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From Sirtuin Biology to Human Diseases: An Update

Sebastián, Carlos, Satterstrom, F.Kyle, Haigis, Marcia C., Mostoslavsky, Raul·2012·Journal of Biological Chemistry

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  • Several of the seven mammalian sirtuins can delay various parameters of aging in mice.

    “Regarding mammals, several studies have shown that several of the seven mammalian sirtuins can delay various parameters of aging in mice (Houtkooper et al., 2012; Sebastian et al., 2012).”

    From The Hallmarks of Aging (2013) · cites this paper as Sebastian et al., 2012

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Research works printed but not linked: 80

  1. McCay, 1935, The effect of retarded growth upon the length of life and upon ultimate size, J. Nutr., 10, 63, 10.1093/jn/10.1.63 · DOI · Paper page
  2. Viswanathan, 2011, Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes, Nature, 477, E1, 10.1038/nature10440 · DOI · Paper page
  3. Guarente, 2011, Franklin H. Epstein lecture: sirtuins, aging, and medicine, N. Engl. J. Med., 364, 2235, 10.1056/NEJMra1100831 · DOI · Paper page
  4. Someya, 2010, Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction, Cell, 143, 802, 10.1016/j.cell.2010.10.002 · DOI · Paper page
  5. Liu, 2007, Ageing and hearing loss, J. Pathol., 211, 188, 10.1002/path.2102 · DOI
  6. Mostoslavsky, 2006, Genomic instability and aging-like phenotype in the absence of mammalian SIRT6, Cell, 124, 315, 10.1016/j.cell.2005.11.044 · DOI · Paper page
  7. Lombard, 2012, Ageing: sorting out the sirtuins, Nature, 483, 166, 10.1038/nature10950 · DOI
  8. Cohen, 2004, Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase, Science, 305, 390, 10.1126/science.1099196 · DOI · Paper page
  9. Chakrabarti, 2011, SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL, J. Lipid Res., 52, 1693, 10.1194/jlr.M014647 · DOI
  10. Ponugoti, 2010, SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism, J. Biol. Chem., 285, 33959, 10.1074/jbc.M110.122978 · DOI
  11. Purushotham, 2012, Systemic SIRT1 insufficiency results in disruption of energy homeostasis and steroid hormone metabolism upon high-fat-diet feeding, FASEB J., 26, 656, 10.1096/fj.11-195172 · DOI
  12. Pfluger, 2008, Sirt1 protects against high-fat diet-induced metabolic damage, Proc. Natl. Acad. Sci. U.S.A., 105, 9793, 10.1073/pnas.0802917105 · DOI · Paper page
  13. Qiang, 2011, Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation, Cell Metab., 14, 758, 10.1016/j.cmet.2011.10.007 · DOI · Paper page
  14. Wu, 2011, Overexpression of SIRT1 in mouse forebrain impairs lipid/glucose metabolism and motor function, PLoS ONE, 6, e21759, 10.1371/journal.pone.0021759 · DOI
  15. Hallows, 2011, Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction, Mol. Cell, 41, 139, 10.1016/j.molcel.2011.01.002 · DOI · Paper page
  16. Kim, 2010, Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis, Cell Metab., 12, 224, 10.1016/j.cmet.2010.06.009 · DOI
  17. Jing, 2007, SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation, Cell Metab., 6, 105, 10.1016/j.cmet.2007.07.003 · DOI
  18. Wang, 2009, SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARγ, Mol. Biol. Cell, 20, 801, 10.1091/mbc.e08-06-0647 · DOI
  19. Krishnan, 2012, Dietary obesity-associated Hif1α activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system, Genes Dev., 26, 259, 10.1101/gad.180406.111 · DOI
  20. Nasrin, 2010, SIRT4 regulates fatty acid oxidation and mitochondrial gene expression in liver and muscle cells, J. Biol. Chem., 285, 31995, 10.1074/jbc.M110.124164 · DOI
  21. Zhong, 2010, The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1α, Cell, 140, 280, 10.1016/j.cell.2009.12.041 · DOI · Paper page
  22. Jiang, 2011, Acetylation regulates gluconeogenesis by promoting PEPCK1 degradation via recruiting the UBR5 ubiquitin ligase, Mol. Cell, 43, 33, 10.1016/j.molcel.2011.04.028 · DOI
  23. Shimazu, 2010, SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase 2 and regulates ketone body production, Cell Metab., 12, 654, 10.1016/j.cmet.2010.11.003 · DOI · Paper page
  24. Finley, 2011, Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity, PLoS ONE, 6, e23295, 10.1371/journal.pone.0023295 · DOI
  25. Martinez-Pastor, 2012, Sirtuins, metabolism, and cancer, Front. Pharmacol., 3, 22, 10.3389/fphar.2012.00022 · DOI
  26. Yuan, 2009, A c-Myc-SIRT1 feedback loop regulates cell growth and transformation, J. Cell Biol., 185, 203, 10.1083/jcb.200809167 · DOI
  27. Lim, 2010, Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1α, Mol. Cell, 38, 864, 10.1016/j.molcel.2010.05.023 · DOI · Paper page
  28. Das, 2009, CBP/p300-mediated acetylation of histone H3 on lysine 56, Nature, 459, 113, 10.1038/nature07861 · DOI
  29. Marshall, 2011, SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability, PLoS Genet., 7, e1002135, 10.1371/journal.pgen.1002135 · DOI
  30. Elangovan, 2011, SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer, Cancer Res., 71, 6654, 10.1158/0008-5472.CAN-11-1446 · DOI
  31. Chen, 2011, Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth, Cancer Res., 71, 4138, 10.1158/0008-5472.CAN-10-4274 · DOI
  32. Choi, 2011, Expression and role of SIRT1 in hepatocellular carcinoma, Oncol. Rep., 26, 503
  33. Finley, 2011, SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization, Cancer Cell, 19, 416, 10.1016/j.ccr.2011.02.014 · DOI · Paper page
  34. Van Meter, 2011, SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells, Cell Cycle, 10, 3153, 10.4161/cc.10.18.17435 · DOI
  35. Dryden, 2003, Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle, Mol. Cell. Biol., 23, 3173, 10.1128/MCB.23.9.3173-3185.2003 · DOI
  36. Kim, 2011, SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity, Cancer Cell, 20, 487, 10.1016/j.ccr.2011.09.004 · DOI
  37. Barber, 2012, SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation, Nature, 487, 114, 10.1038/nature11043 · DOI
  38. Gillum, 2011, SirT1 regulates adipose tissue inflammation, Diabetes, 60, 3235, 10.2337/db11-0616 · DOI · Paper page
  39. Schug, 2010, Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress, Mol. Cell. Biol., 30, 4712, 10.1128/MCB.00657-10 · DOI
  40. Yoshizaki, 2010, SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity, Am. J. Physiol. Endocrinol. Metab., 298, E419, 10.1152/ajpendo.00417.2009 · DOI
  41. Wu, 2012, Sirt1 protects against thrombomodulin down-regulation and lung coagulation after particulate matter exposure, Blood, 119, 2422, 10.1182/blood-2011-04-350413 · DOI
  42. Li, 2012, Interferon γ (IFN-γ) disrupts energy expenditure and metabolic homeostasis by suppressing SIRT1 transcription, Nucleic Acids Res., 40, 1609, 10.1093/nar/gkr984 · DOI
  43. Zhang, 2010, Roles of SIRT1 in the acute and restorative phases following induction of inflammation, J. Biol. Chem., 285, 41391, 10.1074/jbc.M110.174482 · DOI · Paper page
  44. Rothgiesser, 2010, SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310, J. Cell Sci., 123, 4251, 10.1242/jcs.073783 · DOI · Paper page
  45. Kawahara, 2011, Dynamic chromatin localization of Sirt6 shapes stress- and aging-related transcriptional networks, PLoS Genet., 7, e1002153, 10.1371/journal.pgen.1002153 · DOI
  46. Kawahara, 2009, SIRT6 links histone H3 lysine 9 deacetylation to NF-κB-dependent gene expression and organismal life span, Cell, 136, 62, 10.1016/j.cell.2008.10.052 · DOI · Paper page
  47. Bruzzone, 2009, Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE, PLoS ONE, 4, e7897, 10.1371/journal.pone.0007897 · DOI
  48. Vakhrusheva, 2008, Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice, Circ. Res., 102, 703, 10.1161/CIRCRESAHA.107.164558 · DOI
  49. Weiss, 2011, Caloric restriction: powerful protection for the aging heart and vasculature, Am. J. Physiol. Heart Circ. Physiol., 301, H1205, 10.1152/ajpheart.00685.2011 · DOI
  50. Haigis, 2010, Mammalian sirtuins: biological insights and disease relevance, Annu. Rev. Pathol., 5, 253, 10.1146/annurev.pathol.4.110807.092250 · DOI · Paper page
  51. Alcendor, 2004, Silent information regulator 2α, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes, Circ. Res., 95, 971, 10.1161/01.RES.0000147557.75257.ff · DOI
  52. Pillai, 2005, Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2α deacetylase activity, J. Biol. Chem., 280, 43121, 10.1074/jbc.M506162200 · DOI
  53. Planavila, 2011, Sirt1 acts in association with PPARα to protect the heart from hypertrophy, metabolic dysregulation, and inflammation, Cardiovasc. Res., 90, 276, 10.1093/cvr/cvq376 · DOI
  54. Leong, 2003, Glycolysis and pyruvate oxidation in cardiac hypertrophy–why so unbalanced?, Comp. Biochem. Physiol. A Mol. Integr. Physiol., 135, 499, 10.1016/S1095-6433(03)00007-2 · DOI
  55. Zhou, 2011, Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction, Circ. Res., 109, 639, 10.1161/CIRCRESAHA.111.243592 · DOI
  56. Cosentino, 2008, Final common molecular pathways of aging and cardiovascular disease: role of the p66Shc protein, Arterioscler. Thromb. Vasc. Biol., 28, 622, 10.1161/ATVBAHA.107.156059 · DOI
  57. Schwer, 2010, Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity, Proc. Natl. Acad. Sci. U.S.A., 107, 21790, 10.1073/pnas.1016306107 · DOI
  58. Kawashima, 2011, Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice, J. Mol. Cell. Cardiol., 51, 1026, 10.1016/j.yjmcc.2011.09.013 · DOI
  59. Sundaresan, 2011, The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy, Sci. Signal., 4, ra46, 10.1126/scisignal.2001465 · DOI
  60. Alcendor, 2007, Sirt1 regulates aging and resistance to oxidative stress in the heart, Circ. Res., 100, 1512, 10.1161/01.RES.0000267723.65696.4a · DOI · Paper page
  61. Sack, 2011, Emerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heart, Am. J. Physiol. Heart Circ. Physiol., 301, H2191, 10.1152/ajpheart.00199.2011 · DOI
  62. Sundaresan, 2009, Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice, J. Clin. Invest., 119, 2758
  63. Pillai, 2010, Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway, J. Biol. Chem., 285, 3133, 10.1074/jbc.M109.077271 · DOI
  64. Lang, 2002, Cardiac hypertrophy and oxidative stress: a leap of faith or stark reality?, Heart, 87, 316, 10.1136/heart.87.4.316 · DOI
  65. Condorelli, 2002, Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice, Proc. Natl. Acad. Sci. U.S.A., 99, 12333, 10.1073/pnas.172376399 · DOI
  66. Yu, 2012, Sirtuin 6 protects cardiomyocytes from hypertrophy in vitro via inhibition of NF-κB-dependent transcriptional activity, Br. J. Pharmacol.
  67. Cai, 2012, Nmnat2 protects cardiomyocytes from hypertrophy via activation of SIRT6, FEBS Lett., 586, 866, 10.1016/j.febslet.2012.02.014 · DOI
  68. Sundaresan, 2012, The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun, Nat. Med., 8, 1643, 10.1038/nm.2961 · DOI
  69. Montecucco, 2012, Inhibition of nicotinamide phosphoribosyltransferase reduces neutrophil-mediated injury in myocardial infarction, Antioxid. Redox Signal.
  70. Donmez, 2010, SIRT1 suppresses β-amyloid production by activating the α-secretase gene ADAM10, Cell, 142, 320, 10.1016/j.cell.2010.06.020 · DOI
  71. Arima, 1998, Immunoelectron-microscopic demonstration of NACP/α-synuclein-epitopes on the filamentous component of Lewy bodies in Parkinson's disease and in dementia with Lewy bodies, Brain Res., 808, 93, 10.1016/S0006-8993(98)00734-3 · DOI
  72. Donmez, 2012, SIRT1 protects against α-synuclein aggregation by activating molecular chaperones, J. Neurosci., 32, 124, 10.1523/JNEUROSCI.3442-11.2012 · DOI
  73. Jiang, 2012, Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets, Nat. Med., 18, 153, 10.1038/nm.2558 · DOI
  74. Jeong, 2012, Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway, Nat. Med., 18, 159, 10.1038/nm.2559 · DOI
  75. Luthi-Carter, 2010, SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis, Proc. Natl. Acad. Sci. U.S.A., 107, 7927, 10.1073/pnas.1002924107 · DOI
  76. Guo, 2011, Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling, J. Neurosci. Res., 89, 1723, 10.1002/jnr.22725 · DOI
  77. Ji, 2011, Sirt2 is a novel in vivo downstream target of Nkx2.2 and enhances oligodendroglial cell differentiation, J. Mol. Cell Biol., 3, 351, 10.1093/jmcb/mjr009 · DOI
  78. Li, 2007, Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating α-tubulin, J. Neurosci., 27, 2606, 10.1523/JNEUROSCI.4181-06.2007 · DOI
  79. Beirowski, 2011, Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling, Proc. Natl. Acad. Sci. U.S.A., 108, E952, 10.1073/pnas.1104969108 · DOI
  80. Kim, 2011, Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture, PLoS ONE, 6, e14731, 10.1371/journal.pone.0014731 · DOI

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Metadata

Authors
Sebastián, C., Satterstrom, F. K., Haigis, M. C., & Mostoslavsky, R.
Venue
Journal of Biological Chemistry
Publisher
Elsevier BV
Published
2012-12
Volume
287
Issue
51
Pages
42444-42452
ISSN
0021-9258
Cited by
201
References
26
Language
en

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