Cited by 120Muscle metabolism and nutritionSports Performance and TrainingNutrition and Health in Aging

No Difference Between the Effects of Supplementing With Soy Protein Versus Animal Protein on Gains in Muscle Mass and Strength in Response to Resistance Exercise

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Messina, Mark, Lynch, Heidi, Dickinson, Jared M., Reed, Katharine E.·2018·International Journal of Sport Nutrition and Exercise Metabolism

Abstract

Much attention has been given to determining the influence of total protein intake and protein source on gains in lean body mass (LBM) and strength in response to resistance exercise training (RET). Acute studies indicate that whey protein, likely related to its higher leucine content, stimulates muscle protein synthesis to a greater extent than proteins such as soy and casein. Less clear is the extent to which the type of protein supplemented impacts strength and LBM in long-term studies (≥6 weeks). Therefore, a meta-analysis was conducted to compare the effect of supplementation with soy protein to animal protein supplementation on strength and LBM in response to RET. Nine studies involving 266 participants suitable for inclusion in the meta-analysis were identified. Five studies compared whey with soy protein, and four studies compared soy protein with other proteins (beef, milk, or dairy protein). Meta-analysis showed that supplementing RET with whey or soy protein resulted in significant increases in strength but found no difference between groups (bench press: χ 2 = 0.02, p = .90; squat: χ 2 = 0.22, p = .64). There was no significant effect of whey or soy alone (n = 5) on LBM change and no differences between groups (χ 2 = 0.00, p = .96). Strength and LBM both increased significantly in the “other protein” and the soy groups (n = 9), but there were no between-group differences (bench: χ 2 = 0.02, p = .88; squat: χ 2 = 0.78, p = .38; and LBM: χ 2 = 0.06, p = .80). The results of this meta-analysis indicate that soy protein supplementation produces similar gains in strength and LBM in response to RET as whey protein.

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Authors
Messina, M., Lynch, H., Dickinson, J. M., & Reed, K. E.
Affiliations
  • Nutrition Matters, Inc.
  • Point Loma Nazarene University (US)
  • Arizona State University (US)
  • University of Essex (GB)
Venue
International Journal of Sport Nutrition and Exercise Metabolism
Published
2018-11-01
Volume
28
Issue
6
Pages
674-685
ISSN
  • 1526-484X (ISSN-L)
  • 1543-2742
OpenAlex
W2800163167
Cited by
120
References
96
Citations by year
2026: 14 · 2025: 18 · 2024: 23 · 2023: 17 · 2022: 18 · 2021: 20 · 2020: 9 · 2019: 1
FWCI
0.84
Type
journal article
Language
en
Open access
Locations
  • International Journal of Sport Nutrition and Exercise Metabolism (publishedVersion)
  • PubMed (publishedVersion)
  • Open Access at Essex (University of Essex) (acceptedVersion)
Funders
Soy Nutrition Institute
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
Keywords
whey protein, resistance training, lean body mass, muscle strength, protein sources, muscle protein synthesis, leucine, bench press, squatting
MeSH terms
Whey Proteins, Humans, Body Mass Index, Muscle, Skeletal, Dietary Supplements, Soybean Proteins, Muscle Strength, Resistance Training

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