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Cited by 189Smoking Behavior and CessationSubstance Abuse Treatment and OutcomesPrenatal Substance Exposure Effects

Profiles in discouragement: Two studies of variability in the time course of smoking withdrawal symptoms.

Piasecki, Thomas M., Fiore, Michael C., Baker, Timothy B.·1998·Journal of Abnormal Psychology
DOI 10.1037/0021-843x.107.2.238
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Abstract

Research has suggested that the time course of the smoking withdrawal syndrome is fairly invariant across smokers and that smoking withdrawal symptoms are weakly related to relapse. Withdrawal data from 2 clinical trials of the nicotine patch were analyzed to evaluate these characterizations. In both studies, patients were clustered according to the shapes of their withdrawal profiles across 8 weeks of treatment. In each study, 3 clusters with distinct temporal patterns of withdrawal symptomatology emerged. Clusters included both abstinent and lapsing patients, and patch dose was unrelated to cluster membership. Patients with "atypical" patterns of smoking withdrawal (e.g., late symptomatic elevations) were more likely to relapse than patients who showed a gradual elimination of withdrawal. Withdrawal shape, duration, and severity all contributed significantly to the prediction of relapse. Measures of negative affect closely tracked withdrawal symptoms over time within clusters. Topics for future smoking withdrawal research are discussed.

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Crossref · 10.1037/0021-843x.107.2.238

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  • Withdrawal duration and severity predict relapse in abstinent human smokers.

    “Indeed, withdrawal duration and severity predict relapse in abstinent human smokers (Piasecki et al. 1998(Piasecki et al. , 2000(Piasecki et al. , 2003)).”

    From Mechanisms of Nicotine Addiction (2021) · cites this paper as Piasecki et al. 1998

  • In EMA studies, the severity of negative affect and craving are highly predictive of smoking lapse and relapse during abstinence.

    “In studies using Ecological Momentary Assessment (EMA) to measure real-time data in the natural environment, the severity of NA and craving are highly predictive of smoking lapse and relapse during abstinence (McCarthy, Piasecki, Fiore, & Baker, 2006; Piasecki et al., 2000; Piasecki, Fiore, & Baker, 1998; Piper, Loh, Smith, Japuntich, & Baker, 2011; Shiffman, 2005; Shiffman et al., 1997, 2007).”

    From Modeling naturalistic craving, withdrawal, and affect during early nicotine abstinence: A pilot ecological momentary assessment study. (2015) · cites this paper as Piasecki, Fiore, & Baker, 1998

  • Recent studies show that in the context of fine-grained analyses withdrawal indeed can predict relapse.

    “in the context of fine-grained analyses withdrawal indeed can predict relapse [64,65].”

    From Relapse prevention for addictive behaviors (2011) · cites this paper as [65]

  • Nicotine withdrawal symptoms are a primary reason smokers fail to quit and must be alleviated to prevent early relapse.

    “The symptoms associated with nicotine withdrawal are a primary deterrent to cessation and they need to be quelled to avoid early relapse.”

    From Mechanistic insights into nicotine withdrawal (2011) · cites this paper as [26]

  • Symptoms of greater intensity, positive slope and variability predict relapse to smoking, and symptoms of craving and negative affect are the most likely to be associated with relapse.

    “Symptoms of greater intensity, positive slope and variability have been observed to predict relapse to smoking (45, 46) and symptoms of craving and negative affect were the most likely to be associated with relapse (47, 48).”

    From Tobacco addiction (2008) · cites this paper as [45]

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Authors
Piasecki, T. M., Fiore, M. C., & Baker, T. B.
Affiliations
University of Wisconsin–Madison (US)
ORCID
Venue
Journal of Abnormal Psychology
Publisher
American Psychological Association (APA)
Published
1998-05
Volume
107
Issue
2
Pages
238-251
ISSN
  • 0021-843X (ISSN-L)
  • 1939-1846
DOI
10.1037/0021-843x.107.2.238
OpenAlex
W1968910627
Cited by
189
References
69
Citations by year
2025: 1 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 1 · 2020: 6 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 9 · 2015: 4 · 2014: 10 · 2013: 7 · 2012: 9
FWCI
2.11
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Abnormal Psychology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r01da007580-04)
  • National Institute on Drug Abuse (R01-DA07580-03)
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
Keywords
smoking withdrawal symptoms, nicotine patch, recurrence prediction, nicotine dependence, negative affect, smoking cessation, nicotine replacement therapy
MeSH terms
Administration, Cutaneous, Adult, Dose-Response Relationship, Drug, Double-Blind Method, Female, Humans, Male, Middle Aged, Nicotine, Recurrence, Smoking, Substance Withdrawal Syndrome, Smoking Cessation

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