Memory's echo: vivid remembering reactivates sensory-specific cortex
Open accessAbstract
A fundamental question in human memory is how the brain represents sensory-specific information during the process of retrieval. One hypothesis is that regions of sensory cortex are reactivated during retrieval of sensory-specific information (1). Here we report findings from a study in which subjects learned a set of picture and sound items and were then given a recall test during which they vividly remembered the items while imaged by using event-related functional MRI. Regions of visual and auditory cortex were activated differentially during retrieval of pictures and sounds, respectively. Furthermore, the regions activated during the recall test comprised a subset of those activated during a separate perception task in which subjects actually viewed pictures and heard sounds. Regions activated during the recall test were found to be represented more in late than in early visual and auditory cortex. Therefore, results indicate that retrieval of vivid visual and auditory information can be associated with a reactivation of some of the same sensory regions that were activated during perception of those items.
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Left planum temporale response is consistent with auditory imagery because it is observed when silently imagining speech or recalling auditory relative to visual associations of a picture.
“The response in the left planum temporale was again consistent with auditory imagery because it was observed when silently imagining speech (Shergill et al., 2001) or for recalling (imagining) the auditory relative to visual associations of a picture of a scene (Wheeler et al., 2000).”
From A review and synthesis of the first 20years of PET and fMRI studies of heard speech, spoken language and reading (2012) · cites this paper as Wheeler et al., 2000
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- Authors
- Wheeler, M. E., Petersen, S. E., & Buckner, R. L.
- Affiliations
- Howard Hughes Medical Institute (US)
- Corresponding author
- Buckner, Randy L.
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 2000-09-26
- Volume
- 97
- Issue
- 20
- Pages
- 11125-11129
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC27159
- OpenAlex
- W2062752228
- Cited by
- 865
- References
- 36
- Citations by year
- 2026: 25 · 2025: 26 · 2024: 35 · 2023: 61 · 2022: 25 · 2021: 41 · 2020: 39 · 2019: 44 · 2018: 27 · 2017: 45 · 2016: 42 · 2015: 34 · 2014: 36 · 2013: 42 · 2012: 38
- FWCI
- 8.83
- Type
- journal article
- Language
- en
- Update notices
- correction (2004-04-06)
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- James S. McDonnell Foundation
- National Institutes of Health (5r01mh057506-05)
- National Institute of Mental Health (MH 57506)
- National Institute of Neurological Disorders and Stroke (NS-32979, R01NS032979)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory Processes and Influences
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
- Keywords
- memory retrieval, visual cortex, auditory cortex, picture recall
- MeSH terms
- Adult, Cerebral Cortex, Female, Humans, Magnetic Resonance Imaging, Male, Memory, Sensory Receptor Cells
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