Microbiome in healthy skin, update for dermatologists
Open accessAbstract
The skin is a complex barrier organ made of a symbiotic relationship between microbial communities and host tissue via complex signals provided by the innate and the adaptive immune systems. It is constantly exposed to various endogenous and exogenous factors which impact this balanced system potentially leading to inflammatory skin conditions comprising infections, allergies or autoimmune diseases. Unlike the gut and stool microbiome which has been studied and described for many years, investigations on the skin or scalp microbiome only started recently. Researchers in microbiology and dermatology started using modern methods such as pyrosequencing assays of bacterial 16S rRNA genes to identify and characterize the different microorganisms present on the skin, to evaluate the bacterial diversity and their relative abundance and to understand how microbial diversity may contribute to skin health and dermatological conditions. This article aims to provide an overview on the knowledge about the skin microbiota, the microbiome and their importance in dermatology.
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The equilibrium of human skin microbiota plays a key role in skin health.
“The equilibrium of human skin microbiota plays a key role in skin health (see our previous review70).”
From The impact of airborne pollution on skin (2019) · cites this paper as [70]
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Lacour, J. (2015) · Annales de dermatologie et de vénéréologie · doi:10.1016/s0151-9638(15)30003-x · Cited by 10 · see citing works
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Flagged first, then by citations
Cited by
Sorted by citations
The impact of airborne pollution on skin
Araviiskaia, E., Berardesca, E., Bieber, T., Gontijo, G., Sanchez Viera, M., Marrot, L., Chuberre, B., & Dreno, B. (2019) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.15583 · Cited by 214 · see citing works
Self-citationLi, H., Li, B., Lv, D., Li, W., Lu, Y., & Luo, G. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.114778 · Cited by 142 · see citing works
Oral microbiome alterations of healthy volunteers with proton pump inhibitor
Mishiro, T., Oka, K., Kuroki, Y., Takahashi, M., Tatsumi, K., Saitoh, T., Tobita, H., Ishimura, N., Sato, S., Ishihara, S., et al. (2018) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14040 · Cited by 96 · see citing works
Lunjani, N., Hlela, C., & O’Mahony, L. (2019) · Current Opinion in Allergy & Clinical Immunology · doi:10.1097/aci.0000000000000542 · Cited by 93 · see citing works
Climate change, the cutaneous microbiome and skin disease: Implications for a warming world
Isler, M. F., Coates, S. J., & Boos, M. D. (2023) · International Journal of Dermatology · doi:10.1111/ijd.16297 · Cited by 70 · see citing works
Non-Melanoma Skin Cancer: news from microbiota research
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Kim, K., Jang, H., Kim, E., Kim, H., & Sung, G. Y. (2023) · Experimental Dermatology · doi:10.1111/exd.14940 · Cited by 24 · see citing works
- Authors
- Dréno, B., Araviiskaia, E., Berardesca, E., Gontijo, G., Sanchez Viera, M., Xiang, L. F., Martin, R., & Bieber, T.
- Affiliations
- Université de Nantes (FR)
- First Pavlov State Medical University of St. Petersburg (RU)
- San Gallicano Hospital (IT)
- Universidade Federal de Minas Gerais (BR)
- Institute for Dermatology, Skin Health, Aging and Cancer Madrid Spain
- Shanghai Medical College of Fudan University (CN)
- L'Oréal (France) (FR)
- University Hospital Bonn (DE)
- Corresponding author
- Dréno, B.
- Venue
- Journal of the European Academy of Dermatology and Venereology
- Publisher
- Wiley
- Published
- 2016-10-13
- Volume
- 30
- Issue
- 12
- Pages
- 2038-2047
- ISSN
- 0926-9959 (ISSN-L)
- 1468-3083
- PMC
- PMC6084363
- OpenAlex
- W2531188557
- Cited by
- 292
- References
- 105
- Citations by year
- 2026: 18 · 2025: 36 · 2024: 45 · 2023: 34 · 2022: 36 · 2021: 48 · 2020: 28 · 2019: 17 · 2018: 16 · 2017: 12 · 2016: 2
- FWCI
- 2.25
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of the European Academy of Dermatology and Venereology (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Funders
- Active Cosmetics International, Asnières sur Seine, France
- Topics
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Dermatology › Contact Dermatitis and Allergies
- Keywords
- skin microbiome, healthy skin, host-microbe symbiosis, skin barrier, bacterial diversity, 16S rRNA gene sequencing, inflammatory skin diseases, autoimmune skin disease, allergic skin diseases, skin infections, scalp microbiome
- MeSH terms
- Dermatologists, Bacteria, Humans, RNA, Ribosomal, 16S, Skin, Microbiota
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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