Cited by 152Ethics and Social Impacts of AIArtificial Intelligence in Healthcare and EducationExplainable Artificial Intelligence (XAI)

The DOI matches its Crossref record; 166 of the 166 references it cites were found in a registry or an index; 5 of the 141 sources its claims cite were checked for support.

Ethical Framework for Harnessing the Power of AI in Healthcare and Beyond

Open access

Abstract

In the past decade, the deployment of deep learning (Artificial Intelligence (AI)) methods has become pervasive across a spectrum of real-world applications, often in safety-critical contexts. This comprehensive research article rigorously investigates the ethical dimensions intricately linked to the rapid evolution of AI technologies, with a particular focus on the healthcare domain. Delving deeply, it explores a multitude of facets including transparency, adept data management, human oversight, educational imperatives, and international collaboration within the realm of AI advancement. Central to this article is the proposition of a conscientious AI framework, meticulously crafted to accentuate values of transparency, equity, answerability, and a human-centric orientation. The second contribution of the article is the in-depth and thorough discussion of the limitations inherent to AI systems. It astutely identifies potential biases and the intricate challenges of navigating multifaceted contexts. Lastly, the article unequivocally accentuates the pressing need for globally standardized AI ethics principles and frameworks. Simultaneously, it aptly illustrates the adaptability of the ethical framework proposed herein, positioned skillfully to surmount emergent challenges.

Overview

AI snapshot

Written from the paper’s full text.

TL;DR

This article reviews ethical dimensions of AI in healthcare and beyond, arguing for transparency, equity, accountability, and human-centric design, and proposes a six-pillar ethical framework plus governance/collaboration components. It catalogs AI limitations such as black-box opacity, bias, limited contextual and emotional intelligence, and trust/accountability challenges, while calling for globally standardized AI ethics principles.

Key findings

  • Proposes a conscientious AI framework emphasizing transparency, equity, answerability, and human-centric orientation, with six pillars: Sensitivity, Evaluation, User-Centricity, Responsibility, Beneficence, and Security.
  • Identifies major AI limitations: black-box/explainability problems, bias and fairness concerns (statistical, social, systematic, generalization, and human bias), limited contextual intelligence, erosion of human connection/empathy, and challenges to trust, reliability, and accountability.
  • Cites illustrative evidence: an algorithm using healthcare spending would reduce the number of Black patients identified as needing extra care by over 50%; a 2018 London Metropolitan Police facial recognition system identified 104 previously unknown suspects but only 2 were accurately predicted; GPT-4 as a medicine chatbot offers benefits but risks misinformation, overreliance, ethical/legal concerns, and lack of emotional support.
  • Calls for globally standardized AI ethics principles and frameworks, and outlines a governance/collaboration ecosystem including Human Oversight and Intervention (HOI), Multi-Stakeholder Engagement (MSE), Privacy by Design (PbD), Safe AI, Ethical Governance Council (EGC), Awareness Programs, Continuous Improvement and Adaptability (CIA), and Inter-Generational Considerations (IGC).

Methods

  • Design: comprehensive research article and conceptual review/framework proposal, not an empirical study.
  • Data or sample: no primary dataset or sample is reported; the paper draws on literature, examples, and legal frameworks such as GDPR and HIPAA.
  • Main analysis: thematic discussion of ethical dimensions, AI limitations, data privacy/consent, and the proposed six-pillar ethical framework and governance/collaboration ecosystem.

Limitations

  • The paper states limitations inherent to AI systems—bias, black-box opacity, contextual intelligence, lack of empathy, and trust/accountability challenges—but does not state limitations of its own framework.
  • Evident from the text: the proposed framework is conceptual and not empirically validated; no systematic review protocol, sample, or quantitative evaluation is reported.
  • Evident from the text: examples are illustrative and drawn from secondary sources, with no primary data collection or validation of the proposed pillars.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.1109/access.2024.3369912

Cites

166 of 166 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Verification

Claims the paper makes

120 Not checked yet · 21 Own interpretation · 11 No basis given · 3 Partly supported · 1 Couldn’t confirm · accuracy not yet measured

Verify all 136 references — free account

Show all 88 claims

  • It may state two separate claims as one. 36
  • Probably not a substantial claim. 43
68 of 68
  • The paper relies on this without support.

    The deployment of deep learning AI methods has become pervasive across a spectrum of real-world applications, often in safety-critical contexts.

    “In the past decade, the deployment of deep learning (Artificial Intelligence (AI)) methods has become pervasive across a spectrum of real-world applications, often in safety-critical contexts.”
  • The paper relies on this without support.

    In healthcare, decisions can have life-and-death consequences.

    “In healthcare, where decisions can have life-and-death consequences, it is crucial to have a clear understanding of how AI algorithms arrive at their recommendations.”
  • The paper relies on this without support.

    Evidence-based medicine has long been the gold standard for treatment strategies.

    “Evidence-based medicine has long been the gold standard for treatment strategies.”
  • The paper relies on this without support.

    The size and complexity of models, particularly deep neural networks, have increased in pursuit of better predictive performance.

    “The size and complexity of models, particularly deep neural networks (DNNs), have increased in pursuit of better predictive performance.”
  • The paper relies on this without support.

    Limited generalization of AI models is a critical challenge in deploying AI systems in healthcare.

    “One of the critical challenges in deploying AI systems in healthcare is the limited generalization of models and ensuring their safety.”
  • The paper relies on this without support.

    AI models may have limited exposure to rare medical conditions or unique patient cases during training, compromising their ability to accurately diagnose or treat such cases.

    “Moreover, AI models may have limited exposure to rare medical conditions or unique patient cases during training.Consequently, their ability to accurately diagnose or treat such cases may be compromised.”
  • The paper relies on this without support.

    The lack of diversity within AI development teams may result in models that fail to adequately address the diverse needs of the users.

    “Moreover, the lack of diversity within AI development teams may result in models that fail to adequately address the diverse needs of the users.”
  • The paper relies on this without support.

    Cost and affordability pose barriers, hindering access to AI advancements for those with limited financial resources.

    “Additionally, cost and affordability pose barriers, hindering access to AI advancements for those with limited financial resources.”
  • The paper relies on this without support.

    Cultural and language barriers can restrict the inclusivity and effectiveness of AI systems.

    “Cultural and language barriers can also restrict the inclusivity and effectiveness of AI systems.”
  • The paper relies on this without support.

    AI's limited learning from user interactions and difficulty in handling uncertainty and ambiguity pose obstacles to human-AI interaction.

    “AI's limited learning from user interactions and difficulty in handling uncertainty and ambiguity also pose obstacles.”
  • The paper relies on this without support.

    Users may develop over-reliance on AI, leading to frustration and reduced trust when AI fails to meet their expectations.

    “Users may develop over-reliance on AI, leading to frustration and reduced trust when AI fails to meet their expectations.”
  • The paper relies on this without support.

    Implementing transparent and XAI models fosters trust and accountability.

    “Implementing transparent and XAI models fosters trust and accountability.”
  • The paper relies on this without support.

    The effectiveness of privacy protection laws in practice varies.

    “However, the effectiveness of these laws in practice varies.”
  • The paper relies on this without support.

    Automated decision-making, profiling, and the utilization of ML techniques are reshaping data processing, yet they bring forth concerns of bias and privacy invasion.

    “Automated decision-making, profiling, and the utilization of ML techniques are reshaping data processing, yet they bring forth concerns of bias and privacy invasion.”
  • The paper relies on this without support.

    AI algorithms often process vast amounts of health data to generate insights and recommendations.

    “AI algorithms often process vast amounts of health data to generate insights and recommendations.”
  • The paper relies on this without support.

    AI has the potential to perpetuate biases and stereotypes.

    “With AI's potential to perpetuate biases, this pillar advocates systems to perpetuate biases and stereotypes, this pillar supports continuous monitoring and mitigation of biases through data curation, algorithm design, and stakeholder diversity.”
  • The paper relies on this without support.

    AI models can be vulnerable in unique ways beyond traditional cybersecurity.

    “This goes beyond traditional cybersecurity, the AI models can be vulnerable in unique ways.”
  • The paper relies on this without support.

    Privacy concerns emerge due to the sensitive nature of data processed by AI systems.

    “Privacy concerns emerge due to the sensitive nature of data processed by AI systems.”
  • The paper relies on this without support.

    Economic incentives that drive AI development can profoundly influence its direction.

    “Though it is not necessarily an ethical consideration, the economic incentives that drive AI development can profoundly influence its direction.”
  • The paper relies on this without support.

    AI continues to grapple with comprehending the nuances and intricacies of human context.

    “While AI has made remarkable strides, it continues to grapple with comprehending the nuances and intricacies of human context.”
  • The paper relies on this without support.

    Understanding complex language and emotional nuances remains challenging as AI and humans interact.

    “Additionally, as AI and humans interact, understanding complex language and emotional nuances remains challenging.”
  • The paper relies on this without support.

    Educated decisions can only be made when individuals understand the implications and consequences of AI applications.

    “Educated decisions can only be made when individuals understand the implications and consequences of AI applications.”
22 of 22

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2 of 2

Citations

Cites

Research works printed but not linked: 7

  1. Santow, 2020, Can artificial intelligence be trusted with our human rights?, AQ, Austral. Quart., 91, 10
  2. Božić, 2023, Artifical intelligence as the reason and the solution of digital divide, Lang. Educ. Technol., 3, 90
  3. West, 2019, Discriminating systems, AI Now, 1
  4. Beck, 2017, The rise of AI makes emotional intelligence more important, Harvard Bus. Rev., 15
  5. 2016, Regulation EU 2016/679 of the European Parliament and of the Council of 27 April 2016 on the Protection of Natural Persons With Regard to the Processing of Personal Data and on the Free Movement of Such Data, and Repealing Directive 95/46/EC (General Data Protection Regulation)
  6. 2016, Guidelines on Consent Under Regulation 2016/679 (WP259REV. 01)
  7. 2022, US Department of Health & Human Services

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Metadata

Authors
Nasir, S., Khan, R. A., & Bai, S.
Affiliations
Salim Habib University (PK)
Venue
IEEE Access
Published
2024
Volume
12
Pages
31014-31035
ISSN
2169-3536 (ISSN-L)
OpenAlex
W4392172846
Cited by
152
References
158
Citations by year
2026: 64 · 2025: 60 · 2024: 28
FWCI
62.79
Type
journal article
Language
en
Open access
Locations
  • IEEE Access (publishedVersion, cc-by-nc-nd)
  • arXiv (Cornell University) (submittedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • arXiv (Cornell University) (cc-by)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Ethics and Social Impacts of AI
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Physical Sciences › Computer Science › Artificial Intelligence › Explainable Artificial Intelligence (XAI)
Keywords
AI ethics, ethical frameworks, artificial intelligence in healthcare, deep learning, transparency, data management, human oversight, artificial intelligence in education, international cooperation, algorithmic bias, equity, accountability, safety-critical systems

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