Integrative genomics viewer

A map of human genome variation from population-scale sequencing.

The 1000 Genomes Project Consortium (2010) · Nature · doi:10.1038/nature09534 · Cited by 7,877

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

The Cancer Genome Atlas Research Network (2008) · Nature · doi:10.1038/nature07385 · Cited by 7,735

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

Verhaak, R. G. W., Hoadley, K. A., Purdom, E., Wang, V., Qi, Y., Wilkerson, M. D., Miller, C. R., Ding, L., Golub, T., Mesirov, J. P., et al. (2010) · Cancer Cell · doi:10.1016/j.ccr.2009.12.020 · Cited by 7,575

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

Guttman, M., Amit, I., Garber, M., French, C., Lin, M. F., Feldser, D., Huarte, M., Zuk, O., Carey, B. W., Cassady, J. P., et al. (2009) · Nature · doi:10.1038/nature07672 · Cited by 4,098

Artemis: sequence visualization and annotation

Rutherford, K. M., Parkhill, J., Crook, J., Horsnell, T., Rice, P., Rajandream, M., & Barrell, B. (2000) · Bioinform. · doi:10.1093/bioinformatics/16.10.944 · Cited by 3,295

The ENCODE (ENCyclopedia Of DNA Elements) Project

(2004) · Science · doi:10.1126/science.1105136 · Cited by 2,390

Systematic determination of patterns of gene expression during Drosophila embryogenesis

Tomančák, P., Beaton, A., Weiszmann, R., Kwan, E., Shu, S., Lewis, S., Richards, S., Ashburner, M., Hartenstein, V., Celniker, S., et al. (2002) · Genome biology · doi:10.1186/gb-2002-3-12-research0088 · Cited by 725

Tablet-next generation sequence assembly visualization.

Milne, I., Bayer, M., Cardle, L., Shaw, P., Stephen, G., Wright, F., & Marshall, D. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btp666 · Cited by 666

The Integrated Genome Browser: free software for distribution and exploration of genome-scale datasets

Nicol, J. W., Helt, G. A., Blanchard, S. G., Raja, A. N., & Loraine, A. E. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp472 · Cited by 623

Integrative analysis of the melanoma transcriptome

Berger, M. F., Levin, J. Z., Vijayendran, K., Sivachenko, A., Adiconis, X., Maguire, J., Johnson, L. A., Robinson, J., Verhaak, R. G., Sougnez, C., et al. (2010) · Genome Research · doi:10.1101/gr.103697.109 · Cited by 305

In vivo reprogramming drives Kras-induced cancer development

Shibata, H., Komura, S., Yamada, Y., Sankoda, N., Tanaka, A., Ukai, T., Kabata, M., Sakurai, S., Kuze, B., Woltjen, K., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-04449-5 · Cited by 76

Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence

Olan, I., Parry, A. J., Schoenfelder, S., Narita, M., Ito, Y., Chan, A. S. L., Slater, G. S. C., Bihary, D., Bando, M., Shirahige, K., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-19878-4 · Cited by 76

iPSC Modeling of RBM20-Deficient DCM Identifies Upregulation of RBM20 as a Therapeutic Strategy

Briganti, F., Sun, H., Wei, W., Wu, J., Zhu, C., Liss, M., Karakikes, I., Rego, S., Cipriano, A., Snyder, M., et al. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108117 · Cited by 68

Human and Insect Cell-Produced Recombinant Adeno-Associated Viruses Show Differences in Genome Heterogeneity

Tran, N. T., Lecomte, E., Saleun, S., Namkung, S., Robin, C., Weber, K., Devine, E., Blouin, V., Adjali, O., Ayuso, E., et al. (2022) · Human Gene Therapy · doi:10.1089/hum.2022.050 · Cited by 74

High prevalence of focal and multi-focal somatic genetic variants in the human brain

Keogh, M. J., Wei, W., Aryaman, J., Walker, L., van den Ameele, J., Coxhead, J., Wilson, I., Bashton, M., Beck, J., West, J., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-06331-w · Cited by 74

Cabazitaxel versus abiraterone or enzalutamide in poor prognosis metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase II trial

Annala, M., Fu, S., Bacon, J. V. W., Sipola, J., Iqbal, N., Ferrario, C., Ong, M., Wadhwa, D., Hotte, S. J., Lo, G., et al. (2021) · Annals of Oncology · doi:10.1016/j.annonc.2021.03.205 · Cited by 73

Subpallial Enhancer Transgenic Lines: a Data and Tool Resource to Study Transcriptional Regulation of GABAergic Cell Fate

Silberberg, S. N., Taher, L., Lindtner, S., Sandberg, M., Nord, A. S., Vogt, D., Mckinsey, G. L., Hoch, R., Pattabiraman, K., Zhang, D., et al. (2016) · Neuron · doi:10.1016/j.neuron.2016.09.027 · Cited by 62

Androgen receptor uses relaxed response element stringency for selective chromatin binding and transcriptional regulation in vivo

Sahu, B., Pihlajamaa, P., Dubois, V., Kerkhofs, S., Claessens, F., & Jänne, O. A. (2014) · Nucleic Acids Research · doi:10.1093/nar/gkt1401 · Cited by 66

Histone monoubiquitination by Clock-Bmal1 complex marks Per1 and Per2 genes for circadian feedback

Tamayo, A. G., Duong, H. A., Robles, M. S., Mann, M., & Weitz, C. J. (2015) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.3076 · Cited by 60

Neoantigen-specific immunity in low mutation burden colorectal cancers of the consensus molecular subtype 4

van den Bulk, J., Verdegaal, E. M. E., Ruano, D., Ijsselsteijn, M. E., Visser, M., van der Breggen, R., Duhen, T., van der Ploeg, M., de Vries, N. L., Oosting, J., et al. (2019) · Genome Medicine · doi:10.1186/s13073-019-0697-8 · Cited by 63

Antifungal Tolerance and Resistance Emerge at Distinct Drug Concentrations and Rely upon Different Aneuploid Chromosomes

Yang, F., Scopel, E. F. C., Li, H., Sun, L.-L., Kawar, N., Cao, Y.-B., Jiang, Y.-Y., & Berman, J. (2023) · mBio · doi:10.1128/mbio.00227-23 · Cited by 62

ARID1A facilitates KRAS signaling-regulated enhancer activity in an AP1-dependent manner in colorectal cancer cells

Sen, M., Wang, X., Hamdan, F. H., Rapp, J., Eggert, J., Kosinsky, R. L., Wegwitz, F., Kutschat, A. P., Younesi, F. S., Gaedcke, J., et al. (2019) · Clinical Epigenetics · doi:10.1186/s13148-019-0690-5 · Cited by 61

Profiling DNA break sites and transcriptional changes in response to contextual fear learning

Stott, R. T., Kritsky, O., & Tsai, L.-H. (2021) · PLOS ONE · doi:10.1371/journal.pone.0249691 · Cited by 62

The Exosome Component Rrp6 Is Required for RNA Polymerase II Termination at Specific Targets of the Nrd1-Nab3 Pathway

Fox, M. J., Gao, H., Smith-Kinnaman, W. R., Liu, Y., & Mosley, A. L. (2015) · PLOS Genetics · doi:10.1371/journal.pgen.1004999 · Cited by 61

Vitamin B12 is a limiting factor for induced cellular plasticity and tissue repair

Kovatcheva, M., Melendez, E., Chondronasiou, D., Pietrocola, F., Bernad, R., Caballe, A., Junza, A., Capellades, J., Holguín-Horcajo, A., Prats, N., et al. (2023) · Nature Metabolism · doi:10.1038/s42255-023-00916-6 · Cited by 58

Combined low-pass whole genome and targeted sequencing in liquid biopsies for pediatric solid tumors

Christodoulou, E., Yellapantula, V., O’Halloran, K., Xu, L., Berry, J. L., Cotter, J. A., Zdanowicz, A., Mascarenhas, L., Amatruda, J. F., Ostrow, D., et al. (2023) · npj Precision Oncology · doi:10.1038/s41698-023-00357-0 · Cited by 55

Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure

The Dominantly Inherited Alzheimer Network (DIAN), Li, Z., Del-Aguila, J. L., Dube, U., Budde, J., Martinez, R., Black, K., Xiao, Q., Cairns, N. J., Dougherty, J. D., et al. (2018) · Genome Medicine · doi:10.1186/s13073-018-0551-4 · Cited by 56

Development of compact transcriptional effectors using high-throughput measurements in diverse contexts

Tycko, J., Van, M. V., Aradhana, DelRosso, N., Ye, H., Yao, D., Valbuena, R., Vaughan-Jackson, A., Xu, X., Ludwig, C., et al. (2025) · Nature Biotechnology · doi:10.1038/s41587-024-02442-6 · Cited by 57

Identification of Essential Genes and Fluconazole Susceptibility Genes in Candida glabrata by Profiling Hermes Transposon Insertions

Gale, A. N., Sakhawala, R. M., Levitan, A., Sharan, R., Berman, J., Timp, W., & Cunningham, K. W. (2020) · G3 Genes|Genomes|Genetics · doi:10.1534/g3.120.401595 · Cited by 56

DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency

Taguchi, J., Shibata, H., Kabata, M., Kato, M., Fukuda, K., Tanaka, A., Ohta, S., Ukai, T., Mitsunaga, K., Yamada, Y., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-25249-4 · Cited by 46

Regulation of angiopoietin-like protein 4 production during and after exercise

Norheim, F., Hjorth, M., Langleite, T. M., Lee, S., Holen, T., Bindesbøll, C., Stadheim, H. K., Gulseth, H. L., Birkeland, K. I., Kielland, A., et al. (2014) · Physiological Reports · doi:10.14814/phy2.12109 · Cited by 53

Rational engineering of a functional CpG-free ITR for AAV gene therapy

Pan, X., Yue, Y., Boftsi, M., Wasala, L. P., Tran, N. T., Zhang, K., Pintel, D. J., Tai, P. W. L., & Duan, D. (2022) · Gene Therapy · doi:10.1038/s41434-021-00296-0 · Cited by 53

Single-molecule states link transcription factor binding to gene expression

Doughty, B. R., Hinks, M. M., Schaepe, J. M., Marinov, G. K., Thurm, A. R., Rios-Martinez, C., Parks, B. E., Tan, Y., Marklund, E., Dubocanin, D., et al. (2024) · Nature · doi:10.1038/s41586-024-08219-w · Cited by 42

Conserved effect of aging on DNA methylation and association with EZH2 polycomb protein in mice and humans

Mozhui, K., & Pandey, A. K. (2017) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2017.02.006 · Cited by 46

Unbiased transcription factor CRISPR screen identifies ZNF800 as master repressor of enteroendocrine differentiation

Lin, L., DeMartino, J., Wang, D., van Son, G. J. F., van der Linden, R., Begthel, H., Korving, J., Andersson-Rolf, A., van den Brink, S., Lopez-Iglesias, C., et al. (2023) · Science · doi:10.1126/science.adi2246 · Cited by 50

Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor roquin2

Choi, J., Lee, K., Ingvarsdottir, K., Bonasio, R., Saraf, A., Florens, L., Washburn, M. P., Tadros, S., Green, M. R., & Busino, L. (2018) · Nature Cell Biology · doi:10.1038/s41556-018-0084-5 · Cited by 50

An Updated Collection of Sequence Barcoded Temperature-Sensitive Alleles of Yeast Essential Genes

Kofoed, M., Milbury, K. L., Chiang, J. H., Sinha, S., Ben-Aroya, S., Giaever, G., Nislow, C., Hieter, P., & Stirling, P. C. (2015) · G3 Genes|Genomes|Genetics · doi:10.1534/g3.115.019174 · Cited by 48

An organoid-based drug screening identified a menin-MLL inhibitor for endometrial cancer through regulating the HIF pathway

Chen, J., Zhao, L., Peng, H., Dai, S., Quan, Y., Wang, M., Wang, J., Bi, Z., Zheng, Y., Zhou, S., et al. (2021) · Cancer Gene Therapy · doi:10.1038/s41417-020-0190-y · Cited by 46

A point mutation in the ion conduction pore of AMPA receptor GRIA3 causes dramatically perturbed sleep patterns as well as intellectual disability

Davies, B., Brown, L. A., Cais, O., Watson, J., Clayton, A. J., Chang, V. T., Biggs, D., Preece, C., Hernandez-Pliego, P., Krohn, J., et al. (2017) · Human Molecular Genetics · doi:10.1093/hmg/ddx270 · Cited by 48

Parasex Generates Phenotypic Diversity de Novo and Impacts Drug Resistance and Virulence in Candida albicans

Hirakawa, M. P., Chyou, D. E., Huang, D., Slan, A. R., & Bennett, R. J. (2017) · Genetics · doi:10.1534/genetics.117.300295 · Cited by 47

Identification of Genomic Binding Sites for Candida glabrata Pdr1 Transcription Factor in Wild-Type and ρ 0 Cells

Paul, S., Bair, T. B., & Moye-Rowley, W. S. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.03921-14 · Cited by 45

Integrating healthcare and research genetic data empowers the discovery of 28 novel developmental disorders

Kaplanis, J., Samocha, K. E., Wiel, L., Zhang, Z., Arvai, K. J., Eberhardt, R. Y., Gallone, G., Lelieveld, S. H., Martin, H. C., McRae, J. F., et al. (2019) · doi:10.1101/797787 · Cited by 36

Selection Signatures in Tropical Cattle Are Enriched for Promoter and Coding Regions and Reveal Missense Mutations in the Damage Response Gene HELB

Naval-Sánchez, M., Porto-Neto, L. R., Cardoso, D. F., Hayes, B. J., Daetwyler, H. D., Kijas, J., & Reverter, A. (2020) · Genetics Selection Evolution · doi:10.1186/s12711-020-00546-6 · Cited by 43

Fungal acetylome comparative analysis identifies an essential role of acetylation in human fungal pathogen virulence

Li, Y., Li, H., Sui, M., Li, M., Wang, J., Meng, Y., Sun, T., Liang, Q., Suo, C., Gao, X., et al. (2019) · Communications Biology · doi:10.1038/s42003-019-0419-1 · Cited by 42

An ABCA4 loss-of-function mutation causes a canine form of Stargardt disease

Mäkeläinen, S., Gòdia, M., Hellsand, M., Viluma, A., Hahn, D., Makdoumi, K., Zeiss, C. J., Mellersh, C., Ricketts, S. L., Narfström, K., et al. (2019) · PLOS Genetics · doi:10.1371/journal.pgen.1007873 · Cited by 41

Genome-Wide Association Analysis Reveals QTL and Candidate Mutations Involved in White Spotting in Cattle

Jivanji, S., Worth, G., Lopdell, T. J., Yeates, A., Couldrey, C., Reynolds, E., Tiplady, K., McNaughton, L., Johnson, T. J. J., Davis, S. R., et al. (2019) · Genetics Selection Evolution · doi:10.1186/s12711-019-0506-2 · Cited by 41

Prenatal Exposure to a Maternal High-Fat Diet Affects Histone Modification of Cardiometabolic Genes in Newborn Rats

Upadhyaya, B., Larsen, T., Barwari, S., Louwagie, E., Baack, M., & Dey, M. (2017) · Nutrients · doi:10.3390/nu9040407 · Cited by 40

Quantification of Translocation-Specific ctDNA Provides an Integrating Parameter for Early Assessment of Treatment Response and Risk Stratification in Ewing Sarcoma

Krumbholz, M., Eiblwieser, J., Ranft, A., Zierk, J., Schmidkonz, C., Stütz, A. M., Peneder, P., Tomazou, E. M., Agaimy, A., Bäuerle, T., et al. (2021) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-21-1324 · Cited by 39

Genetic interaction mapping informs integrative structure determination of protein complexes

Braberg, H., Echeverria, I., Bohn, S., Cimermancic, P., Shiver, A., Alexander, R., Xu, J., Shales, M., Dronamraju, R., Jiang, S., et al. (2020) · Science · doi:10.1126/science.aaz4910 · Cited by 37

Non-invasive analysis of intestinal development in preterm and term infants using RNA-Sequencing

Knight, J. M., Davidson, L. A., Herman, D., Martin, C. R., Goldsby, J. S., Ivanov, I. V., Donovan, S. M., & Chapkin, R. S. (2014) · Scientific Reports · doi:10.1038/srep05453 · Cited by 36

Single-cell transcriptogenomics reveals transcriptional exclusion of ENU-mutated alleles

Li, W., Calder, R. B., Mar, J. C., & Vijg, J. (2015) · Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis · doi:10.1016/j.mrfmmm.2015.01.002 · Cited by 34

Mammary-specific gene activation is defined by progressive recruitment of STAT5 during pregnancy and the establishment of H3K4me3 marks

Kang, K., Yamaji, D., Yoo, K. H., Robinson, G. W., & Hennighausen, L. (2014) · Molecular and Cellular Biology · doi:10.1128/mcb.00988-13 · Cited by 35

SOX9 reprograms endothelial cells by altering the chromatin landscape

Fuglerud, B. M., Drissler, S., Lotto, J., Stephan, T. L., Thakur, A., Cullum, R., & Hoodless, P. A. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac652 · Cited by 35

Transcriptomics and Phenotyping Define Genetic Signatures Associated with Echinocandin Resistance in Candida auris

Jenull, S., Shivarathri, R., Tsymala, I., Penninger, P., Trinh, P.-C., Nogueira, F., Chauhan, M., Singh, A., Petryshyn, A., Stoiber, A., et al. (2022) · mBio · doi:10.1128/mbio.00799-22 · Cited by 32

The Genomic Natural History of the Aurochs

Rossi, C., Sinding, M.-H. S., Mullin, V. E., Scheu, A., Erven, J. A. M., Verdugo, M. P., Daly, K. G., Ciucani, M. M., Mattiangeli, V., Teasdale, M. D., et al. (2024) · Nature · doi:10.1038/s41586-024-08112-6 · Cited by 32

Cellular reprogramming in vivo initiated by SOX4 pioneer factor activity

Katsuda, T., Sussman, J. H., Ito, K., Katznelson, A., Yuan, S., Takenaka, N., Li, J., Merrell, A. J., Cure, H., Li, Q., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-45939-z · Cited by 33

DeNovoCNN: a deep learning approach to de novo variant calling in next generation sequencing data

Khazeeva, G., Sablauskas, K., van der Sanden, B., Steyaert, W., Kwint, M., Rots, D., Hinne, M., van Gerven, M., Yntema, H., Vissers, L., et al. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac511 · Cited by 30

Motif oriented high-resolution analysis of ChIP-seq data reveals the topological order of CTCF and cohesin proteins on DNA

Nagy, G., Czipa, E., Steiner, L., Nagy, T., Pongor, S., Nagy, L., & Barta, E. (2016) · BMC Genomics · doi:10.1186/s12864-016-2940-7 · Cited by 27

The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency

Athanasouli, P., Balli, M., De Jaime-Soguero, A., Boel, A., Papanikolaou, S., van der Veer, B. K., Janiszewski, A., Vanhessche, T., Francis, A., El Laithy, Y., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-36914-1 · Cited by 31

Mitochondrial Sequence Variation in African-American Primary Open-Angle Glaucoma Patients

Collins, D. W., Gudiseva, H. V., Trachtman, B. T., Jerrehian, M., Gorry, T., Merritt III, W. T., Rhodes, A. L., Sankar, P. S., Regina, M., Miller-Ellis, E., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0076627 · Cited by 27

Diagnostic utility of DNA methylation analysis in genetically unsolved pediatric epilepsies and CHD2 episignature refinement

LaFlamme, C. W., Rastin, C., Sengupta, S., Pennington, H. E., Russ-Hall, S. J., Schneider, A. L., Bonkowski, E. S., Almanza Fuerte, E. P., Allan, T. J., Zalusky, M. P.-G., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-50159-6 · Cited by 31

Redefining pleiotropic drug resistance in a pathogenic yeast: Pdr1 functions as a sensor of cellular stresses in Candida glabrata

Gale, A. N., Pavesic, M. W., Nickels, T. J., Xu, Z., Cormack, B. P., & Cunningham, K. W. (2023) · mSphere · doi:10.1128/msphere.00254-23 · Cited by 27

Overlooked Candida glabrata petites are echinocandin tolerant, induce host inflammatory responses, and display poor in vivo fitness

Arastehfar, A., Daneshnia, F., Hovhannisyan, H., Fuentes, D., Cabrera, N., Quinteros, C., Ilkit, M., Ünal, N., Hilmioğlu-Polat, S., Jabeen, K., et al. (2023) · mBio · doi:10.1128/mbio.01180-23 · Cited by 27

Three-dimensional interactions between enhancers and promoters during intestinal differentiation depend upon HNF4

Chen, L., Cao, W., Aita, R., Aldea, D., Flores, J., Gao, N., Bonder, E. M., Ellison, C. E., & Verzi, M. P. (2021) · Cell Reports · doi:10.1016/j.celrep.2020.108679 · Cited by 27

Nucleotide excision repair removes thymidine analog 5-ethynyl-2′-deoxyuridine from the mammalian genome

Wang, L., Cao, X., Yang, Y., Kose, C., Kawara, H., Lindsey-Boltz, L. A., Selby, C. P., & Sancar, A. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2210176119 · Cited by 26

Membrane metalloprotease TRABD2A restricts HIV-1 progeny production in resting CD4+ T cells by degrading viral Gag polyprotein

Liang, G., Zhao, L., Qiao, Y., Geng, W., Zhang, X., Liu, M., Dong, J., Ding, H., Sun, H., & Shang, H. (2019) · Nature Immunology · doi:10.1038/s41590-019-0385-2 · Cited by 24

Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma

Lutz, R., Poos, A. M., Solé-Boldo, L., John, L., Wagner, J., Prokoph, N., Baertsch, M. A., Vonficht, D., Palit, S., Brobeil, A., et al. (2025) · Science Immunology · doi:10.1126/sciimmunol.adp6667 · Cited by 25

Clinical implementation of plasma cell-free circulating tumor DNA quantification by digital droplet PCR for the monitoring of Ewing sarcoma in children and adolescents

Seidel, M. G., Kashofer, K., Moser, T., Thueringer, A., Liegl-Atzwanger, B., Leithner, A., Szkandera, J., Benesch, M., El-Heliebi, A., & Heitzer, E. (2022) · Frontiers in Pediatrics · doi:10.3389/fped.2022.926405 · Cited by 24

Non-homologous end-joining-deficient filamentous fungal strains mitigate the impact of off-target mutations during the application of CRISPR/Cas9

Garrigues, S., Peng, M., Kun, R. S., & de Vries, R. P. (2023) · mBio · doi:10.1128/mbio.00668-23 · Cited by 22

The AAV2.7m8 capsid packages a higher degree of heterogeneous vector genomes than AAV2

Cui, M., Su, Q., Yip, M., McGowan, J., Punzo, C., Gao, G., & Tai, P. W. L. (2024) · Gene Therapy · doi:10.1038/s41434-024-00477-7 · Cited by 20

The Wild West of spike-in normalization

Patel, L. A., Cao, Y., Mendenhall, E. M., Benner, C., & Goren, A. (2024) · Nature Biotechnology · doi:10.1038/s41587-024-02377-y · Cited by 20

Retinal gene therapy for Stargardt disease with dual AAV intein vectors is both safe and effective in large animal models

Ferla, R., Pugni, E., Lupo, M., Tiberi, P., Fioretto, F., Perota, A., Duchi, R., Lagutina, I., Gesualdo, C., Rossi, S., et al. (2025) · Science Advances · doi:10.1126/sciadv.adt9354 · Cited by 19

Epigenetic changes associated with early life experiences: saliva, a biospecimen for dna methylation signatures

Bearer, E. L., & Mulligan, B. S. (2018) · Current Genomics · doi:10.2174/1389202919666180307150508 · Cited by 19

Discovery of a Novel CIP2A Variant (NOCIVA) with Clinical Relevance in Predicting TKI Resistance in Myeloid Leukemias

Mäkelä, E., Pavic, K., Varila, T., Salmenniemi, U., Löyttyniemi, E., Nagelli, S. G., Ammunét, T., Kähäri, V.-M., Clark, R. E., Elo, L. L., et al. (2021) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-20-3679 · Cited by 18

Genotyping of Circulating Free DNA Enables Monitoring of Tumor Dynamics in Synovial Sarcomas

Eisenhardt, A. E., Brugger, Z., Lausch, U., Kiefer, J., Zeller, J., Runkel, A., Schmid, A., Bronsert, P., Wehrle, J., Leithner, A., et al. (2022) · Cancers · doi:10.3390/cancers14092078 · Cited by 18

Acetylation-dependent regulation of core spliceosome modulates hepatocellular carcinoma cassette exons and sensitivity to PARP inhibitors

Sun, L., Liu, Y., Guo, X., Cui, T., Wu, C., Tao, J., Cheng, C., Chu, Q., Ji, C., Li, X., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-49573-7 · Cited by 18

Candida auris skin tropism and antifungal resistance are mediated by carbonic anhydrase Nce103

Phan-Canh, T., Coman, C., Lackner, M., Troppmair, N., Müller, C., Cerbu, D., Seiser, S., Penninger, P., Tsymala, I., Khunweeraphong, N., et al. (2025) · Nature Microbiology · doi:10.1038/s41564-025-02189-z · Cited by 16

Somatic cancer variants enriched in Alzheimer’s disease microglia-like cells drive inflammatory and proliferative states

Huang, A. Y., Zhou, Z., Talukdar, M., Enyenihi, L., Miller, M. B., Chhouk, B., Rosen, I., Zheng, M., Zhou, M., Yang, A., et al. (2026) · Cell · doi:10.1016/j.cell.2026.03.040 · Cited by 15

SIRT7 regulates NUCKS1 chromatin binding to elicit metabolic and inflammatory gene expression in senescence and liver aging

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