (PARK6)
Tuin, I., Voss, U., Kessler, K. R., et al. (2007) · Sleep Medicine · doi:10.1016/j.sleep.2007.07.004 · Cited by 23 · see citing works
Pfeffer, M., Plenzig, S., Gispert, S., Wada, K., Korf, H., & von Gall, C. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2010.02.019 · Cited by 22 · see citing works
OPTOGENETICS: BACKGROUND AND CONCEPTS FOR NEUROSURGERY
Lin, S.-C., Deisseroth, K. A., & Henderson, J. M. (2011) · Neurosurgery · doi:10.1227/neu.0b013e318224688e · Cited by 18 · see citing works
Sleep does not enhance the recovery of deprived eye responses in developing visual cortex
Dadvand, L., Stryker, M. P., & Frank, M. G. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.029 · Cited by 17 · see citing works
Bensaid, M., Tandé, D., Fabre, V., et al. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12761 · Cited by 16 · see citing works
Hormonal response to restraint in rhesus monkeys
Gauquelin‐Koch, G., Blanquie, J., Viso, M., Florence, G., Milhaud, C., & Gharib, C. (1996) · Journal of Medical Primatology · doi:10.1111/j.1600-0684.1996.tb00034.x · Cited by 10 · see citing works
Driver‐Dunckley, E. D., & Adler, C. H. (2012) · Neurologic Clinics · doi:10.1016/j.ncl.2012.08.019 · Cited by 10 · see citing works
From bench to bed: putative animal models of REM sleep behavior disorder (RBD)
Krenzer, M., Lu, J., Mayer, G., et al. (2013) · Journal of Neural Transmission · doi:10.1007/s00702-012-0965-x · Cited by 9 · see citing works
Role of postural status in the nocturnal hemodynamic patterns of nonhuman primates
Engel, B. T., Talan, M. I., & Chew, P. H. (1993) · Journal of Applied Physiology · doi:10.1152/jappl.1993.74.4.1684 · Cited by 9 · see citing works
Pungor, K., Hajnal, A. S., K�kesi, K. A., et al. (1993) · Experimental Brain Research · doi:10.1007/bf00227140 · Cited by 8 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Circadian disruption and sleep disorders in neurodegeneration
Shen, Y., Lv, Q.-K., Xie, W.-Y., Gong, S.-Y., Zhuang, S., Liu, J.-Y., Mao, C.-J., & Liu, C.-F. (2023) · Translational Neurodegeneration · doi:10.1186/s40035-023-00340-6 · Cited by 171 · see citing works
Circadian dysregulation in Parkinson's disease
Videnovic, A., & Golombek, D. (2017) · Neurobiology of Sleep and Circadian Rhythms · doi:10.1016/j.nbscr.2016.11.001 · Cited by 63 · see citing works
- Authors
- Fifel, K., Piggins, H., & Deboer, T.
- Affiliations
- Leiden University Medical Center (NL)
- University of Manchester (GB)
- Corresponding author
- Fifel, Karim
- Venue
- Sleep Medicine Reviews
- Publisher
- Elsevier BV
- Published
- 2016-02
- Volume
- 25
- Pages
- 95-111
- ISSN
- 1087-0792 (ISSN-L)
- OpenAlex
- W2008887903
- Cited by
- 30
- References
- 202
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 5 · 2022: 3 · 2021: 2 · 2020: 4 · 2019: 4 · 2018: 3 · 2017: 3 · 2016: 3
- FWCI
- 0.40
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- Sleep Medicine Reviews (publishedVersion)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion, other-oa)
- Bristol Research (University of Bristol) (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Leiden Repository (Leiden University) (submittedVersion)
- Explore Bristol Research (submittedVersion)
- Funders
- FONDATION FYSSEN
- Topics
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- Parkinson's disease, sleep disorders, animal models, translational validity, non-motor symptoms, insomnia, excessive daytime sleepiness, sleep fragmentation, REM sleep behavior disorder, dopaminergic deficiency, rodent models, non-human primates, construct validity, face validity, predictive validity, network modeling
- MeSH terms
- Animals, Humans, Parkinson Disease, Sleep Wake Disorders, Disease Progression, Models, Animal, Translational Research, Biomedical
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
