CoChat
Sign Up
Cited by 1,823

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Generation of cerebral organoids from human pluripotent stem cells

Lancaster, Madeline A, Knoblich, Juergen A·2014·Nature Protocols
DOI 10.1038/nprot.2014.158PMC PMC4160653
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1038/nprot.2014.158

Cites

11 of 11 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Established unguided methods of spontaneous HNO culture, including the one used in this study, may introduce variability, stress, and cell death.

    “However, established unguided methods of spontaneous HNO culture, including the one used in this study48, may introduce variability, stress, and cell death96.”

    From GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau (2025) · cites this paper as [48]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 31

  1. Lanza, R., Gearhart, J., Hogan, B., Melton, D. & Pedersen, R. Essentials of Stem Cell Biology (Elsevier, 2009).
  2. Sato, T. & Clevers, H. Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications. Science 340, 1190–1194 (2013). · DOI · Paper page
  3. Sasai, Y., Eiraku, M. & Suga, H. In vitro organogenesis in three dimensions: self-organising stem cells. Development 139, 4111–4121 (2012). · DOI
  4. Eiraku, M. et al. Self-organizing optic-cup morphogenesis in three-dimensional culture. Nature 472, 51–56 (2011). · DOI · Paper page
  5. Suga, H. et al. Self-formation of functional adenohypophysis in three-dimensional culture. Nature 480, 57–62 (2011). · DOI
  6. Koehler, K.R., Mikosz, A.M., Molosh, A.I., Patel, D. & Hashino, E. Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture. Nature 500, 217–221 (2013). · DOI · Paper page
  7. Xia, Y. et al. Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells. Nat. Cell Biol. 15, 1507–1515 (2013). · DOI
  8. Takasato, M. et al. Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney. Nat. Cell Biol. 16, 118–126 (2014). · DOI
  9. Taguchi, A. et al. Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells. Cell Stem Cell 14, 53–67 (2014). · DOI
  10. Nakano, T. et al. Self-formation of optic cups and storable stratified neural retina from human ESCs. Cell Stem Cell 10, 771–785 (2012). · DOI · Paper page
  11. Spence, J.R. et al. Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro. Nature 470, 105–109 (2011). · DOI
  12. Humphreys, B.D. Kidney structures differentiated from stem cells. Nat. Cell Biol. 16, 19–21 (2013). · DOI
  13. Evans, M. Discovering pluripotency: 30 years of mouse embryonic stem cells. Nat. Rev. Mol. Cell Biol. 12, 680–686 (2011). · DOI
  14. Shevde, N.K. & Mael, A.A. Techniques in embryoid body formation from human pluripotent stem cells. Methods Mol. Biol. 946, 535–546 (2013). · DOI
  15. Zhang, S.C., Wernig, M., Duncan, I.D., Brüstle, O. & Thomson, J.A. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat. Biotechnol. 19, 1129–1133 (2001). · DOI
  16. Hu, B.-Y. & Zhang, S.-C. Directed differentiation of neural-stem cells and subtype-specific neurons from hESCs. Methods Mol. Biol. 636, 123–137 (2010). · DOI
  17. Wu, Y., Liu, Y., Chesnut, J.D. & Rao, M.S. Isolation of neural stem and precursor cells from rodent tissue. Methods Mol. Biol. 438, 39–53 (2008). · DOI
  18. Price, P.J. & Brewer, G.J. Serum-free media for neural cell cultures. In Protocols for Neural Cell Culture (eds. Federoff, S. and Richardson, A.) 255–264 (Humana Press, 2001). · DOI
  19. Brewer, G.J., Torricelli, J.R., Evege, E.K. & Price, P.J. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J. Neurosci. Res. 35, 567–576 (1993). · DOI · Paper page
  20. Koch, P., Opitz, T., Steinbeck, J.A., Ladewig, J. & Brüstle, O. A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration. Proc. Natl. Acad. Sci. USA 106, 3225–3230 (2009). · DOI
  21. Petros, T.J., Tyson, J.A. & Anderson, S.A. Pluripotent stem cells for the study of CNS development. Front. Mol. Neurosci. 4, 30 (2011). · DOI
  22. Eiraku, M. & Sasai, Y. Self-formation of layered neural structures in three-dimensional culture of ES cells. Curr. Opin. Neurobiol. 22, 768–777 (2012). · DOI
  23. Nasu, M. et al. Robust formation and maintenance of continuous stratified cortical neuroepithelium by laminin-containing matrix in mouse ES cell culture. PLoS ONE 7, e53024 (2012). · DOI
  24. Li, M.L. et al. Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells. Proc. Natl. Acad. Sci. USA 84, 136–140 (1987). · DOI
  25. Martin, I., Wendt, D. & Heberer, M. The role of bioreactors in tissue engineering. Trends Biotechnol. 22, 80–86 (2004). · DOI
  26. Conti, L. & Cattaneo, E. Neural stem cell systems: physiological players or in vitro entities? Nat. Rev. Neurosci. 11, 176–187 (2010). · DOI
  27. Shi, Y., Kirwan, P., Smith, J., Robinson, H.P.C. & Livesey, F.J. Human cerebral cortex development from pluripotent stem cells to functional excitatory synapses. Nat. Neurosci. 15, 477–86 S1 (2012). · DOI · Paper page
  28. Lamonica, B.E., Lui, J.H., Hansen, D.V. & Kriegstein, A.R. Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex. Nat. Commun. 4, 1665 (2013). · DOI
  29. Gilmore, E.C. & Walsh, C.A. Genetic causes of microcephaly and lessons for neuronal development. Wiley Interdiscip. Rev. Dev. Biol. 2, 461–478 (2013). · DOI
  30. Brennand, K.J. & Gage, F.H. Modeling psychiatric disorders through reprogramming. Dis. Model Mech. 5, 26–32 (2012). · DOI
  31. Koike, M., Kurosawa, H. & Amano, Y. A round-bottom 96-well polystyrene plate coated with 2-methacryloyloxyethyl phosphorylcholine as an effective tool for embryoid body formation. Cytotechnology 47, 3–10 (2005). · DOI

Cited by

Sorted by citations

Metadata

Authors
Lancaster, M. A., & Knoblich, J. A.
Venue
Nature Protocols
Publisher
Springer Science and Business Media LLC
Published
2014-09-04
Volume
9
Issue
10
Pages
2329-2340
ISSN
  • 1754-2189
  • 1750-2799
DOI
10.1038/nprot.2014.158
PMC
PMC4160653
Cited by
1,823
References
11
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review