Regulation of Oligodendrocyte Differentiation and Myelination

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129

Training induces changes in white-matter architecture

Scholz, J., Klein, M. C., Behrens, T. E. J., & Johansen-Berg, H. (2009) · Nature Neuroscience · doi:10.1038/nn.2412 · Cited by 1,508

Structural maturation of neural pathways in children and adolescents: in vivo study

Paus, T., Zijdenbos, A., Worsley, K., Collins, D. L., Blumenthal, J., Giedd, J. N., Rapoport, J. L., & Evans, A. C. (1999) · Science · doi:10.1126/science.283.5409.1908 · Cited by 1,322

Extensive piano practicing has regionally specific effects on white matter development

Bengtsson, S. L., Nagy, Z., Skare, S., Forsman, L., Forssberg, H., & Ullén, F. (2005) · Nature Neuroscience · doi:10.1038/nn1516 · Cited by 1,193

A translational profiling approach for the molecular characterization of CNS cell types

Heiman, M., Schaefer, A., Gong, S., Peterson, J. D., Day, M., Ramsey, K. E., Suárez-Fariñas, M., Schwarz, C., Stephan, D. A., Surmeier, D. J., et al. (2008) · Cell · doi:10.1016/j.cell.2008.10.028 · Cited by 1,134

Common Developmental Requirement for Olig Function Indicates a Motor Neuron/Oligodendrocyte Connection

Lu, Q. R., Sun, T., Zhu, Z., Ma, N., Garcia, M., Stiles, C. D., & Rowitch, D. H. (2002) · Cell · doi:10.1016/s0092-8674(02)00678-5 · Cited by 1,087

Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus

Bergles, D. E., Roberts, J. D. B., Somogyi, P., & Jahr, C. E. (2000) · Nature · doi:10.1038/35012083 · Cited by 1,062

PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

Rivers, L. E., Young, K. M., Rizzi, M., Jamen, F., Psachoulia, K., Wade, A., Kessaris, N., & Richardson, W. D. (2008) · Nature Neuroscience · doi:10.1038/nn.2220 · Cited by 961

Oligodendrocyte dysfunction in schizophrenia and bipolar disorder.

Tkachev, D., Mimmack, M., Ryan, M. M., Wayland, M., Freeman, T., Jones, P., Starkey, M., Webster, M., Yolken, R., & Bahn, S. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14289-4 · Cited by 940

Myelination of a Key Relay Zone in the Hippocampal Formation Occurs in the Human Brain During Childhood, Adolescence, and Adulthood

Benes, F. M. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950060041004 · Cited by 744

Plasticity in gray and white: neuroimaging changes in brain structure during learning

Zatorre, R. J., Fields, R. D., & Johansen-Berg, H. (2012) · Nature Neuroscience · doi:10.1038/nn.3045 · Cited by 1,685

Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

Frühbeis, C., Fröhlich, D., Kuo, W. P., Amphornrat, J., Thilemann, S., Saab, A. S., Kirchhoff, F., Möbius, W., Goebbels, S., Nave, K.-A., et al. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001604 · Cited by 902

Oligodendrocytes: Myelination and Axonal SupportPreprint

Simons, M., & Nave, K. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020479 · Cited by 929

Myelin in the Central Nervous System: Structure, Function, and Pathology

Stadelmann, C., Timmler, S., Barrantes‐Freer, A., & Simons, M. (2019) · Physiological Reviews · doi:10.1152/physrev.00031.2018 · Cited by 799

Control of local protein synthesis and initial events in myelination by action potentials

Wake, H., Lee, P. R., & Fields, R. D. (2011) · Science · doi:10.1126/science.1206998 · Cited by 636

Glial Cells: Role of the Immune Response in Ischemic Stroke

Xu, S., Lü, J., Shao, A., Zhang, J. H., & Zhang, J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00294 · Cited by 626

Neuregulin-ERBB Signaling in the Nervous System and Neuropsychiatric Diseases

Mei, L., & Nave, K. (2014) · Neuron · doi:10.1016/j.neuron.2014.06.007 · Cited by 616

Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial

Green, A. J., Gelfand, J. M., Cree, B. A., Bevan, C., Boscardin, W. J., Mei, F., Inman, J., Arnow, S., Devereux, M., Abounasr, A., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)32346-2 · Cited by 593

Oligodendroglial NMDA receptors regulate glucose import and axonal energy metabolism

Saab, A. S., Tzvetavona, I. D., Trevisiol, A., Baltan, S., Dibaj, P., Kusch, K., Möbius, W., Goetze, B., Jahn, H. M., Huang, W., et al. (2016) · Neuron · doi:10.1016/j.neuron.2016.05.016 · Cited by 590

Dynamics of Oligodendrocyte Generation and Myelination in the Human Brain

Yeung, M. S. Y., Zdunek, S., Bergmann, O., Bernard, S., Salehpour, M., Alkass, K., Perl, S., Tisdale, J., Possnert, G., Brundin, L., et al. (2014) · Cell · doi:10.1016/j.cell.2014.10.011 · Cited by 541

Consensus Paper: Cerebellar Development

Leto, K., Arancillo, M., Becker, E. B. E., Buffo, A., Chiang, C. C., Ding, B., Dobyns, W. B., Dusart, I., Haldipur, P., Hatten, M. E., et al. (2015) · The Cerebellum · doi:10.1007/s12311-015-0724-2 · Cited by 509

Metformin restores CNS remyelination capacity by rejuvenating aged stem cells

Neumann, B., Baror, R., Zhao, C., Segel, M., Dietmann, S., Rawji, K. S., Foerster, S., McClain, C. R., Chalut, K., van Wijngaarden, P., et al. (2019) · Cell Stem Cell · doi:10.1016/j.stem.2019.08.015 · Cited by 449

Lifespan maturation and degeneration of human brain white matter

Yeatman, J. D., Wandell, B. A., & Mezer, A. (2014) · Nature Communications · doi:10.1038/ncomms5932 · Cited by 446

Leukodystrophies: a proposed classification system based on pathological changes and pathogenetic mechanisms

van der Knaap, M. S., & Bugiani, M. (2017) · Acta Neuropathologica · doi:10.1007/s00401-017-1739-1 · Cited by 403

Olig2 Targets Chromatin Remodelers to Enhancers to Initiate Oligodendrocyte Differentiation

Yu, Y., Chen, Y., Kim, B., Wang, H., Zhao, C., He, X., Liu, L., Liu, W., Wu, L. M. N., Mao, M., et al. (2013) · Cell · doi:10.1016/j.cell.2012.12.006 · Cited by 375

Development of white matter and reading skills

Yeatman, J. D., Dougherty, R. F., Ben‐Shachar, M., & Wandell, B. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1206792109 · Cited by 391

A novel m6A reader Prrc2a controls oligodendroglial specification and myelination

Wu, R., Li, A., Sun, B., Sun, J.-G., Zhang, J., Zhang, T., Chen, Y., Xiao, Y., Gao, Y., Zhang, Q., et al. (2019) · Cell Research · doi:10.1038/s41422-018-0113-8 · Cited by 366

Dynamics and Mechanisms of CNS Myelination

Bercury, K. K., & Macklin, W. B. (2015) · Developmental Cell · doi:10.1016/j.devcel.2015.01.016 · Cited by 320

Central nervous system myelin: structure, synthesis and assembly

Aggarwal, S., Yurlova, L., & Simons, M. (2011) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.06.004 · Cited by 301

Origin and dynamics of oligodendrocytes in the developing brain: Implications for perinatal white matter injury

van Tilborg, E., de Theije, C. G. M., van Hal, M., Wagenaar, N., de Vries, L. S., Benders, M. J. N. L., Rowitch, D. H., & Nijboer, C. H. A. (2017) · Glia · doi:10.1002/glia.23256 · Cited by 321

Myelin plasticity and nervous system function

Monje, M. (2018) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-080317-061853 · Cited by 274

Wrapped to Adapt: Experience-Dependent Myelination

Mount, C., & Monje, M. (2017) · Neuron · doi:10.1016/j.neuron.2017.07.009 · Cited by 262

BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions

Fard, M. K., van der Meer, F., Sánchez, P., Cantuti-Castelvetri, L., Mandad, S., Jäkel, S., Fornasiero, E. F., Schmitt, S., Ehrlich, M., Starost, L., et al. (2017) · Science Translational Medicine · doi:10.1126/scitranslmed.aam7816 · Cited by 249

Nonsynaptic junctions on myelinating glia promote preferential myelination of electrically active axons

Wake, H., Ortiz, F. C., Woo, D. H., Lee, P. R., Angulo, M. C., & Fields, R. D. (2015) · Nature Communications · doi:10.1038/ncomms8844 · Cited by 244

Oligodendrocyte lineage cells and depression

Zhou, B., Zhu, Z., Ransom, B. R., & Tong, X. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-00930-0 · Cited by 245

Myelin Gene Regulatory Factor Is Required for Maintenance of Myelin and Mature Oligodendrocyte Identity in the Adult CNS

Koenning, M., Jackson, S., Hay, C. M., Faux, C. H., Kilpatrick, T. J., Willingham, M. M., & Emery, B. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.1069-12.2012 · Cited by 231

Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain

Viganò, F., Möbius, W., Götz, M., & Dimou, L. (2013) · Nature Neuroscience · doi:10.1038/nn.3503 · Cited by 230

Glial Development: The Crossroads of Regeneration and Repair in the CNS

Gallo, V., & Deneen, B. (2014) · Neuron · doi:10.1016/j.neuron.2014.06.010 · Cited by 232

Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders

Spaas, J., van Veggel, L., Schepers, M., Tiane, A., van Horssen, J., Wilson, D. M., Moya, P. R., Piccart, E., Hellings, N., Eijnde, B. O., et al. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03802-0 · Cited by 224

White matter degeneration in vascular and other ageing‐related dementias

Hase, Y., Horsburgh, K. J., Ihara, M., & Kalaria, R. N. (2017) · Journal of Neurochemistry · doi:10.1111/jnc.14271 · Cited by 214

Myelin Membrane Assembly Is Driven by a Phase Transition of Myelin Basic Proteins Into a Cohesive Protein Meshwork

Aggarwal, S., Snaidero, N., Pähler, G., Frey, S., Sánchez, P., Zweckstetter, M., Janshoff, A., Schneider, A., Weil, M., Schaap, I. A. T., et al. (2013) · PLoS Biology · doi:10.1371/journal.pbio.1001577 · Cited by 206

American Thyroid Association Guide to Investigating Thyroid Hormone Economy and Action in Rodent and Cell Models: Report of the American Thyroid Association Task Force on Approaches and Strategies to Investigate Thyroid Hormone Economy and Action

Bianco, A. C., Anderson, G., Forrest, D., Galton, V. A., Gereben, B., Kim, B. W., Kopp, P. A., Liao, X. H., Obregon, M. J., Peeters, R. P., et al. (2014) · Thyroid · doi:10.1089/thy.2013.0109 · Cited by 205

Exosome-mediated shuttling of microRNA-29 regulates HIV Tat and morphine-mediated Neuronal dysfunction

Hu, G., Yao, H., Chaudhuri, A. D., Duan, M., Yelamanchili, S. V., Wen, H., Cheney, P. D., Fox, H. S., & Buch, S. J. (2012) · Cell Death and Disease · doi:10.1038/cddis.2012.114 · Cited by 206

ERK1/ERK2 MAPK Signaling is Required to Increase Myelin Thickness Independent of Oligodendrocyte Differentiation and Initiation of Myelination

Ishii, A., Fyffe-Maricich, S. L., Furusho, M., Miller, R. H., & Bansal, R. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.0137-12.2012 · Cited by 208

Cellular and molecular introduction to brain development

Jiang, X., & Nardelli, J. (2015) · Neurobiology of Disease · doi:10.1016/j.nbd.2015.07.007 · Cited by 222

Evolving Concepts of Gliogenesis: A Look Way Back and Ahead to the Next 25 Years

Freeman, M. R., & Rowitch, D. H. (2013) · Neuron · doi:10.1016/j.neuron.2013.10.034 · Cited by 202

Periods of synchronized myelin changes shape brain function and plasticity

de Faria, O., Pivoňková, H., Varga, B. V., Timmler, S., Evans, K. A., & Káradóttir, R. T. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00917-2 · Cited by 205

Notch and disease: A growing field

Louvi, A., & Artavanis‐Tsakonas, S. (2012) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2012.02.005 · Cited by 199

Beyond faithful conduction: Short-term dynamics, neuromodulation, and long-term regulation of spike propagation in the axon

Bucher, D. M., & Goaillard, J. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.06.001 · Cited by 189

Polymerized nano-curcumin attenuates neurological symptoms in EAE model of multiple sclerosis through down regulation of inflammatory and oxidative processes and enhancing neuroprotection and myelin repair

Mohajeri, M., Sadeghizadeh, M., Najafi, F., & Javan, M. (2015) · Neuropharmacology · doi:10.1016/j.neuropharm.2015.07.013 · Cited by 185

Myelin: A gatekeeper of activity-dependent circuit plasticity?

Bonetto, G., Belin, D., & Káradóttir, R. T. (2021) · Science · doi:10.1126/science.aba6905 · Cited by 195

Mutant Huntingtin Downregulates Myelin Regulatory Factor-Mediated Myelin Gene Expression and Affects Mature Oligodendrocytes

Huang, B., Wei, W., Wang, G., Gaertig, M. A., Feng, Y., Wang, W., Li, X., & Li, S. (2015) · Neuron · doi:10.1016/j.neuron.2015.02.026 · Cited by 179

Origin, lineage and function of cerebellar glia

Buffo, A., & Rossi, F. (2013) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.08.001 · Cited by 180

Dual-Mode Modulation of Smad Signaling by Smad-Interacting Protein Sip1 Is Required for Myelination in the Central Nervous System

Weng, Q., Chen, Y., Wang, H., Xu, X., Yang, B., He, Q., Shou, W., Chen, Y., Higashi, Y., van den Berghe, V., et al. (2012) · Neuron · doi:10.1016/j.neuron.2011.12.021 · Cited by 170

Role of Leucine-Rich Repeat Proteins in the Development and Function of Neural Circuits

de Wit, J., Hong, W., Luo, L., & Ghosh, A. (2011) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-092910-154111 · Cited by 168

Intrinsic and extrinsic control of oligodendrocyte development

Zuchero, J. B., & Barres, B. A. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.06.005 · Cited by 160

Demyelination as a rational therapeutic target for ischemic or traumatic brain injury

Shi, H., Hu, X., Leak, R. K., Shi, Y., An, C., Suenaga, J., Chen, J., & Gao, Y. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.03.017 · Cited by 159

Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair

Quintes, S., Brinkmann, B. G., Ebert, M., Fröb, F., Kungl, T., Arlt, F. A., Tarabykin, V. S., Huylebroeck, D., Meijer, D., Suter, U., et al. (2016) · Nature Neuroscience · doi:10.1038/nn.4321 · Cited by 151

Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS

Zhu, Q., Zhao, X., Zheng, K., Li, H., Huang, H., Zhang, Z., Mastracci, T., Wegner, M., Chen, Y., Sussel, L., et al. (2014) · Development · doi:10.1242/dev.095323 · Cited by 150

The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoA

Ackerman, S. D., Garcia, C. M., Piao, X., Gutmann, D. H., & Monk, K. R. (2015) · Nature Communications · doi:10.1038/ncomms7122 · Cited by 149

Myelin management by the 18.5‐kDa and 21.5‐kDa classic myelin basic protein isoforms

Harauz, G., & Boggs, J. M. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12195 · Cited by 161

Oligodendroglial Expression of TrkB Independently Regulates Myelination and Progenitor Cell Proliferation

Wong, A. W., Xiao, J., Kemper, D., Kilpatrick, T. J., & Murray, S. S. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3990-12.2013 · Cited by 149

Impaired oligodendrocyte maturation in preterm infants: Potential therapeutic targets

van Tilborg, E., Heijnen, C. J., Benders, M. J. N. L., van Bel, F., Fleiss, B., Gressèns, P., & Nijboer, C. H. A. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.11.002 · Cited by 159

Microglial transglutaminase-2 drives myelination and myelin repair via GPR56/ADGRG1 in oligodendrocyte precursor cells

Giera, S., Luo, R., Ying, Y., Ackerman, S. D., Jeong, S.-J., Stoveken, H. M., Folts, C. J., Welsh, C. A., Tall, G. G., Stevens, B., et al. (2018) · eLife · doi:10.7554/elife.33385 · Cited by 145

Development of Tract-Specific White Matter Pathways During Early Reading Development in At-Risk Children and Typical Controls

Wang, Y., Mauer, M. V., Raney, T., Peysakhovich, B., Becker, B. L. C., Sliva, D. D., & Gaab, N. (2016) · Cerebral Cortex · doi:10.1093/cercor/bhw095 · Cited by 148

Cell of all trades: oligodendrocyte precursor cells in synaptic, vascular, and immune functionPreprint

Akay, L. A., Effenberger, A. H., & Tsai, L. (2021) · Genes & Development · doi:10.1101/gad.344218.120 · Cited by 150

The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development

Giera, S., Deng, Y., Luo, R., Ackerman, S. D., Mogha, A., Monk, K. R., Ying, Y., Jeong, S., Makinodan, M., Bialas, A. R., et al. (2015) · Nature Communications · doi:10.1038/ncomms7121 · Cited by 139

A Size Barrier Limits Protein Diffusion at the Cell Surface to Generate Lipid-Rich Myelin-Membrane Sheets

Aggarwal, S., Yurlova, L., Snaidero, N., Reetz, C., Frey, S., Zimmermann, J., Pähler, G., Janshoff, A., Friedrichs, J., Müller, D. J., et al. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.08.001 · Cited by 139

Olig1 Function Is Required for Oligodendrocyte Differentiation in the Mouse Brain

Dai, J., Bercury, K. K., Ahrendsen, J. T., & Macklin, W. B. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.4962-14.2015 · Cited by 141

Biological development of reading circuits

Wandell, B. A., & Yeatman, J. D. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2012.12.005 · Cited by 128

White matter aging and its impact on brain function

Groh, J., & Simons, M. (2025) · Neuron · doi:10.1016/j.neuron.2024.10.019 · Cited by 124

The effect of glia-glia interactions on oligodendrocyte precursor cell biology during development and in demyelinating diseases

Clemente, D., Ortega, M. C., Melero‐Jerez, C., & de Castro, F. (2013) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00268 · Cited by 131

Brain-Derived Neurotrophic Factor in Central Nervous System Myelination: A New Mechanism to Promote Myelin Plasticity and Repair

Fletcher, J. L., Murray, S. S., & Xiao, J. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19124131 · Cited by 128

Lineage, fate, and fate potential of NG2-glia

Nishiyama, A., Boshans, L. L., Gonçalves, C. M., Wegrzyn, J., & Patel, K. D. (2015) · Brain Research · doi:10.1016/j.brainres.2015.08.013 · Cited by 128

The genome-wide supported microRNA-137 variant predicts phenotypic heterogeneity within schizophrenia

Lett, T. A. P., Chakavarty, M. M., Felsky, D., Brandl, E. J., Tiwari, A. K., Gonçalves, V. F., Rajji, T. K., Daskalakis, Z. J., Meltzer, H. Y., Lieberman, J. A., et al. (2013) · Molecular Psychiatry · doi:10.1038/mp.2013.17 · Cited by 121

Stage-Specific Deletion of Olig2 Conveys Opposing Functions on Differentiation and Maturation of Oligodendrocytes

Mei, F., Wang, H., Liu, S., Niu, J.-Q., Wang, L.-Y., He, Y.-T., Etxeberría, A., Chan, J., & Xiao, L. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2453-12.2013 · Cited by 109

Motor learning requires myelination to reduce asynchrony and spontaneity in neural activity

Kato, D., Wake, H., Lee, P. R., Tachibana, Y., Ono, R., Sugio, S., Tsuji, Y., Tanaka, Y. H., Tanaka, Y. R., Masamizu, Y., et al. (2020) · Glia · doi:10.1002/glia.23713 · Cited by 114

Zeb2: A multifunctional regulator of nervous system development

Hegarty, S. V., Sullivan, A. M., & O’Keeffe, G. W. (2015) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.07.001 · Cited by 113

Autophagy is essential for oligodendrocyte differentiation, survival, and proper myelination

Bankston, A. N., Forston, M. D., Howard, R. M., Andres, K. R., Smith, A. E., Ohri, S. S., Bates, M. L., Bunge, M. B., & Whittemore, S. R. (2019) · Glia · doi:10.1002/glia.23646 · Cited by 112

Identification of a Gene Regulatory Network Necessary for the Initiation of Oligodendrocyte Differentiation

Swiss, V. A., Nguyen, T., Dugas, J., Ibrahim, A., Barres, B., Androulakis, I. P., & Casaccia, P. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018088 · Cited by 112

White matter integrity in mice requires continuous myelin synthesis at the inner tongue

Meschkat, M., Steyer, A. M., Weil, M.-T., Kusch, K., Jahn, O., Piepkorn, L., Agüi-Gonzalez, P., Phan, N. T. N., Ruhwedel, T., Sadowski, B., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28720-y · Cited by 112

Developmental Origins of Astrocyte Heterogeneity: The final frontier of CNS development

Chaboub, L. S., & Deneen, B. (2012) · Developmental Neuroscience · doi:10.1159/000343723 · Cited by 103

Valproic acid increases white matter repair and neurogenesis after stroke

Liu, X., Chopp, M., Kassis, H., Jia, L., Hozeska‐Solgot, A., Zhang, R. L., Chen, C., Cui, Y. S., & Zhang, Z. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.06.012 · Cited by 111

Analysis, occurrence, and function of 9-cis-retinoic acid

Kane, M. A. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · doi:10.1016/j.bbalip.2011.09.012 · Cited by 111

miR-221/222 promote Schwann cell proliferation and migration by targeting LASS2 following sciatic nerve injury

Yu, B., Zhou, S., Wang, Y., Qian, T., Ding, G., Ding, F., & Gu, X. (2012) · Journal of Cell Science · doi:10.1242/jcs.098996 · Cited by 108

B-1a lymphocytes promote oligodendrogenesis during brain development

Tanabe, S., & Yamashita, T. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0106-4 · Cited by 109

Myelin inhibits oligodendroglial maturation and regulates oligodendrocytic transcription factor expression

Plemel, J. R., Manesh, S. B., Sparling, J. S., & Tetzlaff, W. (2013) · Glia · doi:10.1002/glia.22535 · Cited by 107

Few Smad proteins and many Smad-interacting proteins yield multiple functions and action modes in TGFβ/BMP signaling in vivo

Conidi, A., Cazzola, S., Beets, K., Coddens, K., Collart, C., Cornelis, F. M. F., Cox, L., Debruyn, J., Dobreva, M. P., Dries, R., et al. (2011) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2011.11.006 · Cited by 103

Npc1 Acting in Neurons and Glia Is Essential for the Formation and Maintenance of CNS Myelin

Yu, T., & Lieberman, A. P. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003462 · Cited by 103

Biphasic Mechanisms of Neurovascular Unit Injury and Protection in CNS Diseases

Maki, T., Hayakawa, K., Pham, L. D., Xing, C., Lo, E. H., & Arai, K. (2013) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527311312030004 · Cited by 103

Axon-glia interaction and membrane traffic in myelin formation

White, R., & Krämer‐Albers, E. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2013.00284 · Cited by 109

Prenatal maternal and childhood bisphenol a exposure and brain structure and behavior of young children

the APrON Study Team, Grohs, M. N., Reynolds, J. E., Liu, J., Martin, J. W., Pollock, T., Lebel, C. A., & Dewey, D. (2019) · Environmental Health · doi:10.1186/s12940-019-0528-9 · Cited by 103

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Reviewed by:

Barca-mayo, O., Lu, Q. R., Lu, Q. R., & Department Of (2012)