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Mitochondria: In Sickness and in Health

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The new mutation, E46K, of α‐synuclein causes parkinson and Lewy body dementia

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Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice

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Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease

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Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease

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Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

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Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease

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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

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α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

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Dopaminergic Loss and Inclusion Body Formation in α-Synuclein Mice: Implications for Neurodegenerative Disorders

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Stabilization of α-Synuclein Secondary Structure upon Binding to Synthetic Membranes

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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

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Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death

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Oxidative Damage Linked to Neurodegeneration by Selective α-Synuclein Nitration in Synucleinopathy Lesions

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Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy

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In vivo demonstration that α-synuclein oligomers are toxic

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Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein

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α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models

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Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

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The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

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α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

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Chaperone Suppression of α-Synuclein Toxicity in a <i>Drosophila</i> Model for Parkinson's Disease

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α-Synuclein strains cause distinct synucleinopathies after local and systemic administration

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Kinetic Stabilization of the α-Synuclein Protofibril by a Dopamine-α-Synuclein Adduct

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Cell-produced α-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival

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Sirtuin 2 Inhibitors Rescue α-Synuclein-Mediated Toxicity in Models of Parkinson's Disease

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Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

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Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies

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α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration

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Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

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Structure and function of ER membrane contact sites with other organelles

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Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

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Structural and functional characterization of two alpha-synuclein strains

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Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

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Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

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Structural disorder of monomeric α-synuclein persists in mammalian cells

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Synaptic Vesicle Depletion Correlates with Attenuated Synaptic Responses to Prolonged Repetitive Stimulation in Mice Lacking α-Synuclein

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Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

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PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease

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Exosomal cell-to-cell transmission of alpha synuclein oligomers

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Microglial activation and dopamine terminal loss in early Parkinson's disease

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Multiple-System Atrophy

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The function of α-synuclein

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α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

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Yeast Cells Provide Insight into Alpha-Synuclein Biology and Pathobiology

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Spreading of pathology in neurodegenerative diseases: a focus on human studies

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Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

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Synucleins Are Developmentally Expressed, and α-Synuclein Regulates the Size of the Presynaptic Vesicular Pool in Primary Hippocampal Neurons

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TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity

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Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3

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G51D α‐synuclein mutation causes a novel Parkinsonian–pyramidal syndrome

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The role of protein clearance mechanisms in organismal ageing and age-related diseases

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Parkinson's Disease α-Synuclein Transgenic Mice Develop Neuronal Mitochondrial Degeneration and Cell Death

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Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons

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Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

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Alpha‐synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease

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Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation

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Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

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Subcellular Localization of Wild-Type and Parkinson's Disease-Associated Mutant α-Synuclein in Human and Transgenic Mouse Brain

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Dopamine-modified α-synuclein blocks chaperone-mediated autophagy

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