Pharmacological Agents That Directly Modulate Insulin Secretion

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

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Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin

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Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus* (2002) · Diabetes Care · doi:10.2337/diacare.25.2007.s5 · Cited by 10,338

The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity

Doyle, D. A., Cabral, J. M., Pfuetzner, R. A., Kuo, A., Gulbis, J. M., Cohen, S. L., Chait, B. T., & MacKinnon, R. (1998) · Science · doi:10.1126/science.280.5360.69 · Cited by 6,807

The mechanisms of action of PPARs

Berger, J., & Moller, D. E. (2002) · Annual Review of Medicine · doi:10.1146/annurev.med.53.082901.104018 · Cited by 2,659

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

Rao, A., Luo, C., & Hogan, P. G. (1997) · Annual Review of Immunology · doi:10.1146/annurev.immunol.15.1.707 · Cited by 2,603

The mitochondrial permeability transition pore and its role in cell death

CROMPTON, M. (1999) · Biochemical Journal · doi:10.1042/bj3410233 · Cited by 2,432

Insulin-promoter-factor 1 is required for pancreas development in mice

Jonsson, J., Carlsson, L., Edlund, T., & Edlund, H. (1994) · Nature · doi:10.1038/371606a0 · Cited by 1,785

Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms

Beavo, J. A. (1995) · Physiological Reviews · doi:10.1152/physrev.1995.75.4.725 · Cited by 1,767

Kinesin and Dynein Superfamily Proteins and the Mechanism of Organelle Transport

Hirokawa, N. (1998) · Science · doi:10.1126/science.279.5350.519 · Cited by 1,686

Somatostatin and Its Receptor Family

Patel, Y. C. (1999) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1999.0183 · Cited by 1,648

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

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Calcineurin: Form and Function

Rusnak, F., & Mertz, P. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.4.1483 · Cited by 1,373

NFAT Signaling

Crabtree, G. R., & Olson, E. N. (2002) · Cell · doi:10.1016/s0092-8674(02)00699-2 · Cited by 1,323

Pharmacologic Therapy for Type 2 Diabetes Mellitus

DeFronzo, R. A. (1999) · Annals of Internal Medicine · doi:10.7326/0003-4819-131-4-199908170-00008 · Cited by 1,173

Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d‐tubocurarine

Sheiner, L. B., Stanski, D. R., Vozeh, S., Miller, R. D., & Ham, J. (1979) · Clinical Pharmacology & Therapeutics · doi:10.1002/cpt1979253358 · Cited by 1,134

Electrophysiology of the pancreatic β-cell

Ashcroft, F. M., & Rorsman, P. (1989) · Progress in Biophysics and Molecular Biology · doi:10.1016/0079-6107(89)90013-8 · Cited by 1,127

Oral Antihyperglycemic Therapy for Type 2 Diabetes: Scientific Review

Inzucchi, S. E. (2002) · JAMA · doi:10.1001/jama.287.3.360 · Cited by 1,065

A New ER Trafficking Signal Regulates the Subunit Stoichiometry of Plasma Membrane KATP Channels

Zerangue, N., Schwappach, B., Jan, Y. N., & Jan, L. Y. (1999) · Neuron · doi:10.1016/s0896-6273(00)80708-4 · Cited by 1,025

Octreotide

Lamberts, S. W. J., van der Lely, A.-J., de Herder, W. W., & Hofland, L. J. (1996) · New England Journal of Medicine · doi:10.1056/nejm199601253340408 · Cited by 1,001

Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas.

Eng, J., Kleinman, W. A., Singh, L., Singh, G., & Raufman, J. P. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42531-8 · Cited by 1,000

Glycosylation of Nucleocytoplasmic Proteins: Signal Transduction and O-GlcNAc

Wells, L., Vosseller, K., & Hart, G. W. (2001) · Science · doi:10.1126/science.1058714 · Cited by 954

Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line.

Drucker, D. J., Philippe, J., Mojsov, S., Chick, W. L., & Habener, J. F. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.10.3434 · Cited by 903

Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.

Göke, R., Fehmann, H. C., Linn, T., Schmidt, H., Krause, M., Eng, J., & Göke, B. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)36565-2 · Cited by 837

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A.

Fruman, D. A., Klee, C. B., Bierer, B. E., & Burakoff, S. J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.9.3686 · Cited by 823

Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion

Prentki, M., & Matschinsky, F. M. (1987) · Physiological Reviews · doi:10.1152/physrev.1987.67.4.1185 · Cited by 774

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing

Mojsov, S., Heinrich, G., Wilson, I. B., Ravazzola, M., Orci, L., & Habener, J. F. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67324-7 · Cited by 724

Molecular Biology of Adenosine Triphosphate-Sensitive Potassium Channels*

Aguilar-Bryan, L., & Bryan, J. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.2.0361 · Cited by 698

Association and Stoichiometry of KATP Channel Subunits

Clement, J. P., Kunjilwar, K., Gonzalez, G., Schwanstecher, M., Panten, U., Aguilar-Bryan, L., & Bryan, J. (1997) · Neuron · doi:10.1016/s0896-6273(00)80321-9 · Cited by 692

Randomised trial comparing tacrolimus (FK506) and cyclosporin in prevention of liver allograft rejection

(1994) · The Lancet · doi:10.1016/s0140-6736(94)91766-3 · Cited by 656

Association of Diabetes Mellitus With Use of Atypical Neuroleptics in the Treatment of Schizophrenia

Sernyak, M. J., Leslie, D. L., Alarcon, R. D., Losonczy, M. F., & Rosenheck, R. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.4.561 · Cited by 623

Association of Protein Kinase A and Protein Phosphatase 2B with a Common Anchoring Protein

Coghlan, V. M., Perrino, B. A., Howard, M., Langeberg, L. K., Hicks, J. B., Gallatin, W. M., & Scott, J. D. (1995) · Science · doi:10.1126/science.7528941 · Cited by 617

Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion

Ballinger, S. W., Shoffner, J. M., Hedaya, E. V., Trounce, I., Polak, M. A., Koontz, D. A., & Wallace, D. C. (1992) · Nature Genetics · doi:10.1038/ng0492-11 · Cited by 613

A Dose-Dependent Increase in Mortality with Vesnarinone among Patients with Severe Heart Failure

Cohn, J. N., Goldstein, S. O., Greenberg, B. H., Lorell, B. H., Bourge, R. C., Jaski, B. E., Gottlieb, S. O., McGrew, F., DeMets, D. L., & White, B. G. (1998) · New England Journal of Medicine · doi:10.1056/nejm199812173392503 · Cited by 613

Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death

Duchen, M. R. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.001aa.x · Cited by 610

Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas.

Stoffers, D. A., Kieffer, T. J., Hussain, M. A., Drucker, D. J., Bonner-Weir, S., Habener, J. F., & Egan, J. M. (2000) · Diabetes · doi:10.2337/diabetes.49.5.741 · Cited by 576

Membrane Phospholipid Control of Nucleotide Sensitivity of K ATP Channels

Shyng, S.-L., & Nichols, C. G. (1998) · Science · doi:10.1126/science.282.5391.1138 · Cited by 559

Ramipril and the Development of Diabetes

Yusuf, S. (2001) · JAMA · doi:10.1001/jama.286.15.1882 · Cited by 541

Mitochondria as a Pharmacological Target

Szewczyk, A., & Wojtczak, L. (2002) · Pharmacological Reviews · doi:10.1124/pr.54.1.101 · Cited by 538

Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression

Timmerman, L. A., Clipstone, N. A., Ho, S. N., Northrop, J. P., & Crabtree, G. R. (1996) · Nature · doi:10.1038/383837a0 · Cited by 528

Abnormalities in Glucose Regulation During Antipsychotic Treatment of Schizophrenia

Newcomer, J. W., Haupt, D. W., Fucetola, R., Melson, A. K., Schweiger, J. A., Cooper, B. P., & Selke, G. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.4.337 · Cited by 520

PIP 2 and PIP as Determinants for ATP Inhibition of K ATP Channels

Baukrowitz, T., Schulte, U., Oliver, D., Herlitze, S., Krauter, T., Tucker, S. J., Ruppersberg, J. P., & Fakler, B. (1998) · Science · doi:10.1126/science.282.5391.1141 · Cited by 513

The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men

Agersø, H., Jensen, L. B., Elbrønd, B., Rolan, P., & Zdravkovic, M. (2002) · Diabetologia · doi:10.1007/s00125-001-0719-z · Cited by 510

Mechanisms and Physiological Significance of the Cholinergic Control of Pancreatic β-Cell Function

Gilon, P., & Henquin, J.-C. (2001) · Endocrine Reviews · doi:10.1210/edrv.22.5.0440 · Cited by 508

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis

Maechler, P., & Wollheim, C. B. (1999) · Nature · doi:10.1038/45280 · Cited by 507

mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module

Dodge, K. L. (2001) · The EMBO Journal · doi:10.1093/emboj/20.8.1921 · Cited by 507

Biological actions and therapeutic potential of the glucagon-like peptides

Drucker, D. J. (2002) · Gastroenterology · doi:10.1053/gast.2002.31068 · Cited by 500

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion.

Prentki, M., Vischer, S., Glennon, M. C., Regazzi, R., Deeney, J. T., & Corkey, B. E. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)42624-5 · Cited by 442

Glucagon-Like Peptide-1 Induces Cell Proliferation and Pancreatic-Duodenum Homeobox-1 Expression and Increases Endocrine Cell Mass in the Pancreas of Old, Glucose-Intolerant Rats

Perfetti, R. (2000) · Endocrinology · doi:10.1210/en.141.12.4600 · Cited by 442

Calcium, Calcineurin, and the Control of Transcription

Crabtree, G. R. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.r000024200 · Cited by 440

ATP-sensitive K + channels and insulin secretion: their role in health and disease

Ashcroft, F. M., & Gribble, F. M. (1999) · Diabetologia · doi:10.1007/s001250051247 · Cited by 429

Severe Hypoglycemia and Hyperinsulinemia in Falciparum Malaria

White, N. J., Warrell, D. A., Chanthavanich, P., Looareesuwan, S., Warrell, M. J., Krishna, S., Williamson, D. H., & Turner, R. C. (1983) · New England Journal of Medicine · doi:10.1056/nejm198307143090201 · Cited by 413

Smoking and diabetes

Haire-Joshu, D., Glasgow, R. E., & Tibbs, T. L. (1999) · Diabetes Care · doi:10.2337/diacare.22.11.1887 · Cited by 381

A long-term comparison of tacrolimus (FK506) and cyclosporine in kidney transplantation: evidence for improved allograft survival at five years1

Vincenti, F., Jensik, S. C., Filo, R. S., Miller, J., & Pirsch, J. (2002) · Transplantation · doi:10.1097/00007890-200203150-00021 · Cited by 375

Cellular functions of immunophilins

Marks, A. R. (1996) · Physiological Reviews · doi:10.1152/physrev.1996.76.3.631 · Cited by 367

O-Glycosylation of Nuclear and Cytosolic Proteins

Comer, F. I., & Hart, G. W. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.r000010200 · Cited by 361

Somatostatin Inhibits Insulin and Glucagon Secretion via Two Receptor Subtypes: An in Vitro Study of Pancreatic Islets from Somatostatin Receptor 2 Knockout Mice

Strowski, M. Z. (2000) · Endocrinology · doi:10.1210/en.141.1.111 · Cited by 359

Regulation of insulin gene transcription

Melloul, D., Marshak, S., & Cerasi, E. (2002) · Diabetologia · doi:10.1007/s00125-001-0728-y · Cited by 358

Calcium and GTP: essential components in vesicular trafficking between the endoplasmic reticulum and Golgi apparatus.

Beckers, C. J., & Balch, W. E. (1989) · The Journal of cell biology · doi:10.1083/jcb.108.4.1245 · Cited by 351

Overexpression of glutamine:fructose-6-phosphate amidotransferase in transgenic mice leads to insulin resistance.

Hebert, L. F., Daniels, M. C., Zhou, J., Crook, E. D., Turner, R. L., Simmons, S. T., Neidigh, J. L., Zhu, J. S., Baron, A. D., & McClain, D. A. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118876 · Cited by 335

Activation of the Hexosamine Pathway Leads to Deterioration of Pancreatic β-Cell Function through the Induction of Oxidative Stress

Kaneto, H., Xu, G., Song, K.-H., Suzuma, K., Bonner-Weir, S., Sharma, A., & Weir, G. C. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m104115200 · Cited by 327

The β cell transcription factors and development of the pancreas

Sander, M., & German, M. S. (1997) · Journal of Molecular Medicine · doi:10.1007/s001090050118 · Cited by 318

Smoking as a Modifiable Risk Factor for Type 2 Diabetes in Middle-Aged Men

Wannamethee, S. G., Shaper, A. G., & Perry, I. J. (2001) · Diabetes Care · doi:10.2337/diacare.24.9.1590 · Cited by 314

Stimulation of insulin release by repaglinide and glibenclamide involves both common and distinct processes.

Fuhlendorff, J., Rorsman, P., Kofod, H., Brand, C. L., Rolin, B., MacKay, P., Shymko, R., & Carr, R. D. (1998) · Diabetes · doi:10.2337/diabetes.47.3.345 · Cited by 310

The insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (7–37) in normal and diabetic subjects

Elahi, D., McAloon-Dyke, M., Fukagawa, N. K., Meneilly, G. S., Sclater, A. L., Minaker, K. L., Habener, J. F., & Andersen, D. K. (1994) · Regulatory Peptides · doi:10.1016/0167-0115(94)90136-8 · Cited by 309

Mitochondria and Ca2+in cell physiology and pathophysiology

Duchen, M. R. (2000) · Cell Calcium · doi:10.1054/ceca.2000.0170 · Cited by 309

Exendin-4 Decelerates Food Intake, Weight Gain, and Fat Deposition in Zucker Rats

Szayna, M. (2000) · Endocrinology · doi:10.1210/en.141.6.1936 · Cited by 303

Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

Deacon, C. F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O., & Holst, J. J. (1998) · Diabetologia · doi:10.1007/s001250050903 · Cited by 303

Protein kinase A‐dependent and ‐independent stimulation of exocytosis by cAMP in mouse pancreatic B‐cells

Renström, E., Eliasson, L., & Rorsman, P. (1997) · The Journal of Physiology · doi:10.1111/j.1469-7793.1997.105bl.x · Cited by 299

Co-localization of L-type Ca2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells.

Bokvist, K., Eliasson, L., Ammälä, C., Renström, E., & Rorsman, P. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb06974.x · Cited by 292

Influence of Long-term, Low-Dose, Diuretic-Based, Antihypertensive Therapy on Glucose, Lipid, Uric Acid, and Potassium Levels in Older Men and Women With Isolated Systolic Hypertension<subtitle>The Systolic Hypertension in the Elderly Program</subtitle>

Savage, P. J. (1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.7.741 · Cited by 292

Risk for posttransplant diabetes mellitus with current immunosuppressive medications

Weir, M. R., & Fink, J. C. (1999) · American Journal of Kidney Diseases · doi:10.1016/s0272-6386(99)70101-0 · Cited by 289

Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis.

Kumar, U., Sasi, R., Suresh, S., Patel, A., Thangaraju, M., Metrakos, P., Patel, S. C., & Patel, Y. C. (1999) · Diabetes · doi:10.2337/diabetes.48.1.77 · Cited by 284

The Diagnosis and Management of Hypertensive Crises

Varon, J., & Marik, P. E. (2000) · Chest · doi:10.1378/chest.118.1.214 · Cited by 274

RACIAL DIFFERENCES IN RENAL TRANSPLANTATION AFTER IMMUNOSUPPRESSION WITH TACROLIMUS VERSUS CYCLOSPORINE1

Neylan, J. F. (1998) · Transplantation · doi:10.1097/00007890-199802270-00011 · Cited by 271

Drug-Induced Hypoglycemia: A Review of 1418 Cases

Seltzer, H. S. (1989) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(18)30395-5 · Cited by 262

The Insulinotropic Effect of Acute Exendin-4 Administered to Humans: Comparison of Nondiabetic State to Type 2 Diabetes

Egan, J. M. (2002) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.87.3.1282 · Cited by 256

Leptin inhibits insulin secretion by activation of phosphodiesterase 3B.

Zhao, A. Z., Bornfeldt, K. E., & Beavo, J. A. (1998) · Journal of Clinical Investigation · doi:10.1172/jci3920 · Cited by 236

Hyperglycemia and antipsychotic medications.

Haupt, D. W., & Newcomer, J. W. (2001) · PubMed · Cited by 233

Characterisation of the processing by human neutral endopeptidase 24.11 of GLP-1(7–36) amide and comparison of the substrate specificity of the enzyme for other glucagon-like peptides

Hupe-Sodmann, K., McGregor, G. P., Bridenbaugh, R., Göke, R., Göke, B., Thole, H., Zimmermann, B., & Voigt, K. (1995) · Regulatory Peptides · doi:10.1016/0167-0115(95)00063-h · Cited by 224

Rapid ATP‐Dependent Priming of Secretory Granules Precedes Ca 2+ ‐Induced Exocytosis in Mouse Pancreatic B‐Cells

Eliasson, L., Renström, E., Ding, W., Proks, P., & Rorsman, P. (1997) · The Journal of Physiology · doi:10.1111/j.1469-7793.1997.399bh.x · Cited by 223

Glucagon receptors on human islet cells contribute to glucose competence of insulin release

Huypens, P., Ling, Z., Pipeleers, D., & Schuit, F. (2000) · Diabetologia · doi:10.1007/s001250051484 · Cited by 222

Glucose Stimulates Translocation of the Homeodomain Transcription Factor PDX1 from the Cytoplasm to the Nucleus in Pancreatic β-Cells

Macfarlane, W. M., McKinnon, C. M., Felton-Edkins, Z. A., Cragg, H., James, R. F. L., & Docherty, K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.2.1011 · Cited by 219

Hypoglycaemia associated with use of inhibitors of angiotensin converting enzyme

Herings, R. M. C., de Boer, A., Leufkens, H. G. M., Porsius, A., & Stricker, B. H. C. (1995) · The Lancet · doi:10.1016/s0140-6736(95)91988-0 · Cited by 217

Characterization of SNARE protein expression in beta cell lines and pancreatic islets

Wheeler, M. B. (1996) · Endocrinology · doi:10.1210/en.137.4.1340 · Cited by 210

Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion.

Daniel, S., Noda, M., Straub, S. G., & Sharp, G. W. (1999) · Diabetes · doi:10.2337/diabetes.48.9.1686 · Cited by 210

Adrenergic Modulation of Basal Insulin Secretion in Man

Robertson, R. P., & Porte, D. (1973) · Diabetes · doi:10.2337/diab.22.1.1 · Cited by 209

Innervation of the pancreas by neurons in the gut

Kirchgessner, A., & Gershon, M. (1990) · The Journal of Neuroscience · doi:10.1523/jneurosci.10-05-01626.1990 · Cited by 206

Caffeine Ingestion Decreases Glucose Disposal During a Hyperinsulinemic-Euglycemic Clamp in Sedentary Humans

Greer, F., Hudson, R., Ross, R., & Graham, T. (2001) · Diabetes · doi:10.2337/diabetes.50.10.2349 · Cited by 206

Protein Kinases, Protein Phosphorylation, and the Regulation of Insulin Secretion from Pancreatic β-Cells.

Jones, P. M., & Persaud, S. J. (1998) · Endocrine Reviews · doi:10.1210/edrv.19.4.0339 · Cited by 205

Effects of tacrolimus (FK506) on human insulin gene expression, insulin mRNA levels, and insulin secretion in HIT-T15 cells.

Redmon, J. B., Olson, L. K., Armstrong, M. B., Greene, M. J., & Robertson, R. P. (1996) · Journal of Clinical Investigation · doi:10.1172/jci119105 · Cited by 204

Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic B cells predominantly via a regulated, rather than a constitutive, pathway.

Rhodes, C. J., & Halban, P. A. (1987) · The Journal of cell biology · doi:10.1083/jcb.105.1.145 · Cited by 203

PKC-Dependent Stimulation of Exocytosis by Sulfonylureas in Pancreatic β Cells

Eliasson, L., Renström, E., Ämmälä, C., Berggren, P.-O., Bertorello, A. M., Bokvist, K., Chibalin, A., Deeney, J. T., Flatt, P. R., Gäbel, J., et al. (1996) · Science · doi:10.1126/science.271.5250.813 · Cited by 194

Anchoring of protein kinase A facilitates hormone-mediated insulin secretion

Lester, L. B., Langeberg, L. K., & Scott, J. D. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14942 · Cited by 193

K ATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit

Drain, P., Li, L., & Wang, J. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.23.13953 · Cited by 193

Properties of cloned ATP‐sensitive K+ currents expressed in Xenopus oocytes.

Gribble, F. M., Ashfield, R., Ammälä, C., & Ashcroft, F. M. (1997) · The Journal of Physiology · doi:10.1113/jphysiol.1997.sp021843 · Cited by 193

Phosphodiesterases and Cyclic Nucleotide Signaling in Endocrine Cells

Conti, M. (2000) · Molecular Endocrinology · doi:10.1210/me.14.9.1317 · Cited by 191

Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.

Ammälä, C., Eliasson, L., Bokvist, K., Berggren, P. O., Honkanen, R. E., Sjöholm, A., & Rorsman, P. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.10.4343 · Cited by 187

Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose

Welsh, M., Scherberg, N., Gilmore, R., & Steiner, D. F. (1986) · Biochemical Journal · doi:10.1042/bj2350459 · Cited by 186

Neurotransmitter-Induced Inhibition of Exocytosis in Insulin-Secreting β Cells by Activation of Calcineurin

Renström, E., Ding, W.-G., Bokvist, K., & Rorsman, P. (1996) · Neuron · doi:10.1016/s0896-6273(00)80183-x · Cited by 186

Modeling Phasic Insulin Release

Nesher, R., & Cerasi, E. (2002) · Diabetes · doi:10.2337/diabetes.51.2007.s53 · Cited by 179

TRANSCRIPTIONAL INHIBITION OF INSULIN BY FK506 AND POSSIBLE INVOLVEMENT OF FK506 BINDING PROTEIN-12 IN PANCREATIC β-CELL

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