70-year legacy of the Framingham Heart Study
Abstract
The Framingham Heart Study (FHS) was established in 1948 to improve understanding of the epidemiology of coronary heart disease (CHD) in the USA. In 1961, seminal work identified major risk factors for CHD (high blood pressure, high cholesterol levels and evidence on the electrocardiogram of left ventricular hypertrophy), which later formed the basis for multivariable 10-year and 30-year risk-prediction algorithms. The FHS cohorts now comprise three generations of participants (n ≈ 15,000) and two minority cohorts. The FHS cohorts are densely phenotyped, with recurring follow-up examinations and surveillance for cardiovascular and non-cardiovascular end points. Assessment of subclinical disease and physiological profiling of these cohorts (with the use of echocardiography, ambulatory electrocardiographic monitoring, exercise stress testing, cardiac CT, heart and brain MRI, serial vascular tonometry and accelerometry) have been performed repeatedly. Over the past decade, the FHS cohorts have undergone deep 'omics' profiling (including whole-genome sequencing, DNA methylation analysis, transcriptomics, high-throughput proteomics and metabolomics, and microbiome studies). The FHS is a rich, longitudinal, transgenerational and deeply phenotyped cohort study with a sustained focus on state-of-the-art epidemiological methods and technological advances to facilitate scientific discoveries.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The Framingham Heart Study has demonstrated that hypertension, coronary artery disease, cardiac hypertension and diabetes are cardiovascular risk factors associated with the future development of heart failure.
“Over its 74-year length, the Framingham Heart Study has demonstrated that hypertension, coronary artery disease, cardiac hypertension and diabetes are cardiovascular risk factors associated with the future development of heart failure [2,3].”
From Recent Experimental Studies of Maternal Obesity, Diabetes during Pregnancy and the Developmental Origins of Cardiovascular Disease (2022) · cites this paper as [3]
Cites
Grundy, S. M., Bilheimer, D. W., Chait, A., Clark, L. T., Denke, M. A., Havel, R. J., Hazzard, W. R., Hulley, S. B., Hunninghake, D. B., Kreisberg, R. A., et al. (1993) · JAMA · doi:10.1001/jama.269.23.3015 · Cited by 27,944 · see citing works
Expert Panel on Detection, E. (2001) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.285.19.2486 · Cited by 26,011 · see citing works
Prediction of coronary heart disease using risk factor categories
Wilson, P. W. F., D’Agostino, R. B., Levy, D., Belanger, A. M., Silbershatz, H., & Kannel, W. B. (1998) · Circulation · doi:10.1161/01.cir.97.18.1837 · Cited by 9,581 · see citing works
Self-citationLevy, D., Garrison, R. J., Savage, D. D., Kannel, W. B., & Castelli, W. P. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005313222203 · Cited by 5,699 · see citing works
Self-citationThe Spread of Obesity in a Large Social Network over 32 Years
Christakis, N. A., & Fowler, J. H. (2007) · New England Journal of Medicine · doi:10.1056/nejmsa066082 · Cited by 5,007 · see citing works
Impact of Atrial Fibrillation on the Risk of Death: The Framingham Heart Study
Benjamin, E. J., Wolf, P. A., D’Agostino, R. B., Silbershatz, H., Kannel, W. B., & Levy, D. (1998) · Circulation · doi:10.1161/01.cir.98.10.946 · Cited by 4,575 · see citing works
Self-citationHubert, H. B., Feinleib, M., McNamara, P. M., & Castelli, W. P. (1983) · Circulation · doi:10.1161/01.cir.67.5.968 · Cited by 4,241 · see citing works
Diabetes and cardiovascular disease. The Framingham study
Kannel, W. B. (1979) · JAMA · doi:10.1001/jama.241.19.2035 · Cited by 3,958 · see citing works
The natural history of congestive heart failure: the Framingham study
McKee, P. A., Castelli, W. P., McNamara, P. M., & Kannel, W. B. (1971) · New England Journal of Medicine · doi:10.1056/nejm197112232852601 · Cited by 3,448 · see citing works
Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease
Seshadri, S., Beiser, A., Selhub, J., Jacques, P. F., Rosenberg, I. H., D'Agostino, R. B., Wilson, P. W. F., & Wolf, P. A. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa011613 · Cited by 3,237 · see citing works
Obesity and the risk of heart failure
Kenchaiah, S., Evans, J. C., Levy, D., Wilson, P. W. F., Benjamin, E. J., Larson, M. G., Kannel, W. B., & Vasan, R. S. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020245 · Cited by 3,093 · see citing works
Self-citationDiabetes and Cardiovascular Disease: The Framingham Study
Kannel, W. B. (1979) · JAMA · doi:10.1001/jama.1979.03290450033020 · Cited by 2,936 · see citing works
Explaining the decrease in U.S. deaths from coronary disease, 1980–2000
Ford, E. S., Ajani, U. A., Croft, J. B., Critchley, J. A., Labarthe, D. R., Kottke, T. E., Giles, W. H., & Capewell, S. (2007) · New England Journal of Medicine · doi:10.1056/nejmsa053935 · Cited by 2,757 · see citing works
Benjamin, E. J. (1994) · JAMA · doi:10.1001/jama.1994.03510350050036 · Cited by 2,613 · see citing works
Self-citationThe collective dynamics of smoking in a large social network
Christakis, N. A., & Fowler, J. H. (2008) · New England Journal of Medicine · doi:10.1056/nejmsa0706154 · Cited by 2,390 · see citing works
The epidemiology of heart failure: The Framingham Study
Ho, K. K. L., Pinsky, J. L., Kannel, W. B., & Levy, D. A. (1993) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(93)90455-a · Cited by 2,230 · see citing works
Self-citationArterial Stiffness and Cardiovascular Events: The Framingham Heart Study
Mitchell, G. F., Hwang, S.-J., Vasan, R. S., Larson, M. G., Pencina, M. J., Hamburg, N. M., Vita, J. A., Levy, D., & Benjamin, E. J. (2010) · Circulation · doi:10.1161/circulationaha.109.886655 · Cited by 2,225 · see citing works
Self-citationThe progression from hypertension to congestive heart failure
Levy, D. (1996) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1996.03530440037034 · Cited by 2,155 · see citing works
Self-citationEpidemiological approaches to heart disease: the Framingham study
Dawber, T. R., Meadors, G. F., & Moore, F. E. (1951) · American Journal of Public Health and the Nations Health · doi:10.2105/ajph.41.3.279 · Cited by 2,148 · see citing works
Role of diabetes in congestive heart failure: The Framingham study
Kannel, W. B., Hjortland, M., & Castelli, W. P. (1974) · The American Journal of Cardiology · doi:10.1016/0002-9149(74)90089-7 · Cited by 2,090 · see citing works
Impact of High-Normal Blood Pressure on the Risk of Cardiovascular Disease
Vasan, R. S., Larson, M. G., Leip, E. P., Evans, J. C., O’Donnell, C. J., Kannel, W. B., & Levy, D. A. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa003417 · Cited by 2,079 · see citing works
Self-citationLifetime Risk for Development of Atrial Fibrillation: The Framingham Heart Study
Lloyd-Jones, D. M., Wang, T. J., Leip, E. P., Larson, M. G., Levy, D., Vasan, R. S., D’Agostino, R. B., Massaro, J. M., Beiser, A., Wolf, P. A., et al. (2004) · Circulation · doi:10.1161/01.cir.0000140263.20897.42 · Cited by 2,041 · see citing works
Self-citationGenetic variants in novel pathways influence blood pressure and cardiovascular disease risk
The International Consortium for Blood Pressure Genome-Wide Association Studies (2011) · Nature · doi:10.1038/nature10405 · Cited by 2,033 · see citing works
Self-citationWang, T. J., Larson, M. G., Levy, D., Vasan, R. S., Leip, E. P., Wolf, P. A., D’Agostino, R. B., Murabito, J. M., Kannel, W. B., & Benjamin, E. J. (2003) · Circulation · doi:10.1161/01.cir.0000072767.89944.6e · Cited by 1,970 · see citing works
Self-citationKANNEL, W. B., DAWBER, T. R., KAGAN, A., REVOTSKIE, N., & STOKES, J. (1961) · Annals of Internal Medicine · doi:10.7326/0003-4819-55-1-33 · Cited by 1,837 · see citing works
Impact of Reduced Heart Rate Variability on Risk for Cardiac Events: The Framingham Heart Study
Tsuji, H., Larson, M. G., Venditti, F. J., Manders, E. S., Evans, J. C., Feldman, C. L., & Levy, D. (1996) · Circulation · doi:10.1161/01.cir.94.11.2850 · Cited by 1,762 · see citing works
Self-citationThe Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective
Mahmood, S. S., Levy, D., Vasan, R. S., & Wang, T. J. (2014) · The Lancet · doi:10.1016/s0140-6736(13)61752-3 · Cited by 1,622 · see citing works
Self-citationEvolution and functional impact of rare coding variation from deep sequencing of human exomes
Tennessen, J. A., Bigham, A. W., O’Connor, T. D., Fu, W., Kenny, E. E., Gravel, S., McGee, S., Do, R., Liu, X., Jun, G., et al. (2012) · Science · doi:10.1126/science.1219240 · Cited by 1,613 · see citing works
Plasma Natriuretic Peptide Levels and the Risk of Cardiovascular Events and Death
Wang, T. J., Larson, M. G., Levy, D. A., Benjamin, E. J., Leip, E. P., Omland, T., Wolf, P. A., & Vasan, R. S. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa031994 · Cited by 1,527 · see citing works
Self-citationEpidemiologic assessment of chronic atrial fibrillation and risk of stroke: The fiamingham Study
Wolf, P. A., Dawber, T. R., Thomas, H. E., & Kannel, W. B. (1978) · Neurology · doi:10.1212/wnl.28.10.973 · Cited by 1,526 · see citing works
Obesity and the risk of new-onset atrial fibrillation
Wang, T. J. (2004) · JAMA · doi:10.1001/jama.292.20.2471 · Cited by 1,427 · see citing works
Residual Lifetime Risk for Developing Hypertension in Middle-aged Women and Men
Vasan, R. S., Beiser, A., Seshadri, S. S., Larson, M. G., Kannel, W. B., D’Agostino, R. B., & Levy, D. A. (2002) · JAMA · doi:10.1001/jama.287.8.1003 · Cited by 1,399 · see citing works
Self-citationMultiple Biomarkers for the Prediction of First Major Cardiovascular Events and Death
Wang, T. J., Gona, P. N., Larson, M. G., Tofler, G. H., Levy, D. A., Newton‐Cheh, C., Jacques, P. F., Rifai, N., Selhub, J., Robins, S. J., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa055373 · Cited by 1,342 · see citing works
Self-citationCongestive heart failure in subjects with normal versus reduced left ventricular ejection fraction
Vasan, R. S., Larson, S., Benjamin, E. J., Evans, J. C., Reiss, C. K., & Levy, D. (1999) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(99)00118-7 · Cited by 1,331 · see citing works
Self-citationGenome-wide Analysis of Genetic Loci Associated With Alzheimer Disease
Seshadri, S. (2010) · JAMA · doi:10.1001/jama.2010.574 · Cited by 1,219 · see citing works
Reduced heart rate variability and mortality risk in an elderly cohort. The Framingham Heart Study
Tsuji, H., Venditti, F. J., Manders, E. S., Evans, J. C., Larson, M. G., Feldman, C. L., & Levy, D. (1994) · Circulation · doi:10.1161/01.cir.90.2.878 · Cited by 1,114 · see citing works
Self-citationAortic Stiffness, Blood Pressure Progression, and Incident Hypertension
Kaess, B. M., Rong, J., Larson, M. G., Hamburg, N. M., Vita, J. A., Levy, D. A., Benjamin, E. J., Vasan, R. S., & Mitchell, G. F. (2012) · JAMA · doi:10.1001/2012.jama.10503 · Cited by 1,086 · see citing works
Self-citationVasan, R. S., Larson, M. G., Leip, E. P., Kannel, W. B., & Levy, D. A. (2001) · The Lancet · doi:10.1016/s0140-6736(01)06710-1 · Cited by 1,074 · see citing works
Self-citationIncidence of dementia over three decades in the Framingham heart study
Satizabal, C. L., Beiser, A. S., Chouraki, V., Chêne, G., Dufouil, C., & Seshadri, S. (2016) · New England Journal of Medicine · doi:10.1056/nejmoa1504327 · Cited by 1,051 · see citing works
Schnabel, R. B., SULLIVAN, L. M., Levy, D. A., Pencina, M. J., Massaro, J. M., D’Agostino, R. B., Newton‐Cheh, C., Yamamoto, J. F., Magnani, J. W., Tadros, T. M., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60443-8 · Cited by 1,038 · see citing works
Self-citationImpact of Obesity on Plasma Natriuretic Peptide Levels
Wang, T. J., Larson, M. G., Levy, D., Benjamin, E. J., Leip, E. P., Wilson, P. W. F., & Vasan, R. S. (2004) · Circulation · doi:10.1161/01.cir.0000112582.16683.ea · Cited by 1,022 · see citing works
Self-citationGenetic Associations with Valvular Calcification and Aortic Stenosis
Thanassoulis, G., Campbell, C. Y., Owens, D. S., Smith, J. G., Smith, A. V., Peloso, G. M., Kerr, K. F., Pechlivanis, S., Budoff, M. J., Harris, T. B., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1109034 · Cited by 1,008 · see citing works
The framingham offspring study. Design and preliminary data
Feinleib, M., Kannel, W. B., Garrison, R. J., McNamara, P. M., & Castelli, W. P. (1975) · Preventive Medicine · doi:10.1016/0091-7435(75)90037-7 · Cited by 931 · see citing works
Epigenetic Signatures of Cigarette Smoking
Joehanes, R., Just, A. C., Marioni, R. E., Pilling, L. C., Reynolds, L. M., Mandaviya, P. R., Guan, W., Xu, T., Elks, C. E., Aslibekyan, S. W., et al. (2016) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.116.001506 · Cited by 915 · see citing works
Self-citationAtrial Fibrillation Begets Heart Failure and Vice Versa
Santhanakrishnan, R., Wang, N., Larson, M. G., Magnani, J. W., McManus, D. D., Lubitz, S. A., Ellinor, P. T., Cheng, S. C., Vasan, R. S., Lee, D. S., et al. (2016) · Circulation · doi:10.1161/circulationaha.115.018614 · Cited by 874 · see citing works
Self-citationPredicting the 30-Year Risk of Cardiovascular Disease
Pencina, M. J., D’Agostino, R. B., Larson, M. G., Massaro, J. M., & Vasan, R. S. (2009) · Circulation · doi:10.1161/circulationaha.108.816694 · Cited by 864 · see citing works
Self-citationSplansky, G. L., Corey, D., Yang, Q., Atwood, L. D., Cupples, L. A., Benjamin, E. J., D'Agostino, R. B., Fox, C. S., Larson, M. G., Murabito, J. M., et al. (2007) · American Journal of Epidemiology · doi:10.1093/aje/kwm021 · Cited by 860 · see citing works
Self-citationEchocardiographically Detected Left Ventricular Hypertrophy: Prevalence and Risk Factors
Levy, D. A., Anderson, K. M., SAVAGE, D. D., Kannel, W. B., Christiansen, J. C., & Castelli, W. P. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-108-1-7 · Cited by 812 · see citing works
Self-citationEchocardiographic criteria for left ventricular hypertrophy: The Framingham heart study
Levy, D. A., Savage, D. D., Garrison, R. J., Anderson, K. M., Kannel, W. B., & Castelli, W. P. (1987) · The American Journal of Cardiology · doi:10.1016/0002-9149(87)91133-7 · Cited by 798 · see citing works
Self-citationMidlife vascular risk factor exposure accelerates structural brain aging and cognitive decline
Debette, S., Seshadri, S., Beiser, A., Au, R., Himali, J. J., Palumbo, C., Wolf, P. A., & DeCarli, C. (2011) · Neurology · doi:10.1212/wnl.0b013e318227b227 · Cited by 772 · see citing works
Cigarette smoking as a risk factor for stroke. The Framingham Study
Wolf, P. A. (1988) · JAMA · doi:10.1001/jama.259.7.1025 · Cited by 767 · see citing works
Multi-ethnic genome-wide association study for atrial fibrillation
Roselli, C., Chaffin, M. D., Weng, L.-C. C., Aeschbacher, S., Ahlberg, G., Albert, C. M., Almgren, P., Alonso, Á., Anderson, C. D., Aragam, K. G., et al. (2018) · Nature Genetics · doi:10.1038/s41588-018-0133-9 · Cited by 754 · see citing works
Self-citationEpidemiology of cardiovascular disease in young individuals
Andersson, C., & Vasan, R. S. (2017) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2017.154 · Cited by 719 · see citing works
Self-citationII. Coronary Heart Disease in the Framingham Study
Dawber, T. R., Moore, F. E., & Mann, G. V. (1957) · American Journal of Public Health and the Nations Health · doi:10.2105/ajph.47.4_pt_2.4 · Cited by 718 · see citing works
Stroke risk profile: adjustment for antihypertensive medication. The Framingham Study.
D’Agostino, R. B., Wolf, P. A., Belanger, A. J., & Kannel, W. B. (1994) · Stroke · doi:10.1161/01.str.25.1.40 · Cited by 714 · see citing works
Epidemiologic assessment of the role of blood pressure in stroke. The Framingham study
Kannel, W. B. (1970) · JAMA · doi:10.1001/jama.214.2.301 · Cited by 706 · see citing works
Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study
Elias, M. F., Elias, P. K., SULLIVAN, L. M., Wolf, P. A., & D’Agostino, R. B. (2003) · International Journal of Obesity · doi:10.1038/sj.ijo.802225 · Cited by 691 · see citing works
DeCarli, C., Massaro, J., Harvey, D., Hald, J., Tullberg, M., Au, R., Beiser, A., D’Agostino, R., & Wolf, P. A. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.05.004 · Cited by 680 · see citing works
Mahabadi, A. A., Massaro, J. M., Rosito, G. A., Levy, D. A., Murabito, J. M., Wolf, P. A., O’Donnell, C. J., Fox, C. S., & Hoffmann, U. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn573 · Cited by 655 · see citing works
Self-citationNatural history of asymptomatic left ventricular systolic dysfunction in the community
Wang, T. J., Evans, J. C., Benjamin, E. J., Levy, D., LeRoy, E. C., & Vasan, R. S. (2003) · Circulation · doi:10.1161/01.cir.0000085166.44904.79 · Cited by 633 · see citing works
Self-citationClinical Correlates and Heritability of Flow-Mediated Dilation in the Community
Benjamin, E. J., Larson, M. G., Keyes, M. J., Mitchell, G. F., Vasan, R. S., Keaney, J. F., Lehman, B. T., Fan, S., Osypiuk, E. W., & Vita, J. A. (2004) · Circulation · doi:10.1161/01.cir.0000112565.60887.1e · Cited by 608 · see citing works
Self-citationRole of Blood Pressure in the Development of Congestive Heart Failure: The Framingham Study
Kannel, W. B., Castelli, W. P., McNamara, P. M., McKee, P. A., & Feinleib, M. (1972) · New England Journal of Medicine · doi:10.1056/nejm197210192871601 · Cited by 603 · see citing works
Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring
Fox, C. S. (2004) · JAMA · doi:10.1001/jama.291.23.2851 · Cited by 600 · see citing works
Psaty, B. M., O'Donnell, C. J., Gudnason, V., Lunetta, K. L., Folsom, A. R., Rotter, J. I., Uitterlinden, A. G., Harris, T. B., Witteman, J. C. M., & Boerwinkle, E. (2009) · Circulation: Cardiovascular Genetics · doi:10.1161/circgenetics.108.829747 · Cited by 599 · see citing works
Primary and subsequent coronary risk appraisal: New results from the Framingham study
D’Agostino, R. B., Russell, M. W., Huse, D. M., Ellison, R. C., Silbershatz, H., Wilson, P. W. F., & Hartz, S. C. (2000) · American Heart Journal · doi:10.1016/s0002-8703(00)90236-9 · Cited by 588 · see citing works
Tsao, C. W., Lyass, A., Enserro, D. M., Larson, M. G., Ho, J. E., Kizer, J. R., Gottdiener, J. S., Psaty, B. M., & Vasan, R. S. (2018) · JACC Heart Failure · doi:10.1016/j.jchf.2018.03.006 · Cited by 576 · see citing works
Self-citationImpaired Heart Rate Response to Graded Exercise
Lauer, M. S., Okin, P. M., Larson, M. G., Evans, J. C., & Levy, D. A. (1996) · Circulation · doi:10.1161/01.cir.93.8.1520 · Cited by 532 · see citing works
Self-citationCigarette Smoking as a Risk Factor for Stroke
Wolf, P. A. (1988) · JAMA · doi:10.1001/jama.1988.03720070025028 · Cited by 508 · see citing works
Debette, S., Beiser, A., DeCarli, C., Au, R., Himali, J. J., Kelly-Hayes, M., Romero, J. R., Kase, C. S., Wolf, P. A., & Seshadri, S. (2010) · Stroke · doi:10.1161/strokeaha.109.570044 · Cited by 508 · see citing works
Vasan, R. S., Benjamin, E. J., Larson, M. G., Leip, E. P., Wang, T. J., Wilson, P. W. F., & Levy, D. (2002) · JAMA · doi:10.1001/jama.288.10.1252 · Cited by 493 · see citing works
Self-citationHo, K. K. L., Moody, G. B., Peng, C.-K., Mietus, J. E., Larson, M. G., Levy, D., & Goldberger, A. L. (1997) · Circulation · doi:10.1161/01.cir.96.3.842 · Cited by 489 · see citing works
Self-citationStroke Risk Profile Predicts White Matter Hyperintensity Volume: The Framingham Study
Jeerakathil, T., Wolf, P. A., Beiser, A., Massaro, J., Seshadri, S., D’Agostino, R. B., & DeCarli, C. (2004) · Stroke · doi:10.1161/01.str.0000135226.53499.85 · Cited by 479 · see citing works
Summary estimates of cholesterol used to predict coronary heart disease.
Castelli, W. P., Abbott, R. D., & McNamara, P. (1983) · Circulation · doi:10.1161/01.cir.67.4.730 · Cited by 473 · see citing works
Inflammatory markers and the risk of Alzheimer disease: The Framingham Study
Tan, Z. S., Beiser, A. S., Vasan, R. S., Roubenoff, R., Dinarello, C. A., Harris, T. B., Benjamin, E. J., Au, R., Kiel, D. P., Wolf, P. A., et al. (2007) · Neurology · doi:10.1212/01.wnl.0000263217.36439.da · Cited by 440 · see citing works
Self-citationYao, C., Chen, G., Song, C., Keefe, J., Mendelson, M., Huan, T., Sun, B. B., Laser, A., Maranville, J. C., Wu, H., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05512-x · Cited by 431 · see citing works
Self-citationAssociation of Plasma Leptin Levels With Incident Alzheimer Disease and MRI Measures of Brain Aging
Lieb, W. (2009) · JAMA · doi:10.1001/jama.2009.1836 · Cited by 428 · see citing works
Profile for Estimating Risk of Heart Failure
Kannel, W. B., D’Agostino, R. B., Silbershatz, H., Belanger, A. J., Wilson, P. W. F., & Levy, D. A. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.11.1197 · Cited by 422 · see citing works
Self-citationVasan, R. S., Larson, M. G., Benjamin, E. J., Evans, J. C., & Levy, D. (1997) · New England Journal of Medicine · doi:10.1056/nejm199705083361903 · Cited by 402 · see citing works
Self-citationA DNA methylation biomarker of alcohol consumption
Liu, C., Marioni, R. E., Hedman, Å. K., Pfeiffer, L., Tsai, P.-C., Reynolds, L. M., Just, A. C., Duan, Q., Boer, C. G., Tanaka, T., et al. (2018) · Molecular Psychiatry · doi:10.1038/mp.2016.192 · Cited by 402 · see citing works
Self-citationImportance of Systolic Blood Pressure in Older Americans
Izzo, J. L., Levy, D. A., & Black, H. R. (2000) · Hypertension · doi:10.1161/01.hyp.35.5.1021 · Cited by 401 · see citing works
Self-citationParental history is an independent risk factor for coronary artery disease: The Framingham Study
Myers, R. H., Kiely, D. K., Cupples, L. A., & Kannel, W. B. (1990) · American Heart Journal · doi:10.1016/0002-8703(90)90216-k · Cited by 394 · see citing works
Au, R., Massaro, J. M., Wolf, P. A., Young, M. E., Beiser, A., Seshadri, S., D’Agostino, R. B., & DeCarli, C. (2006) · Archives of Neurology · doi:10.1001/archneur.63.2.246 · Cited by 381 · see citing works
Local Shear Stress and Brachial Artery Flow-Mediated Dilation
Mitchell, G. F., Parise, H., Vita, J. A., Larson, M. G., Warner, E., Keaney, J. F., Keyes, M. J., Levy, D. A., Vasan, R. S., & Benjamin, E. J. (2004) · Hypertension · doi:10.1161/01.hyp.0000137305.77635.68 · Cited by 376 · see citing works
Self-citationStærk, L., Wang, B., Preis, S. R., Larson, M. G., Lubitz, S. A., Ellinor, P. T., McManus, D. D., Ko, D., Weng, L.-C. C., Lunetta, K. L., et al. (2018) · BMJ · doi:10.1136/bmj.k1453 · Cited by 375 · see citing works
Self-citationDementia After Stroke: The Framingham Study
Ivan, C. S., Seshadri, S., Beiser, A., Au, R., Kase, C. S., Kelly-Hayes, M., & Wolf, P. A. (2004) · Stroke · doi:10.1161/01.str.0000127810.92616.78 · Cited by 369 · see citing works
Kaess, B. M., Pedley, A., Massaro, J. M., Murabito, J. M., Hoffmann, U., & Fox, C. S. (2012) · Diabetologia · doi:10.1007/s00125-012-2639-5 · Cited by 347 · see citing works
Myers, R. H., Schaefer, E. J., Wilson, P. W. F., D'Agostino, R., Ordovas, J. M., Espino, A., Au, R., White, R. F., Knoefel, J. E., Cobb, J. L., et al. (1996) · Neurology · doi:10.1212/wnl.46.3.673 · Cited by 346 · see citing works
Mendelson, M., Marioni, R. E., Joehanes, R., Liu, C., Hedman, Å. K., Aslibekyan, S. W., Demerath, E. W., Guan, W., Zhi, D., Yao, C., et al. (2017) · PLoS Medicine · doi:10.1371/journal.pmed.1002215 · Cited by 343 · see citing works
Self-citationA Genome-wide Association Study of the Human Metabolome in a Community-Based Cohort
Rhee, E. P., Ho, J. E., Chen, M., Shen, D., Cheng, S. C., Larson, M. G., Ghorbani, A., Shi, X. D., Helenius, I. T., O’Donnell, C. J., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.06.013 · Cited by 318 · see citing works
Self-citationDNA methylation signatures of chronic low-grade inflammation are associated with complex diseases
WHI-EMPC Investigators, Ligthart, S., Disease, C. E. O. C. H., Marzi, C., Aslibekyan, S. W., Mendelson, M., Conneely, K. N., Tanaka, T., Colicino, E., Waite, L. L., et al. (2016) · Genome biology · doi:10.1186/s13059-016-1119-5 · Cited by 317 · see citing works
Self-citationAssociation Between Familial Atrial Fibrillation and Risk of New-Onset Atrial Fibrillation
Lubitz, S. A., Yin, X., Fontes, J. D., Magnani, J. W., Rienstra, M., Pai, M., Villalon, M. L., Vasan, R. S., Pencina, M. J., Levy, D., et al. (2010) · JAMA · doi:10.1001/jama.2010.1690 · Cited by 313 · see citing works
Self-citationA Risk Score for Predicting Near-Term Incidence of Hypertension: The Framingham Heart Study
Parikh, N. I., Pencina, M. J., Wang, T. J., Benjamin, E. J., Lanier, K. J., Levy, D. A., D’Agostino, R. B., Kannel, W. B., & Vasan, R. S. (2008) · Annals of Internal Medicine · doi:10.7326/0003-4819-148-2-200801150-00005 · Cited by 311 · see citing works
Self-citationPeloso, G. M., Auer, P. L., Bis, J. C., Voorman, A., Morrison, A. C., Stitziel, N. O., Brody, J. A., Khetarpal, S. A., Crosby, J. R., Fornage, M., et al. (2014) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2014.01.009 · Cited by 309 · see citing works
Self-citationSchnabel, R. B., Larson, M. G., Yamamoto, J. F., SULLIVAN, L. M., Pencina, M. J., Meigs, J. B., Tofler, G. H., Selhub, J., Jacques, P. F., Wolf, P. A., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.882241 · Cited by 290 · see citing works
Self-citationThe Natural History of Borderline Isolated Systolic Hypertension
Sagie, A., Larson, M. G., & Levy, D. A. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312233292602 · Cited by 290 · see citing works
Self-citationGWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy
Broer, L., Buchman, A. S., Deelen, J., Evans, D. S., Faul, J. D., Lunetta, K. L., Sebastiani, P., Smith, J. A., Smith, A. V., Tanaka, T., et al. (2014) · The Journals of Gerontology Series A · doi:10.1093/gerona/glu166 · Cited by 279 · see citing works
Self-citationCorrelates of Echocardiographic Indices of Cardiac Remodeling Over the Adult Life Course
Cheng, S. C., Xanthakis, V., SULLIVAN, L. M., Lieb, W., Massaro, J. M., Aragam, J. R., Benjamin, E. J., & Vasan, R. S. (2010) · Circulation · doi:10.1161/circulationaha.110.937821 · Cited by 277 · see citing works
Self-citationGenetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation
Weng, L.-C. C., Preis, S. R., Hulme, O. L., Larson, M. G., Choi, S. H., Wang, B., Trinquart, L., McManus, D. D., Stærk, L., Lin, H., et al. (2017) · Circulation · doi:10.1161/circulationaha.117.031431 · Cited by 271 · see citing works
Self-citationCigarette Smoking and Coronary Heart Disease
Doyle, J. T., Dawber, T. R., Kannel, W. B., Heslin, A. S., & Kahn, H. A. (1962) · New England Journal of Medicine · doi:10.1056/nejm196204192661602 · Cited by 270 · see citing works
Johnson, A. D., Yanek, L. R., Chen, M., Faraday, N. R., Larson, M. G., Tofler, G. H., Lin, S. J., Kraja, A. T., Province, M. A., Yang, Q., et al. (2010) · Nature Genetics · doi:10.1038/ng.604 · Cited by 266 · see citing works
Self-citationSocial Network Concordance in Food Choice Among Spouses, Friends, and Siblings
Pachucki, M. C., Jacques, P. F., & Christakis, N. A. (2011) · American Journal of Public Health · doi:10.2105/ajph.2011.300282 · Cited by 265 · see citing works
de Boer, R. A., Nayor, M. G., deFilippi, C. R., Enserro, D. M., Bhambhani, V., Kizer, J. R., Blaha, M. J., Brouwers, F. P. J., Cushman, M., Lima, J. A. C., et al. (2018) · JAMA Cardiology · doi:10.1001/jamacardio.2017.4987 · Cited by 264 · see citing works
Self-citationVasan, R. S., Larson, M. G., Levy, D., Evans, J. C., & Benjamin, E. J. (1997) · Circulation · doi:10.1161/01.cir.96.6.1863 · Cited by 248 · see citing works
Self-citationHoffmann, U., Massaro, J. M., D'Agostino, R. B., Kathiresan, S., Fox, C. S., & O'Donnell, C. J. (2016) · Journal of the American Heart Association · doi:10.1161/jaha.115.003144 · Cited by 239 · see citing works
Inflammatory biomarkers, cerebral microbleeds, and small vessel disease
Shoamanesh, A., Preis, S. R., Beiser, A., Vasan, R. S., Benjamin, E. J., Kase, C. S., Wolf, P. A., DeCarli, C. S., Romero, J. R., & Seshadri, S. S. (2015) · Neurology · doi:10.1212/wnl.0000000000001279 · Cited by 236 · see citing works
Self-citationStroke risk profile, brain volume, and cognitive function
Seshadri, S. S., Wolf, P. A., Beiser, A., Elias, M. F., Au, R., Kase, C. S., D’Agostino, R. B., & DeCarli, C. S. (2004) · Neurology · doi:10.1212/01.wnl.0000142968.22691.70 · Cited by 230 · see citing works
Morshedi‐Meibodi, A., Larson, M. G., Levy, D. A., O’Donnell, C. J., & Vasan, R. S. (2002) · The American Journal of Cardiology · doi:10.1016/s0002-9149(02)02706-6 · Cited by 228 · see citing works
Self-citationEpidemiology of Left Ventricular Systolic Dysfunction and Heart Failure in the Framingham Study
Vasan, R. S., Xanthakis, V., Lyass, A., Andersson, C., Tsao, C. W., Cheng, S. C., Aragam, J. R., Benjamin, E. J., & Larson, M. G. (2017) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2017.08.007 · Cited by 228 · see citing works
Self-citationDNA Methylation Analysis Identifies Loci for Blood Pressure Regulation
Richard, M. A., Huan, T., Ligthart, S., Gondalia, R., Jhun, M. A., Brody, J. A., Irvin, M. R., Marioni, R. E., Shen, J., Tsai, P.-C., et al. (2017) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2017.09.028 · Cited by 225 · see citing works
Self-citationDoyle, J. T., Dawber, T. R., Kannel, W. B., Kinch, S. H., & Kahn, H. A. (1964) · PubMed · Cited by 221 · see citing works
Patel, M. S., Benjamin, E. J., Volpp, K. G., Fox, C. S., Small, D. S., Massaro, J. M., Lee, J. J., Hilbert, V., Valentino, M., Taylor, D. H., et al. (2017) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2017.3458 · Cited by 218 · see citing works
Self-citationVisceral and Subcutaneous Fat Quality and Cardiometabolic Risk
Rosenquist, K. J., Pedley, A., Massaro, J. M., Therkelsen, K. E., Murabito, J. M., Hoffmann, U., & Fox, C. S. (2013) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2012.11.021 · Cited by 216 · see citing works
Reporting genetic results in research studies: Summary and recommendations of an NHLBI working group
Bookman, E., Langehorne, A. A., Eckfeldt, J. H., Glass, K. C., Jarvik, G. P., Klag, M. J., Koski, G., Motulsky, A. G., Wilfond, B. S., Manolio, T. A., et al. (2006) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.31195 · Cited by 212 · see citing works
Cupples, L. A., Arruda, H. T., Benjamin, E. J., D’Agostino, R. B., Demissie, S., DeStefano, A. L., Dupuis, J., Falls, K. M., Fox, C. S., Gottlieb, D. J., et al. (2007) · BMC Medical Genetics · doi:10.1186/1471-2350-8-s1-s1 · Cited by 212 · see citing works
Self-citationLongitudinal Tracking of Left Ventricular Mass Over the Adult Life Course
Lieb, W., Xanthakis, V., SULLIVAN, L. M., Aragam, J. R., Pencina, M. J., Larson, M. G., Benjamin, E. J., & Vasan, R. S. (2009) · Circulation · doi:10.1161/circulationaha.108.824243 · Cited by 201 · see citing works
Self-citationLee, J., Pedley, A., Hoffmann, U., Massaro, J. M., & Fox, C. S. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.06.067 · Cited by 199 · see citing works
Epigenome-wide association studies identify DNA methylation associated with kidney function
Chu, A. Y., Tin, A., Schlosser, P., Ko, Y., Qiu, C., Yao, C., Joehanes, R., Grams, M. E., Liang, L., Gluck, C. A., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-01297-7 · Cited by 198 · see citing works
Self-citationAssociation of parental heart failure with risk of heart failure in offspring
Lee, D. S., Pencina, M. J., Benjamin, E. J., Wang, T. J., Levy, D., O'Donnell, C. J., Nam, B.-H., Larson, M. G., D'Agostino, R. B., & Vasan, R. S. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa052948 · Cited by 191 · see citing works
Self-citationHo, J. E., Larson, M. G., Ghorbani, A., Cheng, S. C., Chen, M., Keyes, M. J., Rhee, E. P., Clish, C. B., Vasan, R. S., Gerszten, R. E., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0148361 · Cited by 188 · see citing works
Self-citationCorrelated genotypes in friendship networks
Fowler, J. H., Settle, J. E., & Christakis, N. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1011687108 · Cited by 188 · see citing works
Hoffmann, U., Massaro, J. M., Fox, C. S., Manders, E. S., & O’Donnell, C. J. (2008) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2008.06.038 · Cited by 184 · see citing works
Multiple Biomarkers and the Risk of Incident Hypertension
Wang, T. J., Gona, P. N., Larson, M. G., Levy, D. A., Benjamin, E. J., Tofler, G. H., Jacques, P. F., Meigs, J. B., Rifai, N., Selhub, J., et al. (2007) · Hypertension · doi:10.1161/01.hyp.0000256956.61872.aa · Cited by 179 · see citing works
Self-citationGenome-wide identification of microRNA expression quantitative trait loci
Huan, T., Rong, J., Liu, C., Zhang, X., Tanriverdi, K., Joehanes, R., Chen, B. H., Murabito, J. M., Yao, C., Courchesne, P., et al. (2015) · Nature Communications · doi:10.1038/ncomms7601 · Cited by 175 · see citing works
Self-citationJoehanes, R., Zhang, X., Huan, T., Yao, C., Ying, S., Nguyen, Q. T., Demirkale, C. Y., Feolo, M., Sharopova, N., Sturcke, A., et al. (2017) · Genome biology · doi:10.1186/s13059-016-1142-6 · Cited by 175 · see citing works
Self-citationSinner, M. F., Stepas, K. A., Moser, C., Krijthe, B. P., Aspelund, T., Sotoodehnia, N., Fontes, J. D., Janssens, A. C. J. W., Kronmal, R. A., Magnani, J. W., et al. (2014) · EP Europace · doi:10.1093/europace/euu175 · Cited by 172 · see citing works
Self-citationImpact of high-normal blood pressure on the risk of cardiovascular disease
Vasan, R. S., Larson, M. G., & Leip, E. P. (2002) · ACC Current Journal Review · doi:10.1016/s1062-1458(02)00536-6 · Cited by 171 · see citing works
Self-citationTsao, C. W., Gona, P. N., Salton, C. J., Chuang, M. L., Levy, D. A., Manning, W. J., & O’Donnell, C. J. (2015) · Journal of the American Heart Association · doi:10.1161/jaha.115.002188 · Cited by 170 · see citing works
Self-citationDistinct metabolomic signatures are associated with longevity in humans
Cheng, S. C., Larson, M. G., McCabe, E. L., Murabito, J. M., Rhee, E. P., Ho, J. E., Jacques, P. F., Ghorbani, A., Magnusson, M., Souza, A. L., et al. (2015) · Nature Communications · doi:10.1038/ncomms7791 · Cited by 161 · see citing works
Self-citationAortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia
Pase, M. P., Beiser, A., Himali, J. J., Tsao, C. W., Satizábal, C. L., Vasan, R. S., Seshadri, S. S., & Mitchell, G. F. (2016) · Stroke · doi:10.1161/strokeaha.116.013508 · Cited by 158 · see citing works
Self-citationThe Framingham Study. Cigarettes and the development of intermittent claudication.
Wb, K., & Shurtleff, D. (1973) · PubMed · Cited by 153 · see citing works
Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults
Pase, M. P., Himali, J. J., Mitchell, G. F., Beiser, A., Maillard, P., Tsao, C. W., Larson, M. G., DeCarli, C. S., Vasan, R. S., & Seshadri, S. S. (2016) · Hypertension · doi:10.1161/hypertensionaha.115.06610 · Cited by 148 · see citing works
Self-citationMultimarker Approach for the Prediction of Heart Failure Incidence in the Community
Velagaleti, R. S., Gona, P. N., Larson, M. G., Wang, T. J., Levy, D. A., Benjamin, E. J., Selhub, J., Jacques, P. F., Meigs, J. B., Tofler, G. H., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.929661 · Cited by 147 · see citing works
Self-citationMerino, J., Leong, A., Liu, C., Porneala, B., Walford, G. A., von Grotthuss, M., Wang, T. J., Flannick, J. A., Dupuis, J., Levy, D. A., et al. (2018) · Diabetologia · doi:10.1007/s00125-018-4599-x · Cited by 144 · see citing works
Self-citationRelation of Multiple Inflammatory Biomarkers to Incident Atrial Fibrillation
Schnabel, R. B., Larson, M. G., Yamamoto, J. F., Kathiresan, S., Rong, J., Levy, D. A., Keaney, J. F., Wang, T. J., Vasan, R. S., & Benjamin, E. J. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.02.053 · Cited by 143 · see citing works
Self-citationRelation of Central Arterial Stiffness to Incident Heart Failure in the Community
Tsao, C. W., Lyass, A., Larson, M. G., Levy, D. A., Hamburg, N. M., Vita, J. A., Benjamin, E. J., Mitchell, G. F., & Vasan, R. S. (2015) · Journal of the American Heart Association · doi:10.1161/jaha.115.002189 · Cited by 141 · see citing works
Self-citationAortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity
Maillard, P., Mitchell, G. F., Himali, J. J., Beiser, A., Fletcher, E. M., Tsao, C. W., Pase, M. P., Satizábal, C. L., Vasan, R. S., Seshadri, S. S., et al. (2017) · Stroke · doi:10.1161/strokeaha.116.016321 · Cited by 138 · see citing works
Self-citationNiiranen, T., Kalesan, B., Hamburg, N. M., Benjamin, E. J., Mitchell, G. F., & Vasan, R. S. (2016) · Journal of the American Heart Association · doi:10.1161/jaha.116.004271 · Cited by 137 · see citing works
Self-citationLifetime Risk of Coronary Heart Disease by Cholesterol Levels at Selected Ages
Lloyd‐Jones, D. M., Wilson, P. W. F., Larson, M. G., Leip, E. P., Beiser, A., D’Agostino, R. B., Cleeman, J. I., & Levy, D. A. (2003) · Archives of Internal Medicine · doi:10.1001/archinte.163.16.1966 · Cited by 137 · see citing works
Self-citationTan, Z. S., Beiser, A., Fox, C. S., Au, R., Himali, J. J., Debette, S., DeCarli, C. S., Vasan, R. S., Wolf, P. A., & Seshadri, S. S. (2011) · Diabetes Care · doi:10.2337/dc11-0308 · Cited by 135 · see citing works
Self-citationPrevalence, Neurohormonal Correlates, and Prognosis of Heart Failure Stages in the Community
Xanthakis, V., Enserro, D. M., Larson, M. G., Wollert, K. C., Januzzi, J. L., Levy, D. A., Aragam, J. R., Benjamin, E. J., Cheng, S. C., Wang, T. J., et al. (2016) · JACC Heart Failure · doi:10.1016/j.jchf.2016.05.001 · Cited by 135 · see citing works
Self-citationFerencik, M., Pencina, K. M., Liu, T., Ghemigian, K., Baltrusaitis, K., Massaro, J. M., D’Agostino, R. B., O’Donnell, C. J., & Hoffmann, U. (2017) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.117.006592 · Cited by 130 · see citing works
Becoming the Framingham Study 1947–1950
Oppenheimer, G. M. (2005) · American Journal of Public Health · doi:10.2105/ajph.2003.026419 · Cited by 129 · see citing works
Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study
Maillard, P., Mitchell, G. F., Himali, J. J., Beiser, A., Tsao, C. W., Pase, M. P., Satizábal, C. L., Vasan, R. S., Seshadri, S. S., & DeCarli, C. S. (2016) · Stroke · doi:10.1161/strokeaha.116.012949 · Cited by 122 · see citing works
Self-citationPlasma amyloid‐β and risk of Alzheimer's disease in the Framingham Heart Study
Chouraki, V. A., Beiser, A., Younkin, L. H., Preis, S. R., Weinstein, G., Hansson, O., Skoog, I. G., Lambert, J., Au, R., Launer, L. J., et al. (2014) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2014.07.001 · Cited by 120 · see citing works
Fradley, M. G., Larson, M. G., Cheng, S. C., McCabe, E. L., Coglianese, E. E., Shah, R. V., Levy, D. A., Vasan, R. S., & Wang, T. J. (2011) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2011.06.057 · Cited by 119 · see citing works
Self-citationPrimary and subsequent coronary risk appraisal: New results from The Framingham Study
D’Agostino, R. B., Russell, M. W., Huse, D. M., Ellison, R. C., Silbershatz, H., Wilson, P. W. F., & Hartz, S. C. (2000) · American Heart Journal · doi:10.1067/mhj.2000.96469 · Cited by 117 · see citing works
Norton, N., Li, D., Rampersaud, E., Morales, A., Martin, E. R., Zuchner, S. L., Guo, S., Gonzalez, M., Hedges, D. J., Robertson, P. D., et al. (2013) · Circulation Cardiovascular Genetics · doi:10.1161/circgenetics.111.000062 · Cited by 112 · see citing works
Echocardiographic reference values for aortic root size: The Framingham Heart Study
Vasan, R. S., Larson, M. G., Benjamin, E. J., & Levy, D. A. (1995) · Journal of the American Society of Echocardiography · doi:10.1016/s0894-7317(05)80003-3 · Cited by 110 · see citing works
Self-citationA Multi-Marker Approach to Predict Incident CKD and Microalbuminuria
Fox, C. S., Gona, P. N., Larson, M. G., Selhub, J., Tofler, G. H., Hwang, S., Meigs, J. B., Levy, D. A., Wang, T. J., Jacques, P. F., et al. (2010) · Journal of the American Society of Nephrology · doi:10.1681/asn.2010010085 · Cited by 101 · see citing works
Self-citationKaess, B. M., Rong, J., Larson, M. G., Hamburg, N. M., Vita, J. A., Cheng, S. C., Aragam, J., Levy, D. A., Benjamin, E. J., Vasan, R. S., et al. (2016) · Journal of the American Heart Association · doi:10.1161/jaha.115.002693 · Cited by 101 · see citing works
Self-citationA Whole-Blood Transcriptome Meta-Analysis Identifies Gene Expression Signatures of Cigarette Smoking
Huan, T., Joehanes, R., Schurmann, C., Schramm, K., Pilling, L. C., Peters, M. J., Mägi, R., DeMeo, D. L., O’Connor, G. T., Ferrucci, L., et al. (2016) · Human Molecular Genetics · doi:10.1093/hmg/ddw288 · Cited by 97 · see citing works
Self-citationHabitual level of physical activity and risk of coronary heart disease: the Framingham study.
Wb, K. (1967) · PubMed · Cited by 96 · see citing works
Fat Quality and Incident Cardiovascular Disease, All-Cause Mortality, and Cancer Mortality
Rosenquist, K. J., Massaro, J. M., Pedley, A., Long, M. T., Kreger, B. E., Vasan, R. S., Murabito, J. M., Hoffmann, U., & Fox, C. S. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-4296 · Cited by 95 · see citing works
Self-citationWidlansky, M. E., Vita, J. A., Keyes, M. J., Larson, M. G., Hamburg, N. M., Levy, D. A., Mitchell, G. F., Osypiuk, E. W., Vasan, R. S., & Benjamin, E. J. (2007) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2007.03.055 · Cited by 87 · see citing works
Self-citationAndersson, C., Lyass, A., Larson, M. G., Spartano, N. L., Vita, J. A., Benjamin, E. J., Murabito, J. M., Esliger, D., Blease, S. J., Hamburg, N. M., et al. (2015) · Journal of the American Heart Association · doi:10.1161/jaha.114.001528 · Cited by 87 · see citing works
Self-citationFoppa, M., Arora, G., Gona, P. N., Ashrafi, A., Salton, C. J., Yeon, S. B., Blease, S. J., Levy, D. A., O’Donnell, C. J., Manning, W. J., et al. (2016) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.115.003810 · Cited by 86 · see citing works
Self-citationShaikh, A. Y., Wang, N., Yin, X., Larson, M. G., Vasan, R. S., Hamburg, N. M., Magnani, J. W., Ellinor, P. T., Lubitz, S. A., Mitchell, G. F., et al. (2016) · Hypertension · doi:10.1161/hypertensionaha.116.07650 · Cited by 86 · see citing works
Self-citationHistorical Perspectives on the Management of Hypertension
Moser, M. (2006) · Journal of Clinical Hypertension · doi:10.1111/j.1524-6175.2006.05836.x · Cited by 86 · see citing works
Kathiresan, S., Gona, P. N., Larson, M. G., Vita, J. A., Mitchell, G. F., Tofler, G. H., Levy, D. A., Newton‐Cheh, C., Wang, T. J., Benjamin, E. J., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.580233 · Cited by 83 · see citing works
Self-citationVasan, R. S., Benjamin, E. J., & Larson, M. G. (2003) · ACC Current Journal Review · doi:10.1016/s1062-1458(02)01015-2 · Cited by 82 · see citing works
Self-citationAtrial Fibrillation Is Associated With Lower Cognitive Performance in the Framingham Offspring Men
Elias, M. F., Sullivan, L. M., Elias, P. K., Vasan, R. S., D’Agostino, R. B., Seshadri, S., Au, R., Wolf, P. A., & Benjamin, E. J. (2006) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2006.05.009 · Cited by 80 · see citing works
Self-citationADP Platelet Hyperreactivity Predicts Cardiovascular Disease in the FHS (Framingham Heart Study)
Puurunen, M. K., Hwang, S., Larson, M. G., Vasan, R. S., O’Donnell, C. J., Tofler, G. H., & Johnson, A. D. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.118.008522 · Cited by 80 · see citing works
Self-citationAndersson, C., Preis, S. R., Beiser, A., DeCarli, C. S., Wollert, K. C., Wang, T. J., Januzzi, J. L., Vasan, R. S., & Seshadri, S. S. (2015) · Stroke · doi:10.1161/strokeaha.115.009026 · Cited by 78 · see citing works
Self-citationDehghan, A., Bis, J. C., White, C. C., Smith, A. V., Morrison, A. C., Cupples, L. A., Trompet, S., Chasman, D. I., Lumley, T., Völker, U., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0144997 · Cited by 78 · see citing works
Self-citationGenetic Architecture of the Cardiovascular Risk Proteome
Benson, M. D., Yang, Q., Ngo, D., Zhu, Y., Shen, D., Farrell, L. A., Sinha, S., Keyes, M. J., Vasan, R. S., Larson, M. G., et al. (2017) · Circulation · doi:10.1161/circulationaha.117.029536 · Cited by 78 · see citing works
Self-citationGORDON, A. S., Tabor, H. K., Johnson, A. D., Snively, B. M., Assimes, T. L., Auer, P. L., Ioannidis, J. P. A., Peters, U., Robinson, J. G., Sucheston, L. E., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt588 · Cited by 78 · see citing works
Self-citationAtrial fibrillation and cognitive decline in the Framingham Heart Study
Nishtala, A., Piers, R. J., Himali, J. J., Beiser, A., Davis‐Plourde, K. L., Saczynski, J. S., McManus, D. D., Benjamin, E. J., & Au, R. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.09.036 · Cited by 77 · see citing works
Self-citationXanthakis, V., Larson, M. G., Wollert, K. C., Aragam, J. R., Cheng, S. C., Ho, J. E., Coglianese, E. E., Levy, D. A., Colucci, W. S., Felker, G. M., et al. (2013) · Journal of the American Heart Association · doi:10.1161/jaha.113.000399 · Cited by 75 · see citing works
Self-citationAndersson, C., Enserro, D. M., SULLIVAN, L. M., Wang, T. J., Januzzi, J. L., Benjamin, E. J., Vita, J. A., Hamburg, N. M., Larson, M. G., Mitchell, G. F., et al. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.02.013 · Cited by 75 · see citing works
Self-citationYeon, S. B., Salton, C. J., Gona, P. N., Chuang, M. L., Blease, S. J., Han, Y., Tsao, C. W., Danias, P. G., Levy, D. A., O’Donnell, C. J., et al. (2014) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.24649 · Cited by 73 · see citing works
Self-citationAnalysis of a urinary biomarker panel for incident kidney disease and clinical outcomes.
O'Seaghdha, C., Hwang, S.-J., Larson, M., Meigs, J., Vasan, R., & Fox, C. (2013) · Journal of the American Society of Nephrology · doi:10.1681/asn.2013010019 · Cited by 73 · see citing works
Self-citationMultiple Biomarkers and Risk of Clinical and Subclinical Vascular Brain Injury
Pikula, A., Beiser, A., DeCarli, C. S., Himali, J. J., Debette, S., Au, R., Selhub, J., Toffler, G. H., Wang, T. J., Meigs, J. B., et al. (2012) · Circulation · doi:10.1161/circulationaha.110.989145 · Cited by 71 · see citing works
Self-citationAn exome array study of the plasma metabolome
Rhee, E. P., Yang, Q., Yu, B., Liu, X., Cheng, S. C., Deik, A., Pierce, K. A., Bullock, K. H., Ho, J. E., Levy, D. A., et al. (2016) · Nature Communications · doi:10.1038/ncomms12360 · Cited by 71 · see citing works
Self-citationAggregate penetrance of genomic variants for actionable disorders in European and African Americans
Natarajan, P., Gold, N. B., Bick, A. G., McLaughlin, H. M., Kraft, P. L., Rehm, H. L., Peloso, G. M., Wilson, J. G., Correa, A., Seidman, J. G., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aag2367 · Cited by 70 · see citing works
Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis
Natarajan, P., Bis, J. C., Bielak, L. F., Cox, A. J., Dörr, M., Feitosa, M. F., Franceschini, N., Guo, X., Hwang, S.-J., Isaacs, A., et al. (2016) · Circulation: Cardiovascular Genetics · doi:10.1161/circgenetics.116.001572 · Cited by 66 · see citing works
Plasma Brain Natriuretic Peptide Levels and Blood Pressure Tracking in the Framingham Heart Study
Freitag, M., Larson, M. G., Levy, D. A., Benjamin, E. J., Wang, T. J., Leip, E. P., Wilson, P. W. F., & Vasan, R. S. (2003) · Hypertension · doi:10.1161/01.hyp.0000061116.20490.8d · Cited by 65 · see citing works
Self-citationMethylome-wide Association Study of Atrial Fibrillation in Framingham Heart Study
Lin, H., Yin, X., Xie, Z., Lunetta, K. L., Lubitz, S. A., Larson, M. G., Ko, D., Magnani, J. W., Mendelson, M., Liu, C., et al. (2017) · Scientific Reports · doi:10.1038/srep40377 · Cited by 62 · see citing works
Self-citationChuang, M. L., Gona, P. N., Hautvast, G. L. T. F., Salton, C. J., Breeuwer, M. M., O’Donnell, C. J., & Manning, W. J. (2013) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.24239 · Cited by 59 · see citing works
Kannel, W. B. (1976) · BMJ · doi:10.1136/bmj.2.6046.1255-a · Cited by 57 · see citing works
Moselewski, F., O’Donnell, C. J., Achenbach, S. S., Ferencik, M., Massaro, J., Nguyen, A., Cury, R. C., Abbara, S., Jang, I., Brady, T. J., et al. (2005) · Circulation · doi:10.1161/circulationaha.104.489781 · Cited by 57 · see citing works
Relation of Visceral Adiposity to Circulating Natriuretic Peptides in Ambulatory Individuals
Cheng, S. C., Fox, C. S., Larson, M. G., Massaro, J. M., McCabe, E. L., Khan, A. M., Levy, D. A., Hoffmann, U., O’Donnell, C. J., Miller, K. K., et al. (2011) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2011.05.033 · Cited by 56 · see citing works
Self-citationDissecting the Roles of MicroRNAs in Coronary Heart Disease via Integrative Genomic Analyses
Huan, T., Rong, J., Tanrıverdi, K., Meng, Q., Bhattacharya, A., McManus, D. D., Joehanes, R., Assimes, T. L., McPherson, R., Samani, N. J., et al. (2015) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.114.305176 · Cited by 56 · see citing works
Self-citationCirculating biomarkers and incident ischemic stroke in the Framingham Offspring Study
Shoamanesh, A., Preis, S. R., Beiser, A., Kase, C. S., Wolf, P. A., Vasan, R. S., Benjamin, E. J., Seshadri, S. S., & Romero, J. R. (2016) · Neurology · doi:10.1212/wnl.0000000000003115 · Cited by 55 · see citing works
Self-citationTsao, C. W., Preis, S. R., Peloso, G. M., Hwang, S., Kathiresan, S., Fox, C. S., Cupples, L. A., Hoffmann, U., & O’Donnell, C. J. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.09.007 · Cited by 53 · see citing works
Lee, J., Pedley, A., Hoffmann, U., Massaro, J. M., Keaney, J. F., Vasan, R. S., & Fox, C. S. (2016) · Journal of the American Heart Association · doi:10.1161/jaha.115.002545 · Cited by 52 · see citing works
Self-citationMurabito, J. M., Pedley, A., Massaro, J. M., Vasan, R. S., Esliger, D., Blease, S. J., Hoffman, U., & Fox, C. S. (2015) · Journal of the American Heart Association · doi:10.1161/jaha.114.001379 · Cited by 48 · see citing works
Self-citationINFLAMMATORY MARKERS AND THE RISK OF ALZHEIMER DISEASE: THE FRAMINGHAM STUDY
Tobinick, E. L. (2008) · Neurology · doi:10.1212/01.wnl.0000307660.86647.7b · Cited by 47 · see citing works
Lauer, M. S., Larson, M. G., Evans, J. C., & Levy, D. A. (1999) · American Heart Journal · doi:10.1016/s0002-8703(99)70415-1 · Cited by 46 · see citing works
Self-citationCirculating Adipokines and Vascular Function
Zachariah, J. P. V., Hwang, S., Hamburg, N. M., Benjamin, E. J., Larson, M. G., Levy, D. A., Vita, J. A., SULLIVAN, L. M., Mitchell, G. F., & Vasan, R. S. (2015) · Hypertension · doi:10.1161/hypertensionaha.115.05949 · Cited by 42 · see citing works
Self-citationWhole Exome Sequencing in Atrial Fibrillation
Lubitz, S. A., Brody, J. A., Bihlmeyer, N. A., Roselli, C., Weng, L.-C. C., Christophersen, I. E., Alonso, Á., Boerwinkle, E., Gibbs, R. A., Bis, J. C., et al. (2016) · PLoS Genetics · doi:10.1371/journal.pgen.1006284 · Cited by 40 · see citing works
Self-citationEffect of Phosphodiesterase Inhibition on Insulin Resistance in Obese Individuals
Ho, J. E., Arora, P., Walford, G. A., Ghorbani, A., Guanaga, D. P., Dhakal, B. P., Nathan, D. I., Buys, E. S., Florez, J. C., Newton‐Cheh, C., et al. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.114.001001 · Cited by 39 · see citing works
Association of Parental Hypertension With Arterial Stiffness in Nonhypertensive Offspring
Andersson, C., Quiroz, R., Enserro, D. M., Larson, M. G., Hamburg, N. M., Vita, J. A., Levy, D. A., Benjamin, E. J., Mitchell, G. F., & Vasan, R. S. (2016) · Hypertension · doi:10.1161/hypertensionaha.116.07426 · Cited by 38 · see citing works
Self-citationHwang, S., Onuma, O. K., Massaro, J. M., Zhang, X., Fu, Y., Hoffmann, U., Fox, C. S., & O’Donnell, C. J. (2018) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.117.006209 · Cited by 38 · see citing works
Preis, S. R., Hwang, S., Fox, C. S., Massaro, J. M., Levy, D. A., Hoffmann, U., & O’Donnell, C. J. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.02.020 · Cited by 30 · see citing works
Self-citationBimodal Aldosterone Distribution in Low-Renin Hypertension
Adlin, E. V., Braitman, L. E., & Vasan, R. S. (2013) · American Journal of Hypertension · doi:10.1093/ajh/hpt091 · Cited by 29 · see citing works
Self-citationMetabolic Predictors of Change in Vascular Function
Zachariah, J. P. V., Rong, J., Larson, M. G., Hamburg, N. M., Benjamin, E. J., Vasan, R. S., & Mitchell, G. F. (2017) · Hypertension · doi:10.1161/hypertensionaha.117.10054 · Cited by 28 · see citing works
Self-citationConsent for genetic research in the Framingham Heart Study
Levy, D. A., Splansky, G. L., Strand, N. K., Atwood, L. D., Benjamin, E. J., Blease, S. J., Cupples, L. A., D’Agostino, R. B., Fox, C. S., Kelly‐Hayes, M., et al. (2010) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.33377 · Cited by 27 · see citing works
Self-citationMetabolite Signatures of Metabolic Risk Factors and their Longitudinal Changes
Yin, X., Subramanian, S., Willinger, C. M., Chen, G., Juhász, P., Courchesne, P. L., Chen, B. H., Li, X., Hwang, S., Fox, C. S., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-2555 · Cited by 24 · see citing works
Self-citationJohnson, A. D., Bhimavarapu, A., Benjamin, E. J., Fox, C. S., Levy, D. A., Jarvik, G. P., & O’Donnell, C. J. (2010) · Genetics in Medicine · doi:10.1097/gim.0b013e3181e1e2a9 · Cited by 23 · see citing works
Self-citationThe association between sleep-disordered breathing and aortic stiffness in a community cohort
Chami, H. A., Vasan, R. S., Larson, M. G., Benjamin, E. J., Mitchell, G. F., & Gottlieb, D. J. (2015) · Sleep Medicine · doi:10.1016/j.sleep.2015.11.009 · Cited by 21 · see citing works
Self-citation
Flagged first, then by citations
4 of the 210 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
The changing landscape of atherosclerosis
Libby, P. (2021) · Nature · doi:10.1038/s41586-021-03392-8 · Cited by 2,873 · see citing works
Neutrophils as regulators of cardiovascular inflammation
Silvestre-Roig, C., Braster, Q., Ortega‐Gómez, A., & Soehnlein, O. (2020) · Nature Reviews Cardiology · doi:10.1038/s41569-019-0326-7 · Cited by 608 · see citing works
Insulin resistance and cardiovascular disease
Kosmas, C. E., Bousvarou, M. D., Kostara, C. E., Papakonstantinou, E. J., Salamou, E., & Guzman, E. (2023) · Journal of International Medical Research · doi:10.1177/03000605231164548 · Cited by 413 · see citing works
Epigenetic regulation in cardiovascular disease: mechanisms and advances in clinical trials
Shi, Y., Zhang, H., Huang, S., Yin, L., Wang, F., Luo, P., & Huang, H. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01055-2 · Cited by 366 · see citing works
Pre-Analytical Factors that Affect Metabolite Stability in Human Urine, Plasma, and Serum: A Review
Stevens, V. L., Hoover, E., Wang, Y., & Zanetti, K. A. (2019) · Metabolites · doi:10.3390/metabo9080156 · Cited by 189 · see citing works
Digital healthcare: the future
Butcher, C. J., & Hussain, W. (2022) · Future Healthcare Journal · doi:10.7861/fhj.2022-0046 · Cited by 157 · see citing works
Incidence of Transient Ischemic Attack and Association With Long-term Risk of Stroke
Lioutas, V., Ivan, C. S., Himali, J. J., Aparicio, H. J., Leveille, T., Romero, J. R., Beiser, A., & Seshadri, S. S. (2021) · JAMA · doi:10.1001/jama.2020.25071 · Cited by 137 · see citing works
Lioutas, V., Beiser, A., Aparicio, H. J., Himali, J. J., Selim, M. H., Romero, J. R., & Seshadri, S. S. (2020) · JAMA Neurology · doi:10.1001/jamaneurol.2020.1512 · Cited by 117 · see citing works
Minno, A. D., Gelzo, M., Caterino, M., Costanzo, M., Ruoppolo, M., & Castaldo, G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23095213 · Cited by 118 · see citing works
Exposome in ischaemic heart disease: beyond traditional risk factors
Montone, R. A., Camilli, M., Calvieri, C., Magnani, G., Bonanni, A., Bhatt, D. L., Rajagopalan, S., Crea, F., & Niccoli, G. (2024) · European Heart Journal · doi:10.1093/eurheartj/ehae001 · Cited by 111 · see citing works
Optimized Ensemble Learning Approach with Explainable AI for Improved Heart Disease Prediction
Mienye, I. D., & Jere, N. R. (2024) · Information · doi:10.3390/info15070394 · Cited by 118 · see citing works
Yoram Vodovotz, B., Barnard, N. D., Hu, F. B., Jakicic, J. M., Lianov, L. S., Loveland, D., Buysse, D. J., Szigethy, E., Finkel, T., Sowa, G., et al. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.585744 · Cited by 108 · see citing works
Andersson, C., Nayor, M. G., Tsao, C. W., Levy, D. A., & Vasan, R. S. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2021.01.059 · Cited by 94 · see citing works
Self-citationAmini, S., Hao, B., Zhang, L., Song, M., Gupta, A., Karjadi, C., Kolachalama, V. B., Au, R., & Paschalidis, I. C. (2023) · Alzheimer's & Dementia · doi:10.1002/alz.12721 · Cited by 76 · see citing works
Amini, S., Hao, B., Yang, J., Karjadi, C., Kolachalama, V. B., Au, R., & Paschalidis, I. C. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.13886 · Cited by 79 · see citing works
Yannas, D., Frizza, F., Vignozzi, L., Corona, G., Maggi, M., & Rastrelli, G. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10102221 · Cited by 68 · see citing works
Kim, J. O., Jeong, Y.-S., Kim, J. H., Lee, J., Park, D., & Kim, H.-S. (2021) · Diagnostics · doi:10.3390/diagnostics11060943 · Cited by 70 · see citing works
Endothelial Dysfunction in Obesity and Therapeutic Targets
Engin, A. (2024) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-63657-8_17 · Cited by 71 · see citing works
DNA methylation and gene expression integration in cardiovascular disease
Palou-Márquez, G., Subirana, I., Nonell, L., Fernández‐Sanlés, A., & Elosúa, R. (2021) · Clinical Epigenetics · doi:10.1186/s13148-021-01064-y · Cited by 61 · see citing works
Goals in Nutrition Science 2020-2025
Bassaganya-Riera, J., Berry, E. M., Blaak, E. E., Burlingame, B., le Coutre, J., van Eden, W., El‐Sohemy, A., German, J. B., Knorr, D., Lacroix, C., et al. (2021) · Frontiers in Nutrition · doi:10.3389/fnut.2020.606378 · Cited by 65 · see citing works
Amini, S., Zhang, L., Hao, B., Gupta, A., Song, M., Karjadi, C., Lin, H., Kolachalama, V. B., Au, R., & Paschalidis, I. C. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210299 · Cited by 59 · see citing works
Aging Biomarker Consortium, Zhang, L., Guo, J., Liu, Y., Sun, S., Liu, B., Yang, Q., Tao, J., Tian, X.-L., Pu, J., et al. (2023) · Life Medicine · doi:10.1093/lifemedi/lnad033 · Cited by 60 · see citing works
Omotehinwa, T. O., Oyewola, D. O., & Moung, E. G. (2024) · Informatics and Health · doi:10.1016/j.infoh.2024.06.001 · Cited by 52 · see citing works
Human genetics and its impact on cardiovascular disease
Tada, H., Fujino, N., Hayashi, K., Kawashiri, M., & Takamura, M. (2021) · Journal of Cardiology · doi:10.1016/j.jjcc.2021.09.005 · Cited by 51 · see citing works
The IL-1 Family and Its Role in Atherosclerosis
González, L., Rivera, K., Andía, M. E., & Martı́nez-Rodrı́guez, G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010017 · Cited by 49 · see citing works
Duffy, E. Y., Ashen, M. D., Blumenthal, R. S., Davis, D. M., Gulati, M., Blaha, M. J., Michos, E. D., Nasir, K., & Cainzos‐Achirica, M. (2021) · Clinical Cardiology · doi:10.1002/clc.23555 · Cited by 48 · see citing works
Exploring Artificial Intelligence in Anesthesia: A Primer on Ethics, and Clinical Applications
Cascella, M., Tracey, M. C., Petrucci, E., & Bignami, E. G. (2023) · Surgeries · doi:10.3390/surgeries4020027 · Cited by 47 · see citing works
Diabetic Cardiomyopathy: 2023 Update by the International Multidisciplinary Board of Experts
Арманович, А. А., Fogacci, F., Вачиковна, П. Н., Kakrurskiy, L., Коган, Е. А., Urazova, O. I., Kobalava, Z. D., Михалева, Л. М., Vandysheva, R. A., Zarina, G., et al. (2023) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2023.102052 · Cited by 52 · see citing works
Xu, C., Zhang, P., & Cao, Z. (2022) · EClinicalMedicine · doi:10.1016/j.eclinm.2022.101329 · Cited by 43 · see citing works
Zhao, X., Sui, Y., Ruan, X., Wang, X., He, K., Dong, W., Qu, H., & Fang, X. (2022) · Clinical Epigenetics · doi:10.1186/s13148-022-01232-8 · Cited by 42 · see citing works
Diet, Pace of Biological Aging, and Risk of Dementia in the Framingham Heart Study
Thomas, A., Ryan, C. P., Caspi, A., Liu, Z., Moffitt, T. E., Sugden, K., Zhou, J., Belsky, D. W., & Gu, Y. (2024) · Annals of Neurology · doi:10.1002/ana.26900 · Cited by 42 · see citing works
Tragni, E., Vigna, L., Ruscica, M., Macchi, C., Casula, M., Santelia, A., Catapano, A. L., & Magni, P. (2021) · Nutrients · doi:10.3390/nu13061804 · Cited by 41 · see citing works
Chu, H., Chen, L., Yang, X., Qiu, X., Qiao, Z., Song, X., Zhao, E., Zhou, J., Zhang, W., Mehmood, A., et al. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.645418 · Cited by 40 · see citing works
Modeling genome-wide by environment interactions through omnigenic interactome networks
Wang, H., Ye, M., Fu, Y., Dong, A., Zhang, M., Feng, L., Zhu, X., Bo, W., Jiang, L., Griffin, C. H., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.109114 · Cited by 39 · see citing works
Thomas, J., Burkhardt, H. A., Chaudhry, S., Ngo, A. D., Sharma, S., Zhang, L., Au, R., & Ghomi, R. H. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-190783 · Cited by 37 · see citing works
Targeting flavonoids on modulation of metabolic syndrome
Neri-Numa, I. A., Cazarin, C. B. B., Ruiz, A. L. T. G., Paulino, B. N., Molina, G., & Pastore, G. M. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104132 · Cited by 38 · see citing works
Serotonin‐Affecting Antidepressant Use in Relation to Platelet Reactivity
Grech, J., Chan, M. V., Ochin, C., Lachapelle, A., Thibord, F., Schneider, Z., Nkambule, B. B., Armstrong, P. C. J., de Melendez, C. W., Tucker, K. L., et al. (2021) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt.2517 · Cited by 35 · see citing works
Self-citationKereliuk, S. M., & Dolinsky, V. W. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084467 · Cited by 34 · see citing works
“Over its 74-year length, the Framingham Heart Study has demonstrated that hypertension, coronary artery disease, cardiac hypertension and diabetes are cardiovascular risk factors associated with the future development of heart failure [2,3].”
BackgroundMethodYi, Y., Luo, Q., Chen, J., Chen, Z., Aydemir, H. A., Chen, P., Tang, J., Luo, F., & Fang, Z. (2025) · Lipids in Health and Disease · doi:10.1186/s12944-025-02551-4 · Cited by 34 · see citing works
Unlocking the Pharmacological Potential of Myricetin Against Various Pathogenesis
Almatroodi, S. A., & Rahmani, A. H. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26094188 · Cited by 35 · see citing works
Inflammation in Heart Failure—Future Perspectives
Arvunescu, A. M., Ionescu, R. F., Creţoiu, S. M., Dumitrescu, S. I., Zaharia, O., & Nanea, I. T. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12247738 · Cited by 37 · see citing works
Li, X., Liu, X., Deng, X., & Fan, Y. (2022) · Biomedicines · doi:10.3390/biomedicines10092157 · Cited by 32 · see citing works
Fazel, S., Vazquez-Montes, M., Molero, Y., Runeson, B., D'Onofrio, B. M., Larsson, H., Lichtenstein, P., Walker, J., Sharpe, M., & Fanshawe, T. R. (2023) · BMJ Mental Health · doi:10.1136/bmjment-2023-300673 · Cited by 31 · see citing works
Scollard, P., Choi, S., Lee, M. L., Mukherjee, S., Trittschuh, E. H., Sanders, R. E., Gibbons, L. E., Joshi, P. S., Devine, S., Au, R., et al. (2023) · Neuropsychology · doi:10.1037/neu0000828 · Cited by 32 · see citing works
Galli, M., Abbate, A., Bonaca, M. P., Crea, F., Forte, M., Frati, G., Gaudino, M. F. L., Gibson, C. M., Gorog, D. A., Mehran, R., et al. (2026) · Nature Reviews Cardiology · doi:10.1038/s41569-026-01249-z · Cited by 35 · see citing works
Family History of Modifiable Risk Factors and Association With Future Cardiovascular Disease
TAYLOR, C. N., Wang, D., Larson, M. G., Lau, E. S., Benjamin, E. J., D’Agostino, R. B., Vasan, R. S., Levy, D. A., Cheng, S. C., & Ho, J. E. (2023) · Journal of the American Heart Association · doi:10.1161/jaha.122.027881 · Cited by 29 · see citing works
Self-citationDrugs for dyslipidaemia: the legacy effect of the Scandinavian Simvastatin Survival Study (4S)
Strandberg, T. E., Kovanen, P. T., Lloyd‐Jones, D. M., Raal, F. J., Santos, R. D., & Watts, G. F. (2024) · The Lancet · doi:10.1016/s0140-6736(24)02089-0 · Cited by 29 · see citing works
Zuo, S., Wang, G., Han, Q., Xiao, H., Santos, H. O., Rodriguez, D. A., Khani, V., & Tang, J. (2020) · Complementary Therapies in Medicine · doi:10.1016/j.ctim.2020.102450 · Cited by 29 · see citing works
Neytchev, O., Erlandsson, H., Witasp, A., Nordfors, L., Qureshi, A. R., Iseri, K., Morohoshi, H., Selman, C., Ebert, T., Kublickiene, K. R., et al. (2023) · Journal of Internal Medicine · doi:10.1111/joim.13724 · Cited by 29 · see citing works
A Novel BrainHealth Index Prototype Improved by Telehealth-Delivered Training During COVID-19
Chapman, S. B., Fratantoni, J. M., Robertson, I. H., D’Esposito, M., Ling, G. S. F., Zientz, J., Vernon, S., Venza, E. E., Cook, L. G., Tate, A., et al. (2021) · Frontiers in Public Health · doi:10.3389/fpubh.2021.641754 · Cited by 27 · see citing works
Sun, J., Xie, Z., Wu, Y., Liu, X., Ma, J., Dong, Y., Liu, C., Ye, M., & Zhu, W. (2023) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2023.07.011 · Cited by 29 · see citing works
Bontempo, P., Capasso, L., Masi, L. D., Nebbioso, A., & Rigano, D. (2024) · Nutrients · doi:10.3390/nu16152399 · Cited by 27 · see citing works
Paljärvi, T., Herttua, K., Taipale, H. T., Lähteenvuo, M., Tanskanen, A. J., Fazel, S., & Tiihonen, J. (2023) · BMJ Mental Health · doi:10.1136/bmjment-2023-300700 · Cited by 27 · see citing works
Shim, J. K., Bentz, M., Vasquez, E. E., Jeske, M., Saperstein, A., Fullerton, S. M., Foti, N., McMahon, C. E., & Lee, S. S. (2022) · Social Science & Medicine · doi:10.1016/j.socscimed.2022.115132 · Cited by 23 · see citing works
Park, J. E., JebaMercy, G., Pazhanchamy, K., Guo, X., Ngan, S. C., Liou, K. C. K., Lynn, S. E., Ng, S. S., Meng, W., Lim, S. C., et al. (2021) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2021.03.020 · Cited by 24 · see citing works
Gaps and opportunities in sepsis translational research
Marshall, J. C., & Leligdowicz, A. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2022.104387 · Cited by 26 · see citing works
Neohesperidin inhibits cardiac remodeling induced by Ang II in vivo and in vitro
Zhang, J., Fu, X., Li, Y., Wen, H., Zhang, L., Liu, F., Lou, Y., Yang, Q., & Ding, Y. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110364 · Cited by 24 · see citing works
Cruz, L. A., Bailey, J. N. C., & Crawford, D. C. (2023) · Annual Review of Biomedical Data Science · doi:10.1146/annurev-biodatasci-122220-113250 · Cited by 22 · see citing works
Suo, J., Gan, Y., Xie, Y., Xu, S., Wang, J., Chen, D., Chen, L., Deng, L., Feng, S., Han, J. J., et al. (2023) · Life Medicine · doi:10.1093/lifemedi/lnad045 · Cited by 22 · see citing works
Harmonization-Information Trade-Offs for Sharing Individual Participant Data in Biomedicine
Espin, A. T. (2022) · Harvard Data Science Review · doi:10.1162/99608f92.a9717b34 · Cited by 22 · see citing works
Frederiksen, T. C., Benjamin, E. J., Trinquart, L., Lin, H., Dahm, C. C., Christiansen, M. K., Jensen, H. K., Preis, S. R., & Kornej, J. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.032226 · Cited by 22 · see citing works
Self-citationThe Role of Inflammation as a Preponderant Risk Factor in Cardiovascular Diseases
García, R. D., Asensio, J. A., Perdicaro, D. J., & Peral, M. D. L. Á. (2022) · Current Vascular Pharmacology · doi:10.2174/1570161120666220201160038 · Cited by 20 · see citing works
Petrenya, N., Hopstock, L. A., Holde, G. E., Oscarson, N., & Jönsson, B. (2022) · Journal of Periodontology · doi:10.1002/jper.22-0004 · Cited by 19 · see citing works
Pashek, R., Nkambule, B. B., Chan, M. V., Thibord, F., Lachapelle, A., Cunha, J., Chen, M., & Johnson, A. D. (2023) · International Journal of Epidemiology · doi:10.1093/ije/dyad099 · Cited by 19 · see citing works
Self-citationEconomic evaluation of nutrition interventions: Does one size fit all?
Fattore, G., Federici, C., Drummond, M., Mazzocchi, M., Detzel, P., Hutton, Z. V., & Shankar, B. (2021) · Health Policy · doi:10.1016/j.healthpol.2021.06.009 · Cited by 20 · see citing works
The characteristics of risk factors in Chinese young women with acute coronary syndrome
Liu, R., Xu, F., Zhou, Y., & Liu, T. (2020) · BMC Cardiovascular Disorders · doi:10.1186/s12872-020-01577-z · Cited by 18 · see citing works
Leming, M., Das, S., & Im, H. (2022) · Artificial Intelligence in Medicine · doi:10.1016/j.artmed.2022.102309 · Cited by 18 · see citing works
Choi, J. Y., Kim, J. Y., Kwon, H., Choi, H. J., Kim, S. H., Kim, S., Lee, J. B., & Park, J. E. (2022) · Scientific Reports · doi:10.1038/s41598-022-25654-9 · Cited by 18 · see citing works
Cardiovascular disease in children with chronic kidney disease
Kouri, A. M., & Rheault, M. N. (2021) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0000000000000684 · Cited by 18 · see citing works
Kokubo, Y., Watanabe, M., Higashiyama, A., & Honda-Kohmo, K. (2020) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.ed134 · Cited by 18 · see citing works
Alcohol consumption and epigenetic age acceleration across human adulthood
Wang, M., Li, Y., Lai, M. M., Nannini, D. R., Hou, L., Joehanes, R., Huan, T., Levy, D. A., Ma, J., & Liu, C. (2023) · Aging · doi:10.18632/aging.205153 · Cited by 17 · see citing works
Self-citationObstructive Sleep Apnea, Platelet Aggregation, and Cardiovascular Risk
Kovbasyuk, Z., Ramos‐Cejudo, J., Parekh, A., Bubu, O. M., Ayappa, I. A., Varga, A. W., Chen, M., Johnson, A. D., Gutiérrez‐Jiménez, E., Rapoport, D. M., et al. (2024) · Journal of the American Heart Association · doi:10.1161/jaha.123.034079 · Cited by 17 · see citing works
Self-citationRisk factor-based subphenotyping of heart failure in the community
Andersson, C., Lyass, A., Xanthakis, V., Larson, M. G., Mitchell, G. F., Cheng, S. C., & Vasan, R. S. (2019) · PLoS ONE · doi:10.1371/journal.pone.0222886 · Cited by 17 · see citing works
Self-citationMehrabani-Zeinabad, K., Feizi, A., Sadeghi, M., Roohafza, H., Talaei, M., & Sarrafzadegan, N. (2023) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-023-02169-5 · Cited by 16 · see citing works
Matching science to reality: how to deploy a participant-driven digital brain health platform
Anda‐Duran, I. D., Hwang, P. H., Popp, Z., Low, S., Ding, H., Rahman, S., Igwe, A., Kolachalama, V. B., Lin, H., & Au, R. (2023) · Frontiers in Dementia · doi:10.3389/frdem.2023.1135451 · Cited by 14 · see citing works
Chen, T., Chen, T., Xu, W., Liang, S., Xu, F., Liang, D., Li, X., Zeng, C., Xie, G., & Liu, Z. (2024) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.0000000000000471 · Cited by 16 · see citing works
Recent advances in data-driven fusion of multi-modal imaging and genomics for precision medicine
Wang, S., Liu, M., Li, Y., Zhang, X., Sun, M., Wang, Z., Li, R., Li, Q., Li, Q., He, Y., et al. (2024) · Information Fusion · doi:10.1016/j.inffus.2024.102738 · Cited by 17 · see citing works
Huang, Y.-T., Ho, L., Hsu, H., Tu, Y., & Chien, K. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.832614 · Cited by 15 · see citing works
Arena, R. A., Pronk, N. P., Laddu, D., Faghy, M. A., Bond, S., & Lavie, C. J. (2023) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2023.02.010 · Cited by 15 · see citing works
Naguib, Y. M., Samaka, R. M., Rizk, M. S., Ameen, O., & Motawea, S. M. (2021) · Cardiovascular Diabetology · doi:10.1186/s12933-021-01259-w · Cited by 15 · see citing works
Chronic kidney disease and dementia: an epidemiological perspective
Ikram, M. A. (2025) · Nature Reviews Nephrology · doi:10.1038/s41581-025-00967-w · Cited by 17 · see citing works
Fazel, S., Sariaslan, A., & Fanshawe, T. R. (2022) · European Journal on Criminal Policy and Research · doi:10.1007/s10610-022-09520-y · Cited by 16 · see citing works
Fan, P., Zhang, S., Wang, W., Yang, Z., Tan, W., Li, S., Zhu, C., Hu, D., Zhou, X., Tian, Z., et al. (2022) · Frontiers in Public Health · doi:10.3389/fpubh.2022.996169 · Cited by 14 · see citing works
Alcohol consumption as a socially contagious phenomenon in the Framingham Heart Study social network
van den Ende, M. W. J., van der Maas, H. L. J., Epskamp, S., & Lees, M. (2024) · Scientific Reports · doi:10.1038/s41598-024-54155-0 · Cited by 16 · see citing works
Boutilier, J. J., & Chan, T. C. Y. (2023) · INFORMS Transactions on Education · doi:10.1287/ited.2021.0256 · Cited by 14 · see citing works
Wang, K., Guo, K., Ji, Z., Liu, Y., Chen, F., Wu, S., Zhang, Q., Yao, Y., & Zhou, Q. (2022) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2022.62 · Cited by 13 · see citing works
Wang, C., Shi, Z., Li, Y., Xia, X., Kuang, X., Qian, S., Xue, L., Lan, L., Wu, Y., Zhang, N., et al. (2023) · Phenomics · doi:10.1007/s43657-022-00083-w · Cited by 13 · see citing works
M6A modification in cardiovascular disease: With a focus on programmed cell death
Li, W., Liu, Y., Xu, R., Zong, Y., He, L., Hu, J., & Li, G. (2023) · Genes & Diseases · doi:10.1016/j.gendis.2023.05.023 · Cited by 13 · see citing works
Blood DNA methylation signature for incident dementia: Evidence from longitudinal cohorts
Zhang, W., Young, J. I., Gomez, L., Schmidt, M. A., Lukacsovich, D., Kunkle, B. W., Chen, X. S., Martin, E. R., & Wang, L. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.14496 · Cited by 14 · see citing works
Lara-Abelenda, F. J., Chushig-Muzo, D., Peiro-Corbacho, P., Gómez-Martínez, V., Wägner, A. M., Granja, C., & Soguero-Ruíz, C. (2025) · Journal of Biomedical Informatics · doi:10.1016/j.jbi.2025.104821 · Cited by 15 · see citing works
Examine the public health impacts of functional somatic disorders using the DanFunD study
Jørgensen, T., Dantoft, T. M., Petersen, M. W., Benros, M. E., Poulsen, C. H., Eplov, L. F., Gormsen, L. K., Frostholm, L., Carstensen, T. B. W., Eliasen, M., et al. (2022) · Scandinavian Journal of Public Health · doi:10.1177/14034948221122886 · Cited by 13 · see citing works
Dhaynaut, M., Grashow, R. G., Normandin, M. D., Wu, O., Marengi, D. A., Terry, D. P., Sanchez, J. S., Weisskopf, M. G., Speizer, F. E., Taylor, H. A., et al. (2023) · Journal of Neurotrauma · doi:10.1089/neu.2022.0454 · Cited by 12 · see citing works
Cardiovascular Disease in Anti-neutrophil Cytoplasm Antibody-Associated Vasculitis
Sayer, M., Chapman, G. B., Thomas, M., & Dhaun, N. (2023) · Current Rheumatology Reports · doi:10.1007/s11926-023-01123-8 · Cited by 13 · see citing works
Moncusí, M. P., Elhussein, L., Delmestri, A., Cooper, C. C., Moayyeri, A., Libanati, C. R., Tóth, E., Prieto‐Alhambra, D., & Khalid, S. (2020) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.4648 · Cited by 13 · see citing works
Gene Regulatory Networks in Coronary Artery Disease
Cheng, J. Y., Cheng, M., Lusis, A. J., & Yang, X. (2023) · Current Atherosclerosis Reports · doi:10.1007/s11883-023-01170-7 · Cited by 11 · see citing works
Using psychosis biotypes and the Framingham model for parsing psychosis biology
Tamminga, C. A., Pearlson, G. D., Gershon, E. S., Keedy, S., Hudgens‐Haney, M. E., Ivleva, E. I., Parker, D., McDowell, J. E., & Clementz, B. A. (2022) · Schizophrenia Research · doi:10.1016/j.schres.2022.01.018 · Cited by 10 · see citing works
Chen, G., Shriner, D., Zhang, J., Zhou, J., Adikaram, P. R., Doumatey, A. P., Bentley, A. R., Adeyemo, A., & Rotimi, C. N. (2022) · PLoS ONE · doi:10.1371/journal.pone.0269378 · Cited by 11 · see citing works
Clarke, G. D., Li, J., Kuo, A. H., Moody, A. J., & Nathanielsz, P. W. (2020) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174420001233 · Cited by 11 · see citing works
Almidani, L., Sabharwal, J., Shahidzadeh, A., Martinez, A. D. C., Ting, S. J., Vaidya, B., Jiang, X., Kowalczyk, T., Beiser, A., Sobrin, L., et al. (2024) · Ophthalmology Science · doi:10.1016/j.xops.2024.100549 · Cited by 10 · see citing works
Yuda, E., Kaneko, I., & Hirahara, D. (2025) · Applied Sciences · doi:10.3390/app15158671 · Cited by 12 · see citing works
- Authors
- Andersson, C., Johnson, A. D., Benjamin, E. J., Levy, D., & Vasan, R. S.
- Affiliations
- Boston University (US)
- National Institutes of Health (US)
- Corresponding author
- Andersson, Charlotte
- Vasan, Ramachandran S.
- Venue
- Nature Reviews Cardiology
- Published
- 2019-05-07
- Volume
- 16
- Issue
- 11
- Pages
- 687-698
- ISSN
- 1759-5002 (ISSN-L)
- 1759-5010
- OpenAlex
- W2944646092
- Cited by
- 305
- References
- 210
- Citations by year
- 2026: 33 · 2025: 60 · 2024: 48 · 2023: 51 · 2022: 46 · 2021: 40 · 2020: 24 · 2019: 2
- FWCI
- 5.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nature Reviews Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Department of Health and Human Services
- American Heart Association
- Evans Medical Foundation
- National Institutes of Health
- National Heart, Lung, and Blood Institute
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Keywords
- Framingham Heart Study, coronary artery disease, cardiovascular risk factors, risk prediction algorithm, hypertension, hypercholesterolemia, left ventricular hypertrophy, subclinical cardiovascular disease, multi-omics profiling, longitudinal cohort
- MeSH terms
- Cardiovascular Diseases, Coronary Artery Disease, Data Collection, Echocardiography, Exercise Test, Humans, Longitudinal Studies, Magnetic Resonance Imaging, Manometry, Phenotype, Population Surveillance, Risk Factors, Tomography, X-Ray Computed, Genomics, History, 20th Century, History, 21st Century
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
