Mitonuclear communication in homeostasis and stress

The Hallmarks of Aging

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ROS function in redox signaling and oxidative stress

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A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

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Mitochondrial DNA stress primes the antiviral innate immune response

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Mitochondrial form and function

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Mitochondria as sensors and regulators of calcium signalling

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Tlr signalling augments macrophage bactericidal activity through mitochondrial ros

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Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

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Heat shock factors: integrators of cell stress, development and lifespan

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Ca2+/calmodulin-dependent protein kinase kinase-β acts upstream of AMP-activated protein kinase in mammalian cells

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Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

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Mitochondrial ROS Signaling in Organismal Homeostasis

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Telomere dysfunction induces metabolic and mitochondrial compromise

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Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

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Regulation of Yeast Replicative Life Span by TOR and Sch9 in Response to Nutrients

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The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

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Regulation of pgc-1α, a nodal regulator of mitochondrial biogenesis

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The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

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Rates of Behavior and Aging Specified by Mitochondrial Function During Development

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Peroxisome Proliferator-Activated Receptor γ Coactivator 1 Coactivators, Energy Homeostasis, and Metabolism

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The Cell Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity

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Mitonuclear protein imbalance as a conserved longevity mechanism

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Mitochondrial Import Efficiency of ATFS-1 Regulates Mitochondrial UPR Activation

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A mitochondrial specific stress response in mammalian cells

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TRB3, a novel ER stress‐inducible gene, is induced via ATF4–CHOP pathway and is involved in cell death

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International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors

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Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

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The Human Mitochondrial Transcriptome

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A new pathway for mitochondrial quality control: Mitochondrial-derived vesicles

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The eIF2α kinases: their structures and functions

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PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activation

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Activation of peroxisome proliferator-activated receptor δ induces fatty acid β-oxidation in skeletal muscle and attenuates metabolic syndrome

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Activation of the human mitochondrial transcriptionfactor A gene by nuclear respiratory factors: a potential regulatory linkbetween nuclear and mitochondrial gene expression in organellebiogenesis.

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Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

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Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

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On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1Preprint

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The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance

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Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) and PGC-1 family coactivators

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Regulation of mitochondrial biogenesis in skeletal muscle by CaMK

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Mitochondrial retrograde signaling

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Mitochondrial Electron Transport Is a Key Determinant of Life Span in Caenorhabditis elegans

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The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in <i>C. elegans</i>

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A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans

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Mitohormesis

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A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

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ClpP Mediates Activation of a Mitochondrial Unfolded Protein Response in C. elegans

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The ubiquitin ligase parkin mediates resistance to intracellular pathogens

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The metabolite alpha-ketoglutarate extends lifespan by inhibiting the ATP synthase and TOR

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Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway

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New roles for mitochondrial proteases in health, ageing and disease

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Inhibition of Respiration Extends C. elegans Life Span via Reactive Oxygen Species that Increase HIF-1 Activity

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A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

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Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts

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Tetracyclines disturb mitochondrial function across eukaryotic models: a call for caution in biomedical research

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The matrix peptide exporter HAF-1 signals a mitochondrial unfolded protein response by activating the transcription factor ZC376.7 in C. elegans

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Mitochondrial and Nuclear Accumulation of the Transcription Factor ATFS-1 Promotes OXPHOS Recovery during the UPRmt

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Mistargeted mitochondrial proteins activate a proteostatic response in the cytosol

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The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress responsePreprint

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Phosphorylation of eIF2 Facilitates Ribosomal Bypass of an Inhibitory Upstream ORF to Enhance CHOP Translation

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Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal

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FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study

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Genome-wide Orchestration of Cardiac Functions by the Orphan Nuclear Receptors ERRα and γ

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Unraveling the Truth About Antioxidants: Mitohormesis explains ROS-induced health benefits

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Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing

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The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria

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Extension of Drosophila Life Span by RNAi of the Mitochondrial Respiratory Chain

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Muscle Mitohormesis Promotes Longevity via Systemic Repression of Insulin Signaling

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Induction of Cytoprotective Genes Through Nrf2 / Antioxidant Response Element Pathway: A New Therapeutic Approach for the Treatment of Inflammatory Diseases

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Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

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Pharmacological approaches to restore mitochondrial function

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Ubiquitin-Like Protein 5 Positively Regulates Chaperone Gene Expression in the Mitochondrial Unfolded Protein Response

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Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

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Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk

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Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

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A cytosolic network suppressing mitochondria-mediated proteostatic stress and cell death

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Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint

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Mild mitochondrial uncoupling in mice affects energy metabolism, redox balance and longevity

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Evolutionary conservation of the <i>clk-1</i> -dependent mechanism of longevity: loss of <i>mclk1</i> increases cellular fitness and lifespan in mice

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The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease

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Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae

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