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RTG signaling sustains mitochondrial respiratory capacity in HOG1-dependent osmoadaptation

Guaragnella, N., Agrimi, G., Scarcia, P., Suriano, C., Pisano, I., Bobba, A., Mazzoni, C., Palmieri, L., & Giannattasio, S. (2021) · Microorganisms · doi:10.3390/microorganisms9091894 · Cited by 16 · see citing works

Amyloid protein aggregates: new clients for mitochondrial energy production in the brain?

Sivanesan, S., Chang, E., Howell, M. D., & Rajadas, J. (2020) · FEBS Journal · doi:10.1111/febs.15225 · Cited by 15 · see citing works

Evaluating the Correlations Between Osteoporosis and Lifestyle-Related Factors Using Transcriptome-Wide Association Study

Du, Y., Li, P., Wen, Y., Liang, X., Liu, L., Cheng, B., Ding, M., Zhao, Y., Ma, M., Zhang, L., et al. (2020) · Calcified Tissue International · doi:10.1007/s00223-019-00640-y · Cited by 14 · see citing works

Sirt4 Modulates Oxidative Metabolism and Sensitivity to Rapamycin Through Species-Dependent Phenotypes in Drosophila mtDNA Haplotypes

Sejour, R., Sanguino, R. A., Mikolajczak, M., Ahmadi, W., & Villa-Cuesta, E. (2020) · G3 Genes Genomes Genetics · doi:10.1534/g3.120.401174 · Cited by 14 · see citing works

Nuclear functional role of metabolic enzymes and related metabolites: Focus on gene expression regulation

Todisco, S., Iacobazzi, D., Santarsiero, A., Convertini, P., & Infantino, V. (2025) · Molecular Metabolism · doi:10.1016/j.molmet.2025.102233 · Cited by 15 · see citing works

Specific BK Channel Activator NS11021 Protects Rat Renal Proximal Tubular Cells from Cold Storage—Induced Mitochondrial Injury In Vitro

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Mitochondrial Retrograde Signaling Contributes to Metabolic Differentiation in Yeast Colonies

Plocek, V., Fadrhonc, K., Maršíková, J., Váchová, L., Pokorná, A., Hlaváček, O., Wilkinson, D., & Palková, Z. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115597 · Cited by 10 · see citing works

A quantitative yeast aging proteomics analysis reveals novel aging regulators

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Mitochondrial (dys) function: a double edge sword in cell stress response

Guaragnella, N., Noia, M. A. D., & Primavera, A. (2024) · Frontiers in Cell Death · doi:10.3389/fceld.2024.1467272 · Cited by 9 · see citing works

Vitamin B12 Supplementation Improves Oocyte Development by Modulating Mitochondria and Yolk Protein in a Caffeine-Ingested Caenorhabditis elegans Model

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Cell differentiation, aging, and death in spatially organized yeast communities: mechanisms and consequences

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Protective effect of wheat gluten peptides against ethanol-stress damage in yeast cell and identification of anti-ethanol peptides

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The yeast mitochondrial succinylome: Implications for regulation of mitochondrial nucleoids

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Mitochondria and the reactive species interactome: shaping the future of mitoredox medicine

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Lack of Mitochondrial DNA Provides Metabolic Advantage in Yeast Osmoadaptation

Noia, M. A. D., Ocheja, O. B., Scarcia, P., Pisano, I., Messina, E., Agrimi, G., Palmieri, L., & Guaragnella, N. (2024) · Biomolecules · doi:10.3390/biom14060704 · Cited by 7 · see citing works

Regulation of the mitochondrial permeability transition pore and its effects on aging

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Diversity and Postzygotic Evolution of the Mitochondrial Genome in Hybrids of Saccharomyces Species Isolated by Double Sterility Barrier

Szabó, A. M., Antunovics, Z., Karanyicz, E., & Sipiczki, M. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.00838 · Cited by 7 · see citing works

Cadmium Sulfide Quantum Dots, Mitochondrial Function and Environmental Stress: A Mechanistic Reconstruction through In Vivo Cellular Approaches in Saccharomyces cerevisiae

Marmiroli, M., Birarda, G., Gallo, V., Villani, M., Zappettini, A., Vaccari, L., Marmiroli, N., & Pagano, L. (2023) · Nanomaterials · doi:10.3390/nano13131944 · Cited by 5 · see citing works

Involvement of a G Protein Regulatory Circuit in Alternative Oxidase Production inNeurospora crassa

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Overexpression of a single ORF can extend chronological lifespan in yeast if retrograde signaling and stress response are stimulated

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Co-evolution in the Jungle: From Leafcutter Ant Colonies to Chromosomal Ends

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Compensatory Genetic and Transcriptional Cytonuclear Coordination in Allopolyploid Lager Yeast (Saccharomyces pastorianus)

Zhang, K., Li, J., Guo, L., Zhao, Y., Dong, Y., Zhang, Y., Sun, W., Wang, J., Yao, J., Ma, Y., et al. (2022) · Molecular Biology and Evolution · doi:10.1093/molbev/msac228 · Cited by 4 · see citing works

Developing systems in yeast to address Alzheimer's disease

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Mitochondrial protein import stress augments α-synuclein aggregation and neurodegeneration independent of bioenergeticsPreprint

Coyne, L. P., Rana, A., Wang, X., Bhagwagar, S. Z., Umino, Y., Solessio, E. C., Middleton, F. A., & Chen, X. J. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.09.20.508793 · Cited by 3 · see citing works

Mitochondrial mRNA and the small subunit rRNA in budding yeasts undergo 3′-end processing at conserved species-specific elements

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Transcriptional and epigenetic control of regulated cell death in yeast

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Mitochondria in Cryptococcus: an update of mitochondrial transcriptional regulation in Cryptococcus

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Analysis of Mitochondrial Retrograde Signaling in Yeast Model Systems

Guaragnella, N., Ždralević, M., Palková, Z., & Giannattasio, S. (2021) · Methods in molecular biology · doi:10.1007/978-1-0716-1266-8_6 · Cited by 3 · see citing works

Citrate trafficking supports rewiring of mitochondrial metabolism via RTG signaling in yeast osmoadaptation

Primavera, A., Laera, L., Castegna, A., Scarcia, P., Palmieri, L., Noia, M. A. D., & Guaragnella, N. (2025) · Biochemical Journal · doi:10.1042/bcj20253414 · Cited by 2 · see citing works

Yeast as a Model to Unravel New BRCA2 Functions in Cell Metabolism

Costanza, A., Guaragnella, N., Bobba, A., Manzari, C., L’Abbate, A., Giudice, C. L., Picardi, E., D’Erchia, A. M., Pesole, G., & Giannattasio, S. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.908442 · Cited by 2 · see citing works

Mitochondrial retrograde control of transcription evolves with respiratory stress, metabolic adaptation, and virulence in budding yeasts

Łabędzka-Dmoch, K., Bui, T. H. D., Piątkowski, J., Dilling, M., Jagiełło, P., Kabza, W., & Golik, P. (2026) · Molecular Biology and Evolution · doi:10.1093/molbev/msag005 · Cited by 1 · see citing works

Synthetic lethality between toxic amino acids, RTG‐target genes and chaperones in Saccharomyces cerevisiae

Druseikis, M. E., & Covo, S. (2024) · Yeast · doi:10.1002/yea.3975 · Cited by 1 · see citing works

Oxidative Stress-Tolerating Yeasts

Zadrąg‐Tęcza, R., Maślanka, R., & Kwolek‐Mirek, M. (2025) · Springer eBooks · doi:10.1007/978-3-031-97453-3_9 · Cited by 1 · see citing works

Mitochondrial dysfunction redirects proton transport and energy homeostasis in Saccharomyces cerevisiae under variable pH and glucose conditions

Anikyan, L., Shirvanyan, A. H., Guaragnella, N., & Trchounian, K. A. (2026) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2026.149595 · Cited by 1 · see citing works

Mitochondrial proteostasis, unfolded protein response, and its relation to cancer

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Mitochondrial Metabolic Programming and Crosstalk to Nucleus

do Amaral, M. A., Padovani, B. N., Paredes, L. C., Mendonça-Gomes, J. M., Pereira, M. T., & Câmara, N. O. S. (2023) · Current Tissue Microenvironment Reports · doi:10.1007/s43152-023-00048-9 · Cited by 1 · see citing works

Epigenome-wide association study of nuclear DNA methylation in relation to mitochondrial heteroplasmy

Lai, M. M., Kim, K., Zheng, Y., Castellani, C. A., Ratliff, S. M., Wang, M., Liu, X., Haessler, J., Huan, T., Bonsu, K., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-65845-2 · Cited by 1 · see citing works

Flux Regulation Through Glycolysis and Respiration is Balanced by Inositol PyrophosphatesPreprint

Qin, N., Li, L., Ji, X., Pereira, R., Chen, Y., Yin, S., Li, C., Wan, X., Luo, H., Zhang, Y., et al. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4135724 · Cited by 1 · see citing works

The Reactive Species Interactome - Mitochondria AxisPreprint

Châtre, L. (2022) · Preprints.org · doi:10.20944/preprints202205.0289.v1

Carnitine metabolism in relation to physical performance and cognition in aging

van der Hoek, M. D. (2020) · doi:10.18174/513041

Checks and balances of the RTG pathway under arginine deprivation and canavanine exposure in Saccharomyces cerevisiaePreprint

Druseikis, M. E., & Covo, S. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.02.21.481281

Mitochondrial Research: Yeast and Human Cells as Models

Ždralević, M., & Giannattasio, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23126654

Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathwayPreprint

Zhang, J., Simpson, C. M., Berner, J., Chong, H. B., Fang, J., Ordulu, Z., Weiss‐Sadan, T., Possemato, A. P., Harry, S. A., Takahashi, M., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.03.11.532189

Epigenome-wide Association Analysis of Mitochondrial Heteroplasmy Provides Insight into Molecular Mechanisms of DiseasePreprint

Lai, M. M., Kim, K., Zheng, Y., Castellani, C. A., Ratliff, S. M., Wang, M., Liu, X., Haessler, J., Huan, T., Bielak, L. F., et al. (2024) · medRxiv · doi:10.1101/2024.12.05.24318557

Mitochondrial Double-Stranded RNA Triggers Ferroptosis via PKR–ISR Signaling in Renal Ischemia–Reperfusion InjuryPreprint

Justin, R., Criste, M. S., Park, S., Kusuma, F., Lee, N., Yang, Y., Nguyen, K. A., Park, S., 김정안, Gil, H., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.19.700463

Enhanced Untargeted Metabolomics Based on High-Resolution Mass Spectrometry Reveals Global Rewiring Due to Mitochondrial Dysfunction in Yeast

Mastrorocco, F., Martino, L. D., Fochi, I., Pesole, G., Picardi, E., Musicco, C., & Giannattasio, S. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27062624

Yeast models of diseases linked to the mitochondrial ATP6 gene : molecular bases and therapeutic prospects

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The role of GATOR1 complex, upstream regulator of mTORC1 pathway, in mitochondrial function

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Development and Differentiation of Yeast Colonies and Biofilms

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HSP27, cell stress, and hormesis: From mammals to humanized yeast models

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Communication Between Mitochondria and the Nucleus in Regulation of Cytochrome Genes in the Yeast Saccharomyces cerevisiae

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Decoding the Rosetta stone of mitonuclear communication

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Yeast as a Tool to Study Signaling Pathways in Mitochondrial Stress Response and Cytoprotection

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Power2: The power of yeast genetics applied to the powerhouse of the cell

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