Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 247

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

The Mechanics of Traumatic Brain Injury: A Review of What We Know and What We Need to Know for Reducing Its Societal Burden

Open access
Meaney, David F., Morrison, Barclay, Dale Bass, Cameron·2014·Journal of Biomechanical Engineering
DOI 10.1115/1.4026364
Open this paper in CoChat — free account

Abstract

Traumatic brain injury (TBI) is a significant public health problem, on pace to become the third leading cause of death worldwide by 2020. Moreover, emerging evidence linking repeated mild traumatic brain injury to long-term neurodegenerative disorders points out that TBI can be both an acute disorder and a chronic disease. We are at an important transition point in our understanding of TBI, as past work has generated significant advances in better protecting us against some forms of moderate and severe TBI. However, we still lack a clear understanding of how to study milder forms of injury, such as concussion, or new forms of TBI that can occur from primary blast loading. In this review, we highlight the major advances made in understanding the biomechanical basis of TBI. We point out opportunities to generate significant new advances in our understanding of TBI biomechanics, especially as it appears across the molecular, cellular, and whole organ scale.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1115/1.4026364

Cites

10 of 10 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 10 references

Research works printed but not linked: 228

  1. Faul, M., Xu, L., and Coronado, V. G., 2010, Traumatic Brain Injury in the United States: Emergency Department Visits, Hospitalizations, and Deaths, CDC, Atlanta, GA. · DOI · Paper page
  2. 2011, Epidemiology of Concussion and Mild Traumatic Brain Injury, PM R, 3, S354
  3. 2011, Surveillance for Traumatic Brain Injury-related Deaths—United States, 1997–2007, MMWR Surveill. Summ., 60, 1
  4. 2013, CDC Grand Rounds: Reducing Severe Traumatic Brain Injury in the United States, MMWR Morb. Mortal. Wkly. Rep., 62, 549
  5. 2001, The State of Head Injury Biomechanics: Past, Present, and Future: Part 1, Crit. Rev. Biomed. Eng., 29, 441
  6. 2011, Biomechanics of Concussion, Clin. Sports Med., 30, 19, 10.1016/j.csm.2010.08.009 · DOI · Paper page
  7. 2012, Quantitative Imaging Methods for the Development and Validation of Brain Biomechanics Models, Annu. Rev. Biomed. Eng., 14, 369, 10.1146/annurev-bioeng-071811-150032 · DOI
  8. 2007, CNS Injury Biomechanics and Experimental Models, Prog. Brain Res., 161, 13, 10.1016/S0079-6123(06)61002-9 · DOI · Paper page
  9. 2000, Fundamentals of Impact Biomechanics: Part I–Biomechanics of the Head, Neck, and Thorax, Annu. Rev. Biomed. Eng., 2, 55, 10.1146/annurev.bioeng.2.1.55 · DOI
  10. 2008, Blast Related Neurotrauma: A Review of Cellular Injury, Mol. Cell Biomech., 5, 155
  11. 1982, Influence of the Type of Intracranial Lesion on Outcome From Severe Head Injury, J. Neurosurg., 56, 26, 10.3171/jns.1982.56.1.0026 · DOI · Paper page
  12. 2012, Epidemiology of Moderate-to-Severe Penetrating Versus Closed Traumatic Brain Injury in the Iraq and Afghanistan Wars, J. Trauma Acute Care Surg., 73, S496
  13. 2011, Epidemiology, Severity Classification, and Outcome of Moderate and Severe Traumatic Brain Injury: A Prospective Multicenter Study, J. Neurotrauma, 28, 2019, 10.1089/neu.2011.2034 · DOI · Paper page
  14. 2000, Dynamic Mechanical Stretch of Organotypic Brain Slice Cultures Induces Differential Genomic Expression: Relationship to Mechanical Parameters, ASME J. Biomech. Eng., 122, 224, 10.1115/1.429650 · DOI
  15. 2000, Traumatic Brain Injury Alters the Molecular Fingerprint of TUNEL-Positive Cortical Neurons in vivo: A Single-Cell Analysis, J. Neurosci., 20, 4821, 10.1523/JNEUROSCI.20-13-04821.2000 · DOI
  16. 2004, Methodological Considerations Regarding Single-Cell Gene Expression Profiling for Brain Injury, Neurochem. Res., 29, 1113, 10.1023/B:NERE.0000023598.04937.83 · DOI
  17. 2011, Survival Risk Assessment for Primary Blast Exposures to the Head, J. Neurotrauma, 28, 2319, 10.1089/neu.2009.1207 · DOI
  18. 2012, Brain Injuries From Blast, Ann. Biomed. Eng., 40, 185, 10.1007/s10439-011-0424-0 · DOI · Paper page
  19. 2012, A Multiscale Approach to Blast Neurotrauma Modeling: Part II: Methodology for Inducing Blast Injury to in vitro Models, Front Neurol., 3, 1–10
  20. 1995, Trends in Death Associated With Traumatic Brain Injury, 1979 Through 1992. Success and Failure, JAMA, 273, 1778, 10.1001/jama.1995.03520460060036 · doi:10.1001/jama.1995.03520460060036 · Paper page
  21. 2002, Surveillance for Traumatic Brain Injury Deaths—United States, 1989–1998, MMWR Surveill. Summ., 51, 1
  22. 2010, The Changing Face of Mild Head Injury: Temporal Trends and Patterns in Adolescents and Adults From 1997 to 2008, Injury, 41, 913, 10.1016/j.injury.2010.03.002 · doi:10.1016/j.injury.2010.03.002
  23. 2005, War Neurotrauma: the Defense and Veterans Brain Injury Center (DVBIC) Experience at Walter Reed Army Medical Center (WRAMC), J. Neurotrauma, 22, 1178
  24. 2005, Traumatic Brain Injury in the War Zone, N. Engl. J. Med., 352, 2043, 10.1056/NEJMp058102 · DOI · Paper page
  25. 2010, Mild Traumatic Brain Injury (Concussion) During Combat: Lack of Association of Blast Mechanism With Persistent Postconcussive Symptoms, J. Head Trauma Rehabil., 25, 9, 10.1097/HTR.0b013e3181bd090f · DOI · Paper page
  26. 2010, Traumatic Brain Injury Hospitalizations of U.S. Army Soldiers Deployed to Afghanistan and Iraq, Am. J. Prev. Med., 38, S108
  27. 2008, Combat Wounds in Operation Iraqi Freedom and Operation Enduring Freedom, J. Trauma, 64, 295, 10.1097/TA.0b013e318163b875 · DOI · Paper page
  28. 2012, Brain Injury Risk From Primary Blast, J. Trauma Acute Care Surg., 73, 895, 10.1097/TA.0b013e31825a760e · DOI
  29. 1971, The Biodynamics of Airblast
  30. 1993, Mechanisms of Brain Injury, J. Emerg. Med., 11, 5
  31. 2006, Wartime Traumatic Cerebral Vasospasm: Recent Review of Combat Casualties, Neurosurgery, 59, 1215, 10.1227/01.NEU.0000249190.46033.94 · DOI · Paper page
  32. 2009, Explosive Blast Neurotrauma, J. Neurotrauma, 26, 815, 10.1089/neu.2007.0484 · DOI · Paper page
  33. 1982, Diffuse Axonal Injury and Traumatic Coma in the Primate, Ann. Neurol., 12, 564, 10.1002/ana.410120611 · DOI · Paper page
  34. 2007, Cellular and Subcellular Change Evoked by Diffuse Traumatic Brain Injury: a Complex Web of Change Extending Far Beyond Focal Damage, Prog. Brain Res., 161, 43, 10.1016/S0079-6123(06)61004-2 · DOI · Paper page
  35. 2013, Electrophysiological White Matter Dysfunction and Association With Neurobehavioral Deficits Following Low-Level Primary Blast Trauma, Neurobiol. Dis., 52, 150, 10.1016/j.nbd.2012.12.002 · DOI
  36. 2011, Blast Exposure in Rats With Body Shielding Is Characterized Primarily by Diffuse Axonal Injury, J. Neurotrauma, 28, 947, 10.1089/neu.2010.1540 · DOI · Paper page
  37. 1999, Diffuse Axonal Pathology Detected With Magnetization Transfer Imaging Following Brain Injury in the Pig, Magn. Reson. Med., 41, 727, 10.1002/(SICI)1522-2594(199904)41:4<727::AID-MRM11>3.0.CO;2-6 · DOI
  38. 1996, Magnetization Transfer Imaging of Diffuse Axonal Injury Following Experimental Brain Injury in the Pig: Characterization by Magnetization Transfer Ratio With Histopathologic Correlation, J. Comput. Assist. Tomogr., 20, 540, 10.1097/00004728-199607000-00007 · DOI
  39. 1982, Diffuse Axonal Injury due to Nonmissile Head Injury in Humans: An Analysis of 45 Cases, Ann. Neurol., 12, 557, 10.1002/ana.410120610 · DOI · Paper page
  40. 2009, Association of Contact Loading in Diffuse Axonal Injuries From Motor Vehicle Crashes, J. Trauma, 66, 309, 10.1097/TA.0b013e3181692104 · DOI
  41. 2010, Prevalence and Impact of Diffuse Axonal Injury in Patients With Moderate and Severe Head Injury: A Cohort Study of Early Magnetic Resonance Imaging Findings and 1-Year Outcome, J. Neurosurg., 113, 556, 10.3171/2009.9.JNS09626 · DOI · Paper page
  42. 2012, Review: Managing Posttraumatic Stress Disorder in Combat Veterans With Comorbid Traumatic Brain Injury, J. Rehabil. Res. Dev., 49, 789, 10.1682/JRRD.2011.10.0185 · DOI
  43. 2012, Brain Tissue Volumes in the General Population of the Elderly: The AGES-Reykjavik Study, Neuroimage, 59, 3862, 10.1016/j.neuroimage.2011.11.024 · DOI
  44. 2011, Default Mode Network Functional and Structural Connectivity After Traumatic Brain Injury, Brain, 134, 2233, 10.1093/brain/awr175 · DOI · Paper page
  45. 1994, Physical Properties of Brain Tissue, 70
  46. 1976, Handbook of Human Tolerance
  47. 2008, Mechanical Properties of Dura Mater From the Rat Brain and Spinal Cord, J. Neurotrauma, 25, 38, 10.1089/neu.2007.0348 · DOI · Paper page
  48. 1996, Mechanical Properties of the Human Lumbar Dura Mater, Arq. Neuropsiquiatr, 54, 455, 10.1590/S0004-282X1996000300015 · DOI
  49. 1983, Viscoelastic Behavior of Human Connective Tissues: Relative Contribution of Viscous and Elastic Components, Connect Tissue Res., 12, 59, 10.3109/03008208309005612 · DOI · Paper page
  50. 1981, The Mechanical Properties of Human Dura Mater and the Effects of Storage Media, Clin. Phys. Physiol. Meas., 2, 197, 10.1088/0143-0815/2/3/003 · doi:10.1088/0143-0815/2/3/003
  51. 1981, A Study of the Uniaxial Mechanical Properties of Human Dura Mater Preserved in Glycerol, Biomaterials, 2, 41, 10.1016/0142-9612(81)90086-7 · DOI
  52. 2002, Computational Study of the Contribution of the Vasculature on the Dynamic Response of the Brain, Stapp Car Crash J., 46, 145
  53. 2006, Biomechanical Properties of the Superior Sagittal Sinus-Bridging Vein Complex, Stapp Car Crash J., 50, 625
  54. 1989, Insensitivity of Tensile Failure Properties of Human Bridging Veins to Strain Rate: Implications in Biomechanics of Subdural Hematoma, J. Biomech., 22, 537
  55. 1974, Dynamic Properties of the Parasagittal Bridging Veins, Z. Rechtsmed., 74, 55, 10.1007/BF01869185 · DOI
  56. 2003, Axial Mechanical Properties of Fresh Human Cerebral Blood Vessels, ASME J. Biomech. Eng., 125, 288, 10.1115/1.1554412 · DOI · Paper page
  57. 2005, Significance of Source and Size in the Mechanical Response of Human Cerebral Blood Vessels, J. Biomech., 38, 737, 10.1016/j.jbiomech.2004.05.004 · DOI · Paper page
  58. 1970, A Comparison of the Elasticity of Live, Dead, and Fixed Brain Tissue, J. Biomech., 3, 453, 10.1016/0021-9290(70)90017-5 · DOI
  59. 1970, A Viscoelastic Study of Scalp, Brain, and Dura, J. Biomech., 3, 211, 10.1016/0021-9290(70)90007-2 · DOI · Paper page
  60. 2010, Fifty Years of Brain Tissue Mechanical Testing: From in vitro to in vivo Investigations, Biorheology, 47, 255
  61. 2008, Rheological Properties of the Tissues of the Central Nervous System: A Review, Med. Eng. Phys., 30, 1318, 10.1016/j.medengphy.2008.06.003 · DOI · Paper page
  62. 2009, Dynamic Mechanical Response of Bovine Gray Matter and White Matter Brain Tissues Under Compression, J. Biomech., 42, 731, 10.1016/j.jbiomech.2009.01.023 · doi:10.1016/j.jbiomech.2009.01.023
  63. 2012, Acoustic Radiation Force Impulse Imaging Improves Ultrasound Resolution in Neural Tissue: Effects of Temperature and Confinement on Brain Material Property Characterization, J. Neurotrauma, 22, A200
  64. 2004, The High Frequency Properties of Brain Tissue, Biorheology, 41, 681
  65. 2012, Transmission, Attenuation and Reflection of Shear Waves in the Human Brain, J. R. Soc. Interface, 9, 2899, 10.1098/rsif.2012.0325 · DOI
  66. 2011, Microscopic Magnetic Resonance Elastography of Traumatic Brain Injury Model, J. Neurosci. Meth., 201, 296, 10.1016/j.jneumeth.2011.08.019 · DOI
  67. 2011, Viscoelastic Properties of Human Cerebellum Using Magnetic Resonance Elastography, J. Biomech., 44, 1909, 10.1016/j.jbiomech.2011.04.034 · DOI
  68. 2010, In vivo Magnetic Resonance Elastography of Human Brain at 7 T and 1.5 T, J. Magn. Reson. Imaging, 32, 577, 10.1002/jmri.22294 · DOI
  69. 2011, A Detailed Viscoelastic Characterization of the P17 and Adult Rat Brain, J. Neurotrauma, 28, 2235, 10.1089/neu.2010.1604 · DOI
  70. 2011, Dynamic, Regional Mechanical Properties of the Porcine Brain: Indentation in the Coronal Plane, ASME J. Biomech. Eng., 133, 071009, 10.1115/1.4004494 · DOI
  71. 2012, Viscoelastic Properties of the Rat Brain in the Sagittal Plane: Effects of Anatomical Structure and Age, Ann. Biomed. Eng., 40, 70, 10.1007/s10439-011-0394-2 · DOI
  72. 2013, Measurements of Mechanical Anisotropy in Brain Tissue and Implications for Transversely Isotropic Material Models of White Matter, J. Mech. Behav. Biomed. Mater., 23, 117, 10.1016/j.jmbbm.2013.04.007 · DOI · Paper page
  73. 2006, Anisotropic Constitutive Equations and Experimental Tensile Behavior of Brain Tissue, Biomech. Model. Mechanobiol., 5, 53, 10.1007/s10237-005-0007-9 · DOI · Paper page
  74. 1998, Material Characterization of the Brainstem From Oscillatory Shear Tests, J. Biomech., 31, 801, 10.1016/S0021-9290(98)00068-2 · DOI · Paper page
  75. 2010, Age-Dependent Regional Mechanical Properties of the Rat Hippocampus and Cortex, ASME J. Biomech. Eng., 132, 011010, 10.1115/1.4000164 · DOI
  76. 2012, High-Strain-Rate Brain Injury Model Using Submerged Acute Rat Brain Tissue Slices, J. Neurotrauma, 29, 418, 10.1089/neu.2011.1772 · DOI
  77. 2011, Effects of Tissue Preservation Temperature on High Strain-Rate Material Properties of Brain, J. Biomech., 44, 391, 10.1016/j.jbiomech.2010.10.024 · doi:10.1016/j.jbiomech.2010.10.024
  78. 2008, How to Test Brain and Brain Simulant at Ballistic and Blast Strain Rates, Biomed. Sci. Instrum., 44, 129
  79. 2003, Modeling of Microstructural Kinematics During Simple Elongation of Central Nervous System Tissue, ASME J. Biomech. Eng., 125, 798, 10.1115/1.1632627 · DOI
  80. 2003, Relationship Between Structural Modeling and Hyperelastic Material Behavior: Application to CNS White Matter, Biomech. Model. Mechanobiol., 1, 279, 10.1007/s10237-002-0020-1 · DOI
  81. 2009, A Micromechanical Hyperelastic Modeling of Brain White Matter Under Large Deformation, J. Mech. Behav. Biomed. Mater., 2, 243, 10.1016/j.jmbbm.2008.08.003 · DOI
  82. 2009, A Micromechanical Procedure for Modelling the Anisotropic Mechanical Properties of Brain White Matter, Comput. Meth. Biomech. Biomed. Eng., 12, 249, 10.1080/10255840802430587 · doi:10.1080/10255840802430587
  83. 2011, A Transition Model for Finite Element Simulation of Kinematics of Central Nervous System White Matter, IEEE Trans. Biomed. Eng., 58, 3443, 10.1109/TBME.2011.2163189 · doi:10.1109/tbme.2011.2163189
  84. 2011, Biomechanics of Single Cortical Neurons, Acta Biomater., 7, 1210, 10.1016/j.actbio.2010.10.018 · DOI
  85. 2010, Neuronal Elasticity as Measured by Atomic Force Microscopy, J. Neurosci. Meth., 186, 35, 10.1016/j.jneumeth.2009.10.021 · DOI
  86. 2005, AFM Study of Hippocampal Cells Cultured on Silicon Wafers With Nano-Scale Surface Topograph, Colloids Surf. B Biointerfaces, 44, 152
  87. 1993, Three-Dimensional Imaging of Living Neurons and Glia With the Atomic Force Microscope, J. Cell Sci., 104, 427, 10.1242/jcs.104.2.427 · DOI
  88. 2009, Mechanically Induced Reactive Gliosis Causes ATP-Mediated Alterations in Astrocyte Stiffness, J. Neurotrauma, 26, 789, 10.1089/neu.2008.0727 · doi:10.1089/neu.2008.0727
  89. 1996, Membrane Deformation of Living Glial Cells Using Atomic Force Microscopy, J. Microsc., 182, 114, 10.1046/j.1365-2818.1996.141423.x · DOI
  90. 1943, Mechanics of Head Injuries, Lancet, 242, 438, 10.1016/S0140-6736(00)87453-X · DOI · Paper page
  91. 1961, Photoelastic Confirmation of the Presence of Shear Strains at the Craniospinal Junction in Closed Head Injury, J. Neurosurg., 18, 58, 10.3171/jns.1961.18.1.0058 · doi:10.3171/jns.1961.18.1.0058
  92. 1990, Physical Model Simulations of Brain Injury in the Primate, J. Biomech., 23, 823, 10.1016/0021-9290(90)90029-3 · DOI · Paper page
  93. 2004, Measurement of Strain in Physical Models of Brain Injury: A Method Based on HARP Analysis of Tagged Magnetic Resonance Images (MRI), ASME J. Biomech. Eng., 126, 523, 10.1115/1.1785811 · DOI
  94. 2002, Influence of the Lateral Ventricles and Irregular Skull Base on Brain Kinematics due to Sagittal Plane Head Rotation, ASME J. Biomech. Eng., 124, 422, 10.1115/1.1485752 · DOI
  95. 2000, Strain Relief From the Cerebral Ventricles During Head Impact: Experimental Studies on Natural Protection of the Brain, J. Biomech., 33, 181, 10.1016/S0021-9290(99)00144-X · doi:10.1016/s0021-9290(99)00144-x
  96. 1994, Modification of the Cortical Impact Model to Produce Axonal Injury in the Rat Cerebral Cortex, J. Neurotrauma, 11, 599, 10.1089/neu.1994.11.599 · DOI
  97. 1992, Biomechanical Aspects of a Fluid Percussion Model of Brain Injury, J. Neurotrauma, 9, 311, 10.1089/neu.1992.9.311 · DOI
  98. 2011, Physics of IED Blast Shock Tube Simulations for mTBI Research, Front. Neurol., 2, 1–14
  99. 2012, Using a Gel/Plastic Surrogate to Study the Biomechanical Response of the Head Under Air Shock Loading: A Combined Experimental and Numerical Investigation, Biomech. Model. Mechanobiol., 11, 341
  100. 2011, Experimental Modeling of Explosive Blast-Related Traumatic Brain Injuries, Neuroimage, 54, S45
  101. 2009, A Finite Element Study of Blast Traumatic Brain Injury—Biomed 2009, Biomed. Sci. Instrum., 45, 119
  102. 2001, Investigation of Head Injury Mechanisms Using Neutral Density Technology and High-Speed Biplanar X-ray, Stapp Car Crash J., 45, 337
  103. 2013, Development of a Miniaturized Position Sensing System for Measuring Brain Motion During Impact—Biomed 2013, Biomed. Sci. Instrum., 49, 281
  104. 2007, A Study of the Response of the Human Cadaver Head to Impact, Stapp Car Crash J., 51, 17
  105. 2001, Recent Advances in Brain Injury Research: A New Human Head Model Development and Validation, Stapp Car Crash J., 45, 369
  106. 2004, The Influence of Surrogate Blood Vessels on the Impact Response of a Physical Model of the Brain, Stapp Car Crash J., 48, 259
  107. 2002, Correlation of an FE Model of the Human Head With Local Brain Motion—Consequences for Injury Prediction, Stapp Car Crash J., 46, 123
  108. 2007, Separating Brain Motion Into Rigid Body Displacement and Deformation Under Low-Severity Impacts, J. Biomech., 40, 1183, 10.1016/j.jbiomech.2006.06.018 · doi:10.1016/j.jbiomech.2006.06.018
  109. 2005, Deformation of the Human Brain Induced by Mild Acceleration, J. Neurotrauma, 22, 845, 10.1089/neu.2005.22.845 · DOI · Paper page
  110. 2008, Deformation of the Human Brain Induced by Mild Angular Head Acceleration, J. Biomech., 41, 307, 10.1016/j.jbiomech.2007.09.016 · DOI · Paper page
  111. 1996, Finite-Element Models of the Human Head, Med. Biol. Eng. Comput., 34, 375, 10.1007/BF02520009 · doi:10.1007/bf02520009
  112. 1995, Recent Advances in Biomechanics of Brain Injury Research: a Review, J. Neurotrauma, 12, 651, 10.1089/neu.1995.12.651 · doi:10.1089/neu.1995.12.651
  113. 2013, Development of a Finite Element Human Head Model Validated With Forty Nine Loading Cases From Experimental and Real World Impacts, ASME J. Biomech. Eng, 135, 111002, 10.1115/1.4025101 · DOI · Paper page
  114. 2013, The Dynamic Triple Peak Impact Factor in Traumatic Brain Injury Influences Native Protein Structures in Gray and White Matter as Measured With Computational Simulation, Neurol. Res., 35, 782–789
  115. 2013, Methodology to Determine Skull Bone and Brain Responses From Ballistic Helmet-to-Head Contact Loading Using Experiments and Finite Element Analysis, Med. Eng. Phys., 135, 1682–1687
  116. 2013, Evaluation of the Extent and Distribution of Diffuse— Axonal Injury From Real World Motor Vehicle CrashesBiomed 2013, Biomed. Sci. Instrum., 49, 297
  117. 2012, Research of the Relationship of Pedestrian Injury to Collision Speed, Car-Type, Impact Location and Pedestrian Sizes Using Human FE Model (THUMS Version 4), Stapp Car Crash J., 56, 269
  118. 2013, The Biomechanical Determinants of Concussion: Finite Element Simulations to Investigate Brain Tissue Deformations During Sporting Impacts to the Unprotected Head, J. Appl. Biomech
  119. 2013, A Computational Study of Influence of Helmet Padding Materials on the Human Brain Under Ballistic Impacts, Comput. Meth. Biomech. Biomed. Eng
  120. 2012, Human Head-Neck Computational Model for Assessing Blast Injury, J. Biomech., 45, 2899, 10.1016/j.jbiomech.2012.07.027 · doi:10.1016/j.jbiomech.2012.07.027
  121. 2013, A Multiscale Computational Approach to Estimating Axonal Damage Under Inertial Loading of the Head, J. Neurotrauma, 30, 102, 10.1089/neu.2012.2418 · DOI
  122. 2011, Study of Mild Traumatic Brain Injuries Using Experiments and Finite Element Modeling, Ann. Adv. Automot. Med., 55, 125
  123. 2012, A Tissue-Level Anisotropic Criterion for Brain Injury Based on Microstructural Axonal Deformation, J. Mech. Behav. Biomed. Mater., 5, 41, 10.1016/j.jmbbm.2011.09.012 · DOI
  124. 2011, Computation of Axonal Elongation in Head Trauma Finite Element Simulation, J. Mech. Behav. Biomed. Mater., 4, 1905, 10.1016/j.jmbbm.2011.06.007 · DOI
  125. 2012, Mild Traumatic Brain Injury Predictors Based on Angular Accelerations During Impacts, Ann. Biomed. Eng., 40, 114, 10.1007/s10439-011-0414-2 · DOI · Paper page
  126. 2012, Maximum Principal Strain and Strain Rate Associated With Concussion Diagnosis Correlates With Changes in Corpus Callosum White Matter Indices, Ann. Biomed. Eng., 40, 127, 10.1007/s10439-011-0402-6 · DOI
  127. 2012, Role of Helmet in the Mechanics of Shock Wave Propagation Under Blast Loading Conditions, Comput. Meth. Biomech. Biomed. Eng., 15, 1233, 10.1080/10255842.2011.597353 · doi:10.1080/10255842.2011.597353
  128. 2012, An Axonal Strain Injury Criterion for Traumatic Brain Injury, Biomech. Model. Mechanobiol., 11, 245
  129. 2011, A Modified Human Head Model for the Study of Impact Head Injury, Comput. Meth. Biomech. Biomed. Eng., 14, 1049, 10.1080/10255842.2010.506435 · doi:10.1080/10255842.2010.506435
  130. 2010, In Silico Investigation of Intracranial Blast Mitigation With Relevance to Military Traumatic Brain Injury, Proc. Natl. Acad. Sci. USA, 107, 20703, 10.1073/pnas.1014786107 · DOI
  131. 2010, Applying DTI White Matter Orientations to Finite Element Head Models to Examine Diffuse TBI Under High Rotational Accelerations, Prog. Biophys. Mol. Biol., 103, 304
  132. 2011, Investigation of Head Response to Blast Loading, J. Trauma, 70, E29, 10.1097/TA.0b013e3181de3f4b · DOI
  133. 2010, Computational Model of the Cerebral Ventricles in Hydrocephalus, ASME J. Biomech. Eng., 132, 054501, 10.1115/1.4001025 · doi:10.1115/1.4001025
  134. 2009, A Finite Element Model of Region-Specific Response for Mild Diffuse Brain Injury, Stapp Car Crash J., 53, 193
  135. 2010, Biomechanical Assessment of Brain Dynamic Responses due to Blast Pressure Waves, Ann. Biomed. Eng., 38, 490, 10.1007/s10439-009-9813-z · DOI · Paper page
  136. 2009, Computational Biology—Modeling of Primary Blast Effects on the Central Nervous System, Neuroimage, 47, T10
  137. 2007, Influence of Impact Speed on Head and Brain Injury Outcome in Vulnerable Road User Impacts to the Car Hood, Stapp Car Crash J., 51, 155
  138. 2007, Predictors for Traumatic Brain Injuries Evaluated Through Accident Reconstructions, Stapp Car Crash J., 51, 81
  139. 2006, Finite Element Analysis and Experimental Study on Mechanism of Brain Injury Using Brain Model, Conf, Proc, IEEE Eng. Med. Biol. Soc., 1, 1327
  140. 2007, Concussion in Professional Football: Biomechanics of the Struck Player—part 14, Neurosurgery, 61, 313, 10.1227/01.NEU.0000279969.02685.D0 · DOI · Paper page
  141. 2007, 3-D Finite Element Analysis and Experimental Study on Brain Injury Mechanism, Conf. Proc. IEEE Eng. Med. Biol. Soc., 3613
  142. 2004, A Proposed Injury Threshold for Mild Traumatic Brain Injury, ASME J. Biomech. Eng., 126, 226, 10.1115/1.1691446 · DOI · Paper page
  143. 2005, Concussion in Professional Football: Brain Responses by Finite Element Analysis: Part 9, Neurosurgery, 57, 891, 10.1227/01.NEU.0000186950.54075.3B · DOI · Paper page
  144. 2012, Minimization of Analytical Injury Metrics for Head Impact Injuries, Traffic Inj. Prev., 13, 278, 10.1080/15389588.2011.650803 · doi:10.1080/15389588.2011.650803
  145. 2009, Every Newton Hertz: A Macro to Micro Approach to Investigating Brain Injury, Conf. Proc. IEEE Eng. Med. Biol. Soc., 1123
  146. 2009, Evaluation of the Biofidelity of FMVSS No. 218 Injury Criteria, Traffic Inj. Prev., 10, 170, 10.1080/15389580802607796 · doi:10.1080/15389580802607796
  147. 2008, Age and Gender Based Biomechanical Shape and Size Analysis of the Pediatric Brain, Stapp Car Crash J., 52, 59
  148. 2008, Investigation of Traumatic Brain Injuries Using the Next Generation of Simulated Injury Monitor (SIMon) Finite Element Head Model, Stapp Car Crash J., 52, 1
  149. 2005, Analysis of Finite Element Models for Head Injury Investigation: Reconstruction of Four Real-World Impacts, Stapp Car Crash J., 49, 1
  150. 2003, On the Development of the SIMon Finite Element Head Model, Stapp Car Crash J., 47, 107
  151. 2006, Role of Translational and Rotational Accelerations on Brain Strain in Lateral Head Impact, Biomed. Sci. Instrum., 42, 501
  152. 2013, Computational Modeling of Human Head Under Blast in Confined and Open Spaces: Primary Blast Injury, Int. J. Num. Method Biomed Eng
  153. 2013, Brain Response to Primary Blast Wave Using Validated Finite Element Models of Human Head and Advanced Combat Helmet, Front Neurol., 4, 1–12
  154. 2012, Blast-Induced Biomechanical Loading of the Rat: an Experimental and Anatomically Accurate Computational Blast Injury Model, J. Neurotrauma, 29, 2352, 10.1089/neu.2012.2413 · DOI
  155. 2012, Development of a Finite Element Model for Blast Brain Injury and the Effects of CSF Cavitation, Ann. Biomed. Eng., 40, 1530, 10.1007/s10439-012-0519-2 · DOI · Paper page
  156. 2006, Application of a Finite Element Model of the Brain to Study Traumatic Brain Injury Mechanisms in the Rat, Stapp Car Crash J., 50, 583
  157. 2006, Computational Studies of Strain Exposures in Neonate and Mature Rat Brains During Closed Head Impact, J. Neurotrauma, 23, 1570, 10.1089/neu.2006.23.1570 · DOI
  158. 2005, Brain Tissue Biomechanics in Cortical Contusion Injury: a Finite Element Analysis, Acta Neurochir. Suppl., 95, 333, 10.1007/3-211-32318-X_68 · doi:10.1007/3-211-32318-x_68
  159. 2003, Age-Dependent Changes in Material Properties of the Brain and Braincase of the Rat, J. Neurotrauma, 20, 1163, 10.1089/089771503770802853 · DOI · Paper page
  160. 2013, Biomechanical Responses of a Pig Head Under Blast Loading: a Computational Simulation, Int. J. Num. Meth. Biomed. Eng., 29, 392, 10.1002/cnm.2518 · DOI
  161. 2012, Finite Element Model Predictions of Intracranial Hemorrhage From Non-Impact, Rapid Head Rotations in the Piglet, Int. J. Dev. Neurosci., 30, 191, 10.1016/j.ijdevneu.2011.12.009 · DOI
  162. 2006, Predicting Unconsciousness From a Pediatric Brain Injury Threshold, Dev. Neurosci., 28, 388
  163. 2006, Material Properties of Porcine Parietal Cortex, J. Biomech., 39, 2521, 10.1016/j.jbiomech.2005.07.020 · doi:10.1016/j.jbiomech.2005.07.020
  164. 2000, Infant Skull and Suture Properties: Measurements and Implications for Mechanisms of Pediatric Brain Injury, ASME J. Biomech. Eng., 122, 364, 10.1115/1.1287160 · DOI · Paper page
  165. 2013, Mechanical Properties of the Brain-Skull Interface, Acta Bioeng. Biomech., 15, 3
  166. 2011, Finite Element Analysis of Ramming in Ovis canadensis, ASME J. Biomech. Eng., 133, 021009, 10.1115/1.4003321 · doi:10.1115/1.4003321
  167. 2003, Impact Mechanics and Axonal Injury in a Sheep Model, J. Neurotrauma, 20, 961, 10.1089/089771503770195812 · DOI
  168. 2010, Computational Neurotrauma—Design, Simulation, and Analysis of Controlled Cortical Impact Model, Biomech. Model. Mechanobiol., 9, 763, 10.1007/s10237-010-0212-z · DOI
  169. 2011, Quantitative Relationship Between Axonal Injury and Mechanical Response in a Rodent Head Impact Acceleration Model, J. Neurotrauma, 28, 1767, 10.1089/neu.2010.1687 · DOI
  170. 2009, Structural and Functional Changes in Nerve Roots due to Tension at Various Strains and Strain Rates: an in-vivo Study, J. Neurotrauma, 26, 627, 10.1089/neu.2008.0621 · DOI
  171. 2006, A New Model of Traumatic Axonal Injury to Determine the Effects of Strain and Displacement Rates, Stapp Car Crash J., 50, 601
  172. 2001, Dynamic Stretch Correlates to Both Morphological Abnormalities and Electrophysiological Impairment in a Model of Traumatic Axonal Injury, J. Neurotrauma, 18, 499, 10.1089/089771501300227305 · DOI
  173. 2000, Tissue-Level Thresholds for Axonal Damage in an Experimental Model of Central Nervous System White Matter Injury, ASME J. Biomech. Eng., 122, 615, 10.1115/1.1324667 · DOI · Paper page
  174. 2006, High Rate Shear Insult Delivered to Cortical Neurons Produces Heterogeneous Membrane Permeability Alterations, Conf. Proc. IEEE Eng. Med. Biol. Soc., 1, 2384
  175. 2008, Shear-Induced Intracellular Loading of Cells With Molecules by Controlled Microfluidics, Biotechnol. Bioeng., 99, 846, 10.1002/bit.21651 · DOI
  176. 2005, High Rate Shear Strain of Three-Dimensional Neural Cell Cultures: A New in vitro Traumatic Brain Injury Model, J. Biomech., 38, 1093, 10.1016/j.jbiomech.2004.05.032 · DOI · Paper page
  177. 2003, Susceptibility of Hippocampal Neurons to Mechanically Induced Injury, Exp. Neurol., 184, 420, 10.1016/S0014-4886(03)00254-1 · DOI
  178. 1996, Stretch-Induced Injury of Cultured Neuronal, Glial, and Endothelial Cells. Effect of Polyethylene Glycol-Conjugated Superoxide Dismutase, Stroke, 27, 934, 10.1161/01.STR.27.5.934 · DOI
  179. 2004, Effect of Acute Calcium Influx After Mechanical Stretch Injury in vitro on the Viability of Hippocampal Neurons, J. Neurotrauma, 21, 61, 10.1089/089771504772695959 · DOI
  180. 2007, Linking Impact to Cellular and Molecular Sequelae of CNS Injury: Modeling in vivo Complexity With in vitro Simplicity, Prog. Brain Res., 161, 27, 10.1016/S0079-6123(06)61003-0 · DOI
  181. 2013, Stretch Injury Selectively Enhances Extrasynaptic, GluN2B-Containing NMDA Receptor Function in Cortical Neurons, J. Neurophysiol., 110, 131, 10.1152/jn.01011.2012 · DOI
  182. 2004, Mechanical Injury Modulates AMPA Receptor Kinetics via an NMDA Receptor-Dependent Pathway, J. Neurotrauma, 21, 719, 10.1089/0897715041269704 · DOI
  183. 2004, Potentiation of GABA(A) Currents After Mechanical Injury of Cortical Neurons, J. Neurotrauma, 21, 259, 10.1089/089771504322972059 · DOI
  184. 2000, Mechanical Injury Alters Volume Activated Ion Channels in Cortical Astrocytes, Acta Neurochir. Suppl., 76, 379, 10.1007/978-3-7091-6346-7_79 · DOI
  185. 1999, Enhancement of AMPA-Mediated Current After Traumatic Injury in Cortical Neurons, J. Neurosci., 19, 7367, 10.1523/JNEUROSCI.19-17-07367.1999 · DOI
  186. 2012, N-methyl-D-aspartate Receptor Mechanosensitivity is Governed by C Terminus of NR2B Subunit, J. Biol. Chem., 287, 4348, 10.1074/jbc.M111.253740 · DOI
  187. 2009, Mechanical Membrane Injury Induces Axonal Beading Through Localized Activation of Calpain, Exp. Neurol., 219, 553, 10.1016/j.expneurol.2009.07.014 · DOI
  188. 2008, Mechanically-Induced Membrane Poration Causes Axonal Beading and Localized Cytoskeletal Damage, Exp. Neurol., 212, 422, 10.1016/j.expneurol.2008.04.025 · DOI · Paper page
  189. 2005, Mechanical Cell Injury, Ann. NY Acad. Sci., 1066, 67, 10.1196/annals.1363.006 · DOI
  190. 2011, Trauma-Induced Plasmalemma Disruptions in Three-Dimensional Neural Cultures Are Dependent on Strain Modality and Rate, J. Neurotrauma, 28, 2219, 10.1089/neu.2011.1841 · DOI
  191. 2009, Plasma Membrane Damage as a Marker of Neuronal Injury, Conf. Proc. IEEE Eng. Med. Biol. Soc., 1113
  192. 2003, Mechanical Stretch to Neurons Results in a Strain Rate and Magnitude-Dependent Increase in Plasma Membrane Permeability, J. Neurotrauma, 20, 1039, 10.1089/089771503770195885 · DOI · Paper page
  193. 1998, Dynamic Mechanical Deformation of Neurons Triggers an Acute Calcium Response and Cell Injury Involving the N-methyl-D-aspartate glutamate Receptor, J. Neurosci. Res., 52, 220, 10.1002/(SICI)1097-4547(19980415)52:2<220::AID-JNR10>3.0.CO;2-B · doi:10.1002/(sici)1097-4547(19980415)52:2<220::aid-jnr10>3.0.co;2-b
  194. 2013, Blood-Brain Barrier Dysfunction After Primary Blast Injury in vitro, J. Neurotrauma., 30, 1652–1663
  195. 2012, A Multiscale Approach to Blast Neurotrauma Modeling: Part I—Development of Novel Test Devices for in vivo and in vitro Blast Injury Models, Front. Neurol., 3, 1–11
  196. 2012, Transient Changes in Neuronal Cell Membrane Permeability After Blast Exposure, Neuroreport, 23, 342, 10.1097/WNR.0b013e328351b58d · doi:10.1097/wnr.0b013e328351b58d
  197. 2012, An in vitro Injury Model for SH-SY5Y Neuroblastoma Cells: effect of Strain and Strain Rate, J. Neurosci. Meth., 205, 159, 10.1016/j.jneumeth.2012.01.001 · DOI
  198. 2011, Impulsive Pressurization of Neuronal Cells for Traumatic Brain Injury Study, J. Vis. Exp., 56, 1–4
  199. 2011, Blast-Induced Phenotypic Switching in Cerebral Vasospasm, Proc. Natl. Acad. Sci. USA, 108, 12705, 10.1073/pnas.1105860108 · DOI
  200. 2011, Studies on Blast Traumatic Brain Injury Using in-vitro Model With Shock Tube, Neuroreport, 22, 379, 10.1097/WNR.0b013e328346b138 · doi:10.1097/wnr.0b013e328346b138

200 of 228 shown

Cited by

See all 247

Metadata

Authors
Meaney, D. F., Morrison, B., & Dale Bass, C.
Venue
Journal of Biomechanical Engineering
Publisher
ASME International
Published
2014-02-01
Volume
136
Issue
2
Pages
021008-021008
ISSN
  • 0148-0731 (ISSN-L)
  • 1528-8951
DOI
10.1115/1.4026364
OpenAlex
W2079164954
Cited by
247
References
10
FWCI
11.39
Type
journal article
Language
en
Open access
bronze

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: The Mechanics of Traumatic Brain Injury: A Review of What We Know and What We Need to Know for Reducing Its Societal Burden. https://app.cochat.ai/papers/10.1115/1.4026364
The paper
Meaney, D. F., Morrison, B., & Dale Bass, C. (2014). The Mechanics of Traumatic Brain Injury: A Review of What We Know and What We Need to Know for Reducing Its Societal Burden. Journal of Biomechanical Engineering. https://doi.org/10.1115/1.4026364

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.