Cannabinoids and the expanded endocannabinoid system in neurological disorders

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

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Molecular characterization of a peripheral receptor for cannabinoids

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Structure of a cannabinoid receptor and functional expression of the cloned cDNA

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Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

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Determination and characterization of a cannabinoid receptor in rat brain

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2-Arachidonoylgylcerol: A Possible Endogenous Cannabinoid Receptor Ligand in Brain

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Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

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Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome

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Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses

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Microglial and macrophage polarization—new prospects for brain repair

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Brain monoglyceride lipase participating in endocannabinoid inactivation

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CB1 Cannabinoid Receptors and On-Demand Defense Against Excitotoxicity

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A Comprehensive Profile of Brain Enzymes that Hydrolyze the Endocannabinoid 2-Arachidonoylglycerol

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Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain

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Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial

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Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial

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Molecular Characterization of a Phospholipase D Generating Anandamide and Its Congeners

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Targeting the endocannabinoid system: to enhance or reduce?

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Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors

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Prevention of Alzheimer's Disease Pathology by Cannabinoids: Neuroprotection Mediated by Blockade of Microglial Activation

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An endogenous cannabinoid (2-AG) is neuroprotective after brain injury

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The pharmacokinetics and the pharmacodynamics of cannabinoids

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The endocannabinoid system links gut microbiota to adipogenesis

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Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation

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Nonpsychotropic Cannabinoid Receptors Regulate Microglial Cell Migration

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Alternatively activated microglia and macrophages in the central nervous system

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Cannabinoid CB2Receptors and Fatty Acid Amide Hydrolase Are Selectively Overexpressed in Neuritic Plaque-Associated Glia in Alzheimer's Disease Brains

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Mitochondrial CB1 receptors regulate neuronal energy metabolism

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Endocannabinoid signaling as a synaptic circuit breaker in neurological disease

Katona, I., & Freund, T. F. (2008) · Nature Medicine · doi:10.1038/nm.f.1869 · Cited by 579 · see citing works

Cannabinoids control spasticity and tremor in a multiple sclerosis model

Baker, D., Pryce, G., Croxford, J., Brown, P., Pertwee, R., Huffman, J. W., & Layward, L. (2000) · Nature · doi:10.1038/35003583 · Cited by 546 · see citing works

Commensal bacteria make GPCR ligands that mimic human signalling molecules

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Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain

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Hashish—I

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New approaches and challenges to targeting the endocannabinoid system

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A randomized, double-blind, placebo-controlled, parallel-group, enriched-design study of nabiximols* (Sativex^®), as add-on therapy, in subjects with refractory spasticity caused by multiple sclerosis: Sativex for refractory spasticity in MS

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Hypothalamic POMC neurons promote cannabinoid-induced feeding

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A cannabinoid link between mitochondria and memory

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Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor.

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Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease

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Cannabidiol and Other Cannabinoids Reduce Microglial Activation In Vitro and In Vivo: Relevance to Alzheimer’s Disease

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A Total Synthesis of dl-Δ1-Tetrahydrocannabinol, the Active Constituent of Hashish1

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Brain cannabinoid CB2 receptors modulate cocaine's actions in mice

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The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy

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Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity

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Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation

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Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome

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Endocannabinoids control spasticity in a multiple sclerosis model

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GABA production and structure of gadB / gadC genes in Lactobacillus and Bifidobacterium strains from human microbiota

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Roles of Peroxisome Proliferator-Activated Receptor Gamma on Brain and Peripheral Inflammation

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Endocannabinoids–at the crossroads between the gut microbiota and host metabolism

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Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice

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Effects of cannabidiol in the treatment of patients with Parkinson’s disease: An exploratory double-blind trial

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Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells

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Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity

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Interactions between cannabidiol and commonly used antiepileptic drugs

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Cannabinoids reduce levodopa-induced dyskinesia in Parkinson’s disease: A pilot study

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TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus

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Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo

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N-Oleoyldopamine, a Novel Endogenous Capsaicin-like Lipid That Produces Hyperalgesia

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The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations

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Chemical Basis of Hashish Activity

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Controlled clinical trial of cannabidiol in Huntington's disease

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Experimental Parkinsonism Alters Endocannabinoid Degradation: Implications for Striatal Glutamatergic Transmission

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Pregnenolone Can Protect the Brain from Cannabis Intoxication

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Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties

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Therapeutic Action of Cannabinoids in a Murine Model of Multiple Sclerosis

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Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease

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A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma

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Inhibition of tumor angiogenesis by cannabinoids

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Pharmacology and stereoselectivity of structurally novel cannabinoids in mice.

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Cannabinoid receptor binding and messenger RNA expression in human brain: an in vitro receptor autoradiography and in situ hybridization histochemistry study of normal aged and Alzheimer's brains.

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Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors

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The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic–ischemic brain damage in mice is mediated by CB2 and adenosine receptors

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Gene therapy: can neural stem cells deliver?

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Cannabinoid Type 2 Receptors Mediate a Cell Type-Specific Plasticity in the Hippocampus

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Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial.

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Monoacylglycerol Lipase Is a Therapeutic Target for Alzheimer's Disease

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Monoacylglycerol Lipase Exerts Dual Control over Endocannabinoid and Fatty Acid Pathways to Support Prostate Cancer

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Astroglial CB1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory

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Cannabinoid CB₁and CB₂Receptors and Fatty Acid Amide Hydrolase Are Specific Markers of Plaque Cell Subtypes in Human Multiple Sclerosis

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