Cited by 65Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Oxytocin: Parallel Processing in the Social Brain?

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Dölen, Gül·2015·Journal of Neuroendocrinology

Abstract

Early studies attempting to disentangle the network complexity of the brain exploited the accessibility of sensory receptive fields to reveal circuits made up of synapses connected both in series and in parallel. More recently, extension of this organisational principle beyond the sensory systems has been made possible by the advent of modern molecular, viral and optogenetic approaches. Here, evidence supporting parallel processing of social behaviours mediated by oxytocin is reviewed. Understanding oxytocinergic signalling from this perspective has significant implications for the design of oxytocin‐based therapeutic interventions aimed at disorders such as autism, where disrupted social function is a core clinical feature. Moreover, identification of opportunities for novel technology development will require a better appreciation of the complexity of the circuit‐level organisation of the social brain.

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Registry

Crossref · 10.1111/jne.12284

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346 of 346 references verified0 citation errors · 0 not checkable

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Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Oxytocin is important for maternal physiology and childcare, including parturition and milk ejection during nursing.

    “Oxytocin is a neuropeptide that is important for maternal physiology and childcare, including parturition and milk ejection during nursing1–6.”
  • Central oxytocin release is involved in behaviours including reproduction, parental care and pair bonding.

    “whereas oxytocin release in the central nervous system is involved in a wide range of behaviours including reproduction, parental care and pair bonding5,6.”
  • Suckling triggers the release of oxytocin.

    “Suckling triggers the release of oxytocin, but other sensory cues—specifically, infant cries—can increase the levels of oxytocin in new human mothers7”
  • Peripheral oxytocin is important for milk ejection during nursing and uterine contractions during labour.

    “Peripheral oxytocin is important for milk ejection during nursing and uterine contractions during labour”

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Authors
Dölen, G.
Affiliations
Johns Hopkins University (US)
Corresponding author
Dölen, Gül
Venue
Journal of Neuroendocrinology
Publisher
Wiley
Published
2015-05-26
Volume
27
Issue
6
Pages
516-535
ISSN
  • 0953-8194 (ISSN-L)
  • 1365-2826
OpenAlex
W1980183526
Cited by
65
References
346
Citations by year
2026: 2 · 2025: 5 · 2024: 3 · 2023: 4 · 2022: 3 · 2021: 3 · 2020: 20 · 2019: 6 · 2018: 6 · 2017: 4 · 2016: 5 · 2015: 3 · 2013: 1
FWCI
0.94
Type
journal article
Language
en
Open access
Locations
  • Journal of Neuroendocrinology (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
Funders
Hartwell Foundation
Topics
  • Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords
oxytocin, parallel computing, social brain, social behavior, neural circuits, autism spectrum disorder, social dysfunction, therapeutic interventions, optogenetics, viral tracing
MeSH terms
Adolescent, Adult, Brain, Child, Humans, Male, Memory, Oxytocin, Social Behavior, Young Adult

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