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Evidence that fragile X mental retardation protein is a negative regulator of translation

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Abnormal Development of Dendritic Spines in<i>FMR1</i>Knock-Out Mice

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Dysregulation of mTOR signaling in fragile X syndrome

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Imbalance of Neocortical Excitation and Inhibition and Altered UP States Reflect Network Hyperexcitability in the Mouse Model of Fragile X Syndrome

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Molecular Mechanisms of Fragile X Syndrome: A Twenty-Year Perspective

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FMRP Associates with Polyribosomes as an mRNP, and the I304N Mutation of Severe Fragile X Syndrome Abolishes This Association

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Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

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Pharmacological Rescue of Synaptic Plasticity, Courtship Behavior, and Mushroom Body Defects in a Drosophila Model of Fragile X Syndrome

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Dynamic Translational and Proteasomal Regulation of Fragile X Mental Retardation Protein Controls mGluR-Dependent Long-Term Depression

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Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model

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The fragile X mental retardation protein inhibits translation via interacting with mRNA

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Minocycline and Neurodegenerative Diseases

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Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis

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Biochemical mechanisms for translational regulation in synaptic plasticity

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A pilot open label, single dose trial of fenobam in adults with fragile X syndrome

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Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways

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Hypersensitivity to mGluR5 and ERK1/2 Leads to Excessive Protein Synthesis in the Hippocampus of a Mouse Model of Fragile X Syndrome

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HITS-CLIP: panoramic views of protein-RNA regulation in living cells

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Exaggerated translation causes synaptic and behavioural aberrations associated with autism

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The Pathophysiology of Fragile X (and What It Teaches Us about Synapses)

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Rho GTPases, dendritic structure, and mental retardation

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Making synaptic plasticity and memory last: mechanisms of translational regulationPreprint

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Effects of STX209 (Arbaclofen) on Neurobehavioral Function in Children and Adults with Fragile X Syndrome: A Randomized, Controlled, Phase 2 Trial

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Delayed Stabilization of Dendritic Spines in Fragile X Mice

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Sequence-Specific RNA Binding by a Nova KH Domain

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Decreased expression of the GABAA receptor in fragile X syndrome

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Genetic Removal of p70 S6 Kinase 1 Corrects Molecular, Synaptic, and Behavioral Phenotypes in Fragile X Syndrome Mice

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Metabotropic Receptor-Dependent Long-Term Depression Persists in the Absence of Protein Synthesis in the Mouse Model of Fragile X Syndrome

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Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes

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Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells

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Reduced Cortical Synaptic Plasticity and GluR1 Expression Associated with Fragile X Mental Retardation Protein Deficiency

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SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons

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Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses

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Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila

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Critical period plasticity is disrupted in the barrel cortex of FMR1 knockout mice

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Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome

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Reversal of Disease-Related Pathologies in the Fragile X Mouse Model by Selective Activation of GABA _B Receptors with Arbaclofen

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Homer Interactions Are Necessary for Metabotropic Glutamate Receptor-Induced Long-Term Depression and Translational Activation

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Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome

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The fragile X mental retardation protein is associated with poly(A)+ mRNA in actively translating polyribosomes

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Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile X syndrome

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Open-label add-on treatment trial of minocycline in fragile X syndrome.

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Decreased GABAA receptor expression in the seizure-prone fragile X mouse

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Excess protein synthesis in Drosophila Fragile X mutants impairs long-term memory

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Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome

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The FXG: a presynaptic fragile X granule expressed in a subset of developing brain circuits

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GSK3 Influences Social Preference and Anxiety-Related Behaviors during Social Interaction in a Mouse Model of Fragile X Syndrome and Autism

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Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles

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The role of protein synthesis during the labile phases of memory: Revisiting the skepticism

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Inhibition of GSK3 improves hippocampus-dependent learning and rescues neurogenesis in a mouse model of fragile X syndrome

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Fragile X Mental Retardation Protein Regulates the Levels of Scaffold Proteins and Glutamate Receptors in Postsynaptic Densities

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Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome

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Bidirectional Regulation of Dendritic Voltage-Gated Potassium Channels by the Fragile X Mental Retardation Protein

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Deregulation of <i>EIF4E</i>: a novel mechanism for autism

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Early developmental alterations in GABAergic protein expression in fragile X knockout mice

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Abnormal Presynaptic Short-Term Plasticity and Information Processing in a Mouse Model of Fragile X Syndrome

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A mouse model of the human Fragile X syndrome I304N mutation

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Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome

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Fragile X mental retardation protein is required for rapid experience-dependent regulation of the potassium channel Kv3.1b

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Altered Hippocampal Synaptic Plasticity in the <i>Fmr1</i> Gene Family Knockout Mouse Models

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Pharmacological treatment of fragile X syndrome with GABAergic drugs in a knockout mouse model

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Cytoplasmic RNA-Binding Proteins and the Control of Complex Brain FunctionPreprint

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Synaptic Plasticity and Translation InitiationPreprint

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Altered protein synthesis is a trigger for long-term memory formation

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Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome

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Conserved Hippocampal Cellular Pathophysiology but Distinct Behavioural Deficits in a New Rat Model of FXS

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